LOCUS       c00008_NZ_QIBX..       15923 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_QIBX01000008.1 Slackia equolifaciens strain DSM 24851
            DSM24851T_contig_008, whole genome shotgun sequence.
ACCESSION   NZ_QIBX01000008
VERSION     NZ_QIBX01000008
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:13:30
            Original ID  :: NZ_QIBX01000008.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 94051
            Orig. end    :: 109974
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15923
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[104051:109643]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15592
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..15923
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15923
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2398..3006)
                     /locus_tag="ctg8_82"
                     /transl_table=11
                     /translation="MSTTQAHDSQYHGDADVREVLFTEDAIVQRVRELGEQITEDYRDA
                     AYEPTPHGDPALLVVSVLRGAAIYMSDLVRAIDLPLEMDYMAVSSYGTGSKSSGVVRII
                     KDLTSNVEGRHVLIAEDILDSGLTLKYLLRVLESRNPASIQVATLLRKRNPQQAEIECK
                     YIGFECPDEFIVGYGLDFAERYRNLPYIGVLKPEVYQGR"
     CDS             complement(3441..4010)
                     /locus_tag="ctg8_83"
                     /transl_table=11
                     /translation="MADATTNTNPEQPTPQTASAPVQEQPAAAQAQPAAASVQQQPVTT
                     NPVPLAGFAPAAGQVPPAGNVPPTGQVPPAGQVPPQQPFGPAPAVPPQPMPQNMPGMPL
                     LYLTGGMKFGWAALGFFLGPLAILVAWLTNAHNFPQAKSEAVKFSLIGFLVSIVGWILL
                     LMLFGFTACAAIGAAATGASSAVYYF"
     CDS             complement(4337..5632)
                     /locus_tag="ctg8_84"
                     /transl_table=11
                     /translation="VAVILALVVGAGAAAAVFLGGINSKLQQGVDDNLLNQLTVTESSE
                     PFYVLLMGVDGSSERENSEQYAGDTFRSDSIILARIDPQQKQVTLVSIMRDTYVDMGEN
                     GYQKINAAHAIGGPAYAVEVVSEYAGVPISHYAEINFDGFKEAVDSLGGIEVNVPRDID
                     DPQAGGSLEAGEQTLNGDQALILCRSRHSYDDQGDGDTYRAANQRLVIGAIAKKLLASD
                     PATMASVVNSMADYITTDMSVDEIVSIALQMQGMDTDSGIYSCMNPTVSAYENGVWIEY
                     TNVEAWKAMMTRVDQGLSPTVNEEDSANRGGVTDGTLDKEYIAQSALADSGNTGSLASE
                     NAVAVRNGNGVSGVAATASSVLTNSGYDVTETGDADNYDYASTLIVYNDSSMESEARSI
                     GEALGVGTTMLNDGSYTFDGNFLVILGADYTG"
     CDS             complement(6035..7396)
                     /locus_tag="ctg8_85"
                     /transl_table=11
                     /translation="MNKRDNKHYGQMPSTVRPVSYGGSRHASGRTPKTNALPPATGATG
                     AAAYSRANYTSKKKRSKGLIALLVVMIVALLFGGVAFGGYLYLNSISNQMHEGVDEELE
                     AVLTPEEEVQPDEPFYMLVMGIDKSEERANRAEFAGDTFRSDSMILTRVDPQQKTVTLV
                     SIERDTYVDIEGYGPNKINAAAAYGGAALTVKTIEKFAGVDISHYVAIDFDGFKEAVDA
                     LGGIEVDVPMTIDDPQAGGRVEAGEQTLNGDQALILCRSRHAYDDYGSGDYYRMANQRM
                     VMGAIAKKLLASDPVTMANTISSMADYITTDFNVEEIVSIATQMQGMDTENDIYSAMNP
                     TVSQLIDGIYYEICNTEEWQDMMSRVDQGLPPYKDEDRNKNDGGGLDGTVTGVQEYGAE
                     NADLSDSAAAALEDSLSESADATESSGESSGATDETYYDDAYYDDASYYEEGYY"
     CDS             7681..9252
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_deac_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_86"
                     /sec_met_domain="Polysacc_deac_1 (E-value: 1.5e-29,
                     bitscore: 95.0, seeds: 80, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTSRSGNHPSGRPSVAGKRTVHGSGSASKYSRDSYVGRRSSSPS
                     ARRTIGGSSVAHDADDAARMAGGTGRQGAIADASDTGRYSVAPDPSSTGRYAADRYAGR
                     SSSGRPSVRSGRTNTRRSGTSYEPLFDESADGIGRSIRRRRALTRGVIALAAIAVAIGG
                     VVFFMSNAPITVSVNGNSIDLSGAKTVQAAFEAAGEPAKAGNLVDVEGATLEEGKGYQF
                     SFAVNGQPGTDPTSPLKEGDAVVFSDGGDIEEESDSTDEPIPHETVDQGYGPIHMVDNP
                     GADGVKTTKTGKISGKTVTQTTAEPQDRVYRRYYPDTGEDKVVALTFDDGPWDTSTAEI
                     LDILKANDAKATFFTVGNRIDDSTADLIKREVAEGHQVCTHTWDHAAGSGQGVNLSFMS
                     KDEQREEITKGMKAISDVTGQEASKVIRSPGGNFPTEVWMNVEDLITAEIGWDIDTEDW
                     RKPGSDAIAQAIKCATPGDVILMHDGGGDRSETVEALKEALPYLKKQGFRFITIDELMQ
                     YPKKDI"
     CDS             10001..11908
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_87"
                     /sec_met_domain="ILVD_EDD (E-value: 7.1e-218, bitscore:
                     716.8, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGPENSLEQPGRTHAAHAGHHATACRAARATLVRRSRQYASAGA
                     TVTGIERSPRLAARILERPAAAGVRTAHIRGKRVEPMQLRSDAIKKGLARAPHRSLLKA
                     DGLTDEELERPLVAVISAQNEVIPGHMHLQTIADAVKAGVRMAGGTPLQINTIGVCDGI
                     AMNHEGMHYSLTSREVIADSVECAVQGHQFDAMVLIPSCDKIVPGMLIAACRLNIPTML
                     VSGGPMLAGRDKQGNETDLNTLFDAVGQVTAGTMTEEECAWFENTACPTCGSCSGMFTA
                     NSICCLSEALGLALPGNGTIPAVYSERIRLAKHTGMKVMELLEKGTCALDIINEKSIHN
                     GMALDMAFGGSTNTMLHLTAIAHAAGCPVTMDDWDRISAETPNLTRIAPAGPLHIEDLN
                     AVGGISAIMGELGRCGLLNTDALTCHGTVEEWLAECPPVDGEVVRSKENAFSQTGGLKV
                     VRGNLAPDCGVVKKSAVDPDMWQHSGPARVFESEEEACKAIFGGKINPGDVVVIRYEGP
                     AGGPGMREMLTPTSAICGMGLASSVALITDGRFSGASKGPCIGHVSPEAAAGGPIALVH
                     EGDIIDIDIEAGRLELKVSDEELAARRAAWQPPAPKYTTGVLSRYAKLVTSADKGAYLS
                     "
     CDS             11905..13761
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_88"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-50, bitscore:
                     163.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVDPIAEYKARAISGAPFGPGSHTEKEGQTMTGAQAVIASLEA
                     EGVDVMFGYPGGQAIKIYDALYDSKKIRHVLARHEQGATHMADGYARATGKCGVVLVTS
                     GPGATNTVTGIATAYMDSIPMVIITGQVTRGVIGTDAFQESDIVGITMPVVKHSFLLQS
                     TDDLTKTFREAFYIATTGRPGPVLIDIPSDLASTQMVFHYPDSVNLPSYRPTYKGNAKQ
                     IKQAINLLAQSKRPLLYVGGGVVASHACAELSRFAEMTQIPVVTTLMAKGAFPTSNPLD
                     LGPVGMHGSKYANMAMTECDLLIAVGARFSDRVTGKLSEFAPHAKVIHIDIDPAEIGKI
                     RDPQVPIVGDAQGILAGMIEQAEKAGIGSVGAEWFAQCCEWRKRWPFYHDEFIDYPSQI
                     VPEVALDALSSKLDSATSIVTTEVGQHQMWAHQHIARDTTRSFLSSGGLGTMGFGFPAA
                     VGAKIGCPDKQVVCVAGDGSFQMNEQEMATAIINNAAVKVMILDNRALGMVHQWQKLFY
                     NERYSSTILDPVPDFVKLADAYGWQGERIEDPDQVEDAIQRMLDAEGPYLLDVAISADQ
                     NVYPMVAPGAALDDIIGAIDLTVGGVRVSEKGAGNAAAKEGE"
     CDS             13764..14246
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_89"
                     /sec_met_domain="ALS_ss_C (E-value: 7.3e-31, bitscore:
                     98.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHILSVLVENKPGVLSRVTGLISRRGFNIESLTVAPTEDETMSR
                     MTIVMDADDLGYEQITKQLHKLVSTYKISDMTGEDTIERELALFKVAAGPERRHEVIEI
                     ANVFRAKVVDVGKNSLTIEATGDADKLGAMEDLFRAYGIKQLTRTGKVAMSRGARD"
     CDS             14597..15592
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_90"
                     /sec_met_domain="IlvN (E-value: 8.1e-78, bitscore: 252.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.2e-63, bitscore: 206.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVTIYYENDVDPKVIQGKKIAVIGYGSQGHAHALNLMDSGCDVR
                     VGLREGSSSWAKAEEAGLKVTDMDTAAEEADLIMILVPDETQPKVYEEHIAPHLKAGDT
                     LAFAHGFNIHYGYIKAPEDVNVIMCAPKGPGHIVRRQFVEGSGVPDLACVQQDATGNAW
                     DIALSYCWGVGGARSGIIKATFKEETEEDLFGEQAVLCGGLVELVKAGFETLVDAGYPP
                     ELAYFECYHEMKMIVDLMYESGIHFMNYSISNTAEYGEYYAGPKVINEQSREAMKLILE
                     RIQNGEFAKEFVEDCNNGHKWLLEQREAINEHEIEKTGEKIRSMFTWIKK"
     CDS             complement(15825..15923)
                     /locus_tag="ctg8_91"
                     /transl_table=11
                     /translation="EWMRWFREGRISQKLGWLTPDERRAALGYPVL"
ORIGIN
        1 tcgggggtct ctggggctca ggcttagccg gcgccgccga agctcccggg gcttccggag
       61 cctccgaagc cgcaggcgcg gcaggctccc ccgaagctgc ggaatccgaa ggcgcgccag
      121 atgcgctttc ctcggttgcg ccatgcgctt gatcggcgct gacctccacc gtaatgccgg
      181 aggcgtcttt gccaataaga ccggccttct ccttggccag atactcatcc cacgtattgt
      241 cgagcagcgc gtcgcatgcg gcgccgtcca ccgtctcacg ctcgagcagc acttcggcca
      301 tcaggtgcat ttggtcggcg tgctcagaca ggatcttata cgccgtatcg tgcgcctcct
      361 tcatcaggcg agccacttcc tcgtcgatgc gctgcgccgt ctcgggcgag tagtcctgcg
      421 tgttgccgta atcgcggccc aggaacacct cgtggttggg ctggccgaac gtctgctggc
      481 ccaatgcgtc ggacattccg tagctcgtca ccatcttgcg cgcctgtttg gtggcacgct
      541 cgaggtcgtt gctcgcgccg gtggtgatgt cgccgcagaa gatttcctcg gcgacgcggc
      601 cgcccatgaa cacggccaaa tcgtccacca tctcgttgcg gctgaccaag aacttgtcct
      661 cgtcggggat ggacatggtg tagcccagcg ccatgccgcg cggcacgatg gtgatcttgt
      721 gcaccgggtc ggcattggga agcagatgcc ccaccaaggc atggccgctc tcgtggtacg
      781 cgatgatctt gcgagtcttc tcgttcatca cgcggttctt gcgctcgggg cctgccatca
      841 ggcgctccat ggattcgttg acttcggcca tgccgatgat cttcttgttg cggcgcgcgg
      901 tgagcagagc cgcctcgttc atgaggttca tgaggtcggc gccggtcatg ccgctcgtga
      961 gcttggcgat gcgctgcaga tccacatcgg ggcccagggg cttgttctta gcgtgcacct
     1021 caaggatctt ctcgcggccg cgcacatcgg gtgcgtccac cacaatctgg cgatcgaaac
     1081 ggccgggacg cagcagggcc gggtcaagca catccacgcg gttggtggcg gcaatcagca
     1141 ccacggcatc gtttttctcg aagccgtcca tctcaaccag cagctgattg agggtctgct
     1201 cgcgctcgtc gtggccgccg cccaggcctg cgccgcgctg gcggcccact gcgtcgatct
     1261 cgtcgatgaa gatgatggcg ggagcagcct ctttggcctg cttgaacagg ctgcgcacgc
     1321 ggcttgcacc cacgcccacg aacatttcca cgaactcaga gccggagatg ctgaagaacg
     1381 gcacctgcgc ctcgcccgcc acggcgcgcg cgagcagcgt cttgccggtg cccggaggac
     1441 ccaccaaaag gcagccgcgc ggaatcttgg cgcctaatgc ctgatacttc tgaggatcgg
     1501 tgaggaagtc cttgatctcc tggagctcct caaccgcctc gtcctcaccg gccacatcgg
     1561 agaatttcac atccggatgg tcaacggtgt actccttggc cttcgccttg ccaaacgaca
     1621 tctgcgaatt gttcgccttg ttcatctgca cgaagaagaa gatcatcacg ccgatgagca
     1681 gcagcatggg caagaagctc agcagcgtgt cgagcaggcc gttgggcagc tgcaccgtat
     1741 actggatgtc aggatactgc gaaagcagct gcatgagcga gtcctggccc acataggtgg
     1801 aggtatagtt gcgcagctcg cccaaggatt gggtctcaag cgtctgggtt tccacgcccg
     1861 catcggcgcc aagagccgac tccatctgag cattcagcga ttcaaatgcc ttgttgtagg
     1921 catccgccgc cgtagagccc gccgtggcag cgggatagta ctggccggac acggtatagc
     1981 ttccggcgtc gtaaaccacg ttttcaacgc ggccctgctc caccgcctgc acgaactcag
     2041 acgtaaccag cgtatcggtc tgctgggtgc cccccatcag attcatcatc tggctgccga
     2101 tgaagaacgc gatgaggaag aacagcacgg cggacacgat gctcatgcgc tgcggagggc
     2161 gagggctcaa ttgtttggaa tccttggaac catccgcatc gccgcccatg gtaaacagcg
     2221 agccgaagcc ctcgggctca ttgcccttgc cgtcagggcg ctgccgccca cgggcaggct
     2281 ggttcggagc ttgcccgtca tttccaggct gctgcggttg gggcgtttgc ggcgcaggcg
     2341 gctgcggagg ctggggcctg cggtcgcggt cgttgggatt ggtaggggta tcgctcatta
     2401 tcttccttgg tacacttcgg gcttcagtac tccgatatag ggcaggttgc ggtagcgctc
     2461 cgcaaaatcg agcccgtagc cgacgatgaa ctcatcgggg cattcgaagc cgatatactt
     2521 gcattcgatt tccgcctgct gcgggttgcg cttgcgcagc agcgtggcca cctggatgga
     2581 ggccggattg cgcgattcga gcacgcgcag caggtacttc agcgtcaggc cggaatcgag
     2641 gatgtcctcg gcgatcagca cgtggcggcc ttccacgttg gacgtaaggt ccttgatgat
     2701 gcgaaccaca ccggagcttt tcgagccggt gccgtacgac gagaccgcca tgtaatccat
     2761 ctccagcgga agatcgatcg cgcgcaccag atcggacatg tagatggcgg cgcctcgaag
     2821 aacgctcacc accagcagcg ccggatcgcc atgaggcgta ggctcatagg cggcgtcgcg
     2881 atagtcctcg gtaatctgct cgccgagctc gcgcacgcgc tgaacgatgg cgtcctcggt
     2941 gaacagaact tcgcgaacgt ctgcgtcgcc gtgatactgc gaatcatgtg cctgggtcgt
     3001 ggacatggca ccctttctca tcgaatggac aactgatggt gcagtgtatc accgaaggta
     3061 aggacgcgcc tcaacgatac ggcaacgacg taccgaaaaa cacgatttcg caacgtcggc
     3121 gtggacaaat gcggcgcacg cggggcatca atccccatgc cgtacctcgt tcgcaacgct
     3181 cctccccgcc gccttcatca cgggcagcgg cttggcgggt gcccgcgttt cacgcccgat
     3241 gttgattcgc gcccgacacg caagcgccca accgcatctc ggctcgcact atgccgattc
     3301 ctctccgaat aaggaggaag gcgcgttacc gtaacgcgcc ttcgcattgt tttggcttgc
     3361 acggattgct cgcacgcgat gcgcgcaatc ccactcggag catcgagcgc atgcggctga
     3421 tccgctagga cgaggagggc ctagaaatag tacacagccg agctcgcccc cgttgcagcg
     3481 gcaccgatgg ccgcgcaggc agtgaatccg aacagcatca gcagcaagat ccagcctacg
     3541 atggacacca aaaagccaat gagggaaaac ttgaccgcct cgcttttggc ctgcggaaag
     3601 ttatgcgcat tcgtgagcca cgccacgagt atggcgagag ggcccaggaa gaatcccagc
     3661 gcagcccagc cgaatttcat gccgcccgtc agataaagca ggggcatgcc cggcatgttc
     3721 tgcggcatcg gctgaggagg cacggcgggc gccgggccga acggctgctg gggcggaact
     3781 tgaccggcgg gcggcacctg cccggtcgga ggcacgttgc cggcgggcgg aacctgcccc
     3841 gctgcgggcg cgaaccccgc tagtggcacc gggttcgttg tcacgggctg ctgttgaacc
     3901 gacgcggcgg cgggctgggc ctgtgcagcg gcgggctgtt cttgaacggg agccgacgcc
     3961 gtttgaggcg tgggttgctc gggattggtg ttagtggtgg cgtcagccat gattcctcga
     4021 ttcctcggaa tggtcgaata ttgcccgatt atacccagcg cgcaccgtaa attgcactac
     4081 gccacaaagc gcaattgttt cgtcgcaaag ccgtaatgct tctgtaagaa accatgcacg
     4141 ttttcttaac cgcccgccac aacaaagcgg ggcaaccgga cgctatccga ttgccccgct
     4201 tattcagctc catgcatcgc ccgccaaaag agcagagcgc ctttcgcgtt agccacgatc
     4261 gaaaggcagg gcgaagcatt tggcagtttc gcaacgacga ttacgccgcg ttggcacgag
     4321 cggcgcaatc gcctgcttag cccgtatagt cggcaccaag aatgaccagg aaattcccgt
     4381 caaacgtgta gctgccgtcg ttgagcatgg tggtgcccac gcccagagcc tcgccgatgg
     4441 aacgcgcctc cgactccatg ctgctatcgt tgtacacaat gagcgtgctt gcgtaatcgt
     4501 agttatcggc gtcgcccgtc tcggtcacat cgtacccgct gttggtgagc acgctcgaag
     4561 cagttgccgc cacgccgctc acgccgtttc cgttgcgcac cgctacggcg ttctccgacg
     4621 ccaggctgcc ggtattgccc gaatcagcca gcgcgctctg cgcgatgtac tccttgtcca
     4681 gcgttccatc ggtcacgccg ccgcggttgg cagaatcctc ctcatttacc gtgggagaca
     4741 ggccctgatc gacgcgcgtc atcatggcct tccacgcctc tacgttggtg tactcgatcc
     4801 acaccccgtt ctcatacgcc gacacagtgg gattcatgca cgagtagatg cccgaatcgg
     4861 tatccatgcc ctgcatttgg agcgcgatgc tcacaatctc gtccacgctc atatcggtgg
     4921 tgatgtaatc ggccatagag ttgaccacgc tcgccatagt ggccggatcg ctggcgagca
     4981 gtttcttggc gatggcaccg atcaccagac gctggttggc ggcgcgatag gtgtcgccgt
     5041 cgccctggtc gtcgtaggaa tggcggctgc ggcacagaat gagagcctgg tcgccgttga
     5101 gcgtctgctc gcccgcctcg aggctgccgc cggcctgcgg gtcgtctatg tcgcgcggca
     5161 cgttcacttc gatgccgccc agcgagtcca ccgcctcctt gaagccgtcg aaattgatct
     5221 cggcatagtg agagatgggc acgcccgcgt actccgacac cacctcgacc gcataggcgg
     5281 gaccgccgat ggcgtgagcc gcgttgatct tctgatagcc gttttcgccc atatccacat
     5341 acgtgtcgcg catgatggaa acgagcgtga cctgcttttg ttgggggtcg atgcgcgcaa
     5401 ggatgatgga gtcgctgcgg aaggtgtcgc cggcgtattg ctcgctgttc tcgcgctccg
     5461 atgaaccatc cacgcccatg agcagcacgt agaagggctc gctcgattcg gtgacggtga
     5521 gctggttgag cagattgtcg tccacgccct gttgcagctt gctgttgatg ccgcccaaaa
     5581 acaccgccgc agcggcgccc gcgcccacta cgagcgcaag aatgacagcc actacgccca
     5641 cgaccacctt tttgcggcgc gacttcttgg cgcgctgctg agtgtaggcg tcctgcgtcg
     5701 cgcggcgcga atactgctgg gcagcggtct ggcgaccggc acccctatca aggccgctcg
     5761 catcatcgcc acgacgggga gtcgtcgaat ggcggcgcgg ctcggcagtg ggaaagttgt
     5821 cgaatttcga agatctacgt gccacgggat ctccaatctc aggtcgttga atcgaaatcg
     5881 gccttttatc ctacgcgtgc gagtgaaaat tcgggagttc atccgaacac atttcatccg
     5941 ctctccggcg aatcaccata tccttaaccg gcttttaaac cgaaaaacgg ggccgaaagc
     6001 cttgcgctct cgaccccgcg tccgccataa aggcctagta atagccctct tcgtaatacg
     6061 aagcgtcatc gtaataggcg tcgtcgtaat acgtctcgtc ggtggcgccc gatgattcgc
     6121 cgcttgattc ggtggcgtcg gcggattccg aaagcgaatc ctccagcgcc gctgcggccg
     6181 aatccgaaag atccgcgttc tcggcgccat attcttgaac gcccgtcacc gtgccgtcca
     6241 ggccgccgcc gtcgttcttg ttacggtcct cgtctttgta gggaggaagg ccctggtcga
     6301 cacgcgacat catatcctgc cattcctcgg tgttgcagat ttcgtaataa atgccgtcaa
     6361 tcagctgcga cacggtgggg ttcatcgcgg aatagatgtc gttttcggtg tccatcccct
     6421 gcatctgcgt ggcaatggac acgatttcct ccacgttgaa atcggtggtg atgtaatcgg
     6481 ccatggaact gatggtgttt gccatggtca ccggatcgct ggcgagaagc ttcttggcga
     6541 tggcgcccat gaccatgcgc tggtttgcca tgcggtagta gtcgccgctg ccgtaatcgt
     6601 cgtaagcgtg acggctgcgg cacagaatga gggcctggtc gccgttgagc gtctgctcgc
     6661 ccgcctccac acggccgccg gcctgcgggt cgtcgatggt catgggcacg tccacctcga
     6721 tgccgcccag cgcgtccacc gcctccttga agccgtcgaa gtcgatggcg acatagtgcg
     6781 aaatatcgac gcccgcgaat ttctcgatgg tcttcacggt gagcgccgcc ccgccgtatg
     6841 ccgcggcggc gttgatcttg ttgggaccgt agccttcgat atcgacatag gtgtcgcgct
     6901 cgatggacac gagcgtcacg gttttctgct gaggatcgac gcgcgtaagg atcatggagt
     6961 cgctgcggaa ggtgtcgcca gcaaactccg cgcggttggc gcgctcctcg gacttgtcga
     7021 tgcccataac aagcatgtag aacggctcgt cgggctgcac ctcttcttcg ggggtcagca
     7081 ccgcctccag ctcttcgtcc acgccttcgt gcatctggtt ggagatgctg ttcagataga
     7141 ggtagccgcc aaacgccacg ccgccaaaga gcagagccac gatcataact acgagcagag
     7201 caataagccc cttgctgcgc tttttctttg acgtgtagtt ggcgcgcgaa tacgccgccg
     7261 cgccggtagc gccggtggcg ggaggaagcg cattggtttt cggagtgcgg cccgatgcgt
     7321 gacgcgaccc gccgtaggac acggggcgca cggtagaggg catctggccg tagtgtttgt
     7381 tgtctcgttt attcatggcg catattatcg cgcgtttgcc ctgcgttcat aaagaaaccg
     7441 taggaaatcc taccgcccca gcgcgcggct ttgtgcatcc gtgaacgggt tgagtttccg
     7501 gtgacagtat tggagaaacg atgcgttcgt aaacgattgg atgaacgact tgcaaaaagg
     7561 ggagaaacgt ggttaaggtt gtctccgcgc ttaaaaaaga acgcacgcgc gatatgatgt
     7621 cgcgtaaaga cacactccgc cttcctcgaa ccacaatcgc accacgaagg gttttcagat
     7681 atgagcactt ccagatcagg caatcatccc tcaggccgcc cctccgttgc gggcaagcgc
     7741 accgttcacg gcagcggatc cgcatcgaaa tattcgcgtg attcctacgt cggacgcagg
     7801 tcatcctctc cgagcgcacg ccgcaccatc ggcggctctt ccgttgcgca cgacgccgat
     7861 gacgctgcgc gcatggcagg cggcaccgga cgccaggggg caatcgcaga cgcttccgac
     7921 accgggcgtt acagcgtggc gcccgatccc tctagcaccg ggcgctacgc cgcagaccgc
     7981 tatgcgggac gcagctcctc gggcagaccg tcggtgcgtt cgggaagaac gaacacgcgc
     8041 cgatcgggca cctcatacga accgcttttc gacgagtccg ccgacggcat cggccgctcc
     8101 atccgccgcc gccgcgcgct gacgcgcggc gttatcgccc tggccgccat cgccgtcgca
     8161 ataggaggcg tggtgttttt catgtcgaat gcgcccatca cggtgagcgt gaacggcaac
     8221 tccatagatc tgtcgggcgc caaaacggtt caggccgcgt tcgaggcggc aggcgagccc
     8281 gcgaaggcag gcaacctggt ggatgtcgaa ggggccacgc tcgaagaggg caagggatac
     8341 cagttctcgt tcgccgtgaa cggccagccc ggcaccgacc ccacctctcc gctcaaagag
     8401 ggcgacgcgg tggtgttttc cgacggcgga gatatcgagg aagagtccga ctcgacagac
     8461 gagcccatac cccacgaaac agtggaccag ggatatggcc ctatccatat ggttgacaac
     8521 cccggagccg atggcgtgaa gaccacgaag accgggaaga tttcgggcaa aactgtcacg
     8581 caaaccactg ccgagccgca agatcgcgtc tatcgccgct actatcccga cacgggcgag
     8641 gacaaagtgg tggcgctcac cttcgacgac ggcccctggg acacttccac cgccgagatc
     8701 ttggacatcc tcaaggcgaa cgacgctaaa gccacatttt tcaccgtggg caaccgcatc
     8761 gatgacagca cggccgacct gataaagcgc gaggtagcag aaggtcatca agtctgcacg
     8821 cacacgtggg atcatgccgc gggcagcggg cagggggtca acctatcgtt catgtccaaa
     8881 gacgaacagc gcgaggaaat aaccaagggc atgaaggcca tctccgacgt aacgggccaa
     8941 gaggcgagca aggtgattcg ctcccccggc ggcaacttcc ccaccgaggt gtggatgaac
     9001 gtcgaagacc tgattaccgc cgaaatcgga tgggatatcg acaccgaaga ctggcgcaag
     9061 cccggatccg atgcgatagc ccaggccatc aaatgcgcca cgcccggcga tgtgattttg
     9121 atgcatgacg gaggcggcga tcgctcagaa acggtcgaag cgctgaaaga agcgctgccc
     9181 tacctaaaga agcaggggtt tcgcttcatc accatcgacg agctgatgca gtaccccaag
     9241 aaagacattt aagcgcgaga tccgcaaagg agcctacgcg ggaagcgaac ggggggttat
     9301 ggcgggagcg atgtcgcaaa agcgtgtcca attaacccta tgagggacca tgtgcgatgc
     9361 atatcattac ggaaccatgc ggtctcatat agaaccacca tatagaagag aaaggcgccc
     9421 gcttgaggcg ccttttttat tgccgcccgc tcgaaggggg atggagcaag cagcctttga
     9481 gacagcgagg attcgagcga agggggtagt gtttcgactc gttatttatc cttgcacgag
     9541 aataataaca cctctcatgc ggctgcacaa catctatatc ctaaattgag gataattatt
     9601 gtgacgcccg caaagcccga ccgctcggcg gcggctgcgg aagagtccga cctcgacagc
     9661 agccgcgaaa agctgaccgc ccggcagcag tcgcgaaaaa cccaccgctc gatggcggtc
     9721 gaggaaagcc gattgctggg cagtagccgc ggaagaaacc caccactcga tggcggctat
     9781 aggaaacgcc cttcaagccc attgacaaaa ctacagcccc atcccaacga gggaaatatt
     9841 tcgcacgcgt taaatctggg cactttcgca gaataaagtg cgatagcgtc ttgaagcggc
     9901 gccccacggt cctataatca gttcacttga gcaaatgcga cgacagggcg agtagggacg
     9961 aatccatccc acagcaagca ggcggtcttg agaacctgcg atggacggcc ccgaaaactc
    10021 cctcgagcag ccaggcagaa cgcacgccgc gcatgcgggg caccacgcca cagcatgccg
    10081 cgccgcacgg gcaaccctcg tgcggcgctc gcgtcagtac gcctcggccg gcgccaccgt
    10141 taccggcatc gagcgaagcc ctcgcctcgc cgcccgcatc ctcgagcgcc ccgcagccgc
    10201 gggcgtcaga accgcacaca ttcgaggaaa gcgagttgaa ccgatgcagc ttcgaagcga
    10261 tgccatcaaa aaggggcttg cacgcgcccc gcaccgcagc cttctgaagg ccgacggcct
    10321 gaccgacgaa gagcttgagc gccccctggt cgcagtcatc tctgcgcaga acgaggtcat
    10381 tcccgggcac atgcacctgc agaccatcgc cgacgccgta aaggcaggcg tgcgcatggc
    10441 cggcggcacc ccgcttcaaa tcaacaccat cggcgtatgc gacggcattg ccatgaacca
    10501 cgaaggcatg cactactccc tgaccagccg cgaggtcatc gccgatagcg tcgaatgcgc
    10561 cgtacagggt caccagttcg atgccatggt gctcatcccc agctgcgaca aaatcgtgcc
    10621 cggcatgctc atcgccgcgt gtcgcctgaa tatccccacc atgcttgtga gcggcggccc
    10681 catgcttgcc ggccgcgaca agcagggcaa cgagaccgac ctgaacaccc tcttcgatgc
    10741 cgtgggccag gtgaccgccg gcaccatgac cgaggaggag tgcgcctggt tcgaaaacac
    10801 cgcctgcccc acctgcggca gctgctcggg catgttcacc gccaactcta tttgctgcct
    10861 gtccgaggcg cttggcctgg ccctgcccgg caacggcacc atccccgccg tgtactccga
    10921 gcgcattcgc ctggcgaagc acaccggcat gaaggtgatg gagcttttgg agaagggcac
    10981 ctgcgcgctc gacatcatca atgagaagtc catccacaac ggcatggcgc tcgacatggc
    11041 attcggcggc tccaccaaca cgatgctgca cctgaccgcc atcgcgcatg cggccggctg
    11101 ccccgtgacc atggacgact gggatcgcat ctcggccgaa acccccaacc tcacgcgcat
    11161 cgcgcccgcc ggcccgctcc acatcgaaga cctcaacgcc gtggggggca tctccgccat
    11221 catgggcgag ctcggccgct gcggcctgct gaacaccgac gcgctcacct gccacggcac
    11281 cgtggaggag tggcttgccg aatgcccgcc ggtggacggc gaggttgtgc gctccaaaga
    11341 aaacgctttc agccagaccg gcggcctcaa ggtggtgcgc ggcaacctgg cgcccgactg
    11401 cggcgtggtc aagaagagcg ccgttgaccc cgatatgtgg cagcactccg gccccgcccg
    11461 cgtgttcgag agcgaagagg aagcctgcaa ggccatcttc ggcggcaaga ttaaccccgg
    11521 cgacgtggtg gtcatccgct acgaaggccc ggctggcggc cccggcatgc gcgagatgct
    11581 cacgcccacc agcgccatct gcggcatggg cctggcgagc tccgtggcgc tcatcaccga
    11641 cgggcgcttc tccggcgcct ccaagggccc gtgcatcggc cacgtgtccc ccgaagccgc
    11701 agccggcggc cccatcgcac tcgtgcatga gggcgatatt atcgacatcg acatcgaggc
    11761 cggccgcctc gagctgaagg tatccgacga agagcttgca gcgcgccgcg cggcatggca
    11821 gccgcccgcg cccaagtaca ccacgggcgt gctctcgcgc tatgccaagc tcgtgaccag
    11881 cgcagacaag ggggcgtatt tgtcatgaca gccgtcgacc ccattgccga gtacaaggcg
    11941 cgcgccattt ccggtgcgcc cttcgggccc ggcagccaca ccgaaaaaga agggcagacc
    12001 atgaccggcg cccaggccgt catcgcaagc ctcgaagccg agggcgttga tgtgatgttc
    12061 ggctatccgg gcggtcaggc catcaagatc tacgacgccc tgtacgactc caagaaaatc
    12121 cgccatgtgc tggcgcgcca cgaacagggc gccacgcaca tggccgacgg ctacgcccgc
    12181 gccaccggca aatgcggcgt ggtgttggtg acaagcggcc cgggcgccac caacaccgtc
    12241 acgggtatcg ccactgccta tatggattcc atccccatgg tgatcatcac cggccaagtc
    12301 acgcgcggcg tcatcggcac cgacgcgttc caggagtccg atatcgtggg catcaccatg
    12361 ccggtggtca agcacagctt ccttttgcag agcaccgacg acttgaccaa gacgttccgc
    12421 gaagcgttct acatcgccac caccggacgc cccggccccg tgctcatcga catccccagc
    12481 gaccttgcca gcacgcagat ggtgttccac taccccgata gcgtgaacct gcccagctac
    12541 cgccccacct acaagggcaa cgcaaagcag atcaaacagg ccatcaacct gcttgcccag
    12601 tccaagcgcc cgctgctcta cgtgggcggc ggtgtggtcg cgagccacgc atgcgccgaa
    12661 ctttcgcgtt tcgccgaaat gacgcagatc cccgtggtca ccacgctcat ggcgaagggc
    12721 gccttcccca cctccaaccc gcttgactta ggtcccgttg gcatgcacgg ctccaaatac
    12781 gccaacatgg ccatgaccga atgcgacctg ctcatcgccg tgggcgcacg gttctccgac
    12841 cgcgtaacgg gcaagctttc cgagttcgcg ccgcacgcca aggtcatcca catcgacatc
    12901 gaccctgccg agatcggcaa gattcgcgat ccgcaggtgc ccatcgtggg cgacgcgcag
    12961 ggcattctcg ccggcatgat cgagcaggcc gaaaaggcgg gcatcggctc cgtaggcgcg
    13021 gaatggttcg ctcagtgctg cgaatggcgc aagcgctggc cgttctacca tgacgagttc
    13081 atcgattacc ccagccaaat cgtgcctgag gtggcgcttg acgcgctgtc ctccaagctt
    13141 gattccgcca catccatcgt caccaccgag gtgggccagc atcagatgtg ggcgcatcag
    13201 cacatcgccc gcgacacgac gcgatccttc ctttcgagcg gcggcctggg caccatggga
    13261 ttcggcttcc ccgccgccgt aggcgccaag atcggctgcc ccgacaagca ggtggtatgc
    13321 gttgccggcg acggcagttt ccaaatgaac gagcaggaaa tggccaccgc catcatcaac
    13381 aacgccgccg tgaaggtgat gatcctcgac aatcgcgcct taggcatggt tcatcagtgg
    13441 cagaagctct tctataacga gcgctactcc tccaccatcc tcgatcctgt acccgacttc
    13501 gtgaagctgg ccgatgcata cggatggcag ggcgagcgca tagaggaccc cgaccaggtt
    13561 gaggatgcca ttcagcgcat gctcgatgcg gaggggccgt accttctgga cgtagccatt
    13621 tcggccgacc agaacgttta ccccatggtg gcgccgggcg ccgcgcttga tgacatcatc
    13681 ggcgccatcg accttacggt gggcggcgtg cgcgtgtccg agaagggcgc cggaaatgca
    13741 gcggcaaagg agggcgaata atcatgaagc atattctctc cgtgctggtt gaaaacaagc
    13801 ccggcgtgct ctcgcgcgtg accggcttga tttcgcgccg tggcttcaat atcgagtcgc
    13861 tcacggtggc ccccaccgaa gacgaaacca tgtcacgcat gaccatcgtt atggatgccg
    13921 acgacctggg ctacgagcaa atcaccaagc agctccacaa gctggtaagc acctacaaaa
    13981 tcagcgacat gaccggcgaa gacaccattg agcgcgaact ggcgctattc aaggtggccg
    14041 ccggcccgga gcgccgtcac gaggtaatcg agatcgccaa cgtgtttcgc gccaaagtgg
    14101 tggacgtggg caaaaactcg ctcaccatcg aggccacggg tgacgccgat aagctgggcg
    14161 ccatggagga cctcttccgc gcctacggca tcaagcagct cacccgcacg ggcaaggtgg
    14221 cgatgtcacg cggggcgcgg gattaggaga gttccgccgt tcttccgaac ggcggacaac
    14281 tcgacgctgc ggtgcggtgc ggcgagccgc cttgccgctc caagccttcc tcacgtagcg
    14341 ctgctacgct tcgtcaggct ttcacggcaa ttcgccccac cgcaccgccc ctcgctgact
    14401 tttttggcga cctgcaggac tgcgtatcgg atgcccggca tgggtgtgcc acgcgcagtt
    14461 ccgcacgagc cggacgtgcc gttcccggca cgtccgtgcg agcaggactg tttgagcatg
    14521 gcgcacccat gccgggcatc tgggctcgca atatgttcat ccagtaatca gcagtcaaag
    14581 gaaaggaaga ttgagaatgg ctgttactat ttactatgag aacgacgtcg atcccaaggt
    14641 tattcagggc aaaaagatcg ccgtcatcgg ctacggctcg cagggccatg cgcatgcgct
    14701 gaacctgatg gattccggct gtgacgtgcg cgtcggcctg cgtgagggct cttccagctg
    14761 ggccaaggca gaggaggcag gcctgaaggt caccgacatg gacaccgccg ccgaagaggc
    14821 cgatctcatc atgattctcg ttcccgacga gacccagccc aaggtgtatg aggagcacat
    14881 cgctccgcac ctcaaggccg gcgataccct ggcattcgcc catggcttca acatccacta
    14941 cggctacatc aaggcgcccg aggatgtgaa cgttatcatg tgcgccccta agggccccgg
    15001 ccacatcgtg cgtcgccagt ttgtcgaggg ctccggcgtg cctgacctgg cttgcgtgca
    15061 gcaggacgct accggcaacg catgggatat cgcgctttcc tactgctggg gcgtgggcgg
    15121 tgcccgctcc ggcatcatca aggccacttt caaagaggag accgaggaag acctgttcgg
    15181 cgagcaggca gtgctctgcg gcggcctcgt cgagctggtc aaggccggtt ttgagaccct
    15241 ggttgacgcc ggttatccgc ccgagctggc ctatttcgag tgctaccatg aaatgaagat
    15301 gatcgttgac ctcatgtacg agagcggcat ccacttcatg aactactcca tctccaacac
    15361 tgccgagtat ggcgagtatt acgccggccc caaggttatc aacgagcaga gccgcgaggc
    15421 catgaagctc atcctggagc gtatccagaa cggcgagttc gccaaggagt tcgtcgagga
    15481 ttgcaacaac ggccataagt ggctgctcga gcagcgcgag gccatcaacg agcacgagat
    15541 cgagaagacg ggcgaaaaga ttcgctccat gttcacctgg atcaagaagt agttcgccgc
    15601 gccgctcttc cgaacgtcgc acttctcaaa gaagcgccgc ggcactgccc cgaggacgtt
    15661 agccgcatac gcatgagatg agtacagggc cccgagcagc tgctcggggc ccaggagtat
    15721 gcaggagctc tctggtattg ctcaaccacc caaatctggc agaaaaatcg agtatgtaat
    15781 ccgaatagcc gtcgcttggg accgcggacg ttttcttgta catcctacag caccggatag
    15841 cccagcgccg cgcggcgctc gtccggggtg agccacccga gcttctggga tatgcgcccc
    15901 tcgcggaacc agcgcatcca ctc
//
