LOCUS       NZ_CP083638.1          24598 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP083638.1 Escherichia fergusonii strain FDAARGOS_1499
            chromosome, complete genome.
ACCESSION   NZ_CP083638
VERSION     NZ_CP083638.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:49:32
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3443957
            Orig. end    :: 3468555
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24598
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[3453957:3458555]"
                     /cutoff="10000"
                     /detection_rule="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /neighbourhood="10000"
                     /product="Formate_dehydrogenase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14598
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /neighbourhood="10000"
                     /product="Formate_dehydrogenase"
                     /protocluster_number="1"
     cand_cluster    1..24598
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /kind="single"
                     /product="Formate_dehydrogenase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24598
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Formate_dehydrogenase"
                     /region_number="17"
                     /rules="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /tool="gutsmash"
     CDS             complement(3293..3625)
                     /locus_tag="ctg1_3213"
                     /transl_table=11
                     /translation="MISAKQINKMISQENFDAEAAMKKVAELETLVAQAKEVSKDSMNS
                     LFTGAADRYQLAAKKYVRRIRDKVPYSDWDKETLQDANTSWMVQDSYPQSLRAYNEMVG
                     NYNRLR"
     CDS             complement(3824..4321)
                     /locus_tag="ctg1_3214"
                     /transl_table=11
                     /translation="MKRNLLASAIVIGIMALGMTGCDDKKAETQTPPPANSQSAAPTAV
                     KAEAKPETAAQPVVDAEAVYNETMNVYIKCYNKLQIPVQHSLARYVDWVKDFKQGPTGK
                     ESHVYGIYSISQSNLTECEKGIKSVVALTPALEPIDGVALNYINTAVALGNTINEMDKY
                     YT"
     CDS             complement(4517..6823)
                     /locus_tag="ctg1_3215"
                     /transl_table=11
                     /translation="MDTWEWYNKYSQELRDAGQEYIPQLIDDFSESVLHLQIEKCDSLL
                     PEMKALNQVAKNPWLEIFIGHWEMRHRLTNYEEGEKVLPDVVALFEKAHREEAKDCPQS
                     ICVTQDLSACYENIDAPGWANERMAVCEETIARIDPTWSCFMCLSCEYASAMVDSNKTE
                     EALVYIDRQIEAVKASGSEYLEALLAIRADILVALQRYDEAREVIDELAKENDYWGRDR
                     ISYHLKKLYIMALCGQDEEVWEELPRWTDLTPYSWGMWVKIITVLLPRHPQRNHWQLAR
                     IIQKMLEQRSQAGAHRKVVNLAKLQITLALERESVWVAKMAMKLAQQHMPKLRALLGVD
                     REFLELSEKIAAKEAELLARPVVEVPENSDEETQPDPEKDVEIFRRAYLNTPDDAELLG
                     KLVNALNACNALNESIELLQRHVESHLQEDNGLCFDLLDLLLNRGDQQAIEHLAKLYEQ
                     AGLLHMALWFRARVINQQEDWVALEAIGQQLLQNEKGREWVGVYRMCSWAAQKQEAWDR
                     KLDYLQQLQQLMISREEDIRNLQWDIMATASILQQWDLVRAIAAELEIELTEGEGFIDE
                     KWGLLNIRFRENYEYRYYYAQRIGPVTARIIEPTYRTDYPQHVDEVVVFDAEMLNTRPE
                     DEEEQKNFTPLYGCLKTIIPTEYGESWFCEGIMPGEEEFNTFREALRERNWYYWSNSND
                     DYTLTDSHQGEGAEPLPAFYFVISAPRSVSKGDIDKILHELTADWEHPLCWWRLAKEAG
                     ANEEKHAAIAERYGM"
     CDS             complement(6825..8660)
                     /locus_tag="ctg1_3216"
                     /transl_table=11
                     /translation="MSTLQLPGSSYSTEVNLNGLIEVLSKHLYSTPVVAVRELVQNGHD
                     AIVRRRIEQPDAPKDNQIRVVADVAKSTIIISDTGAGLTESEIHGFLATVGVGYTRMLR
                     QQDDNTGLIGMFGLGFLSAFVLAKEVTVLTTSWQTPDQSWKYHSTDGQKYTVTPHQSSA
                     PGTQVILTLKEEYSHLASNNLLNRVLSRYCILLHEPVYVGDASEPVNKLQPPWREVAPE
                     GVTMHRALVQRKNLAFAAQFESSFEPICTIPVVPVGMSDAVGILWIQDGATYGTSDNRN
                     LSLFLRGMLLDDEARELLPPWAGFIGGVIESSKLTPTASREDLQRDETWVAVQEALKET
                     LISGLSDLAQNQPEIWRRVLMRHNEALLGAALCDDRLFDLLKDRLQVPTSKGALLAKDL
                     RVNNSIHILLSRDGGFEEMLFHILQRPVARGDRYAVVPFLRRWALLYHCRIIEVGTQTG
                     NEQLFSLAELPEEQVAYLEEHLCDGEQLIISRFEPAVLPLVVTPDREAELKQILEQDNA
                     DKRISTAALMLARQFTSQIQKTKTSSLYINLNNPCIMQLVTALQHQQQPAAALRLLKSL
                     KVILCSSGNKEQQWDLHQALEDFTQVIPVLINQGK"
     CDS             complement(8971..9807)
                     /locus_tag="ctg1_3217"
                     /transl_table=11
                     /translation="VKKTQQKEIKNVTNITGVRQIELWRRDDLQHPRIDEVAEEVPVAL
                     VYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRR
                     FMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQAFDLNKLDDALRHLNDFQPV
                     GQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASY
                     EMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLIHN"
     CDS             10001..10588
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molybdopterin"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molybdop_Fe4S4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3218"
                     /sec_met_domain="Molybdop_Fe4S4 (E-value: 1e-19, bitscore:
                     68.3, seeds: 55, tool: rule-based-clusters)"
                     /sec_met_domain="Molybdopterin (E-value: 6.7e-07, bitscore:
                     26.6, seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPSVALAETRQYKLLRTRE
                     TRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVNRGALCPKGAGLVDFIHS
                     ESRLKFPEYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYIAQNAEGVTVNRWLSTGM
                     LCASASSNETGYLTQKFSRALGMLAVDNQARV"
     CDS             10637..13051
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molybdopterin"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molydop_binding"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3219"
                     /sec_met_domain="Molybdopterin (E-value: 3e-21, bitscore:
                     73.8, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 1.5e-16,
                     bitscore: 58.4, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNHWVDIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIV
                     IDPRFTRTAAVADYYAPIRSGTDIAFLSGVLLYLLNNEKFNREYTEAYTNASLIVREDY
                     GFEDGLFTGYDAEKRKYDKSSWTYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDV
                     VENICGTPKDAFLKVCEYIAETSAHDKTASFLYALGWTQHSVGAQNIRTMAMIQLLLGN
                     MGMAGGGVNALRGHSNIQGLTDLGLLSQSLPGYMTLPSEKQTDLQTYLAANTPKPLLEG
                     QVNYWGNYPKFFVSMMKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKEGKVNGY
                     ICQGFNPVASFPNKNKVIGCLSKLKFLVTIDPLNTETSNFWQNHGELNEVDSSKIQTEV
                     FRLPSTCFAEENGSIVNSGRWLQWHWKGADAPGIALTDGEILSGIFLRLRKMYAEQGGA
                     NPDQVLNMTWNYAIPHEPKSEEVAMESNGKALADITDPATGAVIVKKGQQLSSFAQLRD
                     DGTTSCGCWIFAGSWTPEGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQ
                     GNPWDPKRQLLKWDGTKWTGWDIPDYSAAPPGSGVGPFIMQQEGMGRLFALDKMAEGPF
                     PEHYEPFETPLGTNPLHPNVISNPAARIFKDDAEALGKADKFPYVGTTYRLTEHFHYWT
                     KHALLNAILQPEQFVEIGESLANKLGIAQGDTVKVSSNRGYIKAKAVVTKRIRTLKANG
                     KDIDTIGIPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     CDS             13064..13966
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Form-deh_trans"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Fer4_11"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 25.5; E-value:
                     5.2e-08)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3220"
                     /sec_met_domain="Fer4 (E-value: 8.3e-06, bitscore: 23.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_11 (E-value: 2.4e-25, bitscore: 86.5,
                     seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0037, bitscore: 15.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Form-deh_trans (E-value: 1.3e-20,
                     bitscore: 70.9, seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKAC
                     QVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMHCS
                     DPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCVAGCPFDIPRLNPEDNRVYKCTLC
                     VDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAGVGGT
                     HVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHYVGVGP
                     NRADEEENNLHEEKDEERK"
     CDS             13963..14598
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Ni_hydr_CYTB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3221"
                     /sec_met_domain="Ni_hydr_CYTB (E-value: 8.6e-23, bitscore:
                     78.8, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRRDTIVRYTAPERINHWITAFCFILAAVSGLGFLFPSFNWLMQ
                     IMGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVGDT
                     GRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVALIVV
                     IMVHIYAALWVKGTITAMVEGWVTSAWAKKHHPRWYREVRKTTEKKAE"
     CDS             14595..15524
                     /locus_tag="ctg1_3222"
                     /transl_table=11
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELA
                     ENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKHWQ
                     KLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFIWAA
                     LSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEW
                     HVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAVADDLA
                     SLVLDARMEQEGYARSSINPFLFPGEGE"
     CDS             complement(15869..16090)
                     /locus_tag="ctg1_3223"
                     /transl_table=11
                     /translation="MAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQQ
                     FPVRKAKGGRQKGEEDGVEYQRKLREEW"
     CDS             complement(16505..16783)
                     /locus_tag="ctg1_3224"
                     /transl_table=11
                     /translation="MSTFNTRKDRDRNGKAKPHKHSGSPTLTGKWRHPSMDCWVNYSTP
                     GDHEWKRLYTTLRRRADDRRQCYRVMQGDDPQGIVWFPDCYPQIYYY"
     CDS             complement(16845..17057)
                     /locus_tag="ctg1_3225"
                     /transl_table=11
                     /translation="MTRNRAERRHHMARLKKIRRRYRTAGDGSKKASGVCFRTPCMCSC
                     WMCGHRRYHNGSRVSEIRAKARYAN"
     CDS             complement(17226..18167)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3226"
                     /sec_met_domain="Acetyltransf_1 (E-value: 4e-14, bitscore:
                     50.8, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAHH
                     QMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDVQDKGLGTLMAMTLESVARQEGVKR
                     VTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQLQQ
                     AWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWGLIWL
                     MLRERHLGGTIILADAHIRYSKPISGKPHAVADLGALSGDLDRLARGRKARVQMQVEIF
                     GDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE"
     CDS             complement(18212..18649)
                     /locus_tag="ctg1_3227"
                     /transl_table=11
                     /translation="MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRL
                     CERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRAEA
                     LYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV"
     CDS             complement(18646..19518)
                     /locus_tag="ctg1_3228"
                     /transl_table=11
                     /translation="MLKTIHEKARHHTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLL
                     SLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQQYIEQFVANSNKMTAV
                     GACGLIVTALLLMYSIDSALNAIWRSKRVRPKIYSFAVYWMILTLGPLLAGASLAISSY
                     LLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFE
                     AGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQA
                     AEQEEDDEP"
     CDS             complement(19512..20111)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3229"
                     /sec_met_domain="HAD_2 (E-value: 1.9e-13, bitscore: 48.8,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLYIFDLGNVIVDIDFNRVLGTWSDLTRVPLASLKKSFHMGEAFH
                     QHERGEISDEAFAEALCHEMALPLSYEQFSHGWQAVFVALRPEVIAVMHKLREQGHRVV
                     VLSNTNRLHTTFWPEEYPEIRDAADHIYLSQDLGMRKPEARIYQHVLQAEGFSPSDTVF
                     FDDNADNIEGANQLGITSILVKDKTTIPDYFAKLLC"
     CDS             20464..21309
                     /locus_tag="ctg1_3230"
                     /transl_table=11
                     /translation="MEKKFYIDWDNEISREEFINNILADEDLVKIRSLVISRWGECYEE
                     SCQPIIDMFAEHAERFAHLESLFVGDMESEECEISWIQQGDYSRLYAALPNLKKLTIKG
                     TQGLELGEIAHDKLEHLEIISGGAPCGVFASLQNSQLPALKTLIVYIGVENYGFDASLD
                     IVMNLASKSLFPSLTHLGLVNSEEQNEITRRVLESDIMPQLEVLELSCGTLTDKGAEHL
                     LKHADRLSHLKLLDLHYHFLTTEMRKKLQKTLTCTVELSEEQKVDDDDDDDYMYPMFTE
                     "
     CDS             21370..22356
                     /locus_tag="ctg1_3231"
                     /transl_table=11
                     /translation="VITLIGHPESKRTFYFCQAASCLQEHINVVSYDQALTLPLNKGMV
                     KIDPPLHQETDIRLINTVSQNYITFLQKMVNRREIRFINSPEGIINLLDKCHCKHRLIE
                     HAIPTPPILADDVRSYDQLIARMRSEKVYRVFIKPNFGSGAAGVLALSLHPGDNRQVLY
                     CAIQVAGNRLVNSKHIIRYENSDDITLIVNAILQQENIIECWLAKARVGNKSYDLRIVY
                     VNGEIVWRVVRTSSQPITNLHLQNEAIRFADLNLPAEKVTEIDTLCLNAMKLYPDVHIA
                     GIDVLLTQNLTPYIIEINGQGDLIYQDTCEQNIIYQRQIQVMREHHV"
     CDS             22349..23221
                     /locus_tag="ctg1_3232"
                     /transl_table=11
                     /translation="MYNVTDEVPENTRTAIHSCDGEINMNDLIAREANILFVVLDSLRF
                     DIAFQEQEAGNTPNINRYGRWIKCEAAGNFTWPSHHSMFSGFMPKPLEAAPGHSMLFFP
                     KDIGLGRLGPKNAFAFSEDTWIKGLENKGYRTICVGGVSFFNNRSGMGKVFPAMFKESY
                     WYPNFSCTVKESMDNQLTLINKKVNAEQPLMMYINIDTIHYPNHFYIENAKPGDTVETH
                     AAALHYIDARIEKLFDTFRQTGRETLVILCSDHGTCYGEDGKYFHSFNHPIVNTVPYFH
                     FVLDGKTDE"
     CDS             23202..24452
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3233"
                     /sec_met_domain="Radical_SAM (E-value: 3.2e-16, bitscore:
                     58.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKPMNNESIYQQYMYSYPHKTAYRELNNIAFADVKSRIYEHKTH
                     LYIHMPFCQSRCGFCNLFSCTGADNAFIDNYIEAIIVQARQMQLAPVDWASFTIGGGTP
                     LLLNVGQLSRLFSRVFDELQVDAQIFKAIETSPSDTTAEKVALLCQLAVNRVSIGIQSF
                     NDLELATLHRRHSAENAHRALELLRRGNFPILNIDIIYGIPGQTATSLMASLNQALDYQ
                     PDELFLYPLYNMPRQPDMYSLYIEARDRLLHEGYTQTSMRRFVRVNNESTAESCGFENS
                     LALGAGGRSYLGNLHYCTPWSQNQPASRQIVANFIARPDKTQIHHGYVLSQAEMKRRFI
                     IKNLFFYKGLSLSDYQHQFFSEVLSDFPLLGDFIKQDYCHQQDNRILLTVQGLALSDQL
                     GPQFISPEVHSLETHKR"
ORIGIN
        1 caaagccaca cttcacctgg cgggatgggg tgatgaggaa atgcaatcgg ccccctataa
       61 cattcagccc ggtgaaccaa cagaggcgca gtcacacatc agcactgacg gtacaatttt
      121 caccaccggt gacgccattc ctgtcaccgt aacgctgaaa gatgcgtggg gaaatcatac
      181 cccggggcag gcgtcttacc tgagtacaca tgtggttgcc gcccacacag tgccgcagcc
      241 cacgcagtgg caggaaaaca gcgacggcac ctacagtgcg caattcattg ccggtgaacc
      301 tggcacgggt ttacaggtga cattaaacca ggacagcggc tggaaggtcg cggcgatcta
      361 cagcatcatc gctggtgaac cggcaattaa taattccttc gttgatacgg ataaaaacaa
      421 ctatcaggcc ggtaacaata tgctcatcag cgtgaaactg gcagacagtc ggggtaacgc
      481 gctgagcggg cgggaagcca tactgaacga tgccgtggcg gtgggtagcg ccacccgcaa
      541 agagggcagc gtctggactg aggatacgca acacaaaggc acctacacgg cgtactacat
      601 ggcgcaacat gccgggcagg acagcgtgaa actgacgctg gatgatggtg caaaatcctc
      661 tgacgcctac accattgtgg cggccgcgcc agtcgacaaa aactccgcga ttcaacgtgg
      721 tgaggctgcg acctataccg caggtgacac cctgaaactc accgtgacac tacaggacaa
      781 ctggggcaac ccggtcagcg ggatggaaaa cgtccttgag ggcagcgtga cgttaccgga
      841 agctgaaatt caggaaagcg gctggcagca aacctcaccc ggcgtatatg aagcgaactg
      901 gactgcgcga atagccggtc cgtcgctgac agcgaagctt gagctggaag gctggcgtaa
      961 ggagacggcg ccttttgtta ttgtcgctgc cgggccggac tatgaaaact cgtccctccg
     1021 caccagcaac ttcgctttta cggctggcga tgatatcacc attacggtga tactcatgga
     1081 tgcgaatgaa aacccggtga ccggtgcaga aggtcttctc actaatgaga ccgttaaggt
     1141 accgggcgca acacgtaagg ggacggtatg gaccgataaa ggcgacggaa cataccgtgc
     1201 cgaatgggaa gcagagcaag ccggtaacgg atataaagcc acacttcacc tggcgggatg
     1261 gggtgatgag gaaaggcaat cggaccccta taacattcag cccggcgaac cggcagaggc
     1321 gcagtcgggc atcagcacgg acggggatac cttcgtggca ggtcaattca ttcctgtcac
     1381 cgtaacgctg aaggatgcgt ggggaaatca tgttccagcg caggagtctt acctggctac
     1441 gcatgtggtt gccgcccaca ccgtgccgca gcccacgcag tggcaggaaa acagcgacgg
     1501 cacctacagt gcgcaattca ttgccggtga gcccggggca gatttacagg tgacgttaaa
     1561 tcaggacagc ggctggaagg tggcggcgac ctacagcatc atcgacgcgc aaccggtaat
     1621 cgataattcc ttcgttgata cggataaaga cagctaccag gccggtgacg atatgctcat
     1681 taccgtgaaa ctggcagaca gtcggggtaa cgcgctgagc gggcgtgaag ccatactgaa
     1741 cgatgccgta gaggtgggta gcgccacccg caaagagggc agtatctgga ctgaggatac
     1801 gcaacataaa ggcacctaca cggcgtacta catggcacaa attgccgggc aggacagcgt
     1861 gaaactggcg ctggatgatg gtgtaaaatc ctctgacacc tacaccattg tggcagctgc
     1921 gccggtcgtc aaaaactccg cgatccaacg cggtgaggca gcaacttaca ccgcaggtga
     1981 caccctgaca ctcaccgtga cgctgcagga cgactggggc aacccggtca gcggcatgga
     2041 aaacatcctc agggacagcg tgacgttacc ggaagccgga cttcaggaac gcggctggca
     2101 gcaaaccccg tccggggaat acgaggcgaa ctggactgcg cagaaagccg gtacgtcgct
     2161 gacagcgtcg cttgagctgg aaggctggcg taaggagacg gcaccttttg ctatcgtggc
     2221 gggaacccct gtgcagtctg agtccagcct gcaaacggac aaggagtcat ataccgtgga
     2281 ggatactctg gaactgacgg tcacgctccg ggatgcctgg aaaaatccgg tcagtggaaa
     2341 actggccctt gtgaatgacg ctgtattgac aattgacgca gcctccgcga cagatgtctt
     2401 tagcgaaggc gataccgccg gtacgtatat ccgccatttt acgctgaaca gctggcgtga
     2461 cagcacgcaa gtgtccatca ggcttcagac atgggaccgt gatgcaacat cgaatccata
     2521 tagtgtagaa aggcggcggt taccgatgac tggaacgatt gttgccaacg acggtaattt
     2581 tgggttagat gaaggatttc cgaccacagg attcatcggc gcgtggttta ttctgagtag
     2641 tgatatgcaa atagagtatg ataaaacaac atgtggaggt aatgaaaata gttgcgactg
     2701 gctgcatgtg aatacaatgt ctcccaacag tcatgaagtg tcatttatcg gacaacccac
     2761 ttcagagacc cgcgaggtga caattaattt tatctcacta tccgacgata atattatcta
     2821 cacctacact tttaatttga cagcatggtt cagtactatt tctcctgttc aagatacccg
     2881 gcaacaggcg atagacaggt gtggtggcgc agagaacctg cctcttttaa aagatttgac
     2941 ttctgctact gccctgggac aaccagggat aagaggtatc ggtaatctgc atggtgaatg
     3001 ggggaatatt aatcggattt taaacacatc aattttcaat gtatggacca atgaaatatt
     3061 ccctccagtt tattattata tagtgaacgt ttcagttgga attcctaata tgcaatctga
     3121 aaatgcccat attaatacaa tatgtcgaac catcctttaa cggttcagga gcgcaaaggt
     3181 gcaagacatt acatatgcgg ttttgacatc atggtattca cagtaattta aaaggttaag
     3241 ccgcatacgc ggcttaacca acattctatc tctcactgaa aatcaacggt ttttaacgca
     3301 ggcggttata attaccgacc atttcgttat aagcgcgtaa tgattgcggg taagagtcct
     3361 gtaccatcca gcttgtgttt gcgtcctgaa gtgtctcttt atcccaatca gaatacggga
     3421 ctttatctct gatacgacga acatactttt tagctgcgag ttgatatcgg tctgctgcac
     3481 ctgtgaagag agaattcata ctgtctttac tcacttcttt ggcttgcgcc accagcgttt
     3541 caagttcagc cactttcttc attgccgctt cggcgtcaaa attctcttgc gaaatcattt
     3601 tattaatttg tttagctgaa atcatgactg ccagagaata gtagttaaaa gttttccctt
     3661 ctctttgttc aatatttttg agctcctcca gttggcgttt atcattaatt tcctgaatcg
     3721 ctgcatgata agattccgca accggctcga aggcttcgat attttttaca aatacctgat
     3781 gcagcgtttt accttttgca aatgcatcat ctttataatt ttcctaggtg taatatttat
     3841 ccatttcgtt aatggtatta cccagcgcta cagcagtatt aatataattc aacgccacgc
     3901 catcaatggg ttccagtgca ggcgttaacg ccactacgct ttttattcct ttttcacact
     3961 cagtgagatt ggattgacta atgctgtaga tcccataaac atggctctct ttacccgtcg
     4021 gcccctgttt aaaatctttc acccagtcaa cataacgcgc cagactgtgc tgcacaggaa
     4081 tttgtaactt attgtagcac ttgatataga cattcattgt ttcgttgtaa accgcttccg
     4141 catcaaccac tggttgggca gcggtttcag gtttagcttc tgcttttacg gccgtaggtg
     4201 cggctgattg actattggcg ggcggagggg tttgtgtttc agctttttta tcatcacatc
     4261 cggtcatacc gagggccatt atgccgataa caatagctga agctaataaa ttccttttca
     4321 ttcaattgcc ttataaatac atagataaga gagataatat cttaaatgaa aaaatgatcc
     4381 gtcactatac acattttgct tataaacaaa ccgaaatcat tcatggcccg aataattcct
     4441 gcgacataaa aatataaatc gcaggaagct attttaatta cccgctctac cactgttgca
     4501 ggatataaac tctcacctac attccataac gctcagcaat agcagcatgt ttctcttcat
     4561 tcgccccggc ttctttggca agacgccacc agcacaacgg atgttcccag tcagcggtca
     4621 attcgtgcaa gatcttgtcg atatcacctt tagaaactga acgcggtgca ctgataacaa
     4681 aatagaatgc aggcagcggt tcagcgcctt ctccttgatg actgtccgtt aacgtatagt
     4741 cgtcattact gttgctccag tagtaccagt ttcgttcacg gagcgcctca cggaaagtat
     4801 taaactcttc ttcaccaggc atgatacctt cgcagaacca ggactcgccg tattcggtcg
     4861 ggataatggt tttcaggcac ccataaagcg gagtgaaatt cttctgctct tcctcatcct
     4921 ctggtcgggt attcaacatt tctgcatcga ataccacaac ctcatcaaca tgttgcggat
     4981 aatcggtgcg gtaagttggc tcaatgatcc ttgctgttac cggcccaata cgttgagcat
     5041 agtaatagcg gtattcataa ttttcccgga agcggatgtt taacagcccc catttttcgt
     5101 caataaaacc ttcgccttcc gtgagctcga tttccagttc agcagcaata gcacgaacca
     5161 aatcccattg ttgcaggatg ctggcggtcg ccatgatatc ccactggaga ttgcgaatat
     5221 cttcttcacg gctaatcatc agttgctgca attgttgtaa ataatccagc tttcgatccc
     5281 aggcttcctg tttttgtgct gcccaggagc acatgcgata aacgccaacc cactcgcgcc
     5341 ctttttcgtt ttgcagcaac tgttgcccaa ttgcctccag tgcaacccag tcttcctgct
     5401 ggttaatcac ccgcgcacgg aaccacagcg ccatatgtag cagacccgcc tgttcataca
     5461 gcttcgccag gtgctcgatc gcctgctgat cgccacggtt aagcaagaga tccagtagat
     5521 caaagcacag gccgttatct tcctgaagat ggctttcaac atggcgttgc agaagttcaa
     5581 tcgactcatt aagcgcattg caggcgttta acgcattgac cagtttaccc agcaattccg
     5641 catcatctgg cgtgttcaga taggcgcgac ggaatatctc gacgtctttt tcgggatctg
     5701 gctgtgtttc ttcatcgctg ttttcaggta cttctacaac cggacgagca agcagttccg
     5761 cttctttggc ggcaattttt tcgctaagtt cgagaaactc gcgatcaacg cccagtaatg
     5821 cgcgtaattt tggcatgtgc tgctgggcca gtttcatcgc cattttggcc acccagacgg
     5881 attcgcgctc cagcgccaga gtgatttgca gttttgccag attcaccact ttgcggtgcg
     5941 ccccggcctg cgaacgttgc tccagcattt tttggatgat gcgtgccagc tgccagtgat
     6001 ttctctgcgg atggcgagga agcagtacgg taataatctt cacccacata ccccacgaat
     6061 agggggtcag atctgtccaa cgaggcagtt cctcccagac ctcttcgtcc tgcccacata
     6121 acgccatgat gtacagtttt ttgaggtgat aactgatgcg gtcacggccc cagtaatcgt
     6181 tctcttttgc cagttcatca atcacttcac gagcctcatc gtagcgctga agggcaacca
     6241 aaatatcggc gcgtattgcc agcagcgctt ctaaatattc actccccgat gctttcaccg
     6301 cctcgatttg cctgtcgata taaaccaacg cctcttctgt tttgttggaa tccaccattg
     6361 cactggcata ttcgcaggat aaacacataa agcagctcca ggtcggatca atgcgcgcga
     6421 tggtttcctc acatactgcc atgcgttcat tcgcccagcc tggtgcgtca atattttcgt
     6481 agcaggctga taaatcctgg gtaacgcaga tagattgcgg gcaatctttc gcctcttccc
     6541 gatgcgcttt ttcaaacagc gctaccacgt ctggcagcac cttttcacct tcttcatagt
     6601 tagtcaggcg atgacgcatt tcccagtgac caataaatat ttccagccac ggatttttgg
     6661 cgacttgatt cagtgctttc atttccggca atagcgaatc gcatttttct atttgtaggt
     6721 gcaaaacact ttctgaaaaa tcatcaataa gctgcggaat atattcttgc ccggcatcac
     6781 gcaactcttg actatatttg ttgtaccact cccatgtatc cattttattt tccttgatta
     6841 attaagacag gaataacctg agtaaaatct tccagtgcct ggtgtaaatc ccactgctgt
     6901 tctttattac cgctggagca caaaatcact ttcagcgatt ttaataagcg taatgccgct
     6961 gcgggctgtt gctggtgttg taatgccgtc accagttgca tgatgcaagg gttattaagg
     7021 ttgatgtata aacttgaggt tttcgttttt tggatttgcg aggtaaattg ccgcgccagc
     7081 attaacgctg cggtactgat gcgtttatct gcgttatcct gttcgagaat ttgttttaat
     7141 tctgcttcgc ggtctggcgt gaccactaac ggtaaaacgg cgggttcgaa gcgggagata
     7201 attaattgct cgccatcgca gagatgctct tccagataag ccacctgctc ttcgggtaat
     7261 tctgccaggc tgaacaactg ctcattgccc gtttgcgtac cgacttcgat aatccggcag
     7321 tgatataaca gcgcccagcg acgtaaaaat ggcacgacgg catagcgatc gccacgggca
     7381 acgggccgtt gcagaatgtg gaacaacatc tcttcaaaac cgccgtcgcg gcttaacaga
     7441 atatgaatgc tgttattaac gcgtaaatcc ttcgccagca acgccccttt tgacgttggc
     7501 acctgcaagc gatctttgag caaatcaaac agacggtcat cacacaatgc cgcaccgagc
     7561 aacgcttcgt tgtggcgcat taatacacgc cgccatattt ctggctgatt ttgtgcgaga
     7621 tcggacaaac cagaaatcag cgtctctttt aacgcctcct gcaccgcaac ccaggtttcg
     7681 tcccgctgga gatcttcccg gctcgccgtc ggcgttagtt tcgatgactc aatcacgccg
     7741 ccaataaatc cggcccaggg aggtaacaac tcacgcgctt catcatccag taacataccg
     7801 cgcaaaaaca gcgacaggtt gcggttatcg ctggtgccgt aggttgcgcc atcctgaatc
     7861 cataaaatcc caaccgcgtc gctcatcccc acgggcacca ccggaatggt gcaaatcggt
     7921 tcgaaggagg attcaaactg tgcggcaaag gcgagatttt tacgctgtac cagcgcgcgg
     7981 tgcatggtta cgccttcggg ggcaacttca cgccacggtg gttgcagttt attcaccggc
     8041 tcgctggcat caccgacata gactggttcg tgcagcaata tgcagtagcg ggaaagaacg
     8101 cggttcagca gattattact cgccagatgg ctgtactctt ctttgagcgt cagaatcacc
     8161 tgcgttcccg gcgccgagga ctgatgcggc gtaacggtgt atttttgccc gtcggtagag
     8221 tggtatttcc agctctgatc cggcgtttgc caggatgtgg tcaacaccgt gacctctttt
     8281 gccagtacaa acgctgacaa aaaaccgagg ccgaacatac caattaaacc ggtgttgtca
     8341 tcctgctggc gcaacattcg ggtataaccg acgccaaccg tggcaagaaa gccatgaatt
     8401 tcactttcag tgaggccagc gccagtatcg ctaatgatga tagtggactt cgccacgtct
     8461 gccactacac gaatttggtt atcctttggc gcatcgggct gctcaatcct gcggcgcacg
     8521 atcgcatcat ggccgttctg caccagctcg cgcacggcaa ccacgggagt ggagtaaaga
     8581 tgcttactga gcacctcaat taagccgttt aaattaactt ctgtagaata tgaactgcca
     8641 ggtaactgta atgtactcat ttttcaatac tcataatcca tcacctacta ttgaaaatac
     8701 attgctgttt tttacaaccg gtgcaaggtt tgttatttca ttcactcatc gaaaacattt
     8761 atttattgac gcgatgatta aaacaaaatg tcttatataa ataatgatta attcttaaag
     8821 gattaatgcg actggagtat atcgatataa accggagtta acgagataat ttcttgtggt
     8881 gaaattatta tttaaatgct gaataatata ttgaggatta tttaatagaa aaataaaacc
     8941 gcaatccaga atcagaattg cggtatttct ttaattatga atcaatcgct gcggatgagt
     9001 ataaaccgtt gcccgacccg gcttacaaaa gcccaccagc gtcaaattac agcgctcagc
     9061 cacttctacg gcaagcgtgg tcgcggcaga caccgcaaac aaaatttcta cgccgcacat
     9121 cgctgacttt tgcaccattt cataactggc acgactggaa accagcaccg caccttgctg
     9181 ccagctttcc ccttcttgtg accggcggcc taacagttta tccagcgcca catggcgacc
     9241 cacgtcttca tgcccgccta ccagttcgcc agatggcaac atccaggcgg cggcgtgagt
     9301 acaaccagtc agttgcccca ctggctggaa atcattgaga tggcgtaatg catcatccag
     9361 tttgttgaga tcaaacgcct gggtgaacgg cagcggctgc accggtttac cgatgtcgtt
     9421 aagttgctcc acgccgcaca cgccacatcc cgtacgtccc gccagtgccc ggcgacgctc
     9481 cttcaacccc ataaagcggc ggctggaaag ctcaatttgc acttccagac cattacagga
     9541 aggaacgaca tccataccga agatatcgcg cggactttcg ataatcccct ctgaaagcga
     9601 aaaaccgagc gcaaagtact caaggtcttt gggtgacgcc atcatcacca catgcgaaat
     9661 accgttgtag accagcgcaa cgggaacctc ttccgccacc tcatctatcc gtgggtgttg
     9721 taaatcatca cgccgccata actcaatttg acgaacacct gtgatatttg tcacattttt
     9781 gatttctttt tgctgtgttt ttttcacttt ctcttaacca gataagaaca cacacaccaa
     9841 cattatggta ttctgttaca aacccttcct ggatggaggg aaattgagcc aattctggac
     9901 ctttgcggcc ccttccgcaa agaaaaataa ctcccactcc ctgcacactc agcaagcgaa
     9961 tgtaaatggg acgtgacaat gtcgaaacaa ggagcaatcc atgcaggtca gcagaaggca
    10021 gttctttaag atctgcgctg gcggtatggc aggcaccacg gcagcggcac tgggttttgc
    10081 acccagcgta gcactcgcgg aaacccggca gtataaactg ctgcgcaccc gcgaaacccg
    10141 taatacctgc acctattgtt ccgtaggctg tgggctgttg atgtacagcc tcggtgacgg
    10201 agcaaaaaac gccaaagcat ctatcttcca tatcgaaggt gacccggatc acccggtcaa
    10261 ccgcggtgca ctttgtccga aaggcgctgg cctggtggat ttcatccact ccgaaagccg
    10321 tctgaagttc ccggaatacc gtgcgccagg ttctgataaa tggcagcaaa tcagttggga
    10381 agaggcgttt gatcgcattg ccaaactgat gaaagaagac cgcgatgcta actacattgc
    10441 gcaaaacgcc gaaggcgtga ctgttaaccg ctggctctcc accgggatgc tgtgtgcttc
    10501 cgcgtcgagt aacgaaaccg gctatttaac gcaaaaattc tcccgcgcgc tgggtatgct
    10561 cgcggtcgac aaccaggcgc gtgtctgaca cggaccaacg gtagcaagtc ttgctccaac
    10621 atttggtcgc ggtgcgatga ccaaccactg ggtcgacatc aagaacgcca acctcgtcgt
    10681 ggtgatgggc ggtaacgccg ctgaagctca cccggtcggg ttccgctggg cgatggaagc
    10741 caaaattcac aacggcgcga agctgattgt gatcgatcct cgctttacgc gtacggcggc
    10801 ggtggctgac tactatgccc ctattcgttc cggtactgac attgctttcc tgtcaggcgt
    10861 attgctgtac ctgctgaaca atgaaaaatt caaccgcgaa tacaccgaag cctataccaa
    10921 cgccagcctg atcgtgcgtg aggattacgg ctttgaagat ggcctgttca ccggctacga
    10981 cgcggaaaaa cgcaagtacg ataaatccag ctggacctac gagctggacg aaaacggctt
    11041 cgccaaacgc gataccacgc tgcaacatcc gcgctgcgtg tggaacttgc tgaaacagca
    11101 cgtttcccgt tatacgccag atgtggttga aaacatctgt ggtacgccga aagacgcgtt
    11161 cctgaaagtc tgcgaataca tcgcagagac cagtgctcac gataaaactg cctcgttcct
    11221 ttacgcgctc ggctggacgc aacactccgt tggtgcgcag aacattcgta cgatggcgat
    11281 gatccagcta ctgctcggca atatggggat ggcaggcggc ggcgttaacg ccctgcgcgg
    11341 tcactccaac attcaggggc tgacggacct ggggctgctg tcgcagagcc tgccaggtta
    11401 catgacgctg ccaagcgaga agcagaccga tctgcaaacc taccttgccg ccaatacgcc
    11461 gaaaccgctg ctggaaggcc aggttaacta ctggggcaat tacccgaaat tcttcgtctc
    11521 catgatgaag gccttctttg gtgataaagc gacggcagaa aacagctggg gctttgactg
    11581 gttgccgaag tgggataaag gctacgacgt cctgcaatac ttcgagatga tgaaagaggg
    11641 caaggtcaat ggctatatct gccagggctt taaccctgtt gcctcattcc cgaacaaaaa
    11701 caaagtgatc ggttgtctgt cgaaactgaa gttcctcgtc actatcgacc cgctgaacac
    11761 tgaaacctct aacttctggc agaaccacgg tgagctgaac gaagtggact cgtcgaagat
    11821 ccagaccgaa gtgttccgtc tgccatcgac ctgcttcgcg gaagagaacg gttcaatcgt
    11881 taactccggt cgctggttgc agtggcactg gaaaggtgcg gacgccccag ggattgcgct
    11941 gactgatggc gagatcctct ccggtatctt cctgcgcttg cgcaagatgt acgccgaaca
    12001 gggtggcgcg aacccggacc aggtgctgaa catgacctgg aactacgcca tcccgcatga
    12061 gccgaagtcg gaagaagtgg cgatggagag caacggtaag gcgctggccg atattaccga
    12121 tccggcaacc ggggcggtta tcgtcaagaa aggccaacaa cttagctcgt tcgcccaact
    12181 gcgcgatgac ggtaccacct cctgtggctg ctggattttc gccggtagct ggacgccaga
    12241 aggtaaccag atggcacgcc gtgataacgc cgatccgtct ggcctcggta acacgctggg
    12301 ctgggcatgg gcatggccgc ttaaccgccg cattctgtat aaccgcgcct ccgcagatcc
    12361 gcagggtaac ccgtgggatc cgaagcgtca gttgctgaaa tgggacggca ctaagtggac
    12421 cggctgggat attccggact acagcgcagc acctccgggc agtggcgtcg ggccgtttat
    12481 catgcagcag gaaggcatgg ggcgtctgtt tgccctcgat aagatggcgg aaggtccgtt
    12541 cccggaacac tacgagccgt ttgaaacgcc gctggggact aacccgctgc atccaaacgt
    12601 tatctcgaat ccggcggcgc gaatctttaa agacgacgcc gaagcattgg gtaaagccga
    12661 taagttcccg tatgtcggaa ccacctatcg tctgaccgag cacttccact actggaccaa
    12721 acacgcgctg ttgaacgcga ttttgcaacc agagcagttt gtggaaatcg gtgagtcgct
    12781 ggcgaataaa cttggcattg cccagggcga taccgtgaaa gtctcctcca accgtggcta
    12841 tatcaaagcc aaagcggtgg tgaccaaacg tattcgcacg ctgaaagcga atggcaaaga
    12901 tatcgatacc atcggtattc cgattcactg gggctatgaa ggtgttgcga aaaaaggctt
    12961 tattgccaat acgttaacgc cattcgttgg tgatgcgaac acgcagacgc cggagtttaa
    13021 gtccttcctt gtgaatgtgg aaaaggtgta acggagacga catatggctt atcaatctca
    13081 agatatcatt cgtcgttccg cgactaacgg tctgaccccc gcgcctcagg cgcgggactt
    13141 ccaggaagaa gtggcgaaac tcatcgacgt caccacctgt atcggctgta aagcctgtca
    13201 ggtggcgtgt tcagagtgga acgacattcg cgataccgtc ggcaataaca ttggggtgta
    13261 cgacaacccc aatgatttaa gcgccaaatc gtggacggta atgcgcttct cggaagtgga
    13321 gcagaacgac aaactggaat ggctgatccg taaagacggc tgtatgcact gttccgatcc
    13381 aggctgcctg aaagcgtgtc cggcggaagg ggcaattatt cagtatgcca acggtatcgt
    13441 cgacttccag tccgagcagt gcattggttg cggttattgc gttgcgggct gtccgttcga
    13501 cattccgcgc ctcaacccgg aagacaaccg cgtctacaaa tgtacgctgt gcgttgaccg
    13561 cgtggtggtt gggcaagaac cggcctgtgt gaaaacctgc ccgacggggg cgattcactt
    13621 cggtacgaaa gagtcgatga aaacgctggc gagcgagcgc gtggcggagt tgaaaacccg
    13681 tggttacgac aatgcgggtc tgtacgatcc ggcaggcgtg ggtggtacac acgttatgta
    13741 cgtgctgcac catgctgaca agccgaatct gtatcatggc ttgccggaga acccggaaat
    13801 cagcgaaacc gtgaaattct ggaaaggcat ctggaaaccg ctcgcagctg ttggctttgc
    13861 ggctaccttc gcagccagta tcttccacta cgtgggtgtc ggtccgaacc gtgcggatga
    13921 ggaagagaat aatctgcacg aagagaaaga cgaggagcgc aaatgaaacg acgtgacacc
    13981 atcgtgcgct acaccgcgcc ggaacgtatc aaccactgga tcaccgcctt ctgcttcatc
    14041 ctggcggcgg tgagcgggct gggctttttg ttcccttcct tcaactggtt gatgcaaatc
    14101 atgggcacac cgcagctggc gcgcattctg cacccgtttg tcggcgtggt tatgtttgcc
    14161 tcgttcatca tcatgttttt ccgttactgg catcacaacc taatcaatcg ggatgatatc
    14221 ttttgggcga agaatattcg taagatcgtc gtcaacgagg aagtaggtga caccgggcgt
    14281 tataacttcg gtcagaaatg cgttttctgg gcggcgatta ttttcctggt cctgctgctg
    14341 gtgagcggtg tgattatctg gcgtccttat tttgcgcctg ctttctcaat cccggtgatc
    14401 cgattcgcgt taatgctgca ttcatttgcc gcagtggcgt taattgtggt tatcatggtg
    14461 catatctacg ccgccctttg ggtgaaaggc acgattaccg ccatggtgga aggatgggtt
    14521 accagcgcat gggcgaagaa acatcacccg cgctggtacc gtgaggtccg caagacaacg
    14581 gaaaagaaag ctgaatgagt attcgcataa tcccgcaaga tgagctgggt tcgagcgaga
    14641 aacgtacggc ggatatgatt ccgccgttat tgttccctcg gctcaagaat ttatacaacc
    14701 gccgcgccga gcgtctgcgc gagctggcag aaaataatcc gctgggtgat tacctgcgct
    14761 ttgctgcgct tatcgcccac gcccaggaag tggtgctgta cgaccatccg ctggaaatgg
    14821 atctgactgc acgcattaaa gaagccagcg cacagggcaa gcccccgctg gatattcacg
    14881 ttctgccgcg tgataagcac tggcaaaagc tgctgatggc gctgattgct gagctgaaac
    14941 ctgaaatgag cggcccggcg ctggcagtga ttgagaatct ggagaaggca tcgacccagg
    15001 agctggagga tatggccagc gcactgtttg cctctgattt ctcgtccgtc agcagcgata
    15061 aagcgccgtt tatctgggct gcactgtcgc tctactgggc gcagatggcc aatctgatcc
    15121 ctggcaaagc ccgcgctgaa tatggcgaac aacgtcaata ttgcccggtt tgtggttcta
    15181 tgccggtgtc cagcatggtg caaattggca ccactcaggg tctgcgttac ctgcactgca
    15241 acctgtgtga aactgaatgg cacgtagtgc gcgtaaaatg cagcaactgt gaacagagcg
    15301 gcaaactgca ttactggtcg ctggatgacg aacaggctgc gattaaagcc gaaagctgcg
    15361 atgactgtgg cacttacctg aagattcttt atcaggaaaa agagccgaaa gttgaagccg
    15421 tggcagatga cctcgcctct ctggtactgg atgcgcgaat ggagcaagag ggctatgccc
    15481 gcagttccat caacccgttc ctgtttccgg gtgaagggga gtaatctctg acgttttccg
    15541 ggtggcgcag gtcgcccgga ttacagttca tagggtgtga ttacacctgc tattcccgca
    15601 aaatctctcg tatttcgcgt tggcagttca agaccatgcc gccagtgcct gtttgacctc
    15661 gtttttccct ccaacacagc gataaggtta ttggtatgtc actgatgaca agcgtaggat
    15721 tgcctgatgc gctgcgctta tcaggcctac caataaactg caatatatta aattttcacg
    15781 actttgtagg acggataagg cgttcacgcc gcatccggca tgtacaacgc gcactttgtc
    15841 agtaatctga ttggtatcat ttttgccatt accactcctc gcgcagttta cgctgatatt
    15901 cgacaccatc ttcctccccc ttttgcctgc ctccctttgc tttacgcacc ggaaattgct
    15961 gccgctccag atattgctct accgcttcgc gtaaaattgc ggaccgtgaa accttacgcc
    16021 aacccctaag cttgttcagc cgtttaattg cctcttctga taaatgaaga aaaaccgtat
    16081 tcatcgccat cgttaccacc ttacatatac tgttcattaa tatatgtgta aaaattacac
    16141 cggaaaatta attaacgaaa gctggtttct gcatgtggtt ttatttttgc gagactcttt
    16201 ccaaaaataa tgcaacagtt acagttattt taatttttat taaaaaatgg tttagcatcg
    16261 cccataatta tttattactc ttgattagat gggggtcgct cccacataaa agtaataata
    16321 agtgataaga attaattatg gatggcatga atatatttat ttgttcagtt ttgcataggt
    16381 cttcatttac atcatccgga tggtatatcc gaaaaaagtc agcatcttta cagcaccaag
    16441 gtttaaggtg aaatctacca tccataactg accggtcagt gccgcaccaa ccggtcttta
    16501 attgttagta gtagtaaatt tgtggataac agtccgggaa ccagacgatt ccttgcggat
    16561 catccccctg cattacccga taacattggc gtcgatcatc tgcgcgacgg cgaagcgtag
    16621 tatagagtcg cttccattca tgatcgcccg gtgtactgta gtttacccag caatccattg
    16681 aagggtgacg ccatttacct gtaagtgttg ggctccctga atgcttatgc ggcttcgctt
    16741 taccattacg atcccggtct ttacgcgtat taaatgtgga catttttagt ctcctgttaa
    16801 gagttctaaa aatgtgcttc cttaaaataa ttcatcattt tcccttaatt cgcatagcgt
    16861 gcttttgcac gaatttccga tacgcgggaa ccattatgat agcgtcgatg tccacacatc
    16921 caacaagaac acatacaggg agtacgaaag caaacacctg atgctttttt gcttccgtcg
    16981 cctgctgtgc gataacgacg gcggattttt tttaatcgcg ccatatgatg gcgacgttca
    17041 gcacgattac gggtcatagc aatactcctg agcaggcggc actatgccgc tttcatagga
    17101 attctgaatg ctggtgcttt ctgtatggca taaccatgcc tctaacggtt aagtgcttgc
    17161 agcacatgtt gcggatcgtt ggcaatcgct cgcagcaaag cctttgcagt caagtaaaac
    17221 gccccttact cttcttcgtt cccgccctct tcatacgggc caaatggctt cgcgggcaga
    17281 acgatatacg taccttcaaa cactgcaccc ggcgtctcgt cgccaaagat ttcgacctgc
    17341 atctgcaccc gtgcttttcg tccgcgcgcc agacggtcga gatcgccact taaggcaccg
    17401 aggtcggcta ccgcatgagg tttgccgcta atcggcttgc tgtagcggat atgcgcatcc
    17461 gccagaataa tcgttccgcc gaggtggcgt tcacgcagca tcagccagat aagcccccaa
    17521 ccggtaagcg ttgccagtga gaataaactc ccggcaaaca acgtatggtg cggattctga
    17581 ttcccggttt ccggcatggt ggtgataaat ttttgcccgg tatattgctg aatgcgcacg
    17641 cccatttttt cactaagcgg gatgtgttca taccacgcct gttgcagctg cgcgcaccag
    17701 tcgccgcgat gcagaatatc atccagagtg gcgacgggtt taatcatcaa aaaatgacga
    17761 atcggcgtgg tggttggtgt ggtgatttct ccctgattaa cgaaccccag cttggcgaaa
    17821 aactccaccg cgtcttcacg ggcgctacag gtcacgcgct taacgccttc ctgacgcgcc
    17881 accgactcca gagtcatcgc catcagcgtt cctaaccctt tgtcctgcac gtcgggatga
    17941 accgccataa agcggatgga ggcttcgtta tcggcattga tatacagccg ccctaccgcc
    18001 accagatttc cctgctcgtc gacgaccatt tggtgatgcg ccatcgcatc ccacgcgtcg
    18061 cgttccgaac cttttggttg atgcaggggc ttacgcaaca tttcccagcg aaactgatag
    18121 taacgctcta attcttcttc tgtttgtgga acccgaaggt gatacatagc gatactctct
    18181 cttgtttccc gtgacaaccc tggaagctgg ctcatacctg caaccagaat gtcacggggc
    18241 catcattgac cagcgatacc tgcatatcgg cagcaaagcg tcctgtttgc gtgttcatct
    18301 cttgctgacg gcagcgttcg acgaaatagt catataacgc ctctgcgcga tccggtgatg
    18361 cgccttttga gaagcttggg cgcatccccc gttcggtatc tgcggcgagg gtaaactggg
    18421 aaaccaccag cacactgccg cccgcctgtt gtacgttgag gttcatcttg ccttcggcat
    18481 cgctaaagat gcgatagccg agcacacgct cgcacagacg gtttgctttc tgttcgtcgt
    18541 catccttttc gacacccaat aaaaccaaaa gtcccgcacc aatttcgccc gtcacttctc
    18601 cctccacggt gacgctggca cgggttacgc gttgaattaa tgcaatcatg gttcgtcgtc
    18661 ttcttcttgt tcagctgctt gttttagttt gcggtattcc ccgagagtga cagtaatttc
    18721 cgcgccaagc aagacgatac accacgtcca gtagacccag acgaagagaa tgggtatcac
    18781 cgccagcacg ccgtaaatga gctgatatga cgggaacatg gtgatataaa gcgcgaaacc
    18841 tttctttcct gcttcgaaca ggagtgcggc gacaaacgcg ccgacaatcg cgtcgcgatt
    18901 cggtacgcgg atggtaggaa caatgctgta cagcaaccag aaggagatcc acgacaacag
    18961 cagcggaaaa atacgcagca cattgtcgat gaccgtattg agatcgctcg cccaacgcag
    19021 ggagagcaga taggaactga tcgccagact ggcccccgcc aacagcggcc ctaacgtcag
    19081 gatcatccag tacacagcaa aagagtaaat ttttggccgt acccgtttac ttcgccagat
    19141 ggcattcaat gcgctatcaa tggaatacat caacaataac gccgtgacga tcaggccaca
    19201 tgccccgacg gcggtcatct tgttggaatt ggcaacaaac tgttcgatat attgctggat
    19261 aacgtcgcca gtggcaggga gaaagttggc aaaaataaag tgacgtagct ggatactaac
    19321 gtctgagaac atgggaaaag cggcgaaaag cgcaaaaaca acggcaacca gcggcactaa
    19381 tgagagtaac gacacatagg caagattacc tgccagggtt gtcatgttgt cctcatcaat
    19441 gcgttgccag agtagtttca gccaggccca tagcggacgg gtatgatgcc tggctttttc
    19501 atggatggtt tttagcataa caacttcgcg aaatagtccg ggatggtggt tttatctttc
    19561 accagaatgc tggtaatgcc cagctgatta gctccttcta tattatcggc gttgtcatcg
    19621 aaaaagaccg tatcgctggg tgaaaaacct tccgcctgca aaacatgctg gtaaattcgt
    19681 gcttcaggtt tgcgcatccc cagatcttgc gacagataga tatggtcagc agcatcacga
    19741 atttccgggt attcttccgg ccagaaggtg gtatgcaggc ggttggtatt ggaaagcacc
    19801 accacgcgat gcccctgctc acgcagttta tgcatgacgg cgatcacttc cgggcgcagc
    19861 gcaacaaaca ccgcctgcca gccgtgagag aactgctcgt agcttagcgg tagagccatc
    19921 tcatggcaca gcgcctctgc gaacgcttcg tcactaattt ccccacgctc atgctgatga
    19981 aacgcctccc ccatatgaaa actcttctta agcgatgcca gcggaacacg cgttaaatcg
    20041 ctccaggttc ccagcacacg gttaaagtcg atatcgacaa tgacattacc taaatcaaag
    20101 atatagagca tttttgcctc ctttcacacc ataagaaatt aactgtagcg ggaaaggtga
    20161 agtttggcta tgcagtcagg catgaaggct tgcaagtggt cacagaaaat taatggttac
    20221 cgtttcacta tattctcaat aattcgtgtc gcagcacatg caacttgaag gatgacgagt
    20281 atctgtgatg gctttatata taatgctgtc attaagagtt ctttttaaga aatcacatat
    20341 ttacttcatg aattaatatt attaatacat tcaaatagaa aatacatcca aaaaataaat
    20401 tctcaatgaa attaaaaaat attcagcgta ttatttctcc gccataaaat aaggatacat
    20461 accatggaaa agaaatttta tattgactgg gataatgaaa tatcccggga agaatttatt
    20521 aataatattt tagctgatga agacctggtc aaaattcgct ctttggtcat tagtcgttgg
    20581 ggggaatgct acgaggaaag ttgccaaccg ataatcgaca tgtttgctga acacgctgaa
    20641 cgctttgctc atcttgagtc cctgtttgtt ggcgatatgg aaagtgaaga gtgtgagatt
    20701 tcatggatcc aacaaggcga ttattctcgt ctgtatgctg cgctgccgaa cctgaaaaag
    20761 ctgacgatta aaggtactca gggcctggaa ctgggagaaa tcgcccacga caaactggag
    20821 cacctggaaa tcatctctgg cggtgcgccg tgtggcgtgt ttgcgtcatt gcaaaactct
    20881 caactgcctg cgttaaaaac acttatcgtt tatattggcg ttgagaatta tggttttgat
    20941 gcatcgttgg atatcgtgat gaatctggcg tcgaaatccc tcttcccgag cctgacgcat
    21001 cttggcctgg tgaacagcga agagcaaaac gaaatcaccc gccgcgtgct ggaaagcgac
    21061 attatgccgc aactggaagt gttggagctt tcctgcggta cgctcaccga caaaggtgca
    21121 gaacatcttc tcaaacatgc cgatcgcctt agccatctga aactgctgga tttgcattat
    21181 catttcctca caacagagat gcggaaaaaa ctgcaaaaaa cactgacttg tactgttgaa
    21241 ttatcagagg agcagaaggt tgatgatgat gatgatgatg attatatgta tccgatgttt
    21301 accgaataaa tgaaatttat tgggagagag tcatctctcc cattatttat cacagaaaag
    21361 gaattcttcg tgattacgct aattggtcat cctgaaagca aacgcacttt ttatttttgc
    21421 caggcagcgt catgcttaca ggaacatatc aacgtggtga gctacgatca agcacttacc
    21481 ctgccgctaa ataaaggcat ggtaaaaatt gatcccccat tgcatcagga aacagatatt
    21541 cgcttaatta atacggttag ccaaaactat attacttttt tacaaaaaat ggtgaacaga
    21601 agggaaatcc gttttattaa ctctccagaa ggtattataa atcttttgga taaatgtcat
    21661 tgtaaacacc gattaatcga acacgcgatt ccgacaccgc cgatattagc ggatgatgtc
    21721 cgtagttacg atcaactgat cgcccgtatg cgcagcgaga aggtttatcg cgtgtttatt
    21781 aagccaaatt tcggatcagg ggccgctggg gtgctggcat tgagtttaca tcccggcgat
    21841 aaccgtcagg tgctttattg cgccatccag gttgcaggta acagactggt gaacagtaaa
    21901 cacattatcc gctatgaaaa cagcgatgat attacgttga ttgtgaatgc tattttacaa
    21961 caagaaaata ttatcgaatg ctggctggca aaagccagag tgggcaataa aagctacgat
    22021 ttacgcatag tatacgttaa tggcgaaatc gtctggcggg ttgtcagaac atcatcacag
    22081 ccgatcacca atttgcatct acaaaatgaa gctatccgtt ttgccgatct taatttacct
    22141 gcagaaaaag ttactgaaat tgacacgctt tgtctcaacg ccatgaaact ctacccggac
    22201 gtacacattg ccgggattga cgtattactc acgcaaaact taacccctta tattatcgaa
    22261 attaacggcc agggcgatct tatttatcag gacacctgcg aacaaaacat aatttatcaa
    22321 cgccagattc aggtaatgag agaacaccat gtataacgta actgacgaag taccagaaaa
    22381 tacccgcacg gcaatccatt cctgcgatgg cgaaatcaat atgaatgatt tgattgccag
    22441 ggaagccaat atcctgtttg tggtgcttga ttccctgcgt tttgatattg catttcagga
    22501 acaagaggcg ggcaatacgc cgaatattaa ccgctatggc cgctggataa agtgcgaagc
    22561 cgctggcaat tttacctggc cttcgcatca ttcgatgttt tctggtttta tgcctaagcc
    22621 gctggaagca gcaccaggtc attcaatgct ctttttcccg aaagatattg gcttagggcg
    22681 tttagggcca aaaaatgcat tcgcattcag cgaagatacg tggattaaag ggctggaaaa
    22741 caaaggttac cgcactatct gcgtgggtgg cgtctccttt tttaataacc gttcagggat
    22801 gggaaaagtg ttcccggcga tgtttaaaga gagttactgg tatcctaatt tctcctgtac
    22861 ggtgaaagag agcatggata atcagctcac cttaattaat aaaaaggtga acgctgaaca
    22921 gccgctgatg atgtatatca atatcgacac cattcattat ccgaatcatt tttatattga
    22981 aaatgccaag cctggcgata cggtagaaac tcacgccgct gccctgcatt atattgatgc
    23041 gagaatcgaa aaacttttcg acaccttccg gcaaaccgga agagagacgt tagttattct
    23101 ctgttccgat catggcactt gctacgggga agacggaaaa tatttccaca gttttaacca
    23161 tccgattgtg aataccgtac cctattttca ctttgtgtta gatggcaaaa ccgatgaata
    23221 atgaatcgat ttatcagcaa tatatgtaca gttacccgca taagaccgct tatcgggaat
    23281 taaacaatat tgcttttgcg gatgtgaagt cgcgtattta cgagcataaa acacatctct
    23341 atattcatat gcccttttgc cagagccgct gcgggttttg taatctcttt tcctgcacgg
    23401 gagcagacaa tgcctttatc gacaactaca tagaggcgat tattgtccag gcccggcaaa
    23461 tgcaacttgc gcctgtagac tgggccagtt ttaccattgg cggcggtacg ccattgctgc
    23521 ttaatgtcgg gcaactgtcg cggttgttta gcagggtgtt tgacgaatta caagtcgatg
    23581 cgcagatttt taaggcaatt gaaacatcgc cttccgatac caccgccgaa aaagtcgcgt
    23641 tgctgtgcca gcttgcggta aaccgcgtca gtattggcat tcagagtttt aacgatctgg
    23701 aacttgccac attacaccgc cgccatagtg cggaaaatgc ccatcgggcg ctggagctac
    23761 tgcgcagggg taatttcccg atactcaata ttgatattat ttacggtatt cccggtcaaa
    23821 cagccacaag tttaatggcg tcacttaatc aggcattaga ttatcagcct gacgaacttt
    23881 ttttgtaccc gctgtataac atgccgcgcc agccggatat gtatagcctc tatattgaag
    23941 cccgcgatcg cttattgcat gaaggttata cgcaaacgtc aatgcgccgt tttgtgcggg
    24001 tgaataatga gtcgacggct gaaagttgtg gctttgaaaa ttcgctggca cttggcgcgg
    24061 gcgggcgcag ttatcttggc aatttacatt actgcacgcc gtggtcgcaa aaccagcccg
    24121 catcgcgaca aattgtcgcg aattttatcg cccggccaga taaaacccaa attcaccacg
    24181 gctatgtcct ttcacaagca gaaatgaagc ggcgttttat tatcaagaat ctctttttct
    24241 ataaaggact ttcgttaagc gattatcagc accagttctt ctctgaggta ttaagcgatt
    24301 ttcccctgct gggagatttc atcaaacaag attactgcca ccagcaggat aaccgcattc
    24361 tgctcaccgt gcagggttta gcgctttcgg accagcttgg cccgcagttt atttccccgg
    24421 aagttcacag tctggagacg cataaacgat gacgctcaag cagatccaga cgctgattta
    24481 tcgcggcgag ataaagtcgt gtaattatcg ctgtggttat tgcccttttc ataaacaaga
    24541 ccgcaatgat aaacagcagg atgaagtggc attatggcgc atggttgaac atttaccg
//
