LOCUS       NZ_AP019846.1          25386 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AP019846.1 Leptotrichia hongkongensis strain JMUB5056 chromosome,
            complete genome.
ACCESSION   NZ_AP019846
VERSION     NZ_AP019846.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:54:50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1670658
            Orig. end    :: 1696044
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25386
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1680658:1686044]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15386
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
     cand_cluster    1..25386
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="chemical_hybrid"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..25386
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /region_number="3"
                     /rules="(minimum(3, [AdoMet_dc, Amidinotransf, Arginase,
                     OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(244..2136)
                     /locus_tag="ctg1_1611"
                     /transl_table=11
                     /translation="MIFQNKKFSILFMFMVMFLFNSSRLDAVILHSEKIRNYEVTVQIN
                     KNGTLTVNEVIDYQFGEEFKHGIYRDIPLRSKRFGFDVHKSFIKMNWIKRDGKDEEYTK
                     NHFYEGIRYRIGSETELVNLYKTESVYELNYDIYNAVFEKDGIYQVYYNAIGQFWNVPI
                     EQASVIIRFPDGQKIKKNEIEKLEVYTGSYGEKGENYDILENDEEIYISIKELEAKNGL
                     TFMLNLKTDKISPTLVDKLKIVYLSNPAIIILPFLLLFLTIYSIVTWKFFGKDPQGKSV
                     IPEFNLPKDISPMFAAYINGERDTVEILNAGIFTLLTKGFIVANRVNGEIKYNKESKTA
                     YTQETELAEEERMLLDALSSEKNDIFGSEKRIYNKANSIIEILKDKYHKIIYKNNGSFL
                     VPFYCTAPVFMIFIFSQTNFEIFNTFIILYILITLGSFFHRIWITVSKKLLIGLLIIVI
                     LGVSFYQGIEIFVFTTYFVILFIVYAKLIGKYTNEGLRKKEYLKGMKMYIKTAEENQIR
                     KFDNVKELIEYFNGILPFAVALGVKNEAIKLMKKTIKIYNFDINESYINSHTHIYAYSN
                     HSFTNAFSRSYSSGKSKIMSEKFSSSKSGSGGGGFFSGGGFSGGGSGGGGGGSW"
     protocluster    883..25386
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1681540:1686044]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      10883..15386
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
     CDS             complement(2243..4195)
                     /locus_tag="ctg1_1612"
                     /transl_table=11
                     /translation="MKSFSNRKLNSIFSIMFVFFTLFFLSAKSLIAEKITNYEVTVQMN
                     KNGTLTVNEVIDYEFDGAAKHGIYRDIPLRSKKNGVDIYKSYIKMNSIKRNGISEEYST
                     KLFDEGIRYRVGSADRFVENGVNRYEFNYVIYNAVFEKNGIYQVYFNAIGQFWQVPIEK
                     AAVNIKFGNGEPVLKNEIRQLDIFTGEYGQSGKDYITNLNNGTVEIKTNKVLEAYNGLS
                     FRLNLKTDNISPTFWDKLQTLYYAHPLIAVGPIIIIILAIYGFVTWYIFGRDVNKKAIV
                     PEFNIPKDISAMYAAYINGEREPKEILTIGVLSLLSKGYVEANDEEGNGRNVEYTLSDS
                     RKSKPELAEEEKIVFNALSDNGYIFKKERSLYDASNKILKSFEKEYKKKVYKDNNIFNI
                     VFIVGMIIVFMISSTASSGTAGISDGISGAVSLVMVAIFFGIVLNTIFSIINNIYGNNS
                     KFLKIIKWIAVLFFSLIYGVLNFIIIGIIMAMYVVYSKIIGRYTVDGMRKKEYLDGMKM
                     YIKTAEANQIMKFNDVDELVAYFKGILPYAVALGVKNEAVKLMKNTIKLYDFDESTYSY
                     INRGVHFNSYNNFFLSDMISRGYNNAYNEIAEERFSTLRENSRNSSGSGFGGGGFSSGG
                     GFSGGGSGGGGGGSW"
     CDS             complement(4182..5492)
                     /locus_tag="ctg1_1613"
                     /transl_table=11
                     /translation="MEISLTQIIILLIMLITLVIYSYITWKKFGKNSVDEIISVSEPPK
                     EISAMMAAYMDGSKQTIDLAYLGLLELISKEFVIIEDYVDLKNYKVTEDEHEIKKDKKT
                     VEIVDIKKYYRQITKKKYGFNMGKINDYGCRQWELSEEERMILEFLIEYDKESILGYKN
                     PIMNQLLKILEVLKEKFDGRGNYAFLYLIGIKSINREKWDKRFYNSNWKLKILYIIIIF
                     LFGILLFIFEGMNAIVPLIVLFPTFFWAILLSNILFLILKTKGFPVLIKLMISLLIGVF
                     CGIVYFSAGLMLFPFGIAGVIITLVTILLVLYFRNIGKFTDGGARIKKDLEGFKMYVKS
                     GEVKKFNDVEELISYFKKILPFSQALKVQKHVVEMIKKSIEISGLEDKKEYIENTLNIF
                     IYKNDKFMKSFGNEIFAKEILEKASNEALEGNYYEEF"
     CDS             complement(5530..6096)
                     /locus_tag="ctg1_1614"
                     /transl_table=11
                     /translation="MSIVFILIGILVVLVVVGMGIYNKYIRLKNLNEEGWSGIGVYLQK
                     RLDLIPNLVNTVKGYATHEKETLENVVKLRSQMMSIDTKDIDNIEKIQKLENEMTKTLR
                     SIMMLQENYPDLKANENFLSLQSQLTQIETEIQSSRKYYNGTARDRNTFVETFPNNIFG
                     GIFGFKKAEFFNAVEGAEKAPEVKF"
     CDS             complement(6113..7285)
                     /locus_tag="ctg1_1615"
                     /transl_table=11
                     /translation="MKKINKIILFLFLLTIVQLFSSQYFKTIRITGKSAYKQFFLTEDI
                     YENSKNNLGDIRIIDKNGKEVPYVIETGKEQEKHSEKIVARAKIDEVLTKKDKMEFIVK
                     FNSDSLLKDIIGNRLALIPSKNFYTEYTLLGSNNGTDWEQITSGEIYKTPDKSNLTIEF
                     SEKRYEFYKIVTPLDKGNIFSEAILKLSNNEAGKLKTVGIKLDYKIEQEGKSTILKIKS
                     KFLPLKNIVLDVNDEFQRNYTVRSGDNFYAEGIISKVGEKSNLIINLENVPKLSEIIVE
                     IQNGDNSPLKINEVTGNYVPDRIVFRATEGEDYKITFGDESLDKPKYDIAEFADSIKER
                     DEVFVGKLEKADEKKVSKPRDYTVYYNVFIGVVVVILIGFMVNKINKNKK"
     CDS             complement(7269..7811)
                     /locus_tag="ctg1_1616"
                     /transl_table=11
                     /translation="MDILIERVAISYIFPFFLPILINIYLFMVAKNDIHLCFFKKNEKK
                     PLWILGESIYFLCVANIILRIYEDSGVLILGAGLALDIVGLLLCGYLVWKGFRVPNRNV
                     RRIGLGIGIFFVAKSFLWDFLRFDNSYKLIAYFSMGAILIGTSYIYQTALKKLEQEVKE
                     SLSDKNFGKGEKNEENK"
     CDS             complement(7898..9865)
                     /locus_tag="ctg1_1617"
                     /transl_table=11
                     /translation="MIDKLKELENLENKYKEIGRINSEIELIIANIKNEAGISREKELL
                     EENERLVKDLKAFHEKVKIREEEIGRLKNSNAVLIEELKEAKKVRRNGEIDKFQNILAA
                     KMNVELESGVTRRLSNYAEEMKRKVKMLERNLSHEFSDEADSLRDELKKINGKIGDFLE
                     KSNRKTFENKVFLQEESSVFHNKIKEETALKEGEILFEREKKRFVFEKLIGLKGFNFLG
                     IISIFLGVFLVFRTQFVKILSNNYVKSSASYLLGMFFLFAGEKFYQKNKKHFAVGLIGG
                     GIGILYLTTLLSTLYLKLYPMTAGLFISVILTGLVVILSLRYDSQIIGVLSLIGGYLPY
                     GAYIWVNKSNVQIYYVLAYSLILQGIVLGVSWKKDWIYSKIFGFVTGVVNMTGLVYYLN
                     HSIHDKITAFFYIIIFTTAYSFIFLNSHKKENRQSNIIDYIFLSLNLIIKFSLIYSLFD
                     KATPSWLKAVLVGTVGIIYGFFGDRLKDNKVAKIFYIVALGSFILIIPLIVPEKFVVVA
                     WGAETALLYFFYRKYKNKEMRYGTIAIYLVSLVSNLIVREEKYLLVYIQDLMIISFSFV
                     LYFLIKQKSYKTEVRILNGIFKYLIFTYSIFFINKVVFNVVTSFKMINYGENIFLSLLV
                     SLFVLRTVTCKAKNYKIVLI"
     CDS             complement(10001..10852)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Arginase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1618"
                     /sec_met_domain="Arginase (E-value: 1.6e-77, bitscore:
                     257.7, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNKNIHTFIGCDNEYNESKIAIFGAPFDSTTSFRPGTRFASAVM
                     RNESFGIETYSPYQDKDLEDIKVFDGGDLELSFGNSESALQDIQDETAEILKDGKIPFM
                     IGGEHSVTLGAVRAVAEKYPDLHIIQFDAHTDLRDEYLGQYYSHASVIRRCWDIVGDGR
                     IFQFGIRSGERDEWKFAKEHLHTTKFNFDGLDEVVEKLKGKPVYFTLDLDVLDPSEFPG
                     TGTPEAGGVTFVELHKAIEKISQLNIVGLDMNELSPVYDQSGQSTALACKLLREILLFI
                     YK"
     CDS             complement(10883..11725)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1619"
                     /sec_met_domain="Spermine_synth (E-value: 3.6e-58,
                     bitscore: 193.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 3.7e-18,
                     bitscore: 62.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYTEEHTKNVRFSIKIDKQLVSAKSDFQRIDIFESPEFGRFL
                     TLDGFMMLTEKDEFIYHEMITHVPMAVNPKAKKILVIGAGDGGTVRELIKYEHIERIDM
                     VEIDKMVVDLCREYLPKTANKLDDKRVHIYYEDGLKFVRSKANEYDIVIVDSTDPFGPG
                     EDLFTREFYGNCFNALKEDGILVNQHESPYYEADAKATARANKQLRAVFPFATVYQLHI
                     PTYPSGHWLFGFASKKFNPVEDLKADEWNKFGIETKYYNTELHKGAFALPNYVKDLIK"
     CDS             complement(11865..12395)
                     /locus_tag="ctg1_1620"
                     /transl_table=11
                     /translation="MADSRFLKFFNYILLVEGSYSNDKNDKGGETKYGITKERARECGY
                     KGSMKDLTKAMAQKIYEEKYYKARKLDQVKNDKVALSIFDFSVNAGRYGIKKAQEAVNK
                     VYGKNVISVDGAVGPMTLKYLNEVNPAKFLMVYHNLQREYYKSLAKNNVTQNDFLAGWL
                     NRVKVKENYLRNV"
     CDS             complement(12469..13932)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: OKR_DC_1_7_arginine"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1621"
                     /sec_met_domain="OKR_DC_1_C (E-value: 2.3e-12, bitscore:
                     44.4, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 4.3e-139,
                     bitscore: 460.5, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKNIDTDRQNKTVLFDALKNHLSNRVVRFDVPGHKGGRGNKEFR
                     DFIGLDAMQMDVNSMKPLDNLCHPTSVIKEAQDIAAEAFGAKEAYFMVSGTTGAVQAMI
                     MATCKAGDKIIIPRNVHRSAINAMVICGAIPVYINPGLNKKLGISLGMSINDVKKAIQE
                     NPDAKAILVNNPTYYGICSDLKSIVKLAHENDMFVLVDEAHGAHFYFDENLPISAMEAG
                     ADMAAISMHKTGGSLTQSSILLSGERINADYVRQVINLTQTTSASYLLMTSLDVARKNL
                     AINGRELFEKTVKFAEYARNEINKLGGYYAYGKELIDGDSVYDFDTTKLSVYTKDIGLA
                     GIEVYDILRDDYEIQIEFGDLGNILAIISAGDRGLEIERLISSLAEIKRLYSKDSTGMF
                     DHEYINPDVVLPPQKAFYSEKEMIPIKESAGKISGEFVMAYPPGIPILAPGERITEEII
                     NYIEYAKEKGCLLTGTEDMHVEKINVVLE"
     CDS             complement(14523..15386)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: AdoMet_dc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: AdoMet_dc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1622"
                     /sec_met_domain="AdoMet_dc (E-value: 4e-29, bitscore: 98.0,
                     seeds: 266, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNELENNKIKLYGFNNLTKTLSFNIYDICYAETEREQKDYIAYID
                     EQYNSERLTKILIRVAEMIGAQVLNISKQDYEPQGASVNVLIAEERISPENIDKSCNRG
                     KPFFEEIGMDENSIKKGGASQDTDTVHAHLDKSHITVHTFPEYHPDNSISTFRVDIDIA
                     TCGEISPLNTLNYLIDSFDSDIITIDYRIRGFTRDISGKKFFTDHNITSIQDYIEPEKL
                     KIYDAIDVNVYQSNIFHTKMLIKEIRLQNYLFNQDVYEIAPKKRLEITDRLRKEMIEIY
                     SGMNIY"
     CDS             complement(15750..15992)
                     /locus_tag="ctg1_1623"
                     /transl_table=11
                     /translation="LDQELYNSIKISDRKITYIEEFEGKYFIGLENGELVITDGKFNIL
                     KQEKVLKERIVKICVIENEIYVMGCENRIVKYRII"
     CDS             complement(16130..16618)
                     /locus_tag="ctg1_1624"
                     /transl_table=11
                     /translation="MELILEEDIKYKTPINDFGVEPINKRIITTGEKLIYFNKEKFEKE
                     SGGKVKNCEIIKYIKEKNQLFVSSMFFVSTPNGKVYKCDGNKKKIVELVFDIEDSIGVM
                     NFITSGRIVYIKNNDLFSYDVDTKELISAKLTKNRKNGNYKIFTIANCATKFRENGNI"
     CDS             complement(16665..17180)
                     /locus_tag="ctg1_1625"
                     /transl_table=11
                     /translation="VKKLIIILVLLVSGISFSNINTCKWIKNPNIYVSKEIELISRSRL
                     KGNVYCDVERDFMTYYVGIGNLEVGLVYNIRERKELRYENIFRILVDFENDIAKLIPTN
                     LPKKDTKDKPRYYTFRLYAYDARKKDTFMLFKYILDTDKVDGDWKTYYNNEIFSKTSAQ
                     THVKNFER"
     CDS             complement(17450..18412)
                     /locus_tag="ctg1_1626"
                     /transl_table=11
                     /translation="MIFLKSLGSIFPIIVMIAIGYILKKRHWFHHTFSENVSKLITNVA
                     LPCSIFYSVLKYLNMDALKEVSNRLIFTFASVIIGYTAAFFVIKLVKMREGRRGVFYNA
                     VVNANTIFIGLPLNMALFGEAASKYYLMYYITNTVSIWTLGYMLLAGDSLEGNKDEKSG
                     FNLKKLLSPPLIAFVIAFIVLLSGIKVITPIVETTKYLGSVVTPLALLYIGIVLADAGL
                     HSIRFDLDTNLALLGRFVFSSIVMIVLLKIAGHFVQLNDLEIKTFVLQSAAPVFAALPI
                     LVNETNGDIGYSTNVVTTSTILFILVVPILMSILNIIHI"
     CDS             complement(18571..20676)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gln-synt_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1627"
                     /sec_met_domain="Gln-synt_C (E-value: 4.4e-21, bitscore:
                     72.3, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENAMKSFGENVFRDSNLKKRVSKAVFKEFKASQLGETELSKETA
                     EVIANAIKDWATKRGATHFCHWFQPLNDLTAEKHDSFLEPVENEEVIYKFSGNNLIKGE
                     SDASSFPNGGLRSTFEARGYTIWDTSSYPFIRENKNGVTLYIPTAFISFTGEALDKKVP
                     LLRTMKYISEQALRVLRALGNTTANHVFNTLGVEQEYFLVKKDMFEARDDLLLTGRTLF
                     GASAPKGQELSDHYYGKIKEKVINFMSDVDVELWKLGIPSKTRHNEVAPNQFEVAPLFS
                     VANLASDQNQIIMETIEKTALRHDLVALLHEKPFAGVNGSGKHNNWSLGTDDGKNLFSP
                     GKDMKSNTQFLIFVAAVIEAVDRYYPMLRYATATATNDHRLGGHEAPPAIISVFLGDEL
                     TTVLNNIAYKKDAPVSESSKVNLSVDVLPTFSMDAGDRNRTSPFAFTGNKFEFRMPGSS
                     STPATSAAVINAMVGKVLSEYADKLEKATEKSLQKVANEIIANAYKKHHRIIFNGNGYS
                     EEWAKEAKKRGLTNEVASNTALRKMIDKDVLELTQEIGMLSEQESIARYNAYADRYVTQ
                     LSIESRTLIDIANKNILPSGLKYANLLADHIEKNAKYGKAFIKEQEEILKDVLKNITTL
                     RKEVKSLEKEINRVRNEKDLVKQTDLAKEKLVTGLEALRVPCDNLEKIIDKEYWNFPTY
                     TDLLFKL"
     CDS             20931..21599
                     /locus_tag="ctg1_1628"
                     /transl_table=11
                     /translation="MKKLLTFLLLTLSIQLFSANYKVVLKKGVTLSQQEITKNNSEIEI
                     AAKRDYDSIKRAVSVGMKSMISRMMDEQIQLPAISQKNSLKFQKKMNELYNDMFDYIMN
                     KNKIDVEKIRYVTNDIVEVTLNIKTPDFTTNLQKYSELMNSNFLNEKEMKNLDNFSEDE
                     IFDKIITKMFSSMKQSFQRTDKYASMKTTIYLEKDNGKWGIAELDEKLKNFREIYKSVN
                     "
     CDS             complement(21795..22214)
                     /locus_tag="ctg1_1629"
                     /transl_table=11
                     /translation="LVINLDETTTFFKYACNYITDAFSSGKDKKNTFVICEIKNINEII
                     KDLLEKMEFNYDDFNNTEKSTIYSDKVHKKYSFSKSKNYKSKEIIKISDGNNSIYVIDN
                     FVENDKSIILDCPLNKMLYQILYRPMPLKYSKQLN"
     CDS             complement(22304..22441)
                     /locus_tag="ctg1_1630"
                     /transl_table=11
                     /translation="MKIKYSWFDFNLIDIFGIFVGKIVYIFIDLLLQFFEKYTAINFEK
                     "
     CDS             complement(22732..23781)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1631"
                     /sec_met_domain="ADH_N (E-value: 9.9e-24, bitscore: 80.4,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.1e-24, bitscore:
                     83.0, seeds: 88, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATMKAARWHNRKDVRVEEVEVPEITRENQIKIAVKYSGICGSDL
                     HEYLGGPIFIPANAPHPYTNEKAPITMGHEFCGEVVEIGSGITKFKVGDRVTVEPILAK
                     NGLIGKYNLDPNLNFIGLAGGGGGFSEFVVVNEDQAHKLPDEIDYEQGALTEPAAVAVY
                     AVRQSRFNTGDTAAVFGCGPIGLLIIDALRASGATEIYAVEVSPERQEIAKKLGAIIVD
                     PTKVNTVEYIKEKTNGGVNVSYEVTGVPAVLQQSLEVAEKDGELMVVSIWETEAPIQPN
                     EVVIQERTIKGVIAYRDVFPKTLELMKQGYFSKDLLVTKRIKLEDIVNEGFEALVKEKS
                     QVKILVSPK"
     CDS             complement(24243..25190)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Carboxyl_trans"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1632"
                     /sec_met_domain="Carboxyl_trans (E-value: 7.9e-21,
                     bitscore: 71.2, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIKDEIKELEDNIAELKRFSAERDIDFSAQITELEKNLEDKYRD
                     FEENEMDAWNRIQISRNPQRPYTLDYIKELTQDFVELHGDRLSKDDNAIVGGLATIDGY
                     KIMIIGQQKGRDIESNIFRNFGMASPEGYRKALRLMRMAERFKLPILTLIDTAGAYPGI
                     EAEEKGQGEAIAKNLAEMFGFRVPIMSVVIGEGGSGGALGIGVADSILMFENSVYSVIS
                     PEGCASILFNDSTKAAEAAKSLRMDAISLKSLGIIDEIIKEPLGGAHRNFEETAQNLKE
                     MVVKEFKRIDKFSLRELLKRRYDKYRKIGEFFEE"
ORIGIN
        1 gttaagatag aatacaccga aacaaatata actaaaactg cttcaattat aagcatacca
       61 aatttatcca ttaacaatct ccttaaaatt caaattgcat cttttcatat tccatctctt
      121 tcattttctg tatattctgt tcaatttatc tttattccta cacaaatttg aaaaattaat
      181 attttataac aatattataa actaaaaaac aatactttac aacaagaaaa aaagccagta
      241 tttctaccag cttcctccac ctcctccgcc agaacctccg ccagagaagc ctcccccact
      301 aaagaagccg cctccgcctg agccactttt agatgaacta aatttttcac tcataatttt
      361 cgattttcca ctactgtaac ttcttgaaaa tgcattcgta aaactgtggt tactataagc
      421 gtatatatga gtatggctat ttatataaga ttcatttatg tcaaagttgt atatttttat
      481 tgtttttttc attaatttta ttgcctcgtt ttttactcca agtgctactg cgaaaggtaa
      541 aattccatta aaatattcga ttaattcctt tacattgtca aattttctta tctgattctc
      601 ttccgctgtt tttatataca ttttcatacc tttcaggtat tctttttttc ttaagccttc
      661 atttgtatat ttaccaatta actttgcata cacaataaac aatattacaa aatatgttgt
      721 aaaaacaaaa atctcaattc cctgataaaa agatacacct aaaatcacta taattaataa
      781 tcctattaac aattttttac taactgttat ccaaattcta tgaaaaaatg agcctaatgt
      841 tataagtata tacaatatta taaaagtgtt gaaaatctca aaatttgtct gtgaaaatat
      901 aaaaatcata aaaacaggag ctgtacaata aaatggaact aaaaaacttc cattattttt
      961 ataaattatt ttatgatact tatccttcag aatttcaata atactatttg ccttattata
     1021 aattcttttt tcactaccaa aaatatcatt cttttctgaa gaaagagcat caagcagcat
     1081 cctttcctct tccgccagct cagtttcctg tgtatacgca gttttggatt ccttgttata
     1141 tttaatttca ccattaactc tatttgctac tataaaccct tttgtaagta atgtaaatat
     1201 tcctgcattt aatatctcca ctgtgtctct ttcaccattt atatatgccg caaacattgg
     1261 agaaatgtct tttggcaaat taaattctgg aattacagat tttccttgcg gatcttttcc
     1321 aaaaaacttc cacgttacaa tagaatatat tgttaaaaat aacaataaaa atggcaaaat
     1381 tattattgct ggattggaaa gatatacaat ttttagctta tctactaaag ttggacttat
     1441 tttatccgtt ttcaaattta gcataaatgt aagcccattt ttggcctcca gctcttttat
     1501 tgaaatgtat atttcctcat cattttctaa aatgtcataa ttttcacctt tttctccata
     1561 acttccagta taaacttcca acttttcaat ttcatttttt ttaatttttt gcccatcagg
     1621 aaatcttata ataacacttg cctgttcaat aggaacattc caaaactgtc caatagcatt
     1681 gtaatacact tgataaattc catctttttc aaacacagca ttataaatat cgtaatttag
     1741 ctcgtatacg ctctcagtct tatacaaatt tacaagttct gtttcggaac ctattctgta
     1801 ccttattcct tcataaaaat gattttttgt atattcttca tcctttccgt ccctctttat
     1861 ccaattcatt ttgataaaag acttatgaac atcaaatcca aacctttttg aacgcaaagg
     1921 aatatctcta taaatcccgt gcttaaactc ttcgccaaac tgataatcaa tcacttcatt
     1981 tacagtcagc gtgccatttt tattaatttg cactgtaact tcataatttc ttattttttc
     2041 actatgcaat attactgcat caagcctgct tgaattaaat aaaaacatca ccataaacat
     2101 aaataatatt gaaaattttt tattttgaaa tatcatattt tatctatcct tatttttagt
     2161 tattctaaaa ctttttcagt atcaaacttt aaaaattata caaatttaaa atttatgtaa
     2221 aaatcataaa aagccagtat ttctaccagc ttcctccacc tcccccgccg gaacctccgc
     2281 cagagaagcc tccaccactt gagaatccgc ctcctccaaa accgcttccg ctcgaatttc
     2341 tagagttttc tctcaaagtg ctaaatcttt cttctgctat ttcattgtat gcattgttat
     2401 aacctcttga aatcatatct gataaaaaga aattattgta tgaattaaaa tgtactcctc
     2461 tatttatgta agaatatgta ctttcatcaa aatcataaag ttttattgta ttcttcataa
     2521 gttttactgc ttcatttttt acaccaagag ctactgcata aggcaatatc cctttaaaat
     2581 aggctaccag ttcatctaca tcattaaatt tcataatttg atttgcttca gcagtcttta
     2641 tgtacatttt cattccgtcc agatattctt tctttctcat tccatcaaca gtatatcttc
     2701 caattatttt tgaataaaca acatacattg ccataattat tccaattata atgaaattta
     2761 aaactccata tattaatgaa aagaataata ctgctatcca cttaataatt tttaaaaatt
     2821 tgctattatt tccataaata ttattgataa ttgaaaaaat cgtatttaat actattccaa
     2881 agaaaatagc aaccataact agagaaactg ctccagaaat gccatccgaa atacctgccg
     2941 ttccgctgct tgcagttgat gaaatcataa aaactataat cataccgaca ataaagacaa
     3001 tattaaaaat gttattatcc ttgtaaactt tctttttata ctctttttca aatgatttta
     3061 atattttatt tgaagcatcg taaaggcttc tttctttttt aaatatgtat ccattatcag
     3121 aaagagcatt aaaaacaatc ttttcttctt ctgctaattc aggcttgctt tttctactgt
     3181 cagacaatgt atattctaca tttcttccat taccttcttc atcattagct tcaacataac
     3241 ctttagaaag caatgaaagc actccgattg ttagtatttc ttttggctct ctttctccat
     3301 tgatataagc cgcatacatg gcagaaatat cctttggtat gttaaattca ggaacaattg
     3361 cctttttatt tacatctctt ccaaatatat accacgttac aaatccataa attgctagaa
     3421 ttattattat aatcggtcct acagcaatta aaggatgagc ataataaagt gtctgtaatt
     3481 tatcccaaaa tgttgggctt atattatctg tttttaaatt cagacgaaaa cttaatccat
     3541 tatatgcctc taaaacctta tttgttttaa tttcaacagt tccattattc aaatttgtaa
     3601 tataatcttt cccactttgt ccatattcac ctgtaaaaat atctaattgc ctaatttcat
     3661 tttttaaaac aggttctcca tttccaaatt ttatatttac cgcagctttt tcaataggaa
     3721 cttgccaaaa ttgaccaatt gcattaaagt aaacctgata aattccattt ttttcaaata
     3781 ctgcattata aatcacataa ttaaattcgt atctatttac gccattttcc acaaatctgt
     3841 ctgcagaacc aaccctatat ctaatacctt catcaaaaag ttttgtagag tattcttcag
     3901 aaataccatt tctctttatc gaattcattt ttatataaga tttgtaaata tccacgccgt
     3961 ttttctttga acgtaacgga atatccctat aaataccgtg ctttgccgca ccgtcaaatt
     4021 catagtcaat cacttcattt actgtcaaag tcccattttt attcatctga actgtaactt
     4081 cataattcgt tattttttca gcaattaatg atttcgcact taagaaaaat aatgtgaaaa
     4141 atacaaacat tattgaaaaa atactgttta attttcggtt gctaaaactc ttcataataa
     4201 tttccttcca atgcttcatt agaagctttt tccaatattt cttttgcaaa tatctcattc
     4261 ccaaatgatt tcataaattt atcattttta taaataaata tattaagtgt attttcaata
     4321 tattcctttt tatcctcaag ccctgatatt tctatagatt tttttatcat ttctacaaca
     4381 tgtttttgca ctttcaaagc ttgtgaaaat ggtaaaatct ttttaaaata tgaaatcaac
     4441 tcttctacat cattaaactt tttaacttcc ccacttttta cgtacatctt aaatccttcc
     4501 aagtcctttt ttatcctagc ccctccatct gtaaactttc caatattcct aaaataaagc
     4561 acaagtaaaa ttgttaccaa ggttataatc actcctgcta ttccaaaagg aaataacata
     4621 agtcctgccg aaaaatatac aataccacag aataccccta ttaaaagaga aatcattaat
     4681 tttatcaata ccggaaatcc tttagttttt aaaattaaaa aaagtatatt tgacaaaagt
     4741 attgcccaga aaaatgttgg aaaaagaaca attaatggca caatcgcatt cattccttca
     4801 aaaataaaaa gtaaaattcc aaataaaaat attataatta tgtaaagtat ttttaacttc
     4861 caatttgaat tataaaacct tttatcccat ttttccctat ttatagactt tattccaatt
     4921 aaatacaaga aagcgtagtt tcctctccca tcaaattttt ccttcaaaac ctcaagaatt
     4981 ttaagaagct ggttcataat agggttttta tacccaagaa tactctcctt gtcgtattca
     5041 atcaaaaatt ctaaaatcat tctctcttct tctgaaagtt cccattgcct acatccataa
     5101 tcattgattt tacccatatt gaacccatac ttcttcttgg ttatctgtct ataatatttt
     5161 ttaatgtcaa caatttcaac agtcttttta tctttcttta tttcgtgttc atcttctgtc
     5221 actttataat ttttcaaatc aacataatct tcaattatta caaattcttt gcttattagt
     5281 tccaataatc caagatatgc caaatctatt gtctgctttg aaccatccat ataagccgcc
     5341 atcattgctg aaatttcttt aggcggctct gacaccgaaa taatttcatc aacagaattc
     5401 ttcccaaatt ttttccacgt aatatagcta taaatcacca atgttattaa cattatcaat
     5461 aaaattatta tttgagtcaa acttatttcc ataaagttat ttcctttacg ataattttac
     5521 taaaattttt taaaacttaa cttctggagc cttttctgct ccttccacag cattaaagaa
     5581 ctcggctttt ttaaatccaa aaattccacc aaaaatatta ttcggaaaag tttctacaaa
     5641 agtatttctg tctcttgctg ttccgttata atattttctt gaactttgaa tttctgtttc
     5701 tatttgagtc aattgagatt gcaggctcaa aaagttttca tttgccttca agtctggata
     5761 attttcctgt aacatcatta ttgatcttaa cgtttttgtc atttcatttt caagtttttg
     5821 aattttttca atattatcaa tatcctttgt atcaatcgac atcatttgac ttctcaattt
     5881 taccacattt tccagcgttt ccttttcatg cgttgcataa cctttaacag tattaacaag
     5941 atttggtatc aaatccagcc ttttttgcaa atatacgcct attccactcc aaccttcctc
     6001 attcagattt tttagtctaa tatatttatt ataaattccc attccgacta caaccaaaac
     6061 taccaaaatt cctattaaaa taaatacaat actcataatt cattctcctc ttctattttt
     6121 tatttttatt tattttattt accataaatc caattaatat taccacaacc acccctataa
     6181 aaacattata ataaaccgtg taatctcttg gctttgaaac tttcttttca tctgcttttt
     6241 ccaattttcc tacaaaaact tcatctcgtt cttttattga atcagcaaat tccgcaatat
     6301 cgtacttagg cttatctaaa ctttcatctc caaaggttat tttataatct tccccttctg
     6361 tagccctaaa cacaattctg tctggaacat agtttcctgt tacttcattt attttgagcg
     6421 gtgaattatc tccattctgt atttcaacga ttatttcaga caattttgga acattttcta
     6481 aatttattat caaatttgac ttttccccaa ctttagaaat tatcccttct gcataaaaat
     6541 tatctccgct tctcacagta taatttctct gaaactcatc atttacatct aaaacaatat
     6601 tttttaatgg caaaaacttg ctcttgattt tcagaattgt actttttcct tcctgctcaa
     6661 ttttataatc caattttatc cctacagttt taagttttcc agcctcatta tttgacaatt
     6721 tcaaaattgc ttcactaaag atatttcctt tatctaatgg cgttacaatt ttataaaatt
     6781 catatctttt ttctgaaaat tcgattgtca agtttgactt atcaggtgtc ttataaattt
     6841 ctcccgaagt tatctgttcc caatctgtac cgttattact tccaagcaaa gtatattcgg
     6901 tgtaaaaatt tttggaagga atcagcgcaa gcctgtttcc aattatatcc tttaacaaac
     6961 tgtcagaatt aaattttaca ataaattcca ttttatcctt tttcgtcaat acttcatcta
     7021 tttttgccct tgctacaatt ttttcgctgt gtttttcctg ttcttttcca gtttcgataa
     7081 cataaggaac ttccttacca ttcttatcaa ttatccgtat atctccaaga ttatttttac
     7141 tgttctcata aatatcctct gttagaaaaa attgcttgta tgcagatttt cctgttattc
     7201 ttatagtttt aaaatactga ctggaaaaaa gttgaacaat tgtcaataaa aataaaaaca
     7261 atattatttt atttattttc ttcatttttc tcacctttcc caaaattctt gtcactcaag
     7321 ctctctttca cttcctgctc caacttcttt aaagccgtct gataaatata agaagttcca
     7381 atcaaaatag cccccatact aaaataagca atcaacttat aggaattatc aaatcgtaag
     7441 aaatcccata aaaaactttt tgccacaaaa aatattccta ttccaagccc aattcttcta
     7501 acattcctat ttggcactct aaatcctttc cagactaaat atccacataa tagcagtcca
     7561 actatatcca aagctagtcc agctcctaaa attaatacac ctgaatcttc atatatccgt
     7621 aaaataatat ttgctacaca aaggaaatat attgattctc ccagtatcca caacggcttt
     7681 ttctcatttt ttttgaaaaa gcataaatga atatcatttt tagcaaccat aaataaatat
     7741 atatttatta aaattggcaa aaagaacgga aatatataac ttattgctac tctttctatt
     7801 aatatatcca tatccgaact ccaaccaaaa aaatacagga taagattaat catatttatg
     7861 aataacaaat aaattatttc aattattatc aagaatttca aattaaaact atcttgtaat
     7921 ttttcgcttt acacgttact gttcttaaaa caaaaagcga aactaataaa ctcaaaaata
     7981 tattttcacc ataatttatc attttaaatg aagtaacaac attaaaaaca actttattta
     8041 taaaaaatat tgaatatgta aaaatcagat atttaaatat tccatttaaa atcctaactt
     8101 ccgtcttgta gcttttttgt tttatcagga aataaagcac aaatgaaaaa gatattatca
     8161 tcaaatcttg aatatacaca agcaaatatt tttcttcccg cacaattaaa ttacttacca
     8221 gcgaaactag ataaatcgca atcgttccat atcgcatttc tttgtttttg tattttctat
     8281 aaaagaaata taatagtgca gtttcagcac cccacgcaac cacaacaaat ttttctggca
     8341 caattaacgg aataatcagg ataaaacttc ctaatgcaac tatataaaag atttttgcaa
     8401 ctttgttgtc ctttagcctg tcgccaaaaa atccgtaaat tattccgact gttccaacta
     8461 atacggcttt tagccaactt ggcgttgcct tgtcaaacaa gctgtaaatc aatgaaaatt
     8521 ttataattag atttaaactt agaaatatat agtcgattat gttgctttgg cgattttctt
     8581 ttttgtgtga atttaggaaa atgaaactgt atgctgttgt gaaaattatg atgtagaaaa
     8641 atgctgtaat cttgtcgtga atactatgat tcaaataata aactagcccc gtcatattta
     8701 ctacacctgt aacaaatcca aaaatcttgc tatatatcca gtcttttttc caagaaactc
     8761 caagcacaat tccctgcaaa atcaaagaat atgccaaaac ataataaatc tggacattgc
     8821 tcttattcac ccaaatataa gctccgtaag gcaaatatcc accaatcagc gacaatactc
     8881 caattatctg gctatcatat cgcaatgaaa gaatcacaac cagccctgtc agtattaccg
     8941 atataaaaag tcccgctgtc attggataga gtttaagata aagcgtagaa agaagcgtag
     9001 tcaaataaag aataccaatt ccaccgccaa tcagcccaac tgcaaaatgc tttttatttt
     9061 tctgataaaa tttttctcca gcaaaaagaa aaaacatccc aagcaaatac gaagccgaac
     9121 tttttacata attatttgaa agaattttta caaactgtgt ccgaaatacc aaaaaaactc
     9181 ccaaaaagat tgatattatc cctaaaaagt taaatccctt caaaccaata agtttttcaa
     9241 atacaaatct ttttttctct ctttcaaaaa ggatttcccc ttccttcaaa gccgtttctt
     9301 cttttatctt attatgaaac accgaagatt cctcttgaag aaatacttta ttttcaaaag
     9361 ttttcctatt acttttctct aaaaaatcac caattttccc attaattttt ttgagttcat
     9421 ctcttaatga atcagcttca tctgaaaatt cgtgagaaag atttctttcc agcattttga
     9481 cttttctctt catttcctct gcataattag aaagtcttct agtcactcca ctttccaatt
     9541 ccacattcat cttcgcagcc aaaatattct gaaacttatc aatctcacca tttctcctaa
     9601 cctttttcgc ttccttcaat tcctcaataa gcactgcatt actattttta agccttccaa
     9661 tttcctcttc cctaattttc accttttcat gaaatgcctt taaatctttc actagccttt
     9721 cattctcttc caaaagttcc ttttccctgc ttattccagc ctcatttttt atatttgcaa
     9781 ttattaattc tatctccgaa tttattctcc caatttcctt atacttattc tcaagattct
     9841 ctaattcttt tagtttgtca atcattgtaa aaccacctca aaactcgcaa attttttata
     9901 aatgtattct gtcagttttt tgcaacatat tatccaatct actatattca aaaaagtatc
     9961 tgtaccattt atgcacaaac acttttttct ttaaaataaa ctatttataa ataaacaata
    10021 aaatttctct tagcaacttg caagctagtg ctgtagattg cccagactgg tcatacacag
    10081 gcgataattc gttcatatca agcccaacaa tatttaactg cgaaattttt tctattgcct
    10141 tatgaagttc cacaaaagtg actcctccag cttcaggtgt tccagttcca ggaaattccg
    10201 atggatcaag tacatctaag tctaatgtaa aatacacagg tttccctttt aatttttcta
    10261 caacttcatc aagtccatca aaattaaatt ttgttgtatg aagatgttcc tttgcaaatt
    10321 tccattcatc tctttcaccg cttcttattc caaactgaaa aattctgcca tctccaacaa
    10381 tgtcccaaca tcttctaatt acagaagcgt gtgaataata ctgtcctaaa tactcatctc
    10441 tcaagtctgt atgtgcgtca aactgtataa tatgcaaatc tggatatttc tcagcaaccg
    10501 ctcttacagc tcccaatgta acagaatgct ctccaccaat cataaacgga attttcccat
    10561 ccttcaaaat ttctgccgtt tcatcctgaa tatcctgcaa tgcactttct gaatttccaa
    10621 acgaaagttc caaatctcct ccatcaaaaa ccttaatatc ctccaaatcc ttatcttgat
    10681 aaggactata cgtttctatt ccaaaactct catttctcat aactgctgaa gcaaatctag
    10741 tccctggtct aaacgaagtt gtactgtcaa acggcgcccc aaaaatagca attttactct
    10801 cattgtattc attgtcgcaa cctataaatg tatgtatatt tttatttctc atataaattc
    10861 tccttatcgt atttattcta aattatttta ttaaatcttt cacataattt ggcaaagcaa
    10921 atgctccttt atgcaattcc gtgttataat atttcgtttc tatcccaaac ttattccatt
    10981 catcagcctt caaatcttct acaggattga atttttttga agcaaatcca aatagccaat
    11041 gtcctgacgg atatgtcggt atatgcagtt gataaactgt tgcaaatggg aaaaccgccc
    11101 ttaattgttt gtttgccctt gctgttgctt tagcatctgc ctcataatat gggctctcgt
    11161 gctgattcac aagaattccg tcttctttta atgcattaaa gcagtttcca taaaattctc
    11221 ttgtaaataa atcttctcca ggcccaaacg gatctgtcga atccacaatt acaatatcat
    11281 attcatttgc cttggaacgt acaaatttca atccatcctc ataataaata tgaactctct
    11341 tgtcatccag cttattcgct gtcttaggta aatattcacg acaaaggtcg acaaccatct
    11401 tgtcaatttc caccatatca attctctcaa tatgctcata ttttataagt tcacgaacag
    11461 taccgccatc tccagcaccg attaccaata ttttcttagc cttaggattt acagccatag
    11521 gaacgtgagt tatcatttca tggtaaataa actcatcctt ttctgtcagc atcataaatc
    11581 catccaatgt caaaaatcgc ccaaactctg gcgactcaaa aatatcaatt ctctgaaaat
    11641 cacttttcgc actaactaac tgcttatcaa tctttataga aaaacgaaca tttttcgtat
    11701 gttcttctgt gtaccataat tccatctgct acactccttt caatttgtat tacctatttt
    11761 tttaatatct aatcttttat ttccaatgtt ttgtacttta aaactttttt ataaattcct
    11821 caaaatttcc attgtttata attttattct atttcttaca ctcattaaac gtttctcaaa
    11881 taattttcct taaccttaac tctgttcagc catccagcta gaaaatcatt ctgagttaca
    11941 ttatttttag caagagattt gtaatattca cgctgtaaat tatgataaac catcaaaaat
    12001 ttagctggat taacttcgtt taaatatttt aatgtcatag gcccaaccgc tccatctaca
    12061 ctaattacat ttttaccata aaccttgttt acagcttcct gagccttttt aattccatat
    12121 cttccagcat ttactgaaaa atcaaatatg cttagtgcca ctttatcatt tttgacttga
    12181 tccaattttc tagccttata atatttttcc tcataaattt tttgtgccat tgcttttgtt
    12241 aaatctttca tgctaccttt gtatccacat tctctggctc gttccttagt aataccatat
    12301 tttgtttccc cgcctttatc attcttatca ttagagtagc ttccttcaac taataaaata
    12361 taattaaaaa atttcaaaaa tctgctgtca gccatttttg gtttccttct ttcatttatt
    12421 ttaattggaa tttcgcagat actgtctgcg tttttacatc aaaaattttc actccaaaac
    12481 aacatttatc ttttcaacat gcatatcctc agttcctgtt aatagacatc ctttttcctt
    12541 tgcatattca atataattta tgatttcctc agtaattcgc tctcctggtg ctaatattgg
    12601 tatccctggc ggataagcca taacaaattc accacttatt ttaccagcac tttcttttat
    12661 gggaatcatt tccttttctg aataaaaggc tttttgtggc ggaagcacaa catcaggatt
    12721 tatatattca tgatcaaaca ttcctgtaga gtcttttgag taaagccgtt taatttctgc
    12781 aagtgaagat attagccgtt ctatttccaa acctctgtct cccgccgaaa ttatcgccaa
    12841 aatatttccc aaatctccaa attcaatctg aatttcataa tcatcccgca aaatatcata
    12901 aacttcaatt ccagcaagcc caatatcctt tgtatacaca gataattttg tcgtatcaaa
    12961 gtcataaacc gaatctccat caatcagttc tttcccatag gcataatatc cacctagttt
    13021 attaatttca tttctggcat attctgcaaa tttaactgtc ttttcaaaaa gttcccttcc
    13081 atttattgct aaattttttc ttgccacatc aagcgaagtc ataagcaaat acgatgcact
    13141 cgtagtttga gtcaagttta taacttgccg aacataatca gcgtttattc tctcaccact
    13201 taacaaaatc gaactttgtg ttaaagaacc acctgtctta tgcatactaa ttgccgccat
    13261 atctgctcca gcttccatag ctgaaattgg taaattttca tcaaagtaaa aatgtgctcc
    13321 atgtgcctca tcaactaaca caaacatatc attttcatgt gccagtttta caatagattt
    13381 taaatctgaa caaattccgt aataagtggg attattcact aatattgctt ttgcatcagg
    13441 attttcctga attgcctttt tcacatcatt aatcgacatt ccaagtgata ttcccaattt
    13501 tttgttaagt ccagggttaa tataaactgg aattgctcca caaattacca ttgcattaat
    13561 ggcacttcta tgcacatttc tcggaataat aattttatct ccagctttac aagtcgccat
    13621 aatcatagcc tgcacagccc cagttgttcc acttaccata aaataagcct cttttgcccc
    13681 aaaagcctcc gccgctatat cctgagcctc tttaataacc gaagttggat ggcataagtt
    13741 atcaagcggc ttcatcgaat taacatccat ctgcatcgca tctagcccaa taaagtcccg
    13801 aaattccttg tttccacgcc ctcctttatg ccccggtaca tcaaatctca caaccctatt
    13861 agaaagatga ttttttaaag catcaaaaag aactgtctta ttctgtctat ctgtatcaat
    13921 atttttcccc atttcttcaa ctcctttcat atttttactt ttaattatta caattctaaa
    13981 tttcaaaatt tttcactaaa tatttagaca aattacattt acattttgat tagtaactat
    14041 ttttttataa tttatatgtt tttttcttaa aagcaaaggg gaacaatcgc catccccttt
    14101 tatttcgcaa tattagttat ttcaatttct tcaaattata atatctgaag attttggcga
    14161 aagcactacg cactaatccc agctcgtcta agcattttcg attcaattat aatatgtaat
    14221 ttgatgaaaa tagataccaa gcaaaatttc gttagaagaa aaatagctgt ttgagctttt
    14281 gtaatttatt ttgaagttaa atatatttat tcgtattaaa acaatttata ctcaaaagcg
    14341 agttctattt ttcttttata agaaagtttt gcgttaagcg gggttgtaag ggcatggcgt
    14401 ttgatgccct tacgttaaaa taaataatat aaaaaaataa aaaataacta ttaactagac
    14461 aaatctataa taaaatttat acaacagtta atttgaagac ttaatttaag tataaaatat
    14521 gtttaataaa tattcattcc actataaatt tcaatcattt ccttcctaag tctatccgta
    14581 atttccagcc tttttttagg tgcgatttca taaacatctt gattgaatag ataattttgt
    14641 aatctgattt cctttattag catttttgta tggaaaatgt tagactggta tacatttacg
    14701 tcaatcgcat cgtatatttt taatttttca ggctcaatat aatcttgaat agaagttata
    14761 ttatgatctg taaaaaattt ctttcctgaa atatcccttg taaatccacg tattctgtaa
    14821 tcaatcgtaa ttatatcaga atcaaagctg tctatcagat agtttaacgt atttagcggc
    14881 gaaatttccc cgcaagttgc aatatcaata tccactctaa aagtggaaat tgaattatct
    14941 ggatggtatt ctgggaaagt atgcactgtt atatggcttt tatccaaatg ggcgtggact
    15001 gtatccgtat cctgacttgc cccacctttt tttatactgt tttcatccat tccaatttcc
    15061 tcaaaaaatg gctttcctct attacaagac ttgtcgatat tttctggact tattctttct
    15121 tctgcaatca aaacgtttac agaggcccct tgtggctcgt aatcctgctt tgatatgttc
    15181 aagacttgtg ctccaatcat ttctgccaca cgaataagta tttttgtaag cctttctgaa
    15241 ttatattgct catcaatgta tgcaatatag tccttctgct ccctctctgt ttccgcatag
    15301 caaatatcat aaatattaaa acttaatgtt tttgttaaat tgttaaatcc atataactta
    15361 attttattat tttccaactc attcatcact tcctctccca tttcttcata ttacactaaa
    15421 aattccttta aaaatcaaat aaacctttaa tttgagcatt atagtaaaac tgctttaaaa
    15481 ctaaactcaa aaggttatga ctattttact caaaccctaa atttatataa tttttagtag
    15541 tttaatttta aataggtttg agtatatttt caaaacatta ctgactcagt cttaaaaatt
    15601 tatttatttt ttacatattt ttatttattt tttattttat ttttcgccaa attatatcat
    15661 ttatacacaa tttttacaat taaaattaca aaatgaattt tcaaaaaaaa tcacagctaa
    15721 attactaact gtgattataa taaaatattt caaattattc tatactttac tatcctattt
    15781 tcacacccca taacataaat ttcattctca attacacaaa tttttacaat tctttccttc
    15841 aatactttct cctgttttaa aatattgaac ttaccatctg taattaccaa ttctccattt
    15901 tctaagccaa taaaatattt tccttcaaat tcttcaatat atgttatttt tctgtcagaa
    15961 atttttatcg aattataaag ttcctgatcc aaaatattcc atatttcaat ttctccatct
    16021 tctgttcctg caaagtattg gagtccaact atttttgaat aagtgtgatt tgtttcagtt
    16081 tttacttcaa atattttttt taatttattt tcaaaaatac ttataatgtt tatatgtttc
    16141 cattttccct aaattttgtt gcacagttgg caattgtaaa tattttataa tttccatttt
    16201 ttctattttt ggtgagctta gcggaaatta attcttttgt atcgacatca tatgaaaaaa
    16261 gatcgttatt tttgatgtat acaattctac cacttgttat aaagttcatt actccaattg
    16321 aatcttctat atcaaataca agctcaacga ttttcttttt atttccgtca catttgtata
    16381 cttttccatt aggagtagaa acaaaaaaca tacttgaaac aaataactga tttttttctt
    16441 ttatatattt tatgatttca cagtttttta cctttccgcc actttccttc tcaaactttt
    16501 ctttattaaa atatataagc ttttctcctg tcgttatgat tcttttattt attggctcaa
    16561 ctccaaagtc atttatcggt gttttatatt ttatatcttc ttctaaaatt aattccattt
    16621 ttccccttaa ttagtatact atatcttctg tcggaagata cccgctatct ttcaaagttt
    16681 ttaacatgtg tttgtgcact tgtttttgaa aaaatttcgt tgttataata agttttccaa
    16741 tctccatcaa ctttatctgt atccaaaata tacttaaaca gcataaaagt atcctttttt
    16801 cttgcatcat aagcatataa tctaaaagta tagtatcttg gtttatcttt tgtatctttt
    16861 tttggaagat ttgtaggtat gagtttagca atatcgttct caaaatcaac taatattcta
    16921 aaaatgtttt catacctaag ctcttttctt tctcgtatat tataaaccag accaacttca
    16981 agattcccta ttccaacgta atatgtcata aaatcacgtt caacatcaca ataaacattt
    17041 ccttttagtc tagaacggct tattaattca atttccttag atacatatat attaggattt
    17101 tttatccatt tacaagtatt tatatttgaa aatgaaattc ctgataccaa taaaacaagt
    17161 attattatta attttttcac ttttcctcct aaaatttaca attattacat taaatatttt
    17221 ataaattatt cattataatt agttttgaaa aaatatattt taaacttata actacatatg
    17281 ttattaattt taaaatgatt tatataattt ttattttgcc ttttatttcc gttattgaat
    17341 tttttcaata aaagtttacc acattttttt attaatttca agatttacta tattttcaaa
    17401 tttttgcaaa aaaagaaaat caaattaatg attttcaaaa tttaaaattt tatatatgaa
    17461 ttatattcaa aatactcatc agaattggaa caaccaatat gaataaaatc gtacttgttg
    17521 taactacatt tgtggaatat ccaatatctc cattagtttc attaactaaa attggcaatg
    17581 ctgcaaacac tggtgctgct gactgtagca caaacgtttt tatttccaaa tcatttaact
    17641 gcacaaaatg tccagcaatt ttcaataaca caatcatgac aattgatgaa aatacaaatc
    17701 ttccaagtaa agccaagttt gtatccaaat caaaccgaat actgtgaagc cctgcatctg
    17761 ccaatactat tccaatatat agtaatgcaa gaggtgttac aacacttcca agatattttg
    17821 tagtttccac aattggagtt attactttta tgcctgataa aagtacaata aaggctatta
    17881 caaaagcaat aagtggaggc gataacaact ttttcagatt aaatccactt ttttcatctt
    17941 tattgccttc caatgaatca cctgccagaa gcatataccc taaagtccaa attgatacag
    18001 tatttgtaat ataatacatt aaataatatt tggaagccgc ttctccaaaa agtgccatat
    18061 tcaacggaag tccaataaat atcgtatttg catttactac cgcattataa aagactccac
    18121 gtcgaccttc tctcatcttc actagcttta ttacaaaaaa agctgcagta tatccgataa
    18181 taaccgaagc aaatgtaaaa atcaaacgat ttgacacttc cttcaaagca tccatattca
    18241 aatatttcaa gactgaatag aatatcgaac aaggcaaagc cacatttgta ataagttttg
    18301 acacattttc actaaatgtg tgatgaaacc agtgtctttt tttcaaaata tatccaatcg
    18361 caatcataac aataataggg aaaatacttc ccagtgattt caaaaaaatc atttttaaac
    18421 tttcctttct ttactacacc catttctttc aaaatcaaat ctaataattc cataacattt
    18481 aaagttgatt ttacaacaat tcactacaaa aatattattt taaacaaaca aagcaaggac
    18541 tcgttaaagt ccctgcactt tttatcaata ttataactta aacagtaaat cagtataagt
    18601 tgggaaattc cagtattcct tatcaataat tttttccaaa ttatcacaag gtactcttaa
    18661 cgcttccagt cctgttacta atttttcttt tgctaaatct gtctgtttta ctaaatcttt
    18721 ttcatttctt actctgttaa tttctttttc gagtgatttt acttcttttc ttaaagttgt
    18781 aatattttta agcacatctt ttaatatttc ttcctgctct tttataaatg cttttccata
    18841 tttggcattt ttttcaatat gatcagctaa taaattggca tatttcaatc cagatggcaa
    18901 gatattttta tttgcaatgt caatcaatgt tcttgactct atgcttaatt gcgttacata
    18961 tctgtctgca taggcattgt atcttgcgat agattcctgt tcagaaagca ttccaatttc
    19021 ctgagttaat tcaagaacat ctttatctat catttttcta agtgctgtat ttgaagctac
    19081 ttcatttgta agtccacgtt ttttagcttc ttttgcccat tcttcactat atccatttcc
    19141 attgaaaatt attctatggt gttttttata ggcatttgca ataatttcat ttgccacttt
    19201 ttgcagagat ttctcagttg ctttttcaag tttatctgca tattcagaca gaacttttcc
    19261 taccatagca tttattacag ccgcagaagt tgcaggtgta gagcttgacc ctggcattct
    19321 aaactcaaat ttatttccag taaatgcaaa tggcgaagtt ctatttctat ctccagcatc
    19381 catactaaat gttggtaata catcaactga caagtttact tttgatgatt ctgacacagg
    19441 tgcatctttt ttgtatgcaa tattattcaa aactgttgtc aattcatctc ccaaaaaaac
    19501 tgagataatt gcaggtggtg cttcgtgtcc accaagtcta tgatcatttg ttgcagttgc
    19561 agttgcatat cttaacattg gataatatct gtcaacagct tcaattactg cggccacaaa
    19621 gattaaaaat tgcgtatttg atttcatatc ttttccagga ctgaaaagat ttttaccatc
    19681 atcagttcct agcgaccagt tattatgttt ccctgaaccg tttactcctg caaatggctt
    19741 ttcgtgaagc aatgctacca gatcgtgtct taatgctgtt ttttcaatag tttccattat
    19801 tatctgattc tgatctgatg ccaagtttgc tactgaaaat agcggtgcta cttcaaactg
    19861 gtttggagca acttcattat gtcttgtttt tgagggaatc cctaatttcc aaagttcaac
    19921 atcaacatca ctcataaagt ttattacttt ttctttgatt tttccgtaat agtggtcact
    19981 tagttcctgt cctttaggtg cagatgctcc aaataatgtt cttcctgtaa gcaataagtc
    20041 atctcttgct tcaaacatat ctttttttac aagaaaatat tcctgttcca ctcctaaagt
    20101 gttaaatacg tgattagccg tagtatttcc caaagcccgt aaaactctta atgcttgttc
    20161 acttatatat ttcattgttc ttaataaagg tacctttttg tccaacgctt caccagtaaa
    20221 tgaaataaag gctgtaggaa tatataatgt aactccattt ttattttctc ttatgaacgg
    20281 atatgaactt gtatcccaaa ttgtgtaacc tcttgcctca aatgtgctac gaagccctcc
    20341 gtttggaaat gaagatgcat cagattcacc ttttatcaaa ttatttccag aaaatttgta
    20401 aataacctcc tcattttcaa caggttccaa aaatgaatca tgcttttctg ctgtcaagtc
    20461 atttaatggc tgaaaccagt gacagaagtg agtagctcct cttttagttg cccagtcctt
    20521 aattgcattt gcaataactt cagcagtttc tttcgacaat tcagtttcac ctagttgcga
    20581 cgccttaaac tctttaaaaa cggctttgga aactcttttt ttcaaattac tgtctctaaa
    20641 aacgttttct ccaaagcttt tcatagcgtt ttccataaaa tttaacctct tttctgtatc
    20701 aatttcttat ggaacagtgc ttttccactc tccatttttc taactatgtt ttattataca
    20761 atgtgagaaa atataagtca aacaaaaaat ttcttatttt ctttttctat ttgatagact
    20821 gtatgataaa acacactcaa aaaaaacttt atgctataaa aaatagtaaa aacttaaaaa
    20881 atatgttaaa atactaacat aaacaaaact accaaaggag tttattaccc atgaaaaaac
    20941 tactaacttt tcttttacta acactgtcaa tccagctatt ctcagccaat tataaagttg
    21001 tcctaaagaa aggggttact ttatcacagc aggaaattac aaaaaataat agtgaaattg
    21061 agattgcggc caaaagggat tatgattcaa ttaaacgagc agtatcagtt gggatgaaat
    21121 ctatgatttc cagaatgatg gatgaacaaa ttcaattacc tgcaataagt caaaaaaatt
    21181 ctcttaaatt tcagaaaaaa atgaacgaat tatataatga catgttcgat tatataatga
    21241 ataaaaacaa aattgacgtt gaaaaaataa gatatgttac aaatgatatt gtcgaagtaa
    21301 cattaaatat aaaaacccca gatttcacaa caaatttaca aaaatattca gaattaatga
    21361 acagcaactt tctaaacgaa aaagaaatga aaaatctaga taatttctca gaagacgaaa
    21421 tctttgataa aataataaca aaaatgttta gctcaatgaa acaatccttc caaagaaccg
    21481 ataagtatgc ttctatgaaa acaacaattt atttagaaaa agataatgga aaatggggaa
    21541 ttgctgaact tgatgaaaaa cttaaaaact ttagagaaat atataaatct gtaaattaat
    21601 aaaaaattat aaaaggctac ccattttcag gtagccctac attttattaa ttctaatatt
    21661 tcagggaata tatgcaataa ctccttttat tattatttta attgactgta tataaaaatt
    21721 atttaacttt aatataacct ttatccctgt attcaaaata ttcttttagt cattttgata
    21781 tacacctctc atttttaatt taattgcttg ctgtatttca acggcatagg tctatataat
    21841 atttgatata gcattttatt gagaggacag tctaaaatta tgcttttatc attttcaaca
    21901 aagttatcaa tcacatagat actattattg ccatctgaaa tttttattat ttctttactt
    21961 ttatagtttt ttgattttga aaaactatat ttcttatgaa ctttatcaga gtaaattgtg
    22021 cttttttcag tattattaaa atcatcataa ttaaattcca ttttttctaa taaatctttt
    22081 atgatttcat ttatattttt tatttcacaa ataacaaaag tatttttttt atctttacct
    22141 gatgaaaaag catcagtaat ataattacat gcatacttaa aaaaagtggt agtttcatca
    22201 agatttatta ccaaatcata ctttaaaaat ttttctaata gatatgaatt ttatgtcgtc
    22261 ataataaatt tctttttcat aaataatcca ttaatagtta tttttatttt tcaaaattta
    22321 ttgctgtgta tttttcaaaa aattgtaata ataaatctat aaaaatatat acaatcttcc
    22381 caacaaatat accaaagata tcaattaggt taaaatcaaa ccaagaatat tttattttca
    22441 tctttttcct ttcatttatt tctaattttt ttattatatt ccacaaattt atatcataat
    22501 tttatgatac agtcaatcta cttgaaaatt taagaaaaat atttaaaaat aatgaattga
    22561 ttataaatat agcctagttt cttactctca ttttaaacta aaatttcaaa aaaggataag
    22621 tgacaaatta aaaggattag tccctgattt atttagaaac taatccttat taataagtta
    22681 aattaagttt ttccgatttt aaagctagta tatacatctt atattttaca attatttagg
    22741 cgatactaaa atcttaactt ggcttttttc ttttacaagt gcttcaaatc cttcatttac
    22801 gatgtcttct aatttaattc tttttgttac taataaatct ttcgagaagt atccttgttt
    22861 cattaattcc aatgttttag ggaatacatc acggtatgca ataactcctt ttattgttct
    22921 ttcttgaatt actacttcat taggctgaat tggagcttct gtttcccaga tacttacaac
    22981 catcaattct ccatcttttt cagcaacttc taaagattgt tgcaatacag caggaactcc
    23041 tgtaacttca taagaaacat ttactccacc atttgttttt tcctttatat attcaactgt
    23101 atttactttt gtaggatcta cgattattgc tcccaatttt ttagcgattt cctgtctttc
    23161 aggtgaaact tccacagcat aaatttctgt tgctccagat gctctcaatg cgtcaattat
    23221 aagaagtcca attggtccac aaccaaatac tgctgctgta tctcctgtat taaatctact
    23281 ttgtctaact gcgtaaactg ctactgctgc aggttctgtc aatgctccct gttcataatc
    23341 aatttcatct ggtaatttat gagcctgatc ctcatttaca actacaaatt cagagaatcc
    23401 ccctcctcca ccagcaagtc cgataaagtt caagttagga tccaaattat atttcccaat
    23461 taatccattt tttgctaaaa ttggctcaac tgtaactctg tctcctactt taaattttgt
    23521 aattccgctt cctatttcca cgacttctcc acaaaattcg tgtcccattg tgattggggc
    23581 tttttcattt gtatatggat gtggagcatt tgctggaata aatattggtc ctcctaaata
    23641 ttcatgtaag tcactaccac atattcctga atattttact gctattttaa tttgattttc
    23701 tcttgtaatt tctggtactt caacttcttc tactcttaca tcttttctat tgtgccatct
    23761 tgcagctttc attgttgcca ttttgatttc ctcctatttt tcctatttta tttcttacct
    23821 taatagtata ccctactttt tcttaaaatc aatatcctct tcttattttt ctttttttta
    23881 ataaaatata gtataaatta attcgtcgga gcatttttat gcgatgacaa aactgtttga
    23941 gcatcgcgag ttttttgtca gtgcaaaaaa atgtcgtaga ctagccatag gttattgcgt
    24001 agcaatcttg ccataatttt aattattagg ataaatattt attgcaaggt aaggatttgc
    24061 ggcaatgagc aatcctacga aaataaaaaa agaaaagata taataaaaat agcaaaaaat
    24121 gtttattaaa taaaataatc taatactaaa tcctattaga aaatagtata tcattctaaa
    24181 ttgattaaat aaaaaaggat tatcaatcac ttatgataac ccaaaataat tattttaaat
    24241 ttttattctt caaaaaattc accaattttt ctatatttat catatcttct ttttagcaat
    24301 tcccttaatg aaaatttatc tatacgctta aattccttca caaccatttc ttttaaattt
    24361 tgcgctgttt cttcaaagtt tctatgtgct ccgcctaaag gctcttttat gatctcatct
    24421 attattccaa gactttttag gctgatagca tccattctta gactttttgc agcttctgca
    24481 gcctttgttg aatcattaaa aagaattgag gcacatccct ctggggaaat aacagaatat
    24541 acactatttt caaacattaa aattgagtct gctacaccaa ttcctaatgc tcctccactt
    24601 ccaccttctc caataacaac agacataatt ggtacacgga atccaaacat ttctgccaag
    24661 tttttagcaa tagcctctcc ttgccctttt tcttcggctt ctattccagg atacgctcca
    24721 gctgtatcaa ttaatgtcag aattggtaat ttaaaacgtt ctgccattct cattaatcta
    24781 agagcctttc tatacccttc aggactcgcc ataccaaaat ttctaaaaat atttgattca
    24841 atatctcttc ctttttgctg ccctattatc attattttat aaccatcaat tgttgcaagc
    24901 cctcctacaa tggcattatc atcctttgaa agcctgtcac cgtgaagttc tacaaaatcc
    24961 tgcgtcaatt cttttatata atccaaagta tatggtcttt gaggatttct tgaaatttga
    25021 attctattcc aggcatccat ttcattttcc tcaaaatctc tatatttatc ttcgaggttt
    25081 ttttcaagtt ctgttatttg agcagaaaaa tcaatgtctc tttcagctga aaatcttttt
    25141 aactcggcta tattatcttc caattcttta atttcatctt ttatactcat attctatcct
    25201 ttcgtttgaa aaattttaaa acttacacta atttttccaa tactctataa atcgttgttt
    25261 ttaagtcttt tctttctgaa attatatcaa tcattccgtg ttctagcaaa aattctgccc
    25321 tttgaaaccc ttttggcaat ttctgattta cagtctgctc gattacccta ggccctgcaa
    25381 aagcaa
//
