LOCUS       NC_008345.1            15440 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_008345.1 Shewanella frigidimarina NCIMB 400, complete sequence.
ACCESSION   NC_008345
VERSION     NC_008345.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:49:41
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 798589
            Orig. end    :: 814029
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..534)
                     /locus_tag="ctg1_677"
                     /transl_table=11
                     /translation="VALDRIDVWFQDEARFGQQNTTTRIWATKGTRPRAVRQQQFESAY
                     LYGAVCPATGTTEAIIAPHANSEYMWEHLTLISEATESGRHALVIMDSAGWHQQDLTED
                     FDNLSILKLPPYSPELNPIEQVWQWLRQNELANRCFSGYDDIVEQCSIAWNRFIAEPER
                     VIQLCSRRWTKLTN"
     protocluster    1..15440
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[802322:805054]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3734..6465
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15440
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15440
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="4"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(548..1027)
                     /locus_tag="ctg1_678"
                     /transl_table=11
                     /translation="MNNLNLAALVKSEKRARKRMRYLALLHFTEGHSRTAIANMLKVSR
                     TSVNTWVTHYLTHGISGLDDKHNPGRPAQLSAKQLVNLKEFVQRQSLSESGGRLMARDV
                     SLFIQSEFGVTFKQANIYRLLHQLGLSWITTRSRHPKQSQDIQDAFKKLPAVNDP"
     CDS             complement(2441..3493)
                     /locus_tag="ctg1_679"
                     /transl_table=11
                     /translation="MKPSQLKSAIIMLSFAAPIFTTQANSNTDTNEELRAELQQIQQRL
                     ATLETQDRESSLLSDTQFNFYGSLRPTFGLTHTNSDDVWDVGDANSRIGFATEYQLGDG
                     LMAFAKGEFKVDIRNDGDFGDARKAYVGIEGFLGRFAIGKQAVTQEIIYDPVDIFNRSG
                     TPIAYDSASPFRLNNLVTYRKQFGDILFSADAQFDGNKGSDGSDFFNTGLRYKTDLIYI
                     AAAFYTKELEDGTDENTVGVTLAKNFESLYLAAAYQNIDKDIADGSTLDIVASYFINET
                     YKIKLGISKYDDGGNNITSGKYNAYNTTFEWHKTSKFSTFIEYQKKDFEYQETDDQIMV
                     GMRYNFDYKF"
     CDS             3583..3720
                     /locus_tag="ctg1_680"
                     /transl_table=11
                     /translation="MTVREQVPSDNAKAPTYLLQTGTPVCKVLMLYCPHQSRQSSELFD
                     "
     CDS             complement(3734..4459)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_681"
                     /sec_met_domain="Fer2_3 (E-value: 1.4e-30, bitscore: 103.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 4.4e-09, bitscore: 34.6,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00035, bitscore: 18.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRKITFNIFRYDPQDSQDKPKMERYELTETDGMTVFIALNQLRE
                     QQDTSLQFDFVCRAGICGSCAMVINGFPTLACRTLTANYPDGEITLMPLPGFELIGDLS
                     VNTGKFMRELAERLKLWLHPKPDDQDMHRLENPMAPEEAARIYELERCVECGVCVSACA
                     TKQMRDTFVGAVGMMKIARFEMDSRDNRSADDFYHVIGNQDGVFGCMTLLGCQDNCPKD
                     LPHMQQIAYLRRKMASTIL"
     CDS             complement(4456..6465)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 405.5; E-value:
                     9.9e-124)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_682"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.6e-122,
                     bitscore: 405.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-35,
                     bitscore: 120.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKLIYTDSLIIGAGLAGLRVAIATKERGLDTLVLSLIPAKRSHSA
                     AAQGGMQASLGNTVKGMGDNEDIHFQDTVKGSDWGCDQDVARMFAHCAPKAIRELTNWG
                     VPWSRISAGPRDVIMNAKKVTLHEAEEAHGLINARDFGGTKKWRTCYTADGTGHSLLYA
                     VDNQAISMGIPVHERIEALSLIHDGKRCHGVIARCLVTGELRAYVAKSTTIATGGYGKI
                     YEISTNATICEGIGQALALETGVATLGNMEAVQFHPTAIVPAGILTTEGCRGDGGILRD
                     KDGHRFMPDYEPEKKELASRDVVSRRMTEHIRKGKGDDSPYGPHLWLDITILGREHIET
                     NLREVKEICEYFLGIDPCKEWIPVRPTQHYSMGGVRTNATGESPQLKGLFSVGEAACWD
                     MHGFNRLGGNSVAETVVGGMIIGKYVADFCEQNALEIDTALTQKFLDKLQNEIDNLVDG
                     KGTENPFEIKKEMQRIMMNYVGIFRNGPELDKAIAELKALLLRAKNLGLKCKKRHSNPE
                     LVEALRVTRMLKVALTVACGAAARTESRGAHSREDYPQRNDKDWLNRTLATWPNDESLE
                     PVLHYEKLDVMKMELPPGYRGYGNDNNIAHPDTEKRTQEINKITAELGDAPDRHALQQA
                     LMPYTLPSHLQPANERLSDTLAVIPSQPVGNKSL"
     CDS             complement(6669..7394)
                     /locus_tag="ctg1_683"
                     /transl_table=11
                     /translation="MSEKTRVPTAINGGPFGQAWSARADCLQSLTGVLLGAFLLVHMHF
                     EASILLGKETFYRFVQVLEGGMFSATGHGWPLVTQIFSVFILVIVVVHAALALRRFPVQ
                     LGQWRALRGFMSNIKHKDTRAWYWQMITGFILFFLVSAHLATMILDPKIGPHLSADRVY
                     NGHAWLLYVVFLPVVLVHGLIGLYRVILKWGVSNNRSLIRTIAQVLMIYLLCLGSLSLI
                     TYISIGSELTLPVQPFIPK"
     CDS             complement(7532..8833)
                     /locus_tag="ctg1_684"
                     /transl_table=11
                     /translation="MIILEIIIVLGAIYLGARMGSMGIGFAGGVGVLILTAGLGLTPGT
                     IPIDVILIIMSVITAIAAMQVSGGMDYLVSLAEKLLRKHPKQITFLAPVVTYFMTLFAG
                     TGHTAFSTLPVIAEVAKEQGIRPSRPLSIAVVASQVAITASPISAAVVFFSGILEPLGV
                     DYLVLLAVCIPSTFLACMVGAVVANLMGKPLAEDPIYQDRLAKGLIKKRGATQINIKDG
                     AKRSVVIFLMAIAAVMIYATAISDKVGLIVNPVLPRDSAIMVIMLTAAAAITIFCKLDA
                     SEISNAATFKSGMSACVCVLGVAWLGDTFVANHIDEIKDLAGTLLQSQPWLLSVTLFFA
                     SMLLYSQGATTKALMPAALAIGVSPLTAVASFAAVSALFVLPTYPTLLAAVEMDDTGST
                     RIGKAVFNHPFLIPGVVTIATSVALAFLFGGMII"
     CDS             complement(8946..10388)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_685"
                     /sec_met_domain="Lyase_1 (E-value: 1.2e-102, bitscore:
                     341.4, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 4.2e-18, bitscore:
                     63.5, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNTNSTRIEEDLLGTKEVSNKFYYGIHTLRAMENFKLSNQKISD
                     APELVRGMMLTKKAAAMANSELGAVSPEIANKIIEACDLILTTGQFVDQFPVDVYQGGA
                     GTSVNMNTNEVLANVALELMGLEKGRYDVINPNDHVNKCQSTNDAYPTGFRIALVNSTD
                     TLLEALTDLISAFDTKATEFKTVLKMGRTQLQDAVPMTLGQEFHAFAVTLREEIKSIKR
                     CQELLLEVNLGATAIGTGLNTPIGYSSLAIKHLAEITGREYVPAEDLIEATSDCGAYVM
                     LHSAIKRMAIKMSKICNDLRLLSSGPRTGFNDINLPQLQAGSSIMPAKVNPVIPEVVNQ
                     VAFKIVGNDITITMAAEAGQLQLNVMEPVIGQAMFESLSLMGNACIALREKCVEGITAN
                     PDVCMNHVLNSIGIVTYLNPFIGHHEGDIIGKICAQTGKNVREVVLERGLLTVEELDEI
                     LSVENLMHPKYQAKRNTSKTKV"
     CDS             10895..11845
                     /locus_tag="ctg1_686"
                     /transl_table=11
                     /translation="MNFSIRKLLLSVTLGLFLSSAVQALPQVRIIATGGTIAGVGQSAT
                     ESNYQSGEVGVNSLIAAVPEIKLLAEIQGEQLVKIGSQDMNDKVWLDLAKRINILLADK
                     NVDGIVIIHGTDTLEETAYFLNLTVKSDKPVVLVGAMRPSTAMSADGPMNLYNAVAIAA
                     NLESKGRGVLVVMNDTVLNARDVTKTNTTGVHTFAAPNFGPLGIIHNSKVEYMGRTERQ
                     HTTQTPFDISKLDILPKVGIVYNYANASDLPAKAMVEAEFDGIISAGVGNGNIYHSVFD
                     TLIKASKKGILVVRSSRVPTGATTLDCSGIVILAT"
     CDS             11890..12201
                     /locus_tag="ctg1_687"
                     /transl_table=11
                     /translation="MRSITRKTFSAEFKLEAAQLVLDKNHSIIEAAKAMNVGKSTMDKW
                     VRQLKLERQGGTPKASPITPEQIEIRELKKQVARLEEHNLILKKATALLMSDSMNNLR"
     CDS             12255..13067
                     /locus_tag="ctg1_688"
                     /transl_table=11
                     /translation="VHRSSYKYWLKRKEHIDADFTILCSEVKAAHRISNGSAGARTIAQ
                     LVTNKGINLSRYRARNLMRKLGLLSCQQPKHSYRKAAQEHVAIPNTLNRQFAVTQPDQV
                     WCGDVTYVWVGNRWAYLAVVLDLFSRKPVGWALSLSPDSELTSKALKMAFELRGKPENV
                     IYHSDQGSHYTSLKFRQLLWRLQIEQSMSRRGNCWDNAPMERFFRSLKSEWVPASGYGN
                     FTEADKAITNYITGYYSETRPHQYNGGLTPNESERLYWNDSKTVANIT"
     CDS             13064..13216
                     /locus_tag="ctg1_689"
                     /transl_table=11
                     /translation="LTTTDAEIDDAKYGFVAAGNLNPQKARILLMLSLTQSKDPQQIQR
                     WFQQF"
     CDS             13753..13920
                     /locus_tag="ctg1_690"
                     /transl_table=11
                     /translation="MLKVKGVNQASLIKKMSRLLLILQIHEINSHNNCSSYYYSDAFKL
                     ILFRFNLNEL"
     CDS             complement(14079..15440)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_beta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_691"
                     /sec_met_domain="SDH_alpha (E-value: 8.3e-96, bitscore:
                     318.5, seeds: 645, tool: rule-based-clusters)"
                     /sec_met_domain="SDH_beta (E-value: 9.5e-55, bitscore:
                     183.1, seeds: 368, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISVFDIYKVGIGPSSSHTGGPMKAGKEFIDELRSKGKLREITRI
                     TVDLYGALSLTGKGHNTDIAIIMGLAGNLPEDVDIESIPSFIARLEKSERLPVGMHCHT
                     VSFPYNKSIHFHNTNLKLHENGMQIHAWIENEKVLSKTYYSIGGGFIVDEENFGKQEEQ
                     LVKVPYEYSTAEELIKHCKTEGLSISSLVLENEKSLRPEGNIQAQFTHIWKTMRESMDR
                     GMNTQGVLPGPMRIPRRAAALCQQLVASESTSNDPMAVIDWVNMFAFAVSEENASGGRV
                     VTAPTNGACGIVPAVIAYYDKFIHRVTEKDYMRFLAASGAIGGLFKQNASISGAEVGCQ
                     GEVGVACSMAAAGLVELLGGSPEQVCIAAEIGMEHNLGLTCDPVSGRVQIPCIERNGIN
                     AVKAINSARMALRRSSDPLVSLDKVIETMMETGKDMNSKYRETSLGGLAIKVLC"
ORIGIN
        1 ttaattggtc aattttgtcc aacgtctaga acatagttga atcacccttt ccggctctgc
       61 aataaatcga ttccatgcaa tggaacactg ctcaacaata tcgtcatatc cactaaagca
      121 acgatttgcg agttcattct gacgaagcca ttgccacact tgttctatag ggttgagttc
      181 tggcgaatag ggcggaagct taaggatact aaggttatca aagtcctcag tcagatcttg
      241 ttgatgccaa cctgcactat ccatgatgac caaagcatgg cgacccgatt cggtagcctc
      301 tgaaattaat gttaaatgct cccacatata ttcactgttg gcatgcgggg caataatagc
      361 ctctgtcgtg cccgttgcag gacacaccgc accatataaa tatgctgatt cgaactgttg
      421 ttgccttacc gctcgtggtc gggttccttt cgttgcccaa atgcgggtcg tggtattttg
      481 ctgaccaaat ctagcttcat cttgaaacca aacatcaatg cgatctaacg ccacatgacc
      541 aggggtgtta aggatcgttg acagctggaa gttttttaaa agcgtcctga atatcttgag
      601 attgttttgg gtgtcgagaa cgggtcgtta tccatgacaa tcctaattga tgcagtaatc
      661 tgtagatatt tgcctgttta aaggtcaccc caaattcaga ctgaataaaa agactgacat
      721 ctcttgccat caatcttccg ccactctcag acaagctttg acgttgtaca aattctttca
      781 gatttaccag ttgtttcgcc gatagttgag cgggtctacc tggattatgt ttatcatcta
      841 ggccgctaat gccatgagtt aaataatgag taacccaagt atttacactg gttctactga
      901 ccttcagcat gttggctata gcagtacgag aatgaccttc ggtaaaatga agtaaggcga
      961 gataacgcat acgtttacgt gcgcgtttct cagatttaac taatgctgca agattgagat
     1021 tattcatcga tactgaagta aggaaatgac gagcaattag atcacatatt taatgtaaat
     1081 ggtattaatg caagaaaaca tcaaacgata gcgttaattg aatcgttatc gagagagaaa
     1141 acatcgtcaa acagctttgt catttgtttg gaatatcgtg tggtagctaa cattatcatc
     1201 tcaaacatcg tggattagta aagcctgagt gtgagaagtt acgccagcaa gcaattgcaa
     1261 tccaccgtga tagtcgtggc ttagcaggag ctagaaaagt agctggctag cttaatcagt
     1321 ttggtgaaaa tgttggccgt tatatggttg cgagattaat gagttatgca ggactcatca
     1381 gtagtcaatc cagaaagcat agttacaaga tagcgaatga tgagtctaca atcgcgtcta
     1441 acttgttaaa gcggctgttt aacgttgacg ctataaaccg gtttggtttg gcgtgtggat
     1501 gtgacgtgcg tttgatctgg agccaaatgg ctctacttag cggtatgatc tacacataaa
     1561 ttggctagat tggctaactt gcctgaaaaa actgcaattg agcactttat tataaaaagt
     1621 actttacctt tggtggtggt tttagcataa tgcccctcgt caacaggggt gtagttccaa
     1681 ttggtagaac agcggtctcc aaaaccgatg gttgcgagtt cgagtcttgc cacccctgcc
     1741 aaataaaaca acggcttgca tagaaatatg cgagccgttt ttaattgtgt aaaatatagc
     1801 ttagaaaaag aaagtttaac atctgcattg ctgttattac ccctttgtgc ctttgtaatt
     1861 tatattctta gacatatgag tataaatttt tgtttctctc tttatatagg ctttcttgtt
     1921 cctgtttcac tttcattgta gctaagatca acctggcgtt tctgagttaa cctgctgttt
     1981 tttcattggt gatggaaatg cttgtcgctc ttatgtgcat ttttatttag ttgactactc
     2041 atttcatcct cattatgcct ttatttgttt cttatccatt tcccttggaa aacgattagt
     2101 cagtagaact ctgcaaagcc taggtttgta ttttcttagt tttttttcga caatttcttg
     2161 aactactgtc agtagtattt tcgatttatg cactgaatat tctgatgttt tatggataat
     2221 tgactacgga gaattaacat tatgcgttaa tcctccgtaa cgtgttctta acggaatatc
     2281 aggggggtta gatttatact gttagtgtat ttaaaagtag tagttaacca tgttaaccat
     2341 ggctagtttg ctcatgctta cagtatctaa tggcactcta ataaatataa gcttcttagg
     2401 gcgccattac ttttactgaa tcatgaagtt gatttacggc ttaaaactta taatcgaagt
     2461 tataacgcat accgaccata atttgatcat cagtctcttg gtattcaaaa tcttttttct
     2521 gatattcgat gaaggtactg aatttcgatg ttttatgcca ttcaaaggtt gtgttatagg
     2581 cattatactt acctgaggtg atattgttgc caccatcatc atatttggat atccccagtt
     2641 taattttata ggtttcattg atgaagtagc ttgcgactat atcaagagtt gaaccatcgg
     2701 cgatgtcttt gtctatgttt tgataagcag ctgctaggta cagtgactca aagtttttag
     2761 ctaaggtgac acctacggta ttttcatctg taccgtcttc caattcttta gtgtaaaacg
     2821 ctgcggctat gtagattagg tcggttttgt aacgtaaacc ggtgttaaaa aaatcactcc
     2881 catcacttcc tttgttacca tcgaattgcg catcagcaga aaacaaaata tcgccgaatt
     2941 gctttctata ggtcactaga ttgttaagtc taaatggact tgcactgtca taggctattg
     3001 gggttcctga acgattgaag atatcgacgg gatcgtaaat aatttcttgt gttactgctt
     3061 gcttaccaat agcaaaccga cctaaaaaac cttcgattcc aacataggct tttcgtgcat
     3121 cgccaaagtc accatcattt cttatatcaa ctttaaactc gcctttagca aaggccatta
     3181 ggccatctcc taattggtat tccgtcgcaa aaccaatccg tgagttagca tctccaacat
     3241 cccacacatc atctgaattg gtatgggtaa gaccgaatgt cggacgtaaa gaaccataaa
     3301 aattaaactg ggtatctgag agcaaagatg actctctgtc ttgggtttca agcgtggcga
     3361 gcctttgctg aatttgttgt agttcagctc gtaactcctc attagtatcg gtgttgctat
     3421 tagcttgagt tgtgaatatg ggagccgcaa agctcagcat aataattgca gattttagtt
     3481 gggacggttt catttatgtt tccttacata acaactacta gtgttctgct actggtttgg
     3541 ttaccgatta aacagtactg ctagtagtaa ggatgtgcac ttatgacagt gcgtgagcag
     3601 gtgcctagcg acaatgcaaa agctcccaca tatttactgc aaacaggaac gcctgtttgc
     3661 aaagttttaa tgctgtattg ccctcatcaa tctcgccaaa gcagcgagct ttttgattaa
     3721 aggacttttt tgactagaga attgtcgagg ccatttttcg gcgtaaataa gcaatttgct
     3781 gcatgtgggg caagtcttta gggcagttat cttggcaacc taacagcgtc atgcagccaa
     3841 agactccatc ttgattgccg ataacatggt agaagtcgtc tgcgctgcgg ttgtctctac
     3901 tatccatttc gaaacgggca attttcatca tgcctacagc gcccacaaag gtgtctcgca
     3961 tttgtttggt ggcacatgca gagacgcaga caccacattc gacacagcgt tccaattcat
     4021 atatccgcgc ggcttcttct ggtgccattg gattttctag gcgatgcatg tcttgatcgt
     4081 ccggtttagg atgtaaccag agctttaatc gctcggctaa ttcacgcata aatttcccgg
     4141 tgtttaccga caagtcacca atcagttcaa agccaggtag aggcattaag gtgatttcac
     4201 catcagggta atttgccgtt aaggtacgac aggcaagcgt tgggaagcca ttaatcacca
     4261 tggcgcaact gccacaaata cctgctcggc acacaaagtc gaactgtaac gaagtatctt
     4321 gttgttcacg gagttgattt aatgcgataa acactgtcat accatctgtt tcggttaatt
     4381 cgtaacgttc catttttggc ttatcttggc tatcttgtgg atcgtagcgg aagatattaa
     4441 aggtgatttt tcggctcata atgatttatt tcctaccggt tgagatggta tgactgctaa
     4501 tgtatcgcta agacgttcat tagctggttg tagatggcta ggtagcgtat atggcatcaa
     4561 tgcttgctga agtgcatgcc tatctggggc gtcgccaagt tctgccgtta ttttgtttat
     4621 ttcttgagtt cgtttttctg tatcgggatg ggctatgttg ttatcgttgc cgtaaccgcg
     4681 gtatccagga ggtaactcca ttttcattac atcgagcttc tcataatgta aaacgggttc
     4741 taatgactcg tcatttggcc aggtagccaa tgtacggttt agccaatctt tatcattgcg
     4801 ttgtggataa tcttctctcg agtgggctcc acggctttcg gtgcgtgcag cagccccaca
     4861 agcaacagtt aaggctactt tcaacattct ggtgacgcgc agagcttcga ctaattcagg
     4921 atttgaatga cgttttttac acttaagtcc tagatttttt gcgcgtagaa gtaatgcttt
     4981 aagctcggct atagccttgt ctagttcagg gccatttcga aagatgccga cgtaattcat
     5041 catgatacgt tgcatttctt tttttatttc gaaggggttc tctgtacctt taccatcgac
     5101 taagttatcg atttcatttt gtaacttatc gagaaatttt tgggtaaggg cagtatctat
     5161 ttctaaggca ttttgttcac aaaaatcggc tacatactta ccgatgatca tgccgcctac
     5221 tacggtttct gccacagaat taccacctaa acgattaaaa ccatgcatat cccagcatgc
     5281 agcttctcca acactaaata gtcctttaag ttgtgggctt tcaccggtgg cattagtacg
     5341 aacgccgccc atagaataat gctgggtagg tcttacaggg atccactctt tgcagggatc
     5401 gattccaaga aaatattcac aaatttcttt cacttcgcgc agattggttt caatatgctc
     5461 acgacctaaa atggttatat ctaaccagag atgtggcccg taaggactgt catctccttt
     5521 acctttgcga atatgttcgg tcatgcggcg agataccaca tcacgggaag cgagttcctt
     5581 tttctctggc tcgtagtctg gcataaagcg atgaccgtct ttatcgcgta gtatgccgcc
     5641 gtcaccgcga caaccttcag tggtgagaat tcctgctggg acgatggctg tcggatgaaa
     5701 ctgtaccgct tccatattgc ctaatgtcgc gacgccagtt tcgagtgcta acgcttggcc
     5761 tataccttcg cagatagtgg cattagtcga tatttcataa attttgccgt aacctccagt
     5821 cgcaatcgta gttgatttag ccacataggc gcgcagctct ccggtcacta aacaacgtgc
     5881 aattactccg tggcaacgct taccatcatg gatcagtgat aaggcttcaa tcctttcgtg
     5941 taccggaata cccatcgata ttgcttggtt atctaccgca tacaataatg agtggccagt
     6001 accatcggcg gtatagcatg ttcgccattt tttggtgccg ccaaaatctc gagcattgat
     6061 gaggccatga gcttcttctg cttcatgtaa cgtcaccttt tttgcattca ttattacatc
     6121 gcgtggacca gcagaaattc tagaccaagg cacaccccag tttgtcagtt cacgtatggc
     6181 tttgggggcg caatgggcaa acatacgtgc cacatcttgg tcacaacccc agtcagaccc
     6241 ttttaccgta tcctgaaaat gtatgtcttc gttgtcaccc atacctttaa ctgtgttgcc
     6301 aaggcttgct tgcataccgc cttgagcagc cgcggaatgt gaacgttttg ccggaataag
     6361 cgataatacc agtgtgtcta ggccgcgttc tttggtggca atggctactc taaggcctgc
     6421 tagcccggca ccaatgatta atgagtctgt ataaataagt ttcaaaatca gctccttatc
     6481 taatgatcta gataatatgt atgaatttca attacgcctc tgcgatagat gtaatgcacc
     6541 tattcgtcag agaaggatct gtgtgttgag gcttagcctt gctattcagg gtggaagctc
     6601 atttagttat tgactctggc tgtttgttgc caggcaatca cacttagcgt ccccccttag
     6661 catgcctatt acttcggaat aaacggctga acgggtagtg tcagttcact gccaatagag
     6721 atgtaggtaa tgaggcttaa tgaacctaaa caaagtaaat agatcattaa cacctgggca
     6781 attgtgcgta taagagaacg attattgctc actccccatt ttaatatcac tcggtataag
     6841 ccaattaagc catgtactaa tacaaccgga aggaatacca catacaagag ccaggcatgt
     6901 ccgttataga cgcggtcggc tgagaggtgt ggaccaattt taggatctaa aatcatggtt
     6961 gcaagatgtg ctgagactaa gaaaaataag atgaatccag tgatcatttg ccaataccaa
     7021 gcgcgagtgt ctttgtgctt tatgttggac ataaacccac gaagtgcacg ccactggcca
     7081 agttgtaccg gaaagcgacg taatgctagc gccgcgtgaa cgacgacgat aactaaaata
     7141 aatactgaaa agatttgtgt cactagtggc caaccgtgcc cagtagcgct aaacatgcca
     7201 ccttcaagta cttgcacgaa gcggtagaag gtttctttgc ctaataaaat gcttgcctca
     7261 aaatgcatat gcactaataa gaaagcgccc agtaaaacac ccgtcaaact ttgtaaacag
     7321 tcggctctag ctgaccaggc ttgtccaaat ggtccaccgt tgatggcggt tggaacgcgc
     7381 gttttttctg acattaattc acctcttata actttgttat gatgtaaatg cgtaagcatt
     7441 accccaaaac aaagtctcta tataaagatt aaaggaacgg ggttaatcca ttttctggat
     7501 tagcccttcg attactttgt ttaacattga gctatataat catgccgcca aataagaacg
     7561 ctaacgcgac actggtagca attgtcacta caccagggat gaggaatggg tggttaaata
     7621 ccgccttacc aattcgagtt gagcctgtgt catccatttc gacagctgcc agtagcgttg
     7681 gataagtagg tagtacaaac aacgcactca cagcagcaaa agaggcaacg gcagttaaag
     7741 ggctcacacc aatggctaat gccgcaggca tcagcgcttt agttgtggcc ccttgtgagt
     7801 agagcaacat agaagcgaag aatagtgtta ccgacaataa ccatggctgg ctctgcagta
     7861 aggttcctgc aaggtctttg atttcatcaa tatggtttgc aacaaaagta tcccctaacc
     7921 acgcaacgcc tagcacacag acacaggcag acatacctga cttaaaagtg gcagcattag
     7981 aaatttcgct agcgtctaat ttacaaaaaa tcgttatagc cgcagcagca gttagcataa
     8041 tcaccatgat ggctgaatcg cgaggcaata ccggattaac aattaatccc actttgtcgg
     8101 aaatcgcagt ggcataaatc atcacagccg caatagccat taaaaaaatc accactgaac
     8161 gtttagcacc gtctttaatg tttatttggg tagcaccacg ttttttgatt aatcctttag
     8221 ccaaacggtc ttggtaaatc ggatcttctg ctagcggttt acccattaaa ttggctacta
     8281 cggccccgac catacaagcg agaaaagtgg aggggataca tactgctaat agcactaaat
     8341 agtccactcc aagtggctct aagatgccag agaagaacac tactgccgct gaaataggtg
     8401 aggcagtaat ggcgacttga gatgctacaa ctgcgataga tagaggtcga gatggacgta
     8461 taccttgttc tttggctact tctgcaataa caggtaaagt tgagaatgct gtgtgacccg
     8521 ttccagcaaa gagtgtcatg aaataagtga cgacgggtgc tagaaaggta atttgttttg
     8581 gatgtttacg tagtaatttc tcagccagtg agacgaggta gtccatccct cccgatactt
     8641 gcatggctgc aatggcggtg atcaccgaca taatgattag gattacatca atcgggatag
     8701 tccctggtgt tagcccaagt ccagctgtca gtatcagcac tccgacaccg ccagcaaagc
     8761 cgatccccat gctccccatt cttgcaccta ggtaaatcgc cccaagtacg ataattatct
     8821 ctaatataat catggtatta actctttgtt attttgattg tcatattctg cttaaggtta
     8881 attatgcaga agcttattgt ttaataatcg agtttgggtt ggagagaatc tccaacccaa
     8941 cagagttaca ctttggtttt gctagtattt cgtttagcct gatacttagg atgcattagg
     9001 ttttcgacag agaggatttc atcgagttct tcaactgtta ataagcctcg ttctagcacc
     9061 acttcacgga catttttacc cgtttgggca caaatttttc cgataatgtc gccttcatgg
     9121 tgaccgatga acggattaag ataggtcacg atgccaatgg aatttaatac atgattcata
     9181 cagacatcag gattggctgt gatcccttca acacacttct cacgcagtgc gatacaggca
     9241 ttccccataa gacttagcga ctcaaacatc gcctggccaa tgacaggttc cattacgtta
     9301 agttgtaact ggccggcttc tgcggccata gtgatcgtaa tatcgttacc gacaatttta
     9361 aaagccactt ggttaaccac ctctgggatc acagggttga ccttggcagg catgattgac
     9421 gaaccggctt gtaactgagg caaattgata tcattgaatc ctgtgcgtgg acccgatgaa
     9481 agcaagcgta aatcgttaca gattttggac attttaatgg ccatacgctt aattgcactg
     9541 tgcagcataa cgtaggcgcc acaatccgat gtcgcttcaa ttaaatcttc tgctggcaca
     9601 tattcacgtc cagtaatttc agccaaatgt ttaatggcca atgaggagta ccctattgga
     9661 gtgtttagac cagtaccaat agccgttgcg cctaaattca cctcaagtaa taattcttgg
     9721 caacgtttaa ttgatttaat ttcttcgcgc agtgttacag caaaagcgtg aaactcctgg
     9781 cctaatgtca taggcacagc gtcttgtaac tgagtgcggc ccatttttaa tacggtcttg
     9841 aattctgtag ctttagtgtc gaaggcactg atgaggtcgg ttaatgcctc caataaagta
     9901 tctgtgctgt tgaccaatgc aattctgaaa cctgttggat aagcatcatt agtggattga
     9961 cacttattaa catggtcatt agggttgatg acatcatagc ggcctttttc tagccccatg
    10021 agttccaatg caacattggc taatacttca ttggtgttca tgttgaccga ggtaccagca
    10081 ccaccctgat aaacatctac tgggaattgg tcgacaaatt gacctgtcgt gaggatcaga
    10141 tcgcaggctt caataatttt attcgcaatc tcgggactta cagcccctaa ttcgctatta
    10201 gccatggctg ccgctttttt tgttagcatc atgcctcgta ctaattcagg tgcgtcggaa
    10261 attttttgat tacttaattt aaagttttcc attgcacgta atgtgtgaat gccataataa
    10321 aatttattag aaacttcttt agtacccaat aaatcttctt cgatacgtgt gctattagtg
    10381 tttttcattt ctatcctatt aaatcctgtt aatagtaaga tatattttcg accttgagct
    10441 atggtatgtg tatataagct taaattgcat atcaaaaata actcttcgaa aatatgaagg
    10501 ggaactttcc ccttaactat tgggtgagag attacccctt aaggagtatt taaatataga
    10561 tggagatcac ttatttgtat ctggttatag attttgttta gttgttggat aaatatctca
    10621 actgaattga tttgtgtgat ctattactgt ttgttctaag ttgtatgttg aattgttatt
    10681 tttttgtcaa cttaagattt aaaggtggaa atgttttttg gtaaaagtat tgtgttaatt
    10741 aaaagtgtct ttatttaaat tgttttatta ttcatttttt tgatttagat tattatttgg
    10801 tcttagttgt taattttagt gataactatc acggtgagaa tttaataata gtgcacactt
    10861 gtgaagtgtt tattattaat aaaaggaagt tagtatgaat ttttctatac gtaagctctt
    10921 gctatcggtt accttagggt tatttctatc ctctgcggtg caagcgcttc cacaggttcg
    10981 aattattgcc accggtggga ccattgctgg agtgggccaa tcggctactg agtcaaatta
    11041 tcagtctgga gaggtcgggg ttaatagctt aatagcagct gtgccggaga taaagttgct
    11101 tgccgaaatt caaggtgaac aactcgttaa aattggttcg caagatatga acgataaagt
    11161 ttggttagac ttagccaaac ggattaatat tttactggct gataaaaatg tcgatggaat
    11221 tgtgattatc catggcactg atactttaga agaaactgct tactttttga atctaacagt
    11281 caagagcgat aagcctgtag tgctggttgg tgcaatgcgt ccatccactg ctatgagtgc
    11341 cgatggacct atgaatctgt ataatgcagt cgccattgcc gctaatctag agtctaaagg
    11401 cagaggtgtt ttagtcgtga tgaacgatac agtacttaac gcccgcgatg taacgaagac
    11461 taatactact ggagtacaca cctttgccgc gcctaatttt ggcccgcttg gtattattca
    11521 taacagtaag gttgagtata tgggcagaac ggaacgtcaa catacgactc aaaccccttt
    11581 tgatatcagc aagctcgata ttttaccaaa ggtaggtatt gtttataact acgctaatgc
    11641 tagtgattta cctgctaaag ctatggttga agcggagttt gacggcatta ttagtgcggg
    11701 tgtaggtaac ggcaacattt atcactctgt attcgataca ctcattaagg cgagcaaaaa
    11761 aggcatattg gttgtccgct ctagccgtgt accgaccggt gccactactc tagattgtag
    11821 tggcatagtt attttggcca cctaaataga ggtgatatta ttacctcgta catgacttta
    11881 ggtgaacaca tgagatcgat aaccagaaaa acatttagtg ctgaattcaa acttgaagca
    11941 gcccaattag tcctcgataa aaaccatagc atcatcgaag cagcaaaggc gatgaacgtg
    12001 ggtaaatcaa ccatggataa atgggtgaga cagttaaaac tagaacgcca gggtggcacg
    12061 ccaaaagcct ctcccattac ccctgaacaa attgaaatcc gtgaactgaa gaaacaggta
    12121 gcccgtcttg aggagcataa tcttattcta aaaaaggcta ccgctctctt gatgtcagac
    12181 tcgatgaaca atttacgctg atcagcgcac tcaagcagag ccactctatt ctcacaattt
    12241 gtaatgcatt caaagtgcat cgaagtagct ataaatattg gctaaaaaga aaagaacata
    12301 tcgatgctga ctttactatt ttatgcagtg aagtgaaggc cgcgcatcgt attagtaatg
    12361 gctctgccgg tgctagaacg atagcgcaat tagtgactaa caaagggatt aatctcagtc
    12421 gttatcgagc ccgtaatcta atgagaaagc ttggattatt aagctgtcag cagcctaagc
    12481 attcttatag gaaagctgca caagagcatg tagcgatccc aaacacgctt aatcgacagt
    12541 ttgcagtaac tcaaccagat caagtgtggt gtggcgatgt gacgtatgtt tgggtcggta
    12601 atcgttgggc atatttagcc gttgttttag acttattttc ccgcaaacct gttgggtggg
    12661 ctttgtcatt atcgcctgac agcgagctga cctctaaagc cttgaaaatg gcatttgagt
    12721 taagggggaa acctgagaat gtgatatatc acagcgacca aggttcacat tacacaagct
    12781 tgaaattcag acagttatta tggcgtcttc agattgagca aagcatgagt cgtcgcggga
    12841 attgttggga taacgcacca atggagcgtt tctttagaag tttgaaatct gaatgggtac
    12901 ccgcaagtgg ctatgggaat tttacagaag cagacaaagc gatcacaaat tacatcactg
    12961 gatattacag tgaaactaga ccccatcaat ataatggtgg gttaactcca aatgagtcag
    13021 aacgtttata ttggaatgac tctaaaaccg tggccaatat tacttgacca ctacagatgc
    13081 tgaaatagat gatgccaaat acggctttgt tgctgctggt aatcttaatc cacaaaaagc
    13141 ccgtattttg ttgatgttat cgttaactca aagtaaagac cctcaacaaa tccagcgctg
    13201 gttccagcag ttttaggcac tagctgaggc acaaaacact agattaaatc tacattttta
    13261 tgaagccagt agtcaccact actggctttt tttatgtact ttattctagt tatagcgtct
    13321 atcttcctaa taaaaattac ataacactcc ctacaatata ctatgcctgt agtgcagtag
    13381 tcttaatagt cagtaaccta gttagtacac cttggttaac gctatttata aagtatttta
    13441 ttagggatcc ccccaaaaaa actttacgga acaagcctaa gtaacaatta ataaacatta
    13501 atcttaacag agtaatctat taaagtgctc gaggaaatac aggtggtcaa cgattatctg
    13561 agtatgctta tactcattgt ctaaatgggt aaaaaagatg agagtgttat tggcagtgtt
    13621 aatcgtaata tttattaata gataaaataa agattgtatt taactaagcg ttaactacaa
    13681 cttatgtatg aattgaatag atggttaaag ttgtttgtga ctttaaattt ccattgcgag
    13741 gattaagttt taatgctaaa ggttaagggt gtcaatcagg catcgttaat taaaaagatg
    13801 agccggttac ttctcatctt acaaatacat gaaataaaca gccacaacaa ttgcagtagc
    13861 tattattatt cagatgcttt taaattaata ttattccgtt tcaatctgaa cgagttgtga
    13921 aagcgaaagt tttttatatg agcttattcg tatttttaaa ctcttaaata atattaaatt
    13981 aaatatagag ttggttttgt tttaggtttt tattttttaa ttaaaataaa atcatataaa
    14041 gttaccagca ataaagattg catctaatat ttttaacatc agcaaagaac tttgatagct
    14101 aatccaccca aagaggtttc tctatattta gagttcatat ccttacctgt ttccatcatt
    14161 gtttcgatga ctttatcaag agacacgaga ggatctgaag aacgacgtag tgccatacgt
    14221 gcagagttaa tcgcttttac tgcgttaatt ccattacgtt caatgcaagg tatttgcacc
    14281 cttccagata ctgggtcgca agtcagtccc aggttgtgtt ccataccaat ttctgcagcg
    14341 atacatactt gttcaggact accacccaat aactcaacaa gccctgccgc agccattgaa
    14401 caggcgactc caacctctcc ttggcagcca acttccgctc cagaaatgga agcattctgt
    14461 ttaaataacc cgccaatagc cccagatgcc gccagaaaac gcatatagtc tttctcggta
    14521 actctatgga taaacttgtc gtaataagca attactgctg ggacaatacc gcaagcccca
    14581 ttagtaggtg ctgtgacaac tcggcctcca gatgcatttt cttcactcac tgcaaaagca
    14641 aacatattga cccaatcaat aacagccata gggtcattag atgtagattc agaagccaca
    14701 agttgttggc aaagcgcagc agcacgacga gggatccgca ttggtcctgg tagtacccct
    14761 tgggtattca taccgcgatc catagattca cgcatcgttt tccagatatg agtaaactga
    14821 gcttgaatat taccttctgg gcgcagcgat ttttcattct ctaacactaa agagctaatc
    14881 gataatcctt cagttttaca atgtttaatc aattcttctg ctgtagaata ttcataagga
    14941 acttttacta actgttcctc ttgtttgccg aaattttctt catcaacaat gaatccgcct
    15001 ccgatagaat agtaagtctt ggagagcact ttctcgtttt ctatccatgc atggatttgc
    15061 atgccatttt catgcagttt caaatttgta ttatggaagt ggatgctttt attataaggg
    15121 aaggacacag tatgacagtg catgcctaca ggaagccttt cacttttctc cagccgtgca
    15181 ataaaactgg ggatactttc gatatcgaca tcttccggta gattacccgc tagacccata
    15241 ataatggcta tatctgtgtt gtgacccttt cctgtgagtg acagtgcgcc atataaatca
    15301 acagtaattc tagtgatttc tcgaagcttg cctttcgaac gtaactcatc gataaactct
    15361 tttcctgctt tcattggtcc gccggtatga gagcttgaag gtccaatacc cactttataa
    15421 atatcgaaaa cactaatcat
//
