LOCUS       NZ_KK073872.1          24000 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KK073872.1 Cloacibacillus evryensis DSM 19522
            CloevDRAFT_Scaffold1.1, whole genome shotgun sequence.
ACCESSION   NZ_KK073872
VERSION     NZ_KK073872.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:26:22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1024713
            Orig. end    :: 1048713
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24000
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1034713:1038713]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14000
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /neighbourhood="10000"
                     /product="Arginine2putrescine"
                     /protocluster_number="1"
     cand_cluster    1..24000
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [AdoMet_dc, Amidinotransf,
                     Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="chemical_hybrid"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..24000
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Arginine2putrescine"
                     /product="Putrescine2spermidine"
                     /region_number="7"
                     /rules="(minimum(3, [AdoMet_dc, Amidinotransf, Arginase,
                     OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or
                     ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and
                     minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     protocluster    850..24000
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1035562:1038713]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      10850..14000
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="2"
     CDS             2411..3463
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SBP_bac_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_881"
                     /sec_met_domain="SBP_bac_1 (E-value: 4.5e-14, bitscore:
                     50.6, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNLSDQIGKAWKFALLLIAVTAVFTAVAAHAAGKELVVYTALEN
                     EQINKYLATFKEENPDIDVKIVRDSTGIITAKLLAEGARTPADVVWGTAASSLLVLEKK
                     GLIEPYAPKGLARVEKMLKDTANPPAWVGIDAWECAIVVNTAEAKAQGLPAIKSYKDLL
                     RPEFKGKIVMSNPNSSGTGFLAVSGILQLMGEKAGFDYLDKLHENIALYTHSGSAPAKK
                     AASGEFPVGISYGYAGVNQKKKGAPVEIVFPVEGSGWDVEANALIKKKNIKPEAKKFLD
                     WAISDKAINALKDDYAITAVKVSGAIPEGYSKSPLSQLVKKNDLRWAAQNRDRLLKEWA
                     SRYEGKTEAK"
     CDS             3474..4442
                     /locus_tag="ctg1_882"
                     /transl_table=11
                     /translation="MTTLRARNITKRFKGTTALDKVSFEIRDGEFVCILGPSGCGKSTL
                     LRALAGLEAIDGGTIEIGGRDVTCEPPSERNFGIVFQSYALFPNLNVEENIAYGLWNKG
                     LAKDEIAARVAGIIEMTGLGGHNKKYPQQLSGGQQQRAAICRALVLNPEFLLLDEPLSA
                     LDAKVRLRLRREIRRIQQRFAITTIMVTHDQEEALSMADRIIVMNEGRIEQMDTPQALY
                     DAPVNGFVADFVGTANFVGAGRAIRPESLCLSKSLSDSAVQAEVCDVEYRGAFYRLEVD
                     THVGHLMIDIPSQQSDARVLRLGSRLYIDIPQDKVIMLKSA"
     CDS             4445..6091
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 33.6; E-value: 1.1e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_883"
                     /sec_met_domain="BPD_transp_1 (E-value: 9.1e-12, bitscore:
                     42.6, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIKNANRLESVLLIISLCLLFTAVAAPMAVLFAKAFTDFDGAY
                     IGLANFREYFASPHLVGALWNSLAISAVVSLISLLLAFIYAYALTRAEVPAKGFFKFIA
                     LLPLCAPTMMFGIALIYLIGNKGVITMLGLKLPLYGPLGIIVSEVVYTFPQAFLILYIT
                     LSYTDNRLYEAARAMGTAPLRILRTVTLPGAKFGLVSAFLVAFTLCFSDFGAPKVVGGN
                     YSVLATDIYKQVIGQQNFGMGSVVGLLLMIPAVVMFVTERLTASDNGVTVSSRSMAYRV
                     IPHRGRDAALTLFCALAAGFIITLFAAVLAASLIKAWPYNMVPTFEHFTVDSPATGGLS
                     SFFNSLVTALLTAFCGTAFVFMNAWLVEKSAANRLLRQAENLFSLIPLALPGLSIGLAF
                     IFFFNMEGNPLNFIYGTAAVLVLANVVHFYSVPYVTASSALKKLDREIEAVAASMAVPS
                     YRTLFKVTMPMCRAAIFETALYFFVNAMVTISAVVFLYPPDFKLASVAIVNMEDAGDIA
                     PAAALSVLVIFVNVAAKLLYEYTFVMKRSGK"
     CDS             6091..6885
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_884"
                     /sec_met_domain="HAD_2 (E-value: 1.8e-11, bitscore: 42.0,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNGKKIKCVILDWAGTTVDFGSMAPLRVFSDIFAQRGLRLETDE
                     LRAPMGMPKLEHIRELLRMERPARLFREKYGRMPIDDDALGMYAAFEPALLKILHDFAE
                     PLEGVCGAVRELRETGVKIGSTTGYTRKMMDIIAPLAKAAGYAPDCIVTPDEAVEGRPA
                     PWMIFKNMERLGVYPPSSVVKAGDTAADIREGKNAGVISVGILRGSNELGLTRSEFESL
                     PAKEVDERRQAARERFYLAGADYVLESIRELPAFVREMDKDD"
     CDS             6878..8008
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_885"
                     /sec_met_domain="Aminotran_5 (E-value: 1.6e-20, bitscore:
                     70.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTENKYLLLTPGPLTTTAAVKAAMLRDWCTWDRDYNDLVEKLRGD
                     LVEMALRDRAKRAGYTAVLMQGSGTFAVESVIGSVIPQGGKLAVLSNGAYGRRIAEIAG
                     ILKVPAVELRFDECERPDAETLAVMLDDDPAVTHVAVVHCETTTGILNDIESVARAAKS
                     RGKKLIVDAMSSFGGIPLFMDVLEIDFLISSANKCIEGVPGFAFVLANRAALSECAGLA
                     RSLSLDLYGQWKTMEEHGGKWRFTSPTHVVCAFAEALRELKAEGGAAARNRRYAANRDM
                     LVRGMEGLGFKALLPAELRSPVITSFLYPDGIGFDFAEFYESLKRDGYVIYPGKLSERD
                     TFRIGNIGDIREKQITGLLAAVERYVKRSEARPLCA"
     CDS             complement(8166..9071)
                     /locus_tag="ctg1_886"
                     /transl_table=11
                     /translation="MYWEIGAYVSNKVKNGGWGKSIVTDFARFMESERPDIKGFSASNI
                     WRMRQFYETYSGSEKLAPLAREISWTQNLIIMSRAKTDEAREFYLLLCGRNNYTKRELE
                     RQIDSMLFERTLFSDERNKLFLAKNTGLTALRDSYVLEFLNVPENHKEKELRKSIVANI
                     RDFILEFGKDFTFVGEEYLVQVGNKDFHIDLLFYNRELSCLVAIELKVTDFKPEHLGQL
                     EFYLEALDRDVKKPSENPSVGLILCAGKDDMVVEYALSRSLSPTLVADYQLHLPNKNIL
                     TEKLRELKELADVETGEDDS"
     CDS             complement(9643..9987)
                     /locus_tag="ctg1_887"
                     /transl_table=11
                     /translation="MKKVKITVLKTTLDKELAEEYGAEGLGPCPMLREGQTFHADYAKP
                     EGFCDEAWKAIYQYVFALAHGSGNGLFYYGDWIRKPGVAICSCNDGLRPVIFKLEATDE
                     DSRIDYEPVR"
     CDS             complement(10001..10849)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: Arginase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_888"
                     /sec_met_domain="Arginase (E-value: 3e-75, bitscore: 250.8,
                     seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METNIQGFIGCSSPYAEARAVLFGAPFDSTTSFRPGTRFGPAAMR
                     SESFGIETYSPYQDRDLEDLGVFDAGDLDLPFGNAAAAIEAIEAAAAEILADGKTPVLL
                     GGEHLVTLGAVRAAAKKYPGLRLIHFDAHADLRSDYMGESLSHASVIRRCHDILGDGRI
                     FQFGIRSGSREEMRWSAGRTTMEKFRAETVGAAVKEIGEAPVYITLDLDVTDPAEFPGT
                     GTPEAGGLRFAELLKALLALRGLNVKAFDLCELSPHYDNSGASTALACKTLREMLLAYC
                     G"
     CDS             complement(10850..11701)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_889"
                     /sec_met_domain="Spermine_synth (E-value: 6.8e-58,
                     bitscore: 192.7, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 9.3e-18,
                     bitscore: 61.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYTEEHTPTVRFSIKVKKQLFGGKSPFQQIDVFDSEEFGRFF
                     TLDGLMMLTEKDEFIYHDMIVHVPMATNPDVRRVLVIGGGDGGTVRELTRYKTIEKIDM
                     VDIDEMVVKVCRELLPFTSRKLGDPRVTLYFEDGLKFVRTASEKYDLIIVDSTDPFGPG
                     EGLFTKEFYGNCFKALTDDGILVNQHENPYYDSYRASMKRAHQRIEDFFPVCRVYQAHI
                     PTYPSGHWLFGFASKKFDPIKDLDAAAWNGLGLETRYYNTDLHVGAFMLPNYVKQALEL
                     KD"
     CDS             complement(11715..13136)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: OKR_DC_1_7_arginine"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_890"
                     /sec_met_domain="OKR_DC_1_C (E-value: 7.4e-11, bitscore:
                     40.0, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 4.8e-127,
                     bitscore: 421.4, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLEALAEYRKSRVVPFDVPGHKQGRGTPELTEFLGKACLSVDVNS
                     MKPLDNLSHPTSVIKEAEALAADAFGADDAFLIIGGTTAAVQAMIMSVCKRGDSIIIPR
                     NVHKSAINALILCGIAPIYVDPGIHPELGISLGMCADDVEAAIAAHPEAKAVFVNNPTY
                     YGICADLGRITEAAHRAGMAALVDEAHGTHFYFASDMPLTAMEAGADMAAVSMHKTGGS
                     LTQSSLLLMKRGRVRPDYVRTVINLTQTTSASYLLMSSLDIARKALATEGKETFSRVVS
                     LAEYARGEINKIGGYYAFSREIIDGKYICGFDTTKLSVNTLKIGLAGVEVYDLLRDDYG
                     IQIEFGDMGNMLAIISVGDNHYAIERLVASLSEIKRLRGREGLHLLDHEYIPPVVRMTP
                     QEAFYAPSRPLPIREAVGKISAEFVMCYPPGIPILAPGEEVTREALDYILYAKKKGSLV
                     MGPQDMELNDLYIVK"
     CDS             complement(13188..14000)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2putrescine: AdoMet_dc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: AdoMet_dc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_891"
                     /sec_met_domain="AdoMet_dc (E-value: 1.9e-27, bitscore:
                     93.2, seeds: 266, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKDKIQLYGFNNLTKTLSFNIYDICFAKTDREKQDYIAYIDEQYN
                     SERLTKILCGVTDIIGACVLNISKQDYDPQGASVTILISEESVPPAQIDESCNMGRWAE
                     KINEERETVVAHLDKSHVTVHTYPEFHPNNDISSFRVDIDVSTCGKISPLNALNYLIGQ
                     FDSDIIALDYRIRGFTRDIDGKKYYKDHEINSIQNYIDEATLRRYDAIDVNVYQSNIFH
                     TKMMLKEIRLADYLFNIDPRELPPEERLSITDRITKEMLEIYYGMNMY"
     CDS             14337..15008
                     /locus_tag="ctg1_892"
                     /transl_table=11
                     /translation="MSLKDAANLYFNPGCALSIYRPENVKTIFDYLLKNFPEIEMHDIC
                     CRHDPKLPGGSVIINVCAGCGKRFGSLYDGVSTISLWEVIRELDNFPFPDYKGMEVSIH
                     DPCPVRNEPGVHEAVRAILKKMKIRIVEAENIGTNSVCCGDSLYPSCDKEKILAAMKRR
                     ADSMPCENVAVYCVSCVKAMHIGGKVPRHLVDLLLGKATDPQECDIERWHNKLDAYIQT
                     H"
     CDS             15049..15588
                     /locus_tag="ctg1_893"
                     /transl_table=11
                     /translation="MYEAVITNDANYDGSFFYGVKSTGIFCRPSCQSKKPLRENVCFFH
                     SAGEAMKEGFRPCKRCRSDLLSYRPMEKIAGLVKKHLDELYERQTSWNGELREIGLSER
                     RVVQIFKDVYGMTPKAYMDILKLREAKRLLSETDKKVIDIAASVGFGGLSAFNRFFKEQ
                     AGCSPAAYRKMYKKQA"
     CDS             complement(15704..16909)
                     /locus_tag="ctg1_894"
                     /transl_table=11
                     /translation="MKKAMLLLFAALLALFVSTAAMAAEAPFHIGIVTGTVSQSEDDLR
                     GAELMIKKYGDVAKGGMIQHLTYPDNFMSEMETTISQIAGLADDPKMKVIVVNQAIPGT
                     AEAFRRVKEKRKDILCFAGEAHEDPNVITSVADMAINADFVSRGYLIIDTAKKLGCKTF
                     VHISFPRHMSYETLGRRRAIMEQACKDLGIKFVFETAPDPTSDVGVAGAQQFILEKTPA
                     WVKKYGKNTAFFCTNDAHTEPLLKQLAKYGGYFIEADLPSPLMGYPGAFGIDLTKEAGN
                     WPVILKKVEKTVSDSGAKGRMGTWAYSYGYTNSAALAEFGKRIVDGKAKLNSKKDLLAC
                     YAEFTPGAKWNGQNYTDLGTGVTKKNMMLIYQDTYILGKGYMKATDVKVPEKYQKIKFS
                     GK"
     CDS             17330..18436
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M24"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_895"
                     /sec_met_domain="Peptidase_M24 (E-value: 2.6e-67, bitscore:
                     224.1, seeds: 437, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKKKRVERLAQTLKDRGIDALYIGPSTDLEYVGGLDTQPDERVR
                     GLMVAKDARCFAMTPLLYKEEIVKAFEDVPFYAEWNDHEGFTGAFRRGCEHLGIVGGRI
                     AFNDGVRAVDMLAVRDAMPMEMVNGADLLAGQRSRKDEEELEVLRESSRIVDKVVAKLQ
                     KFIRPGIKERDVAKKIPEFFEEEGVTQMSFNPIVASGPNGSMPHYSGGERVIGENDIVI
                     LDLGGRYKSYCSDTTRTLFTGTPTEEMKKVYEIVKRSQAAGEAAVRPGATGQDVDRAAR
                     QVIIDAGYGEFFFNRVGHGVGLAVHESPYMIEGNDVPLAPGNVFSVEPGIYLPGKFGVR
                     IENLVAVRPDGSGEALNHFTRELTICGD"
     CDS             18535..19725
                     /locus_tag="ctg1_896"
                     /transl_table=11
                     /translation="MRRATVFLFALIAASFMATAAFAAPAFHIGVATLTVSQAEDTYRG
                     AERLIKEYGDVANGGMIKHVTMPDNFMSEMETTISQIVGLADDPKMKVIVVDDAIPGTT
                     EAFRRVKEKRKDILCFAGEPQEDPNVITSTADFAVGVDNIMRGYLIINTAKKLGAKTFV
                     HISFPRHMSYELLSRRRAIMEQACKDLGMKFAFETAPDPTSDVGVAGAQQFILEKVPAW
                     VQKYGKDSAFFCTNDAQTEPLLKQVAKYGAIFVEPDLPSPLMGYPGAFGIDLKKEAGNW
                     PAIMKKVEKTVVASGGKGRMGTWPYSYGWSTVCALAEYGKRITEGSAKLYNLKDLWKCY
                     DKYTPGAEWNGAPYYDMAKQMKIKKFVLVYEDTYVFGRGYMGVTKEKVPEKYIKLK"
     CDS             19915..21525
                     /locus_tag="ctg1_897"
                     /transl_table=11
                     /translation="MSMEIPLLKMENIGKEYFGNRVLQDVTFSLRPGEIMGLVGENGAG
                     KSTLMNILFGMPVIQETGGYEGKIMIDGQEVRFKDPLDALEAGIGMVHQEFSLIPGFTA
                     TENILLNRESVKYNALVEVFGERLMTLDRPEMRERAEKAIKTLGVELSPETLISEMPVG
                     HKQFTEIAREIDRSKTRLLVLDEPTAVLAESEATVLISALKTLSKQGIAIIFISHRLQE
                     IIDLCDKLIVLRDGRVIQEACTKETNVRQIAAWMVDRKGDKAGEEKAEKKEKTIGDVIL
                     RTEHLWVDMPGETVRDVSIEVRQGEILGFGGLAGQGKVGISNGIMGLYAAGGKVFLRGK
                     EIKLNDPDASLKEGMAFVSEDRRGVGLLLEEGIDWNITFTAMQVQEKFIRKLAGGLVKW
                     RDDKAIEECTREYIKSLEIRCTGPAQRAIELSGGNQQKVCLAKAFAVSPEILFVSEPTR
                     GIDVGAKKLVLDTLRRVNEEDGTTIIMTSSELEELRSICDRIVIINEGRVSGILPASAP
                     AEEFGLLMLGHVEEPAAVN"
     CDS             21551..22597
                     /locus_tag="ctg1_898"
                     /transl_table=11
                     /translation="MKNKLQEFIENAGWPRVIIALFLCALFVAAPFVGVRIDASLSDTL
                     VRVGMNGILVLAMVPMVQSGCGLNFGLPLGIIAGLLGAVTSIQIGIRGSVGFLLAAAIA
                     IPIAVVLGWLYGQLLNRVKGDEMMIATYVGFSSVALMCIAWLLLPYTSPTMIWGYGGSG
                     LRTTISVEGYWLNALSKYVNIQIGEFFYVPVGMFLFFAFVAFLVWAFFRTKIGTAVTAV
                     GSNPEFARASGIDVDRMRTISVILSTVLGAVGILVYEQSFGFIQLYMGPFYMAFPAVAA
                     ILLGGASVNKATMVNVVVGTFLFQGILTMTPSVINSVMQTDMSEVIRIIVSNGMILYAL
                     TRKVTVKR"
     CDS             22597..23688
                     /locus_tag="ctg1_899"
                     /transl_table=11
                     /translation="MAKRNRELKSMLADYAVPIVFIGLSAIAIPLSGFSATYLIQEMFT
                     RLARNSFLVLSLLIPILAGMGLNFGMVLGAMAGQIGLIFVTDWAVVGWEGMLLASIVGM
                     PIAILLGYICGAVLNRAKGREMVTSYILGFFINGVYQLIVLYGMGNILPISNPQLVLSR
                     GYGIRNAINLTGVRHVLDNLIPFKIGTIDVPVATFILIGIFCLFIVWFRRTKLGQDMRA
                     LGQDMAVAESAGIPVERTRIIAIVISTVLACFGQIIFLQNIGTMNTYNSHDQAGMFAIA
                     AILIGGASVSRATITNVFVGVVLFHLMFVVSPMAGKELIGQAQLGEYFRVFVSYGIIAL
                     ALVLHAWRRQRDKIEARRSLRGE"
ORIGIN
        1 gcgacagaaa tcggtcaggt taatattgga gagctgttta atgaggcggg ggattacatc
       61 ctgtccgaag atatcgtttt gagcggcgac acgaaggcaa tagagctttc taaggatata
      121 gaggtcacgt tggacctgaa tggacatact atatccgctg atacaagcaa atacagagaa
      181 cttgaaagta atgcattgaa gtatcctgga agtatcattt acgcgacatc aggagacatt
      241 actatcaaag atggcgttgg cggagggaaa atatgtgata ccagcgcggc agaatatagt
      301 aaacataacg atggcgtgat acgcgtcgaa aaaggaactc atctgaccat cgaaaaagcg
      361 ataatagagg tcaaagaagg tattgggatc acaacctatg atgacggtac cagagtgacg
      421 tttaaagacg gcgaaataaa agtcgaatat ggcttcggta taggcacgaa tgggctaaat
      481 attaccgaac ctggttccgg catttacgtg gagggcggaa cgattactgt agctagcgcc
      541 gattctgcgg caatttatca ccctagcagc ggaactttaa gtatatctgg cggcacgctg
      601 tcggctgcgg acggcattca ggtaaaagcg ggaagagtga taattacagg cggaaccatc
      661 acggcaacgg ggaaacataa tgtcccgcta gacagtaagt tctcaggcgg cggaacaaac
      721 gaacttggca atgcactgtc cttgatatcc catgcgagtt ataaaggcca gtccatggat
      781 gttgcgatct ccggttcggc gatgctgata gctgaacagg atgacgctat tggtgtttat
      841 gtgaacagcg gagacgtgag ccacgtaaat tcgtttgtaa ttaccggcgg cacctacagc
      901 agcgacccgt ccgcctatgt cgagtctcct tatgtagtca agcaggtcga aggtaaatat
      961 gtcgtcgccc tcgccagcgt cgccgtcact ccgacagccg ccgaactcgt actcggcctt
     1021 acgccgacgg caaagttgac ggcatccagc gacatcgaag aggcttttac atgggcatct
     1081 aagaacaacg acgtcgtgac tgtcgacagc tccggcaaca tcaccgccgt cggcgcgggc
     1141 actgcggacg taacagcgac cggcgattcc agcaaatctg tcggtacatg tgtggtcaca
     1201 gtgcgcgcag cgactcccgt aagcgtgact ccgtccaaga tggaacttaa catcggcgcg
     1261 accggcaagg cgaccgccaa gtatgacgcg aaagacagca taacttggga aagcagcgac
     1321 acagccgtcg ccaccgtcaa ggacggcacg gtaactgccg ttaaagccgg catcgccgtc
     1381 atcaccgcca atgggtcaaa aacctcggcc gcctgcacgg tgaccgtcac cgacccggcg
     1441 gcgcccgatc ccgtcacgcc tacgccggcc cccgtcgacg cggggactgt agataaagaa
     1501 aacaaccccg tcaataaaga agaaggcaaa ccggagaacg tagaggcggc gacgccggcc
     1561 attacggaag ctaccgagga aggtaaagcc gccgtagtta gcgcgacaaa gatcgaggaa
     1621 aagaacctcg tcgccaccgc cgacggcaaa ctcacgatca gccccgtgct tgccaagagc
     1681 gcgcttgaag aagtgatatc cgccgacgcg acagtcgcgc cgaagaacgt ggtcctgctt
     1741 ccgatcgtac aggctgcggt aacggcaaat aacgtggccg ccctcgcctt cacgatgacc
     1801 ggcgaacagt tgggcgctga ggaaaacaca gtcgcgggag acgtcaaggt gatcaaggtc
     1861 ctggcagacg gcaagggcgg acagttcagc tatgcctccg cggcggcaga ctacgcggac
     1921 aagactttca cgctcaaaga cgctgacggc aagagcctcg ccctgacgga taaggtcgcg
     1981 aaggcttcga cctatacgct ggtagtattc gtagccgaca acggcgactt cgacctcgac
     2041 gcgacggccg gcagcgtgat cgaccccgtg gcggtagcca ccaacgcggc gacagagccg
     2101 aaatccggcg gttcaagcag cggatgcaac ggcggcttcg gcgcgctggc attgcttgcg
     2161 ctcgcggtgc ttccctttat ccgccgcgaa aagagatagt acgattcgcg aaaaagtcaa
     2221 cacggcgtta atgacagtcc gataacataa atcagtaagg ccgccgccgg agagaaaccc
     2281 ctcctgcggc ggccttgtct tcccctttac atatttttgc gtcggcgtta ctttcgcgta
     2341 acttcggcga aaaacatccg taactttgtg gtggttaaat tgagtcaaca cattgagagg
     2401 atgatttttg atgatgaatt tgtcggatca gatcggaaag gcctggaagt tcgcgctgct
     2461 gctcatcgcc gtcacggcgg tattcacggc ggtcgcggcg cacgcggctg gtaaggagct
     2521 cgtcgtctat acggcgctgg agaacgagca gatcaataag tatctcgcta cctttaagga
     2581 agaaaatccc gatatcgacg taaaaatagt ccgtgactct acgggcatca tcacagcgaa
     2641 gctgctcgcc gaaggagcga ggacgccggc cgacgtcgtt tggggcacgg cggcctccag
     2701 ccttctcgtg cttgaaaaga agggacttat cgagccctac gctcccaagg ggctggcccg
     2761 tgtcgaaaag atgctgaagg acacggcgaa tccgcccgcg tgggtcggca tcgacgcttg
     2821 ggagtgcgcg atcgtcgtga ataccgcgga ggctaaagcc cagggactgc cggcgataaa
     2881 gtcatataag gacctgctgc gccccgaatt caagggcaag atcgtcatga gcaatcccaa
     2941 ttcatcggga accggttttc tcgccgtctc cggaatcctt cagctgatgg gcgagaaggc
     3001 gggcttcgac taccttgaca agctccatga gaatatcgcg ctctacactc actccggctc
     3061 cgcgcccgcg aagaaggccg cctctggcga gtttcccgtc ggaatctcct acggttacgc
     3121 cggcgtgaac cagaagaaga agggcgcgcc ggtggagata gtcttccccg ttgagggcag
     3181 cggctgggac gtcgaggcga acgccctgat caaaaagaag aatatcaagc cggaggcgaa
     3241 gaagttcctc gactgggcca tctccgacaa ggcgatcaac gcgctgaagg atgactacgc
     3301 gatcacggcg gtgaaggtga gcggcgctat ccccgagggg tattcaaaga gcccgctgtc
     3361 gcagctcgtg aagaagaacg acctgcgctg ggccgcccag aaccgcgacc gtctgcttaa
     3421 ggaatgggcc tcgcgttacg agggcaagac ggaagcgaag taggagcgta acgatgacca
     3481 ctctccgcgc gcggaatatt acaaagagat ttaagggcac gacggctctc gataaagtaa
     3541 gctttgagat ccgcgacgga gagttcgtct gcatattagg tccttcgggc tgcggcaaga
     3601 gcacgcttct gcgcgcgctc gccgggctgg aggccataga cgggggaacg atagagatcg
     3661 ggggccgcga cgtcacctgc gagcccccct ctgaaagaaa ttttgggata gtttttcagt
     3721 cttacgctct ctttccgaat ctcaacgtcg aggagaatat cgcctatggc ctctggaata
     3781 aggggcttgc gaaggatgag atcgcggcgc gcgtcgccgg gatcatcgaa atgacgggat
     3841 tgggcggcca caataaaaaa tatccgcagc agctctcggg cggccagcag cagcgggcgg
     3901 ccatctgccg ggcgctggta cttaacccgg agttcctgct tctcgacgag ccgctttcgg
     3961 cgctcgacgc gaaggtgcgc ctgcggctgc gccgggagat acgccgtata cagcagcgtt
     4021 tcgcgatcac cacgatcatg gtgacgcacg atcaggagga ggccctttcg atggcggacc
     4081 gtatcatcgt catgaacgag gggcgcatcg agcagatgga tacgccgcag gcgctttatg
     4141 acgcgcccgt caacggcttc gtcgccgatt tcgtcggcac ggctaacttt gtcggcgcgg
     4201 ggagggcgat ccgcccggag agcctctgtc tcagcaagtc gctgtcggac agcgcggtcc
     4261 aggccgaggt ctgtgacgtg gagtaccgcg gcgcctttta ccgcctcgag gtcgatacgc
     4321 acgtgggaca cctgatgata gacatcccct cgcagcagag tgacgccaga gtcctgcggc
     4381 tcggcagccg cctctatatc gatatcccgc aggataaggt catcatgctc aagagcgcct
     4441 gacgatgaaa aagatcaaaa acgccaaccg cttggaaagc gtgcttctca taataagttt
     4501 gtgcctgctt ttcacagccg tcgccgcgcc gatggctgtt ctttttgcga aggcctttac
     4561 cgattttgac ggggcctata tcggccttgc caattttcgc gaatattttg cttcgccgca
     4621 cctcgtcggc gcgctctgga actctctggc gatctccgcc gtcgtttcgc tgatatcgct
     4681 gctgctggcc tttatctacg cctacgcgct gacgcgcgcg gaggtgccgg cgaaggggtt
     4741 tttcaagttc atcgcgctgc tgccgctctg cgcgccgacc atgatgttcg gcatcgcgct
     4801 gatctacctg atcgggaata agggcgtgat cacgatgctg gggctgaagc tgccgctcta
     4861 cgggccgctt gggatcatcg tctccgaggt agtctacaca ttcccgcaag cctttctgat
     4921 cctctatatc acgctttcct ataccgataa ccgcctttac gaagcggcgc gcgcgatggg
     4981 gaccgccccg ctgcgcattt tgcggacggt cacgctgccg ggagcgaagt tcggccttgt
     5041 cagcgccttt ctcgtcgcct tcaccctctg tttctcagac ttcggcgcgc cgaaggtggt
     5101 cggcggcaat tacagcgtgc tggccaccga catctataaa caggtgatcg ggcagcagaa
     5161 tttcggcatg ggctcggtcg tcgggctgct gctgatgata ccggcggtgg tgatgttcgt
     5221 cacggagcgc ctcaccgcga gcgacaacgg cgtgacggtg agctcgcgca gcatggccta
     5281 ccgcgtgatc cctcatcgcg ggagggacgc ggcgctcacg ctcttctgcg ccctcgccgc
     5341 gggcttcatc ataacgctct tcgccgcggt gcttgccgcc tcgctgatca aggcctggcc
     5401 ctataatatg gttccgacct tcgagcattt cacggtggac agtcccgcca cgggagggct
     5461 gagctccttc ttcaacagcc tcgttaccgc gctgctgacg gcgttctgcg gcacggcctt
     5521 cgtctttatg aacgcctggc tggtggagaa gagcgcggcg aaccggctgc ttcggcaggc
     5581 cgaaaacctc ttttcactga taccgctcgc gctgccgggg ctttcgatcg ggctcgcctt
     5641 catcttcttt ttcaatatgg agggcaaccc gctgaatttc atctacggca cggcggcggt
     5701 gctggtgctg gccaacgtcg tccatttcta ttccgtgccc tacgtgaccg cctcctcggc
     5761 gctgaaaaaa cttgaccgcg agatcgaggc tgtcgccgcc tcgatggcgg tgccctctta
     5821 caggacgctc tttaaggtga ctatgccgat gtgccgcgcc gcgatcttcg agacggcgct
     5881 gtatttcttt gtcaacgcga tggtgacgat atctgcggtc gtctttctct atccgccgga
     5941 ttttaaactg gcctccgtgg ctatcgtgaa catggaggac gccggggaca tcgcgcccgc
     6001 cgcggcgctc tcggtgcttg tgatctttgt gaacgtggcg gcgaaactac tctacgaata
     6061 tacctttgtg atgaaaagga gcggcaaata atgaacaacg gcaaaaaaat caaatgtgtg
     6121 atcctcgact gggccggcac tacggtggat tttggctcga tggccccgct gcgggtcttc
     6181 tccgatatct ttgcacagcg cgggcttcgc cttgaaaccg acgagctgcg cgcgccgatg
     6241 gggatgccta agctggagca tatccgcgag ctgctcagga tggagcgtcc agcgaggcta
     6301 ttcagggaaa agtatgggcg tatgccgata gacgacgacg cgctggggat gtacgccgcc
     6361 tttgagccgg cgcttttgaa gatactccat gattttgcgg agccgctaga gggcgtctgc
     6421 ggcgcggtgc gcgagctccg tgaaacgggg gtaaagatcg gttcgaccac cggctatacg
     6481 aggaagatga tggatattat cgcgccgctc gcgaaggcgg ccggctatgc ccccgactgt
     6541 atcgtgacgc ccgacgaggc cgttgagggg cgcccagcgc cgtggatgat cttcaaaaat
     6601 atggaacggc tcggcgttta tccgccctct tcggtggtaa aggctgggga tacggcggcg
     6661 gatatccgcg agggcaaaaa cgccggcgtg atcagcgtcg gcatcctgcg cggcagcaat
     6721 gagcttggcc ttacgcggtc agagtttgaa tcgctgccgg ctaaggaggt agatgagagg
     6781 cggcaggccg cgcgcgagcg tttttatctc gcgggggccg actatgtgct ggagagcatt
     6841 cgggagctgc cggcctttgt aagggagatg gacaaagatg actgaaaaca aatatctgct
     6901 gctgacgccg ggaccgctga cgacgaccgc cgccgtgaaa gcggcgatgc tgcgcgactg
     6961 gtgtacgtgg gacagggact acaacgattt agtggaaaag ctgcgcggcg accttgtcga
     7021 aatggcgctg cgcgaccgcg cgaagcgcgc cggttatacc gcggtgctga tgcagggcag
     7081 cggcacattt gccgtggaat cggtgatcgg cagcgtcatc ccgcaggggg gcaagctcgc
     7141 cgtgctctcg aacggggcat atggcaggcg gatcgccgag atcgcgggaa tattgaaggt
     7201 accggccgtc gagctccgct ttgacgagtg cgaacgcccc gacgcggaga cgcttgccgt
     7261 gatgctggac gacgaccccg cggtgaccca tgtcgccgtc gttcattgcg agacgactac
     7321 cggtatcctg aacgacatcg agagtgtcgc ccgggccgcg aagagccgcg gcaaaaagct
     7381 catcgtcgac gcgatgagca gcttcggcgg tattccgcta ttcatggacg tgcttgagat
     7441 agattttctc ataagcagcg ccaacaaatg tatagagggg gtccccggat tcgcctttgt
     7501 tctcgcgaat cgcgccgctt tgtccgaatg cgccggactg gcgcgctcgc tgtcgcttga
     7561 cctttacgga cagtggaaga cgatggagga gcacggcggc aaatggcgct tcacctctcc
     7621 gacccacgtc gtctgcgcat tcgccgaggc gctgcgcgaa cttaaggcgg agggcggcgc
     7681 tgccgcgcgc aacaggcgct atgccgccaa cagggatatg cttgtccgcg ggatggaggg
     7741 cctcggcttt aaggcgctgc tccccgcgga gctgcgttcg ccggtgatca cctctttcct
     7801 ctatccagac gggatcggct ttgactttgc ggagttctat gaatctctca agcgtgatgg
     7861 ctatgtgatc tatccgggaa aactctccga acgcgacacc ttccgcatcg ggaacatcgg
     7921 cgacatcaga gaaaaacaga taaccgggct tctggccgcc gtggaaaggt atgtcaagcg
     7981 atcggaagcc cggcctctat gcgcctgatc gatccggcaa ggataaggtc tggccgctga
     8041 cttgaaaatt ttgtgatcgg cccctcggat tagagccgcc gtatttggtg atgacggcgg
     8101 cgcagacgat ccgcccgtcc ggcccgttgc gggccgcctt cgacatcagc cataatgatg
     8161 cacggttagg agtcgtcctc gccggtttcc acatcggcga gttctttcag ttcccgcagt
     8221 ttctcggtta aaatattctt attcggcaga tgcagctgat aatcagccac gagcgtgggc
     8281 gacaggcttc tgctcaaagc gtactctacg accatatcgt cttttccggc gcataggatt
     8341 aagccgacgc tgggattttc gctcggcttc ttgacgtcgc ggtcgagagc ttcaaggtag
     8401 aattccaact gtccgagatg ctccggcttg aagtccgtta ccttaagttc aatcgctaca
     8461 aggcaagata gttcacgatt gtagaaaagg agatcaatat ggaagtcttt gttgccgacc
     8521 tgaacaagat attcttcgcc gacaaacgtg aaatccttgc caaactctaa gatgaagtcg
     8581 cgaatgttcg ccacaatgga ttttcgaagc tctttttctt tgtggttctc cggcacgtta
     8641 aggaattcca agacatagct gtcacgtagt gctgtgaggc cagtgttttt ggcaagaaaa
     8701 agtttatttc gctcatctga aaacaaagtg cgttcaaaga gcatactgtc aatctgccgc
     8761 tccagttctc gcttggtata attgttccgg ccgcagagaa gcagatagaa ctcccgcgct
     8821 tcatcggtct ttgcccgtga cattattatc aggttctgcg tccagctgat ttctcgcgcc
     8881 aatggtgcga gtttttcgct gccactgtac gtttcgtaaa attggcgcat gcgccagatg
     8941 ttcgatgcag aaaagccctt gatgtccgga cgttctgatt ccatgaatcg ggcgaagtct
     9001 gtgacaatgg atttgcccca gccgccgttt ttaaccttgt tgctgacata ggcgccgatc
     9061 tcccagtaca tagaaattaa ctctcggttc acggctcgaa aggcgttctc acgggagcgt
     9121 tcaatgatgg atataatctc accatacgcg gcatggttgt tatgtattag ttgactgctc
     9181 atggttccgt tacagcccct ctttttttcg caagcgaagt ctcgtgtgaa ttctcgcact
     9241 gctgatgcga gtttttgaaa acagacatct cggcacacat cacttgtatt gcatgatttt
     9301 attgcgagta gggcctacgg ataaaaatcg gaccaagcta agctgcataa ataggtgtag
     9361 gctccgatag tctttcgggc taagataacc caaagtgctc ttgattcact tttttattat
     9421 accacctaat ataatcatcg atgtacttga tgaactttcc agtcagggca aacgcatcaa
     9481 gaaagtcagg taaatggtaa actgcgattt agcgcatttc catcgctccg gcctccgagc
     9541 cggggccgag tggcgttggt ttttgcttta caattgatgt tggaacaaac ctgaagccac
     9601 tggatgccgg gtcaagcccg gcatgacaag ataaacctcc gtttacctta ccggttcgta
     9661 atctatccgc gagtcttcgt cggtggcttc aagtttgaag atgacggggc gcaggccgtc
     9721 gttgcagctg cagatcgcga cgccgggttt tctgatccag tcgccgtaat agaacaggcc
     9781 gtttccggag ccgtgcgcga gcgcgaaaac gtattggtat atcgccttcc acgcctcgtc
     9841 gcagaagccc tccggcttcg cgtagtcggc gtggaacgtc tgtccctcgc gcagcatcgg
     9901 gcaggggccg agtccttccg cgccatactc ttcggcgagc tctttgtcca aagtggtctt
     9961 taagacggtg atttttacct ttttcataac ttgtccgctc ctatccgcag taagctaaca
    10021 gcatctcgcg cagcgtcttg caggccagcg cggtcgaagc gccagagttg tcgtagtgcg
    10081 gcgaaagctc gcagaggtcg aaggctttga cgttcaggcc gcgcagggcc agcagcgctt
    10141 tcagcagctc tgcgaagcgc aggccgcctg cctcgggcgt gccggtgccg ggaaactccg
    10201 ctgggtctgt gacgtcgagg tctagcgtga tatagaccgg cgcttcgccg atctctttta
    10261 cggccgcgcc aacggtctcg gcgcggaatt tttccatcgt cgtgcgcccc gcgctccacc
    10321 gcatctcttc gcggctgccg gagcggatgc cgaactggaa tatcctgccg tcaccgagga
    10381 tgtcgtggca gcggcggatc accgaggcgt gcgataggct ttctcccatg taatcactgc
    10441 ggaggtcggc atgagcgtca aagtggataa ggcgcaggcc gggatatttt tttgccgccg
    10501 cgcgcaccgc gccgagcgta acgagatgtt cgcctcccag cagcaccggc gttttgccgt
    10561 cggcgagtat ctccgcggcg gcggcctcta tcgcctctat cgccgcggcg gcgttgccga
    10621 agggcaggtc gaggtctccc gcgtcaaata cgccgagatc ctcaagatct ctgtcctgat
    10681 aggggctgta ggtctcgatc ccgaaggatt cggagcgcat cgcggcgggg ccgaagcgcg
    10741 tgcccggacg gaaggaggtc gtcgagtcga agggcgcgcc gaagaggacg gcgcgcgcct
    10801 ccgcgtaggg cgaggaacag ccgatgaatc cctgaatgtt cgtttccatc tagtctttca
    10861 gctcaagcgc ctgtttcacg tagttgggca gcatgaaggc gccgacgtgc aagtcggtgt
    10921 tgtagtatct cgtctccagg ccgaggccgt tccaggcggc ggcgtcaagg tctttgatcg
    10981 ggtcgaattt ctttgaggcg aacccgaaga gccagtgtcc ggaagggtat gtcggaatat
    11041 gggcctgata gacgcggcag acggggaaga aatcctctat cctctggtgc gcgcgcttca
    11101 ttgaggcgcg gtaggagtcg taatagggat tctcatgctg gttgacgagg atgccgtcat
    11161 ccgtcagcgc cttgaagcag ttgccgtaga attcctttgt gaagagtcct tcgccggggc
    11221 cgaaggggtc tgtcgaatcg acgatgataa ggtcgtattt ttcgctggcg gtgcgcacga
    11281 atttgaggcc gtcctcaaaa tagagcgtga cgcgcgggtc gccaagcttg cgggatgtga
    11341 agggcagcag ctcgcggcag accttcacga ccatttcgtc gatatccacc atgtctatct
    11401 tttcgatggt tttgtagcgc gtcagctcgc gcaccgtgcc gccgtcgccg ccgccgatga
    11461 cgaggacgcg cctgacgtcc gggtttgtcg ccatcgggac gtgtacgatc atgtcgtggt
    11521 agataaattc gtccttctcg gtgagcatca tcaggccgtc aagggtgaag aaacgcccga
    11581 actcctccga atcaaagacg tctatctgct gaaaggggct cttgccgccg aagagctgct
    11641 tttttacctt tattgaaaaa cgcaccgtcg gcgtatgttc ttccgtgtac catagctcca
    11701 tgattatctt cctcctattt tacgatgtat agatcgttta actccatatc ctgcggcccc
    11761 atgacgaggc tgcctttttt cttcgcgtaa aggatgtagt cgagcgcctc ccgcgttacc
    11821 tcctcgcctg gcgccagtat cgggatgccg ggcggatagc acatgacgaa ctccgcggat
    11881 atctttccca ccgcctcccg aatcggcagc ggcctgcttg gcgcgtaaaa ggcctcctgc
    11941 ggcgtcatgc gcaccacagg agggatatat tcgtgatcga gcagatgaag cccctcgcgc
    12001 ccccgcaggc gttttatttc cgagagcgag gcgacgaggc gctctatcgc gtaatggttg
    12061 tcgccgacgg agatgatcgc gagcatattg cccatgtctc cgaactctat ctgtatcccg
    12121 tagtcgtcgc gcagcagatc atagacctcc acgcccgcga ggccgatctt cagcgtattg
    12181 acggagagct tcgtcgtgtc gaagccgcag atgtacttgc cgtcgattat ctcgcgtgag
    12241 aaggcgtaat agccgccgat tttgtttatc tcgccgcgcg cgtattcggc gagcgagacg
    12301 acgcgggaga aggtctcctt tccctcggtc gcgagcgcct tgcgcgcaat gtcgagcgaa
    12361 ctcatgagaa gataggaggc gctggtcgtc tgcgtgaggt tgatcaccgt gcgcacgtaa
    12421 tcgggacgca cacgccctcg tttcatgagc agcagcgaac tctgcgtcag cgagccgcct
    12481 gtcttgtgca tgctgaccgc cgccatgtcg gctcccgcct ccatcgccgt cagcggcata
    12541 tctgaggcga agtagaagtg cgtgccgtgg gcctcgtcga cgagcgccgc cattcccgcg
    12601 cggtgcgccg cttcggttat gcgcccgagg tcggcgcaga tgccgtaata ggtggggttg
    12661 ttgacgaaga cggcctttgc ctcgggatga gcggcgatcg ccgcttcgac gtcatccgcg
    12721 cacataccga gcgaaatgcc gagttcggga tggatgccgg ggtccacata tatcggcgcg
    12781 atgccgcaga ggatcagcgc gttgatcgcc gacttatgga cgtttcgcgg aatgattatc
    12841 gaatcgccgc gtttgcagac gctcatgatc atcgcctgta cggcggcggt ggtgccgccg
    12901 attatcagaa aggcgtcgtc cgccccgaag gcgtcggcgg ccagcgcctc cgcctctttg
    12961 atgacggagg tcgggtggct taggttgtcg agcggcttca ttgaatttac gtcgacggag
    13021 aggcaggcct tgccgagaaa ttccgtcagc tccggcgttc cccggccctg tttgtgtccg
    13081 ggaacgtcaa aggggacgac gcggctcttg cggtactcgg cgagcgcctc cagcaaagga
    13141 gccctctcct gcgccagttt gtatgttctc tctttcatcg cggccactta atacatattc
    13201 atcccgtagt agatctcgag catctctttc gtgatacggt cggttatcga gagacgctcc
    13261 tcgggaggca gttcgcgtgg atcgatgttg aagaggtagt cggcgagccg tatctccttc
    13321 agcatcatct tcgtatggaa tatgttcgac tgatagacgt tgacgtctat cgcgtcatag
    13381 cggcgcagcg tagcttcgtc gatgtagttc tggatggaat ttatctcatg gtccttgtaa
    13441 tacttcttcc cgtcgatgtc gcgcgtgaag ccgcggatgc ggtaatccag cgcgatgatg
    13501 tcggagtcga actggccgat gaggtagttg agcgcgttca gcggcgatat ctttccgcag
    13561 gtggagacgt cgatatcgac tctgaatgag cttatatcat tgtttggatg aaattcgggg
    13621 taggtatgca cggtcacgtg gctcttgtcg agatgggcga cgacggtctc gcgttcctcg
    13681 ttgatctttt ccgcccaacg gcccatattg catgattcgt cgatctgcgc cggcggcacc
    13741 gattcctcgg agatgaggat ggtgacgctc gctccctgcg ggtcgtaatc ctgcttggag
    13801 atgttcagca cgcaggcgcc gatgatatcc gtgacgccgc ataatatctt agtaagccgt
    13861 tccgaattat actgctcgtc gatataagcg atataatcct gcttttcccg gtctgtcttt
    13921 gcaaaacaga tgtcgtaaat gttgaaactc aacgtctttg tcaggttgtt gaatccatag
    13981 agctggatct tgtctttcaa ccctatcccc acgtcccttc tcaagcccga ggctttatat
    14041 ttttcttgcg ccgaaatttt gcgcggttaa agggaaacta tacatataaa gcgccgcgtt
    14101 gtcaaaggtt tatgcaaacg attgcttaat gatttcgcac aaaaaaatgt ccgcggagca
    14161 aggggggcgg cgtctgtcct gcgatgcgga aagggccgga gggccgcggg tgaaatggca
    14221 gaattgaata gccgtttttg agaagaattc aaagaaatga tatgctattc ttgcgttgag
    14281 gcgtagatca tgccctctaa atgacgaaac atgtgaataa aatcgaggtg gaaattatgt
    14341 ctttgaaaga tgcggcaaat ttatacttta atcccggctg cgcgttgagc atctatcggc
    14401 cggaaaacgt aaaaacaata tttgattatc tgcttaaaaa cttccctgaa atagagatgc
    14461 acgatatctg ctgccgccat gatcccaagc tgccgggcgg ttcggtgatt atcaatgtgt
    14521 gcgccggatg cggcaaacga ttcggttccc tttatgacgg cgtctcaacg atttcgctgt
    14581 gggaagtcat ccgggagctg gataattttc cgttcccgga ttataagggg atggaagtca
    14641 gcattcacga tccctgcccc gtgcgaaacg agcctggcgt acacgaggcg gtcagagcca
    14701 ttttgaaaaa aatgaagatt agaatcgtcg aagcggaaaa tatcggcacg aactcagttt
    14761 gctgcgggga tagtttatac ccgagctgtg ataaggagaa aatcttggct gcgatgaaaa
    14821 ggcgagctga cagtatgcct tgtgaaaacg ttgcggttta ttgcgtctcc tgcgtcaagg
    14881 ccatgcacat aggcgggaag gtcccgcgcc atttggtcga tcttcttctg ggaaaagcga
    14941 ccgacccgca ggaatgtgat attgagcgct ggcataataa gctggacgcg tatattcaaa
    15001 cgcattaacc gacatggaga aaggggccgg caaatgactg aggatgagat gtatgaagct
    15061 gtgataacga acgacgccaa ttatgacggg tcgtttttct atggcgtgaa atccacaggc
    15121 atattttgcc ggccctcctg tcaatccaag aaaccgctgc gggaaaatgt atgttttttt
    15181 catagcgccg gcgaagcaat gaaagaaggt ttccgcccgt gcaagcgatg caggagcgac
    15241 cttctgtctt acagaccgat ggagaagatc gccgggctgg tgaagaaaca tcttgacgag
    15301 ctatacgagc gtcagacctc atggaacggc gaactgcgtg agataggact ttccgagcgg
    15361 cgggtggtgc agatattcaa agatgtttat gggatgaccc cgaaggcata tatggatatt
    15421 ctcaaattgc gggaggcgaa gcggctttta tccgagacag ataaaaaggt gattgatatc
    15481 gcagcgtctg taggttttgg cgggctgtcc gcctttaatc gttttttcaa agaacaggca
    15541 ggatgcagcc ccgccgcata tcgaaaaatg tataagaagc aggcataaca ccgccgaggg
    15601 gcggcatttc catttaggaa catgagacaa aaagcggcat ggccctaaag ccatgccgca
    15661 gatgtaacct ggtattactg cttttttgcg agcgttgccc ggcctatttg ccgctgaact
    15721 tgatcttctg gtacttttca gggactttga cgtcggtggc tttcatgtag cccttgccga
    15781 ggatgtaggt atcctggtag atgagcatca tgttcttctt cgtgacgccg gttccgaggt
    15841 cagtgtagtt ctgaccgttc catttcgcgc cgggggtgaa ctccgcgtag caggcgagga
    15901 ggtctttctt gctgttaagc ttcgccttgc catcgactat acgcttgccg aattcggcaa
    15961 gggcggcgct gttcgtgtaa ccgtaggagt aggcccatgt acccatgcgg ccctttgcgc
    16021 ctgaatctga taccgtcttt tcaaccttct tgaggatgac gggccagttg ccggcttcct
    16081 tcgtgaggtc gatgccgaac gctccggggt agcccatcag cggcgagggg aggtcagctt
    16141 cgatgaagta tccgccgtat ttggcgagct gtttgagaag aggctcggtg tgggcgtcgt
    16201 tggtgcagaa gaaggctgtg ttcttgccat acttcttgac ccatgccggc gtcttttcaa
    16261 ggatgaactg ctgggctccg gccacgccta cgtcgctcgt ggggtcgggg gccgtttcaa
    16321 atacaaattt gatgccgagg tctttgcagg cttgctccat gatcgcgcgg cggcgtccga
    16381 gcgtctcgta gctcatgtgg cgcgggaagg agatgtgtac gaaggtcttg catccgagct
    16441 tcttcgcggt atcgatgatg aggtatccgc gtgagacgaa gtcggcgttg atcgccatgt
    16501 cggcgactga ggtgatgacg ttcgggtctt cgtgggcctc gccggcgaag cagaggatgt
    16561 ccttcctctt ctccttgacg cggcggaaag cttcagcggt tcccgggatc gcctggttga
    16621 cgacgatgac cttcatcttg gggtcgtcgg cgagtccggc aatctgggag atcgtcgtct
    16681 ccatctccga catgaagttg tcgggatagg tgagatgctg gatcatgccg cccttggcca
    16741 catctccgta tttcttgatc atcagctctg ctccgcggag gtcgtcttca ctctgtgata
    16801 ctgtcccggt cactattccg atatggaacg gcgcctcggc tgccatagcg gcggtgctta
    16861 caaagagcgc aagcaacgca gcaaacaata aaagcatagc ttttttcata aggattcctc
    16921 ctaaattttt ttgccgcatc tcgaaactgt atacttattt tttacgtaaa caatctcagg
    16981 gaggcgcgca tctgccatag cagacagccg gattatagtc tacctttatt tgggctgtca
    17041 ataaaaaaag cgccttatat atcagttgca tttaatatat aattaattaa aatagtaaat
    17101 tcttaagctg cgtgaccaga attttcagtg cttgacatat tctgtccgtg gtttaatata
    17161 gagaagctaa attaataaat gccgttgcgg ggggcggggt gtgacgtttt ttagcagttc
    17221 aatatatcag tattttgtgc agataaaata agtaaaaatt acattcataa attcataaaa
    17281 ttgaatataa ggccgctgaa aaatatcctt acaggaggca gttgtccata tgataaagaa
    17341 aaaaagagtc gaacgtctgg cgcagacatt gaaggatagg gggatcgatg cgctttatat
    17401 cggtccttcc acggatctgg aatatgtcgg agggcttgac acccagccgg atgagcgcgt
    17461 acgcggcctg atggtcgcta aagacgcgcg ctgttttgcg atgacacccc tgctttataa
    17521 agaagagatc gtcaaggctt tcgaagatgt tcccttttac gccgagtgga acgaccatga
    17581 gggcttcacg ggagcttttc gccgcggctg tgagcacctg ggcatcgtcg gcggcaggat
    17641 agcttttaac gacggcgtgc gcgcggtgga catgcttgcc gtacgcgacg cgatgccgat
    17701 ggagatggtg aacggagctg acctgctcgc cggacaacgt tcccggaagg atgaggaaga
    17761 gcttgaggtg ctgcgcgaat cgtcgcgcat agtcgacaaa gtggtagcga aactccagaa
    17821 gttcatccgt cccggcatca aagaacgcga cgtggcgaag aagatccccg agttctttga
    17881 ggaagagggc gtcacccaga tgtccttcaa cccgatcgtc gcaagcggcc ccaacggctc
    17941 gatgccgcac tattcggggg gagagcgcgt catcggtgag aacgacatcg tcatcctcga
    18001 ccttggcgga aggtataaga gctactgttc cgacacgacc cgcacgcttt ttaccggcac
    18061 gcctacggaa gagatgaaaa aggtatacga gatcgtgaag aggtcgcagg cagccggcga
    18121 ggccgccgtg aggcccggcg cgacgggcca ggacgtcgac cgcgcggcgc gccaggtcat
    18181 tatcgacgcg gggtacggcg aatttttctt caaccgcgtg ggacacggag taggcctggc
    18241 agtccatgag agcccttata tgatagaggg caacgacgtt ccgctcgcgc ccggcaatgt
    18301 attcagcgtc gaaccgggga tataccttcc cggcaagttc ggcgtcagga tcgaaaacct
    18361 ggtcgcggtg cgtcccgacg gcagcggcga ggcgctgaac cactttacca gagagctgac
    18421 gatctgcgga gactgatttg ctgaaagaca cggaagcgga tttttatgat cctccttccg
    18481 tgttttccat ataagtacca aatacgcact gaatttaagg aggaatgatt caacatgaga
    18541 agagcaacag tctttctttt tgcgctgatc gccgcgtcat ttatggcgac ggcggccttt
    18601 gccgcgccgg cctttcacat cggagtcgcg acgctgaccg tttcccaggc cgaagacacc
    18661 taccgcggcg ccgaacgcct gatcaaggaa tacggcgacg tggctaacgg cggcatgatc
    18721 aagcatgtca cgatgcctga caacttcatg tcggagatgg agacgacgat ctcccagata
    18781 gtcggactcg ccgacgaccc caagatgaag gtcatcgtag tcgacgacgc gatccccgga
    18841 acgacggagg ccttccgccg cgtcaaggag aagaggaagg acatcctctg cttcgccgga
    18901 gaaccgcagg aggacccgaa cgtgatcacg agcaccgcgg acttcgcggt cggcgtggac
    18961 aacatcatgc gcggctacct catcatcaac accgcaaaga agcttggagc taagaccttc
    19021 gtgcacatct ccttcccgcg ccacatgagc tacgagctgc tttcacgccg ccgcgcgatc
    19081 atggagcagg cctgcaagga tctcggcatg aagtttgcct ttgagacggc ccccgacccc
    19141 acgagcgacg taggcgtggc cggagcgcag cagttcatcc ttgaaaaggt cccggcgtgg
    19201 gtacagaagt acggcaagga ttcggctttc ttctgcacca acgacgcgca gacggagccg
    19261 ctcctcaagc aggtcgccaa atacggcgcg atctttgtcg agccagacct tccctcgccg
    19321 ctgatgggct atcccggagc gttcggcatc gacctcaaga aagaggccgg aaactggccc
    19381 gcgatcatga agaaggttga aaagacggtc gtggcttccg gaggcaaggg acgcatggga
    19441 acatggccct attcctacgg atggagcacg gtctgcgccc tcgccgaata cggtaagcgc
    19501 ataaccgaag gcagcgcgaa gctttacaac cttaaagacc tctggaagtg ctatgacaaa
    19561 tacactcccg gcgcggaatg gaacggcgcg ccttactatg atatggcgaa acagatgaag
    19621 ataaagaaat ttgttctcgt ctacgaggat acctatgtat tcggacgcgg ttacatgggc
    19681 gtgaccaagg aaaaggttcc cgagaaatac atcaaactta agtaacacgc agtgtaatgt
    19741 cacgtaaagt ttttccggcg cgaagcgccg gaaaaacttt tgtggtacaa cggcatactc
    19801 ccgacggcag ttttttcttg aatttttacg taaaaaacac taagatgcat tgcgtgtcgt
    19861 ccattaaagt gaggcggcgg cgatatattt gggaaaatat aagaggtgaa atatatgtcc
    19921 atggaaattc cccttttgaa gatggagaac atcggcaaag aatattttgg caaccgagtt
    19981 cttcaggatg taacgttttc actgcggccc ggagagataa tggggctggt aggagaaaat
    20041 ggcgctggaa aatcgacctt gatgaatatc ctcttcggga tgccggtcat tcaggagacg
    20101 ggtgggtatg aggggaaaat tatgatcgac gggcaggagg tccgtttcaa ggaccctctt
    20161 gacgcgcttg aagccggcat cggaatggtc catcaggaat tttccctgat cccgggcttt
    20221 acggccacgg aaaatatact tttgaacagg gaatcggtaa agtacaacgc gctggtcgag
    20281 gtattcggag agagactgat gacgctcgac aggccggaga tgagggagag ggccgaaaag
    20341 gcgataaaaa cgctcggcgt ggaactcagc ccggagacgc tgatcagcga gatgccggtc
    20401 ggccacaagc agtttaccga aatagcgcgc gagatcgaca gaagcaaaac gaggcttctc
    20461 gtccttgacg agccgacggc ggtccttgcc gaaagcgagg cgaccgtcct catctcggct
    20521 ctcaaaacac tttccaaaca gggtatcgcg ataatattca tatcgcatcg gcttcaggag
    20581 atcatcgacc tctgcgacaa gctcatcgtc cttcgtgacg ggcgcgtcat acaggaggcc
    20641 tgcacgaagg agaccaacgt ccgccagatc gccgcctgga tggtagacag aaagggcgat
    20701 aaggccggcg aggagaaggc tgagaaaaag gagaaaacga tcggcgacgt catactgcgt
    20761 acggaacatc tctgggtcga catgccggga gagacggtgc gcgacgtttc gatagaggtc
    20821 cgtcagggcg agattctcgg tttcggcggt ttggccggac aggggaaggt cggcatttca
    20881 aacggcatca tgggacttta cgccgcgggc ggcaaggtct tcctgcgcgg aaaagagata
    20941 aaactcaacg accccgacgc ctctctgaaa gaggggatgg ccttcgtctc tgaagaccgc
    21001 agaggcgtag ggcttctgct tgaagagggg atagattgga atataacctt caccgcgatg
    21061 caggtgcagg agaagtttat tagaaagctg gccggaggcc ttgtcaaatg gcgcgacgac
    21121 aaggcgatcg aggagtgcac gagggaatat ataaaatccc ttgagatacg ctgcaccggc
    21181 cccgcccagc gcgcgataga gctttcaggg ggaaaccagc agaaggtctg tctcgcgaag
    21241 gccttcgcgg tgagcccgga gatacttttt gtctccgagc cgacgcgcgg catcgacgta
    21301 ggcgcgaaaa agctcgttct cgatacgctg cgccgcgtca acgaagagga cggaacgacg
    21361 atcatcatga cctcctccga gctggaggag ctccgttcca tctgtgaccg catagtgata
    21421 ataaacgaag gcagggtctc cggcatcctg ccggcgtcgg cgccggcaga agagttcgga
    21481 ctgctgatgc ttggccacgt cgaagaacca gccgccgtaa attgataaag ggaacgcagg
    21541 tgagcaaaaa atgaagaata aattacagga atttattgag aacgcaggat ggccgcgagt
    21601 aataatcgcc ctcttcctgt gcgcgctctt cgtcgccgcg ccgtttgtcg gcgtgcggat
    21661 cgacgcctcg ctctccgaca cgctcgttcg tgtcggaatg aacggcatac tcgtcctcgc
    21721 gatggtcccg atggtacagt cgggatgcgg gctgaacttc ggactgccgc tcggcatcat
    21781 cgccggcctc ctcggagccg tcacctcgat acagatcggc ataaggggca gcgtcggttt
    21841 cctcctcgcc gcggcgatcg ccattccgat agccgtcgta ctcggctggc tgtacggaca
    21901 gctgctgaac cgcgtcaagg gagacgaaat gatgatcgcc acctacgttg gattctcatc
    21961 cgtcgccctc atgtgcatcg cctggctgct gctcccatat acgagcccga cgatgatctg
    22021 gggctacggc ggttctgggc tccgcacgac gataagcgtc gagggctatt ggctaaacgc
    22081 gctgagcaag tatgtgaata tccagatagg cgaatttttc tatgtgccgg tggggatgtt
    22141 cctcttcttc gccttcgtgg ccttcctcgt atgggccttc ttccggacga agatcggaac
    22201 ggcggtcacc gccgtcggtt ccaatcctga attcgcgcgt gcatccggca tcgacgtaga
    22261 ccgtatgcgc acgatctccg tcatcctttc gacggtgctt ggagcggtcg gcatactggt
    22321 ttacgaacag agcttcggat tcatccagct ttacatgggg ccgttctata tggctttccc
    22381 cgccgtcgcc gcgatcctgc ttggcggcgc ctccgtcaat aaggccacga tggtcaacgt
    22441 cgtcgtcggg accttcctgt tccaaggaat actgacaatg acgccttcgg taatcaacag
    22501 cgtcatgcag acggacatgt ctgaggtcat ccgcatcatc gtcagtaacg gcatgatcct
    22561 ctatgccctt acgcggaaag tgacggtgaa acgctaatgg ctaaaagaaa tcgtgaattg
    22621 aaaagtatgc tggccgacta cgcggtcccg atcgtcttta tcgggctctc cgcgatagcc
    22681 atcccgcttt caggcttttc cgccacatat ctgatacagg agatgttcac gcgcctggcg
    22741 agaaactcct tcctcgtcct ctcccttctc atcccgatac ttgccggcat gggactcaac
    22801 ttcggcatgg tcctcggcgc gatggcgggg cagattgggc tcatattcgt cactgactgg
    22861 gccgtcgttg gctgggaggg aatgctgctg gcctcgatcg tgggcatgcc gatcgcgatc
    22921 ctgctcggat atatatgcgg cgccgtcctc aaccgcgcca aaggccgcga aatggtgacg
    22981 tcgtatatcc ttgggttttt catcaatggc gtctatcagc tgatcgtgct ctacgggatg
    23041 ggcaacatcc tgccgatatc gaacccgcag ctggtgcttt cgcgcggata tggcatacgc
    23101 aacgcgataa acctcacggg cgtccgccat gttctcgaca acctcatccc gtttaagatc
    23161 ggcacgatcg acgtaccggt ggcgaccttc atcctgatcg gcatcttctg cctcttcatc
    23221 gtctggttcc gccgcacgaa gctcgggcag gacatgcgcg cgctcgggca ggatatggcg
    23281 gtcgccgaat cggcaggtat ccccgtggaa cgcacgagga tcatcgcgat cgtgatctcc
    23341 acggtgctgg cctgcttcgg acagataata ttcctgcaga acatcggcac gatgaacacc
    23401 tacaacagcc acgaccaggc gggaatgttc gccatcgccg cgatcctcat aggcggagca
    23461 tccgtcagcc gcgcgacgat caccaacgtc tttgtcggcg tcgtgctctt ccacctgatg
    23521 ttcgtcgtct ccccgatggc cggcaaggag cttatcgggc aggcgcagct tggggaatac
    23581 ttccgcgtct tcgtctccta cggcatcatc gccctggccc tcgtgcttca cgcctggagg
    23641 cgccagaggg ataagatcga ggccagaagg agcctgagag gagaatagcc atgacgcaca
    23701 atataaataa aaagaggctg atcatacgtc tcgcgctcgt cgcgcttctg gttctcctat
    23761 gctttgtcct ctactatgtc ggcaaagagc acgaggtgct tatcgacaat aagacggccg
    23821 ccatcgacgg acacgagtat caggagatag cctatatgaa cgtggtcgtt gacggcgacg
    23881 aggataaggc gatggagttc tacgcgggcg accgtgacgt cgtaaagctt aagggaccga
    23941 gccacaggat caagataacg gtcatcaacg aggacaccga agaggtcatc aaaacggtag
//
