LOCUS       c00003_NZ_VICB..       23490 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_VICB01000003.1 Actinomyces johnsonii strain CCUG 34287
            CCUG34287T_0000003, whole genome shotgun sequence.
ACCESSION   NZ_VICB01000003
VERSION     NZ_VICB01000003
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:34:48
            Original ID  :: NZ_VICB01000003.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 384334
            Orig. end    :: 407824
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23490
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[394334:397824]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..23490
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23490
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(1422..2327)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hydrolase_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_308"
                     /sec_met_domain="Hydrolase_4 (E-value: 1.7e-22, bitscore:
                     74.5, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIATLLNEHSIGLASYSEVSIESGRAPITLSIWEAEQDAAPTVV
                     FVPGTMTHPLFYSPFLDAVSRHGYHVVGVHPLSHGRSPRIIHRFTLDDMIGNVRDAVGY
                     ACARFPGAVGLMGSSQGGILTLLAAGGEHRIRTAFPHNVLFTPLRESLSVTRFPNALGV
                     AYPVIRRVIALAGRVLPGLQVPMSCYLDVSKVFSEREWRDEFYRDPLGRTAYPVSFLSS
                     LFTTDMSVLVDGSIACPVVAFVSTGDPLFTLGYSRLVYERLVAPQKRLIELPAGHHLIL
                     NEKAERVTPTILATLDDYLR"
     CDS             complement(2484..3332)
                     /locus_tag="ctg3_309"
                     /transl_table=11
                     /translation="MDQLITPAIWCDAADDEAARFYADVFREGSVVEQTPGLAATVSIH
                     GFRLSLINGGDQYAPNPSISCILNFDPLLFGDEDQARTYLDELYERLSAGGVLMELGEY
                     PFSPRYAWVRDRFGMTWQLMLTDPAGEPRPFILPSFMFGGTNHANAEEATEAWIALFDD
                     AHRGALRRYEEGGPMEAGTVMFTDFTLRGTWMAAMDSGAFHDFTFTPGVSMIVSCRDQE
                     EIDRYWTGLSAVPEAERCGWCVDRWGVSWQVVPHNIAELMADAATREKILQMGKIDLTR
                     L"
     CDS             complement(3454..5718)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_310"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 9.6e-12, bitscore:
                     40.3, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRIKSSSISNSFFSTLLRLCSIITLLSLISIATSLPLSPPASAE
                     VKTNNLIRATLLGDSYSAGNGAGDYYGPKESYRSHNNWAHKYTRWLNDQGAPTTLENLA
                     YSGSVTSDVLHTDGKTNQIDKMSADTNLVMFTIGGNDVNFSDIVQQCFALGMRDAKTCK
                     EKVTNANTQLENVKTNTLTILQQIDDKLTNDAQVILVGYPRLASNREYILKDDGVEYNA
                     GAGVRSLSDSSMQIQSTLVQEWNNSHPSLKVTYIDGVIDTFDGHEPDPSVKDRNPHRWI
                     NEFFETEGQTDENGNIQSKSSWDTNEFYHPNLVGHDEIAKLIAKKVGIPSFDNPMLGVK
                     GDIDIVFAIDSTGSMKNNVGALRARVSTIIKQTQQGASSYRFALVDYKDHPDFNANNYL
                     ARTDVDFTSDGPTLEKGLDSLTYEGGNFGNTNASVYSGVMQAVNMKWRNGVKKIVVVIG
                     DAPPRDPEPGTGYTAASVAKAAYEVDPVSVYGIDTGHLSSTEFRTLVTSSSGTTANASS
                     PDQVSDLVNNAINSELNKPFAWIQGPYVAKVGDSVDIDAAASHAVSGSLTSYEWDFNGD
                     GVYDETANSPRITHTFTEEFSGVIGLRVTQSDGQAAVATTQVDITDDGDSTPRDQDNCP
                     DVYNWGQSDFDNDGVGDECDPDPGFPTEDKPGVCVVGENCPPDGGAPSVQPTPDPNSGS
                     VPTPAVVPEPTKAPTAAPTTTASRRSLSNTGPRAGRLTTLAVIGMLTGAAVLHYRRRVI
                     S"
     misc_feature    complement(4459..4461)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     misc_feature    complement(4522..4524)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     misc_feature    complement(5176..5178)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             complement(6749..6946)
                     /locus_tag="ctg3_311"
                     /transl_table=11
                     /translation="MALFIDHAGSHRWAKDPKPSATDPWIGRHGGTETPDDMILNIDSD
                     IGSHDTDPFRNLNAADLWHD"
     misc_feature    complement(6776..6778)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             complement(7319..8473)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 137.4; E-value: 1.9e-42)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_312"
                     /sec_met_domain="MFS_1 (E-value: 1.3e-41, bitscore: 137.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRKLSLLGFAVMFLIGSDTFVVAPLLPSLAKAFDVSTTQSGWLV
                     SVYAIGYALTGLVSGPISDRGNRRIILTLGMVVFALATAACAVSAGFWTMFTFRFITGG
                     AAAIAAPQVWALIPALVGPDQKHVLRVMGYATAGLSIAQVVGVPLGSLLAIIDWRIVFP
                     IIGACSLGLTVILWYQIPDIRPTAATKKVPYLTLLHAPQAFTRFLSYLAYTLAFFTVFT
                     YAPTWLEDGLGTSKVTVALIVLAGGIGNTIGSLFGVRLTGRMTPVRAIYLSATVMGIAY
                     LTLAVSPPPIVVGLVFLPLFACGGAMLSVRMLHLQQLDSTARGTISTLTSAVMYLGTTV
                     AGLIGGPLLTLTGNFTAIGITAFLLSTASALMIRLSELGEEVNQ"
     CDS             8580..8939
                     /locus_tag="ctg3_313"
                     /transl_table=11
                     /translation="MRISEAARRAGTSPRMLRYYEAEGLLTPTRRDNGYRGYGVEEVLA
                     ARQIVTLSHAGFPLSLIRTVLPCATESGALRACPSVAPELRRWLRDVEEQIEVLSSGAE
                     VIRSFLDNLHDVASG"
     CDS             9114..9941
                     /locus_tag="ctg3_314"
                     /transl_table=11
                     /translation="MSEKPADSTTSTDLPLPYADRPVASAPGHWVLARAGKRVLRPGGA
                     ALSAAMLSHAGLAGADVVELAPGLGRTAAEIIKDRPASYTAIDRDPDAARRVAAVVGDL
                     GSVRQGEAADTGLDDASADVVVGEAMLTMQGDKGKAAIVAEAARVLRPGGRYAIHELGV
                     TPDDIDEEYYTELRRDLARSIHVNARPMTAAAWKELMEDAGLVVDWVDTAPMALLKVGR
                     NIRDEGLGGFLRIARNVAADKELRGRVQEMARTFKRYEKNMVGIALVAHKPES"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_315"
                     /sec_met_domain="Fer4_7 (E-value: 9.4e-11, bitscore: 36.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.7e-08, bitscore: 27.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.6e-23, bitscore: 77.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.7e-06, bitscore: 23.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIELEIWRQDGPRARGFFESHVVEDAEPQMSLLELLDRLNDQII
                     EAGGEPVVFESDCREGVCGACGFLVNGVPHGPMDTTPACRQHLRAFPGVTHFRLEPWRS
                     AAFPVIRDLAVDRTALDELIRVGGTVDVAAGTAPDADDVAQGHLQAERALDFAACIGCG
                     ACVAACPNGAAALFAGAKLAHLSLMPAGRIERGRRARAMTRELDELFGPCSEYGECVPA
                     CPAGIPIEAIALLNREVLRAGLRGATRDD"
     CDS             complement(10753..12714)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.1; E-value:
                     1.5e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_316"
                     /sec_met_domain="FAD_binding_2 (E-value: 1e-58, bitscore:
                     194.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.2e-34,
                     bitscore: 112.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSASVPRAVGGLYDIGEDLDAHLPDCPPEQAWERRRDEYRLVNPA
                     NRRKLTVIVVGAGLAGAGAAAALGRLGYRVECFSLHDAPRRAHSVAAQGGINAARARKV
                     DGDSLTRFVKDTVKGGDYRGREADVVRLGLESGRVIDHMEAIGAPFAREYGGQLATRSF
                     GGVQVSRTYYTRGQTGQQLEIACAQALQEQIAAGSVHMHTRTEMLDLIVADSRAQGIVA
                     RDLLSGEVRAHTAHAVVLATGGYGSVYHYSTLAMASNATATWRAHRRGAAFASACMVQF
                     HPTALPVSSHWQSKTTLMSESLRNDGRIWVPVRPGDERPPNDIPEDERDYYLERKYPAF
                     GNLTPRDVASRNAREQIESGRGVGPLRNSVYLDFRDALERLGKETIASRYGNLFEMYLD
                     ATGEDPYEVPMRIAPGAHFTMGGLWADFDQMSTIPGLFVGGEASNNYHGANRLGANSLL
                     SASVDGWFVLPLAVPNYLARLVGSKPLSLDAPEALQTVADTRKRIEALMAVGGAHRPVW
                     FHRRLGEVLYAGCGVSRSEAGLLRALEEVRALREEFWADVKVVGGQARLNQELEKALRV
                     ADFLELAEVMILDALDRRESAGAHFREEYATQGGEAQRNDETWCSVSAWQTGPDGGHTR
                     RTEPLSFSLVPMQVRDYR"
     CDS             complement(12711..13490)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_317"
                     /sec_met_domain="SucD_FumR (E-value: 2.6e-06, bitscore:
                     21.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAATSTAVRTPEAAQPVGDALPPRRRRRVPVWASQRVLKATMAIT
                     GTIMALFVVVHMVGNLKVLAGPEAFNGYAAWLRQVAYPLLPHEGLLWAMRLALGACIAA
                     HIAAGIALWRRARDARGAFRRRALPARTIGARSMLVTGALIGVFVLIHILDLTIGRLIA
                     PESFQAPTTSNGEMQVSAYHNLVASLSRPGMAVFYSLVMLALSLHLAQGLWNVVIDLGG
                     TGPRLRKVCRAVALVVALTIAVVNGLLPVLICTGVIG"
     CDS             13718..15457
                     /locus_tag="ctg3_318"
                     /transl_table=11
                     /translation="VPVEVSPVLPGAPVSPRTSGPSRRQVLTGGATGALAVLLAASGCS
                     RKADGPRLLTIPREDTGTFIRNFNPFTTNSAPMTGQAIYEPLLIVNPLSGEVTPWLADS
                     WAMSDGATALTFYLRPGVTWSDGRPLVAKDVVTTFAVHRAVTGGYDYLDSVTVNNATAV
                     TLTFTRPYSVALQELGSQLIAPDHVWSTISEPAEYPNPEPVATGPFTRVANFQAQSFDL
                     MPNPTYWGNNRQDNAGASSTGRTADQDSLPGIRMLAFAGNDSANLAAVSGDVDWAPQYM
                     ADIQTAYIDKDPAHRHYWFPGADSTIQWTLNTTKAPYNDPAFRKALSQAIDRKTICATG
                     MSGYTQPADPTGLSESFQTWKDPAVAAAPLCTYDKAAATAALDAAGYVLGADSKRLGLD
                     GKPLTLTIQVGSTSSDWLSVARIIVQNLADIGISATVDSSDWTEVTAALETGTFETAVC
                     WSSLGATPYTYYEATMSTQKVKPIGTHALENYHRFGDEQATALLSQFAATTDQAGQIEI
                     CRQIQQRYADQLPVIPLFPGPVWGAYTDEHFTGWPNRDNPYASLSTRAATTVLVLNALR
                     PRG"
     misc_feature    13742..13744
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             15601..16596
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 130.3; E-value: 2.3e-40)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_319"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.5e-39, bitscore:
                     130.3, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTYILKRLGYYLLALWASVTLNFLLPRLMPGDPVSRMFARSGARL
                     TETQALQLRRLFGLDDAPLWQQYLRYLRSVLTGDLGVSISRFPAPVSEVIGSQIGWTVL
                     LGGVALVIAAGVGSLLGILAAWRRGGVADSILVPLLVFLGSFPYFWLAMGSLYLLGMGL
                     GWFPLSHAYTAGTVVDWSSPAFLADVAQHLALPALTIVAVSLGGWALGMRNTMIATASQ
                     DYILLAEAKGLSRSRIMLRYAARNAMLPTVTSIGMSLGFIVGGSMLTEVVFAYPGIGYQ
                     LFSAVGALDYPLMQGIFLTITAAVLAANLLVDLVYIRLDPRVRASGQGES"
     CDS             16593..19193
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 55.2; E-value: 2.5e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_320"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.7e-16, bitscore:
                     55.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPARRYLQQRTRRRAQRRGSPLTGLLASLTRSRRARTGVVILAL
                     LIIAALLAPVISPGDPARITGAPAAAPSPAHWFGVTPKGQDVLAMTLWGARSSLAVGLG
                     AGLLATLVALVVALASAYLGRAVDGLLSVVTNVFLLLPGLPLLVVLAAYMPPGWGSTLI
                     VLIVTGWAGAARVLRSQAMSLRGTDFVEAAVVSGERPARIMMGEMLPNMASVVMSTLLG
                     CVNSAIGAQAGLEFLGLGRSDSVSWGTNLYWAATDGALMTGRWWTFVPSGLAIALVAYA
                     LALINAGVDEATNPGLRRAASGAPSRQRPPTPAAEPDSGNRAVPEPVLRIEDLSVEYDA
                     GDRSSGGGCVIGVDRFSLAVGRDEVMGLAGPSGCGKTTVAAAIMRLLGPAARITSGRVL
                     VGGRDVLALEAGELCRLRWREIAIVPQAAMNALNPVMTIGEQIADVLTTHDGLRRRTAR
                     ERAAELLESVGIPSGRLRAYPHQLSGGQRQRVVIAMALTLRPRLLVLDEPTTALDVVVQ
                     REIMELVLDLKARLSFSVLLITHDLSLMAGVCDRIGVMEAGRLVEEGPARRILTSPAHP
                     ATQALVSGLPPRPGRRTKTSAEPILEVEGLRMDFPAGGLLSRRTIRALDGVDLTLHRGE
                     ILALVGRTGSGKSTLARVIARLETPTAGRLLLEGRDVLAEEPRRASRSYRRRVQMVFQD
                     PFASLNPAHTVGHALGRALAVHRGTTEPGRGSAELLDAVGLEPELLGARPHELSGGQRQ
                     RVAIARALACEPEVLVADEPTSMLDAPLRAGVLDLLLRLRRERDLSILYITHDLASARY
                     LADTTVVLQAGRLVETGPTAELMKHPVHPCTRLLLSSALENRREVWGYDGAPGV"
     CDS             complement(19293..20882)
                     /locus_tag="ctg3_321"
                     /transl_table=11
                     /translation="MVLGRVSRRALLVGGWSILGVPVLAACLDRRKKGGSSDGSNSSSA
                     GASGGSGQGVTRTVTTVGATLKVTVGPAAVSDDVMVVPMAVHLDKMGSGGLSSDGKKFD
                     VHLAWSGTGNFTGADGVRLVDFDAGTVQETFKASSESTELTKEEPDATLHALFKPVDAT
                     TVNVLVPESGLFEGVPVVRDGKLSEEAKKALEDVYDTESSPDPVALETFTASVDGASDT
                     RVTGKSVVINLASDVLFDSDSADLSAQADATLKKAADQLSTYPGGEVSIVGHTDDVADD
                     AHNLDLSKRRATSVSDRLGQLTNMSAFSVSTDGKGESTPRVPNDSDGNRQLNRRVEITL
                     VPTQASSSTSSPDASKGTGHGSGDLPKAEGPVAKGSEGVTVKRDGRQDELTFVLTEVTR
                     RGKYLVGEVKATGGPGGTQTGPADWLQPTQILGSARGEDDNRLTSAVTGLSLLTAQTRY
                     YPADYTAAEGTHHPLSEITADNQLGAGDTTTLTVVWPDTGQDTVTLDLQPAQHSTPSPN
                     NPFRLTDIPVKR"
     CDS             complement(21098..22081)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hexapep_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_322"
                     /sec_met_domain="Hexapep_2 (E-value: 9.9e-16, bitscore:
                     52.0, seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTRSAWGLGLATVTDDGNTLDVWYPRPVLGDEPEDGHADLLSTL
                     SAMERRDEARGVHTTVVRTWADLDDAPQTVAGAYLRLHALSHRLTKPNTVNLDGIFSRL
                     PNVVWTSAGPCRAEDFETTRTRLRAALGRPVQVHSVDKFPRMTDYVLPSGVRIGNASNV
                     RLGAYLSEGTTVMHAGFVNYNAGTLGRSMVEGRISQGVIIGDGSDVGGGASTMGMLSGG
                     GRQRVALGERCLLGANSGLGIPLGDDCVVEAGLYLTAGTKVSLMPQGGVVPGSHGLFKE
                     PRVVSARELAGASNVLFRRNSQSGAVEALARGGKGIELTSPLQANQ"
     CDS             22143..22877
                     /locus_tag="ctg3_323"
                     /transl_table=11
                     /translation="MARTTIHLMRHGEVHNPEGLLYGRLPGYHLSTLGHQMAQQVADVL
                     SASGHDITRVITSPLERARESGAPTAAAFGLTPTTDARLIEAGNRFEGVAVNRNRWILA
                     HPANWSNYVNPLRPSWGEPYREIVERMRGAVVSALGIAEGHEALLVSHQLPVWSLRLFL
                     EGRSLAHDPRRRQCALASLTSLTFEDRTLVGLAYWEPAGDLLRQARDMVPGTSAARAAT
                     GRPLHTDSDNSDNSANSTEAAR"
ORIGIN
        1 tcctgcgcta ccgcggctac ccgatcgagg agctggccaa gtcctcgacc ttcctagagg
       61 tcgcctacct cctcatctat ggcgagctgc ccgatcgcga gtccttcgag cgcatggagc
      121 ggcgcatctc gcgccaccgc ctcctgcacg aggacttccg cgggttcttc acctccttcc
      181 cctcctcggg acacccgatg gcgatcctcc aggcggggat cgcgggcctg gccacctact
      241 acgaggacac cctcaatccg cacgacccct acgagcgcga gctcgccacg gtgctgctgc
      301 tggccaagct gccgacgatg atcagctaca tcgcccggcg cgccatcggc ctgccgctgc
      361 tctaccccga cccccagcgc tcctatgtcg aggacttcat ccgcctgacc ttcgggatgc
      421 cctaccagtc ctacgagatc gacccggccg tggtacgggc cctggacatg ctcctcatcc
      481 tgcacgccga ccacgagcag aactgctcga cctccaccgt gcgcctcgtg ggctcctccg
      541 acgccaacat gtacgcctcc gtggccgcgg gcgtgggcgc gctgtcaggc cccctgcacg
      601 gcggcgcgaa cgaggcggtc ctgcggatgc tggatacgat ccagagctcg gggatgagca
      661 cggccgagtt cgtccgcaag gtcaaggaca aggaggacgg cgtccggctc atgggcttcg
      721 gccatcgggt ctacaagaac tacgacccgc gcgccgcgat cgtcaaggag accgcccacg
      781 acgtcctgac ccgcctgggc tccgacgacg gcgaccgcaa gctcgagatc gccatggagc
      841 tggaggagac ggcgctgcgc gacgactact tcgtctcccg cagcctctac ccgaacgtcg
      901 acttctacac cggcctcatc taccaggcaa tgggcttccc cacgaagatg ttcacgcccc
      961 tgttcgccct cgggcgcctg ccgggctgga tcgcccagta ccgcgaaatg atcgccgatc
     1021 ccgccaaacg catcgggcgg ccccgccagg tctacgacgg ctccaccgag cgccactatg
     1081 tggccatgca ccgccgcaag cacgacgacg gccagtaccc ggacacccgc gccggcgtcc
     1141 ccagcctcga ccgcatcacc agggtctgaa tcacgagggt ctgaggctta cggctcacgc
     1201 cggtcgctca aggccgcggc ggtccagact ggggacgtac tttccccacg aggactgcgt
     1261 tctcccccaa accactgagg gcggacctca gtggtttggg ggagaagtac gtccccgacg
     1321 cagaagtacg tcgtcgatca gagcgttggg ccgtccggcg catggaggag cggctgatga
     1381 ccgccgagag ctcctgtggc cgtttgaggg aagcgcccgg gctacctgag gtagtcatcc
     1441 agggtggcca gtatcgtcgg ggtgacgcgt tcggccttct cgttgagaat caggtggtga
     1501 ccggcgggca actcgatcag ccgcttctgg ggcgccacta gtcgctcgta gaccaagcgg
     1561 ctgtaaccga gggtgaacag ggggtcgccc gtcgacacga acgccaccac cggacaggcg
     1621 atgctgccgt cgacgaggac cgacatatcg gtcgtgaaca ggctggatag gaagctcact
     1681 gggtaagcag tgcgtcccag gggatcccgg tagaactcgt cgcgccactc ccgctccgag
     1741 aagaccttgc tgacgtcgag gtagcaactc atcggtacct gaagcccggg cagcactcga
     1801 ccggcgaggg cgatgaccct ccggatcact gggtacgcca cgccgagcgc gttggggaag
     1861 cgtgtgaccg acagggactc tcgcaagggt gtgaacagaa cgttgtgcgg aaaggcggtc
     1921 cggatgcggt gctcgccgcc ggctgccagc agggtgagga ttccgccctg gctcgacccc
     1981 atcagcccga cggcgccggg gaaacgggcg caggcatagc ccaccgcgtc ccggacgttt
     2041 ccgatcatgt cgtcgagggt gaaccggtgg atgatccggg ggctgcgccc atgggacagc
     2101 gggtgaacgc cgactacgtg gtagccgtgc cggctgaccg cgtctaggaa ggggctgtag
     2161 aacagggggt gggtcatggt gcctgggacg aacacgactg tcggggccgc gtcctgctcc
     2221 gcctcccaga tggacagtgt gatgggggct cggcccgatt cgatcgagac ctccgagtaa
     2281 ctggccaggc cgatcgagtg ctcgttcagc agcgttgcga tgtccatgcc agctacgccc
     2341 tctcaaggtt gtcagcgttt ccggccggtc agcctgtgga cgctcacgcg acgaaggctc
     2401 gtacggctga gcggatgatc tcggcccgct ggtcggccgc agccaccagg ctatcgcctc
     2461 aacggcatgc tgaggccggt gggctacagc cgggtcaggt cgatcttgcc catctgcagg
     2521 atcttctcgc gcgtggcagc gtcagccatg agctcggcga tgttgtgggg gacgacctgc
     2581 caggacacgc cccagcggtc gacgcaccag ccgcagcgct cggcctcggg cacggccgac
     2641 agtcccgtcc agtagcggtc gatctcctcc tggtcccggc aggagacgat catggagacc
     2701 ccgggcgtga aggtgaagtc gtggaaggcc cccgagtcca tggccgccat ccaggtgccg
     2761 cgcagcgtga agtcggtgaa catgacggtc cccgcctcca tcggcccacc ctcctcgtag
     2821 cggcgcagag ccccgcggtg ggcgtcgtcg aacagggcga tccaggcctc agtggcctcc
     2881 tctgcgttgg cgtggttggt tccgccaaac atgaaggagg gcaggatgaa gggacgcggc
     2941 tcgccggccg ggtcggtgag catgagttgc caggtcatgc cgaagcggtc gcggacccag
     3001 gcgtagcgcg gcgagaaggg gtactcgccc agctccatga gcacaccgcc ggcggagagc
     3061 cgctcgtaga gctcatcgag gtaggtccgg gcctggtcct cgtcgccgaa caggagcggg
     3121 tcgaagttca ggatgcagct gatcgacggg ttcggggcgt actggtcgcc gccgttgatg
     3181 agcgagaggc ggaagccatg gatgctgacc gtggcagcga gcccaggtgt ctgctcgacg
     3241 acggagccct cgcggaagac gtctgcgtag aaccgggccg cttcgtcgtc ggcggcgtcg
     3301 caccagatgg cgggagtgat gagctgatcc atgcggacac cgtaccgcga ccgcacgtgc
     3361 gacggggtgc cgctcccttc cagccaggag cggcaccccg acaaggtgac agaagcgagg
     3421 gatcggtggg tcagtgcctg gtgacggcgc cggtcatgag atgaccctgc gccggtagtg
     3481 gagcactgct gcgccggtga gcatcccgat gaccgccagg gtcgtcagcc tgcccgctcg
     3541 gggtcccgta ttggacaagg acctgcgtga ggcggtggtg gtcggagcgg cagtgggcgc
     3601 tttggtgggc tcggggacaa cagccggtgt aggtaccgag ccgctatttg gatctggggt
     3661 gggttgaacg ctaggagcac cgccgtcggg cgggcaattc tcgccgacga cgcagacacc
     3721 gggcttgtcc tcagtgggga agccggggtc ggggtcgcat tcatcgccga cgccgtcatt
     3781 atcgaagtcg gactgacccc agttgtagac atcggggcag ttgtcctggt ctcgtggcgt
     3841 gctgtcgccg tcgtcggtga tgtcgacctg ggtggtggcg acggcagcct ggccgtcgga
     3901 ctgggtgacg cgcaggccga tgacgccgct gaattcctct gtgaaggtat gggtgatacg
     3961 cggcgagttg gcggtctcgt cgtagacgcc atcgccgttg aagtcccatt cgtaggaggt
     4021 cagggacccc gagaccgcgt gggaggccgc ggcatcgatg tcgacggaat ctcctacctt
     4081 ggcgacgtag ggaccctgga tccaggcgaa gggcttgttg agctcgctgt tgatggcgtt
     4141 gttgacgagg tcgctgacct gatcggggga ggaggcgtta gcggtggtgc cggagctgga
     4201 ggtgaccagg gttcggaact cggtggagct gagatgcccg gtgtcgatgc cgtagacgct
     4261 gaccggatcc acttcgtagg cagccttggc cacggaggcg gcggtatagc cggttcctgg
     4321 ttccgggtct cgaggtggtg cgtcgccgat gacgacgacg atcttcttca ccccgttacg
     4381 ccatttcata ttgacggcct gcatgacacc gctgtaaacg ctggcattgg tattaccaaa
     4441 atttcctccc tcatatgtta acgaatctag tcctttttct agggtaggac catcgctggt
     4501 aaagtcaaca tctgtccggg ctaaatagtt gttggcgttg aaatcagggt gatccttata
     4561 gtcgacgagc gcaaaacggt atgaagaagc gccttgctgt gtttgtttga tgattgtgct
     4621 gactctcgcc ctgagggcgc caacgttgtt cttcatggag ccggtggagt cgatggcgaa
     4681 gactatgtca atgtcgccct ttactcccag catcgggttg tcgaaactgg ggataccgac
     4741 cttcttggcg atgagttttg cgatctcgtc atggccgacg aggttcgggt ggtagaattc
     4801 atttgtgtcc caactgcttt tagactggat gttaccgttc tcgtctgttt gtccttcggt
     4861 ctcaaaaaat tcgttgatcc atcgatgtgg gttgcgatct ttcactgagg ggtctggttc
     4921 atggccgtca aatgtatcga tgactccgtc gatgtaagtg accttaaggc tagggtgtga
     4981 attattccat tcctggacga gagtcgattg tatttgcatg gaggagtcac taagtgatcg
     5041 cactccggcc cctgcattgt actcgacacc gtcatccttc aggatgtact ccctgttgga
     5101 agcgagacgc ggatacccta caaggataac ttgagcgtcg ttagttagtt tatcgtcgat
     5161 ttgttgaagt atggttaaag tgttggtctt aacgttctca agctgcgtgt tggcatttgt
     5221 gactttctcc ttgcatgttt tggcgtctcg cattccgaga gcgaagcact gttgcactat
     5281 gtcggagaaa ttgacgtcat tgccgccgat ggtgaacatc accagatttg tgtctgcaga
     5341 cattttgtca atttggttcg tcttcccgtc cgtatgtagg acgtccgacg taacactacc
     5401 gctgtaggcg agattttcaa gggtagtggg ggctccttgg tcattgagcc aacgcgtgta
     5461 tttgtgtgcc cagttattgt ggctgcgata ggattctttg gggccataat agtcgcccgc
     5521 tccatttccg gcagaatatg aatcgccgag cagtgtcgcg cgaatgaggt tgttggtttt
     5581 gacttcagcg gaagcaggcg ggctgagtgg caggctggtt gcgatgctaa ttagtgaaag
     5641 aagcgtgatg atggagcaga gtcgaagtag tgttgaaaag aaagaattgg agatgctaga
     5701 ggatttgatc ctgtacatga ctgcagcgtc ttccgtgttg ggtggtgctg agaatactcg
     5761 atgcgggtcg aaacggtgaa acggcggatt gacttattga agaagatcct ggatcactgc
     5821 gtttgtcggt tttgcgatct tgcggataac attaggcatg ctcatgaaaa atctaaagaa
     5881 actgctacag tattcagtcg ttcctttgga atgttcgaat cattctctgt gttggcggtc
     5941 agtgtcagtc gcatgtaatc atctccagct cggttgcggt gtcgagccag ccatacatta
     6001 gatgacgata tgtcggtctc ttcgacccat ccgttttttt ccgcatatct aatgaatgat
     6061 ttgtgaagag atgctatgtc accattttct ccttgaaacc atcgagttaa ggaaatatgt
     6121 ggatcttcga tcgagaacca ttcggtgggc ttggtctcct ctgtttcgat agccttatga
     6181 tcaaggatcg tttcggcgcc catggggtcg ttccgcagtg ctcgcagtaa ctttccatct
     6241 tctgtgaggg gtcctccggg gcgaaaagac cataatccgc cggcgaggag gagtcctccg
     6301 gtaaggctaa ggcatccgac tcttatcaga actcgtcgtc gagatgggcg cgaaggcggg
     6361 ccagtggatt ctgaagagga gttggaggta cgaggggagc cgtgagatcg cggggctggt
     6421 ggaggcatgt cacaattgta taaaaactaa catcgaagtg gcgagtatct tacatgctga
     6481 cgttcgtcag tgctagtgtt tgtctgatgt ctggtctctc catttcccgg ggcgtgttcc
     6541 ctgtatgtct cacatgtctg cggcagtcgc agtggcctgc attattttgc acgatttcat
     6601 gctgacagtg ttgttctcac gtcatttcac cgatcttagt ttacgtaaag gtgatttcta
     6661 actgtattgt agaacgcgaa gatgtcgccg tgcgtttcta ttgaaataca tttaaaaata
     6721 cggatgatcg gtaatctttg atctcgactc agtcgtgcca aaggtcggca gcatttaaat
     6781 ttcggaacgg atctgtgtca tgcgatccga tgtctgaatc gatgttgagg atcatgtcat
     6841 cgggcgtttc tgtgcctccg tgtcggccga tccaagggtc ggttgcggat ggtttgggat
     6901 ctttcgccca cctgtggctc cccgcatggt cgatgaagag tgccatgagt tcctcgggtg
     6961 acctgcttgc gtaagggggc aggtcctgtt ttcgagaacg tgggacaggg gcggggtgac
     7021 agggcagtcg tggtggaaga tggcgtcggc ggcgtgacct cgttggtgac gggattgagt
     7081 agacgacttc atcgtcaccg tgcgggttgt gccgcaccag catcaacacg tcagacccac
     7141 taaagaacag acaaccaccc atccattttg ccgacccctg cctgccgtac cctcaaacac
     7201 aaagagcccc ttatcttcca tgagtggggc gaagccggta ccggtttcgt tggcgcatgt
     7261 cggcgactgt tgtccacctt cgatgacgga gaatggccgt ttcagcgtgt cttccatttt
     7321 actggttgac ctcctctccg agttcgctta ggcggatcat cagtgcgctg gcggtactca
     7381 gtaggaatgc tgtgataccg atagcagtga agttgccggt gagagtgagc aacgggccac
     7441 cgataagccc tgctaccgtt gtaccgaggt acatcaccgc actagtgagg gtggagatgg
     7501 tgccgcgcgc tgtgctgtcg agttgctgca ggtggagcat acggacgctg agcattgcgc
     7561 ctccgcaggc gaagagaggt aggaatacca accccacaac gatcggaggt ggagagacgg
     7621 cgagggtcag gtaggcgatg cccatcactg tggcgctcag gtagatggct cggacagggg
     7681 tcatacggcc ggtcagccgg acgccgaaga gactgccgat cgtgttaccg atcccgccag
     7741 ccaggacgat gagcgccact gtgaccttcg aggtgcccag gccgtcctcc aaccacgtcg
     7801 gtgcgtaggt gaacacggta aagaacgcca gggtgtatgc gaggtaggac aggaatcgtg
     7861 tgaacgcttg tggtgcgtgg agcagggtca ggtacggcac cttcttagtt gccgcggtgg
     7921 ggcggatatc agggatctgg taccagagta tgactgttag ccccaacgag caggccccga
     7981 tgatggggaa gacaatgcgc cagtcgatga tcgcgagaag gctcccgagg ggaacgccga
     8041 cgacctgagc gattgacagt ccggcggtcg catatcccat gacgcgcaga acatgtttct
     8101 gatccgggcc gacgagtgcg ggaatcagtg cccacacttg tggtgcagcg atggccgccg
     8161 caccgccagt gataaaacgg aaggtgaaca tcgtccagaa accagcagaa actgcacagg
     8221 ctgctgttgc caatgcgaag acgaccatcc caagcgtaag gatgatccgg cgattacctc
     8281 ggtccgagat cggcccggat accagtccgg tgagcgcgta gccgatcgca tagacgctga
     8341 ccagccagcc gctctgcgtc gtcgacacgt cgaaagcctt ggctagcgat ggcaacagtg
     8401 gtgcgacgac gaaggtgtcc gaaccgatca ggaacatgac cgcgaacccg agtagtgaaa
     8461 gttttcggtc catagcattc tccagtccgt agagagtgcc tcaacgctaa accttgacaa
     8521 tgctgtcaat gtcaagagat gctgacgcgg tccattgaac tgtttgagga gagtcacgca
     8581 tgcgtatttc cgaggctgcc cggcgtgctg gcacgagccc gcggatgctg cgttactacg
     8641 aggctgaggg gctgctgacg cctacgcgcc gtgacaatgg ctatcgtggc tacggcgttg
     8701 aagaggttct agccgcccgc cagatcgtta cgctgtctca tgccggattc ccactttcac
     8761 tcatcaggac ggtgctgccc tgtgccacgg aaagcggtgc gttgagagcc tgcccctccg
     8821 ttgcacccga gctgcgccgc tggctccgcg acgtcgaaga acagattgag gtgctctcga
     8881 gcggcgccga ggtcatcagg agcttcctcg acaacctcca cgacgtcgca tctggctagc
     8941 tcaccttgta actgcgtggt ggcgtcgtac tcaacgaggg gcgtgccgag ttcggttgcc
     9001 gcgccgacgc tcaccccctg agcgtctggg ccttccaggt gccttgctgg cgtcatcgag
     9061 tcatcgacgt cggactctgc ccgccgtgga actactatgg ttaggctgac ctcatgagtg
     9121 agaagcctgc agactccacc acctccaccg acctgccgct gccctacgcc gaccgtcccg
     9181 ttgcctccgc ccctggtcac tgggtcctgg cccgtgccgg caagcgcgtc ctgcgccccg
     9241 gcggcgccgc cctgtccgcc gccatgctca gccacgccgg cctggcgggc gccgacgtcg
     9301 tcgaactcgc cccgggcctg gggcgcactg ccgccgagat catcaaggac cgccccgcct
     9361 cctacacggc catcgaccgc gaccccgacg ccgcccggcg cgtggccgcc gtcgtcgggg
     9421 atcttggctc cgtccgccag ggcgaggccg ccgacaccgg cctggacgac gccagtgccg
     9481 atgtcgtcgt cggtgaggcc atgctcacca tgcaggggga caagggcaag gccgctatcg
     9541 tcgccgaggc cgcccgcgtc ctgcgccccg gcgggcgcta cgccattcac gagctcggcg
     9601 tcacccccga tgacatcgac gaggagtact acaccgagct gcgccgcgac ctggcccgct
     9661 ccatccacgt caacgcccgc cccatgacgg ccgccgcctg gaaggagctc atggaggacg
     9721 ccgggctcgt cgtcgactgg gtcgacaccg cccccatggc cctgctcaag gtcgggcgca
     9781 acatccgcga cgaggggctg ggcggcttcc tgcggatcgc gcgcaacgtc gccgcggaca
     9841 aggagctgcg cgggcgcgtt caggagatgg cccgcacctt caagcgctac gagaagaaca
     9901 tggtcggcat cgccctcgtc gcccacaagc ccgagtcctg atccccgccc ctcccgcgag
     9961 ctccgggagc cggtcatcgg ccccgatggt gagggcggcg tcagtcgtcg cgggtggcgc
    10021 cgcgcagacc ggcgcgcagc acctcccggt tgagcaacgc gatcgcctcg atcgggatcc
    10081 ccgccgggca cgccggcacg cactcgccgt actccgagca cggtccgaag agctcatcga
    10141 gctcccgtgt catcgcccgg gcccggcgcc cccgctcgat gcgcccggcc ggcatgagcg
    10201 acaggtgcgc cagcttcgcc cctgcgaaga gcgccgccgc cccgttcggg catgccgcca
    10261 cgcaggcccc gcagccgatg caggcggcga agtccagtgc ccgctcggcc tgcagatgcc
    10321 cctgggcgac gtcgtcggcg tccggggcgg tccccgcggc cacgtccacg gttccgccca
    10381 cccggatgag ctcgtcgagc gccgtgcgat ccaccgccag gtcccggatg accgggaagg
    10441 ccgccgacct ccacggctcc aaccggaagt gcgtcacccc cgggaaggcc cgcaggtgct
    10501 gacggcaggc cggcgtcgtg tccatcggcc cgtgcggcac cccgttgacg aggaagccgc
    10561 aggccccgca caccccctcc cggcagtccg actcgaagac caccggctcg ccaccggcct
    10621 cgatgatctg gtcgttgagg cggtcgagca gctcgagcag actcatctgc ggctcggcgt
    10681 cctccaccac gtggctctcg aagaagcccc gcgcccgcgg cccgtcctgc cgccagatct
    10741 ccagctcgat cctcatcggt agtccctcac ttgcatgggt accagcgaga agctcagtgg
    10801 ctccgtgcgg cgcgtgtgcc cgccgtcggg ccccgtctgc caggccgaga cggagcacca
    10861 ggtctcgtca ttgcgctggg cctcgccgcc ctgggtcgcg tactcctcgc ggaagtgggc
    10921 gccggcggac tcgcgccggt ccagggcgtc gaggatcatg acctccgcca gctccaggaa
    10981 gtcggcgacc cgtagcgcct tctccagctc ctggttgagg cgcgcctggc cgccgaccac
    11041 cttgacatcg gcccagaact cctcgcgcag ggcgcgcacc tcctccagtg cgcgcagcag
    11101 ccccgcctcg gagcggctca ccccgcagcc tgcgtagagg acctcaccca gacggcggtg
    11161 gaaccacacg gggcggtggg ccccgcccac cgccatgagc gcctcaatgc gcttgcgggt
    11221 gtcggccacg gtctgaagcg cctccggcgc gtcgaggctc aggggcttgc tgcccactag
    11281 cctggccagg tagttcggca ccgccagcgg aagcacgaac catccgtcca cgctggcgct
    11341 cagcagcgag ttcgccccca ggcggttggc gccgtggtag ttgttcgagg cctccccgcc
    11401 cacgaacagc cccgggatgg tggacatctg atcgaagtcc gcccacagcc cgcccatggt
    11461 gaagtgggcg cccggggcga tgcgcatggg aacctcgtag gggtcctccc cggtggcgtc
    11521 gaggtacatc tcgaacaggt tgccgtagcg cgaggcgatg gtctccttgc ccagtcgctc
    11581 cagggcgtcg cggaagtcga ggtagaccga gttgcgcagc ggcccgacgc cgcggccgga
    11641 ctcgatctgc tcgcgggcgt tgcgcgaggc gacgtcgcgc ggggtgaggt tgccgaaggc
    11701 cgggtacttg cgctccaggt agtagtcgcg ctcgtcctcg gggatgtcgt tcgggggccg
    11761 ctcatccccg gggcgcacgg gcacccagat gcgcccgtcg ttgcgcaggg attcgctcat
    11821 gagcgtggtc ttggactgcc agtgggagct cacgggcagg gccgtggggt ggaactgcac
    11881 catgcaggcg gaggcgaagg ccgccccgcg ccggtgggcg cgccaggtgg cggtggcgtt
    11941 ggaggccatg gccagggtcg agtagtggta gacgctgccg tagccgccgg tggccagcac
    12001 gacggcgtga gcggtgtggg cccgcacttc gccggagagc aggtcccggg cgacgatgcc
    12061 ctgggcgcgg gagtcggcca cgatgaggtc gagcatctcg gtgcgggtgt gcatgtggac
    12121 gctgccggcg gcgatctgct cctggagcgc ctgggcgcag gcgatctcca actgctgacc
    12181 ggtctgtccg cgcgtgtagt aggtgcgcga gacctgcacc ccgccgaagg agcgggtggc
    12241 gagctggccg ccgtactcac gggcgaaggg cgccccgatc gcctccatgt ggtcgatgac
    12301 ccggccggac tccagcccca ggcgcacgac gtcggcctcc cgcccccggt agtccccgcc
    12361 cttgacggtg tccttgacga agcgcgtcag cgagtcgccg tcgaccttgc gggcccgggc
    12421 ggcgttgatc ccgccctgcg cggccaccga gtgggcgcgg cgcggggcgt cgtgcaggct
    12481 gaagcactcc acccggtagc ccaggcgccc caaggctgcg gccgccccgg caccggccag
    12541 gccggcgccc accacgatga cggtcagctt gcggcggttg gcgggattga ccaggcggta
    12601 ctcgtcgcgc cgacgctccc aggcctgctc gggcggacag tccggcagat gcgcatcaag
    12661 atcctcgccg atgtcgtaca ggccgccgac ggcccgcggt acgctcgcgc tcatccgatc
    12721 acccccgtgc agatgagtac cggcaacagg ccgttgacga ccgcgatggt cagggccacg
    12781 accagggcga cggcgcgaca cacctttcgc agcctggggc cggtgccgcc caggtcgatg
    12841 accacgttcc acaggccctg cgccagatgg agggagagcg ccagcatgac caggctgtag
    12901 aagaccgcca tgccggggcg cgacaggctc gccacgaggt tgtggtaggc gctgacctgc
    12961 atctcgccgt tcgacgtcgt cggcgcctgg aagctctcag gggcgatgag acggccgatg
    13021 gtcaggtcga gaatgtggat gaggacgaag accccgatga gggcgccggt caccagcatg
    13081 gagcgggcgc cgatggtgcg ggcgggcagg gctcggcgcc ggaaggctcc gcgagcgtcc
    13141 ctcgcacgtc gccacagcgc gatccccgcc gcgatgtgcg ccgcgatgca ggcccccagg
    13201 gccaggcgca tcgcccacag gagcccctcg tgcggcagga gcgggtaggc gacctgccgc
    13261 agccatgcgg cgtagccgtt gaacgcctcc ggtcctgcga gaactttgag attgccgacc
    13321 atatggacca cgacgaacag ggccatgatc gtgccggtga tcgccatcgt cgccttgagg
    13381 acgcgctgcg atgcccacac agggacgcgg cgcctgcgcc ggggcggcag tgcgtcacca
    13441 acgggctgag cagcctcggg ggtgcggacg gccgtggacg tcgcagccat ctggcctccc
    13501 ctcctttgcg cagaacaacc catgactatg ataacgaaca ccttgatact ggcatagagt
    13561 gtgaacacta tgtttcatag ggtcggcccg aaggcgggcc tgtcgcactc gcggcgctcc
    13621 cgcgggcgcg gcggccccag cctccgttat caaggcgaac cggccgcgcg ataacctcgc
    13681 ccaggaagta tgagctccat ggacgaaagg accagccgtg cccgttgagg tctcaccggt
    13741 cttaccgggc gcgccggtct cgccgcgcac ctccggaccc tcccgccgtc aggtcctgac
    13801 tggaggcgcc acaggtgccc tcgccgtcct cctggccgcc tccggctgct ccagaaaagc
    13861 cgacggtccg cgcctgctga caatcccgcg agaggacacg ggcaccttca tccgcaactt
    13921 caaccccttc accaccaaca gcgcccccat gaccgggcag gccatctacg agcccctcct
    13981 catcgtcaac cccctcagcg gcgaggtcac cccctggctc gccgactcct gggcgatgtc
    14041 cgacggcgcc accgctctca ccttctactt gcgccctggc gtcacctggt ccgacggcag
    14101 accgctggtg gccaaggacg tggtcaccac cttcgccgtc caccgcgccg tcaccggcgg
    14161 ctacgactac ctcgattccg tgaccgtcaa caacgccacc gcagtcaccc tcaccttcac
    14221 ccgcccctac tccgtcgccc tgcaggagct cggcagccag ctcatcgccc ccgaccacgt
    14281 gtggtccacc atctccgaac cggccgagta ccccaacccc gaacccgtcg ccaccggccc
    14341 cttcacccgg gtcgccaact tccaggccca gtccttcgac ctcatgccca accccaccta
    14401 ctggggcaac aaccgccagg acaacgccgg cgcctccagc accggccgca ccgccgacca
    14461 agactcgctc cccggcatcc gcatgctggc cttcgccggc aacgacagcg ccaatctggc
    14521 cgccgtcagc ggcgacgtcg actgggcgcc gcagtacatg gccgacatcc agaccgccta
    14581 catcgacaag gaccccgccc accgccatta ctggttcccc ggagccgact ccaccatcca
    14641 gtggaccctc aacaccacca aggcccccta caatgaccct gccttccgta aggccctcag
    14701 ccaggccatc gaccgcaaga ccatctgcgc caccggcatg tccggctaca cccagcccgc
    14761 cgaccccacc ggtttgagtg agagcttcca gacatggaag gacccggccg tggccgccgc
    14821 gcccctgtgc acctacgaca aggccgctgc caccgctgcc cttgacgccg ccggctacgt
    14881 cctcggggcg gactccaagc gcctgggcct ggacggcaag ccgctcaccc tgacgatcca
    14941 ggtgggctcg acgtcgtcgg actggctcag cgtcgcccgg atcatcgtcc agaacctcgc
    15001 cgacatcggc atcagcgcca ccgtcgactc atctgactgg accgaggtca ccgccgcact
    15061 ggagaccgga accttcgaga ccgccgtgtg ctggtcctcc ctgggcgcca ccccgtacac
    15121 ctactacgag gcgaccatga gcacccagaa ggtcaagccc atcggcaccc acgccctgga
    15181 gaactaccac cgcttcggcg acgagcaggc caccgccctg ctcagccagt tcgccgccac
    15241 caccgatcag gccggccaga tcgagatctg ccgccagatc cagcagcgct acgccgacca
    15301 gctgcccgtc atccccctgt tccccggtcc cgtctggggc gcctacaccg acgagcactt
    15361 caccggctgg cccaaccggg acaaccccta cgcctcactg agcacccgcg ccgccaccac
    15421 cgtcctggtc ctcaacgccc tcaggccccg cggctgatcc gccccgccgg cggccgcccc
    15481 acgccgcggg gctcgcgagg ctaccggcca cccggccgga acagggacac tatcccgggt
    15541 ggcggaccga gccgcccaca gcagcttgcc gctcgatgcc cgggaaggag gcacgcgccg
    15601 gtgacctaca tcctcaagcg cctgggctac tacctcctgg ccctctgggc ctcggtcacc
    15661 ctcaacttcc tcctgccccg gctcatgccc ggcgaccccg tctcacgcat gttcgcccgc
    15721 tccggcgccc gcctcaccga gacgcaggcc ctccagctgc gccggctgtt cgggctcgac
    15781 gacgcacccc tgtggcagca gtacctcaga tacctccgct ccgtcctcac cggggacctg
    15841 ggcgtatcca tctcccgctt cccggcaccg gtcagcgagg tcatcggcag ccagatcggc
    15901 tggaccgtcc tgctgggcgg tgtcgccctg gtcatcgcgg ccggcgtcgg cagcctgctg
    15961 ggaatcctgg cggcatggcg gcgcggggga gtggccgact cgatcctcgt gcccctcctg
    16021 gtcttcctcg gctccttccc ctacttctgg ctggccatgg gctccctcta ccttctcggg
    16081 atgggcctgg gctggttccc gctgagtcac gcctacaccg ccgggaccgt cgtggactgg
    16141 tccagccccg ccttcctggc cgacgtcgca cagcacctcg cactgccggc cctcaccatc
    16201 gtggcggtct ccctgggcgg ctgggccctg gggatgcgca acacgatgat cgccaccgcc
    16261 tcccaggact acatcctcct ggccgaggcc aaggggctct cgcgctcgcg gatcatgctg
    16321 cgctacgccg cccgcaacgc catgctgccc acggtgacca gcatcggcat gtcgttgggc
    16381 ttcatcgtcg gcggctcgat gctcaccgag gtcgtcttcg cctaccccgg catcggctac
    16441 cagctcttca gcgccgtggg cgccctggac tacccgctca tgcagggaat cttcctgacc
    16501 atcaccgccg ccgtcctggc cgcgaacctc ctggtggacc tcgtctacat ccgcctcgat
    16561 ccccgcgtgc gcgccagcgg gcagggggag tcatgagccc ggcccgacgg tacctccagc
    16621 agcgcacccg acggcgcgct caacggcgcg gcagcccctt gaccggcctg ctcgcctccc
    16681 tgacccgctc ccgccgggcc cggactgggg tggtgatcct ggccctgctc atcatcgccg
    16741 cgctcctggc gcccgtcatc agccccggcg accccgcccg catcacgggc gccccggccg
    16801 ctgccccgag cccggcccac tggttcggcg tgacgccgaa gggtcaggac gtgctcgcca
    16861 tgaccctgtg gggcgcccgc tcctcgctgg ccgtgggcct gggcgccgga ctcttggcga
    16921 cgctcgtggc cctcgtcgtc gccctggcct ccgcctacct gggaagggcg gtcgacggcc
    16981 tgctgtccgt ggtcaccaac gtcttcctcc tgctgccggg tctaccgctg ctcgtcgtcc
    17041 tggccgccta catgccgccg gggtggggca gcaccctcat cgtccttatc gtcacgggct
    17101 gggccggggc cgcccgcgtc ctgcgctccc aggccatgag cctgcgcggc acggacttcg
    17161 tggaggccgc cgtcgtcagc ggggaacggc cggcgcgaat catgatgggg gagatgctgc
    17221 ccaacatggc ctcggtcgtc atgtccacgc tgctgggctg cgtcaactcc gccatcggtg
    17281 cccaggccgg gctcgagttc ctgggactcg gccgttccga ctccgtgtcc tggggcacca
    17341 acctctactg ggccgccacc gacggcgcgc tcatgaccgg ccgctggtgg accttcgtgc
    17401 cctcgggcct cgccatcgcg ctggtcgcct acgctctggc cctcatcaac gccggcgtcg
    17461 acgaggccac caatcccggc ctgcgccgcg cggcctctgg ggcgcctagt aggcagcggc
    17521 ccccgactcc agctgccgag ccggacagtg gtaaccgggc cgtccctgaa cctgtcctac
    17581 gtatcgagga cctgagcgtc gagtacgacg ccggtgatcg ctctagcgga ggcggctgcg
    17641 tcatcggcgt cgaccggttc agcctcgccg tcgggcggga tgaggtgatg ggcctggccg
    17701 gtccctccgg ctgcggcaag accacggtcg cggccgcgat catgcgactg ctgggccccg
    17761 cggcgcgtat cacctccggc cgtgtcctgg tgggcgggcg cgatgtcctg gccctggagg
    17821 cgggcgagct gtgccgcctg cgctggcggg agatcgccat cgtcccccag gccgctatga
    17881 acgccctcaa ccccgtcatg acgatcggcg agcagatcgc cgacgtcctg accacccacg
    17941 atggcctacg acggcgcacc gcccgcgagc gcgccgccga gctgctggag tccgtcggca
    18001 tcccgtccgg ccgcctgcgc gcctatcccc atcagctctc tggcgggcag cgccagcgcg
    18061 tcgtcatcgc catggccctg accctcaggc cccgcctgct cgtcctggat gagccgacca
    18121 cggccctcga cgtcgtcgtc cagcgggaga tcatggaact ggtcctcgac ctcaaggccc
    18181 gcctgagctt ctccgtcctg ctcatcaccc acgacctgtc cctcatggcc ggggtgtgcg
    18241 accgcatcgg cgtcatggag gcgggccgcc tcgtggagga ggggccggct cgccgcatcc
    18301 tcacctcacc cgcccacccg gcgacgcagg cccttgtgtc ggggctgccg ccccgtcccg
    18361 gccgcaggac gaagacatcg gccgagccga ttcttgaggt cgagggactg cgcatggact
    18421 ttcccgccgg cgggctgctc tcgcgacgca ctatccgtgc cctggacggc gtcgacctga
    18481 ccctgcaccg cggagagatc ctggccctgg tggggcggac tggctcgggc aagtcgaccc
    18541 tggcccgcgt catcgcgcgt ctggagaccc ccaccgccgg gcgcctcctc ctggagggac
    18601 gcgacgtctt ggccgaggaa ccgcgccgcg cctcccgcag ctaccgcaga cgggtccaaa
    18661 tggtcttcca ggaccccttc gcctccctca acccggccca caccgtcggg catgcgctgg
    18721 ggcgggccct cgccgtgcac cggggcacca cggaacccgg ccgaggctcc gccgagctgc
    18781 tcgacgccgt cggcctggag cccgagctcc ttggggcgcg tccccatgag ctctccggtg
    18841 gacagcgcca gcgcgtggcc atcgcccggg ccctggcctg cgagcccgag gtgctagtag
    18901 ccgatgaacc cacctcgatg ctggacgccc cgctgcgcgc cggtgtcctc gacctgctac
    18961 tacggctgcg ccgggagcgg gacctgtcca tcctctacat cacccatgac ctggcctcgg
    19021 cccgctacct tgccgacacc acggtggtgc tccaggccgg ccgcctcgtg gagaccggcc
    19081 ccacggccga gctcatgaag caccccgtcc acccctgcac ccgactcctc ctgagcagtg
    19141 cgttggaaaa ccggcgtgaa gtctggggct atgacggtgc tccgggtgta tgagcatgat
    19201 gccggcggca gcgtgatgct gtgcttcggc ggcatcaagg agtccaagcg tctctggagc
    19261 atggttcctc aggggcgtcg aggactgact gcttatctct tgacggggat gtcggtgagg
    19321 cggaaggggt tgttggggct gggggtggag tgctgggcgg gttggaggtc gagggtgacg
    19381 gtgtcctgtc cggtgtcggg ccacaccact gtcagggtcg tggtgtcacc ggcacctagt
    19441 tggttgtcgg cggtgatctc gctgagcggg tggtgggttc cctctgcagc ggtgtagtcg
    19501 gccgggtagt agcgcgtctg agcggtcagc aggctcagcc ccgtcaccgc gctcgtcagc
    19561 ctgttgtcat cctcgccgcg ggcgcttccg agtatctggg ttggttgaag ccagtccgct
    19621 gggccggttt gagtgcctcc ggggcctccg gtggccttga cctcgccgac gaggtacttt
    19681 ccgcggcggg tgacctcggt gagcacgaag gtcaactcgt cctgtctccc atcccgtttg
    19741 accgtgaccc cctcgctgcc cttggcgacc ggtccctcgg ccttaggcag gtcgccactg
    19801 ccatgccccg tgcctttgct cgcgtcgggg ctcgacgtgg aggaggaggc ctgggtgggg
    19861 accagggtga tctccacacg gcggttgagc tggcggttgc cgtcggagtc gttgggaacc
    19921 cgcggtgtgc tctcgccctt accgtcagtg gacaccgaga aggccgacat gttggtcagc
    19981 tgccccagcc tgtcggagac ggacgtcgcc cgacgcttcg acaggtccag gttgtgggcg
    20041 tcatcggcga cgtcatcggt gtgccccacg atcgagacct cgccaccggg gtaggtggac
    20101 agctggtccg ccgccttctt caacgtggcg tccgcctggg cgctcaggtc ggccgagtcc
    20161 gagtcgaaca ggacgtcgga ggccagattg atgaccaccg acttgcccgt cacccgcgtg
    20221 tccgaggccc cgtccaccga ggcggtgaag gtctccaacg ccaccggatc agggctgctc
    20281 tcggtgtcgt agacgtcctc cagcgccttc ttggcctcct cggacagctt gccgtcgcgc
    20341 accacaggca cgccttcgaa caggccggac tcgggcacca ggacattgac ggtcgtggcg
    20401 tcgaccggct tgaacagggc gtgcaacgta gcatcgggct cctccttcgt cagctcagtg
    20461 ctctcggagg aggccttgaa agtctcctgt accgtaccgg cgtcgaagtc caccaaccgc
    20521 acgccatcgg caccagtgaa gtttcccgta ccgctccagg ccaggtgcac gtcgaacttc
    20581 ttgccgtcag acgacagacc gccggagccc atcttgtcca ggtgcacggc catgggcacc
    20641 accatgacgt cgtcggagac cgcagccggc cccaccgtga ccttcaaggt cgcccccaca
    20701 gtcgtcaccg tccgagttac cccctgaccc gaaccacctg aggcaccagc agagctcgag
    20761 ttcgagccgt ccgatgagcc gcctttcttc ctcctgtcca ggcaggcggc caggaccggc
    20821 acccccagga tcgaccagcc acccaccagc agcgcacgcc gagacacacg ccccaacacc
    20881 atcactccct ctccgcgcgc cacacagcat ccccaggccc tacccagcca cagaaacaca
    20941 gtcgaacaag atgatcatct catttaatca cgatttcata tagcgccatg ggagtattac
    21001 cgatcccctg agtatcgact ggaccagggg ctcgtgcctt cggaagaggc tctcagtggt
    21061 gtcagacgtg cagacgggga ggctccggct cagcggctca ctggttggct tgcagtggcg
    21121 aggtcagctc gatgcccttg ccgccgcggg ccagcgcctc gacggcaccg gactgggagt
    21181 tgcggcggaa caggacgttg gaggcaccgg ccaattcgcg ggccgagacc acgcgcggct
    21241 ccttgaacag gccgtggctg ccgggcacca cgccgccctg cggcatgagg gagactttcg
    21301 tcccggccgt caggtacagc ccagcctcga cgacgcagtc gtcacccagc gggatcccca
    21361 gccccgagtt cgcgcccagc aggcagcgct cgcccagggc tacgcgctgg cggccgccgc
    21421 ccgagagcat gcccatggtg gaggcgccgc cgccgacgtc ggagccgtca ccgatgatga
    21481 cgccctggga gatgcggccc tcgaccatgg agcggcccag cgtcccggcg ttgtagttga
    21541 cgaagccggc gtgcatgacc gtggtgccct cggacaggta ggcgcccagg cgcacgttcg
    21601 aggcattgcc gatgcgcacg cccgagggta ggacgtagtc ggtcatgcgg gggaacttgt
    21661 ccaccgagtg gacctgtacc gggcgcccca gagcggcgcg caggcgggtg cgggtggtct
    21721 cgaagtcctc ggcgcggcag gggccggcgg aggtccacac cacgttgggc aggcgggaaa
    21781 agatcccatc caggttgacg gtgttgggct tggtcaggcg gtgggacaga gcgtgcaggc
    21841 gcaggtaggc gccggccacc gtctgggggg cgtcgtcgag atcggcccag gtgcgcacca
    21901 cggtggtgtg tacgccgcgg gcctcatcgc ggcgctccat ggcgctcagg gtcgacagga
    21961 ggtcggcatg gccgtcctcg ggctcatcgc cgagaaccgg gcgggggtac cacacgtcaa
    22021 gggtgttgcc gtcgtcggtt acggtcgcca gaccgagacc ccaggcactg cgagtcgtca
    22081 tggggaacac cctacgggac ccggtggctg accgaggtgg acgggcgtgc gagaatcacc
    22141 gcatggcgcg cacgacgatc cacctcatgc ggcacggcga ggtgcacaac cccgagggcc
    22201 tcctctacgg ccgcctgccc ggctaccacc tgtcgaccct gggccaccag atggcccagc
    22261 aggtcgccga tgtcctgtcc gcctccgggc acgacatcac ccgggtcatc acctcgcccc
    22321 tggagcgggc ccgcgagtcc ggagcgccca cggccgcggc cttcggcctg acgccgacga
    22381 cggacgcccg gctcatcgag gcgggcaacc gcttcgaggg cgtggccgtc aaccgcaacc
    22441 gctggatcct ggcccacccc gccaactgga gcaactacgt caacccgctg cgcccctcct
    22501 ggggcgagcc ctaccgcgag atcgtcgaac gcatgcgcgg cgccgtcgtc tccgcgctgg
    22561 gcatcgccga gggccacgag gctcttctcg tctcccatca gctgcccgtc tggtcgctgc
    22621 gcctcttcct ggaaggacgc tctctggccc atgacccgcg ccggcgccag tgcgccctgg
    22681 cctccctgac ctcgctgacc ttcgaggacc gcaccctggt ggggctggcc tactgggagc
    22741 cggccggaga cctgctgcgc caggcccgcg atatggtgcc cggcacctcc gccgcccggg
    22801 ccgccaccgg ccggcccctc cacaccgaca gcgacaacag cgacaacagt gccaacagca
    22861 ccgaggcggc gcggtgaccc agcagccgcc ctcgcgccct gtcggcggcc aggtcgtgcg
    22921 caccggcaac cggtctgccg catccggcga ggtgacgcgc accggggccc ggcggccctc
    22981 cccgaggcgc ccctggaccg ggcaggactt cgtgtggtgg cacaccgccg ccgtcctgac
    23041 cgccacccga cagggccggc aacccaaccc ggtctcaccg gccatcgacc ccgtgcgccc
    23101 ggccctggga tccggtgagg tcatgctggc cacctgcgac gccgagctgc tcatgtggcg
    23161 gcgcggggac gccgcctaca acccctcccg cggcttcttc cttgccggcg gccccgtcgg
    23221 cctggccctg acagccgcct tcttcggcgg acaggcctac ctcaaccacc ggcgccgccg
    23281 cgccgccgag gccgatgccg ttgagaagtg gcgccacctg gccgccgccc gcctgaccgt
    23341 ctccacccac ggcatctacc tgggtacggg ggagggcgtc atgcccatct cctacgccga
    23401 catccaggag gtccggctca ccgccaccgg ggagatcgtc atcgccgccg ccaacgcctc
    23461 cggctcggtg cgcctgaaga tccgggccca
//
