LOCUS       c00009_NZ_JHWC..       15984 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JHWC01000009.1 Helicobacter rodentium ATCC 700285
            BS85DRAFT_scaffold00009.9_C, whole genome shotgun sequence.
ACCESSION   NZ_JHWC01000009
VERSION     NZ_JHWC01000009
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:39:29
            Original ID  :: NZ_JHWC01000009.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15984
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15984
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3267:5984]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3268..5984
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15984
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15984
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(111..1451)
                     /locus_tag="ctg9_1"
                     /transl_table=11
                     /translation="MRVATHLDYNPTLHFISDDSREVFNADITPSNCAFLITQSNKNYV
                     ESAKKNGFEIFITPKDLINYFDLNLKLVGITGTNGKTTTAAMIYSILLDFGFSVALLGT
                     RGFFINGQEKRPKGLTTPSLLEIYSAIHEARQENCTHFIMEVSSHAIVQNRIEGLEFDL
                     RILTNITSDHLDYHKTLENYIAVKNSFFSNPLHLKLLNKDEPNAHYAPQKAITYGIESP
                     ATLNVKAYSLNNGITAQIAYGKEEANIECTLFGKHNLYNALAAIGAVKLLEDFPLREIC
                     EKLENFGGVLGRMQVVHQNPLIIVDFAHTEDGMEKIFQSFLHKKIVVVFGAGGDRDRSK
                     RPKMGLCAAKYAQKLYITSDNPRSEIPSAIMQEILGGIPQELRNHREIHLEESRAKAIA
                     MAVKNLKSDEILLILGKGDETYQIIGKETLHFDDCEEVQKALKSLAS"
     CDS             complement(1463..2062)
                     /locus_tag="ctg9_2"
                     /transl_table=11
                     /translation="MAKDFAYFKRKAKLAFNKRQYLYVLEILSYAQILLDCLNEKESLH
                     LNMLGTLADMALEYEDEARALFEYYQVICNKSNQEAEKVILEMIENFDKNLYALNLAIW
                     SLQEAEVDKNDGILYEDFEIHSAKVGFKEAFEDLMFSSKIIFTSKSEFLIFVRNLVKFG
                     FEEIAINYFENAGNLLFYDKDFMRLYQQILQNKKIN"
     CDS             complement(2085..2330)
                     /locus_tag="ctg9_3"
                     /transl_table=11
                     /translation="MLPFSDEELLKPVEKSIDKVRPMLIKDGGNVTLIKIENGKVFVRL
                     IGACKGCPSSAQTLKFGIERTLKNDIHPDIEIINVP"
     CDS             2525..3256
                     /locus_tag="ctg9_4"
                     /transl_table=11
                     /translation="MQNDEVVIESYLKVTSERKKRRNPARWDMLQSITGAILAIFILFH
                     MCFTSSIMLGQDAFNAVVHFSEGSFIFGGNGIPLLTTLVVVIISVVFVAHAFLAMRKFP
                     ANFQQFMIFKTHKSLMKHCDTTLWWIQFLTGFALFFLGGAHLVTILFNSTDINAITSAS
                     RFVNGNLAEFYLVLLVVMVLHASIGMYRLIIKWVPLEAPTTAQSNVKRKNVKIAVFAVF
                     IVLGVIAFIADFTWIALGKSL"
     CDS             3268..5241
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 421.5; E-value:
                     1.3e-128)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.7e-128,
                     bitscore: 421.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 9.2e-39,
                     bitscore: 124.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIVYSDALVIGGGLAGLRAAVACKQKGLSTIVLSLIPVKRSHSA
                     AAQGGMQASLGNSKMSDGDNEDLHFADTVKGSDWGCDQKVARMFVTTAPKAIRQLAAWG
                     VPWTRIKKGDRTAVINAQKTTITEEDFRHGLIHSRDFGGTKKWRTCYTADATGHSMLFA
                     VANEALKNGVDIHDRKEAIALIHHNNRCYGAIVRDLVSGELIGYVARGTLIATGGYGRI
                     YKDTTNAVICEGIGTAIALETGIAKLGNMEAVQFHPTGLFPSGILLTEGCRGDGGVLRD
                     VDGYRFMPDYEPEKKELASRDVVSRRMIQRIREGKGVSSPYGEHLWLDISILGRKHIET
                     NLRDVQEICECFAGIDPAEKWAPVKPMQHYCMGGIRTNAKGETALKGLFSAGEAACWDL
                     HGFNRLGGNSVSEAVVSGMIIGDYFAENCLGSHADIETKLVEECIEKQQKYLQSILDNT
                     GTENVFEIKDRMKQIMGDKVGIFRDGEHLASAVSELEQLYIRSKNIGIKTKRLSANPEL
                     EEAYRVPKMLKIALCVAKGALDRTESRGAHSREDYPKRDDQNWLKRTLASWEDPNQTLP
                     TLTYEALDIATMEMAPGFRGYGAKGMIIENPESLKRQEQIDKIRSDMEAQGKDRYEIQE
                     ALMPFELQPYYKARNERIGDKQ"
     CDS             5238..5984
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 108.4; E-value: 6.2e-34)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_6"
                     /sec_met_domain="Fer2_3 (E-value: 8e-34, bitscore: 108.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1.4e-10, bitscore: 34.0,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00043, bitscore: 13.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGAVESSNRELTIRVLKFNPNSAVSKPHFAEYKLKEAHSMTVFI
                     VLNMIREQYDPDLSFDFVCRAGICGSCGMMINGRPRLACRTLTKDFPDGVITLMPLPAF
                     KLLKDLSVDTGNWMNGMSKRVESWIHAQEKSEEHMCQIEERVEPEVAAEVFELDRCIEC
                     GCCIASCGTKLMREDFVGAAGFNRVVRFMLDPHDERTDSDFYELVGDDNGVFGCMSLLA
                     CHDVCPKNLPLQSKIAYLRRKMATAK"
     CDS             6676..7611
                     /locus_tag="ctg9_7"
                     /transl_table=11
                     /translation="MIVNNASSVAVNSSILAPTNLKSLSKLQEEEKTDSPLDLKNLSKD
                     KVVVVFDDAVSGNRYGIEITRENLQRLQEKFETNNFYQRKDSTIRLNGKAESYVSGWFG
                     EVAYNMEALKAETNSEGKFTAKGKESIKDDFYFSLEAEETGAGYIAGNFEVTQHIAYKA
                     GKYESIDAMINQLITEDRDFNGVVSVSEHFSKPGELQRAISDTIESGKCKNCEKTLLEK
                     LKDLEKLGIKSNRDSKDEAMRLLSRLRQSGNVESLNIKEQELLKKYFASEVERIKNEES
                     KTERQSFHQAIVCFAEKIYSNESLALNLKV"
     CDS             complement(7656..8210)
                     /locus_tag="ctg9_8"
                     /transl_table=11
                     /translation="MKKLLTTTLTTALGIGLASSMAFAADLYNPKDEKNHLVIPMEALS
                     QEGNKNVGEVIAVETKYGVAFYPNLQGIASGLHGFHIHENPDCGATEKGLGMKAGGHWD
                     KYKTNAHSYPWSDKGHIGDLPALYVDEKGVANNPVLSPKIKTLAELKNHSLMIHVGGDN
                     HHDTPAALGGGGARMVCGVIK"
     CDS             complement(8273..8872)
                     /locus_tag="ctg9_9"
                     /transl_table=11
                     /translation="MKQWILSTLALIILPIWAAENQREVIDCNIIFEQRKAEIIKEIER
                     IDEQQQALQALQSATQNVLDQKEADLKKREIALNNAQKEMEEREAKIARLVKRNEEILK
                     QIRGATQSKVGETYAGMKDSKSAAILESLPDAEAAGILYALDTKVMSKILSKMTPQKAA
                     TLTQLLQKGPPFEEEKESPQPNNAIQNKENNEGSAI"
     CDS             complement(8869..9294)
                     /locus_tag="ctg9_10"
                     /transl_table=11
                     /translation="MKTKFTQLVLLHKKKVDEIEMMLQKNAQVILIKQNEIDTLVQEFA
                     TLQSPTNGIYQNFLTFVHHKEEFRQMIDFKIQELALLKHERQKLQEDFKRQNIEFEKAK
                     YLDGLEVKKRLEQIKKQEMRDLDEISVMLYANHKEKQ"
     CDS             complement(9318..10574)
                     /locus_tag="ctg9_11"
                     /transl_table=11
                     /translation="VSKADLIVGIQWGDEGKGKMVDLLAQHYDYVVRYQGGHNAGHTIV
                     VGGKKYALHLIPSGILYPQCKNIIGNGVVISPNALIEEMQQFEEMYGNLQGRLFISTKA
                     HLILPYHETLDRLSEEQAKQAIGTTCKGIGPTYTDKVSRRGIRAEELRDTETLAKKILE
                     KLEDIAKKGIPIEIPTLESLKQELDHYAKVLLPLLTNTTNMLWRAMDEGKKILCEGAQG
                     SMLDIDFGTYPFVTSSTTISAGACNGTGIAPRELGEVIGIIKAYCTRVGNGPFPTEEIG
                     SIGESLRNKGREFGVTTGRARRCGWLDAMAVKYACRLNGANALAMMKLDVLDGFEQIKV
                     CIAYENENGTRLEEFPSNLTNVKPIYKTFQGWDKTEKIREFDKLPQNAQKYILELEKFI
                     GVKIKMISTSPDRNDTIFR"
     CDS             complement(10584..11462)
                     /locus_tag="ctg9_12"
                     /transl_table=11
                     /translation="VILSHEIPQGCKLYFGKNAKFKRELESLASEILYQNGYEEIVTPT
                     FAYLKHQRDTHSREVVRTNNQYNHQIALRNDSTIDTIRLLAPHLREATISKRWFYIQPI
                     FIYPTTEVHQIGVENLENCDILPFIQISLQLLNGITNFTESSNIQNIKAFLQLANVKIP
                     QICAEIFRIPLTAFEKIDIGAIENTNPLMAKLLRVYNQETLKEFLQDSTYNLPSELKLE
                     LEKLYNLASEIHYAHCIVSPLYYAPMSYYKGLFFRFFANNTTLILGGEYKILEQNACGF
                     GVYTDNLIQFI"
     CDS             11769..12260
                     /locus_tag="ctg9_13"
                     /transl_table=11
                     /translation="MAFKINTQAYQIRYPKPSPSAPINDPKEESPIKNTIQTGNPTTKP
                     QIKFPSHNLLDKYNSAGSYYNFQNILNNQLGIKNNNQSNSDDEGKKALLENLQQQSNAF
                     NHGISGSGDSKLNWSDALGQYLELEDSVLHKKLQDEQNEQAQSDFLNELLWNLKKNLPL
                     "
     CDS             12347..13615
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Homoserine_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_14"
                     /sec_met_domain="Homoserine_dh (E-value: 2.9e-66, bitscore:
                     215.0, seeds: 932, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLTIGIIGLGTVGSSVAKILKDNQALIAARAGYTIHIKQGVVK
                     DLSKSRQVFDFPITNEIDSVLNDSEIDIIVELTGGVDEPFEIAKKALRNSKAFVTANKA
                     MLAYHRYELQKIAGDLPIGFEASVAGGIPIIKALRDGLGANHILSIRGIINGTCNFILT
                     KMKEQGVEYEEVLQEAQDLGYAEADPTFDVGGFDAAHKLLILASIAYGIDAKPEDVLIE
                     GITQITQEDIAFAKEFGYHLKLLGIARKDGEEIELRVHPTLLPKDAMIGKVDGVMNAIS
                     VVGDCVGETLYYGAGAGGNATASAVISDIIEIARTKSSPMLGFKNISNTLRLKPLDKIV
                     SAYYLRILVLDKPGVLAKIATIFGEVGISIDTFLQRKAKDKAHSTLLLSTHTCTEAEIK
                     IALKRISDLEIVCAAPVMIRIEK"
     CDS             13677..14039
                     /locus_tag="ctg9_15"
                     /transl_table=11
                     /translation="MQKLYNTTQKGREAEDCACEFLIEQGFVVLERNFHTRFGELDIIA
                     KKDGILHFVEVKSGIGFEPVYNLSPAKLKKLTKTLNIYLEKHHIQDSYCLSALILSKQS
                     ANDIFQVHWLENLTIF"
     CDS             14644..15795
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_q6"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_16"
                     /sec_met_domain="Oxidored_q6 (E-value: 5e-32, bitscore:
                     102.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKEQTLLRQAEERLAKLAKFPALKKGDSIKKMLKEKGISRRDFM
                     KWAGAMTAMLSLPASFTPLTAKAAEVADRLPVIWLHLAECTGCSESLLRSDGPGIASLI
                     FDYISLEYHETIMAASGYQAEENLESAIERYKGRYVLMVEGGVPTGLDGQYLTIGAFGH
                     TGLQNAKTASENAAAIFAIGTCSSFGGIQAANPNPTAAKPLSAVTNKPVINVPGCPPSE
                     KNIVGNVIHFLLFGTLPQLDAFNRPKWAYGLRIHDLCERRGHFDAGEFVQTFGDEGAKN
                     GYCLYKVGCKGPYTFNNCSKLRFNSHTSWPIQAGHGCIGCSEPNFWDTMGPFEEPLANK
                     LYDTPFFGGADRTADNIGITLLGAAAIGMAAHAVLSAVRKDKE"
ORIGIN
        1 accacgactt cctacgaagt ctcgcaatga caaagtggga aggttcataa tgacagcaga
       61 gtaatcttgc gatgacgagg cggtaagtat tcctctatac aattttcata ttacgaagca
      121 agagatttaa gagccttttg cacctcttcg cagtcgtcaa aatgcagggt ttctttgccg
      181 atgatttggt aagtttcatc gcctttgcct agaatcaata atatttcatc gcttttgaga
      241 ttcttaaccg ccattgcaat cgccttagcg cgactttctt ctaagtggat ttcacgatga
      301 tttcttaatt cttgcgggat tccacctaga atctcttgca taatggcact tggaatctca
      361 ctgcgtggat tatcgcttgt gatatagagt ttttgtgcat atttagcggc acatagcccc
      421 attttagggc gtttactcct gtctctatcg cctcctgcgc caaagacaac aacgattttt
      481 ttgtgcaaaa aggattgaaa gattttttcc attccgtcct ctgtgtgtgc aaaatctaca
      541 atgatgaggg ggttttgatg cacaacttgc attctgccta acacaccgcc aaaattttct
      601 aatttttcac aaatttctcg caaaggaaaa tcctctagta gtttgactgc accgattgct
      661 gcaagggcgt tgtagagatt gtgtttgcca aaaagtgtgc attcaatgtt cgcttcctct
      721 ttgccatagg caatttgtgc ggtgattcca ttgtttaggc tgtaagcttt aacattaagg
      781 gttgcggggg attctatgcc ataagtgatt gccttttgtg gcgcataatg cgcatttggt
      841 tcgtctttgt ttaggagttt caaatggagt ggattagaaa aaaaggaatt tttcaccgca
      901 atgtaatttt ctaaagtctt gtggtaatcc aaatggtcgc ttgtgatatt ggttagaatc
      961 cgcaaatcaa actctagccc ctcaatgcgg ttttgcacga ttgcgtggga gctaacctcc
     1021 attataaagt gtgtgcaatt ttcttgcctt gcctcgtgga ttgcgctata aatttctagc
     1081 aaacttgggg ttgtaagtcc tttgggacgc ttttcttgtc cattgataaa gaatccacgt
     1141 gttccaagca gtgcaacaga gaatccaaaa tcaagcaata tggaataaat catcgccgcg
     1201 gtggtggttt tgccatttgt gcctgtaatg ccaacaagtt ttaagtttaa atcaaaatag
     1261 ttgattaaat cttttggagt gataaaaatt tcaaatccat ttttctttgc ggattccaca
     1321 taatttttgt tgctttgcgt gattaaaaag gcgcagttgc taggcgtgat gtctgcgtta
     1381 aagacttcgc gcgaatcgtc actgatgaag tgaagagtgg gattataatc caaatgggta
     1441 gctactcgca tagatttcct tattaattta tttttttgtt ttgcaggatt tgctgataaa
     1501 gacgcataaa atctttatca taaaacaata aatttcccgc gttttcaaaa taattgattg
     1561 caatctcttc aaatccaaac tttactaaat tacgcacaaa aatcaaaaat tcacttttgc
     1621 tagtaaaaat aatcttggag ctaaacatta aatcctcaaa agcttctttg aagccaactt
     1681 ttgcggaatg aatttcaaaa tcctcataca agattccatc atttttatcc acttctgctt
     1741 cttgcaaact ccaaattgca agattgagag cataaagatt tttatcaaaa ttttcaatca
     1801 tttctaaaat gactttttct gcttcttggt tgcttttgtt gcagattact tgataatact
     1861 caaacaaagc gcgcgcttca tcttcgtatt ctaatgccat atctgcaagt gtgccgagca
     1921 tatttaaatg tagcgattct ttctcgttta aacaatctag taaaatctgc gcataagata
     1981 gaatctccaa aacatataaa tattgtcgtt tgttgaaagc gagtttagct tttctcttga
     2041 aatatgcaaa gtcttttgcc attgtcagcc ttaaagaatt tagtttatgg gacattaata
     2101 atttcaatgt cagggtgaat atcatttttc aatgtgcgtt caatgccaaa ttttaaggtt
     2161 tgtgcgctac ttggacaacc cttacatgca ccgataagac gcacaaaaac tttgccattc
     2221 tcaattttaa tgagtgtaac atttccgcca tcttttataa gcattgggcg gactttgtca
     2281 atactctttt ctacgggttt taacaattct tcatcactaa agggaagcat aatttttcct
     2341 taattttaaa atttaaaatt ttatcaaaga tgcgataata cttaagtttt cttaaagttg
     2401 taataaaaaa cttctttaat atttaatata attttatcta aaatgtttta taatgttgag
     2461 atttcttagg ttttatgcgg tgtgcgaaag cattgtgata tatttctact ttttaggagg
     2521 atttatgcaa aatgatgaag tagtgattga gagttattta aaggtaactt cagagcgcaa
     2581 aaaaagacga aatcctgcgc gttgggatat gttacaaagt attacaggag ctattttagc
     2641 gatttttatt ttgtttcata tgtgttttac atcttctatt atgttggggc aagacgcatt
     2701 taatgcggtt gtgcatttta gtgaaggatc atttattttt ggtggaaatg ggattccgct
     2761 tttaacaact ttagtggttg ttatcattag cgttgtattt gtagcccacg catttttggc
     2821 gatgagaaaa ttccctgcaa acttccagca gtttatgatt tttaaaacac ataaatcttt
     2881 gatgaagcat tgtgatacaa cgctttggtg gattcagttt ttaacaggat ttgcattgtt
     2941 tttcttgggt ggtgcgcatt tggttacgat tctttttaat tccacagata ttaatgcgat
     3001 tacttctgcg tcaagatttg tcaatggtaa tttagcggaa ttttatcttg ttttattggt
     3061 ggttatggtg ttgcacgcaa gcattggaat gtatcgcttg attatcaaat gggttccact
     3121 tgaagcacca acaacagcgc aaagcaatgt caagcgcaaa aatgttaaga ttgctgtatt
     3181 tgcagtattt atcgttttag gggtgattgc atttatcgcg gacttcactt ggattgcctt
     3241 aggcaaaagt ctataaagga gagataaatg aaaatagtat atagtgatgc attagtcatt
     3301 ggtggaggtt tggcaggatt gcgtgcagca gtagcctgta agcaaaaggg attaagcacg
     3361 attgttttaa gtttaattcc ggttaaaaga agccactctg cagcggcgca aggcggtatg
     3421 caagcaagtc ttgggaactc caaaatgagt gatggagaca acgaggattt acactttgca
     3481 gataccgtaa aaggaagtga ttggggttgc gaccaaaaag ttgcaagaat gtttgttact
     3541 acagctccta aagcgattcg tcaattagca gcgtggggag tgccttggac tagaatcaaa
     3601 aagggcgata gaacagcagt tattaatgct caaaagacaa ccattactga agaggatttt
     3661 agacacggat taattcattc ccgtgacttt ggtggaacca aaaaatggag aacttgttat
     3721 acagcagacg cgacaggaca ttctatgttg tttgcagtag caaatgaagc tttaaaaaat
     3781 ggtgtggata ttcacgatag aaaagaagcg attgctctaa tccaccataa taatcgctgc
     3841 tatggtgcga ttgtgcgtga tttggttagt ggagagttga ttgggtatgt tgcaagagga
     3901 acattgattg caacaggtgg atatggtaga atctacaaag atacaaccaa tgccgtaatt
     3961 tgtgagggaa tcggaactgc aatcgcatta gaaactggaa ttgcaaaatt aggaaatatg
     4021 gaagcggtgc aatttcaccc aaccggattg tttccaagtg gaatcttgct aacagaaggt
     4081 tgtcgtggag acggcggggt tttgcgtgat gtagatggat accgctttat gccagattat
     4141 gagccagaga aaaaagagct tgcaagccgt gatgttgttt caagaagaat gattcaaaga
     4201 atccgcgaag gtaaaggtgt aagctctcct tatggtgagc atttatggct tgatatttca
     4261 atcttgggac gcaaacatat tgaaacaaac ttgcgtgatg tgcaagaaat ttgtgaatgt
     4321 tttgccggaa ttgatcctgc ggaaaaatgg gctccagtga agccaatgca acactattgt
     4381 atgggtggaa tccgcacaaa tgctaaggga gaaactgcat taaaagggtt attttcagct
     4441 ggtgaagctg cgtgttggga tttacacgga tttaaccgct taggtggaaa ctctgtgagt
     4501 gaagcggtgg ttagcggtat gattattgga gattattttg cagaaaactg cttaggttct
     4561 cacgcagaca ttgaaacaaa acttgtagaa gaatgtattg agaagcaaca aaaatatctt
     4621 caaagtatct tggacaatac cggaacagaa aatgtttttg aaatcaaaga cagaatgaaa
     4681 cagattatgg gtgataaagt tggaatcttt agagatgggg aacatttggc ttctgctgtg
     4741 agtgagttgg aacaacttta tattcgtagc aaaaatatcg gaatcaaaac taaacgcctt
     4801 tcagcaaatc ctgaactaga ggaagcttat cgtgtgccaa aaatgttgaa aattgctctt
     4861 tgtgttgcta aaggtgcatt ggatagaaca gaatcccgcg gagcgcatag tcgtgaggat
     4921 tatccaaaga gagatgatca aaattggttg aagcgcacat tggcgagttg ggaagatcca
     4981 aaccaaacat tacctacatt aacttatgaa gcactagata ttgcgacaat ggaaatggct
     5041 cccggattcc gcggatatgg tgcaaagggt atgattattg agaatccaga aagcttaaag
     5101 cgtcaagaac aaattgataa aattcgctcg gatatggaag cacaaggtaa agatcgctat
     5161 gaaatccaag aagccttaat gccatttgaa ttgcaaccat attataaagc gcgcaatgaa
     5221 agaataggag ataaacaatg agtggagctg ttgagagtag caatagagaa ttaacaatta
     5281 gagtgttgaa gtttaatccc aatagtgcag tatctaagcc gcacttcgca gaatataaac
     5341 tcaaagaagc gcattctatg acggttttta tcgtattgaa tatgattcgt gagcagtatg
     5401 atcctgattt aagctttgac tttgtgtgtc gtgcggggat ttgtggaagc tgtggaatga
     5461 tgattaatgg gcgtccaaga cttgcgtgta gaacattgac aaaagatttt cctgatggtg
     5521 taattacttt aatgccattg cctgcattta agcttctcaa agacttatct gtggatacag
     5581 gaaattggat gaatggaatg agcaaacgcg tagaaagctg gattcacgca caagaaaaaa
     5641 gcgaagagca tatgtgtcag attgaagagc gcgtagagcc tgaagttgct gcagaagttt
     5701 ttgagcttga tcgttgtatt gagtgtggtt gttgtattgc ttcttgtgga acaaaactta
     5761 tgcgtgaaga tttcgtaggt gctgcgggat tcaatcgtgt tgtaagattt atgctagacc
     5821 cacacgatga gcgcacagat tcagattttt atgagttggt tggtgatgat aatggtgtgt
     5881 ttggttgtat gagcttactt gcttgccacg atgtttgccc taaaaactta ccattgcaaa
     5941 gcaaaattgc ttacctaaga cgcaaaatgg cgactgcaaa gtaaaatttc tataaatctt
     6001 ggaatctttt ttggattcca agattacatt tattttttta ttgtataatt ctatcctttt
     6061 ttagagaggt gtccgagtgg ttgaaggagc acgcctggaa cgcgtgtaag gtgcaagcct
     6121 tcgagggttc gaatcccttc ctctctgcca ttagtatttt acaaatttcc ttagaatcct
     6181 caattctagc tttagcaatt tgcttttaca agtccataat cttaaatcct ctccataact
     6241 aatgtgtttg tcattgcaag atttcatttt gtaacaaata taagagaaag tttaaaaatt
     6301 tttacctttt tagttggttt taattttgat ttgataataa agatgcttta atttataaat
     6361 taaattggag cattagtatt ttttttaata aagaaaaatt ataaaaaagt tatttttagt
     6421 ttattggttg tttcatcttt ggtaagtatc tcgtatgcag aggattggtt gtcattattt
     6481 tttggtagtc tatttggtaa taatgtgcag gaaaatttca atgcagagga aatacgacaa
     6541 gaggatagga gaattagctt tgagacaaac aatagcaaaa tctacgcaaa tgcttggaaa
     6601 aaatatcaaa ataaccccaa tagatgccct ataaatcggt ggggacagcc tatgtgtaaa
     6661 ttttaaagga atacaatgat tgtcaataac gcttctagtg tagcggtaaa tagttctatt
     6721 cttgcaccca caaatcttaa aagcctctcc aaattacaag aggaggaaaa aacagattct
     6781 cctcttgatt taaaaaatct ctcaaaagat aaggtggttg tagtgtttga tgacgcagtc
     6841 agtggcaatc gctatggcat tgaaattact agagagaatt tgcaaaggct acaagagaag
     6901 tttgagacaa acaacttcta tcaacgcaaa gatagcacga ttcgcctcaa tggcaaagcg
     6961 gaatcctatg tcagtggttg gtttggtgaa gtggcttata atatggaggc gttgaaagca
     7021 gaaacgaata gtgagggtaa attcacagca aaagggaaag aatccatcaa agatgatttt
     7081 tatttttcgc ttgaagcaga ggagacggga gcgggttata tcgcgggtaa ttttgaagtt
     7141 acacagcata ttgcatacaa agcaggaaaa tatgagagta ttgatgcaat gataaatcaa
     7201 ctcatcacag aggataggga ttttaatggt gtggtaagcg tgagcgagca tttctctaag
     7261 ccgggcgaat tgcaaagggc gatttctgat accatagaaa gtggaaaatg caagaattgc
     7321 gaaaaaaccc tacttgaaaa acttaaggat ttagaaaaat taggaatcaa aagcaacagg
     7381 gattctaaag atgaggcaat gcgattgctt tctaggctta ggcaaagtgg caatgtagaa
     7441 tcgctaaata tcaaagagca agaattgtta aaaaagtatt ttgcaagtga ggtggagaga
     7501 atcaaaaatg aggaatccaa aacagagaga caatctttcc atcaagccat cgtttgtttt
     7561 gcagaaaaaa tttattccaa tgagagttta gctttaaatc tcaaagttta aatttattta
     7621 agtttgctag aatcctaaga ttctagcaag ttagactatt taatcactcc gcaaaccatt
     7681 ctagcaccac ctccaccaag tgctgcagga gtatcgtggt gattgtctcc tcctacgtga
     7741 atcattaaag aatggttttt taattctgct aaagttttga ttttggggga tagaacggga
     7801 ttgtttgcta cacctttttc atctacataa agtgcaggta aatccccaat gtgtccttta
     7861 tcgctccaag gataagagtg tgcatttgtc ttatatttat cccaatgccc tccagctttc
     7921 attcctaagc ctttttctgt tgcaccacaa tcaggatttt cgtggatatg gaatccgtgc
     7981 aaaccacttg caatgccttg taggtttgga tagaatgcga caccatattt tgtttctacg
     8041 gcgataactt cgcctacatt tttgttgccc tcttggctta aagcctccat tggaatcacc
     8101 aaatgatttt tttcatcttt tgggttataa aggtcagcag caaaagccat actagaggct
     8161 aacccgattc caagtgcagt tgtcaatgtt gttgtaagaa gttttttcat tgtttttcct
     8221 tatatgttaa tttaggtttt aattataaca tattcactaa ggtttagttt tattaaattg
     8281 cacttccttc attgttttct ttgttttgta ttgcattatt gggttgtggc gattctttct
     8341 cctcttcaaa aggaggtcct ttttgcaata attgcgtaag tgtagcggct ttttgtggcg
     8401 tcattttgga taaaattttg ctcattactt ttgtatcaag cgcatagaga atccctgccg
     8461 cttctgcatc aggcaaagat tctaggattg cggcagattt ggaatctttc atacctgcat
     8521 aagtttcgcc taccttgctt tgtgttgccc ctctgatttg ttttaagatt tcttcattac
     8581 gctttactaa acgcgcaatt tttgcttccc tttcctccat ttctttctgt gcattattta
     8641 acgcaatttc tcgttttttt aaatctgctt ccttttggtc taagacattt tgggttgcac
     8701 tttgtaaggc ttgtaaggct tgttgttgct catcaattct ttcaatttct ttgatgattt
     8761 ctgctttgcg ttgctcaaag ataatattgc aatcaatgac ttcgcgttgg ttttcagctg
     8821 cccatattgg tagaattata agagctagtg tagataaaat ccattgtttc attgtttttc
     8881 cttgtggttt gcatatagca ttacagagat ttcgtctaaa tctctcattt cttgtttctt
     8941 tatttgttca agcctttttt tgacttccaa gccatctaaa tattttgctt tttcaaactc
     9001 aatattttgc cttttgaagt cttcttgtaa tttttgcctt tcgtgcttta gcaaagccaa
     9061 ttcttgaatt ttgaagtcaa tcatttgacg aaattcttct ttgtgatgca cgaaagttaa
     9121 gaagttttgg taaatcccat ttgttgggct ttgaagagtt gcaaattctt gcacaagcgt
     9181 atcaatttca ttttgtttta tgagaataac ttgtgcgttt ttttgtaaca tcatctcaat
     9241 ttcatctact ttctttttgt gtaagaggac aagttgagtg aattttgttt tcattggtga
     9301 ttccgattct atcgccctta tctaaagatt gtatcatttc tatctgggct tgtagagatc
     9361 attttaattt tcacgccaat aaacttttct agttctaaaa tatatttttg ggcattctgt
     9421 ggcagtttat caaattccct tattttttct gttttatccc aaccttgaaa agttttataa
     9481 ataggcttaa catttgttaa gttgctagga aattcctcta aacgcgttcc attttcattt
     9541 tcataagcaa tacaaacttt gatttgttca aatccgtcta gcacatctaa cttcatcata
     9601 gctaaggcat ttgcgccatt taggcgacaa gcatatttta ctgccatagc atctagccaa
     9661 ccgcaacgtc tagcgcgtcc tgttgttacg ccaaactccc ttcctttatt gcgcagactc
     9721 tcaccaatag agcctatttc ctctgttggg aaaggaccat tgccaacgcg tgtgcagtaa
     9781 gctttgataa tgccgataac ttctcctagc tcacgaggag caatccctgt cccattacaa
     9841 gctccagcag atattgtagt ggagcttgtt acaaaaggat aagttccaaa gtcaatatct
     9901 agcatacttc cttgcgcacc ttcacataga atctttttgc cctcgtccat tgctcgccaa
     9961 agcatatttg tggtattggt cagaagcggt aaaagcactt ttgcataatg gtctaattct
    10021 tgttttagac tttctaatgt tggaatttct attggaatcc ctttttttgc gatatcctct
    10081 agcttttcta atattttttt agctagtgtc tctgtgtccc tcaattcttc tgcgcgaatg
    10141 cctctgcgcg agaccttgtc agtataagtt ggtccgattc ctttgcaggt tgttccaatc
    10201 gcttgtttgg cttgttcttc gctcaatcta tctagcgttt cgtgataagg caaaataaga
    10261 tgtgctttcg tactaataaa gagtcgtcct tgtaaattac catacatttc ttcaaattgt
    10321 tgcatttctt ctatgagtgc atttgggcta atgaccacac cattaccgat gatatttttg
    10381 cattgaggat ataaaattcc agatggaatt aaatgcaaag cgtatttttt acctcccact
    10441 acaatagtgt gtcccgcatt atgtccgcct tgataacgca caacataatc gtaatgttgt
    10501 gcaagtaaat ctaccatttt gccttttccc tcatcacccc attgtattcc aacaatcaaa
    10561 tctgctttac tcacaatcac tccttaaata aattgtatta aattatctgt ataaactcca
    10621 aatccacaag cgttttgttc caaaatctta tattctccac ctaaaattaa tgttgtatta
    10681 ttggcaaaga atctaaaaaa taaacccttg taataactca ttggcgcata atataatggc
    10741 gagacaatac aatgcgcata atgaatctct gatgccaaat tgtaaagctt ttctaactct
    10801 aactttaatt cacttggtaa attatatgtg gagtcttgta aaaattcctt taaggtttct
    10861 tgattataaa ctcttaaaag ttttgccatt aaaggatttg tattttctat tgctccaata
    10921 tcaatttttt caaaagctgt taatggaatc ctaaaaattt ctgcacaaat ttgcggaatc
    10981 ttaacatttg ctaattgcaa aaaagccttt atattttgga tatttgatga ttctgtaaag
    11041 tttgtgattc catttaagag ctgtaaagaa atttgaataa aaggcaaaat atcacaattt
    11101 tccaagtttt ctacaccgat ttgatgcact tcggttgtgg gataaataaa aattggctga
    11161 atgtaaaacc aacgcttact aatagtggct tctcgcaaat gtggcgcaag aaggcgaatc
    11221 gtgtcaatgg ttgaatcatt gcgcagtgca atctgatgat tgtattggtt attggtgcgc
    11281 acaacttcac gactatgtgt atccctttgg tgttttaaat aggcaaaagt tggtgttaca
    11341 atttcctcat aaccattttg atataagatt tcacttgcaa gactttctaa ttctctttta
    11401 aatttagcat ttttgccaaa atatagtttg caaccctgcg gtatttcatg gcttaaaatc
    11461 acaaaatatc cttataatcc ttgataaaaa tctctaaatt ccgcattgta acataaaatg
    11521 tatgaaactt tattttttat tttagattgt aatctttttg tgagttttta tttaaagaag
    11581 ttacttgggt ttaatttgtg tgagtgagat tgtggattgc gttgtttggt tttatcttat
    11641 tctataattt tgcaaaaatg aaattaaata gtgcaattta caaaacaaac ataaggatca
    11701 taaaattaaa tagtcatttt tatgtgcatt ttgctataat ttatagaata taaatcaaag
    11761 gagattctat ggcatttaag attaacacgc aagcttatca aatccgctat cctaaacctt
    11821 ctccaagcgc accaatcaat gatcccaagg aagaatctcc gataaaaaat acaatccaaa
    11881 caggcaaccc aacaactaag ccacaaataa aatttccttc tcataatttg ttggataaat
    11941 ataactccgc agggtcttat tataattttc aaaacatatt aaataatcag ctaggcataa
    12001 agaataacaa tcaaagcaat agcgatgatg aaggtaaaaa agccttattg gagaatttgc
    12061 aacagcaaag caacgccttt aatcacggaa tctctggtag tggagattct aagcttaatt
    12121 ggagtgatgc gctagggcag tatttggaat tagaggatag cgttttgcac aaaaagttac
    12181 aagatgagca aaacgaacaa gcccaaagtg attttctcaa tgagcttttg tggaatctta
    12241 aaaagaattt gcctttataa acacacttta tttattgtaa ataaacataa attccttttt
    12301 accttaaaat gctataattt ctcatttaat taaatgaaag gtgggtatga aacagcttac
    12361 aataggaatt ataggattag gcacggtggg tagtagtgtc gcaaaaattc tcaaagacaa
    12421 tcaagcttta attgctgcac gtgcaggtta tacaattcat attaagcagg gagttgtcaa
    12481 agatttatcc aaaagtcgcc aagtatttga ttttcctatt actaatgaga tagattctgt
    12541 tttaaacgat tcagaaattg atattattgt ggaattaacg ggtggtgtag atgagccttt
    12601 tgagattgcc aaaaaggctt tacgcaattc taaggcattt gtaaccgcca ataaagctat
    12661 gcttgcttat caccgctatg aattgcaaaa aattgcagga gatttgccga ttggttttga
    12721 agcgagtgtt gcaggtggaa tcccaatcat caaagcgttg cgtgatggat tgggggcaaa
    12781 tcatatttta agcattcgtg gaattatcaa tggcacttgt aattttattt tgactaaaat
    12841 gaaagaacaa ggtgtagaat atgaagaagt tttgcaagaa gcgcaggatt tgggttatgc
    12901 tgaagctgac ccaacctttg atgtgggtgg ctttgatgcg gcgcataaat tattgatttt
    12961 agctagtatt gcgtatggaa ttgatgcaaa accagaagat gttttaattg aggggattac
    13021 gcaaatcacg caagaggata ttgcttttgc aaaagagttt ggttatcact taaagttgct
    13081 tggaatcgca agaaaagatg gggaagagat agaattacgt gtgcatccaa cgctattacc
    13141 taaagatgcg atgattggaa aagtggatgg tgtaatgaat gccattagtg tcgtgggaga
    13201 ttgtgtggga gagacgcttt attatggtgc aggtgcgggc ggaaatgcaa ctgcaagtgc
    13261 tgtaatttcg gatattattg aaattgcccg cacgaaaagc tctcctatgc ttgggtttaa
    13321 aaacatcagt aatacattgc gtttaaaacc gctagataaa attgttagtg cgtattattt
    13381 gcgtatttta gtgcttgata aaccgggtgt gttggcaaaa attgccacaa tttttggaga
    13441 agttggaatc tctattgata cttttttgca acgcaaagca aaagataagg cacattccac
    13501 tttgttgctt tctacacata cttgcacgga ggcggagatc aaaattgcct taaagcgcat
    13561 tagtgattta gagattgttt gtgccgctcc cgtgatgatt cgcattgaaa aataactttt
    13621 tggattcctt ttggggtaaa aaaataaaat cgcccaaaga ttctaaagaa tctccaatgc
    13681 aaaaattgta taatacaacg caaaagggca gggaagcgga ggattgtgcg tgtgaatttt
    13741 tgatagagca aggatttgtg gtgttagaga ggaattttca tacgcgtttt ggtgaattag
    13801 atattattgc taaaaaagat ggaatcttgc attttgttga ggtaaaaagc ggtatcggtt
    13861 ttgagccggt gtataattta agtccagcca aactcaaaaa gcttaccaaa actttaaata
    13921 tttatttaga aaaacaccac attcaggatt cctattgtct tagtgcattg attttatcca
    13981 agcaaagcgc aaatgatatt tttcaggtac attggctaga gaatttgaca atattttaat
    14041 actttttgtc cttacagctc taattttctg cctttgcgag acaaagccga agcaatccat
    14101 aatctagcat aaattaattt ttgcaatgga atccttaaag aagttgcatt attatagatt
    14161 gccacgattc tactaacgca gaatctcgca atgacaaagt ggaaaccact gtgtcattgg
    14221 gataaagccg aagcaatcca taatctagca tacattaatt tttgcaatgg aatccttaaa
    14281 gaagttgcat tattatagat tgccacgatt ctactaacgc agaatctcgc aatgacaaag
    14341 tggagacttt caagtatgca gagtatgcag gattatagat ttgcgctgaa gtgagtgcaa
    14401 atactacaca tttgcatacc acgacttcct acgaagtctc gcaatgacaa agtgggaagg
    14461 ttcataatga cagcagagta atcttgcgat gacgaggcgg taagtattcc tcgtatataa
    14521 aatcataaat agtaaaatca ccacactcat attaatattt ttcaaataaa atttattttg
    14581 tagtgctttt taagccaaaa aaggataaat ttactttaat ctaaattctt aaaaaggaag
    14641 agaatggaaa aagaacaaac actactccga caagcagaag agagactagc aaaactcgct
    14701 aagtttccag cactcaaaaa aggtgatagc attaaaaaaa tgctaaaaga aaaaggaatc
    14761 tcaagacgag attttatgaa atgggcgggg gcgatgacag cgatgttatc actaccggcg
    14821 agtttcacgc cacttactgc aaaggcggca gaagtcgcag accgcctacc tgtgatttgg
    14881 ctacatttag cagaatgcac aggttgtagc gaaagcctat taagaagcga tggaccgggt
    14941 attgcgagtt tgatttttga ctatatttcc ttagaatacc acgaaaccat tatggcggct
    15001 tctggttacc aagcagagga aaatttggaa tccgcaatag aaagatataa agggcgatat
    15061 gtcttaatgg tagaaggtgg tgtgccaaca ggactagatg ggcagtattt gacgattggc
    15121 gcgtttgggc atacagggtt gcaaaatgca aaaacagcaa gcgaaaatgc agcggcaatt
    15181 tttgcgattg ggacttgctc aagctttggt ggaatccaag ctgcaaaccc aaatccaact
    15241 gcagcaaagc cactaagtgc ggttacaaat aagccggtga ttaatgttcc gggctgtcct
    15301 ccaagcgaga aaaatatcgt aggcaatgtg attcatttct tgctttttgg aactctaccg
    15361 caacttgacg ctttcaatcg cccaaaatgg gcttatggtt taagaatcca cgatttgtgc
    15421 gagagacgcg gacattttga tgcgggtgaa tttgtgcaaa cctttggcga tgagggggca
    15481 aaaaatggct actgcctcta taaagttggt tgcaaaggcc cctacacttt caacaactgc
    15541 tccaaactcc gctttaattc ccatacgagt tggcctatcc aagcaggaca cggctgtatt
    15601 ggttgtagtg agccaaattt ctgggataca atgggacctt ttgaagaacc ccttgcaaac
    15661 aagctttatg atacgccttt ctttggcggg gcagaccgca ccgcagataa tattggaatc
    15721 acactgcttg gtgcagcggc aatcggtatg gcggcacacg cagtgctaag tgcggtgaga
    15781 aaagacaaag aataaggaga atttatgaca aaacgaatca ttgtagatcc tatcacaagg
    15841 attgagggac atttaagaat tgaagtgatt gttgatgaga acaatgtcat tacagatgct
    15901 tattctagct ctactttatg gcgtggaata gaggtgattg taaagaatcg tgaccctaga
    15961 gatgtagggt ttatggtgca aaga
//
