LOCUS       c00047_NZ_JAGZ..       22538 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAGZTV010000029.1 MAG: Klebsiella sp. isolate
            L2_037_016G1_dasL2_037_016G1_concoct_2 L2_037_016G1_scaffold_62,
            whole genome shotgun sequence.
ACCESSION   c00047_NZ_JAGZ..
VERSION     c00047_NZ_JAGZ..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:28:45
            Original ID  :: NZ_JAGZTV010000029.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 75101
            Orig. end    :: 97639
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22538
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[85101:93902]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..18801
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..22538
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22538
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="2"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(335..1075)
                     /locus_tag="ctg47_66"
                     /transl_table=11
                     /translation="MPQSLLEYIKGRLNAEAPAPLYIQLKQAIEAAMTERLLTHGSILP
                     SERKMSQTLELSRVTVVKALDALLEAGLVIKRHGKGTEVNLPVSYNLASGGFSAQLQNS
                     GTVSNRWLVREKLAADDFLARELEIAVGDRVAKIKRVRLVDALPVSIETMFIPERFLPR
                     PDLLEGSLYAHWAENDIYPDLQDYSLTVHIPSAEELNLLDLPQGVPLMKITLKSRNAQG
                     EVLEYGTAFCLSNYFNFDFRVKLQ"
     CDS             1296..2312
                     /locus_tag="ctg47_67"
                     /transl_table=11
                     /translation="MSDIRPTYTTESRILGCLYGQAIGDAMGMPSELWPKRRIINHFGW
                     IERFLPGPKENIAACEFRAAEFTDDTHQCIALMDALNETNGVTDPLVIARHILLWARRC
                     QAFEKNILGPTSKASLIALEQGQPLEEIAANGVTNGAAMRVAPMGCLLPTGDRTFFIEQ
                     VRLSCLPTHKSDIAIAGAVVIAWAIGRAIEGAEWPLIKTELASLANETQRHYESTFSPL
                     LGNRIHLALETIAGETDHLTGIERIYEDIGAGMDIIESVPAAIALVELAKTQPMKCAML
                     AANLGGDTDTIGAMATAICGALHGIEAFPEEHIQRIKQANSIDFAPYAQRLAGYRFA"
     CDS             2331..3746
                     /locus_tag="ctg47_68"
                     /transl_table=11
                     /translation="MDSKASYDGNIQATDPGMAELGIGLVPPVHQTQKPVQLFFVWCAA
                     NIGILGVVYGAVIVSFGLSFWQAILAAVAGVASFALVGITSIAGKIGRTTTLTLSRVIF
                     GKRGNIAPTSFCWVNLMGWEAVNIITGTLTLVALFAAMGFEESLTTTALSLFLFGGLTV
                     LVSVLGQNAVLMMQKWITRIFGAMTLLVVIYLLFTADWQAILALPSGSWLTGFLPAVSI
                     IAAGTGISWAIAGADYSRDQRPDSGEKPIFLAVVSGAALPLLLLMLTGILLTAQIPDLA
                     SSENPISAIGKLLPSWMAIPYLAAATAGVVTIAVLSLYSASLNLLSMGIKLQQRSAVAL
                     DAVLVLGIALYVLFVSKDFLGPFIAFLIFCGVFLAAWAAIFMVDFYRLRRRAGYPEADL
                     FRESGANRTALGCWIVGALAGLMVSKTGFIDGPFAVGIFADSSLGLFVSFILSLALYLA
                     FGMRKGACRDNQR"
     CDS             3730..4692
                     /locus_tag="ctg47_69"
                     /transl_table=11
                     /translation="VTISADLLSPQRPIVVIGAAFGDIILHLDALPQSGGDISARDGGR
                     QIGGCAFNVARALSRLELFPINAIPIGNGDWGQAVAQKMALENLPVLLRHPTHDNGWCL
                     ALVEASKERTFITIEGCEQHWTDELLAQIPLPKEAIIYVSGYELASEALRQWILAQTED
                     KTLFVDFGPRLCDLDIHFIQALLRKRPLLTLNRDELSVLCARLYDLDSATLDAASRLAS
                     DWHIRAICRFDKDGAWVVEPDTAPQHIPACRVKVHDTIAAGDSHCAGTIAGLACGMDLQ
                     QATRLGNQVAAIVVSQPGSDGAPDRKALRQFQIQQQNSR"
     CDS             complement(4696..6792)
                     /locus_tag="ctg47_70"
                     /transl_table=11
                     /translation="MGSLLLSVPLFLLQSPPRSKIEQKTPMRLNPGQQQAVEFVTGPCL
                     VLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVGQTLGRKEARG
                     LMISTFHTLGLDIIKREYAALGMKSNFSLFDDTDQVALLKELTEGLIEDDKVVLQQLIS
                     TISNWKNDLKTPVQAAAGAKGERDRIFAHCYGLYDAHMKACNVLDFDDLILLPTLLLQR
                     NEEVRERWQNKIRYLLVDEYQDTNTSQYELVKLLVGQRARFTVVGDDDQSIYSWRGARP
                     QNLVLLSQDFPALQVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGVELKV
                     LSANNEDHEAERVAGELIAHHFINKTAYKDYAILYRGNHQSRVFEKMLMQNRIPYKISG
                     GTSFFSRPEIKDLLAYLRVLTNPDDDSAFMRIVNTPKREIGSATLKKLGEWAMGRNKSM
                     FTASFDMGLTQTLNGRGYESLTRFTHWLREIQQLSEREPIAAVRDLIRGVDYESWLYET
                     SPSPKAAEMRMKNVNTLFTWMTEMLEGSEIDEPMTLTQVVTRFTLRDMMERGESDEETD
                     QVQLMTLHASKGLEFPYVYLVGMEEGLLPHQSSIDEDNVDEERRLAYVGITRAQKELTF
                     TLCKERRQYGELVRPEPSRFLLELPQDDLIWEQERKVISPEERMHKGQANVANIRAMLA
                     KARK"
     CDS             complement(6817..7545)
                     /locus_tag="ctg47_71"
                     /transl_table=11
                     /translation="MDFFSINNVMVNIPLGEGGYALSWIEAIGTVFGLLCIWCASREKI
                     INYLFGLINVTLFAAIFFQIQLYASLLLQVFFFAANIYGWYAWSRQNEAQEAALKVRWL
                     SRQQTLALGGVCAVAIVLMTLFIDPVFATLTRIMIALLQTFGMQVAMPDLQPDAFPFWD
                     STMLVLSIAAMVLMTRKFVENWLLWVVIDVISVVIYAVQGVYAMSLEYVLLTAIAVMGS
                     YSWIKSAQRNGYTPLAAAAS"
     CDS             complement(7545..8294)
                     /locus_tag="ctg47_72"
                     /transl_table=11
                     /translation="MSLQPHIQLSKEMTGARYALLPGDPQRVDRIVNFLDNPQLLGQNR
                     EFRAARGWYQGIEILVLSTGIGGPSTAIAIEELRQIGVTTLIRIGSCGALQDNLAFGDV
                     IIAHAAVMDDGTSRTYAPAGYPACADPLLTWELVAQARQMNIPAACGLVRSHDSFYTDR
                     EAELDAQWSARGVLGADMESAALMTIGALRGLRTASLLNVVVAHNGCLDSSINDYVQQE
                     ALCQQGEERQITLALRAIYSASQQGGL"
     CDS             complement(8319..9023)
                     /locus_tag="ctg47_73"
                     /transl_table=11
                     /translation="MDTMKKPEFSVGWLSGLSEIVRDPLLYELLKYCPLEIMRRWRFED
                     IPRGDFICRQGEVCQRFSLIIAGEVDVFYEAEDGRRYRQARYRKGDMVGELEIFESRHY
                     ICSVVAVDHVQLLSLSQEHFCRWLALDNHFNQRMLRFFSQQYYQLSKKASSDNLYSLHQ
                     RVCQALWLRYQQDGANEILLDKQNLSQEFAATTRSINRILHDLKALQIIDTDGERIVLL
                     APEKLKQEADIG"
     CDS             9218..9499
                     /locus_tag="ctg47_74"
                     /transl_table=11
                     /translation="MAKSAAALHILVKEEKLAQEILAKLERGVSFDHLAKRYSKCPSGR
                     NGGDLGEFNQGVMVGPFDKAVFSCPLLKPYGPVKTKFGYHIIKVLYRR"
     CDS             9552..9833
                     /locus_tag="ctg47_75"
                     /transl_table=11
                     /translation="MAKTAAALHILVKEEQLALDLLEQIKNGADFGKLAKKHSICPSGK
                     RGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRN"
     CDS             complement(10001..11476)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_76"
                     /sec_met_domain="IlvN (E-value: 7.3e-61, bitscore: 197.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 6.2e-31, bitscore: 100.1,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGC
                     GAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVN
                     LTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVRE
                     EYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQ
                     TILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPA
                     KLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFE
                     TAPQFEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIAN
                     TIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKEFMTTLQTGDLGKAIAEGAVDNAQL
                     RDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG"
     CDS             11630..12520
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.8; E-value: 6.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg47_77"
                     /sec_met_domain="LysR_substrate (E-value: 7.8e-41,
                     bitscore: 132.1, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 9e-24, bitscore: 75.8,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEEDLGQ
                     PLFVRDNRTVTLTEAGEELRTFAQQTLLQYQQLRHTIDQQGPSLSGELHIFCSVTAAYS
                     HLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGEADLAIAGKPETLPGAVAFSMLEN
                     LAVVLIAPALPCPVRNQVSVEKPDWATVPFIMADQGPVRRRIELWFRRHKISNPSIYAT
                     VGGHEAMVSMVALGCGVALLPEVVLENSPEPVRNRVMILERSDEKTPFELGVCAPKKRL
                     HEPLINAFWNLLPGH"
     CDS             complement(12577..14121)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: Thr_dehydrat_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_78"
                     /sec_met_domain="PALP (E-value: 2e-80, bitscore: 262.8,
                     seeds: 146, tool: rule-based-clusters)"
                     /sec_met_domain="Thr_dehydrat_C (E-value: 3.2e-31,
                     bitscore: 99.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAESQPLSAAPEGAEYLRAVLRAPVYEAAQITPLQKMEKLSSRLD
                     NVVLVKREDRQPVHSFKLRGAYAMMAGLTEEQKSHGVITASAGNHAQGVAFSASRLGVK
                     ALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELAQQQGFTWVPPFDHPMVI
                     AGQGTLALELLQQDAHIDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSACLKA
                     ALDAGQPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIVTVDSDAICAAMKDLFEDV
                     RAVAEPSGALALAGMKKYIAQHNIRGERLAHVLSGANVNFHGLRYVSERCELGEQREAL
                     LAVTIPEEKGSFLKFCQLLGGRSVTEFNYRFADAKNACIFVGVRLSRGLEERKEILNLL
                     HDGGYSVVDLSDDEMAKLHVRYMVGGRPSQPLQERLFSFEFPESPGALLKFLHTLGTHW
                     NISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLHELGYDCHDESNNPAFRFFLAG"
     CDS             complement(14124..15974)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_79"
                     /sec_met_domain="ILVD_EDD (E-value: 2.5e-220, bitscore:
                     724.8, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKYRSATTTHGRNMAGARALWRATGMTDDDFGKPIIAVVNSFTQ
                     FVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSV
                     EYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLD
                     LVDAMIQGADPKVSDDQSNQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLL
                     ATHADRKQLFLNAGSRIVELTKRYYEQDDASALPRNIANKAAFENAMTLDIAMGGSTNT
                     VLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVLGILGELD
                     RAGLLNRDVKNVLGLSLPQTLEQYDITVTQDEAVKKMFRAGPAGIRTTQAFSQNCRWDT
                     LDDDRAEGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQ
                     DAAVDAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTTFLKSMGLGKACALITDGRFS
                     GGTSGLSIGHVSPEAASGGNIAIIEDGDMIAIDIPNRGIQLQLSDAEIAARREAQEARG
                     DKAWTPKDRERQVSFALRAYASLATSADKGAVRDKSKLGG"
     CDS             complement(16036..16965)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_80"
                     /sec_met_domain="Aminotran_4 (E-value: 3.7e-52, bitscore:
                     169.8, seeds: 70, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKADYIWFNGEMVPWGEAKVHVMSHALHYGTSVFEGIRCYDS
                     HKGPVVFRHREHMQRLHDSAKIYRFPVSQSVDELMEACREVIRKNSLTSAYIRPLVFVG
                     DVGMGVNPPPGYNTDVIIAAFPWGAYLGAEALDQGIDAMVSSWNRAAPNTIPTAAKAGG
                     NYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSALPGIT
                     RDAIIKLAKDLGLEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEGRCGPI
                     TKRIQQAFFGLFTGETEDKWGWLDQVNQ"
     CDS             complement(16982..17239)
                     /locus_tag="ctg47_81"
                     /transl_table=11
                     /translation="MMQHQVALQARSNPETLERVLRVVRHRGFQICAMNMATAADARNI
                     NIELTVASQRPVELLFSQLSKLVDVACVEIQQPTSQQIRA"
     CDS             complement(17236..18801)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_82"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.9e-52, bitscore:
                     167.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVYDALYDGGVEHLLCRHEQGAAMAAIGYARATGKTGVCIATSG
                     PGATNLITGLADALLDSVPVVAITGQVAAPFIGTDAFQEVDVLGLSLACTKHSFLVQSL
                     EELPRIIAEAFHVANSGRPGPVLVDIPKDIQLAQGDLDPHFSMVADDVDFPYADIEYAL
                     QMLTQSQKPMLYVGGGVGMAQAVPALREFLAVTQMPVTSTLKGLGAVAADYPYYLGMLG
                     MHGTKAANLAVQECDLLIAVGARFDDRVTGKLNTFAPHAKVIHMDIDPAELNKLRQAHI
                     GLTGDLNVLLPALQQPLSIDAWRQRNAQLRAEHAWRYDHPGDAIYAPLLLKQLSDRKPA
                     DCVVTTDVGQHQMWSAQHMTYTRPENFITSSGLGTMGFGLPAAVGAQVARPDDTVICIS
                     GDGSFMMNVQELGTVKRKQLPLKIVLLDNQRLGMVRQWQQLFFQERYSETTLTDNPDFL
                     TLASAFGIPGQHITRKDQVEAALDTMLSSQGPYLLHVSIDELENVWPLVPPGASNAEML
                     EKLS"
     CDS             19417..20937
                     /locus_tag="ctg47_83"
                     /transl_table=11
                     /translation="MSLAIVYTRAALGIGAPLITVEVHISNGLPGLTMVGLPETTVREA
                     RDRVRSAIINSGYAYPAKKITINLAPADLPKEGGRYDLPIALALLVASEQLKAPRLNQY
                     EFVGELALTGALRGVPGAISSAMEAIKAGRRIVVSNENSPEVGLIGGSDCLIATDLQEV
                     CAFLEGRHTLANPLPEGEYSDETSVDLRDVIGQRQGKRALEIIAAGGHNLLMIGPPGTG
                     KTMLASRLPGLLPPLSNQEALESAAILSLVDSRHAMKNWRRRPFRAPHHSASLAAMVGG
                     GSIPAPGEISLAHNGVLFLDELPEFERRVLDALREPIESGVIHISRTRAKIDYPARFQL
                     IAAMNPSPTGHYQGQHNRASPEQTLRYLGRLSGPFLDRFDLSLEIPLPPPGVLSQGTNE
                     EESSACVRQRVLAARERQLSRQKKLNAHLGNDEMKICCRLHKDDAVWLEQTLIQLGLSI
                     RAWQRLIKVSRTIADIEAVERIERHHLQEALGYRAIDRMLSHLQKMMA"
     CDS             complement(20961..21299)
                     /locus_tag="ctg47_84"
                     /transl_table=11
                     /translation="MAESFTTTNRFFDNKNYPRGFSRHGDFTIKEAQLLERHGYAFNEL
                     ELGKREPVTDDEKQFVSVCRGEREPATEAERVWIKYMARIKRPKRFHTLSGGKPQVEGT
                     EDYTESDD"
     CDS             21418..22239
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     71.9; E-value: 1e-22)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg47_85"
                     /sec_met_domain="LysR_substrate (E-value: 6.4e-15,
                     bitscore: 47.5, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.4e-22, bitscore: 71.9,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGV
                     NLFTRHRNNIRLTSAGEKLLPYAETLMNTWQAARKEVANASRHNEFSIGASASLWECLL
                     NGWLGKLYTEPYNLQFEARIAQRQSLVKQLHERQLDLLITTESPKMDELSSQLLGNFTL
                     ALYCASPAKYTNELNYLRLEWGPDFQQNEAGLIGNDDIPLLTTSSAELAYQQLSALKGC
                     TWLPVLWAQGKNNLHTVTDSATLSRPLYAIWLQNSDKQAQIREILKHNILG"
ORIGIN
        1 cattcatcaa caaaacgcgg tgcctccgag agtcgcggag catatgtgcc gtctgctgcg
       61 tctggcgatt ctgtttgcca gccgccgacg cgacgatctg ctgccgatgc taacgctggc
      121 tgccgaagat gaaaatttga cgttaacgct gccgaagggc tggctggaga atcatccgct
      181 gggccgggaa atggtcgaac aggagtgcca gtggcagagc tacgttcact ggccgctgcg
      241 gcttaacgag cagtagtcgg atatgatccg ctctcgcata aagcgatggc gggtttaata
      301 caccgaccat gccaaaataa ctggccgact gcgcttattg cagcttcact ctgaaatcaa
      361 aattaaagta attgctcagg cagaatgcgg ttccgtactc aagcacctct ccctgagcat
      421 tgcggctttt cagcgtaatt ttcatcaatg gcacgccttg cggcaggtcg agcaaattca
      481 gctcttccgc cgaaggaata tgcaccgtca gtgagtaatc ctgaagatcg ggataaatat
      541 cattttccgc ccagtgcgcg tacagcgaac cttcaagtag atccgggcgg ggtaagaaac
      601 gctcggggat aaacatggtt tcgatagaca ccgggagggc atcgaccaga cggacgcgtt
      661 tgattttcgc cacccgatcg ccgaccgcga tctccagctc acgggccaga aaatcatccg
      721 ccgccagctt ttccctcacc agccatcggt tggacaccgt gcctgaattt tgtagctggg
      781 cagaaaatcc gccgctggca aggttatagc ttaccggcag attcacctcg gtcccttttc
      841 cgtggcgttt aataaccagc ccggcctcca gcagcgcatc aagcgccttt acgaccgtca
      901 cgcgcgatag ctcaagcgtc tgcgacattt tgcgttcgga aggcaggatg ctgccgtgcg
      961 tcagcaaccg ctcggtcatt gccgcttcaa tagcttgttt aagttgaata taaagcggcg
     1021 cgggagcctc tgcattcaga cgccctttta tatactcaag cagcgattgc ggcataatgt
     1081 cgtagtcttc cggaattcag tggcagtgga tttatcatag tggatccata ctggaatcaa
     1141 tagccccctt ataacgtctc ccaccctttt ttagcttctc acttttcttt cataatgcgt
     1201 cttcgatcac agcatggcca caaaggactt taactggact taatctggat ctacttttag
     1261 tataactttt attcatttct tccagggagc cgatgatgtc tgatattcgc cctacctata
     1321 ccaccgaaag ccgcatcctc ggctgccttt atgggcaagc catcggtgat gcgatgggta
     1381 tgccttccga actgtggcct aagcgccgaa ttatcaacca ttttggctgg attgagcgct
     1441 tcctccccgg accgaaagag aatattgcgg cctgcgaatt tcgcgccgct gagttcaccg
     1501 atgataccca tcagtgcatc gcactcatgg atgccctgaa tgaaaccaac ggcgtgaccg
     1561 atccactggt catcgccagg catattctgc tgtgggccag acgctgtcag gcctttgaaa
     1621 aaaatattct tggcccgacc tcgaaggctt ccctgatcgc gcttgaacag gggcagccgc
     1681 tggaggagat cgcggccaac ggcgtaacca acggcgcggc aatgcgcgtg gcgccgatgg
     1741 gctgtctact gcccaccggg gacagaacgt ttttcattga gcaagtgcgg ctatcctgcc
     1801 tgccgacgca taaatcagac atcgctatcg ccggcgcggt ggtcattgca tgggcgatcg
     1861 gccgcgccat tgaaggggcc gaatggccgt taatcaaaac ggagctggcg tcgctcgcca
     1921 atgagacgca gcgccattat gagtccactt ttagtccact actgggaaac cgtatccacc
     1981 tggcgctgga aacgatcgcc ggggagactg accatctgac gggtattgaa cggatttatg
     2041 aggacatcgg cgccggtatg gatattatcg agtccgtccc cgcagcgatt gctctggttg
     2101 agctggcaaa aacgcagcct atgaaatgcg ctatgctggc agccaattta ggtggcgaca
     2161 ccgacactat tggcgcgatg gccaccgcca tctgcggcgc gcttcatggc atagaggctt
     2221 ttcctgaaga acatatacaa cggattaagc aggccaacag catcgacttc gcgccttacg
     2281 cacagcggct tgcaggctac cgcttcgcat aattcacaga gggtatcact atggacagca
     2341 aagcttcata cgatggaaat atccaggcga cagatcccgg aatggcagaa ttaggaatcg
     2401 gtctggtccc cccggtccac cagacccaga aaccggtcca gctgtttttc gtctggtgcg
     2461 ccgcgaatat tggcattctt ggcgtcgttt acggcgcggt gattgtgtcg ttcggcctct
     2521 cattctggca ggcgattctg gccgccgtgg cgggcgtcgc ctcctttgcg ctggtcggca
     2581 tcaccagcat cgccgggaaa attggtcgta cgacgacgct aaccctctcc cgcgtcattt
     2641 ttggcaaacg cggtaatatc gcccccacca gcttctgttg ggtgaatttg atgggctggg
     2701 aagcggtcaa tatcattacc ggcacgctca ccctcgtcgc gctgtttgcc gccatgggtt
     2761 ttgaagagag tctgaccacc accgcgctgt cgcttttctt gtttggcggg ctgaccgtac
     2821 tggtcagcgt gctcgggcaa aacgccgtgc tgatgatgca aaaatggatc acccggatct
     2881 ttggcgccat gacgctgctg gtggtgatct atttactctt caccgcggac tggcaggcca
     2941 tcctcgcgct gccttcaggc agctggctga ccggctttct gccggccgtg tctattattg
     3001 ccgcgggcac cggcatcagt tgggctatcg ccggcgccga ctatagccgc gatcagcgcc
     3061 ctgactccgg ggaaaaacct atttttctcg ccgtggtcag cggcgccgcc ctccccctgc
     3121 tgttgctgat gctcaccgga atactgctta ccgcgcagat ccccgatctg gcctccagcg
     3181 agaaccccat ttcagcgatc ggtaaactgc tgccttcgtg gatggcaatc ccctatctgg
     3241 ccgcggctac cgccggagtc gtgaccatcg ccgtgttgag cctctattcc gccagcctta
     3301 acctgttaag catggggatt aagctacagc agcgttccgc cgtggccctc gacgccgtgc
     3361 tggtgctggg gattgccctc tacgtgctgt ttgtctcgaa agattttctc gggccgttca
     3421 tcgcgttttt gattttctgc ggcgtatttc tggccgcctg ggccgccatc tttatggtcg
     3481 atttttatcg gctgcgccgc cgtgccggat atcctgaagc tgatttattc agggagagtg
     3541 gcgcaaaccg taccgcgctg ggctgctgga ttgtcggtgc gctggcagga ttgatggtct
     3601 ctaaaaccgg ttttatcgac ggacctttcg cggtcggtat tttcgcggac tccagcctcg
     3661 ggttattcgt ctcttttatt ctgagcctgg cgctgtatct cgccttcgga atgagaaagg
     3721 gggcctgccg tgacaatcag cgctgacctg ctatcgcctc agcggccgat cgtggttatc
     3781 ggcgccgctt ttggcgacat tattctccat ctcgatgcgc tgccgcaaag cggtggcgat
     3841 atctccgccc gcgacggcgg acggcagatt ggcggctgcg cgttcaacgt cgcccgcgcg
     3901 ctctcgcgcc tcgaactgtt tcccattaac gccataccga taggcaatgg cgactggggg
     3961 caggccgttg cgcaaaaaat ggcgctggaa aacttgcccg tcctcttgcg ccatcccacc
     4021 cacgataacg gctggtgtct ggctcttgtc gaagccagca aagagcggac gtttatcacc
     4081 attgagggct gcgaacagca ctggactgat gaactattag cgcaaatacc gctgccgaag
     4141 gaggcgatta tttacgtctc gggatacgaa ctggccagcg aagcgctgcg ccagtggatc
     4201 cttgcccaga cggaagataa aacgctgttc gtcgattttg gcccgcgtct gtgcgacctg
     4261 gatattcact ttatccaggc gctgctgcgc aaacgccccc tgctcaccct gaatcgcgat
     4321 gaactcagcg tgctttgcgc gcgtttatac gatttggata gcgcgaccct tgatgccgcc
     4381 tcacggctcg ccagcgactg gcatattcgg gcgatctgtc ggtttgataa ggatggcgca
     4441 tgggtggttg aacctgacac agcaccgcag catattccgg cctgccgcgt gaaggtccac
     4501 gacacgattg ccgcaggaga cagccactgt gccggtacga tcgccgggct ggcctgcggg
     4561 atggatctgc agcaggcaac gcggctgggc aatcaagtgg cggccattgt cgtcagtcaa
     4621 cccggttcag acggcgcacc cgatcgcaaa gcgctacgtc agttccagat tcaacagcaa
     4681 aacagccgct agccgctatt tacgcgcttt cgccagcatc gcccggatgt tggcgacgtt
     4741 cgcctggcct ttatgcatgc gctcttccgg cgaaatcact ttgcgctcct gctcccaaat
     4801 caggtcgtcc tgcggcagtt ccagcaggaa acggctcggc tccggtcgca ccagctcgcc
     4861 gtactgacgg cgctctttgc acagggtaaa agtcagctct ttctgcgcgc gagtgatacc
     4921 cacgtaggca agacggcgct cttcatcgac gttgtcttca tcaatgctgc tctggtgcgg
     4981 cagcagcccc tcttccatac caaccaggta gacgtagggg aactccagcc cctttgacgc
     5041 gtgaagcgtc atcagctgca cctgatccgt ctcctcatcc gactcgccgc gctccatcat
     5101 atcgcgcagg gtaaagcggg taacgacctg agtgagcgtc atcggttcat cgatctcgct
     5161 gccttcgagc atttcggtca tccacgtgaa cagcgtattg acgtttttca tccgcatttc
     5221 ggcggctttc gggctgggcg aggtctcata gagccaggat tcataatcca cgccgcggat
     5281 cagatcgcgg acggcggcaa tcggttcacg ctctgaaagc tgctggatct cccgcagcca
     5341 gtgggtaaag cgggtcaaag actcatagcc gcgtccgttc agggtctggg tcaggcccat
     5401 atcgaagctg gcggtaaaca tgcttttatt gcgccccatc gcccattcac ccagcttttt
     5461 cagcgtcgcc gaaccgattt cacgctttgg cgtattgacg atgcgcatga aagcgctgtc
     5521 atcatcggga ttagtcagca cgcgcagata ggccagcagg tctttaattt ccgggcggga
     5581 aaagaacgac gtgccgccgg aaattttgta cggaatgcgg ttttgcatca gcatcttttc
     5641 gaaaacccgc gactgatggt tgccacgata caggatcgcg tagtccttat aggcggtttt
     5701 attaataaag tgatgcgcga tgagttcacc ggcaacgcgc tccgcctcat ggtcttcgtt
     5761 attggcagag agcaccttca gctctacgcc atagcccagt tcggaaaaca gacgcttctc
     5821 gaaaacgtgt gggttattgg caatcaggat gttagccgcc ttcaggatgc gcccggaaga
     5881 acggtagttt tgctccagct tgatcacctg cagcgccggg aaatcctggc ttagcaggac
     5941 caggttctgc ggccgcgcgc cgcgccagga gtagatcgac tgatcgtcat cgccgaccac
     6001 ggtaaagcgc gcccgctgtc ccaccagcag tttcaccagc tcgtactggc tggtgttggt
     6061 atcctggtat tcatccacca gcagatagcg aatcttattc tgccagcgct cccgcacctc
     6121 ttcgttacgc tgcagcagca gggtcggcag caggatcaga tcatcgaagt cgagtacgtt
     6181 acaggctttc atatgcgcgt cgtacagccc gtagcagtga gcaaagatcc gatcccgctc
     6241 ccctttcgcg ccagcggcgg cctggacagg ggttttcaga tcgtttttcc agttggagat
     6301 cgtcgagatc agctgctgaa gcaccacttt atcgtcttcg atcagccctt cggtgagctc
     6361 ttttaacagc gccacctggt cggtatcgtc gaacagcgag aagtttgatt tcatccctaa
     6421 cgcggcgtat tcgcgtttga tgatatccag ccccagcgtg tggaaggtgg aaatcatcag
     6481 gccgcgcgcc tctttgcgtc ccagcgtttg cccgacgcgc tctttcattt cgcgcgccgc
     6541 cttgttggta aaggtgaccg ccgcgatatg acgcgcctga tagccgcagc cgcggatcag
     6601 gtgggcgatt ttattggtaa tcacgcgggt cttaccggaa ccggcacccg ccagcaccag
     6661 gcacggtccg gtaacgaatt cgacggcttg ttgttggcca ggatttaaac gcatgggagt
     6721 cttttgctca atcttcgaac ggggtgggga ttgtagcaga aagaggggca cagagagcaa
     6781 caggctgccc attcaggcag cctggaaatc ggtcaatcag gatgcggccg cggcaagcgg
     6841 cgtatagccg ttacgctgtg cgcttttgat ccagctgtat gagcccatta ccgcgatcgc
     6901 cgtcagcagg acatactcaa gcgacatggc gtaaacgccc tgtaccgcgt agataaccac
     6961 gctaatcacg tcgataacca cccacagcag ccagttttcg acgaatttac gcgtcatcag
     7021 caccatggcg gcaatcgaca acaccagcat ggtggaatcc cagaacggga aggcgtcggg
     7081 ctggaggtcg ggcatcgcga cctgcatacc gaacgtttgc agcagagcaa tcatgatacg
     7141 agtgagcgtc gcgaaaaccg gatcgataaa cagcgtcatc agcacaatcg ccaccgcgca
     7201 gacgccgccc agcgccagcg tttgctgacg ggaaagccag cgtaccttga gcgcggcctc
     7261 ctgcgcctcg ttttgccggc tccacgcgta ccagccgtaa atattggcag cgaagaaaaa
     7321 gacctgcagc agcaggctgg catagagctg gatctggaaa aagatcgccg caaacagcgt
     7381 gacgttaatc aggccaaaca gatagttgat gattttttcc cggctggcgc accagatgca
     7441 cagcaggccg aatacggtac cgatagcctc aatccacgat agcgcatagc cgccttcgcc
     7501 gaggggaatg ttgaccatca cattgttaat gctaaaaaag tccatcacaa acctccttgc
     7561 tggctagcgg aataaatggc gcgcagcgcc agggtaattt gccgttcttc gccctgctgg
     7621 cacagcgcct cctgctggac ataatcattg atgctgctat ccaggcaacc gttgtgggca
     7681 acaaccacgt tgagtaatga tgccgtacgt aggccgcgca gcgcgccgat agtcatcaga
     7741 gcggcgctct ccatatccgc gcccagaacg cctcgcgccg accactgcgc atccagttcc
     7801 gcctcacgat cggtatagaa actgtcgtgg ctgcgcacca gcccgcacgc ggcggggatg
     7861 ttcatttgcc gcgcctgcgc caccagttcc caggtcagca gcgggtcggc gcaggccgga
     7921 tagcccgccg gcgcataggt tcggctggta ccatcatcca tcaccgcagc gtgagcgata
     7981 atcacatcgc cgaacgcaag attatcctgc aatgcgccgc agctgccgat acgaatcagg
     8041 gttgttacgc caatctggcg cagttcttca atggcgatcg ccgtggaggg tccgccgatg
     8101 ccggtggaga gcaccaaaat ctcgatgccc tgataccagc cgcgcgcggc gcgaaactcc
     8161 cggttctgac cgagcagctg tggattatca agaaaattga cgatgcggtc gacccgctgc
     8221 gggtcgcccg gcagcagcgc gtaccgcgcg ccggtcatct ctttgcttaa ctggatatgg
     8281 ggttgcagcg acattctccc gcctccttac tcttgcggtt atccgatatc agcctcctgc
     8341 ttcagttttt caggagctaa caacacaatg cgttcaccat cggtatcaat aatctgtagc
     8401 gctttcagat catgcaaaat acggttaatg ctgcgggtcg tcgccgcgaa ctcctgactg
     8461 agattctgct tatccagcaa gatttcattc gcgccatcct gttgataacg cagccatagc
     8521 gcctgacaca cccgctgatg cagcgagtag agattgtcgc tgctggcctt tttcgacagc
     8581 tgataatatt gctggctaaa gaagcgcagc attcgctggt taaagtggtt atccagcgcc
     8641 agccagcggc agaaatgttc ctgcgacagg ctcaggagtt gcacatggtc caccgccacc
     8701 accgagcaga tgtaatgacg cgactcaaag atctcgagtt cgcccaccat gtcgccttta
     8761 cggtagcggg cctgacggta gcggcgcccg tcttcagcct catagaaaac gtccacctca
     8821 ccggcgataa tcagcgaaaa acgctggcac acttccccct gtcggcagat aaaatcaccg
     8881 cgcggaatgt cttcgaagcg ccagcgccgc atgatctcca gaggacaata tttcagtaat
     8941 tcatagagca gcggatcgcg cacaatctcg ctcagcccgg aaagccagcc gactgaaaat
     9001 tcaggttttt tcattgtatc catgttatct cgctccacga cgataaggac aggacggctg
     9061 tccccggcca gaaggaaaac gccgaagaaa agtgttgccc atctcccgct tccgtctatc
     9121 aggcgagaca cctgtcccgc gatggcgaag agtataggtc cgcgaccaaa gcggatggta
     9181 aagtaacggg atatctttga gacatgagag caaaataatg gcaaagagcg cagcagccct
     9241 gcatatcctg gttaaagaag agaagctggc gcaagagatc ctcgccaaac tggaacgtgg
     9301 cgtgagcttc gatcatctgg caaaacgcta ttcaaagtgc ccatccggac gcaacggcgg
     9361 cgatctcggg gagtttaatc aaggcgttat ggtcgggccg ttcgataagg cggtcttcag
     9421 ctgcccgctg ctaaagcctt acggaccggt caaaaccaaa ttcggctacc acatcattaa
     9481 ggtgctgtat cgccgctagc ccatgctact attgcgccct gattcatctc ctattccatc
     9541 aaggtacgat catggcaaaa acggcagcag cactgcatat cctggttaaa gaagagcagc
     9601 tggcactgga tcttctggag caaattaaaa acggcgccga tttcggtaaa ctggcgaaga
     9661 agcactcgat ctgcccgtca ggcaaacgcg gcggtgattt aggtgaattc cgccagggcc
     9721 agatggtgcc ggcgtttgat aaagtcgtct tctcctgccc ggtgctggag ccgaccggcc
     9781 cgctgcacac ccagtttggt tatcacatca tcaaggtgct gtaccgcaat taaaaaaacc
     9841 ggtgtcttat tgcaccggtt ttttatctca cagctttccc ctaagtattt cagcttgcag
     9901 gaaggcggca agtgagtaca gccccaggag catagataac tatgtgactg gggtgtacga
     9961 acgcagccaa cgcatctgca agttgaaaga cgacggggaa ttagcccgct accgcaatac
    10021 gcttcatatc ggtcatatag ccgcgcagtt tcttaccaac ctgctcaata gcgtggctgc
    10081 gaatggcttc gttcacgtcg cgcagctgag cgttgtctac cgcgccttcg gcaatcgctt
    10141 tgcccaggtc gccggtctgc agggtggtca tgaactcttt cagcagcggt acgcaagcgt
    10201 aagagaacag gtagttaccg tattcagcgg tatcggaaat aaccacgttc atttcgtaca
    10261 gacgcttacg agcgatggtg ttggcgatca gcggcagttc gtgcagtgat tcgtagtaag
    10321 cggactcttc gatgatgccg gaatccacca tggtttcaaa cgccagctca acgcccgctt
    10381 tcaccattgc gatcatcaga acgcctttat cgaagtactc ctgctcgcca attttacctt
    10441 caaactgcgg tgcggtttcg aacgcggttt tgccggtctc ttcccgccag gtcagcagtt
    10501 ttttatcgtc gttggcccag tcagccatca tgccggagga gaattcaccg gagatgatgt
    10561 catccatatg cttctggaac agcggcgcca taatctcttt cagctgttcg gacagcgcgt
    10621 aagcacgcag cttagccggg ttagacaggc gatccatcat cagagtgata ccaccctgct
    10681 tcagcgcttc ggtgatggtt tcccagccga actgaatcag tttttcggcg tatgccgggt
    10741 cggtaccctc ttccaccagc ttatcgaagc acagcagaga accggcctgc agcataccgc
    10801 agaggatggt ctgctcgccc atcaggtcgg atttcacttc ggcaacgaag gacgattcca
    10861 gcacgcccgc acggtgaccg ccggtcgccg cagcccaggc tttagcaatg gccataccct
    10921 cgcctttcgg atcgttttcc gggtgaaccg cgatcagggt cggtacgccg aagccgcgct
    10981 tgtactcttc acgcacttcg gtacccgggc acttcggcgc caccatcacg acggtgatat
    11041 ctttacggat ctgctcgcca acttccacga tgttgaagcc gtgagagtag cccagcgccg
    11101 cgccgtcttt catcagcggc tgaacggaac gtacaacgtc agagtgctgt ttgtccggcg
    11161 tcaggttaac caccagatcg gcctgcggga tcagctcttc gtaggtaccc accttgaagc
    11221 cgttttcggt tgctttgcgc catgatgcgc gcttttcggc aatcgcttct ttacgcagcg
    11281 cgtaggagat atccagaccg gagtcgcgca tgttcagacc ctggttcagg ccctgagcgc
    11341 cacagccgac aatgaccact tttttaccct gaaggtagct tgcgccatcg gcgaattcgt
    11401 cgcgacccat aaagcgacat ttgcccagct gcgccagctg ctggcgcagg ttcagtgtat
    11461 taaagtagtt agccatggtg atacctcgtg atgttgtgtg tcttattttg ttcggttcgc
    11521 ctttcagcga gaatgtaccc acattacaac aggaaattta ttgcggaaat tgatatattc
    11581 acaacgtcac gttgcaattt ctgcaatgta aaatcgtgga gtgccgccag tggatttacg
    11641 cgatctgaaa accttcctgc atctggctga aagccgccat tttggccgca gcgcgcgggc
    11701 gatgcacgtc agcccctcca cgctttcccg acaaattcag cgcctggaag aagacctcgg
    11761 gcagccgctg tttgtccgcg ataaccgcac ggtaacgctt accgaagcgg gagaagagct
    11821 acgaacgttt gcccagcaga cgctgttgca gtatcagcag ctgcgccaca ctatcgatca
    11881 gcaaggtccg tcgctgtcgg gcgaactgca tatcttctgt tcggtgacgg ccgcttatag
    11941 ccatctgccg ccgattctcg atcgtttccg cgccgagcat ccctcggtgg aaataaagct
    12001 caccaccggc gatgccgctg atgcgatgga gaaagtggtg acgggtgagg ccgatctggc
    12061 gattgcaggg aaaccggaaa cgctgcccgg cgcggtggct ttttccatgc tggagaatct
    12121 ggcggtggtg ctgatcgccc cggcgctgcc ttgtccggtt cgtaaccagg tctcagtcga
    12181 gaagcctgac tgggcaacgg taccctttat tatggccgac cagggccccg tgcgtcgccg
    12241 cattgagcta tggtttcgcc gccataaaat cagtaatccg tcaatttacg ccacggtggg
    12301 cgggcatgaa gccatggttt ccatggtggc gctcggctgc ggcgtcgcgc tgctgccgga
    12361 ggtggtgctg gaaaacagcc ctgagccagt gcgcaatcgc gtgatgattc tggagcgtag
    12421 cgacgagaaa accccgtttg agctgggcgt ctgcgcgcca aaaaagcggc tgcatgagcc
    12481 gctgattaat gcgttctgga atttgctgcc tggccactaa tgccgggcct gctcaggcct
    12541 acagcccggc cacaggcctg acaagcacag agcttcttaa ccggcgagga agaacctgaa
    12601 tgctggatta ttgctctcat catggcaatc gtagcccagc tcatgcaagc gggtttcgaa
    12661 gtcaggctcg tgatcgccta gttcgaatgc cgccagcacg cggccgtaat cggtaccgtg
    12721 gctgcgatag tggaacagag agatgttcca gtgggtgccc agcgtatgca ggaacttcag
    12781 cagcgcgccg ggcgactccg gaaactcgaa gctgaacaaa cgctcctgca gcggctgaga
    12841 cggacgcccg ccgaccatat agcgcacgtg tagcttggcc atttcatcgt cggagagatc
    12901 cactacgctg tagccaccgt cgtgtagcag gttgaggatc tctttccgct cttccagccc
    12961 ccggctcagg cgcacgccga caaaaatgca ggcatttttc gcatccgcga agcggtagtt
    13021 gaactcggtc accgaacggc cgcccagcag ctggcagaac ttgaggaagc tgcccttctc
    13081 ttccggaatc gtcaccgcca gcagcgcttc ccgctgttcc cccagctcgc agcgttcgga
    13141 aacgtagcgc aggccgtgga agttgacgtt cgcgccggaa agcacgtgcg ccaggcgttc
    13201 gccgcgaata ttatgctgag cgatatattt tttcatcccc gccagcgcca gcgccccgga
    13261 aggttctgct accgcacgca cgtcttcaaa caggtctttc atcgccgcgc agatggcatc
    13321 gctatcgacg gtaacgatgt cgtcgagata ctcctggcac agacggaaag tctcatcgcc
    13381 gatgcgtttc accgccacgc cttcggcaaa aagcccaacg cggggtaaat cgaccggttg
    13441 acccgcatcc agcgcggctt tcagacaggc agaatcctcg gcctcaaccg caatgacttt
    13501 gatctgcggc atcagctgtt tgatcagcac cgccacgccg gccgcgagac cgccaccacc
    13561 gaccgggaca aatacgcgat cgatatgggc atcctgctgc agcagttcca gcgccagcgt
    13621 cccctgcccg gcaatcacca tcggatggtc gaagggcgga acccaggtga acccctgctg
    13681 ctgcgccagt tcgatggctt tggccttggc ttcatcgaag ttcgcgccgt gcagcagcac
    13741 ttcgccgccg aagccgcgca ccgcatcgac tttgatatcc gcggtggcgg ttggcatgac
    13801 gatgagcgcc ttcacgccca ggcgagatgc cgagaaagcc acgccctgcg catgattacc
    13861 cgccgaagcg gtaatcacgc catgcgattt ttgctcttcc gtcaggcccg ccatcatcgc
    13921 gtaggctccg cgcagcttaa agctgtgcac cggctgacgg tcttcacgct tcaccagcac
    13981 aacgttatcg aggcgcgacg agagcttttc cattttttgc agcggcgtga tctgcgcggc
    14041 ttcgtatacc ggcgcgcgca gtaccgctct gaggtattcc gccccctcag gggcggcgga
    14101 caggggttga gactcggcca tcattaaccc ccaagtttcg atttatcgcg caccgcgcct
    14161 ttgtcggcgc tggttgccag gctggcatag gcgcgaaggg caaaggaaac ctgacgctcg
    14221 cggtctttcg gcgtccatgc tttatcaccg cgcgcttcct gagcttcgcg gcgcgccgca
    14281 atctcggcat cgcttagctg cagctgaata ccgcggttcg ggatatcgat agcaatcatg
    14341 tcgccatctt caatgatcgc gatattgcca ccgctggccg cttccggaga aacgtgacca
    14401 atagagagac ctgaagtacc gccggagaag cgtccgtcgg taatcagcgc acaggcttta
    14461 cccaggccca ttgatttcag gaaggtcgtc gggtagagca tctcctgcat ccccggcccg
    14521 cctttcggcc cttcatagcg gatgacgact acgtcaccgg cgaccacctt gccgccgagg
    14581 atcgcatcca cagccgcgtc ctggctttcg tataccttcg ccgggccggt aaatttgagg
    14641 atactgtcgt caacgccggc ggttttcacg atacagccgt tctcggcaaa gttgccgtac
    14701 agaaccgcca gaccgccgtc cttgctgtaa gcatgttcca gcgagcggat acagccttct
    14761 gcgcgatcgt catccagggt gtcccaacgg cagttctgag agaaagcctg cgttgtgcgg
    14821 atacccgcag ggccagcgcg gaacatcttc ttaaccgctt catcctgcgt gacggtgata
    14881 tcgtactgct ccagcgtctg cggcagggac aaaccaagca cgtttttcac atcgcggttc
    14941 agcagcccgg cacgatccag ttcacctaaa atacccaata cgccgcccgc gcgatgcacg
    15001 tcttccatat gatatttctg cgtacttggc gcgaccttac acagctgcgg cactttgcgg
    15061 gaaagtttat cgatatcgct catggtgaag tcgatttccg cttcctgcgc cgccgccagc
    15121 agatgcagta cggtattggt ggaaccgccc atggcgatat ccagcgtcat ggcgttttca
    15181 aacgccgcct tattggcgat attacgcggc agcgcagagg catcgtcctg ctcgtaatag
    15241 cgtttagtca gctcaacgat acgtgagccc gcattgagga acagctgttt acgatcggcg
    15301 tgagtcgcca gcagcgagcc gttgcccggc tgcgacaggc ccagcgcttc ggtcaggcag
    15361 ttcatggagt tcgcggtgaa cattcccgaa caagagccgc acgtcgggca ggcggaacgc
    15421 tcaacctgat tactctgatc gtcggagact ttcgggtcag cgccctgaat catcgcgtca
    15481 acgaggtcga gtttaatgat ttgatcggac agtttggttt tcccggcttc catcgggcca
    15541 ccggaaacaa aaatgaccgg aatattcagg cgcagagacg ccattaacat ccccggggtg
    15601 attttgtcgc agttggagat acagaccatc gcatcagcac agtgggcgtt aaccatatac
    15661 tcaaccgagt cggcgatcag ttcgcgggat ggcagtgaat aaagcatacc cccgtggccc
    15721 atcgcgatcc catcatccac cgcaatggtg ttgaattctt tggcgacgcc gccagcggct
    15781 tcgatttgct cagcaaccag tttgccaaga tcgcgcaggt gaacgtggcc cggcacgaac
    15841 tgggtgaaag agttcaccac ggcgataatc ggcttaccga aatcatcgtc ggtcattcca
    15901 gtggcgcgcc acagcgcgcg ggcacccgcc atattacggc cgtgagtggt tgtggcggaa
    15961 cggtacttag gcatgcttta gttactccca gtttcggtga aatggggcgt tgcgtgtcgc
    16021 cccatttttt tatgcttatt gattaacctg atccaaccag ccccatttat cctcggtttc
    16081 accggtgaag aggccaaaga atgcttgctg aatgcgcttg gtgatcgggc cgcagcggcc
    16141 ttcgcccacc tgaataccat caacgctgcg taccggcgtg atctctgcgg cagtaccgga
    16201 cataaacact tcgtcggcca ggtacaggga ctcgcgggac aatacctgct cgcggacttc
    16261 cagaccgaga tctttcgcca gcttgatgat agcgtcgcgg gtgatgccag gcagcgcgga
    16321 agaggtgaac ggcggggtaa acagcacgcc atccttcact tcaaacaggt tttcaccggc
    16381 gccttcagag atgtagccgt tcacgtccag cgcgatacct tcctgatagc catggcgacg
    16441 cgcttcgctg ccgaccagca gcgaagagag atagttacca ccggctttgg ccgcggtcgg
    16501 aatagtgttt ggtgccgcgc gattccagga agaaaccatc gcatcgatcc cctgatccag
    16561 cgcttcggca cccaggtagg cgccccacgg gaacgccgcg atgatcacgt cagtgttata
    16621 gcccggaggc gggttgacgc ccatgcctac gtcgccgacg aagactaacg ggcggatata
    16681 ggcgctggtc agactgtttt tacgaatgac ttcacggcag gcttccatca gctcatcaac
    16741 gctctgagaa accgggaaac gatagatttt tgctgagtca tgcaaacgtt gcatatgttc
    16801 acggtgacgg aacaccaccg gtcccttgtg agagtcgtag caacggatgc cttcaaatac
    16861 ggaagtcccg tagtgcagcg catgggacat cacgtgaacc ttcgcctcac cccacggaac
    16921 catctcacca ttgaaccaaa tgtaatcagc ttttttcgtc gtcattgttc ttcctttgcg
    16981 ctcaggcgcg aatttgttgt gatgtaggtt gctggatctc gacgcaggcg acgtccacca
    17041 gtttgcttaa ttgactaaac agtaattcga cgggccgctg gctggcaacg gtcagttcaa
    17101 tattaatatt ccgggcatcg gcggcggttg ccatattcat cgcgcaaatc tggaacccgc
    17161 gatggcgcac gacgcgcaac acgcgttcta atgtttctgg attagagcga gcctgcaagg
    17221 cgacctgatg ttgcatcatg ataatttctc cagcatttct gcattactgg caccgggcgg
    17281 caccaacggc cagacgttct caagttcgtc gattgagaca tgaagcaggt aaggcccctg
    17341 gctcgaaagc atggtgtcga gtgccgcttc aacctggtct ttacgggtga tgtgttgacc
    17401 agggatgccg aaggcgctgg ccagagtaag gaaatcgggg ttatcggtaa gggtggtttc
    17461 gctatagcgt tcctgaaaaa acagctgttg ccattgtcgg accattccta aacgctggtt
    17521 gtccagtaag actatcttca gcggcaactg cttgcgtttt acggtgccca gctcctgcac
    17581 gttcatcatg aaggagccgt caccggagat acagataacc gtatcgtctg gacgggccac
    17641 ctgcgcgcct accgctgcgg gcaagccgaa acccatagtg cctaatccgc tggaagtgat
    17701 aaaattctcc gggcgcgtat aggtcatatg ctgcgctgac cacatctgat gctggcccac
    17761 atcggttgtc acgacgcagt ccgcgggttt gcgatcggaa agctgcttca gcagcagcgg
    17821 ggcatagata gcgtctcccg gatggtcgta acgccaggca tgctcggcgc gcagctgtgc
    17881 attacgttgg cgccaggcgt cgatagacag cggctgctgg agcgcgggca gcaacacatt
    17941 caaatcgccg gtcaggccga tatgtgcctg acggagcttg ttcagttcag ccggatcgat
    18001 atccatatgg atgactttgg cgtgcggggc aaacgtattc agcttgccgg tgacgcgatc
    18061 gtcaaaccgg gcgcctaccg cgatcagcag gtcacattcc tgtactgcaa ggttggccgc
    18121 tttagtaccg tgcatcccca gcatgcccag atagtaggga taatccgccg ctaccgcacc
    18181 cagccctttc aaggtagacg tcacgggcat ttgcgtaacg gcaagaaatt cgcgcagcgc
    18241 cggtaccgcc tgcgccatcc ccacgccgcc gccaacgtat aacatcggct tctgcgactg
    18301 ggtcagcatc tgcaaagcgt attcgatatc cgcatatgga aaatcaacgt cgtcggctac
    18361 catggaaaaa tgcggatcga gatcgccctg agccagctgg atatcctttg ggatatcgac
    18421 cagcacggga ccgggacgcc cggagtttgc tacgtggaaa gcttcggcaa tgatgcgcgg
    18481 cagttcttcc agcgactgca ccaggaaact gtgcttggtg catgccagcg ataaaccgag
    18541 gacatcaact tcctggaatg cgtcggtgcc aatgaacggg gcagcaacct gaccggtgat
    18601 agcaacaacg ggaacggaat caagcagcgc gtcggcgagg ccggtgatca ggttggttgc
    18661 gccaggaccc gaagtggcga tacacacccc ggttttgccg gtagccctgg catagccgat
    18721 agccgccata gccgcgccct gttcatgccg acacagtagg tgttccacgc cgccgtcata
    18781 caatgcatcg taaaccggca taattgctcc acccggatag ccaaaaacgg tatcgactcc
    18841 ctgtgctcgc aaagcatgta ctacccaccg cgccccattc atagttactt ccccgtcgta
    18901 gatcgagaga aacagaattt tatgctgcca gccatcgtct gctcctcttt tctgttttta
    18961 agttataaaa aaacccccgg acctttcggt gcgggggtct tagttcgtta aggcttgttt
    19021 tttaagcctt tcctcgtcca agtgcagccc cgcacggtgg gatcatttta tgttctttct
    19081 ggcttcatgt tcgaaggaat acctaaagag gtaccacaga cttcgtgtta aacacaagat
    19141 ttttttatga cctcatttct taccttgcta accatttaag aaaaaacaat tgtttttaat
    19201 aggaaaaata tgaaatgaaa atatttcatt ttgtggcgta ctccacagca ctttctcatc
    19261 ttgttgcctg atgacagcat tttacgagcc agcatccaac accagtgcaa agcggaaatt
    19321 gccggaaaat tggctgggag caagcatgca gaatttaata atgccgaatt actcaacagc
    19381 aaatccccga cataatcccg gttctcagga ggtgttatgt cactcgccat tgtttacacc
    19441 cgcgccgctc tcgggatcgg tgccccgctt atcacggttg aagttcatat cagcaacggg
    19501 ctcccaggcc tgacaatggt aggactgcct gaaacaacgg ttagagaagc gcgtgaccgg
    19561 gtacgtagtg cgattatcaa cagcggttac gcttatccgg cgaaaaaaat caccatcaat
    19621 ctggccccgg ccgatctgcc aaaagaaggg ggaagatatg atttacctat cgctctcgcg
    19681 cttctggtgg cctcagagca gctaaaggct cccaggctaa atcaatatga gtttgtcggc
    19741 gagctggcgc ttacaggcgc tctgcgtggc gttcctggtg ccatatccag cgccatggag
    19801 gccataaaag cggggcggag gattgttgtc tctaatgaga attctccaga ggtggggtta
    19861 atcggcggca gtgactgcct tatcgccacc gatctccagg aagtctgcgc ttttctagaa
    19921 ggtcgacata ccctggctaa cccccttcca gaaggagaat attcggatga aacatcggtt
    19981 gatctgcgtg atgttattgg ccagcggcag gggaaacgag cgctggaaat catcgctgca
    20041 ggtggtcaca acctgctgat gataggcccg cccggcacag gaaaaacgat gctcgccagt
    20101 cgattaccgg gactactgcc gccgctgagt aatcaggaag cgctggaaag cgcggcaata
    20161 cttagcctgg tcgattccag gcatgccatg aaaaattggc gccgcaggcc ctttcgtgcc
    20221 ccgcatcata gcgcctccct ggcggccatg gtgggcggag gctcaattcc ggcaccggga
    20281 gagatctccc ttgcccataa cggagtcctg ttcctggatg agctgcctga attcgaacgc
    20341 agggtgctgg atgcgttacg cgaacccatt gagtcagggg ttatccatat ctcacgcacg
    20401 cgcgccaaaa tcgattatcc agcccgtttc cagcttattg cagcgatgaa tcccagcccg
    20461 acagggcact atcaaggcca gcataatcgc gcttcaccgg aacagacgct acgctacctg
    20521 ggtcgtttat ccggcccgtt tcttgaccga ttcgatctct ccctggagat cccgcttccg
    20581 ccaccggggg tgctcagcca gggaacaaac gaagaggaaa gtagcgcatg cgtacgccaa
    20641 cgtgttctgg ccgcacgcga aaggcagcta tcgcggcaga aaaaacttaa cgcgcatttg
    20701 ggaaatgatg agatgaaaat ctgctgccgg cttcataaag atgacgctgt ctggctggag
    20761 cagacgctaa tacagctcgg gctttcaatc cgcgcctggc agcgcctgat taaagtgtcc
    20821 cgaactattg ccgatattga ggcagtcgaa cgcatcgaac gccatcattt gcaggaggct
    20881 ctcggctacc gggcaataga cagaatgctg agccatctac aaaaaatgat ggcgtaaaaa
    20941 aagggcttac gccctttttc ttaatcatcg ctttctgtgt aatcttccgt accttccacc
    21001 tgcggcttgc cgccggacag ggtatggaaa cgcttcggac gcttaatgcg cgccatgtac
    21061 ttaatccaga cgcgttctgc ttccgttgcg ggctcacgtt caccacggca taccgaaaca
    21121 aactgttttt catcgtcggt gacaggctcg cgtttaccta gttcgagttc attaaaggca
    21181 taaccatgac gttccagcag ttgcgcctct ttgatggtga aatctccatg acgggaaaac
    21241 ccgcgcggat aatttttatt gtcgaaaaaa cgattagttg tcgtaaagct ttccgccatc
    21301 ctacacgctc ctgattcttt ggccgagcta attatggcgc ggagtattag ttacgcttga
    21361 cagagcgtca aacaaaacat ttaaatcatc acgacaaata attttgcgga gaagagtgtg
    21421 gatacggaat tgctcaagac tttccttgag gtgagcagaa ctcgccactt tggccgagcc
    21481 gcagaggcgc tttatctgac gcagtcagca gttagctttc gtattcgtca actggagaac
    21541 cagctggggg taaatctttt tacccgtcat cgtaataata tccgtctgac ctcagccgga
    21601 gagaaactgc tgccctacgc cgaaaccctg atgaatacct ggcaagctgc gcgcaaggag
    21661 gtcgcgaatg cttcccgcca taatgaattt tcgatcggag ccagcgcttc tctgtgggaa
    21721 tgcctgctta atggatggct gggaaagctc tatacagagc cctataacct gcagtttgag
    21781 gcgcggattg cgcagcggca atcgctggtc aaacagctgc acgaacgtca gcttgatctc
    21841 ttgatcacga cagaatcgcc gaagatggat gaactaagca gtcagttgct gggtaatttt
    21901 accctggcgc tttattgcgc ctctccggct aaatacacaa atgaattgaa ttatttacgc
    21961 ctggaatggg ggcccgattt ccaacaaaac gaagcgggat tgatcggaaa tgatgatatt
    22021 cctctgctga ccaccagttc tgccgaatta gcctaccagc agctcagcgc gcttaagggc
    22081 tgtacatggt tgcccgtgct ctgggcacag gggaaaaata atctgcatac ggtgaccgac
    22141 agtgcgacgc tttcaaggcc tctctatgcg atttggctac aaaacagcga taaacaagcg
    22201 cagattcggg agatcctgaa gcacaatata ttgggataaa cgcacccctc cagggatgga
    22261 ggacgattgg cgggaaattt aaagcaaaaa aaatcctttg cctgagcaaa ggattatata
    22321 tggcaggggc ggagagactc gaactcgcga cacccggttt tggagaccgg tgctctacca
    22381 actgagctac gcccctaaag tttcttatca ttaagcctgc ttaatcagca ggcttaattt
    22441 tttaataagt ggcggaacgg acgggactcg aacccgcgac cccctgcgtg acaggcaggt
    22501 attctaaccg actgaactac cgctccaccg aatacttc
//
