LOCUS       NZ_KB903374.1          16113 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KB903374.1 Butyricimonas synergistica DSM 23225
            A3CYDRAFT_scaffold_9.10, whole genome shotgun sequence.
ACCESSION   NZ_KB903374
VERSION     NZ_KB903374.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:55:30
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 126416
            Orig. end    :: 142529
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16113
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[136416:140530]"
                     /cutoff="10000"
                     /detection_rule="(DAO and Fer2_BFD and FAD_binding_2 and
                     Fer4_8)"
                     /neighbourhood="10000"
                     /product="Respiratory_glycerol"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14114
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(DAO and Fer2_BFD and FAD_binding_2 and
                     Fer4_8)"
                     /neighbourhood="10000"
                     /product="Respiratory_glycerol"
                     /protocluster_number="1"
     cand_cluster    1..16113
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(DAO and Fer2_BFD and FAD_binding_2 and
                     Fer4_8)"
                     /kind="single"
                     /product="Respiratory_glycerol"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16113
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Respiratory_glycerol"
                     /region_number="1"
                     /rules="(DAO and Fer2_BFD and FAD_binding_2 and Fer4_8)"
                     /tool="gutsmash"
     CDS             2403..4730
                     /locus_tag="ctg16_104"
                     /transl_table=11
                     /translation="MKSLINRIYILVAAALLLLSASCSQTKKLAEGEVLYTGVKKMKIE
                     TAEGVKLEGAQSSAISSPLSYPPNNPLYAPYVRSPFPVGLWVYNWNIKKEKGLKYWLYK
                     KLAKKPVLISDVQPELRLKVVDNAAKDYGYFGVEASYEIIPNKRNPKKAKISYHVNIPK
                     PYMFGDIAFWGWKGRMDSLLQRTKQRCLLIKGTEYSVYAMEDERARITQLLRNNGYYYF
                     QSDYIEFLADTTREKRVADIRVALKHGVPAIALQPYKIGKVELVLEEPDQSGTPDSLSY
                     KEINVKYMKPLGVKPKVLARSMHLLPGNTYSFRRQNRTQTSLARLGIFKYTNVDVTRTD
                     TAKTEEFGKLNFGINAVYDLPIETEIELDVSSKSNNLLGPGLIFSITNKNLFRGGENLS
                     FKLNGAYEWEVGDKQGNSKSGLINSYELGVNVALSLPRLLVPNFLKSTKDFTERTHFQV
                     GVDFLNRHTFFRMISFTGATSYDFQSSYRVYHSVTPLKISYTHLLRTSSEFDETMENNP
                     AIAMSFKNQFIPSMSYTYTYDRGATSRNPNRFYWQNMLMSAGNILSAIQYLSGNHKGEG
                     KTIFGNTYSQFLKVTSEVIVYRKLTENSLIATRFMGGIGYAYGNSEVMPYSEQFYIGGA
                     NSIRAFTIRSIGPGSYHQKSDNKTAYLDQTGDIKLEGNIELRFKIAGDLNGAVFLDAGN
                     VWLLRNDSKRPGGEFKLSGLLKEIALGTGFGLRYDIGFIVIRGDLGVPLHTPYKNPDKH
                     GYYNIPKFWNGLAFHLAIGYPF"
     CDS             complement(5166..6134)
                     /locus_tag="ctg16_105"
                     /transl_table=11
                     /translation="MNKLLFVVALLLMGIAASAQHLGSEYRLKKVIPVAGRQGIAIDSN
                     YYYVSDTKVLYKYDKQGNIVAKNDQPFRHPEIANHFGDIDIYNGEIYCGIEKFEYGRGY
                     NIAVSIYDAETLQWKRDLPWSPESGQVEVSGLAVDREKNMVWMSDWVDSRYVYCYSLET
                     GQYYTKMQCRPTPYWCQGIFIADGKMLFTSDDGESLYNIPDNIYIADITEVHFTGLQDG
                     TEVVKETPFSVKLDKNGKPITRKGKIAAGAKAGRVELFREMSDFRRAGEIEGLAIDPVN
                     DDLVVLNNRGTLIVLGMSQGPFKEEGYTGEIHELYIYEKVK"
     CDS             complement(6174..7325)
                     /locus_tag="ctg16_106"
                     /transl_table=11
                     /translation="MKKSYLLNVLILCGALLVCTSTWAKAENDGTSKATGEATQANDGE
                     LTQKVNKLLSLLPKFSGYIQTGYNWGDKNGDNRSSFQLKRMRLIIDKQVSKTFDFRAQL
                     ECFSGSTDGTAYAKKVITVMDAYVNAHITSALHFRAGQYYLPLGFENYDISPATLETVD
                     FSNICYRMVCRNAVSTPNLIDYGRDLGIMAYGDFLPSKDKKFNYLSYQLSLTNGYLPTL
                     NDDNKSKDFVGRITVRPIEKLRIIGCYNWGEYKQLNAGTVVGNYQAMNRVITGAWYYDP
                     NGLDIRAEYGHIKSDDANVDEDGFYALAAYRFGKFIPVVRYDMYRDKANKTSANNKDNY
                     LIGCTYELIKDVKFQLNYIISDYTDKVDKGTGNSLQIMCLLKF"
     CDS             complement(7374..8315)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_107"
                     /sec_met_domain="HAD (E-value: 8.5e-16, bitscore: 51.7,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKLLTSSVIVLVMLFFTPCISAQTYRQIKGWSKEVNDRIETFL
                     NTTLTMKTRKVAVFDGDGTVFGQVPHYLADEALYRYADKNYKGKNDKVSKEKMAILNRM
                     VKNGDNVGKVYVEDRAHFLAGMTPEAVANLGYDCYVESYQGKFYPEMKQFLANLKEYGF
                     EIWILTASPEFLYQKFLSEELGIPDVNILGMKSVVVDGVLTNEIVLPIPQDDGKANVIP
                     TFIKTRPLVVGGNSRGDMDMLNQSCGLKIVINPDDKTVRGPEDGPMHGETVKSYWEKEG
                     ALIVRCNDVRNPKVRFHTGEWGIRENVSNPKN"
     CDS             complement(8321..9661)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 173.3; E-value: 2.3e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_108"
                     /sec_met_domain="MFS_1 (E-value: 4.3e-53, bitscore: 173.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWNFLKPEPHKPLLPKEEINHTYNRLRWQVFIGIFIGYAGYYLVR
                     KNFALAMPYLNEMGFDKGLLGVAISANAIAYGLSKFLMGGVSDRSSARKFLPLGLTLSA
                     LATLLLGTSFGISSIVSMFILQFLIGWFQGMGWPPCGRVMTHWFSHNERGTKMSIWNCA
                     HNVGGAAIGPMAAIGLTWFGSWQAGTFWFPAVVALIIVVIAYALIRDTPQSCGLPPIEE
                     YRNDYPKNYSAKSEEELTAKEIFFKYVLNNRILWFIAIANAFIYMVRYGVLDWAPTYLK
                     EAKGYDIREIGWAYFSYEFAAIPGTIICGWLSDKVFKGRRALTTMIYMALVALFVVVYW
                     QFSKTPLMDSICLIAIGFLIYGPVMLIGVHALDLAPKKAAGTSAGLTGFFGYFFGTALL
                     ANIGLGYIVQKWGWNGNFIALLIACALSFIFISFTYKEEQYLVKNKK"
     CDS             complement(10001..11221)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Respiratory_glycerol: Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_109"
                     /sec_met_domain="Fer4_8 (E-value: 3.4e-11, bitscore: 36.4,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 8.1e-05, bitscore: 16.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLQQHNISDNNFEQCIKCTVCTVYCPVAAVNPDYPGPKQAGPDG
                     ERLRLKKFNFYDESLKYCINCKRCEVACPSNVRIGDIIQAARIKYSEKKPTLRDFILAN
                     TDLVGTLSTPFAPIVNTTLGLKPVKAILDGVMKIDHRRTFPKYSFGTFEGWYKKQAAKQ
                     AAYPKQVSYFHGCYANYNNPQLGKDLVKVMNALGFGVQLLEKEKCCGVALISNGFINQA
                     KKQAKTNIASIRKSVLEKKIPVIATSSTCTFTIRDEYPHLLDVKNDDVRDQIELATRYI
                     YRLFSQQSAKLNFKKGEKKIKVAYHTPCHMEKLGWSYYSIELLKLIPNIELTVLDSQCC
                     GIAGTYGFKKENYKTSQDIGASLFKQIESCDFDVVVTDCETCKWQIEMSTSKRCEHPIS
                     ILANALE"
     CDS             complement(11230..12537)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Respiratory_glycerol: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 156; E-value:
                     5.5e-48)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_110"
                     /sec_met_domain="FAD_binding_2 (E-value: 1e-47, bitscore:
                     156.0, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLRGRVRTNIIFKGITMKFDTIIIGGGLSGLISGIRLSKQGQRC
                     VIISSGQSALHFSSGSFDLLNTLPDGNSVNNPIEAIEELAKQAPTHPYTKLGSNKFSQL
                     AKEAENFLKEVGISVKGDARKNHFRMTPMGTLKPTWLTLEDHMQGENADRISWKKISIF
                     NVTGFLDFYTQFIVDELAKIGTTCTTYLINFPALEHLRKNPTEMRSVNIARVFDNQENL
                     DEFARQIKAENGDCEIIALPAIVGLSRKDAVTYLQKEIGKPICLLPTLPPSVPGIQVQQ
                     QLRARFQEAGGVFMLGDIVIRAEKEDNRISRIYTNNHGDIPFSGKNVILATGSYFSQGL
                     IADTERVYEPIFDLDVTFSSNREQWYDRNAFAAQPYQTFGVRTDKDFRGLYKGEAIENL
                     YISGAILEGFNAIKEGCGAGVSILSALYVADRISSK"
     CDS             complement(12489..14114)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Respiratory_glycerol: DAO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Respiratory_glycerol: Fer2_BFD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_111"
                     /sec_met_domain="DAO (E-value: 1.6e-54, bitscore: 178.6,
                     seeds: 522, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 1.3e-08, bitscore:
                     28.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQHETTKPFDVIIIGGGATGAGTARDCSRRGLRVLLVERFDIST
                     GATGRNHGLLHSGARYAVTDQESAEECIKENMILRKIASHCVEETDGLFLTLPEDDIQF
                     QSKFVDACRQAGIRADVIDPKDALKMEPSANPNIIGAVRVPDGAVDPFRLTASNIMDAK
                     LHGAEVLTYHEVTELIREQDRIVGIKVLDHKTKETKSYYSSVVVNAGGIWGHNIAKLAG
                     VNINMLPAKGALLIFGHRVNNIVLNRCRKPADADILVPGDTICLIGTTSSKVPYEEVDN
                     MYVTPEEVDLLLREGEKLSPQLAQTRILRAYAGVRPLVASDDDPSGRNVSRGIVLLDHA
                     TRDGLEGFVTITGGKLMTYRLMSEWTTDLVCKKLNVTVPCTTASEKLPGSRENTEEISK
                     KIISVPLAQRNATINRHGDMADKFSENTPLDNSLICECEEVSVGEAKYALNELDVNNLV
                     DLRRRTRVGMGTCQGELCACRAAGLMSNMKKACTKRAKADLTSFLNERWKGMAPIAWGD
                     TLRESEYTAWIYEGVCGLTSSSKE"
     CDS             14629..15048
                     /locus_tag="ctg16_112"
                     /transl_table=11
                     /translation="MSFSERLLEVMKEKGYTKYRVAKDLNMSATTISNYLNNKTKPDTT
                     KLEVLSRLLGVNRIWLLTGDGEKCRGDVIGEDSCSPVRSVKEDDSELTRHLVEIMDKQA
                     SSLKAKDDQVSMLISTNELLLRKITPLLERLMEKL"
     CDS             15296..15394
                     /locus_tag="ctg16_113"
                     /transl_table=11
                     /translation="MTALEELVSLMFLAGLVDYFVVTRVSKIDIGY"
     CDS             complement(15476..15796)
                     /locus_tag="ctg16_114"
                     /transl_table=11
                     /translation="MEVSITPICRKDKINKKNEAPLALKISYNYDSRRKSLGTKINIDY
                     WDFENDSLKEETPNKEYIQLIIDSEIQKLNKKSENSLDKELQHATRYQSRNITLPVSTC
                     LQ"
ORIGIN
        1 cgggcttgat ttggaaatgg gggctgcctc tccttttaaa atggatgtcg gggtgtacgg
       61 tttggatatt gagggcttcg tgatggatag catactgatg gatgcttacg ggcaaggggt
      121 ggcattacgt tatgctgtga atgtgttcgg ggcaaaagat cagttggaag tcttgtcgca
      181 attcactgta gaagggtttg ccgaacacga tcaagtaaat gtacgcctgc gggaacggga
      241 aaataaggac ggggaaattt ttaatatcgg ggcgaatatc gctttccaag atagtgcctt
      301 tagcgtaagc atttctcccg atcctctcgt gttgggatac gtgccttggc aaataaaccg
      361 gggaaacttc atccggataa agcaaggcga gattccggct gcaaacttgt tgttattgag
      421 tgaggacaag cggattcggt tggtttcaga acaaggagtt aaccaagagc ctgaatctct
      481 cgtcgtggat ataaaagcaa tagacctcgg gcatatatct aaagtgttga cttttatccc
      541 ggatatgtcc gggttgttgg gaattgatct gcaaatgcat agtaaaaata aggtgatcga
      601 tgtgggggga aatatcacgg tcaatgaatt taattaccag caagaacgaa tcgggaatct
      661 ggatatgggg atacagtaca agttgtcgca acagacacaa cacgacgttg atttcacctt
      721 gtccgtggac ggggtacaag cactgttgac tcagggaaaa gtgatgaccg gggcggacga
      781 ccagaatatt gatttgaata ttggcatacc ggaacttcct ctacggttag cgggagcctt
      841 tacaccgccg ggaatgattc gcttgggagg aaatatggta ggtgctttcc ggatcaaagg
      901 tagtatgaat aatcccttga taaacggaag cttgtctttc cgggatgggg aggtggaagt
      961 acttccggta gggacgacct ttaaaataga tacctctgcc attaaagtac agaataattt
     1021 attggcattt aatcatttcg ggttgatagc cccgaataaa cagcgtttgg aattacaggg
     1081 gaatgttgac ttcgcttctt tctcgacgat caaaatggat gcctctgttt ccgctcgtaa
     1141 ttttcaagcc atgaaggtca aagagaacac ggaaacgatg gtttacgggc aattgtttgt
     1201 cgatgtgtcg gcaacattga aaggcatatt ggacgacttg aagattcgag ggaatattaa
     1261 tttgttggat aacagtgagg tgtactacac gttgaaatcc tcgcccctct cggtgaccga
     1321 ccggagtgtt gatctcgtgc gtttcgtttc tttccgagat agcacagaag tggcggaaga
     1381 ggacgagttg aaacaaatcc atacgatgag tttggatttg ctgatgtccg tgaatatagc
     1441 tccattggta aatcttaacg tgttgttgtc tgcgaacggg cagaaccggg tttctatcaa
     1501 cgggggcgga agcctgactt acacccttag tccggtagga gagagtcgcc tcgtgggacg
     1561 ttatgtgctt acgagcggaa tcgtgtctta tgggcttccg gtgatcgggc agaaggattt
     1621 cacgatacag gacggaaatt acgtggaatg gacgggtgat ttggcgaatc ccacgttgaa
     1681 cattatggct gccgaaacaa tttcggcaag cgtgacggat gatagccaga agtcacgtct
     1741 ggtgaatttc aaggcaatca tacgtatcac tagtacgttg gaaaagccgg atattacttt
     1801 tgatcttgcc gctgaaggcg atataacgat acagaatcag ttggcggcaa tgacgccgga
     1861 ggaaagatcg cgggaagcca tgaacatgat gatttacggt tcatactcgg gaccggggac
     1921 ggtggctaaa tcaaatgctt ccgacaacgc tattaataat ttcgtggaac gggaattgaa
     1981 ccagtggtcg agaaaacatc tgaaaaatat ggatttgacg ttcggcatca atacttacaa
     2041 tcaggtatcg gaagcgggcg aatcgaagaa aacggattat tcctatcaat tctcgaaacg
     2101 tctgttcaat aaccgggttc gggtgaaagt ggggggacgt atttccacgg ataacgaccc
     2161 agcggcaggt ggggtggagg aaaatttggt ggatgacatt gccgtcgaat atttgttcgg
     2221 gaagaatccg aatttctttc tgaagatatt ccggcacacg ggatacgaga gcgtgttgga
     2281 aggtgaagta acccaaacgg gtatcggtgt cgtgttacgg aagaatttcc agaagttccg
     2341 tgatattttc cggcggaaga aaaaagcaaa ggtggaatcg aaagaaacac agcaaacaga
     2401 gtatgaaaag tctgataaat agaatatata tacttgtagc tgcagctttg ttgctattga
     2461 gcgcatcgtg ttcgcagacc aaaaaactgg cggaaggcga agtcctgtac accggggtaa
     2521 aaaagatgaa aatagaaacg gcagaaggcg tgaagctgga aggagcgcag agttcggcta
     2581 tttccagccc tttgtcctat cccccgaata atcccttgta tgccccttac gtgcgttccc
     2641 ctttccctgt cgggttgtgg gtgtataatt ggaatatcaa gaaagaaaag ggtcttaaat
     2701 actggttgta caagaagctg gcaaagaaac cggtattaat atctgacgtg cagcccgaat
     2761 tgcgcttgaa agtggtggat aatgccgcca aggattatgg atatttcgga gtggaagcaa
     2821 gttacgagat tatcccgaac aagcgtaacc cgaaaaaagc caagatcagc tatcacgtga
     2881 atatccctaa gccttatatg ttcggggata ttgcattttg gggatggaag gggcgtatgg
     2941 atagcctgtt gcaaaggacg aaacaacgct gtcttttgat aaaaggaaca gaatacagtg
     3001 tctacgcgat ggaagatgag cgggcacgta ttacccagtt actgagaaat aacggttatt
     3061 attatttcca atcggactat atcgagtttc tggccgatac gacgcgggag aagcgggtgg
     3121 cggatattcg tgtcgccttg aaacacgggg ttccggctat cgctttgcaa ccctataaaa
     3181 tcggtaaagt ggagttggtt ctggaagaac ccgaccagtc gggaactccc gattcgttgt
     3241 cttacaagga aatcaacgtg aaatacatga agcccttggg agttaagccg aaagtcttgg
     3301 ctcgctcgat gcacttgttg cccgggaata cttattcgtt ccgtcggcag aaccggacac
     3361 agacaagtct ggcacgtctg ggaatcttta aatacacgaa cgtggacgtg acccggacgg
     3421 atacggctaa aacggaagag ttcgggaaat tgaatttcgg tattaacgcc gtgtatgatt
     3481 tgccgataga aacagagatt gaactcgatg tatcctcgaa gtccaataat ttacttggac
     3541 cgggattgat ttttagtatt accaacaaga atttgttccg gggaggcgag aatctttcat
     3601 tcaagctgaa tggcgcctac gagtgggaag tcggggataa gcaggggaat tccaaatccg
     3661 gattgatcaa ttcctacgaa ttaggagtga atgtcgcttt gtcgttgcca cgcctgctgg
     3721 tacctaattt cttgaaaagc acgaaggatt ttaccgagcg cacgcatttt caagtgggag
     3781 tcgatttcct gaatcgccat acttttttcc ggatgatttc gttcacgggg gccacgagtt
     3841 atgatttcca atcttcatac cgggtgtatc atagtgttac tcccttgaaa atcagttata
     3901 cccatttatt gcgcacttct tcggaattcg atgaaacgat ggagaacaac ccggcaatcg
     3961 caatgagttt caagaaccag tttattccat ccatgtctta tacttacacg tatgaccggg
     4021 gggcaacttc ccgtaacccg aaccgcttct actggcagaa tatgttgatg tcggcgggaa
     4081 atatattgtc ggctatacaa tacctgtccg gaaatcacaa gggggaaggg aaaacgatat
     4141 ttgggaacac ttattctcaa ttcttgaaag tgacttccga agtgattgtg tatcgtaaat
     4201 taaccgaaaa ttctttgatc gctacccggt tcatgggtgg aatagggtat gcctacggga
     4261 attcggaggt gatgccttat agcgagcaat tttatattgg gggtgccaat agtatccggg
     4321 cattcacaat tcgttctatc ggaccgggaa gttatcatca aaaaagtgat aacaaaacgg
     4381 cgtatctcga tcagaccgga gatattaagc tggaaggaaa tatcgagttg cgttttaaaa
     4441 ttgcgggaga tttgaatgga gcggttttct tggatgccgg caacgtatgg ttgttgagaa
     4501 atgattccaa acgtcctggt ggtgaattca agctgtccgg tttgctaaaa gagatcgctt
     4561 tgggaaccgg cttcggcttg cgttacgata ttggttttat cgtcattcgc ggggatttgg
     4621 gggtacctct gcacactcct tacaagaatc cggacaaaca tggatattat aatattccca
     4681 aattctggaa cgggttggca ttccatttgg ctatcggtta cccgttctag aataacagca
     4741 ggaatcatct atatatttgt cgtattcatt ccgatatacg gtgtttatat ttttgtaccc
     4801 ttgttaagta gaggcgggtg aaatgtgttg gaagaaaagt ggtattgttg ttgatgaaag
     4861 tcatttaatt gtaatattag aacattttaa tttgtacttt ctttatatca tctcctattc
     4921 aactcccatt caactcctat tcatctccta ttataaaggt atataaatag aaaattaatt
     4981 ggaattaaat aaaatttgac aatgctgaac tatatgatat gattataatt aattcttaga
     5041 agataactga acagggcaga aattgatatc gaaaaagaga ggaaaacagg aacggcctaa
     5101 aaaaagaaga ctgcccgagc gtgtcggaca gtccccccgt tgtttgaaat tattaacccc
     5161 gaaaactatt ttactttttc gtagatgtaa agttcgtgaa tttctccggt gtaaccttct
     5221 tctttgaacg gaccttgtga cataccgaga acgatcaagg taccgcggtt gttcaatact
     5281 actaagtcgt catttaccgg gtcgatagca agaccttcga tctcacctgc acggcggaaa
     5341 tcactcattt cacggaacaa ttcaactctt cctgcttttg caccggcagc gattttacct
     5401 ttacgcgtta taggttttcc gtttttgtca agtttcacac tgaaaggagt ttcttttaca
     5461 acttcagtac catcttgcaa accggtgaag tgtacttcag tgatgtcggc aatgtagata
     5521 ttgtcaggaa tgttgtacaa agactcacca tcatcagaag tgaaaagcat tttaccatca
     5581 gcgatgaaaa taccttgaca ccagtacggt gtaggacggc attgcatttt cgtgtagtat
     5641 tgtcctgttt caaggctata gcaatataca tagcggctat ccacccagtc agacatccaa
     5701 accatattct tctcacggtc aacagcaaga ccggatacct ctacttgtcc tgattccggt
     5761 gaccagggaa gatcgcgttt ccattgtaaa gtttctgcat cataaattga tacggcgata
     5821 ttgtaaccgc gtccgtattc gaatttctcg ataccgcaat agatttctcc gttataaatg
     5881 tctatatcac cgaagtgatt ggcaatttcg ggatgtctga atggttggtc gttctttgca
     5941 acgatgttac cttgcttgtc gtatttgtaa agaactttcg tgtccgatac gtaataataa
     6001 ttgctatcga tagcaatacc ttggcgtcct gccacgggaa tcactttttt caaacgatat
     6061 tcgctcccta gatgttgtgc acttgcggcg atacccatta gaagtagtgc cactacaaat
     6121 aataacttat tcatactaaa aatatttagg ttattaataa agttttttta taattagaat
     6181 ttaagcaagc acatgatttg caagctgttt cctgttccct tgtctacctt gtcggtgtag
     6241 tcggaaatga tgtagtttaa ttggaattta acatccttga tcagttcgta agtacatcca
     6301 ataagatagt tgtctttgtt gtttgcggaa gttttgttag ccttgtcacg atacatatca
     6361 taacgtacta cagggatgaa tttgccgaat ctgtaagctg caagagcgta gaaaccatct
     6421 tcgtcaacat tagcatcatc actcttgatg tgaccgtatt ctgcacgaat gtcaagacca
     6481 ttcgggtcat aataccaagc acccgtgata acgcggttca tagcctgata atttcctact
     6541 acagtacctg cattaagttg tttgtattca ccccagttat agcaaccaat aatacgcaat
     6601 ttctcgatag ggcgaacggt gatacgacct acaaagtctt tagacttgtt atcatcgttc
     6661 aacgtcggaa gataaccgtt cgtcaatgat aattgatagc tcaaatagtt gaattttttg
     6721 tctttactcg ggaggaaatc tccgtaagcc atgataccga gatcacgacc gtagtcgatc
     6781 aaattcgggg tagatacggc attgcggcat accatacgat aacaaatgtt tgagaaatcg
     6841 accgtctcca aagtagcggg agaaatgtca tagttctcga aacctagtgg caaatagtat
     6901 tgaccggcac ggaaatgcaa tgcagaagtg atatgtgcat taacatatgc atccataacc
     6961 gtgattactt ttttggcgta agcggttccg tccgttgatc cggagaagca ctccaattgg
     7021 gcgcggaaat cgaatgtctt tgaaacttgt ttgtcaataa tcaaacgcat acgtttcaac
     7081 tggaaagatg atctgttgtc gccattcttg tcaccccagt tgtaacctgt ttggatatag
     7141 ccggagaatt taggtaataa agaaaggagt ttatttactt tttgggtaag ttctccgtca
     7201 ttcgcttggg tagcttctcc tgttgcttta gaagttccgt cgttttcggc tttagcccat
     7261 gtagacgtgc acactagaag agcaccacac aagattaaca cgtttaataa ataacttttt
     7321 ttcataacaa tgttaaatta agttcatgta aaatataatt attcttctca gaattagttt
     7381 ttagggttgc ttacattctc tctgattccc cattcgcccg tgtggaaacg tactttcggg
     7441 tttctcacgt cgttgcatct gacaataaga gctccttcct tttcccagta cgattttacc
     7501 gtttcaccgt gcatcggacc gtcttccgga ccgcgtaccg tcttgtcgtc cgggttaatt
     7561 acgatcttca gaccacagga ctggttcaac atatccatgt cgccccggct attgccacct
     7621 actaccaacg ggcgggtttt aatgaatgtc ggaataacgt tggcttttcc gtcgtcttga
     7681 ggtatcggga gcacgatttc gttggttaat actccgtcaa ctacgacaga cttcatcccg
     7741 agaatattca catcagggat tcccaattcc tctgataaaa atttttggta taaaaactcg
     7801 ggagaagctg tcagtatcca aatttcaaaa ccatattctt tcaaatttgc aagaaactgt
     7861 ttcatctccg ggtagaattt cccctggtag gattccacgt agcaatcgta tcctaaatta
     7921 gctacggctt cgggagtcat cccggcaagg aaatgcgcac ggtcttccac gtagactttt
     7981 cccacgttat ctccattctt caccatccgg ttcagaattg ccattttctc tttggacact
     8041 ttgtcattct tgcccttgta gtttttgtcg gcataacggt ataaggcttc gtctgccaga
     8101 taatggggta cttgtccgaa cacggtgcca tccccgtcga atacggcgac tttacgggtc
     8161 ttcatggtta aggtcgtatt caagaaagtt tcgatgcggt cattgacttc ttttgaccat
     8221 cccttgatct gacgataggt ttgtgcagat atgcaagggg tgaagaatag cattaccaga
     8281 acgataacgc tactcgttaa aagtttcttt ttcatgtttg ttactttttg tttttaacca
     8341 aatattgttc ttccttgtaa gtaaaactga tgaaaataaa cgatagtgcg cacgcgatta
     8401 gcagggcaat gaaattgccg ttccatcccc acttttgcac gatgtatcct aaaccgatat
     8461 ttgctaataa ggctgtaccg aagaagtacc cgaagaatcc cgtcaggcct gccgaagtcc
     8521 cggcagcttt cttgggagct aaatccaagg cgtgaacccc gatcaacata accggtccgt
     8581 aaatcaggaa tccgatagca atcagacaga tactgtccat gagcggagtc ttgctgaact
     8641 gccagtacac gactacaaac aaggctacga gagccatgta gatcatggtt gttaatgccc
     8701 ggcgaccctt gaataccttg tcactcaacc aaccgcaaat gatggttccc gggatagctg
     8761 caaactcgta tgaaaaataa gcccagccga tttctctgat gtcataacct ttggcttctt
     8821 tcagataggt cggagcccag tcgagaaccc cgtaacgtac catataaatg aatgcgttcg
     8881 caatggcgat aaaccaaagt attctgttgt ttagcacgta tttgaagaaa atctctttag
     8941 ctgtcaattc ttcttctgat ttggcactgt aatttttggg gtaatcgtta cgatattcct
     9001 cgataggggg aagaccacaa gattgtggcg tgtcgcgaat aagcgcgtaa gcaataacaa
     9061 cgataatcaa tgccaccacg gcaggaaacc agaatgttcc ggcttgccat gaaccgaacc
     9121 aagtcaaccc gatggcagcc atgggaccga ttgccgcacc tcccacgttg tgggcgcagt
     9181 tccaaataga cattttcgta cctctttcgt tatgggagaa ccagtgtgtc atcacgcgtc
     9241 cgcaaggagg ccagcccatt ccttggaacc aaccgatcag gaattgcagg ataaacatgg
     9301 aaacgataga agagataccg aagcttgttc ctaacaataa ggttgctaat gccgagagag
     9361 ttaatcctaa aggcaagaat ttgcgagcgc tactccggtc ggaaactcca cccataagaa
     9421 atttggaaag accgtaagcg atggcgtttg ccgagatagc cactcccaaa agtcctttgt
     9481 cgaagcccat ctcgttcaag tagggcattg ccagggcaaa gttctttcta acaaggtagt
     9541 aacctgcgta tcctataaag ataccgatga aaacttgcca ccgtagacga ttgtacgtgt
     9601 ggttgatttc ttcttttgga agtaaaggct tgtgaggctc aggtttcaaa aaattccaca
     9661 tgttattaga ttttattttt ataattatta atcaagtaca cttttgtata tattggattt
     9721 taaaagtatc cggaagtcag gaaaaggaca tttcaatatg gcaatatttt tctgctccat
     9781 ttgttcttgt ttttatgatc ctctattttt ccttgaatcg aatgaattcg aaaacgtttt
     9841 ctttcttatt cgtaataaat atctttcaat tcacaacaaa aataggaata ttgattttta
     9901 aatcaaaata attttcaata aaattacgtt ttccttttta ttttattttc cttgtttttg
     9961 taataaaaac attttacact ttagagtgat gacgtgcgtg tcattctaag gcgttggcta
    10021 atattgatat aggatgctcg catcgttttg atgtggacat ttcgatttgc catttacagg
    10081 tttcgcaatc ggtgactacc acatcgaaat cgcaactttc tatctgtttg aacagggaag
    10141 ccccgatgtc ttgtgatgtc ttgtagttct ctttcttgaa accgtaagtg cctgctattc
    10201 cgcaacattg agagtctagt acggtcagtt caatgttcgg gatgagtttc agcaactcga
    10261 tggagtaata agaccagccc aatttttcca tgtggcaggg ggtgtgatac gccaccttga
    10321 tttttttctc gcccttcttg aaattcaatt ttgcactttg ttgactaaat agacgataaa
    10381 tgtaacgtgt tgctaattcg atctgatctc ttacatcgtc attcttcacg tccaaaaggt
    10441 gaggatattc atcccgaatc gtgaacgtgc acgtggacga ggtggctatt accggaatct
    10501 tcttttcgag tacggacttt cgaatcgaag caatatttgt tttggcttgt ttttttgctt
    10561 ggttgatgaa gccgttggaa attaatgcca ccccgcaaca cttctctttt tccagcaatt
    10621 gtacgccaaa accgagggcg ttcatcactt tcacgagatc ttttcccagt tgtggattgt
    10681 tatagtttgc gtagcaaccg tggaaataac ttacttgctt gggataggcg gcttgttttg
    10741 cggcttgttt tttataccat ccctcgaacg tcccgaatga atatttcggg aatgtacggc
    10801 ggtggtcgat tttcatgacg ccatcaagaa tcgccttcac gggtttcaaa cctaatgtgg
    10861 tgttcacgat cggggcgaac ggggtggata gtgtccccac taaatccgtg ttcgctagga
    10921 tgaaatcacg taatgtcggt ttcttctcgc tatatttaat gcgggcggct tgtatgatgt
    10981 cgccgatcct cacgttggaa gggcatgcca cctcgcatcg tttgcaattg atgcaatatt
    11041 tcagcgattc gtcatagaag ttgaatttct tcaagcgcag gcgttccccg tccggtcctg
    11101 cctgtttagg acccgggtaa tccgggttga cggctgccac ggggcagtag actgtacaca
    11161 cggtacattt gatacattgc tcgaaattgt tgtcgcttat attgtgttgt tgtagattca
    11221 taacttcttc tatttacttg aaattctatc tgctacatac aatgcactca ggatggaaac
    11281 tccagccccg catccttcct tgatggcatt aaagccttcc agtatcgctc ctgatatata
    11341 aagattctcg atagcttctc ccttgtatag cccgcggaaa tctttgtccg tcctgacccc
    11401 gaaggtttgg tagggttgtg cggcaaacgc attccggtca taccattgtt cccggttgga
    11461 cgagaaggta acgtccaggt cgaagatcgg ttcgtaaact cgctccgtgt cggcgattag
    11521 tccctggctg aaataacttc ccgttgccaa gattacattt ttgcccgaga acggtatgtc
    11581 cccgtggttg ttcgtgtaaa tccggctgat ccggttgtct tctttttctg ctcgtatcac
    11641 gatgtccccg agcatgaaaa cgcctcccgc ttcctggaat cgggcacgta gttgttgttg
    11701 tacctgtatg cccggtacgg aagggggaag agttggcaat aagcagatcg gtttcccgat
    11761 ttccttttgg aggtatgtca cggcgtcttt cctgctcaat cccacgatcg ccgggagggc
    11821 gatgatttcg caatccccat tttcagcctt gatttgacgg gcgaactcat ctagattctc
    11881 ttggttgtca aataccctgg cgatattcac ggaacgcatc tctgtcggat tcttccgtaa
    11941 gtgctccagg gcgggaaaat taattaaata ggtggtgcaa gtggtgccta ttttagccaa
    12001 ttcatcaacg atgaactggg tgtaaaaatc aagaaagccc gttacgttga agatgcttat
    12061 tttcttccat gaaatccgat cagcgttttc tccttgcata tggtcttcca aggtaagcca
    12121 tgtcggcttt agcgtaccca tcggggtcat acggaagtga ttctttcggg cgtcgccttt
    12181 cacggaaatt ccaacctctt tcagaaaatt ctccgcctcc tttgctagtt gggaaaattt
    12241 attgcttcct aatttggtgt aaggatgtgt gggtgcttgt tttgccaatt cttcgatcgc
    12301 ttcgatcggg ttgttcacgc tatttccgtc cggtaatgtg ttcagtaggt cgaaagagcc
    12361 ggatgaaaaa tgtaaagcgc tttgcccgga agaaatgata acacagcgtt gtccttgttt
    12421 tgacaagcgt attccggaaa ttaaaccgga cagaccgcca ccgatgataa tagtatcaaa
    12481 tttcatagtt attcctttga agatgatgtt agtccgcaca cgccctcgta gatccatgcg
    12541 gtatattcac tttctcgtaa cgtgtcgccc catgcgatag gtgccatgcc tttccatctc
    12601 tcgttcaaga aagaagtaag gtcagctttt gctctttttg tgcaggcttt cttcatgttg
    12661 ctcattagcc cggcagcccg acaggcgcaa agttcgcctt ggcaagtacc catgcccacg
    12721 cgggttcttc tccgtaaatc gacaaggttg ttcacgtcca attcgttcag tgcgtatttc
    12781 gcctctccca cggacacttc ttcgcattcg caaatcaagc tgttgtctag aggtgtgttt
    12841 tcggagaatt tgtccgccat atccccgtgg cgattgattg tcgcgttgcg ttgagcgaga
    12901 gggacggata taatcttttt gcttatttct tcggtgttct ctcttgaacc gggcaatttt
    12961 tccgaggcgg tggtgcaagg aacggtgaca tttaatttct tgcaaaccaa gtcggttgtc
    13021 cattcggaca tcaaccggta ggtcatcaat tttcccccgg taatggtgac gaatccttcg
    13081 agcccgtctc tcgttgcgtg atccagaagg acgatacccc tgcttacgtt tcgtccgcta
    13141 ggatcgtcat ctgacgccac taacgggcga actcccgcgt aggctcttag gatgcgtgtc
    13201 tgagccagtt gcggggataa tttctcgcct tcccgcaata gtaaatctac ttcttccggg
    13261 gtgacataca tgttatctac ttcctcgtaa ggaactttgc tggaagttgt tccgatcaga
    13321 cagatcgtgt cgcccggcac gagaatatcg gcgtcagcag gtttccgaca tctgttcagc
    13381 acgatgttgt ttacccggtg accgaagata agcagggctc ctttggcagg taacatattg
    13441 atattaaccc ccgctagctt cgctatatta tgtccccata tacctcccgc attaacaaca
    13501 acggagctgt aataggattt tgtttctttt gttttgtgat caagtacttt gatgcccacg
    13561 atccggtctt gttcccggat gagttcggtg acctcgtgat aggtaagaac ctcggcgccg
    13621 tgaagttttg cgtccatgat gttggaggcg gttaggcgga aggggtctac ggctccgtca
    13681 ggaaccctca cggctcctat aatgttcggg ttggcagaag gttccatttt caatgcgtct
    13741 tttggatcga ttacgtcagc ccggatgccg gcttggcggc acgcatctac aaatttggat
    13801 tggaattgaa tgtcatcttc ggggagagtc aagaagagcc catctgtttc ttccacgcag
    13861 tggctggcta ttttacggag aatcatgttt tccttgatgc attcttctgc tgactcttgg
    13921 tcggttaccg cgtagcgggc accactatgt agcaacccgt gattgcgtcc cgtggctccg
    13981 gttgaaatgt caaatctctc caccaaaagc acccgtagtc ctctgcggga acagtctcta
    14041 gcggttccgg ctcctgtagc cccgccgccg atgatgatca catcaaatgg tttggttgtc
    14101 tcgtgctgtg tcatatccaa aagattttat atcacaaagg aaagaagaaa acgaaataaa
    14161 acaaaacaaa atcgcaatta ttttatctaa aaacgaaact aaatgaaatg ttttgtattc
    14221 gattctcttt tgaagcgttt tttatttctc tattgaggtg aaaaaaacga aactgtttta
    14281 tacctattat ataataggag tggaagggga ttcgtgtggt atattccggg gggatttata
    14341 aggattttgt tggggaatat gctgggattt ccagagtgtg tttgaaatga tgccttgtga
    14401 tcgtgtgtga aaaaaggaga agacaaagag cgttaacggg ataaatgtct ctgtcttctc
    14461 acatcaccaa ccgattaact aaccccaaca acttggggat ttcaccaata atcgctatat
    14521 ttgtaacaaa cgatatgcaa agataatgca aatttggaag aatgcaaagt caaattggat
    14581 tatattttgc tagaaagtaa aatttaaatt aattctaaat aaaaggatat gtcattttcc
    14641 gagagattgc tagaggtgat gaaagagaaa gggtacacga aatatcgtgt ggcgaaggat
    14701 ttaaatatgt cagctacaac tatttcaaat tatttgaata acaagactaa gcctgacacc
    14761 acaaaattgg aagtattgag tcgtctattg ggagtgaacc ggatttggct tctgacaggg
    14821 gatggagaga aatgccgggg tgatgtgatt ggagaagatt cttgttctcc tgttcgttct
    14881 gtgaaagagg atgatagcga gttaactcgc catttagtgg aaattatgga caaacaagct
    14941 tcttccttga aagcgaaaga cgatcaggtg tccatgttga ttagtacaaa tgaattgttg
    15001 ttgcgtaaga ttacgcctct gcttgaaagg ttgatggaga aactttaatg atgtaatatt
    15061 ggaatactat tttacgatcg ttacaagtgt tgaagaatgg atttttcgat cgttcgtgaa
    15121 gtagtttttc tattttcttg aaaaaatacg attaaaataa attttttttt gagataaaat
    15181 cttcaatgaa aagtgtggta tttaagagcg gcgtcaagcc atacccgtgt acgggtgaaa
    15241 ccggctcaat gggaaaatct gtgtgtttta tttttgcttg ataaaattat ttttcatgac
    15301 tgctttggaa gaacttgtat ctttaatgtt tcttgcaggt ttggtggatt attttgtagt
    15361 aactcgagtc agtaaaattg atatcggcta ctaggtttac tagttttcat gacgagtaag
    15421 tgatccatga tttcccttta cgtggtaagg tttttgacct ggtaatcaaa cgtcgtcatt
    15481 ggaggcatgt tgaaacgggc aaggtgatat tccgggactg gtatcttgtg gcatgctgga
    15541 gttctttatc gagagagttc tcggattttt tgtttaactt ttgaatttcg gagtcaataa
    15601 tgagttggat gtattctttg ttgggtgttt cctcttttaa ggaatcattt tcaaagtccc
    15661 aataatcaat attgattttt gtccctaagc tttttcttct actatcatag ttgtaactta
    15721 ttttaagggc aaggggtgct tcattttttt tgttgatttt gtcttttcta caaataggtg
    15781 ttatacttac ttccataaat tttcttgatt tatagaactg gtatttggct ttattgaaaa
    15841 aatggggacc aaataggggg acaaataaga ggcaaaatcc ctatttttta tctaaaatcc
    15901 ccttttgtca cttgaaaaat aagaatattg cattgaaagg gaaggtttgg taactaagaa
    15961 acattcttat tgtaactatt taaataatag ctatataaaa caaaagagca gcccttttac
    16021 agactgcttc tcctgagctg ttaatgggat ttgaacccat gacctcttcc ttaccaagga
    16081 agtgctctac ccctgagcta caacagcaat ttg
//
