LOCUS       NZ_CP066060.1          23533 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP066060.1 Actinomyces oris strain FDAARGOS_1051 chromosome,
            complete genome.
ACCESSION   NZ_CP066060
VERSION     NZ_CP066060.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:59:48
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1993634
            Orig. end    :: 2017167
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23533
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2003634:2007167]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13533
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..23533
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23533
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="9"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             222..1493
                     /locus_tag="ctg1_1636"
                     /transl_table=11
                     /translation="MAENHVALLLTPEGWELLSSLPPYDPSEALSLGRSLREEGHSPAL
                     VAAALTQQRLRERATAKFGPFAQQMLFTADGLEQATRLTVSAHHAARYAAAGVTKVADL
                     GCGIGGDAVALAGLDLPVLAVDRDEAAAALATINLMPFPHASVECADALEIDLVERGVD
                     AVFADPARRTEGRRITDPEQWSPALSQVLALRETVPALGVKVAPGIDHAALPSDAHTQW
                     VSVDGDVVEAAIWCGPLAPEGPGRSALILRSGAQNATACTLVDPSTSDPSQPPVQVDPI
                     NSPDDLGSIIHVPDGAAVRAGLIAHLCETLDARPVGPRIGYLTGERLPDEATAPFVRSF
                     RLTEVLPLRLKTLRSRGRELGIGRLEILKRGVDVSPDALRASLRLSGQESETWILTRLG
                     DKAKGAVLVVEPITSASSAHSPTS"
     CDS             1570..2802
                     /locus_tag="ctg1_1637"
                     /transl_table=11
                     /translation="MQNTTDTTSPNAASADAQLPPARRPQSLDFAGSARSTLGVEWELA
                     LIDRDSLDLRQCAEEILQKVGPDPHVHGEMMLNTIELVSGARRTVAECMEDIAFAFDRV
                     LPVTDPLRVDLASAGTHPFADPLVQKVTNAERYARLVDRTRLWGHQMLIFGTHVHVGVE
                     DRSKVLPILKALLTRTAHLQCLSASSPFWAGADTGYADNRAMMFQQLPTAGAPEQFSTW
                     EQLESYTGDLVHTGVIEDFTEIRWDVRPSPRLGTIEVRACDAATNLTELAGMAALTQCL
                     VESFSRTLDRGEELDALPDWYVAENKWRSARYGMDAILIVNSAGEEELVGDTVERMLTE
                     LAPVAEDLGCAAELDSVRTTLETGASYQRQIAAVRAYGGQREAAVRLLLAEARAGRPLR
                     PTEVLSLAAKS"
     CDS             complement(3531..7415)
                     /locus_tag="ctg1_1638"
                     /transl_table=11
                     /translation="MSTRTQSSAPGASPYPSPAPSSPPSAGAAAPDDAAEPPPQGNAQR
                     SREGQAAIARLGAPVRTRLRIGQALVLLSAVLSVAPYIALVQLGDILLRAHRTGLSPDP
                     QQVSGVVMVLVSAYSTRLLLYFLALLITHLADLSLRDRLRRDIVARISHAPLSWFTAST
                     SGRLRKAVQDDTTLVHTVIAHGPVERLNAIVTPLALLGCAFWIDWRLALLAVSALVLYV
                     LTYSVSMRGMNEKTVEMDRKLAAISSAMVEFVSGIGVVKAFGRVGRAHSAYLTAADEFS
                     AFYRAWAMPLVTVTCLSFTWVSIPVLLLVNLGGGALLIHAGAVTLPQVLATTLVALVLP
                     AALITIASISWSYQLAGAAALRLCEVLDTPVLPAADRPAQPRAERVEIDHVSFSYGEVL
                     AVDDACLTLEPGTVTALLGPSGSGKSTLATLIARFADPDAGAVRIGGVDLRDMDESTLY
                     STVSFVLQDAQLLATTVRENIALGRPEADLAQVRAAARVARIHEEIMALPQGYDTVLGQ
                     DTALSGGQEQRIAIARAILLNTPVIVLDEATAMADPESEAEIQQALSALVKDRTVLVIA
                     HRPAAVRGADRIAVMDGGRIVAAGTHDDLADEPHYRALLRQAGEIEGATEVDGDETATR
                     TEDPALADGAADSPDDGVADSVADGAADSPDDGVADSVADGRVLATSPSRVDDRDGRTG
                     ATRPVPSTPGGSSRPANSLLSRFRRLMTDSSWRQTRGCIALAGVNGVLVGLALLVLLPA
                     SVALATGAPRWGLSFGGWLVVLVVLGLGAAVCDFQGRRLGMSGALGFMHDVHHAVGDRI
                     ARLPLRWFTADSAGTLSRAVSQEMVALGESAAHFMYLLTSTAAACVVVGVGSWAWDWRL
                     GLLLTLAAPLFAGFVRLSRRLLDRGKSISEPAERELASRIVEIARCQGALRSCRAASGY
                     SRLTAAFDDGARASRHALWWESAGNLVNGALSQIVVVAMIVLTSSLAASGAMEPLVAIA
                     VIGMCLRFTTMLDDIGAAVMGVEERRQMMNHLDAVMDAELMAEPKVPSSLPEPGVVELD
                     DVVFGYRPDAPVLTGVSMKVPARTMCAIVGPSGSGKTTIARLVARFWDVDSGTVRVGGT
                     DVRDMPTSQLMEQLSMVFQDVYLFDDTLAANIRIGNPAADDAQVRWAADLAGVTEIVDR
                     LPHGWDTRVGEGGRALSGGERQRVSIARALLKRAPIVLLDEATSALDAENEANIVAAMQ
                     ELRRTSTLIVIAHKLETIAAADQVIVLDDAGRIAQRGHHNELVSVEGPYRSFWEQRTRA
                     RGWALVSRQK"
     CDS             7536..8258
                     /locus_tag="ctg1_1639"
                     /transl_table=11
                     /translation="MTRSARLGRPTGPRPGFSRDDVVDAALEIGIAEFTLTAVAKHLGV
                     AVSGLYRTISSREDLLAACLERIAAEVETPGAGRRWPDAVRAHAEAIWAMLERYPGLAG
                     VIMGVPWAHQLFATPVAQACQVLVDGGLGVEEAGVVLDFVGDTVISTHAQIEVMRSPAA
                     PSGLGGPTGLEETSRFAAAAGNPPLPEALTPNESWLERGGLDRKIEIIIRGVAAGLPPS
                     AADTGGKSASGGDVSGRR"
     CDS             complement(8242..9288)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1640"
                     /sec_met_domain="Peptidase_M22 (E-value: 5.2e-86, bitscore:
                     286.0, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSDPLILGIESTCDETGVALVRGRELLADVTATSMDQYARFGGII
                     PEIASRAHLESFLPTLDAALEKAGVDLSEVDTVAVCAGPGLIGSLTVGISAAKALAASL
                     NRPIYGVNHVIGHLAVDELVDGPLPERFVGLIVSGGHSNLLSIRNVATDVVELGGTLDD
                     AAGEAFDKVGRLLGLPYPGGPHVDRLSQEGDRGAIRFPRGLAAGKDKERYRYDFSFSGL
                     KTAVARYVESLEDSGQEVPSADVCAAFSEAVNDSLTAKAVRACLDTGCDTLVVGGGYSA
                     NSRLRSLAAERCEEAGITLRLPPLRFCTDNGAQIAALGSAAVRAGVAPSPMDFAPDSGM
                     PLDVSVAH"
     CDS             9361..9990
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1641"
                     /sec_met_domain="HAD_2 (E-value: 4.5e-12, bitscore: 43.7,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VAALIDAGVPLALVTSAPIELMRVRMEDAGVPIPPVVVSAGDVER
                     GKPDPDPYLKAAELLGVPISSCLVLEDAPSGYTSARRAGAQVLLVGDGVPEAGSHVPRI
                     ADFTGITFTIHERRAGHVLRAGTFHAAGRVSFRAGPFDAVGDSNPVTVRATCPRPEESA
                     PARAESPHRRALVKGMHVEHHRAGHFSRPPTECLEDDARSARLGME"
     CDS             complement(10001..10771)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1642"
                     /sec_met_domain="Fer4 (E-value: 3.8e-06, bitscore: 23.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1e-06, bitscore: 25.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 3.3e-25, bitscore: 85.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.6e-11, bitscore: 41.1,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.4e-05, bitscore: 22.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNIKLKIWRQKNKDSKGHFEEYAMSGIEEHMSFLEVLDLLNEQLF
                     AEGKEPVAFDSDCREGICGQCGVVINGQAHGPIRSTTCQLHMRHLAEDPSFKDGSTITI
                     EPWRSTGFPVLRDLIVDRSALDRIVQAGGYISVNTGGAPEAHSVPVQKEKADAAFEAAA
                     CIGCGACVAACPNASAMLFTGAKISHLGLLPQGQPERLARVVSMLNQHDAEGFGGCTNI
                     GECAAVCPKSVPLEVISRLNRDLGHALWKGQHAH"
     CDS             complement(10768..12768)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.2; E-value:
                     1.4e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1643"
                     /sec_met_domain="FAD_binding_2 (E-value: 5.7e-58, bitscore:
                     194.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 7.3e-34,
                     bitscore: 113.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELIDGLYYEGEKIADTKAPHSVPIDRRWEQRKFEAKLVNPANR
                     RKLDIIVVGSGLAGGAAAASLGEQGYNVKVFFYQDSARRAHSIAAQGGINAAKNYRNDG
                     DSVYRLFYDTVKGGDYRAREDNVYRLAEVSANIIDQCVAQGVPFAREYGGLLDNRSFGG
                     VQVSRTFYARGQTGQQLLIGAYQALERQVHAGTVKEFRRHEMVELIIVDGRARGIVTRD
                     MVSGKIETHLADAVVLASGGYGNVFFLSTNAMGCNATAVWRAHRKGAYFANPCYTQIHP
                     TCIPQSGDFQSKLTLMSESLRNDGRIWVPKKAEDCDKDPRDIPEEARDYYLERIYPAFG
                     NLVPRDIASRQAKNMCDEGRGVGPAIKERDANGNERMMRRGVYLDFSEAINRLGKDAVS
                     ARYGNLFEMYQRITGDDPYEVPMRIYPAVHYTMGGLWVDYDLESNVPGLYIAGEANFSD
                     HGANRLGASALMQGLADGYFVLPDTMNNYLADMLRLGKVDPNAPEIAEAKRSVEERVAR
                     LMALRGTRSVDDFHMALGRIMWEYCGMERRDAGLRDAIGQIRALKEEFWRDARITGQAD
                     ELNQALEKAGRLLDFFELAELMCIDALHRRESCGGHFRAESQTPEGEALRHDDEFLYVA
                     AWEWGGENQPPILHKEDLVYKDIELKQRSYK"
     CDS             complement(12781..13533)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1644"
                     /sec_met_domain="SucD_FumR (E-value: 3e-08, bitscore: 30.7,
                     seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRMMAISGLVFLFFVLFHAYGNLHYFEGEVAYDHYAVFLRALLV
                     PIMPYGGVLWILRLALIACLLAHAGSAFHLWARNKRARGNDKYAVKKPGAEYFASRYAM
                     RTMRWGGVILLLFIIWHILQYTTLSLTPGGHYVHGRAYLNMYYGFQLWWVWLIYAVALA
                     ALCLHVWHGVWSALQTLGAVRGNTIPFIRLIAFVLAFALFAAFMAVPTAILFGYVDAPM
                     ATGDYYPQFCDAIGSSAEHFAECATATH"
     CDS             complement(13922..14527)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1645"
                     /sec_met_domain="Acetyltransf_1 (E-value: 7.4e-13,
                     bitscore: 46.1, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VPEATGAGRAPGLREMAAGDLEAVARLEGELFGAEAWSRDLLAAE
                     LEASHGPMADRRYVVVESEESDGDGDAYDAADRAVGTGSHGPRLLGYAGLYHAGGLTSA
                     DLLTIATIPAARGRGIASLMLTELVSTAREVSCPDVLLEVRQSNETAQRLYTRHGFVPI
                     GRRRRYYQAPPEDAVVMRLTLRPRPGPVGAEAGEPGEA"
     CDS             complement(14553..15311)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1646"
                     /sec_met_domain="Peptidase_M22 (E-value: 1.6e-17, bitscore:
                     61.4, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRILSIDSSLGTQLAVVDAAPSAAGARALQVLSQDEQADTRRHAE
                     SLGQMLSRALSAPEAAERPLDAVVAATGPAPFTGLRAGLVTAGVVGRTRGVPVHGVSSL
                     DAVARRALDELGAQEGQTGPVVLVATDARRREVYTALFRANGPDDVTRLTEIIVCSPAQ
                     VAQRLAEQAPGPGGGSGDIDVVAGSGASLYPELAEMASCQKALAPVSGDALTQVRIALA
                     RLERGEQLSTQPLYLRHADVQMPAARKRVR"
     CDS             complement(15321..16370)
                     /locus_tag="ctg1_1647"
                     /transl_table=11
                     /translation="VNTPTTVAPVRNAIPIRAAQRSRRPRRLLLPAAAATLLGVCLLTP
                     GPARAVADTGPRPVPITSAGGVAGVPADADSRDEAKTLMESECVAQVRQSTGEQGEITV
                     GDPRSVYTWASGFLDGSQPSAQPVDTGDWAATVSSGGKSVGLLEVVHDKGHATCTPVFD
                     DDLATDVDQMGEAHLVHDRNANAWYSLNGTTVTAMGEAATRRLAGPIELRDYGEILRER
                     AGSKPKTSAGQSEERSTTGGWAIWGPVLAVVVVGIITVIITVRHERKVTAPLRQARNRA
                     DMAERADRLSRDESDTQGAAVRRGIPRAAIDLSLLGDGADDDADATAGETLGDTIPESR
                     VNLPRDPRA"
     CDS             complement(16367..17005)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TsaE"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1648"
                     /sec_met_domain="TsaE (E-value: 5.2e-31, bitscore: 104.5,
                     seeds: 801, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPAPHTPQTAPGITVATGDADETRALGARLARLLRAGDLVMLSG
                     GLGAGKTTLAQGIGAALEVRGRVSSPTFIIARVHPALSDGPDLIHVDAYRITSLEEIDA
                     LDLDSSLERAVTLVEWGEEKVEALSPDRLEIQVLRPHGAVRAEHPQPEDAPAGAESPAG
                     SVAGEPVVDLGEVDDGNRTIIVRAVGPRWADVDLSPLAADASCQPGAPL"
     CDS             complement(17086..18402)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ala_racemase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1649"
                     /sec_met_domain="Ala_racemase_N (E-value: 1.4e-55,
                     bitscore: 185.5, seeds: 314, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPSTAPRPAVAQCARPPAATTSRAVVDLAAVAHNGRRLAQVAGV
                     PWMAVVKADAYGHGLGPVALTALSAGASWLGVAQLAEALTLRALLDEAGVSRPAGESAS
                     QAPRLLTWLLPVMEPDRAAAEDSPLRAALAADLDLSVSTLPQLEALSAAARAQGRVARL
                     HLKVDTGMSRGGATVEELPALAAALRRAEDEGTVDVVGLWSHLSRADEPASGSTEEHLE
                     RYRQAEQVVLAAGLNPPTHHLAATGGLLWHPQARMDLVRAGIGLYGLSPDPSVATGAEL
                     GLRPAMRLESPLVQVKRIEAGQAVSYGGTWSAPTDRWVGLVPLGYSDGIPRAASSAGPV
                     GVGSLMTSIVGRVCMDQVVIDLGPAVDETGAPLPAPARVGETAVLWGAPEVSDQEAVPT
                     ADEWAQACGTINYEIVTRLGARVPRCYIGEPGTGDYSRP"
     CDS             complement(18524..20443)
                     /locus_tag="ctg1_1650"
                     /transl_table=11
                     /translation="MGRMSDLNDLPRSHDVTDPTTCAWPAQEIAAAEAPVTAGTDRYMR
                     AAAHAVARAALRELRQGAGTAGTAVAPARPVPAPLTSMSPMGAAATPASPLSPATPLGG
                     TGEAAGMQTGLGWISGAPVLLLVGGGHNGADTLLAGGLLAHSGCAVSAVLATEHPHPVA
                     LEEARGHGVTIHGAGYRSDDGTGQDSAEAMTAIEAFLVHGGLVLDGLTGIGATGALRPD
                     AAALIAPLIAAGEPGRRPLRVIAVDLPSGTGVDDGTVSGPVLAADHTVTFTCLKGCQCL
                     PPARHLCGVVEVVPLGLPAPTSRPLARRPVDGALGDYLTRAVGEPGPGDHKYTRGVVGL
                     WAGSESYPGAAVLAASGAVRAGAGMVRLSAPRRVEDLVLAARPEVVPAAGRVQALVLGP
                     GIDPADATRADEVRTVLASTLGPCGKDRQCPTRVPTVVDAGALSILPELLTEDLSCTPL
                     HVLTPHAGEAAALLIALEDQGTPAQETCRWSRERVEAHPGLAARELCRRTGATVLLKGA
                     TTLIAAPQRPLVSVDGGPGWMASAGSGDVLAGILGAVLAGAAARWEQGAPDASGADLVL
                     DALVDSVAAGVRLHALAGAYAAASPQGAGGAGTGGHPIAALDIAVALGPARLELNWLQA
                     VPHA"
     misc_feature    complement(20066..20068)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             20632..21111
                     /locus_tag="ctg1_1651"
                     /transl_table=11
                     /translation="VIRAVGTDLVDIPRLEGYMDRVPGLRERLFTPAELAACQKRAASL
                     GARLAAKEAVLKALGSAYAELGLDAPQGWEYQDIEVTSTPGTPPRLRLTGAAAMAARQA
                     GIGHWHISLAHDGGMAQAFVVAQADHVDNDDDLTLSSQRSQARTKQQIRSPRPAL"
     CDS             complement(21193..23097)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SIS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1652"
                     /sec_met_domain="SIS (E-value: 9.6e-33, bitscore: 110.1,
                     seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGHVGPLSETGSSRSLTVLMDGLGRLEYRGYDSAGVALVGP
                     SGLDVIKEAGKLSGLRAILEATPPAPATAGIGHTRWATHGGPTTANAHPHRAGHLAVVH
                     NGIIENFRPLREEVEAAGRELVSDTDTEVVAHVLDIDFTSRLRQDPSAASDPTRVADLL
                     VASMQAVTARLEGAFALLAVTDLAPAAIVAARRSSPLVIGLGEGENFLGSDVAAFVAFT
                     KKAAEVDDDQVLLLTADAVHVWDKDGNAVEPKAWEVSWDASAAVKGGYDTFMDKEIHEQ
                     PTAVADTLRGRVDERGELQLDEMRIDPAVLRSVDKIIVIACGTAAYAGHVAKYAIEHWC
                     RIPVEVELAHEFRYRDPVVSEKTLTVAISQSGETMDTIQAVRHAREQGSKVLAIVNTYG
                     STIAREADAVLYTHAGPEVAVASTKAFLAQITACYLLGLYLAQLRGNKWPDEVAEYLDN
                     LAAMPDRIQHVLDHEEARVRELGSELADKSSFLFLGRHVGFPVALEGALKLKELAYVHA
                     EGFAAGELKHGPIALIEEGLPVFVIVPTPRRPVLHDKVISNIQEIRARGARTIVIAEEG
                     DTDVEPFADHIIRMPVTPTILWPLLTVVPLQIFAAALAGAKGLDIDQPRNLAKSVTVE"
ORIGIN
        1 ggttccccct cagtcatcag tccccacccg tcttcccgtc cagcgccttt tcggccccgc
       61 cggtgcgcgg cgcctcggca cacaacccta ctcaccgccg gccaggcagg gccccagggc
      121 cttctcagat ctcctcccgg cctccctgcg tgggcccctt cccgctccac ccagtgaaca
      181 tcacgcccat tggcaggttc tgcatggaat gatcgggggt gatggctgag aaccacgtcg
      241 cgctcctgct gacccccgag ggctgggagc ttctgtcctc cctgcccccc tacgacccct
      301 ccgaggccct gtccctgggt cgttctctgc gcgaggaggg acactccccc gccctggtgg
      361 cggccgcgct gacgcagcag cgcctgcgcg agcgggccac ggcgaagttc ggccccttcg
      421 cccagcagat gctcttcacc gccgacggcc tggagcaggc cacccgcctg acggtctcgg
      481 cccaccatgc ggcccgttac gcggccgcgg gcgtgacgaa ggtcgcggac ctgggttgcg
      541 ggatcggggg cgacgccgtc gccctggccg ggctcgacct gccggtactc gccgtggacc
      601 gagatgaggc cgcagccgcc ctggccacca tcaacctcat gcccttcccc cacgcgagcg
      661 tcgagtgcgc cgacgccctg gagatcgacc tggtcgagcg aggggtggac gccgtcttcg
      721 ccgaccccgc acgccgcacc gagggacgtc gcatcaccga tccggagcag tggtccccgg
      781 ccctgtcgca ggtgctcgca ctgcgcgaga ccgtgcccgc cctgggcgtc aaggtcgccc
      841 ccggcatcga ccacgccgcg ctgccatcgg acgcccacac ccagtgggtg agcgtggacg
      901 gcgacgtcgt cgaagcggcc atctggtgcg gaccgctggc gccggagggc cccgggcgct
      961 ccgcactgat cctgcgctca ggagcgcaga acgcaaccgc ctgcacactg gttgatccga
     1021 gcacctccga cccctcgcag ccgccggtcc aggtcgatcc gatcaactcg cccgacgacc
     1081 tgggcagcat catccacgtt cccgacggcg ccgccgtgcg cgccggactc atcgcccacc
     1141 tgtgcgagac cctggacgcc aggccagtgg gaccccggat cggctacctc acgggcgagc
     1201 gcctgcccga tgaggcgact gcccccttcg tacgctcctt ccgactcacc gaggtcctgc
     1261 cgctacggct caagaccctg cgctcccgtg ggcgcgagct gggcatcggg cgcctggaga
     1321 tcctcaagcg cggagtcgac gtctcccccg acgccctgcg cgcctcactg aggctcagcg
     1381 gccaagaatc ggagacctgg atcctgaccc ggttgggaga caaggcgaag ggcgccgtcc
     1441 tcgtcgtcga accgatcacc agcgcctcat cagctcactc accgacgtca tagaccccca
     1501 ttattcccgc gacgacagac ccccggtcag cacccgcgag ggaaccgggg aacccgagga
     1561 ggccaggaca tgcagaacac gactgacacg acgagcccga acgccgcgtc cgccgacgct
     1621 caactgccgc cggcccgccg cccccagtcc cttgacttcg ccggatcggc ccgctccacg
     1681 ctgggggtgg agtgggagct ggccctcatc gaccgagaca gcctcgacct gcgtcagtgc
     1741 gccgaggaga tcctccagaa ggtgggcccg gacccgcacg tgcacggcga gatgatgctc
     1801 aacaccatcg agctggtctc cggggcgcgc aggaccgtgg ccgagtgcat ggaggacatc
     1861 gccttcgcct tcgaccgagt ccttcccgtc accgacccgc tgcgcgtgga cctggcctcg
     1921 gccgggaccc accccttcgc cgacccgctg gtgcagaagg tgaccaacgc cgagcgctac
     1981 gcacgcctgg tggaccgcac ccggctgtgg ggccaccaga tgctcatctt cggcacccac
     2041 gtgcacgtcg gcgtcgagga ccggagcaag gtcctgccga tcctcaaggc cctgctcacg
     2101 cgtaccgccc acctgcagtg cctgagcgcc tcctcgccct tctgggcggg ggcggacact
     2161 ggctacgcgg acaaccgcgc catgatgttc cagcagctgc ccaccgccgg cgcccccgag
     2221 cagttcagca cctgggagca gctggagagc tacaccgggg acctggtcca caccggcgtc
     2281 atcgaggact tcaccgagat ccgttgggac gtgcgcccct caccgcgcct gggaaccatc
     2341 gaggtgcggg cctgcgacgc cgccacgaac ctgaccgagc tggccggcat ggcggcactg
     2401 acccagtgcc tcgtggagtc cttctcccgc accctggacc ggggtgagga gctcgatgcg
     2461 ctgccggact ggtacgtcgc cgagaacaag tggcgctcag cccgctacgg catggacgcg
     2521 atcctcatcg tcaactccgc cggtgaggag gagctggtgg gagacacggt tgagcggatg
     2581 ctcaccgagc tcgctcccgt cgccgaggat ctcggttgcg ccgccgaact ggactccgtg
     2641 cgcaccacgt tggagacggg ggcctcctac cagcgtcaga tcgccgccgt cagggcctac
     2701 ggagggcagc gggaggcggc cgtcaggctg ctgctggccg aggcccgcgc gggcaggccc
     2761 ctgcgtccca ccgaggtgct ctcgctggcg gccaagtcct gaaccgagcg ccgacgaccc
     2821 acctgtggcc ggtggcgtcg gggctccggc tcaggagcgc cctgtccgcc gcttcatctc
     2881 ctcacacaga aggctggtca tcctggtgac ggggatcccc agcagggcgg gaagcgggat
     2941 cgttgtgtca ccgtgggaga aactctctcc agcctgcggt actgcgatat gcgctccacc
     3001 gggtaccccg cccacaggca cgagctcacg atcccgacgg ccacgaaccc gaccagtgct
     3061 ccgagctttg ctcgcaggac cgctgaggag ctggcgagga cccgggcgga gggatcggct
     3121 tgcgctgcag cggaggagat ggacccgaat tctccttatc ctcccgcagg acgaacaatg
     3181 gaaaatgcaa gagagaacaa catgcactga cgtcccgaca gaacacggaa ccaaacgtcc
     3241 ggggtacatc tgagcatttc cctccccacc cctagcacat gactttccac gtcatcgcac
     3301 cattgccacc acaattctcc gaaacattgt gcattaatga agcgcacccc gcatccgcgc
     3361 ccatgagctc atttccctct cggtcctcct ctgacagcct catggatcct ctgaggcgct
     3421 gaatcatctg ctcactgaga agtcggcctg atgtccggac tcgtgcccca ctgctattgc
     3481 gagccggcgc ggacccgagt ctcgaccggc gttcggtgat tcctggggga tcatttctgc
     3541 ctcgatacga gcgcccatcc gcgggcgcgg gtgcgttgct cccagaagct gcggtagggc
     3601 ccctcgacgg agacaagctc attgtggtgt ccccgctgag caatgcgccc ggcgtcgtcg
     3661 aggacgatga cctggtcggc ggcggcgatc gtctcaagct tgtgggcaat gacgatgagg
     3721 gtcgaggtgc ggcgcagctc ctgcatcgcg gcgacgatat tggcctcgtt ctcggcgtcc
     3781 agtgcgctgg tggcctcatc gagcaggacg atcggggctc gtttgagcag ggcacgggcg
     3841 atggagacgc gctggcgctc cccaccggac agggcccgcc cgccctctcc cacgcgcgtg
     3901 tcccagccat ggggcaggcg gtcgacgatc tccgtgacgc cggcgaggtc cgcggcccag
     3961 cgcacctggg cgtcgtcggc cgcggggttg ccgatgcgga tattggcggc cagggtgtcg
     4021 tcgaagaggt agacgtcctg gaagaccatg gagagctgct ccatgagctg ggaggtcggc
     4081 atgtcgcgca cgtcggtgcc gccgacacgc acggttcccg agtccacatc ccagaagcgg
     4141 gcgacgaggc gggcgatagt cgtctttccg ctgccggagg gacccacgat cgcgcacatg
     4201 gtgcgtgccg gcaccttcat cgaaaccccg gtcaggacgg gcgcgtcggg gcggtagccg
     4261 aagacgacgt cgtcgagctc gacgacgccc ggctcgggca gcgagctggg caccttgggc
     4321 tcggccatga gttcggcgtc catgacggca tcgaggtggt tcatcatctg gcgccgctcc
     4381 tccacaccca tgacggcggc tccgatgtcg tcgagcatgg tggtgaaacg caggcacatg
     4441 ccgatgacgg cgatggccac cagcggctcc atggcaccgg aggcggccag tgaggaggtc
     4501 aggacgatca tggcgacgac gacgatctgg ctcagcgcgc cgttgacgag gttgccggcg
     4561 gactcccacc acagggcgtg cctggaggcg cgtgccccgt cgtcgaaggc ggcagtcagg
     4621 cggctgtagc cggaggctgc ccgacaggat cgcagggcgc cctggcagcg ggcgatctcg
     4681 acgatgcggg aggcgagctc gcgctcggcg ggctcggaga tggacttgcc acggtccagc
     4741 agacggcgcg agaggcgcac gaatccggcg aacaggggcg cggccagcgt cagcaggagc
     4801 cccaggcgcc agtcccaggc ccaggagccg accccgacga ccacgcatgc agcagcagtg
     4861 gaggtgagca ggtacatgaa gtgggcggcg gactccccca gggccaccat ctcctggctc
     4921 acagcccggg acagggtacc ggcggagtcc gcggtgaacc agcgcagggg caggcgcgcg
     4981 atccggtcgc ccactgcgtg gtggacgtcg tgcatgaagc ccagcgcccc cgacatgccc
     5041 aggcgccgcc cctggaagtc acagacggcc gcaccgagac cgagaacgac cagcacgacg
     5101 agccagccac cgaaggacag cccccatcgg ggcgcaccgg tcgccagagc cactgaggcg
     5161 ggcagcagca ccagcagcgc cagtcccacc aggaccccgt tgactcccgc cagggcgatg
     5221 caccctcggg tctgtctcca agaggagtcg gtcatgagtc ggcggaagcg ggacagcagg
     5281 gagttcgccg gccgagagga cccgccgggg gtggagggca ccggacgcgt ggcccccgtc
     5341 cgcccatccc ggtcatcgac gcgggagggc gacgtcgcca ggaccctgcc gtcagccaca
     5401 ctgtcggcca caccgtcgtc cggactgtca gccgcgccgt cagccacact gtcggccaca
     5461 ccgtcgtccg gactgtcggc cgcaccgtcg gcgagtgcgg ggtcctccgt cctggtggcg
     5521 gtctcgtcac cgtccacctc cgtggcacct tcgatctcgc cggcctggcg tagcagagcc
     5581 cggtagtggg gctcatcggc caggtcatcg tgggtgccgg cggcgacgat gcgtccgccg
     5641 tccatgacgg cgatgcggtc ggcgccgcgc acggcggccg gccggtgggc gatgaccagg
     5701 acggtgcggt ccttgaccag ggcgctcagt gcctgctgga tctcggcctc ggactcgggg
     5761 tcggccatgg cggtggcctc gtcgagcacg atgacggggg tgttcagcag gatggcgcgg
     5821 gcgatggcga tgcgctgctc ctgtccaccg gacagtgccg tgtcctgccc caggacggtg
     5881 tcgtagccct gtggcagcgc catgatctcc tcgtggatgc gggccacgcg ggcggcggcg
     5941 cgcacctgcg ccaggtcggc ctcggggcgc ccgagggcga tgttctcgcg cacggtggtg
     6001 gcgagcagct gggcgtcctg gaggacgaag gagacggtgg agtacagggt ggactcgtcc
     6061 atgtcccgca ggtccacccc gccgatgcgg acggctccgg cgtcggggtc ggcgaagcgg
     6121 gcgatgaggg tggccagtgt cgacttgccc gagccggagg ggcccagcaa cgcggtcacg
     6181 gttcccggtt ccagggtcag gcaggcgtcg tcgacggcga ggacctcccc gtaggagaag
     6241 gagacgtggt cgatctcgac tcgctccgcg cggggctgtg cgggccggtc ggcggcgggc
     6301 aggacggggg tgtcgaggac ctcgcacagg cgcagggctg ccgcgccggc gagctggtag
     6361 gaccaggaga tcgaggcgat ggtgatgagg gcggcgggca ggaccagggc gacgagggtc
     6421 gtggccagga cctggggcag ggtgacggcc ccggcgtgga tgagcagcgc cccaccgccg
     6481 aggttgacca ggagcagcac ggggatggag acccaggtga aggacaggca ggtgacggtc
     6541 accaagggca tcgcccaggc gcggtagaag gcggagaact cgtccgcagc ggtgaggtag
     6601 gccgagtggg cgcgtcccac gcgtccgaag gccttgacca cgccgatccc ggagacgaac
     6661 tcgaccatgg ccgaggagat ggcggccagc ttgcggtcca tctccacggt cttctcgttc
     6721 atgccgcgca tggacaccga gtaggtgagc acgtagagga cgagtgcgga gacggccagc
     6781 agggccaggc gccagtcgat ccagaaggcg caccccagca gggccagcgg ggtgacgatg
     6841 gcgttgaggc gctcgacggg gccgtgggcg atgacggtgt ggacgagggt cgtgtcgtcc
     6901 tgaacggcct tgcgcaggcg cccggaggtg gaggcggtga accaggacag cggggcgtgg
     6961 gagatgcgcg caacgatgtc gcggcgcagg cggtcgcgca gggacaggtc ggccaggtgg
     7021 gtgatgagca gcgccaggaa gtacagcagc aggcgggtgg agtaggcgct cacgagcacc
     7081 atgaccacgc ctgacacctg ctgaggatcc gggctcaggc ccgtccggtg ggcgcgcagc
     7141 aggatatcgc cgagctggac cagtgcgatg tagggggcca ccgacaggac cgcggagagc
     7201 aggacgaggg cctgaccgat ccgcaggcgg gtgcgcacgg gggcgccgag gcgggcgatg
     7261 gctgcctgcc cctcgcgcga gcgctgggcg ttgccctgag ggggcggctc agctgcgtcg
     7321 tcaggcgctg ctgcaccggc tgagggcggc gacgacggcg cgggcgatgg atacggcgag
     7381 gctcccggag ctgacgactg tgtccgcgtg ctcatcaggt atcccaacct tccgtcgacc
     7441 ctaattctga atggctttca gaacttagtg aggtccacct tactctcgcc gctgaacctc
     7501 gggcaacagc tcgcacggac cattacggtg ctgccatgac acgatctgcg cgactgggcc
     7561 gaccgaccgg accgagaccg ggcttctcgc gcgacgacgt cgtcgatgcc gccctcgaga
     7621 tcggcatcgc ggagttcacg ctcacggcgg tggccaagca cctgggagtg gcggtctccg
     7681 ggctgtaccg cacgatctcc tcgcgcgagg atctgctggc cgcctgcctg gagaggatcg
     7741 ccgccgaggt ggagactccg ggcgccggga ggcgctggcc cgatgcggtg cgggcccacg
     7801 ccgaggccat ctgggcgatg ctggagcgct accccggcct ggccggagtc atcatggggg
     7861 tgccgtgggc ccaccagctc ttcgccaccc ccgtggctca ggcgtgccag gtcctggtcg
     7921 acggcggcct gggggtcgag gaggccgggg tggtcctgga cttcgtcggc gacaccgtca
     7981 tctccacgca cgcgcagatc gaggtcatgc gctcccccgc ggccccctcg gggctgggcg
     8041 gccccacagg actggaggag accagccggt tcgcggccgc cgccgggaac cctcccctgc
     8101 ccgaggcgct gacgcccaac gagagctggc tggagcgcgg cggcctggac cgcaagatcg
     8161 agatcatcat ccggggagtg gccgccggcc tgcccccgag cgcagcggat acgggaggga
     8221 agtcggcctc agggggcgac gtcagtgggc gacgctgacg tccaacggca tccccgagtc
     8281 cggggcgaag tccatagggc tgggggcgac accggcccgc acggccgctg accccagggc
     8341 tgcgatctgg gcgccgttgt cggtgcagaa gcgcagtgga ggcaggcgca gggtgatgcc
     8401 ggcctcctcg cagcgctcgg ccgccaggga gcgcaggcgg gagttggccg agtaccctcc
     8461 cccgacgacg agcgtgtcgc agccggtgtc caggcaggcc cggaccgcct tggccgtcag
     8521 ggagtcgttg acggcctcgg agaaggcggc acagacgtca gcactgggca cctcctggcc
     8581 ggagtcctcc agggactcca catagcgggc cacagcggtc ttgaggccgg agaaggagaa
     8641 gtcgtagcgg tagcgctcct tgtccttgcc cgcggccagc cctcgaggga agcggatggc
     8701 gccgcggtcg ccctcctggg agagccggtc cacgtgcggg ccgccggggt aggggaggcc
     8761 caggaggcgg ccgaccttgt cgaaggcctc gccggcggcg tcgtcgagag tgccgccgag
     8821 ctcgacgacg tcggtggcga cgttgcggat gctcaggagg ttcgagtggc cgccggagac
     8881 gatgagtccg acgaagcgct ccggcagggg gccgtcgacc agctcatcga ccgccaggtg
     8941 gccgatgacg tggttgacgc cgtagatcgg ccggttcagg ctcgcggcca gggccttggc
     9001 ggcggagatg ccgacggtca gggagccgat gagtccgggg ccggcgcaca cggcgacggt
     9061 gtcgacctca ctgaggtcga caccggcctt ctccagcgcg gcgtcgaggg ttggaaggaa
     9121 ggactccagg tgggcgcgtg aggcgatctc ggggatgatg ccgccgaagc gcgcgtactg
     9181 gtccatggag gtggcggtga catcggcgag gagctcgcgg ccgcgcacga gggccacgcc
     9241 ggtctcgtcg caggtggact cgatgccgag aatgaggggg tcgctcacgg ggccagacta
     9301 tcgcctggag agacggacgc cgaacaggcg cctatcgagg cctcgggtgc cgcatccttc
     9361 gtggcggcct tgatcgatgc cggcgttccg ctggcactgg tgacctccgc gccgatcgag
     9421 ctcatgcggg tgcgcatgga ggatgccggc gtccccattc ccccagtggt cgtctccgcc
     9481 ggcgacgtcg agcgcggtaa gcccgatccc gacccctacc tcaaggccgc cgagctcctg
     9541 ggcgtgccaa tctcctcctg cctggtgctg gaggatgctc cctccggcta cacctccgcc
     9601 cggcgcgccg gcgcacaggt cctcctcgtg ggcgacggcg tccccgaggc cggctcgcac
     9661 gtcccacgca tcgcggactt caccgggatc accttcacca tccatgaacg ccgagccggg
     9721 catgtcttgc gggcggggac atttcacgca gccgggcgcg tgtcgttccg ggcggggcca
     9781 ttcgacgccg tcggggacag caatcctgtc accgtacgcg ccacatgccc ccgcccggaa
     9841 gagagtgccc ccgcacgcgc agaaagtccc caccggcgtg cgctggtaaa aggtatgcac
     9901 gtagaacacc accgagccgg gcacttttcg cgacccccga cagaatgtct ggaggacgac
     9961 gcgagaagtg cccggctcgg tatggagtga ggcaggtgga tcagtgggcg tgctggccct
    10021 tccacagggc gtggccgaga tcccggttga ggcgcgagat gacctcgagc ggaaccgact
    10081 tggggcacac ggccgcgcac tcgccgatgt tcgtgcagcc gccgaagcct tcagcgtcgt
    10141 gctggttgag catgctcacc acgcgagcca ggcgctcggg ctgaccctgc ggcagcagac
    10201 ccaggtgcga gatcttcgca ccggtgaaca gcatggccga ggcgttgggg cacgccgcca
    10261 cgcaggcacc gcagccgatg caggcggcgg cctcgaaggc ggcgtcggcc ttctccttct
    10321 gcacgggcac cgagtgggcc tccggggccc caccggtgtt gaccgagatg tagccaccgg
    10381 cctggacgat gcggtccagg gcggagcggt ccacgatgag gtcgcgcagc accgggaagc
    10441 cggtggagcg ccacggttcg atcgtgatgg tggagccgtc cttgaaggag gggtcctccg
    10501 ccaggtggcg catgtgcaac tggcaggtgg tcgagcggat gggcccgtgg gcctgcccgt
    10561 tgatgaccac accgcactga ccgcagatgc cctcacggca gtcggagtcg aaggccaccg
    10621 gctccttgcc ctcggcgaag agctgctcgt tgagcaggtc gaggacctcg aggaagctca
    10681 tgtgctcctc gatcccgctc atggcgtact cctcgaagtg gcccttcgag tccttgttct
    10741 tctggcgcca gatcttgagc ttgatgttca cttgtaactc cgctgcttga gctcgatgtc
    10801 cttgtagacg aggtcctcct tgtggaggat cggcggctgg ttctccccgc cccactccca
    10861 ggcggcgacg tagaggaact cgtcatcgtg ccgcagggcc tcaccctcgg gagtctggga
    10921 ctccgcccgg aagtggccac cgcaggactc ccgccggtgc agggcgtcga tgcacatgag
    10981 ctcggccagc tcgaagaagt ccagcagtcg gccggccttc tccagggcct ggttgagctc
    11041 gtcggcctgg cccgtgatgc gggcgtcgcg ccagaactcc tccttgaggg cccggatctg
    11101 cccaatggcg tcgcgcagcc cggcatcgcg ccgttccatg ccgcagtact cccacatgat
    11161 gcggcccagg gccatgtgga agtcgtccac gctgcgggtg ccgcgaagag ccatgaggcg
    11221 ggcgacgcgc tcctcgacgg agcgcttggc ctcggcgatc tccggggcgt tggggtcgac
    11281 cttgcccagg cgcagcatgt ccgccaggta gttgttcatg gtgtcgggca ggacgaagta
    11341 gccgtcggcc agcccctgca tgagggcgga ggcacccagg cggttggcgc cgtggtcgga
    11401 gaagttggcc tctccggcga tgtagaggcc cgggacgttg gactccaggt cgtagtccac
    11461 ccacaggcca cccatcgtgt agtgcacagc ggggtagatg cgcatgggga cctcgtaggg
    11521 gtcatccccg gtgatgcgct ggtacatctc gaacaggttg ccgtagcggg cagagacggc
    11581 gtccttgccc aggcggttga tggcctcgga gaagtccagg tagacgccgc gacgcatcat
    11641 ccgctcgttg ccgttggcgt cgcgctcctt gatggccggt cccacgccgc gaccctcgtc
    11701 gcacatgttc ttggcctggc gggaggcgat gtcgcgcggc acgaggttgc cgaaggccgg
    11761 gtagatgcgc tcgaggtagt agtcgcgcgc ctcctcgggg atgtcgcgcg ggtccttgtc
    11821 gcagtcctcg gccttcttgg gcacccagat gcgtccgtcg ttgcgcaggg actcactcat
    11881 gagggtgagc ttggactgga agtccccgga ctgcgggatg caggtggggt ggatctgcgt
    11941 gtagcagggg ttggcgaagt aggcgccctt gcggtgcgcg cgccacacgg cggtggcgtt
    12001 gcaacccatc gcgttggtgg acaggaagaa cacgttgccg tagccgccac tggccagcac
    12061 gacggcgtcg gccaggtggg tctcgatctt cccggagacc atgtcgcggg tgacgatgcc
    12121 acgggcgcga ccgtcgacga tgatgagctc gaccatctcg tggcgacgga actccttgac
    12181 cgtgccggcg tgcacctgac gctcgagggc ctggtaggca ccgatgagaa gctgctggcc
    12241 ggtctggccg cgggcgtaga aggtacggga gacctgcacg cctccgaagg agcggttgtc
    12301 cagcagaccg ccgtactcgc gggcgaaggg gacaccctgg gccacgcact ggtcgatgat
    12361 gttggcgctg acctccgcca ggcggtagac gttgtcctcg cgggcgcggt agtcaccgcc
    12421 cttgaccgtg tcgtagaaga gccggtagac ggagtcgccg tcattgcggt agttcttcgc
    12481 ggcgttgatg ccgccctggg cggcgatgga gtgcgcccgg cgagccgagt cctggtagaa
    12541 gaagaccttg acgttgtagc cctgctcgcc cagggaggcg gccgcggcgc cgccggccag
    12601 gccggagccg acgacgatga tgtccagctt gcggcggttg gcggggttga ccagcttggc
    12661 ctcgaacttg cgctgctccc agcgccggtc gatcgggacg gagtgggggg ccttggtgtc
    12721 ggcgatcttc tcgccctcgt agtacaggcc gtcgatgagt tcagtcatag tcgttcactc
    12781 tcagtgggtc gccgtagcac actcggcgaa gtgctcggcg gaggagccga tcgcgtcaca
    12841 gaactgcggg tagtagtcgc cagtggccat gggggcatcg acatagccga agaggatcgc
    12901 cgtcggaaca gccatgaagg cggcgaacag cgcgaaggcc agcacgaagg cgatcagccg
    12961 gatgaagggg atggtgtttc cgcgcaccgc gcccagcgtc tgcagggcag accacacgcc
    13021 gtgccacacg tgcaggcaca gggcggccag agcgaccgcg tagatgagcc acacccacca
    13081 cagctggaag ccgtagtaca tgttgaggta ggcccgtccg tgcacgtagt gtccccccgg
    13141 cgtcagcgac agggtggtgt actgcaggat gtgccagatg atgaacagca ggaggatgac
    13201 gccgccccag cgcatggtgc gcatggcgta gcgggaggcg aagtactcgg cgccgggctt
    13261 cttgacggcg tacttgtcgt tgccgcgggc ccgcttgttg cgcgcccaca ggtggaaggc
    13321 gctgccggcg tgagccagga ggcaggcgat gagagccagg cggaggatcc acaggacacc
    13381 gccgtagggc atgatcggca ccagcagtgc tcgcaggaac acggcgtagt gatcgtaggc
    13441 gacctcaccc tcgaagtagt gcaggttgcc gtaggcgtgg aagaggacga agaacaggaa
    13501 caccagtccc gagatcgcca tcatgcgctt catgaagacg gtcgtggaga aggcggtccg
    13561 cctcttcagg gaaggagcag atgttttggc cacggcagaa ggctagccgg gcaccaggtc
    13621 ccgtaggtgc catctgcggc cccaccagcg acgttggtgt gacgatccgc ggaatcctgg
    13681 ggatctcacc gggtctcgat tcgtcattca acgccgcgga atatgctgac gccaccgtct
    13741 ggggccgcct tttcgtcacg ggggcgtcag acaaatctgt gaagtggccg acactcgtcg
    13801 cttgtcctcc cgcggcccgt gtttatctcc ggttgctgca gcatccatct gcttcttcag
    13861 gcccagcgca atccgtccag tcggactctg gagcttgctc ccggtgagtc gccccacgga
    13921 ctcaggcctc gccgggctca ccggcctcgg cccccaccgg ccccgggcgc gggcgcaggg
    13981 tcagccgcat gaccacggcg tcctccggcg gcgcctggta gtagcggcgg cgccggccaa
    14041 tgggaacgaa cccgtgcctg gtgtagagcc gctgggcggt ctcgttggac tgacgcacct
    14101 ccagcaggac atcggggcag ctcacctctc gggcggtgga gacgagctcg gtgagcatga
    14161 gggaggcgat ccctcgtccg cgcgcggccg ggatggtggc gatggtcagc aggtccgcac
    14221 tggtcagccc accggcgtgg tagagcccgg cgtagcccag gagccgtggc ccgtgcgacc
    14281 cggttccaac agcgcgatcc gcggcgtcat aggcgtcacc gtcgccatcg ctctcttcgg
    14341 actcgacgac gacgtagcgg cggtccgcca tcggcccgtg ggaggcctcc agctcggcgg
    14401 ccagcaggtc acggctccag gcctcggctc cgaagagctc gccctcgagt cgggcgacgg
    14461 cctccaggtc ccccgccgcc atctcccgca gacctggggc ccggcccgct ccggtcgcct
    14521 cgggcacctc agtgtccttc ttcgccccgg ggtcagcgca cgcgcttgcg agcggcaggc
    14581 atctgcacgt cggcgtggcg caggtagagc ggctgcgtgc tcagctgctc gccgcgctcg
    14641 aggcgggcca gggcgatgcg cacctgggtc agggcgtcgc cggagacggg ggccagggcc
    14701 ttctggcagg aggccatctc cgccagctcg gggtagaggg aggcaccgga gccggccacg
    14761 acgtcgatgt ctccactccc cccgcccggt cccggtgcct gctcggcgag gcgctgggcg
    14821 acctgggccg gagagcagac gatgatctcg gtcaggcggg tgacgtcgtc gggaccgttg
    14881 gcgcggaaga gtgccgtata gacctcgcgc ctgcgggcgt cggtggcgac cagaacgacc
    14941 ggccccgtct gcccctcctg ggctccgagc tcgtccaggg cgcggcgggc gacggcgtcg
    15001 aggctggaga ccccgtggac ggggacgccc cgggtgcgtc cgacgacccc cgccgtcacc
    15061 agccccgcac gcagcccggt gaagggggcc ggcccggtgg cggcgaccac ggcgtccagc
    15121 gggcgctcgg ccgcctcggg agccgacagg gcccgggaga gcatctgtcc gagggactcg
    15181 gcgtgacggc gggtatcggc ctgttcgtcc tggctcagca cctgcagggc gcgtgctccg
    15241 gcggcggagg gggcggcgtc gacgaccgcg agctgagtcc ccagggagga gtcgatggag
    15301 aggattcgca ccggaccagc ctatgccctc gggtctcgcg gcaggttgac gcggctctcg
    15361 gggatcgtgt cccccagggt ctcaccggcg gtcgcatcgg cgtcgtcatc ggccccgtcc
    15421 cccaggaggg acaggtcgat ggcggcgcgg gggatgcccc ggcgtactgc cgccccctgg
    15481 gtgtcggact cgtcccggct gagccggtcg gcgcgctcgg ccatgtcggc gcggttgcgg
    15541 gcctggcgca acggggcggt caccttgcgc tcgtgacgga ccgtgatgat gacggtgatg
    15601 atcccgacga cgacgaccgc caggaccggg ccccagatcg cccagccccc cgtggtggag
    15661 cgctcctcgc tctgccctgc ggaggtcttg ggcttggacc cggcgcgttc acgcaggatc
    15721 tctccgtagt cgcgcagctc gatggggccg gccaggcgcc gcgtggcggc ctcccccatc
    15781 gccgtcaccg tggtgccgtt cagcgagtac caggcgttgg cgttgcggtc gtggacgagg
    15841 tgggcctcgc ccatctggtc gacatcggtg gccaggtcgt cgtcgaagac gggggtgcag
    15901 gtggcgtgcc ccttgtcatg gaccacctcg agaagaccga cggacttgcc gcccgaggag
    15961 acggtcgcgg cccagtctcc ggtgtcgacg ggttgggcgg agggctggga tccgtcgagg
    16021 aagccggagg cccaggtgta gacgctgcgc ggatcaccca ccgtgatctc gccctgctcg
    16081 ccagtgctct gacgcacctg cgccacgcac tcgctctcca tgagcgtctt ggcctcgtcg
    16141 cgcgagtcgg cgtcggctgg gacacccgcc acgccgccgg ccgatgtgat cggcacgggg
    16201 cgggggccgg tgtcggcaac ggctcgggcc ggccccgggg tcaggaggca gacacccagg
    16261 agcgtcgccg ccgcagccgg caggagcagg cgccgaggac gccgggagcg ctgggcggcc
    16321 cggatgggga tggcgttgcg gaccggcgcc acggtggtgg gagtgttcac agcggcgctc
    16381 ccggctggca ggaggcgtct gcggccagtg ggctcaggtc gacgtcggcc cagcgcggac
    16441 cgacggcgcg cacgatgatc gtccggttgc cgtcgtcgac ctcgccgagg tccacgaccg
    16501 gctccccggc aaccgagccg gcgggagact ccgccccggc gggggcgtcc tcgggctgcg
    16561 ggtgctcggc gcgcacggct ccgtgggggc gcagtacctg gatctccagg cggtcggggc
    16621 tcagggcctc gaccttctcc tcgccccact cgaccagggt gacggcccgt tccagggagg
    16681 agtccaggtc aagggcgtcg atctcctcca gggaggtgat ccggtaggcg tccacgtgga
    16741 tgaggtcggg gccgtcggac agggcggggt gcacgcgggc gatgatgaag gtgggtgagg
    16801 agacccggcc gcgcacctca agggctgcgc cgatgccctg ggcgagcgtg gtcttgccgg
    16861 cccccagccc gccggagagc atcacgaggt caccggcgcg cagcaggcgg gccaggcggg
    16921 cccccagtgc ccgggtctcg tcggcgtcgc cggtggcgac ggtgatcccg ggggcggtct
    16981 gcggtgtgtg cggcgctggg ctcatattcc ctcctcttcc gtgcatggct ccgatggtgg
    17041 aaccggccga cccggcgggg accggcgata tccgacgtct gccgtctagg gtcgagagta
    17101 gtcgccggtg ccgggttccc cgatgtagca gcgcgggaca cgagctccca accgggtcac
    17161 gatctcgtag ttgatggtgc cgcaggcctg cgcccactca tccgcggtag ggacggcttc
    17221 ctggtctgat acctcggggg ctccccagag cacggcggtc tccccgaccc gggccggtgc
    17281 cggcaggggc gcgccggtct cgtccacggc cgggccaagg tcgataacca cctggtccat
    17341 gcacacccgc cccacgatgg aggtcatgag gctgccgact cccacgggac cggcggagct
    17401 ggcggcgcgc gggatgccgt cggagtagcc caggggcacg agccccaccc agcgatcagt
    17461 gggagcgctc caggttcccc cgtaggagac ggcctgcccg gcctcgatgc gcttgacctg
    17521 caccagcggg gactccaggc gcatggcggg ccgcagcccg agctcggcgc cggtggccac
    17581 ggaggggtcg ggactcagcc cgtacaggcc gatgccggcg cgcaccaggt ccatgcgggc
    17641 ctgcgggtgc cacaggagtc ctccagtggc ggcgaggtgg tgagtgggtg ggttgaggcc
    17701 ggcggcgagg acgacctgct cggcctgccg gtagcgctcc aggtgctcct cggtggagcc
    17761 gctggccggc tcatcggcgc gcgacagatg cgaccacagg ccgacgacgt cgaccgttcc
    17821 ctcatcctcg gcccgcctca gcgcggcggc cagggcgggc agctcctcga cggtggcgcc
    17881 gccgcgcgac atgccggtgt cgaccttgag atggagacgc gccaccctcc cctgcgcccg
    17941 ggccgccgcc gacagggcct cgagctgggg cagggtggag accgacaggt ccaggtcggc
    18001 cgccagggcg gcacgcaggg gcgagtcctc ggcggccgca cgatcaggct ccatgacggg
    18061 caggagccag gtgaggagcc ggggggcctg cgaggcggac tcccccgccg ggcggctcac
    18121 accggcctcg tccagaaggg cacgcagagt cagggcctcg gcgagctggg ccacccccag
    18181 ccaggaggct cccgccgaca gagccgtcag agcgaccggc cccagcccgt gaccgtaggc
    18241 gtcggccttg accacggcca tccacggcac gcccgccacc tgtgccaggc gccgcccgtt
    18301 gtgggccacg gccgccaggt cgacgacggc ccgcgaggta gtggccgccg gcggtcgcgc
    18361 gcactgggcg actgccgggc gcggagcggt ggacgggggc attgcgactg agtccgggga
    18421 ggtggtcacg gcgcgattgt cgcactgggg ccggtagcgc cgctgtttcc tggcgcacgc
    18481 ctccggtcag gagtcctgac ggataccgcg tggctgacgc gtctcaggcg tggggcaccg
    18541 cctggagcca gttgagctcg aggcgggccg ggccgagggc aacggcaatg tccagggcgg
    18601 cgatcgggtg cccgccggtc cccgctcccc cggcgccctg cgggcttgct gcggcatagg
    18661 cccccgcgag cgcgtgcagt ctgacgccgg cggccaccga gtcgaccagc gcgtccagga
    18721 ccaggtccgc cccggaggcg tccggcgcgc cctgctccca gcgggcggcc gcgccggcca
    18781 ggacggctcc gaggatcccg gccagcacgt ccccgcttcc ggcgctcgcc atccaaccgg
    18841 gtcctccgtc cacactgacc agggggcgct gcggcgcggc gatgagggtg gtggccccct
    18901 tgagcaggac ggtggcgccg gtgcggcggc agagctcgcg ggcggcgagc cccgggtggg
    18961 cctcgacgcg ctcgcggctc cagcgacagg tctcctgcgc cggcgtcccc tgatcctcca
    19021 gcgcgatcag cagcgcggcg gcctctccag cgtgcggggt cagcacgtgc agcggcgtgc
    19081 agctcaggtc ctcggtgagg agctcgggca ggatgctcag ggcgccggcg tcgacgacgg
    19141 tggggacccg ggtggggcac tgccggtcct tgccgcaggg acccagggtg gaggcgagga
    19201 cggtccgcac ctcatcggcc ctggtggcgt cagcggggtc gatgcccggc cccaggacga
    19261 gcgcctgaac gcgtccggcg gcggggacca cctcggggcg ggcggccagg acgaggtcct
    19321 ccacgcgtct gggggcggac aggcgcacca tgccggcgcc ggcgcgtacc gcgccgctgg
    19381 cggccaggac ggcggcgccg gggtaggact cgctgccggc ccacaggccg accacgccgc
    19441 gggtgtactt gtggtcgccg gggccgggct cgccaacggc gcgggtcagg tagtcgccca
    19501 gggcgccgtc gacggggcgg cgggccaggg gccggctcgt gggcgcgggc agtccgaggg
    19561 ggacgacttc gacgacgccg cacaggtgcc gggccggggg caggcactgg catcccttga
    19621 ggcaggtgaa ggtgacggta tggtcggcgg ccaggaccgg gccactcact gtgccgtcgt
    19681 cgacgccggt tccgctgggc aggtcgacgg cgatgactcg cagcgggcgg cgccccggct
    19741 ctccggcggc gatgagcggg gcgatgaggg cggcggcgtc aggtcgcagc gccccggtgg
    19801 cgccgatgcc ggtcagtccg tccaggacga gtccgccgtg gacgaggaag gcctcgatag
    19861 cggtcatggc ctcggcggag tcctggccgg ttccgtcgtc gctgcggtag ccggcgccgt
    19921 gaatggtgac gccgtggccg cgggcctcct ccagggcgac gggatggggg tgctcggtgg
    19981 cgagcacggc gctgaccgcg cagccgctgt gggcgagcag acctccagcc aggagggtat
    20041 cggccccgtt gtgtccaccg ccgactaaga ggagtaccgg ggccccggag atccatccga
    20101 ggccggtctg catccccgcc gcctcacctg ttcctcccag cggcgtcgcc ggggacaacg
    20161 gtgaggctgg ggtggcggcc gcccccatgg ggctcatcga ggtcaacggc gccggaaccg
    20221 gccgggcggg ggccaccgcg gtgcccgcgg tgccggctcc ttggcgcagc tcacgcagtg
    20281 ccgcccgggc taccgcgtgg gcggcggctc tcatgtagcg gtcagtgcct gcggtgacgg
    20341 gggcctccgc ggccgctatc tcctgagcag gccaggcgca ggtggtgggg tcggtgacgt
    20401 cgtgggaacg cgggaggtcg ttgaggtcac tcatccgtcc cattgtcctc cgctccgctc
    20461 tcctcgcccc tccaacacgg ctttgagacg ggcagtttca cagagcaaga cctcgcgggt
    20521 ggccgccggc ccgcattgcc cgtccgcggc caagcgccaa gaagttgtct cttccagaat
    20581 tggtggcgcg ttcacccctc gcgctgcccg ctcacccggc acaatggccg agtgatccgc
    20641 gctgtaggga ccgacctggt tgatatcccc cgcctcgaag gctacatgga ccgggtaccc
    20701 ggcctgcgcg agcggctctt cacccccgcc gagctggccg cctgccagaa acgggccgcc
    20761 tcactcgggg cgcgcctggc ggccaaggag gcggttctca aggccctggg ttcggcctac
    20821 gccgagctcg gactggacgc gccccagggc tgggagtacc aggacatcga ggtgacctcc
    20881 acgcccggca ccccaccgcg cctgcgcctg accggggcgg ccgccatggc cgcccgccag
    20941 gccggcatcg gccactggca catctccctg gcccacgacg gtggtatggc ccaggccttc
    21001 gtcgtcgccc aggccgatca cgtcgacaac gacgacgacc tgactctgtc ctctcaacgc
    21061 tcacaggccc gcacgaagca gcagatccgg tccccgcgcc cagccctgta gacgacggtg
    21121 ccgagcccgg aatacgggct cggcaccgtt gagggtcgag ttaaggggcg agtcgacgtc
    21181 tcggcgtcgg tcctactcga cggtgacgga cttggccagg ttgcgcggct ggtcgatatc
    21241 cagccccttg gccccggcca gcgcagcagc gaagatctgc agcggcacca cggtcagcag
    21301 cggccacagg atcgtgggag tgacgggcat ccggatgatg tggtcggcga agggctcgac
    21361 gtcggtatcc ccctcctccg cgatgacaat ggtgcgcgcg ccgcgggccc ggatctcctg
    21421 gatgttggag atgaccttgt cgtgcaggac agggcggcgc ggggtgggca cgatgacgaa
    21481 gaccggaagg ccctcctcga tgagcgcgat cgggccgtgc ttgagctcac cggcggcgaa
    21541 gccctccgcg tggacgtagg cgagctcctt gagcttgagc gccccttcca gcgccaccgg
    21601 gaagccgacg tggcggccca ggaacaggaa ggaggacttg tccgccagct cggagcccag
    21661 ctcacgcacg cgggcctcct cgtggtccag gacgtgctgg atgcggtccg gcatggcggc
    21721 gaggttgtcc aggtactcgg cgacctcgtc gggccacttg ttgccgcgca gctgggccag
    21781 gtagagcccc agcaggtagc aggcggtgat ctgggcgagg aaggccttgg tggaggccac
    21841 ggcgacctcc gggccggcgt gggtgtagag gacggcgtcg gcctcgcggg cgatggtcga
    21901 gccgtaggtg ttgacgatgg ccaggacctt gctgccctgc tcgcgggcgt gacgcacggc
    21961 ctggatggtg tccatggtct cgccggactg ggagatggcc acggtcaggg tcttctcgct
    22021 gacgaccggg tcgcggtagc ggaactcgtg ggcgagctcg acctccacgg ggatacggca
    22081 ccagtgctcg atggcgtact tggcgacgtg cccggcgtag gcggcggtgc cgcaggcgat
    22141 gacgatgatc ttgtcgacgc tgcgcagaac ggcggggtca atgcgcatct cgtcgagctg
    22201 gagctcaccg cgctcgtcga cgcggccgcg cagggtgtcg gccacggcgg tgggctgctc
    22261 gtggatctcc ttgtccatga aggtgtcgta gccgcccttg acggcggcgg aggcgtccca
    22321 ggagacctcc caggccttgg gctcgacggc gttaccgtcc ttgtcccaga cgtggacggc
    22381 gtcggcggtc agcaggagga cctggtcgtc gtcgacctcg gcggccttct tggtgaaggc
    22441 gacgaaggcg gcgacgtcgc tgcccaggaa gttctcgccc tcgcccaggc cgatgaccag
    22501 gggactggag cggcgggcgg cgacgatcgc cgcgggggcc aggtcggtga cggccagcag
    22561 cgcgaaggcg ccctcgaggc gggcggtgac ggcctgcatc gaggcgacca ggaggtcggc
    22621 gacccgggtc gggtcggagg cggcggacgg gtcctggcgc agacgggagg tgaagtcgat
    22681 gtccaggacg tgggcgacga cctcggtgtc ggtgtcggag acgagctcac gcccagcggc
    22741 ctcgacctcc tcgcgcagcg gacggaagtt ctcgatgatg ccgttgtgga ccacggcgag
    22801 gtggccggcg cggtgggggt gggcgttggc cgtcgtcggg ccgccgtggg tggcccagcg
    22861 ggtgtgtccg atgcctgcgg tggcgggagc cggcggggtg gcctcaagga tggcgcgcag
    22921 cccggagagc ttgcccgcct ccttgatgac atccaggccg gagggcccta ccagcgcgac
    22981 gcccgcagag tcgtagccgc ggtactccag acggccgagg ccatccatga gaacggtcag
    23041 ggaacgggag gaaccagttt cactcagagg gccgacgtgg ccgacaattc cacacatgct
    23101 ccgatcgaat catgccggcg cggcgttgac aacgagcgca ggcacacgtc gatgtgatct
    23161 cggcgtgatc tctgcgtgat cccgttcccc gccagcaccc cacaggcgcc ccgacgggcc
    23221 ccattcgttc ctcggggatt gtccgccggg cgtcttcatt tgcgacactg tgtcggtgac
    23281 atccgagctg agcgacccga gtgacctggg tattccgggc gcctcgccct acatcgagct
    23341 ggaccgggac cagtggtccg ccctggcgtc ctcggcgccg ctgccgctga cccaggccga
    23401 tgtggagaag ctgcggggac tgggagaccc catcgacctg gcggaggtcg acgccgtcta
    23461 ccggcccctg actgccctgc tggaggacta catcgccacc tcgcgcgagc gggcgcaccg
    23521 caccggcgcc ttc
//
