LOCUS       NZ_LR890181.1          21627 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LR890181.1 Citrobacter freundii strain MSB1_1H isolate MSB1_1H
            chromosome 1, complete sequence.
ACCESSION   NZ_LR890181
VERSION     NZ_LR890181.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:58:23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3378680
            Orig. end    :: 3400307
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..903)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     2.4; E-value: 0.52)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3238"
                     /sec_met_domain="LysR_substrate (E-value: 4.5e-28,
                     bitscore: 96.1, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.5e-16, bitscore: 57.5,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGKIPKTELLVTFEVVARHESYTRAAEELALTQSAVFRQVNALE
                     DFLNTALFNHAKKRIFLNAAGKHYLSIVKETLNKLERDTTTIMTWQPTVQVIELAVNPT
                     FSTHWLIPNLREFNKLNPDIIVNIHSLANIGDFLNREYDAAIMREDFYSPWSGVEYLFE
                     EEILPVCSRCLLAEPERKLAVNELLNEFPLLHQSTRIKGWQEWFALSDVSSPLVNKGPR
                     FDLLSMLIAAVRSNLGVALLPRFAIQHDLDSGDMVIPCDVPMRTGNRFIMTWREEKSES
                     EHLQIFRNWLLSKSVVSAA"
     protocluster    1..21627
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[3388439:3390938]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9760..12258
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..21627
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..21627
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="20"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1309..2097
                     /locus_tag="ctg1_3239"
                     /transl_table=11
                     /translation="VKTFGKVWLVGAGPGDISLLTLKAMMCIKQADVIIYDRLVNPKIL
                     EWALPDCLLINVGKNPGFHCVPQDEINALLVQYAQTHNNIVRLKGGDPYVFGRGAEEVE
                     DLVETGIPFEVVPGISSTIGGLTYAGIPVTHRDFASGFHVVTGHTREGNQQQDWRQLAK
                     LNGTLVIVMGIANLAFICEELLMGGKSADTPAALIMSATRDNQRRLTCTLGSLLSKAQE
                     ANILPPALIVIGDVVTLSDRLSFIPEAFKLPENLYCDSLA"
     CDS             complement(2076..2969)
                     /locus_tag="ctg1_3240"
                     /transl_table=11
                     /translation="VSLKIQDDYLQRFFSIAKVFSSATGLATVVVDVTGKILSDCHNFN
                     SFCTLMRADERYCVSCQKCDKYCAFEGLKHLKPRILSCHAGLSLFSMPLIREGHLYGFM
                     LCGQVRAKYQEYKTIIIDNEYSWMDEPKIKTEWSQVAVVDNNTLVASANLLNFIIDNFE
                     TEQQQSDEIVIPATSYMRHYFTEPSRHEKKLLAALRYIDENLYGELSLESVAAHVCLSA
                     NYFSRFFKKRQGVNFKTWVNQKKMQKAGELLHDPVHSIDSIARKLQYAQTSYFCRVFRA
                     AHQTSPQSFRHARLSQ"
     CDS             complement(3191..4060)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ligase_CoA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3241"
                     /sec_met_domain="Ligase_CoA (E-value: 6.1e-21, bitscore:
                     72.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="CoA_binding (E-value: 4.1e-32, bitscore:
                     108.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVLINKDTKVICQGFTGSQGTFHSEQAIAYGTQMVGGVTPGKGG
                     TTHLGLPVFNTVREAVEATGATATVIYVPAPFCKDSILEAIDAGIKLIITITEGIPTLD
                     MLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIMPGHIHKPGKVGIVSRSGTLTYEAVK
                     QTTDYGFGQSTCVGIGGDPIPGSNFIDILKLFQEDPQTEAIVMIGEIGGSAEEEAAAYI
                     KDHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRSLADIG
                     EALKTVIK"
     CDS             complement(4060..5226)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ligase_CoA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3242"
                     /sec_met_domain="Ligase_CoA (E-value: 3e-25, bitscore:
                     86.9, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVV
                     KCQVHAGGRGKAGGVKVVNSKEDIRAFAEHWLGKRLVTYQTDAHGQPVNQILVEAATDI
                     GKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLAGPMPYQGREL
                     AFKLGLEGKQVQQFTKIFMGLATIFLERDLALIEINPLVVTKQGDLICLDGKLGADGNA
                     LFRQADLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGG
                     EPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFGGIVRCDLIADGIIGAVAEVG
                     VNVPVVVRLEGNNAELGAKKLADSGLNIIAAKSLTDAAQQVVAAVEGK"
     CDS             complement(5317..6540)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) oxoacid_dh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63.3; E-value:
                     4.7e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3243"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.5e-18, bitscore:
                     63.3, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="oxoacid_dh (E-value: 1.8e-81, bitscore:
                     271.1, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSVDILVPDLPESVADATVATWHKKPGDAVRRDEVLVEIETDKV
                     VLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSTGKETSAKSEEKDSTPAQRQQA
                     SLAEQNNDALSPAIRRLLGEHNLEASAINGTGVGGRITREDVEKHLAKAPAAKAEAKAP
                     AAAPAPQAQLGARGEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRKQY
                     GDAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGL
                     VTPVLRDVDLLGMADIEKNIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMSTPII
                     NPPQSAILGMHAIKDRPMAVDGKVEILPMMYLALSYDHRLIDGRESVGFLVTIKELLED
                     PTRLLLDV"
     CDS             complement(6555..9356)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) E1_dh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3244"
                     /sec_met_domain="E1_dh (E-value: 2.1e-49, bitscore: 166.2,
                     seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 1.3e-67, bitscore:
                     225.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNSALKAWLDSSYLSGSNQSWIEQLYEDFLTDPDSVDANWRSTF
                     QQLPGTGVKPDQLHSKTRDYFRRQALITPRYSSSISDPDANVKQVKVLQLINAYRFRGH
                     QHANLDPLGLWQQENVADLDPSFHDLTDADFQESFNVGSFAGGKDTMKLSDLVVALKQT
                     YCGPIGAEYMHITSTEEKRWLQQRIESGRAAFSTEEKKRFLSELTAAEGLERYLGAKFP
                     GAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKRPQELFDE
                     FAGKHKEHLGTGDVKYHMGFSSDIETEGGLVHLALAFNPSHLEIVSPVVIGSVRARLDR
                     LDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNP
                     LDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRH
                     GHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEADKVATLEDATEMVNLYRDALDAGE
                     CVVKEWRPMNMHSFTWSPYLNHEWDESYPNKVEMKRLQELAKRISTVPEAVEMQSRVAK
                     IYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQAN
                     GSTYTPLQHVHNGQGTFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQ
                     VVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPST
                     PAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSTLDELANGTFLPAIGEVDELDPK
                     GVKRVVMCSGKVYYDLLEQRRKNDQKDVAIVRIEQLYPFPHKAVQEALKPFAHVHDFVW
                     CQEEPLNQGAWYCSQHHFREVIPFGSALRYAGRPASASPAVGYMSVHQKQQQDLVNDAL
                     NVD"
     CDS             complement(9760..10476)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 108.8; E-value: 4.6e-34)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3245"
                     /sec_met_domain="Fer2_3 (E-value: 3.4e-32, bitscore: 108.8,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.6e-10, bitscore: 39.5,
                     seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLEFSVYRYNPDVDDAPRMQDYTLEAEEGRDMMLLDALMQLKEK
                     DPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVVRDLV
                     VDMGQFYAQYEKIKPYLLNNGKNPPAREHLQMPEQREKLDGLYECILCACCSTSCPSFW
                     WNPDKFIGPAGLLAAYRFLIDSRDTETDSRLEGLSDAFSVFRCHSIMNCVSVCPKGLNP
                     TRAIGHIKSMLLKRSA"
     CDS             complement(10492..12258)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 391.4; E-value:
                     1.9e-119)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3246"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.4e-117,
                     bitscore: 391.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 6.6e-37,
                     bitscore: 124.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSH
                     TVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELDHMGL
                     PFSRLDNGTIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSE
                     WYALDLVKNADGAIVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDG
                     VGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAK
                     DLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHV
                     DPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEQGEDVVIPGLFAVGEIACVSVHGANR
                     LGGNSLLDLVVFGRAVGLHLQESIAEQGDLLDATEDEIDASLARLNRWNGNRNGEDPVA
                     IRKALQECMQHNFSVFREGDAMAKGLEELKAIRERLKNARLDDTSSEFNTQRVECLELD
                     NLMETAYATAVSANFRTESRGAHSRFDFPERDDENWLCHSLYLPESESMTRRQVNMEPK
                     LRPAFPPKIRTY"
     CDS             complement(12258..12605)
                     /locus_tag="ctg1_3247"
                     /transl_table=11
                     /translation="MVSNASALGRNGVHDFILVRATAIVLTLYIIFMVGFFATSGELTY
                     EVWTGFFSSAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLAVRLILQLAIVVALVVY
                     VIYGFVVVWGV"
     CDS             complement(12599..13003)
                     /locus_tag="ctg1_3248"
                     /transl_table=11
                     /translation="MWALFMIRNVKKQRPVNLDLQTIRFPITAIASILHRVSGVITFVA
                     VGILLWLLGTSLSSPEGFLTASSIMNNFFVELILWGILIALAYHAVMGIRHLLMDFGYI
                     EETLEAGTRSAKICFVIIVVLSLLAGVLVW"
     CDS             13701..14984
                     /locus_tag="ctg1_3249"
                     /transl_table=11
                     /translation="MADTKAKLTLNGDAAIELDVLKGTLGQDVIDIRSLGSKGMFTFDP
                     GFTSTASCESKITFIDGDEGVLLHRGFPIDQLATESNYLEVCYILLYGEKPTQEEYDEF
                     KTTVTRHTMIHEQITRLFHGFRRDSHPMAVMCGVTGALAAFYHDSLDVNNARHREIAAF
                     RLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEKYEVNPILERAMDR
                     ILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKMLEEISS
                     VKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKDDLLEVA
                     MELEHIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGWIAHWNEM
                     HTDGMKIARPRQLYTGYDKRDFKSDIKR"
     CDS             15205..16848
                     /locus_tag="ctg1_3250"
                     /transl_table=11
                     /translation="MGDLIYLKITGEQQGNISSGCGTSASIGNRWQENHPDEIFVFSLS
                     NGLANTDSGINTQLLNFTKLIDKSTPLLINAINNNERLFIEIDLWRINRFGRWERFYYI
                     QLRNASVKSIQTYVALNELDTEEIAVSYDYILCKHLIANTEFDYLALPAEYNRLFIPPR
                     PQPVSTIKPIVKRPSPPAPHIPAVTPVYAKSCLKEKGCTDAGSREESAENFGQMAVFAQ
                     SSVDDCCGYAQPAEASAALPILGGLTQVWGEWSLSGMLSAARGVPYIGALASALYIPSA
                     GTGSARVPGRDEFWYEEELRKKALVGGTATTRVRFFWGTDIHGKSQVYGVHTGEGTPYE
                     NVRVANMLWNDEHHRYEFTPAHDADGPLITWTPENPATGDLPTHTGSNVPPLDQPTLLV
                     TPIPDGKNEYTTPPFLVPDVADFNDYILVFPADSGIQPIYVYLSERKTSYTHRHKHYPS
                     KNRPWEEVIKNTKSGPAKFKPEVHIESVDQDVWENGTPTTNGQNWKVKEFNNVQGAYKG
                     KETKWVVTKESQGTIHSHPIGSNEARKLTK"
     CDS             16845..17186
                     /locus_tag="ctg1_3251"
                     /transl_table=11
                     /translation="MKTNYCILGNNYHIENVENIYDEISALDFNKTELEEVTRLDEDLF
                     QLALNDGVVVDIGWYPSFEEGGEFIIQVIQNSDWDHPMIKISSGWDKNELIEKLNIVLE
                     QLPFCLKVE"
     CDS             17244..17525
                     /locus_tag="ctg1_3252"
                     /transl_table=11
                     /translation="MNHLKQKLEDYTESEFLDFLNEFSANPRYQGEMDRESYIDSLVDH
                     FDKIVDHPESNGLIFYPPDDREDSPQGVIDEIKRWRKSQGRSSFKQST"
     CDS             17467..18006
                     /locus_tag="ctg1_3253"
                     /transl_table=11
                     /translation="MKSKDGVSPRDAHHLNNQPKNFQIKHSNYQCKLYNNEYLYMWEFK
                     MTITVTVQAQLIVGEKQVIESLAPEGSYTAVFEDDGQTGYFYALDESADGNPIKDALHI
                     YNAEDVSDGHIPSDVKIGWSEDSKKCVLLINGYPHGVFDFESKKGYCRSGFPPTISQEW
                     SVFGHAWNDAVDDLFR"
     CDS             18129..19175
                     /locus_tag="ctg1_3254"
                     /transl_table=11
                     /translation="MPVLQWSLLFVLSLLLSLLFLLIHLPGPLLLGSMIVGIIFSLRGI
                     SLHPPRCTFLGAQAILGCMIAQNLTGSIFTTLAAHWPMVIVILLATLISSAIIGWLLVR
                     YSNLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLLVVGAAAMVTRLVMG
                     DQAQAVSEQIIWFPPLSGNLFSTLMLAAVAGTAGRLLRIPSGVMLLPMLVGALLNASGV
                     MVIELPEWLLAIAYMAIGWQIGLGFDKQIFLMALRPLPQILLSIFSLMAICAAMAWGLA
                     HYMQIDFLTAYLATSPGGVDSVAVIAAGSHADMALIMAMQTLRLFSILLTGPAVARFIS
                     VHAPKRPA"
     CDS             complement(19172..19963)
                     /locus_tag="ctg1_3255"
                     /transl_table=11
                     /translation="MPEGPEIRRAADNLEAAVKGKPLTEVWFAFEQLKPYQSQLIGQSV
                     TQLETRGKALLTHFSNGLTLYSHNQLYGVWRVVDTGEIPQTSRVLRVSLQTHDKTILLY
                     SASDIEMLTPEQLTTHPFLQRVGPDVLDLRLTPDEVKARLLSPRFCNRQFSGLLLDQAF
                     LAGLGNYLRVEILWQVGLTGQHKASQLSDEQLDQLAHALLDIPRLSYNTRGLVDENKHH
                     GALFRFKVFHRDGEACERCGGTIEKTMLSSRPFYWCPGCQH"
     CDS             complement(19978..20622)
                     /locus_tag="ctg1_3256"
                     /transl_table=11
                     /translation="MKTVLITGFEPFGGESVNPSWEVVSGLDNAIIGGCRVVARQLPCV
                     FGESLIVLNGAIDALSPSLVLAVGQAGGRTDITVERVAINVDDARIADNQGQQPVDVPI
                     VADGPAAWFSTLPIKAMVMAMRNAGIPASVSQTAGTFVCNHVMYGLLHKLRDAPAVKGG
                     FIHIPYLPQQAAQHPGAPSMAAETVRRALEVAIATSLQVESDIAVTGGATH"
     CDS             complement(20632..21627)
                     /locus_tag="ctg1_3257"
                     /transl_table=11
                     /translation="MNFQQSYLYWLAGAVLLIVAVMSWQDKANPRRFTTGLFWGIYGVL
                     FLLGDWTFSLFGDKRAVHIAVGIAVVILALIAGFGGVKLGSYHQRTQQQREESASRLGN
                     RLFFPALAIPVVTVIGVLMFNHIPGLQDALFGPGNHATLVTLFSMTAGSLIGLAMAIKM
                     THERVHQPIQEARRLLDSIGWAFILPQILATLGLLFTAAGVGNGISYLTQEYLAVDSRF
                     IAVAVYTIGMALLTMVMGNAFAAFPIVTAGIGIPILVLQHGGNPAVMAAIGMFSGYCGT
                     LMTPMAANFNIVPAALLELPDKNAVIKAQVPTGILLLLVNVFLMYFLMFL"
ORIGIN
        1 tcaggcagcc gatactacgg acttactgag caaccagttg cggaaaatct gtaaatgctc
       61 ggattccgat ttttcttcac gccatgtcat aataaatcga tttccggtac gcatcggaac
      121 atcgcaagga atgaccatat cgccactgtc cagatcgtgc tgaatggcaa aacgcgggag
      181 cagcgcaacg cccagattag agcggaccgc cgcgatcagc atcgataaca aatcaaatct
      241 cggaccttta ttcaccagcg gactgctgac atctgacagc gcaaaccatt cctgccaacc
      301 tttgatacgc gtgctttggt gcaatagcgg gaattcgttt agtaattcgt ttaccgccag
      361 ttttcgttcc ggttcggcca gcaaacagcg actgcatacc ggcagaatct cctcttcaaa
      421 caggtactca acccctgacc atggcgaata aaagtcttcg cgcatgattg ccgcgtcata
      481 ctctcgattg agaaaatcac caatattcgc cagggaatga atgttcacga taatatcagg
      541 attaagtttg ttaaattccc gcaggtttgg gatcagccag tgcgtgctga acgtcggatt
      601 caccgccagc tcaataacct gtaccgtcgg ctgccaggtc attatcgtcg tcgtatctcg
      661 ttcaagctta tttaacgttt ctttaacgat gcttaaatag tgtttgcccg ccgcatttaa
      721 aaaaatgcgt tttttggcgt gattaaatag cgcggtattg agaaaatcct ccagtgcatt
      781 tacctggcgg aaaacagcac tttgtgttaa agccagctct tcagctgccc gggtataact
      841 ttcgtgacgc gcaaccactt caaaagttac cagcaactcc gtcttgggta tttttcctct
      901 cataacctct tccatttgca gcgtacaaaa atagtttaat ttataaaaaa taattcaaga
      961 cacccagata agcatcgaga gttatatttt attttatcca ttgatgtcat tgatccaatc
     1021 catgatttac tcacactgat gacgggtaaa tattaaccaa taatacttaa gggaaacaat
     1081 aaacacaatt taaataaggt taaacttaag caaatagtgc caataagttc ttaataattt
     1141 ttcaagtcat cttgtttatt gcagaaaaaa ctttgcgaga ttaatcaata ttatcaatgc
     1201 gataattttg gataatttca cgttataact tacgggcaaa cgactgcttt ttatcattcc
     1261 ttgatgtagt ttctgccttt ttttgttaga cgtgataaag gacacaatgt gaaaactttc
     1321 ggaaaggtct ggctcgttgg ggcaggtccc ggtgatattt cattgctcac cctcaaagca
     1381 atgatgtgca ttaaacaggc tgacgtcatt atttacgatc ggctggtcaa tcctaaaatt
     1441 ttggaatggg cattaccaga ttgcctgctt atcaatgtcg gcaaaaaccc aggcttccat
     1501 tgtgtacccc aggatgaaat caatgcgctg cttgtccagt atgcccaaac tcacaataat
     1561 attgtacgcc tgaaaggtgg cgatccgtat gtttttggac gcggggctga agaagttgag
     1621 gatctcgtcg agacaggcat cccgtttgaa gtggtgccgg gtatcagctc aaccattggt
     1681 ggcctgacct atgccgggat tccggtaaca caccgcgatt tcgcctcggg atttcacgtc
     1741 gtgaccggtc atacacggga gggcaaccaa cagcaggact ggcgtcaact ggcaaaactg
     1801 aatggtacgc tggttatcgt catgggtatc gccaatctgg cgtttatctg tgaggaatta
     1861 ttgatgggtg gaaaatcagc agatacgcct gcagcgctta ttatgtctgc cacccgcgat
     1921 aatcaacgcc gactaacctg tacgctcggt tcactactga gcaaggcgca ggaagctaac
     1981 atccttcccc ctgcactgat agtgattggt gatgtggtaa ccctgagcga tcggctctct
     2041 tttatccctg aagccttcaa gctgccagaa aacctttact gtgacagtct ggcatgacga
     2101 aaagactggg gcgacgtttg atgcgccgcc cggaaaacgc gacaaaagta gctggtttgt
     2161 gcgtattgga gtttccgggc aatgctgtct atggaatgaa cgggatcgtg caataactcc
     2221 cccgcttttt gcattttttt ctgattcacc caggttttaa agttaacgcc ctgccgtttc
     2281 ttaaaaaaac ggctgaaata gtttgcgctt aagcagacgt gagctgctac ggattccagg
     2341 gataattcac catacaaatt ctcatcgata taacgcaacg ctgccagtag ctttttctcg
     2401 tgtcgggaag gttctgtaaa ataatgacgc atgtaactgg tcgctgggat aacaatctca
     2461 tcagattgtt gttgttctgt ctcaaaatta tcaataataa aattcaataa atttgctgat
     2521 gccaccagcg tattattatc gactaccgcc acctgactcc attcagtttt tatttttggt
     2581 tcatccatcc atgagtattc attatcaata atgatggttt tatattcctg atattttgcc
     2641 cgcacctgcc cacagagcat aaaaccgtac agatgcccct cgcgaattaa tggcatagaa
     2701 aacagactta gccctgcatg acagctgagt attctgggtt taaggtgttt taatccttca
     2761 aaagcacaat acttgtcaca cttttggcaa ctcacacaat agcgttcatc cgcccgcatt
     2821 aatgtgcaga acgaattaaa attatgacaa tctgagagaa tttttccggt aacatcaacc
     2881 acgacggtgg ctaatccagt cgcactggaa aatacctttg ctattgagaa aaaacgttgt
     2941 aggtaatcat cctgaatttt caacgacacg gtatcctccg gcattaatga aattaaagcc
     3001 ggtaatatgc agaatttaat caagagaaag aatgatgttc accgcaaaaa ataatctcat
     3061 ttatgcagat gattatgagt aatttgcaag attcagataa ctaaaaaaaa aggccatcat
     3121 cagatggcca accatgtcga aacgggacca gcccttgact acgcagagag tcagggctgt
     3181 tttttattta ttacttaata acggttttca gcgcttcgcc gatatcggcc agactacgaa
     3241 cagttttcac gcctgcagct tccagcgcag cgaatttctc atccgccgta cctttcccac
     3301 ctgcgatgat cgcacccgcg tgacccatac gcttaccttt cggtgcagtc acacccgcga
     3361 tgtaacccac aaccggcttg gttacatgat ctttaatgta tgccgccgct tcttcttctg
     3421 cactaccgcc gatttcaccg atcatgacga tcgcttcggt ctgcggatct tcctggaaca
     3481 gcttcaggat gtcgatgaag ttagagcctg ggatcgggtc accaccgatg cccacacagg
     3541 tggactggcc gaaaccgtag tcggtagtct gcttaaccgc ttcataggtc agggtacctg
     3601 aacgggaaac gatacccact ttacccggct tgtgaatatg gcccggcatg atgccgattt
     3661 tgcactcgcc cggggtgatc acacctgggc agttcgggcc gatcatgcgc acgccagctt
     3721 catccagctt caccttcacg gtcagcatat ccagcgtcgg gatgccttcg gtgatggtga
     3781 taatcagttt gataccagca tcaatcgctt ccagtatgga gtctttgcag aacggtgccg
     3841 gaacgtagat aacggtggcg gtagcgccag tcgcttctac agcttcacgc acggtgttga
     3901 acaccggcag gcccaggtgc gtggtgccgc ctttacctgg cgttacgccg ccaaccatct
     3961 gagtaccgta agcaatcgct tgttcggagt ggaatgtccc ctggctaccg gtgaagccct
     4021 ggcagataac cttggtatct ttattaatta aaactgacat tatttcccct ccactgcggc
     4081 aacaacctgc tgagctgcat ccgtcagact tttcgctgca ataatattca ggccactatc
     4141 agccagtttt ttcgcgccga gttcagcgtt attaccttcc agacgtacca cgaccggaac
     4201 gtttacacct acttctgcta ccgcgccgat gataccgtcg gcgatcaggt cgcaacgtac
     4261 gataccgccg aagatgttaa ccagtacggc tttaacattg tcatcagaga ggataatttt
     4321 gaacgcttcg gttacacgct ctttggtcgc accgccacca acgtcgagga agttagccgg
     4381 ttcgccgccg tgcagcttaa cgatgtccat ggtgcccatt gccaggcccg caccgttaac
     4441 catacaaccg atgttgccat cgagcgcaac gtagttcagt tcccactgcg cagcctgcgc
     4501 ttcacgcgga tcttcctgag actggtcgcg catttcgcgc aggtcagcct ggcggaacag
     4561 cgcgttgccg tcagcgccca gtttgccgtc gaggcagatc aggtcaccct gtttggtgac
     4621 aaccagcggg ttgatttcga tcagcgccag gtcgcgctcc aggaagatag tcgccagacc
     4681 catgaagatc ttggtgaact gctgaacctg tttaccttcc agacccagtt tgaacgccag
     4741 ctcgcgaccc tggtaaggca tcgggcctgc cagcggatcg agcgccactt tgtggatcag
     4801 gtgcggggtt tcttccgcta ctttttcgat ttccacgccg ccttcggtag aggccatgaa
     4861 gaccacgcga cgggagctac ggtcaacaac tgcgccgagg taaagttctt taccaatgtc
     4921 ggtcgcggct tcaaccagaa tctgatttac cggttggcca tgagcgtctg tctggtaagt
     4981 aaccagacgt ttacccagcc agtgttcagc aaaagcgcga atgtcttctt tgctgttcac
     5041 aaccttcaca ccgcccgctt taccgcggcc gccagcgtga acctgacatt tcactaccca
     5101 cgggccagcg ccgatttttg aagcggcttc ttctgcttca cgcggagtag tacaggcata
     5161 acccaccggt gccggtaagc catagcgggc aaaaagttgt tttgcctgat attcatgtaa
     5221 gttcatgtgt tctgtccatc cttcaggtaa tcgttatctt ttacccgtag gtctgataag
     5281 catccagacc tacggggcag gtgatactct tattaactac acgtccagca gcagacgcgt
     5341 tggatcttcc agcaactctt taatggttac caggaagcct actgactcac gaccatcgat
     5401 cagacggtgg tcataagaca gcgccagata catcatcggc aggatttcaa ccttgccgtc
     5461 taccgccatc ggacgatctt tgatggcatg catacccagg atggcgctct gcggtgggtt
     5521 gatgatcggc gtggacatca gggaaccgaa cacaccaccg ttagtgatgg tgaagttacc
     5581 gcccgtcaga tcttcaaccg tcaacttgcc gtcgcgacct ttaactgcca gttctttaat
     5641 gttcttctcg atgtcagcca tacccagcag atccacatca cgcaggaccg gcgtgaccag
     5701 gccacgcggc gtggagaccg ccatgctgac atcaaagtag ttgtgataaa ccacgtcatc
     5761 gccgtcgatg gacgcgttca cttccggata gcgtttcagc gcttcaacaa ccgctttcac
     5821 gtagaaagac ataaagccca gacgaatacc gtggcgtttc tcgaacgcat caccgtattg
     5881 cttacgcagg tccatgattg gcttcatgtt gacttcgttg aaagtggtca gcatggcggt
     5941 ggagtttttc gcttccagca gacgctcggc tacgcgtttg cgcagacggg tcatcggaac
     6001 acgtttttcg ccacgcgcgc ccagttgagc ctgtggtgca ggtgctgctg ccggcgcttt
     6061 tgcttcggct ttcgcagccg gggctttcgc cagatgtttt tcaacatctt cacgcgtgat
     6121 acgaccgccg acaccggtgc cgttgatagc gctggcttcg aggttatgct cacccagcag
     6181 gcgacggatc gccgggctca gggcatcgtt gttctgctca gcaagagacg cctgctggcg
     6241 ctgtgccgga gtagaatctt tctcttcaga cttagcgctg gtttctttac cggtgctgtt
     6301 gccttcacgc aggcgaccaa ggatctggcg agaagtgacg gttgtccctt catcttccag
     6361 aaccgcatca agaataccgt ccgctgatgc cggtacttcc agtaccactt tgtcagtttc
     6421 gatttctacc agtacttcat cacgacgtac tgcatcgccc ggttttttgt gccaggttgc
     6481 aaccgttgca tccgctacgg attcaggcag gtcgggaaca agaatatcta cgctactcat
     6541 tatttatcct ttatttaatc gacgttcagc gcgtcattta ccagatcttg ttgctgcttc
     6601 tggtgaacgg acatataccc tactgccgga gaggcagagg ccgggcgacc tgcataacgc
     6661 agagctgacc caaatggaat tacttcacgg aaatgatgct ggctgcagta ccatgcgccc
     6721 tggttgagcg gctcttcctg gcaccagaca aaatcatgta catgagcaaa cggtttcagc
     6781 gcttcctgca ccgctttatg cgggaacgga tagagctgtt cgatgcgcac aatggcaaca
     6841 tctttttggt cgttcttgcg gcgttgctcc agcaggtcgt aataaacctt accagaacac
     6901 atcacgacac gcttcacgcc tttcggatca agttcatcga cttcgccaat ggctggcagg
     6961 aaggtgccat ttgccagttc gtccagcgta gacaccgcca acggatgacg cagcagcgac
     7021 ttcggtgaca tcaccaccag cggacggcgc ataccgcgca gcgcctgacg acgcagcatg
     7081 tggtagacct gtgccggggt agacgggacg caaacctgca tgttttgctc agcgcaaagt
     7141 tgcagataac gttccagacg cgcggaggag tgctccggac cctgaccttc atagccgtgc
     7201 ggcagcagca tcaccagacc gcacatacgg ccccatttct gctcgccgga agagatgaac
     7261 tggtcgataa ccacctgcgc accgttggcg aagtcgccga actgcgcttc ccagatggtc
     7321 agcgtgcgcg gttctgccgt ggcataacca tactcgaacg ccagtaccgc ttcttcagac
     7381 agcacggagt cccatacgcg gaacgtgccc tggccgttat gcacatgctg cagcggcgtg
     7441 taggttgaac cgttcgcctg attatgaatg accgcgtgac ggtggaagaa ggttccgcga
     7501 ccggagtctt cacccgacag acgaaccgga atgccttcgt ccaccagcgt ggcgtaagcc
     7561 agattctctg ccccacccca gtcgaatagc ttctcgcctg cggccatggc ctgacggtcg
     7621 ccgtaaattt tggcaacacg cgactgcatt tcaacggctt caggcacggt gctgatacgt
     7681 tttgccagct cctgcagacg cttcatctca accttgttcg ggtagctttc gtcccactcg
     7741 tggttgaggt acggcgacca ggtgaaggag tgcatgttca ttggacgcca ctctttcacc
     7801 acgcattcac cagcatccag cgcatcacgg tacagattga ccatttcggt cgcatcttcc
     7861 agcgtggcga ctttgtccgc ttccagcttg tcagcgtaga ttttacgcgg ggtcggatgc
     7921 tttttgattt tctgatacat cagcggctgg gttgcgctcg gctcgtcggc ttcgttgtgg
     7981 ccgtgacggc ggtagcacac cagatcgatg aacacatcgc gtttgaaggt gttacggaaa
     8041 tccagagcca gacgcgtcac gaaagcgacc gcttccgggt catccgcgtt aacgtggaag
     8101 attggcgcct gaaccatctt accgatgtcg gtgcagtacg gagtagaacg cgcatccaac
     8161 gggttagagg tagtaaagcc cacctggttg ttgatgacga tgcgaacggt accgcccact
     8221 tcgtaaccac gcgctttcga catgttcagg gtttcctgaa ccacgccctg cccggttacc
     8281 gccgcatcgc cgtggatggt gattggcagt actttgttgc tgctcggctc gtccagacga
     8341 tccagacgtg cacgtacgga gccgataacc accgggctaa cgatttccag gtgcgacggg
     8401 ttaaacgcca gcgccaggtg taccagaccg ccttcggttt cgatatcaga cgagaagccc
     8461 atgtggtact tcacgtcacc ggtgccgagg tgttctttat gtttgcccgc aaattcgtcg
     8521 aacagttcct gcgggcgttt acccagtacg ttaaccagaa cgttcagacg accacggtgc
     8581 gccatgccca gtaccacttc acgggtaccg ctgttacccg cgtggcggat catctctttg
     8641 agcattggga ttaacgcatc accgccttcc agcgagaagc gtttcgcgcc cgggaactta
     8701 gcgcccaggt agcgttccag tccttctgct gcggtcagtt cgctcaggaa gcgtttcttc
     8761 tcttcggtac tgaatgcggc acggccagac tcgatacgct gttgaagcca gcgtttttct
     8821 tcggtgctgg tgatgtgcat atactcggcg ccaattgggc cgcagtaggt ttgtttcagc
     8881 gcaacaacca ggtcgctcag cttcatggtg tctttgccgc cggcaaaaga acctacgtta
     8941 aagctttcct ggaaatccgc atcggtcaga tcgtggaaag acgggtccag atcggccaca
     9001 ttttcttgct gccacagtcc cagcggatca agattcgcat gctgatgacc gcggaaacgg
     9061 taggcgttaa tgagctgcag gactttaacc tgcttcacat tggcatcagg gtcggagata
     9121 gaagaagagt aacgtggagt aatcaacgcc tgccgacgga aataatcacg tgtttttgag
     9181 tggagttgat ccggtttgac tccggtacca ggtaactgct ggaacgtcga acgccagtta
     9241 gcatctaccg agtcagggtc ggttaagaag tcttcataga gctgttctat ccagctctgg
     9301 ttagaaccag agaggtaaga agagtccaac caggctttca aagcgctgtt ctgcatcgtg
     9361 atcccttaag catcttttct gcttatttaa tactctaaat agatcgcgtt tcaggaaggt
     9421 ggcaagcttg cgaatcccag ggagcttaca tccagtaagt gaccagggtg agcaagtgca
     9481 gccaacgcac atgcaacgtg aactatgacg agtatttcgc cgtggatact accacgcaca
     9541 ccgatgtgcg tgccggggtt cacttgttgc ggactgtcgt gtcatctgcg tccgctaagg
     9601 aacctttaaa aactgtctaa taatcttcgc tgttcaggct acgactgcgt tgcggccttg
     9661 tctcgctctg aacatctcga ttattactac tcatatggca gtttttagag gtttcctgta
     9721 ctaccgggga atcacttccc cggcaaccac tacaaaatct tacgcactac gtttgagcag
     9781 catcgactta atatggccga tggcgcgcgt cgggttcagt cctttaggac atacgctgac
     9841 gcagttcatg atgctatgac agcggaatac gctgaaagcg tcacttaaac cttccaggcg
     9901 gctgtcggtc tcggtatcgc ggctatcaat taagaagcga tacgcggcca gcaggcctgc
     9961 cgggccaata aacttgtccg gattccacca gaatgatggg caggacgttg agcagcatgc
    10021 acacaaaata cattcataca gcccatcgag cttctcacgc tgctcaggca tttgtaaatg
    10081 ctcacgagcc ggcggatttt tcccattatt caacaagtaa ggcttaatct tctcatactg
    10141 tgcgtagaat tgccccatgt ctaccaccaa atcgcgcaca accggtaaac ccggcagcgg
    10201 gcgaatgaca attttcttgc ccggctgatt cagcgcagaa ataggtgtga tacaggccag
    10261 tccatttttg ccgttcatat tcagaccgtc ggagccgcag accccttcac ggcaggagcg
    10321 gcggaacgac agagacggat ctttttcttt cagctgcatc aatgcatcca gcagcatcat
    10381 gtcgcgtcct tcttccgcct ccagggtgta atcctgcata cgcggagcgt cgtcaacatc
    10441 cgggttatag cgataaactg aaaactcgag tttcattgtc ctgtctccgc attaataagt
    10501 acgaatcttc ggcgggaatg ccgggcgcag cttcggttcc atattgactt gacgtcgcgt
    10561 catggattcc gactctggca ggtacaggga atggcacagc cagttttcat catcacgttc
    10621 cgggaagtcg aagcggctat gcgcgccacg gctttcggta cggaagtttg cagatactgc
    10681 agtggcgtac gcggtctcca tcaggttatc caactccaga cactcaacgc gctgggtgtt
    10741 gaactcgctg gaggtatcgt ccagacgggc atttttcagg cgttcgcgaa tcgctttcag
    10801 ctcttccaga cctttcgcca tcgcatcgcc ttcgcggaat accgagaagt tatgctgcat
    10861 acattcttgc agcgctttgc gaatcgccac cgggtcttca ccgttacggt taccgttcca
    10921 gcggttcagt cgtgccagag aagcatcgat ttcatcttcg gtcgcatcca gcaggtcacc
    10981 ctgctcagcg atagattcct gcagatgcag acccaccgca cgaccaaata ccaccaggtc
    11041 cagcagcgag ttgccgccca gacggttggc gccgtgaacc gatacgcagg cgatttcacc
    11101 aacggcaaac agcccaggga tcaccacatc ttcgccctgc tcattcacgg tcagcgcctg
    11161 gccagttact ttggtcggaa taccgcccat catatagtgg caggttggga taaccggaat
    11221 cggctcttta accgggtcaa cgtgagcaaa ggtacgggac agttcgagaa tgcccggcag
    11281 acgggattcc agtacttctt tacccaggtg gtcgagtttc agcttagcgt gcggacccca
    11341 cgggccgtca cagccgcgac cttcacggat ttcgatcatg atggaacgcg ccaccacgtc
    11401 acgacccgcc aggtctttcg cattcggggc ataacgctcc atgaagcgct cgccgtgttt
    11461 gttcaacaga taaccacctt caccacggca gccttctgtg accagaacgc ccgcaccggc
    11521 gataccggtt gggtggaact gccacatttc catatcctgc accggcacgc cagcgcggat
    11581 agccatacca acaccgtcac cagtattgat gtgggcattg gtggtggact gataaatacg
    11641 gccagcaccg ccggtcgcca gcacggtcgc acgggctttg aagtaaacta cctcaccggt
    11701 ttcaatacac agcgcggtac aaccgacaat cgcaccatcg gcatttttta ccagatccag
    11761 cgcataccat tctgagaaga tggtggtatg gtttttcagg ttctgctgat acagcgtgtg
    11821 caacagcgca tgaccggtac ggtctgccgc tgccgcagta cgtgccgcct gctcgccgcc
    11881 gaagttcttc gactggccgc caaacggacg ttgataaatt gtgccattgt cgaggcgaga
    11941 gaacggcagc cccatgtggt ccagttccag aatcgcttcc ggaccggttt tacacatata
    12001 ttcaatagcg tcctggtcac caatgtagtc cgacccttta acggtgtcgt acatgtgcca
    12061 ttcccagtta tcttcatggg tattaccgag cgcaacggtg atgccaccct gcgcggatac
    12121 ggtatgggaa cgggttggga acactttaga gagcagcgca caagtctgcc cgctctggga
    12181 aatttgcagc gccgcgcgca tacctgcgcc gccggcacca atcacaacag catcaaattc
    12241 tctgactggc agtttcatta cacaccccac accacaacaa atccataaat gacgtaaacc
    12301 accagcgcaa caacgatagc cagttgcaga atcaggcgca cagccagagg tttaacgtag
    12361 tcggtcaaca cctgccacat gccgatccag gcatgaatca agatggagaa aagtgccagc
    12421 agggtgaaga ctttggtgaa tgccgatgag aagaaaccgg tccagacttc atacgtcagc
    12481 tcgccgctgg tggcgaagaa accgaccata aagatgatgt ataacgtcag aacgatagcg
    12541 gtagcacgga ccagaatgaa gtcatgtacg ccgttgcgtc ctaatgcgga ggcgttgctt
    12601 accatacgag gactcctgcg agaagtgaaa gcacgacaat aataacgaaa caaattttgg
    12661 cggagcgtgt ccctgcttcg agggtttctt cgatatagcc aaaatccatc aacagatggc
    12721 gaatgcccat tacggcgtga tatgccagcg caatcaggat cccccacaga attaactcca
    12781 caaagaagtt attcataatg gatgacgcgg tgaggaaacc ttcaggggag gaaaggctgg
    12841 tacccaataa ccacaacaga atcccgaccg ccacgaaggt gatcactccg gatacgcgat
    12901 ggagaatgga cgctatcgcc gtgattggga accggatcgt ttgcagatcc agattgacag
    12961 gtctttgttt tttcacattt cttatcatga ataacgccca catgctgttc ttattattcc
    13021 ctttagactt cgggtacaga agatgaagac acctgtagcc tgaaagacga cgggatttcc
    13081 ttcctccggt ctgcgtgcgg gtcagacagc gtccttacta taactacgcg tcatataaaa
    13141 cactgcttcc agatgctaaa acgacacgtt acaacgctgg ttggctcggg attgcagggt
    13201 attccggaga cctggcggca gtataggacg ttcacaaaat cattacaatt aacctacata
    13261 tagtttgtcg ggttttatcc cgaacagtga cataggtcac gataacaaca ttattttaat
    13321 ttttaatcat ctgatttgac aatcattaaa caaagttgtt acaaacgaca ccagaaaaag
    13381 catataatgc gtaaaagtta tggggtcact ctttcaccgg agatttagtt atgtaacagt
    13441 gtggaagtat tgaccaatac cttcaggaca gttattagtg atagacaggt taaataattc
    13501 ggattgctaa gttcttgatt tgcagtttat tcgccataaa aagaccgttt tacctgcaag
    13561 cgcccatagc tctgtaccca ggtcatcccc tctttcgcag agcggcgagc caaataacaa
    13621 actggtaacg gtttattgat gcacgaaggc aaatttgagt tccggcagtc ttaagcaata
    13681 aggcgctaag gagaccgtaa atggctgata ctaaagcaaa actcactcta aatggtgacg
    13741 ctgctattga actggatgtg ctgaaaggta cgctcggtca ggacgttatt gatattcgta
    13801 gtcttggctc aaaagggatg tttacttttg acccaggttt tacctctacc gcatcctgcg
    13861 aatccaaaat tactttcatc gacggtgacg aaggtgtttt gctgcatcgc ggcttcccga
    13921 ttgaccagtt ggcgaccgag tccaactatc tggaagtgtg ttatatcctg ctgtacggcg
    13981 aaaaaccgac gcaggaagag tacgacgagt tcaaaaccac agtcactcgc cataccatga
    14041 tccacgagca gatcacgcgt ctgttccacg gtttccgccg cgactctcac ccgatggccg
    14101 ttatgtgcgg tgtcaccgga gcgctggcag cgttttatca tgactcgctg gatgtaaaca
    14161 acgcacgtca ccgtgaaatc gccgctttcc gtctgctgtc caaaatgcca accatggcag
    14221 cgatgtgcta caaatattcc atcgggcagc cgttcgtgta cccgcgtaac gatctctcct
    14281 acgccggtaa cttcctgaac atgatgttct caacgccgtg cgaaaaatac gaagtgaatc
    14341 cgattctgga acgcgccatg gaccgtatct taatcctgca cgctgaccac gaacagaacg
    14401 cctcaacctc taccgtacgt accgcgggct cttctggcgc taacccgttt gcctgcatcg
    14461 cggctggtat cgcttccctg tggggaccgg cacacggcgg cgcaaacgaa gctgcgctga
    14521 aaatgctgga agaaatcagc tctgttaaac acattccgga atttgttcgc cgcgcgaaag
    14581 acaagaatga ttccttccgc ctgatgggct ttggtcaccg tgtttataaa aactatgacc
    14641 cgcgcgctac cgtcatgcgt gaaacctgcc acgaagtgct gaaagaactg ggcaccaaag
    14701 atgatctgct ggaagtggcg atggaacttg agcacattgc gctcaacgac ccatacttca
    14761 tcgagaagaa actctacccg aacgtagact tctactccgg cataatcctg aaagcgatgg
    14821 gtattccgtc ctccatgttc accgttatct tcgccatggc gcgtaccgtt ggctggattg
    14881 cacactggaa cgaaatgcac accgacggca tgaaaatcgc ccgtccgcgt cagctgtaca
    14941 ccggctacga caagcgcgat tttaaatctg atattaagcg ttaattgttc aggccaccgg
    15001 gtaattccgg tggcttttct cagaccctgc tcaaattacc gcattcatct cattaatatt
    15061 attctcatca gccaattcgt cccataatac atttcagaca tgcaccccct tttatatagc
    15121 atcaatcgcc aacgcataat ttgattttta aatttattag ctatttaatt cggccttata
    15181 aaatacatct ctggattaaa tggcatgggc gatcttattt acctgaagat aacaggtgaa
    15241 caacaaggaa atatttcttc cggctgcggc acttccgcgt caatagggaa tcgctggcag
    15301 gaaaaccatc ctgatgagat ttttgttttt tcactttcga atggattagc taatactgat
    15361 tctggtatta atacccagct actgaacttc acaaaactaa ttgataaaag cacaccatta
    15421 ttgattaacg ccatcaataa caatgaacgt ctgtttattg aaattgattt atggagaata
    15481 aacagatttg gtagatggga acgcttctat tatattcaat taagaaatgc atcggtaaaa
    15541 agcatacaaa cctatgtggc cctaaacgag ctggataccg aagaaattgc agtatcgtat
    15601 gactatattc tttgcaaaca cctgattgcc aacactgagt ttgactacct ggcattgcct
    15661 gctgagtaca accgtttgtt tataccaccc cgccctcagc cggtcagtac gataaaaccc
    15721 atagtgaaac gcccttctcc ccctgcacca cacattccag cagttacgcc ggtctatgcc
    15781 aaatcctgtc tgaaagaaaa aggctgtaca gacgcgggga gccgtgaaga atcggctgaa
    15841 aacttcggac agatggcggt tttcgcacaa tcttccgtcg atgattgttg cggatatgca
    15901 cagcccgcag aagcctcggc cgcgctgccg atcttaggtg ggctgacgca ggtgtggggc
    15961 gagtggtcac tcagtggcat gctcagcgcc gcacgcggcg ttccttatat cggagcgcta
    16021 gcttccgcgc tgtatattcc gtccgcgggt acgggcagcg cacgcgttcc cggacgtgat
    16081 gagttctggt atgaggaaga actgcggaaa aaggcgctgg taggtggcac tgccaccacc
    16141 cgggttcgtt ttttctgggg aaccgacatt cacggtaaat cgcaagtcta cggcgtgcat
    16201 accggcgaag gtactcctta tgaaaacgtg cgcgtcgcga atatgctgtg gaacgatgaa
    16261 catcatcgct atgaatttac gcctgcccac gacgcagacg ggccgttaat cacatggacg
    16321 ccggaaaatc ctgcgaccgg cgatttaccc actcatacgg gtagcaatgt tccaccgctg
    16381 gatcagccaa cccttctggt gacaccaatc ccggatggca aaaacgaata caccacgccg
    16441 ccgttccttg tgcccgatgt cgccgatttt aacgattata ttctggtctt tccggccgat
    16501 tcaggcattc agccgatata tgtttacctc agcgagagaa aaacatctta tactcataga
    16561 cataagcact atccttccaa aaatagaccc tgggaggaag tgataaaaaa tacgaagtct
    16621 ggtccagcaa aattcaaacc agaagtccat atcgaatctg tagaccagga tgtatgggag
    16681 aatggtactc caacaactaa tggacaaaac tggaaagtta aagaattcaa taatgtccaa
    16741 ggcgcttaca aaggaaagga aacgaaatgg gtggttacca aagaatctca aggaactatt
    16801 cactctcatc caataggttc aaatgaggcc aggaaattaa caaaatgaaa acaaattact
    16861 gcattttagg aaataactat catatcgaaa atgtagagaa tatttacgac gaaatatcag
    16921 ctttagattt caacaaaact gagttggaag aggtaacacg attagatgaa gatttatttc
    16981 agctagcctt aaatgatgga gttgttgtag acattggttg gtatccttca tttgaagaag
    17041 gtggtgaatt tatcattcaa gtgatacaaa atagtgactg ggatcaccct atgataaaaa
    17101 tatcctctgg atgggataaa aatgagttaa ttgaaaagtt aaacatagtt ttagaacagt
    17161 tacctttttg tcttaaagtt gaataagcat tcagaaaaca aataataaca ctctgcaaag
    17221 catcttatta taaaggtgaa tatatgaatc atcttaagca aaaactcgaa gactacaccg
    17281 aatccgaatt cttagacttc ctaaatgaat tctctgcaaa ccctcgctac cagggagaaa
    17341 tggatcgtga atcttacatc gactcattag tcgatcattt cgataaaatc gtggaccatc
    17401 cggaaagtaa tggattgatt ttttatcccc cggatgacag ggaagacagc ccacaaggcg
    17461 tcattgatga aatcaaaaga tggcgtaagt cccagggacg ctcatcattt aaacaatcaa
    17521 cctaaaaatt ttcaaatcaa acactcgaat tatcagtgta aattatataa caacgaatat
    17581 ttatacatgt gggaatttaa aatgacgatc acggttacgg ttcaagctca actcattgtc
    17641 ggtgaaaagc aggtaataga aagtttggcc ccagaaggtt cttacacggc tgtatttgaa
    17701 gatgatggtc aaaccgggta cttctatgca cttgatgaat ctgctgacgg aaatcctatc
    17761 aaagatgcac tgcatattta caatgcagaa gatgtgtcag atgggcatat cccatcagat
    17821 gtgaagatcg gttggtcaga agacagtaag aaatgtgtgt tgctaataaa tggttaccca
    17881 cacggtgtct ttgattttga atctaaaaaa ggatactgcc ggagcggttt tccacctaca
    17941 atcagtcagg aatggtctgt ctttgggcat gcatggaatg atgctgtcga tgatttattc
    18001 agataacagg catcaatacc cgatcaccgg ttagtccgtt tttattgata cttgatattt
    18061 ttttcagcgg actttttctc tatgctgtat caacacgtta aacgcagcat ataactcagg
    18121 agcatgggat gcctgttttg cagtggagcc tgttgtttgt gctatcgctc ctgctttccc
    18181 tgctctttct gcttattcat cttccaggac ccttgctgct cggttcgatg atcgtcggca
    18241 tcatcttcag tctgcgcggc atctctctgc atcctccccg ctgcacattt cttggcgcgc
    18301 aggcgattct cggctgcatg attgcccaaa atctgaccgg ttcaatcttc acaacccttg
    18361 cagcccactg gccgatggtg attgttatcc tgctggcaac ccttatcagc agcgcgataa
    18421 tcggctggct gctggttcgc tacagtaatc taccgggtaa caccggcgca tggggctcgt
    18481 caccaggcgg cgcagcggca atggtggcga tggcgcagga ttatggtgcc gacatccgac
    18541 tggtggcgtt tatgcagtat ctgcgtgtac tgttggtggt cggcgcggcg gcgatggtca
    18601 cccgtctggt gatgggcgac caggcgcagg cggtcagtga acaaatcatc tggtttccgc
    18661 ctctaagcgg caatcttttc agcactctga tgctggccgc cgttgccggc acggctggac
    18721 gcttactgcg tattccctct ggcgtcatgc tattgccgat gctggtgggt gccttgctga
    18781 atgcaagcgg agtgatggtg attgaactgc cggaatggct actggcgata gcctatatgg
    18841 ccatcggctg gcaaatcggc ctgggctttg acaagcagat atttttaatg gcgctgcgcc
    18901 ctttgccgca gatcctgttg tccatttttt cactgatggc gatctgcgcc gctatggcct
    18961 ggggactggc gcattacatg cagattgatt ttctcactgc ctatctggcg accagtccag
    19021 gtggcgtgga ttctgtcgcg gtgattgccg caggaagcca cgctgatatg gcgctcatca
    19081 tggcgatgca aaccctgcga ctgttcagca ttttgttaac tggccccgca gtcgcgcggt
    19141 ttatttcggt gcacgcgcca aaacggcccg cttagtgctg acatcccgga caccagtaaa
    19201 aaggtcgcga ggagagcatc gttttctcga tagtcccacc acaacgctca caggcttcgc
    19261 cgtcccgatg aaagaccttg aagcgaaaca acgcaccgtg atgtttattc tcatcgacca
    19321 gcccgcgggt attataagac aggcgcggaa tatcaagcag cgcatgtgcc agttgatcca
    19381 gttgctcatc actaagctgc gacgctttat gctgcccggt caaccctact tgccagagga
    19441 tctctacccg caggtagtta cctaatcccg ccagaaacgc ctggtccagt agcagaccag
    19501 aaaactggcg attgcaaaaa cgcggagata acagacgcgc tttaacctca tcgggcgtta
    19561 aacgtaaatc cagtacatcc ggcccaaccc gttgcaggaa cgggtgggtg gttagctgtt
    19621 ctggcgtcag catttcgata tcagacgcgc tatacagcag aattgtcttg tcatgtgttt
    19681 gcagactgac gcgcagtacc cgcgaagttt gcggaatttc gccggtatcc accactcgcc
    19741 acacaccata gagctgattg tgactgtaca gcgtcaggcc attagaaaaa tgggtcagta
    19801 atgctttccc tcgcgtttca agctgggtaa cactctgccc aattagttga gattgatacg
    19861 gttttaactg ctcaaaggca aaccagactt ccgtcagggg tttgcctttg actgccgcct
    19921 ccaggttatc cgccgcgcgg cggatctccg ggccttcagg cataatactg tcctttgtta
    19981 atgtgttgcg ccgcccgtca ctgcgatatc gctttccacc tgcaaggagg tggcaattgc
    20041 gacttccagc gcccggcgta ctgtttcagc cgccatactt ggcgccccgg gatgctgtgc
    20101 ggcctgttgc ggcaaataag ggatgtgaat aaagccgccc ttcaccgccg gtgcgtcgcg
    20161 tagtttatgc agcaggccat acatcacgtg gttacacacg aaagtaccag cggtctggga
    20221 aaccgaggcc ggaattcccg cgttgcgcat cgccataacc atcgctttga tcggcaacgt
    20281 gctaaaccat gccgctggac catcggctac aatcggcaca tctaccggct gttgcccctg
    20341 attatccgca atacgcgcat cgtcaacgtt aatcgccacg cgttccacgg tgatatccgt
    20401 gcggccacct gcctgcccca ccgccaggac cagcgatggc gacagcgcgt caattgcgcc
    20461 attgagtacg ataagagact cgccaaagac gcacggcagt tggcgggcaa cgacgcggca
    20521 tccaccgatg atagcattat cgagtcccga gaccacttcc caggaagggt taactgactc
    20581 gccgccaaag ggttcaaatc ccgtgatgag tactgttttc atcctgtcac cttacaagaa
    20641 catcagaaaa tacatcagga acacgttgac caatagcagc agtatgccgg ttggcacctg
    20701 cgccttaatc accgcgtttt tgtccggtag ttccagcagc gcagcaggga caatgttaaa
    20761 gttcgccgcc atcggcgtca tcagtgtccc gcaataaccg gagaacatac caatcgccgc
    20821 cattaccgcc ggattaccgc cgtgttgcag aacaagaatc ggaataccaa tcccagcggt
    20881 cacgatcgga aaagcagcaa acgcattgcc catcaccata gtcagcaatg ccatgccgat
    20941 ggtgtacacc gccactgcga taaagcgact gtctaccgcc agatattcct gcgtcagata
    21001 tgaaatgccg ttgcctacgc ccgctgccgt aaacaacagc ccgagcgtgg ccagaatctg
    21061 tggcaggatg aacgcccagc cgatggagtc cagcagacgg cgcgcctcct ggatcggttg
    21121 atgcacccgc tcatgggtca tttttattgc catcgccagg ccaatcaacg aacctgcggt
    21181 catggaaaaa agcgtcacca gcgtggcgtg attacccggc ccaaacagcg catcctgtaa
    21241 gcccggaata tggttgaaca tcagcacgcc aataaccgtt accaccggga tcgccagcgc
    21301 cggaaaaaaa aggcggttgc ccaggcgact ggcactttct tcgcgctgtt gctgggtccg
    21361 ttgatggtaa cttcccagct tcacgccgcc aaaaccggcg atcagcgcca ggatgaccac
    21421 cgcaataccg acggcaatat gcaccgcgcg cttgtcgcca aacagcgaga atgtccagtc
    21481 gccaagcaga aacagtacgc cgtatatgcc ccaaaacagg ccagtggtga aacgacgcgg
    21541 gttcgcttta tcctgccagg acatgacagc cacaatcagt aataccgcgc ccgccagcca
    21601 gtagagatag ctttgttgaa aattcat
//
