LOCUS       c00078_NZ_JABZ..       14743 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JABZSJ010000049.1 MAG: Prevotella aurantiaca isolate
            JCVI_44_bin.5 NODE_585_length_20490_cov_137.422657, whole genome
            shotgun sequence.
ACCESSION   c00078_NZ_JABZ..
VERSION     c00078_NZ_JABZ..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:02:41
            Original ID  :: NZ_JABZSJ010000049.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5747
            Orig. end    :: 20490
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14743
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[15747:19314](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13567
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..14743
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14743
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(571..1065)
                     /locus_tag="ctg78_11"
                     /transl_table=11
                     /translation="MMKKLSLLLLGLTLSLGIHAQFQEGKGYIGASLTGLDLHYNSRNK
                     FNIGLEAKLGYLAWDNTMLLATISAEHNGSETVADHFMLGVGGRYYISQNGLYLGVGCK
                     FLHANRSYNDLLVGTEVGYAFFINRSVTIEPALYYDHSFKDTSYSTVGLKIGLGIYLFD
                     D"
     CDS             1219..2916
                     /locus_tag="ctg78_12"
                     /transl_table=11
                     /translation="MNKKIITLLLLNWFFINCFAQTNDIFIKWDTTPFKKRETRAVWLT
                     TFSNLDWPSSLANSEEGIERQKQELIDILDKYVAANINTVLLQARVRAATIYPSKFEPW
                     DKCLTGRENGNPNYDPLAFAVEECHKRGLEIHAWVAAMPVGAAKSLGCRLMKQKGFNIK
                     SFSSGSYVSPEDQNIAGYLGEICAEITQNYDIDGINLDYIRYPDGWPHPTYRNGDTPEA
                     RRENITKIVREINRRVKVLKPWVKISCSPIGKYDDLSRYSSKNYNAKNRVSQDAQLWVK
                     TRIMDQLYPMQYWRDENYYPFCADWMENSNGHDIISGLGTYFLDPREGNMTLKELRQQM
                     YVSRWLGMGHAHFRSKFLLDNLQGIYNFEKRFNAIPSIPPALTWMNSRKPEAPKFFQGN
                     SVVALISAQGAKTISWKGTSPYYNIYMSNSYPVDINDPRNLVMARFQGTSFVHQGAKHQ
                     YYAITAMDRFGNESVALQSVLDKEGFKSRLLINDGKKITLPANINAMDIDYFCIESLQG
                     NVIMKIYYVASNRKTLNIYSLKNGTYKLCAHSAKRKISHEIGYFFIKR"
     CDS             complement(3013..3510)
                     /locus_tag="ctg78_13"
                     /transl_table=11
                     /translation="MAHRSLDQLDKKILRLIAEDARIPFLEVARECKVSGAAIHQRIQK
                     LTNLGILKGSQFIIDPEKIGYETCAYMGLNLKNPEKFDEVVEALKKIPEIVECHFTTGE
                     YDLFIKLYAQNNHHLLNIIHSKLQTLGLSRSVSLISYNAVIDRPLPINDFPVEENSESI
                     ED"
     CDS             complement(3984..5321)
                     /locus_tag="ctg78_14"
                     /transl_table=11
                     /translation="MVVFVPFVVPGDIVDLQVLKKRHSYCEATVVNVIAPSPIRIDPKC
                     KHFGICGGCKWQNLPYNEQLAAKQQQVIDQLTRIGKIDLPKVSPILGSEKTEEYRNKLE
                     FACSNKRWYTKEELEALPQNVGLAQGAIGFHITGAFDKIYPIEKCVLMDDYCNKVRNAI
                     FNYALSHNLTFFDIKEQRGLLRDVMMRNSNTGEWLVLVQFHYDEPGDEELAIGLMQFIA
                     DEFKEITSLLYVDNQKGNDTFNDLELIVFKGNDHIFELMEDLRFKVGAKSFYQTNTDQA
                     YHLYCVARNFANLTGNELVYDLYTGTGTIANFVAKNAKKVIGIEYVPEAIDDAKINSEI
                     NNIVNTIFYAGDMKDILTEDFVKIHGKPDVIITDPPRAGMHADVINVILGAHPQRIVYV
                     SCNPATQARDLSLLDNDYRVVEVQPVDMFPHTPHVENVVLLEARVR"
     CDS             5943..7058
                     /locus_tag="ctg78_15"
                     /transl_table=11
                     /translation="MKKLFMLAGLALALSNASAQTAKWINNVKLSGYGIAQYQFVSQDN
                     AKSNSFNLRLGRVSLDGRIFDDWAWKAQIQFNGNTSTLGSSPRVVDLFTEWQKYTFFRV
                     KIGQFKNPFTFENPIHPITQGFMGYSQVVSKFAGFADRAGTHSSNGRDIGIQFQGDFLK
                     NAAGRELLHYQVGVFNGQGINVKDVDEQKNIIGGIWVMPVAGMRIGCFGWTGSYARKGT
                     WTDAAGITQTGVRKLQQRRYAISAEYIVNDWTFRSEYAHSTGDAFAKTFINTNDAASKD
                     CSLSSNGDKAQGIYAAIIAPVIKKKLYAKARYDMYQPSKGTEKQRTLYEVGLNYEFNKN
                     VLLTSEYAYVHDRSLAKPNYSLVDLQLSFKF"
     CDS             complement(7325..8488)
                     /locus_tag="ctg78_16"
                     /transl_table=11
                     /translation="VLIKLKADFLCTCQPYNSHVILIEYRMILHIFNPEHDMSLAHNSS
                     NYTPSRAALRIRNDLAFLPYIWAKQGDAILVNNKKKAIDAINKLKFKKKEIVFVDVATL
                     STITEKIETVIPWGWDCTIKEQLKRLGVSQKILPTDDYLARICNLSNRKTAVHLLSILK
                     SFLSAKSVIGESYYIDNLADLYIKSKSLGNAVIKAPWSGSGRGLRFTDKEISTVHLNWA
                     KNIIAYQNGIILEPYYNKVQDFAMEFYLEDNKVNYCGLSIFSSLHGAYTGSLIDSEEKK
                     RNLLGQYIESELLDTIKGCLMYLLNQNIKDKYKGPLGIDMMIVGSRCSFEHSTSQHYYI
                     HPLVEVNFRRTMGHVALSLYNEMQIQNKVMQITFNGLYHTLEINDDI"
     CDS             complement(8473..8655)
                     /locus_tag="ctg78_17"
                     /transl_table=11
                     /translation="MAKYTFRNMQPMTFLTCKVTNYFLNLQTIDCKNDIFTIIYILSSY
                     IFVVSLHKNRLCSLS"
     CDS             8694..9878
                     /locus_tag="ctg78_18"
                     /transl_table=11
                     /translation="MDAFFRTHAYLVEHNHAPVRRMLMDEVNWDDRLIGIKGTRGVGKT
                     TFLLQYAKENFGANDRQCLYINMNNFYFQERGIADFAGDFYKGGGKVLLIDQVFKQPNW
                     SCDLRKCHDNYPELKIVFTGSSVMRLKEENPELNGIVKSYNLRGFSFREFLNYMTGHNF
                     PTYTLDEIIRNHEQIAMQILPKVSPLKYFQDYIHHGYYPFFLENRNYSENLLKTMNMMT
                     EVDILLIKQIELKYLTKIKTLFYLLALEGPKSPNISNLAKEINTSRATVMNYIKYLSDS
                     RLINIIYPVGQEFPKKPAKVIMNNSNLIYAIYPIHVEQQNVMETFFVNTLLSGHLVNEG
                     NKQGNYIIDENKKFKICDAENTKLRLNNETIYVRYNTEVGKDNKIPLWMFGFLY"
     CDS             10001..13567
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_19"
                     /sec_met_domain="PFOR_II (E-value: 1.9e-18, bitscore: 57.1,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2.2e-80, bitscore: 260.0,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.7e-31, bitscore: 100.0,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.6e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.3e-11, bitscore: 35.0,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.2e-05, bitscore: 15.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 2.2e-18, bitscore: 56.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKEKKYITCDGNEAAAHVSYMFSEVAAIYPITPSSPMAEHVDTW
                     SAKGRKNLFGQTVTVQEMQSEGGAAGAMHGSLQAGALTTTFTASQGLLLMIPNMYKIAG
                     EMLPCVFDVSARTIATHSLCIFGDHSDVMACRQTGFAMFCSGSVQEVMDLTAVPHLASL
                     KTSIPFVNFFDGFRTSHEYQKIEMIDQDEVAKLLDLEDVKRFRDRALSPERPVTRGTAE
                     NPETFFTHREACNQYYENIPEIVEDYLVKIKNITGREYHLFSYYGAEDAENIIILMGSA
                     TEAAREAIDYQMKQGNKIGMISVHLYRPFSVKHLLAAVPKTVKRIAVLDRTKEPGAEGE
                     PLYLDVKSAFYDVENKPLIVGGRYGLGSSDTTPAHIISVFNNLELAEPKNHFTVGIVDD
                     VTFTSLPLIDEIPMGGEGIFEAKFYGLGADGTVGANKNSVKIIGDNTNKHCQAYFSYDS
                     KKSGGFTCSHLRFGDSEIRSTYQVNTPNFVACHVQAYLRMYDVIRGLQKNGTFLLNTIF
                     EREELANFIPNKIKRYFAQNNITVYYINATKIAQEIGLGNRTNTILQSAFFRITEVIPV
                     DLAVEQMKEFIVKSYGNKGQDVVDKNYAAVDRGGEYKSLYVDPDWANLADDEDDANDDA
                     PAYIKEIVRPINGQVGDLLKVSDFIKYDMVDGTMKNGSSAFEKRGVEAFHPEWTSENCI
                     QCNKCAYVCPHACIRPFVLDEEEVKGFEDKTLEMKVPKPMAGMNFRIQVSILDCVGCGN
                     CVDVCPGNKQGKALAMIPFERDQKQIDNWNYLIKNVKTKQHLVDIKSNVKNSQFAQPLF
                     EFSGACAGCGETPYVKLISQLFGDREMISNATGCSSIYSASIPSTPYTTNEYGQGPAFD
                     NSLFEDFCEFGLGMALGNKKMRERITKLLSDALAEQHVSEDFKIAAQTWIDAKDDADAS
                     KEASAALKPMIAACAEAGCPICKELKTLDHYLVKRSQWIIGGDGASYDIGYGGLDHVIA
                     SGEDVNILVLDTEVYSNTGGQSSKSTPLGAIAQFAAQGKRIRKKDLGLMATTYGYVYVA
                     QIAMGADQAQTLKAIREAEAYPGPSLIIAYSPCINHGLKAKGGMGKSQAEEGRAVESGY
                     WHLWRYNPVLAEEGKNPFSLDSKEPDWNKFQDFLMGEVRYLSVKKAYPNEAQELFDAAE
                     QMAKLRYQSYIRKSKEDWSENI"
     CDS             14116..14742
                     /locus_tag="ctg78_20"
                     /transl_table=11
                     /translation="LYVQTKERISCCLCCGARSVVKNRYRLRDFVRLPIGGKRVTIRMK
                     VQRYKCKECDFDQQENIPFATGSRSYTHRFAKYVVDLLRVMTLQDVSHHLGVLWDMVKE
                     IHSSYLERHYSLPSLDKVENIGIDEFAVKKGHVYKTIVVDLNSGKIIYVGHGKGTKALK
                     KFWQKVKRKNIKIKHMATDLSAAFIASVMENCPDAVHVFDHFHVVK"
ORIGIN
        1 caattcatca ccaaccgata tgccacgagc aatcactgtt agctttatat caaagccttt
       61 aagcttacgt gatatataaa agtttgtggt atcaccttct atagtacttg ctaaagcaag
      121 aataatttca ttaactgtgc cagtttttac tcgttccaca agcgaatcta tttctaagtc
      181 gtttggtcca atgccatcta ttggtgaaat tattcctcct aacacatggt ataagccatt
      241 atattgttgg gtattttcaa tagcaagaac atcttgtacg ttttcaacaa cacataatat
      301 tgaagtatct ctatttggat ttacacaaat agagcattta tcagagtcgg aaatattgtg
      361 acaaatattg cagtatttaa tatcatgccg cattgtagaa attgctttag tgaagctatc
      421 gacatcttct ttagtttcac gtaataaatg taaagcatac cggagagcag tttttctacc
      481 tactcccggt aatttagaaa attctccaac ggccttttcg agcagttgag aaggaaattg
      541 ctgcatatca aacttgtcgt ttatacaggc ttaatcgtca aatagatata taccaagacc
      601 aatcttaaga cctacagttg aataactcgt atctttgaac gaatgatcat aatagagtgc
      661 tggttctatt gttacagaac gattaataaa gaaagcataa ccaacttcag taccgactaa
      721 aagatcatta taactacgat tggcatgtaa gaacttacat ccaacgccta aatataaacc
      781 attttgagaa atgtagtagc gtcctccaac acctaacata aaatggtctg cgacagtttc
      841 tgaaccatta tgttcagcac ttatagttgc caacagcatc gtattgtccc atgctaaata
      901 accaagcttt gcttctagtc ctatattaaa tttattgcga ctattataat gtaaatctaa
      961 tcctgttagt gaagctccta tgtagccttt accttcttga aattgtgcgt gaattcccaa
     1021 cgataatgtt aagcctaata agaggagaga tagtttcttc atcataattt ttattgttat
     1081 aaatataaag tttgtttatt attaaatttc aatgacaaag gtagtagaat tatttgaatt
     1141 acaaaaatta ttgcctatct ttgtggtcaa tttagaattg gcttctctcc tatttgtcaa
     1201 aaatatgctt taaaaagtat gaataagaag ataattacac tgttattatt aaattggttt
     1261 tttattaact gttttgcaca aacaaacgat atatttataa aatgggatac aactcctttt
     1321 aagaagcgtg agactcgtgc tgtttggcta acaactttta gtaatcttga ttggccctca
     1381 tcattggcaa actcagaaga aggcatcgaa agacaaaaac aagaacttat tgatatcttg
     1441 gataagtatg ttgcagcaaa cataaacaca gtattattgc aagcacgtgt acgtgctgct
     1501 actatttatc cgtcgaagtt cgagccttgg gataaatgtt taacaggtag agaaaatgga
     1561 aatccaaatt acgacccttt ggcatttgcc gttgaagaat gtcataaacg tgggttagaa
     1621 atccatgctt gggttgctgc tatgcctgtt ggtgcagcaa aatcattagg atgtagactt
     1681 atgaagcaga aaggatttaa tattaaaagt ttctcttctg gttcttatgt aagtccagaa
     1741 gaccaaaata ttgctggtta tttaggggaa atttgtgcag aaattactca aaattatgat
     1801 atagatggaa taaacttaga ctatataaga tatcccgatg gatggccaca tccaacttat
     1861 agaaatggtg atactcctga ggcgcgtcga gaaaatatta ctaaaattgt tagagaaatt
     1921 aatcgaagag taaaagtact aaaaccttgg gttaaaatat catgttcacc tataggcaaa
     1981 tacgatgacc taagcagata ttcgtctaaa aattataatg ctaagaatcg tgtttcacag
     2041 gatgcacaat tatgggtaaa gacaagaata atggatcagc tctatcctat gcaatattgg
     2101 cgtgatgaaa attattatcc attctgtgct gattggatgg aaaattcaaa tggacacgat
     2161 attatttcgg ggcttggaac ttactttctt gatccacgag aaggaaatat gacgcttaaa
     2221 gaacttagac aacaaatgta tgttagtaga tggttgggaa tgggacatgc tcatttccgt
     2281 tctaaattcc tattagataa cttacaaggt atttataatt ttgagaaacg ttttaatgct
     2341 ataccatcta ttccgcctgc tttaacttgg atgaatagca gaaagcctga ggcccccaag
     2401 ttttttcaag gtaattctgt tgtagcattg ataagtgcac aaggagcaaa aacgataagt
     2461 tggaaaggaa cttcacctta ttataatata tacatgagta atagctaccc cgtagatatc
     2521 aacgacccgc gtaatcttgt tatggcaaga tttcaaggaa cttcatttgt acaccaagga
     2581 gctaaacacc agtattatgc tattacagca atggatagat ttggaaatga aagtgttgca
     2641 ttacaaagtg tacttgataa agaaggtttt aaaagtagat tactgataaa tgatggtaaa
     2701 aaaattaccc tcccagctaa tataaacgca atggatatag actatttttg tattgaatcg
     2761 ttgcaaggca atgtaattat gaaaatatat tatgttgctt ctaatcgtaa aaccttaaat
     2821 atctatagtc taaaaaatgg aacttacaag ctttgcgcac attcggcaaa gcgcaaaata
     2881 agtcatgaaa ttggctattt ctttataaag cgataggtaa aaataattca agcactttcc
     2941 ttccaataaa acaaaaattt gttataactt tttgtttatg gtgaaagtgc ttgaattata
     3001 aattattaat ccttaatctt caatagattc agaattttct tccacaggaa aatcatttat
     3061 tggaagtggg cggtctatta ctgcattgta tgagataaga cttacacttc gtgataatcc
     3121 caatgtttgg agcttactat ggataatgtt taaaagatga tgattgtttt gagcataaag
     3181 cttgataaat aaatcatatt cgcctgttgt gaaatgacat tccacaattt cagggatttt
     3241 cttcaaagct tctactactt catcaaattt ctcagggttc tttaaattca atcccatata
     3301 cgcacaggtt tcataaccta ttttttctgg gtcaataata aattgtgaac ctttgagtat
     3361 acccaagttt gtcagttttt gaattctttg gtgaattgct gcaccactta ccttacactc
     3421 gcgtgcaact tccaagaatg gaatacgcgc atcttcagcg ataaggcgta aaatcttttt
     3481 gtctaattga tctaaacttc tatgtgccat ttatcttaaa aatttgccgc aaagttacaa
     3541 taatcttctt aaatcaccaa ttactttttc ataacaagtt ataattcata attttttcta
     3601 tcataaaata acacctttta aattttagat gttaatagta aaatttaaat gaatccctct
     3661 tatccataag ataagaaaga agcaataata ttcattatct ttttcttaaa tttactagtt
     3721 ttataactcg ctttacatca atattttaca aaaaatattt ttttcgatac aaagaagggc
     3781 ttttagaatt ataaaagtgc ctattttgaa atgcaaaaca gacactttta gaatctcaaa
     3841 atacagttat tgttttttaa cgaaatattt ttgcaaaaat aatagtattt ttatgtcttt
     3901 gtctttataa agtatctaaa aattatcatt tctaagaaaa ataacatcta tattagcttt
     3961 tttcgagttt tatcaaacac catttacctt actcttgctt ccaatagtac gacattttca
     4021 acatgaggtg tatgaggaaa catatcaaca ggctgaactt caacaactct atagtcatta
     4081 tctaaaagtg ataaatcgcg tgcctgtgtt gcaggattgc aactcacata gacaatacgt
     4141 tggggatgtg cacctaaaat aacatttata acatcagcgt gcataccagc gcgaggaggg
     4201 tcagttataa taacatcagg tttaccatgt atttttacaa agtcttctgt cagaatatct
     4261 ttcatatcgc cagcataaaa tatagtattg acaatattat taatctctga atttattttg
     4321 gcatcatcaa tcgcttcagg cacatattct ataccaatta ccttctttgc atttttggca
     4381 acaaagtttg ctattgttcc agtacctgta tataggtcgt aaactaattc gttccctgtg
     4441 agatttgcaa agtttcgtgc tacacaatat aagtggtaag cttggtctgt gtttgtttga
     4501 taaaaactct tcgctcccac tttaaaacga aggtcttcca ttagttcgaa aatatggtcg
     4561 ttgcctttaa atactatcaa ttctaaatcg ttgaatgtat cattaccctt ttgattatca
     4621 acatataata acgaggttat ttctttaaat tcatcagcta taaattgcat taggcctatt
     4681 gcaagttctt catctccagg ttcatcgtaa tgaaactgga ccaatactaa ccattcgcca
     4741 gtatttgagt ttctcatcat aacatcacgt aacaagccac gttgttcttt gatatcgaag
     4801 aaagtaagat tatgtgataa agcataattg aaaatggcat ttctcacctt attacaatag
     4861 tcgtccatca atacgcattt ttcaataggg taaattttat cgaatgcgcc agttatgtgg
     4921 aaacctatag ccccttgagc taaacctaca ttttggggta atgcctctaa ttcttctttg
     4981 gtataccaac gcttattaga gcaagcaaat tccaacttat tacgatattc ttcggttttc
     5041 tcagaaccta aaataggaga aacttttggt aagtcaatct ttcctattcg tgtaagttgg
     5101 tcaattactt gctgttgttt ggcagctaat tgttcattat aaggtagatt ctgccactta
     5161 caacctccgc agataccgaa atgtttgcat ttaggatcaa tacgaattgg acttggtgct
     5221 atcacattta ctactgtagc ttcacaatag ctatgacgct tcttaagaac ttgtaaatct
     5281 acaatatctc ctggtactac aaaaggaacg aaaacaacca tgtcatttac gtgtgctaca
     5341 catttccctt ccgctgcaac agcttctatt ttaacctttt ctaatatagg taatggtttt
     5401 ctttttctgc tcattttctt ttatttgcag caaagttagt tatttttttt attttgaact
     5461 gcaccttgat ttaaaagtag tacaaattcg atgtaagaaa gttgagtaaa aatttcggaa
     5521 ataaatattt aagatgacat tttaattgtt atctgcttat gtttaactaa aatacaaaat
     5581 gaatttctaa taattcaaca agtaaataat atctctcaat ctaaataata attacgaata
     5641 gataaattta taattacaaa attgaaattt ataattacgt ttttaaattt tataattata
     5701 aatttaagtg ctacctctat aaatcaataa gactagaaaa tatattaaga atactgaata
     5761 tataatataa aatgtaattt ggtaaaagta acaaaagtag ctgctcataa ataaaaattt
     5821 attgtatgat tatgctttta gatggctttt tgtcaaaaaa gttaagaatt gtttttaatt
     5881 cctataaaat atcagtacct ttgccacata aaactttaat cttaaaataa taacagggat
     5941 ttatgaaaaa gttatttatg ttggcaggtt tggcattggc actttctaat gcatctgcac
     6001 agacggcaaa atggattaat aatgtgaagc tatctggtta tggcattgca caatatcaat
     6061 ttgttagcca agataacgca aaatcaaatt cgttcaactt acgtttaggt cgtgtttctc
     6121 ttgatggacg tatttttgac gattgggctt ggaaagcaca aatccagttc aatggaaaca
     6181 catctacttt aggttcatca ccacgtgttg ttgatttgtt cacagaatgg caaaagtaca
     6241 ccttcttccg tgtgaagatt ggtcagttca aaaacccatt tacatttgaa aatccaatac
     6301 atccaattac acaagggttt atgggatatt cacaagtagt aagtaaattt gcaggatttg
     6361 cagatagagc tggtacgcat agttcaaatg gtcgtgatat tggtatacaa tttcaaggtg
     6421 atttcttaaa gaatgctgca ggtagagaat tgcttcatta tcaagttggt gtttttaatg
     6481 gacaaggcat taatgtaaaa gatgttgacg aacagaagaa catcattggt ggtatatggg
     6541 taatgccagt agcaggtatg cgtattggtt gttttggttg gacaggctca tatgctcgta
     6601 aaggaacatg gaccgatgca gctggtataa cacaaactgg tgttcgcaag ttacagcaac
     6661 gtcgttatgc aatctctgca gaatacattg tgaatgattg gaccttccga tcagaatatg
     6721 cacacagcac aggtgatgca tttgcaaaaa catttataaa tacaaatgat gcagcatcaa
     6781 aagattgcag tcttagtagc aatggtgata aagcacaagg tatttacgct gccattatag
     6841 cacctgttat aaagaaaaaa ctatatgcta aagcacgcta cgatatgtat cagccttcaa
     6901 aaggaactga aaaacaacgt accttgtatg aagtaggttt gaattatgaa tttaataaaa
     6961 atgtactact tacgagtgaa tatgcttatg ttcatgatcg cagtttagct aaaccaaact
     7021 attcattagt agacttacaa ttaagtttca aattttaaat aaaataatat aatacatgga
     7081 ggagacattg tgttaaatgt ttccttcatg taatcatatt ttctgcaaaa attaatggga
     7141 aaaagacaag tggataacaa aagtaaacat cgatacgatc agtatacagg atttaatcaa
     7201 caaagatatt cttcatctct tcgtaaaaga aaactaatat cgcgaattat tttatttttt
     7261 gtatgcgcaa tagctttagt tattacgcta tttgtatttt taatgtatgc aaaaataatt
     7321 tagtttatat atcatcattt atttctaatg tatggtataa accattaaat gtaatttgca
     7381 taaccttgtt ttgtatctgc atttcattgt atagggacaa agcaacatgc cccatagtac
     7441 ggcgaaaatt tacttctaca agtggatgaa tataataatg ttgagaagtt gaatgttcaa
     7501 aagaacatct acttccaact atcatcatat caattcctaa cggaccttta tatttgtcct
     7561 taatattttg atttaataga tacattagac atcctttaat tgtatctaat aactcacttt
     7621 ctatatactg tcctaatagg ttgcgcttct tctcttcgct atcaattaaa cttcctgtat
     7681 aagcaccatg caaagaggag aaaattgaaa gaccgcaata gttcacttta ttgtcttcta
     7741 aataaaattc catcgcaaag tcttgcactt tattataata tggctctaag ataataccat
     7801 tttggtaagc aataatattt tttgcccaat ttaaatgaac agtagatatt tctttatcgg
     7861 taaatcgtag ccctctccca ctaccactcc acggagcttt tatcacagca tttcctaaac
     7921 ttttactttt tatgtacaaa tctgcaagat tatcaatata gtaagattcg ccaataacag
     7981 actttgctga taaaaaggac ttcagaatag aaagtaaatg aaccgcagtt tttctattac
     8041 tcaggttaca tatccttgct aagtaatcat ctgtaggaag aatcttttga gatactccaa
     8101 gtcgttttaa ttgttctttt attgtacaat cccaccccca tggtataaca gtttctattt
     8161 tctctgttat ggttgataaa gtagctacat caacaaaaac tatttctttt tttttaaatt
     8221 taagcttatt gatggcatct attgcctttt ttttattatt taccaaaata gcatcgcctt
     8281 gttttgccca tatatatggt aagaaagcca agtcgttacg tattcttaat gcagcacgtg
     8341 aaggggtgta attagaacta ttatgtgcta atgacatatc gtgctcaggg ttgaaaatat
     8401 ggagtatcat tctgtattct atcaatataa catggctatt gtatggctgg catgtgcaaa
     8461 gaaaatctgc ctttaactta atgagcacaa cctattctta tgcaaagata caacaaagat
     8521 ataagaagac aaaatataaa taatagtaaa aatatcgttt ttgcaatcta tagtttgcaa
     8581 atttaagaaa taattagtaa ctttgcacgt gagaaatgtc attggttgca tgtttctaaa
     8641 agtatatttt gccatcgaca ttttcttagt atgaaataat ttagcaaatt aagatggacg
     8701 catttttccg tactcacgct tacttagtag agcataatca tgcaccagta cgccgtatgc
     8761 ttatggacga agttaattgg gatgaccgac taataggcat taagggaacg cgaggggtag
     8821 gaaaaacaac ttttcttctt caatatgcga aagaaaattt tggtgcgaat gaccgtcaat
     8881 gcctttatat aaatatgaat aacttctatt tccaggaaag aggaattgca gattttgctg
     8941 gagattttta taaaggtggt ggaaaggttt tactcataga ccaagttttt aagcagccta
     9001 attggagttg cgatttgaga aagtgccatg ataactatcc tgaattaaag attgttttta
     9061 cagggtcaag cgttatgcgt ctcaaagaag aaaatcctga actaaacggt attgttaaaa
     9121 gttataattt aagaggattt tcgtttagag agttcctaaa ttatatgaca gggcataatt
     9181 tcccgactta tactcttgat gagattatta gaaaccacga acaaattgca atgcaaattc
     9241 taccaaaggt tagtccgcta aaatactttc aagattatat tcatcatggt tattatcctt
     9301 tctttttaga aaacagaaat tattctgaaa acttactaaa aacaatgaac atgatgactg
     9361 aagttgatat attgttgatt aaacaaatag aactgaagta tctcacgaaa attaaaacac
     9421 ttttctattt acttgcacta gaaggtccaa agtcccctaa tataagtaat ttggcaaaag
     9481 aaattaacac aagccgtgca actgttatga actatattaa gtatttatca gattcacggt
     9541 tgataaatat tatctatcct gttggacaag aatttcctaa aaagccagca aaggtaataa
     9601 tgaacaattc taatctcatt tacgcaattt acccaataca cgtagaacaa caaaatgtaa
     9661 tggaaacttt ctttgttaat acgctattgt caggacattt ggtaaatgaa ggaaataaac
     9721 aaggaaatta cataatagac gaaaataaga aattcaagat ttgtgatgcg gagaatacaa
     9781 agttacgttt aaataacgaa actatctacg ttcgctataa tacagaagtt gggaaagata
     9841 ataaaatacc actctggatg tttggatttc tttattaaga cagatgttaa aaataaaaat
     9901 acgagactcc aaaaaaaata taatataaat atattgatca aaaacaggcc tatacaaaac
     9961 agcccaaaaa cattatagaa tcatttaata aataaagaaa atggcgaaag aaaaaaagta
    10021 tattacctgt gatggtaatg aagccgcagc tcatgtgagc tacatgtttt cagaggtagc
    10081 agctatctat ccgattactc cgtcatctcc aatggcagag catgtggata catggtcagc
    10141 aaagggacgt aagaatctct tcggtcagac agtaacagtt caggaaatgc aatcagaagg
    10201 tggtgcagct ggtgctatgc acggttcact ccaagctggt gcacttacaa caacattcac
    10261 agcttcacaa ggtttgttgt tgatgattcc taatatgtat aagattgcag gtgaaatgct
    10321 tccttgtgtg ttcgacgttt cagctcgtac aatcgctaca cactcattgt gtatctttgg
    10381 tgaccactca gacgttatgg cttgtcgtca gacaggtttt gcaatgttct gctctggatc
    10441 agtgcaagaa gtaatggacc ttacagcagt tccacatctt gcttcattga agacaagtat
    10501 tccatttgtt aacttctttg atggattccg tacatctcac gaatatcaga agatagagat
    10561 gatcgaccaa gacgaagttg caaaattact tgatctagaa gatgttaaac gtttccgtga
    10621 tcgtgcactt tctcctgagc gtcctgttac tcgtggtact gctgagaatc cagaaacatt
    10681 cttcacacat cgtgaagctt gtaaccagta ttacgaaaat attccagaaa tagttgaaga
    10741 ttacttggtt aagataaaga atattactgg tcgtgaatac catctattct cttactatgg
    10801 tgctgaagat gcagaaaaca tcattatcct tatgggttct gctaccgaag cagctcgcga
    10861 agctatcgac tatcaaatga agcaaggcaa caagattggt atgatttcag ttcaccttta
    10921 tcgtccattc tctgttaagc atttgctcgc agcagttcca aagactgtaa aacgtattgc
    10981 tgtacttgac agaacgaaag aaccaggtgc agaaggcgaa ccattatacc ttgatgttaa
    11041 gagcgctttc tacgatgttg aaaataaacc tctgatagtt ggtggccgtt atggtcttgg
    11101 ttcatctgat accacaccag ctcatatcat ttctgttttc aacaaccttg aactcgctga
    11161 acctaagaat cactttacag tgggtattgt agatgatgtt acatttactt ctcttccctt
    11221 gattgacgaa attccaatgg gtggcgaagg tatattcgaa gctaagttct atggtttggg
    11281 agctgatggt actgtcggtg caaataagaa ctctgttaag attataggtg acaacacaaa
    11341 taaacactgc caagcatatt tctcttatga ctctaagaag tctggtggtt ttacatgctc
    11401 tcaccttcgt ttcggagaca gcgaaattcg ttctacttat caggtaaata cacctaactt
    11461 cgtagcatgc catgttcagg catatttacg tatgtatgac gtaattcgtg gtttacagaa
    11521 gaatggtact tttcttttga ataccatttt cgaaagagaa gaacttgcaa acttcattcc
    11581 taacaagatt aagcgttact tcgctcaaaa caatattacc gtttactaca tcaacgcaac
    11641 aaagattgca caggaaattg gtcttggcaa ccgtaccaat actattcttc agagtgcatt
    11701 cttccgtatt acagaagtaa tccctgttga tttggcggtt gagcagatga aggaattcat
    11761 tgttaagtct tacggcaata agggacaaga cgtggttgat aagaactatg cagctgtaga
    11821 ccgcggtggc gaatacaagt cattgtatgt agatcctgat tgggctaacc ttgcagacga
    11881 tgaggatgat gcaaatgacg atgctcctgc atatataaag gaaattgttc gtcctatcaa
    11941 tggtcaggtt ggtgacttac ttaaggtttc tgacttcatc aagtacgata tggtagacgg
    12001 aactatgaag aatggatctt ctgcatttga gaaacgtgga gttgaagctt tccatcctga
    12061 atggacttct gagaactgta ttcagtgtaa caagtgtgct tatgtttgtc ctcacgcttg
    12121 tatccgtcca tttgttctcg atgaagaaga agtaaagggc tttgaagata agacattaga
    12181 gatgaaagtt ccaaagccta tggccggtat gaacttccgt attcaggtta gcatactcga
    12241 ttgtgtaggt tgtggaaact gtgttgatgt ttgtccagga aacaagcagg gtaaggcact
    12301 tgcaatgatt ccttttgagc gcgatcaaaa acaaattgat aattggaact acctcataaa
    12361 gaacgtcaag actaaacaac atttggtaga tatcaaaagc aacgtaaaga attcacagtt
    12421 tgctcaacca ttgtttgagt tctctggagc ttgtgcaggt tgtggtgaaa caccttacgt
    12481 taagttgatt tctcagttgt tcggtgaccg tgaaatgata tctaatgcta caggttgttc
    12541 ttctatttat tctgcgtcta tcccttcaac tccttataca accaacgagt atggtcaagg
    12601 tcctgctttc gataactcat tgtttgagga cttctgcgaa tttggtttgg gtatggcact
    12661 tggtaacaag aaaatgcgtg agcgcattac caagcttttg agcgatgcat tagcagaaca
    12721 acatgtatct gaagatttta agattgctgc tcaaacttgg attgatgcta aggatgatgc
    12781 cgatgcttct aaggaagcga gtgccgcgtt aaagccgatg attgctgctt gtgctgaagc
    12841 aggttgccca atttgcaaag aattaaagac tttagatcac tacttagtaa agcgttcaca
    12901 atggattatt ggtggtgatg gtgcttctta cgacatcggt tatggtggtc tcgatcatgt
    12961 aatcgcttct ggcgaagatg ttaatattct cgtacttgat acagaggttt attctaatac
    13021 aggtggtcaa agttctaagt ctaccccact tggtgctatt gcacaatttg ctgcacaagg
    13081 caagcgtatc cgcaaaaaag accttggctt gatggcaacc acctatggtt atgtttatgt
    13141 tgcacaaata gctatgggtg ctgatcaggc acagactctt aaggctattc gtgaggctga
    13201 agcatatcct ggtccatcgc tcatcattgc ttattctcca tgtatcaacc acggtttgaa
    13261 ggctaaggga ggtatgggta agagtcaggc tgaagaaggt cgtgcagtag aaagcggcta
    13321 ctggcactta tggcgttaca acccagtatt ggcagaagaa ggaaagaatc cattctctct
    13381 cgactctaaa gagccagatt ggaataagtt tcaagacttc ttgatgggcg aagtacgcta
    13441 tctctcagtt aaaaaggctt atcctaatga agctcaagaa cttttcgatg ctgctgaaca
    13501 aatggcgaaa ctccgttacc aaagctatat tcgcaagagt aaagaagact ggagcgaaaa
    13561 tatttagtcg ttccttaaaa actatatttc agcataaagc ttgtattgac aagctttatg
    13621 ctgattcttt atataaggta taaaagaact ctcatagctc ttttgaagtt ttatgctgct
    13681 gcagctaata atacattggt agcatctcct ttgtcacctt tataaaagtt gcgagataat
    13741 cggtggtctt ctttaatatt tcctatcgtt ggctctatac cagctcgttt acaagcctgg
    13801 cttatatgac aaaagtgtgc ttattttaga gtcgttctct tttatgtgac aaaaatgtgc
    13861 ttaaaaagtt ccattcccct tttatttctt aggggaatgg gactttataa agtcttgaat
    13921 gaatatcttt cttctggttc atcggggatt tggagtgata aaacagataa aataaaaaag
    13981 aaaccgctgt aaatattgta tatttgaata aacacaacca aatgtacaaa gatgaacagc
    14041 agtttcctat atcatgcttg gggtctttac acccacgaat gcacttgtga agaatacaaa
    14101 ggtaatagaa ttattttgta tgtacaaaca aaagagcgaa taagctgttg cctttgttgt
    14161 ggggctcgct ctgttgtgaa gaacaggtat cgcctgcggg actttgttag acttcccata
    14221 ggtggcaaac gagtaactat ccgcatgaag gtgcaacgct ataaatgtaa ggaatgtgat
    14281 ttcgatcagc aggagaatat tccctttgct actggcagtc gcagctatac tcatcgcttt
    14341 gccaagtatg tagtagattt acttcgtgtt atgacgcttc aggatgtatc gcatcatctg
    14401 ggtgtgttat gggatatggt aaaggaaata cactcctctt accttgagcg tcattatagc
    14461 cttccatctc tggataaggt ggagaatata ggtatagatg agtttgcagt taaaaaagga
    14521 catgtttata agaccatcgt cgtggatttg aacagtggca agataatcta tgttggccat
    14581 ggaaagggta cgaaagctct gaaaaaattc tggcagaaag tcaaacgtaa gaatataaag
    14641 ataaaacata tggcaacaga cctgtctgcg gctttcatag cctctgtcat ggagaattgt
    14701 cccgatgcag tacatgtgtt tgatcatttc catgtagtga agt
//
