LOCUS       NC_011830.1            22614 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_011830.1 Desulfitobacterium hafniense DCB-2, complete sequence.
ACCESSION   NC_011830
VERSION     NC_011830.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:20:52
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1179788
            Orig. end    :: 1202402
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..276
                     /locus_tag="ctg1_1081"
                     /transl_table=11
                     /translation="MDYKVPHQCPICKHEMHVTKLFCTHCSTTLEGEFHTCKFCKLPDD
                     QLLFVETFLKCRGNIKEVEKELGISYPTVRSRLDSVIQSLSNERKE"
     protocluster    1..22614
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1189581:1192954]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9794..13166
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..22614
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22614
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Others_HGD_unassigned"
                     /region_number="10"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             510..989
                     /locus_tag="ctg1_1082"
                     /transl_table=11
                     /translation="MNIPTSLKHKPVIVSENYENVDGRYAYQSDAKGLSLGLAQWNDRG
                     KVDISAKVWRYTGEKWSRQSEELPLHRVLDLAILVCRTKLHFREAYRYDNFYDPEKPVI
                     DRIGLQGDAMTVAVCTDNEKINEDIKLFNQALCNDDELLGERLRTLSAILKEMGY"
     CDS             993..1343
                     /locus_tag="ctg1_1083"
                     /transl_table=11
                     /translation="MDRKKELKEQYKQMRPDMGIVGVRSGKEAWCYIEGSQNLRAALNG
                     IRFKLEAGFFPCRELMKKWQEQGGENFTFEVLEQLEYDKDETKTDYTDDLVLLLMEWEE
                     KLLDQGFTVAKR"
     CDS             1462..2742
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1084"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 7.4e-90, bitscore:
                     299.7, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKRTIAIFVIIIAALVLGFLFLSQRLNPQEGNLSIPGQHDQQGN
                     NNPAEPSEKPPEIDPLQERIQAMTLEEKVGQLVMVGVDGYEINANAQQLIENYHVGGFV
                     LLKKNVRDSGQMLNLINTLKETNGVNRIPLFLALDEEGGRISRMPAEFKKMPSSQQVGA
                     QNSGALGKKMGEILGREVKGFGMNVNFAPVLDIFSNPKNKVIGDRAFGSNPELVSKVGI
                     QTMRGIQEQGIISVVKHFPGHGDTSVDSHVGLPRVDYDLERLRNFELRPFAEAIANDVD
                     AIMLAHILLPKLDPDYPASFSEVLIRDILRKEMDYNGVVITDDMTMGAIVENYNIGEAA
                     VKSILAGSDIVLVCHDFAKEEAVLKEILHAAETGKIPVDRIDESVYRVLKLKEKYALAD
                     RQKESVDVQGINAEIEQFYKDYPALKG"
     CDS             complement(2863..4455)
                     /locus_tag="ctg1_1085"
                     /transl_table=11
                     /translation="MNTDHPKGHPTPEELLDHYIDILNENGFPEDYDTTEDEQGLYSLA
                     KKVKTLASEPSQEFMASLWQKIEPMAATPSTINAPATANIPAATKDTLRKEGNSLKMPK
                     KFFPWAGFAASILVFLLLFSPWSGSKQTIVMAMEESVKQLQNYHGVLEKVSTNEAGERQ
                     VLIRTEIWSDGENYATKTQDGLLTVNNGETRWSTNPAAKEITLLPVYLDPHDFDLQKEA
                     AKALRYPHQIIGDDTIAGRAATRIEIQPPGGLPYSLWIDQNTHLPIQLQTAMQKSLQTT
                     YTYVSLETNTFLATDIFAYHPPQDYKVIDNNPDKVMASLAEALTASGITPVQLAETPQR
                     MFASANRLVFDFGDTIVMQTKATTPFVPDLLATLGKAGDGPLEILPKSLRWQQADLEIL
                     VQGERAEELAKQLSTNLDFTPQVGPLPQEGVIPVEIDREVVKNSQQQVDAGSSPWQLDP
                     SQVAFTFVALKISPEGITGEPPLDYNALQLTDNDGQKAVIQVSEGPVKTVYLERLIRQD
                     ETGIWTVTGYVPR"
     CDS             complement(4455..4964)
                     /locus_tag="ctg1_1086"
                     /transl_table=11
                     /translation="VESKIGPPASTMETWYQETVTKLYRFIYSQLQNKEETEDITQETY
                     LRCLKQAPDALPPYPYLKQIARNLMTDRYRHKLVAQSHLEHLPEPEHPSPEEEWLTRAT
                     LQELMNQLPSDYRQILEYRIIQGYSRKETATLMGRSESSIRGLQYRALQTLRSYIHLYQ
                     QKGGDL"
     CDS             5107..5628
                     /locus_tag="ctg1_1087"
                     /transl_table=11
                     /translation="MFDQKKLTREIESYLIANQESIYRLAYSYVKHPEDALDVVQESII
                     KAISSVSTLRDSQGMKSWVYRIVVNTALDFLRKQKRLVVVDSETISTYIDEPAAGYEEG
                     SDLDLASALEQLSPAERGRIILRYYEDLKIEEVALVLKENVNTTKSRLYATLKKLRVQM
                     EEPMEEIKHG"
     CDS             5621..6526
                     /locus_tag="ctg1_1088"
                     /transl_table=11
                     /translation="MDKQLSQLKDEYHNTSIPKELEQVVQKAIEDGKKKQQRSRLMMGR
                     KIVATAAAAVVLLIGGINVSPTMASVIADVPGMKTIVQVLTFRDYQYDDGWHQANIEVP
                     AISGLEESGLGQALNQKYLEENKKLYEDFMADVEEMKALGDGHMGVDSGYEIKTDNERL
                     LAIGRYVVNTVGSSSTVFKYDTIDKVDQVLITLPSLFKDDSYVQVISDYIVNEMKAKMK
                     ADSNLIYWVVTDENKDEVNYFEPFTQIKPEQSFYINSDYKLVISFDKYEVGPGVMGMQE
                     FVIPTEVIADRLVSDEYVRP"
     CDS             6714..6863
                     /locus_tag="ctg1_1089"
                     /transl_table=11
                     /translation="MIVLENVGKEFDTEFSLQNITLKVNRGEKILVSGPNGAGKTTFLK
                     YSPA"
     CDS             6906..7199
                     /locus_tag="ctg1_1090"
                     /transl_table=11
                     /translation="MAMIQILVPALLASVGFVAIGLLVSLFSLKSQGRELLANVVSLPL
                     FLPALFIGLSMTVDIAKGMSLPEVWRQVLFLFLYDVFFLAAAYLRFDANYME"
     CDS             complement(7205..8002)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1091"
                     /sec_met_domain="CbiA (E-value: 2.4e-13, bitscore: 48.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRANRHKRVIAVCGKGGVGKTAFTAMLTRSLLESQKAGDLLVID
                     ADPAMGLPNTLGIQVEKTIGHVRDLIINTARAGIGEDRVDLSSRLDYLVLETLYESDDY
                     AFLAMGRTDSQGCFCSVNDLLKKSIRILSERFDTIVIDGEAGLEQMNRQVMNMVDLLII
                     LSDTSTRGLQTVEHITKMVTEDHVIDCTQLGVVFNRVINNELLLTQAAERIGIEVFGMV
                     PQDQSIVHYDLIGQPLTELPADSLALSAIRDFVANHIVQLDCR"
     CDS             complement(8072..8887)
                     /locus_tag="ctg1_1092"
                     /transl_table=11
                     /translation="MSIITSLMEVLPLTRHIIHEDIALAITDRTKFIAYYPAETFAMNI
                     KVGDEIQPGDPVLEVINSGKEFYSIVPKEFFGITIKGGGFPIRDEMGQIIGAVTVARNF
                     EHQAQIDEVAQNIFASLQQTSASVEEIAVGSQKLAHLIENVTKLSEENYHKIKETDIIV
                     TSIKNISSQSNLLALNAAIEAARAGGSGRGFSVVADEMRKLAQNSGEASQKVSNTLSKI
                     KTAEDEIAKQINEISMSGQNQAAATQEITSSLQEIVSSSELLVHLAKVE"
     CDS             complement(8997..9752)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CdhC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1093"
                     /sec_met_domain="CdhC (E-value: 1.1e-17, bitscore: 62.5,
                     seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVFSQYFGKLNQYKNALTQKVDNYWTLSCFQDVAAINPWLVPGQ
                     GRKTGSSIVLKNDVLVELGSPEAGSCSMTLYTNSPHQITDGWITLMGSDITEYTPKKLP
                     FGQVIMVGGEHLTEEDYYYLLQNLNVSEMIEGYMIRSTAESIWCRISKDAAKNGFNFHV
                     LGSVLNWHIKQILPKVKAVEIVFVTTTKEDIEELNQISKEVGEIGRRIKERIWREKGVD
                     IYKCVPGGHCGACEDKTVCDTIRKIGAGR"
     CDS             complement(9794..10588)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1094"
                     /sec_met_domain="BcrAD_BadFG (E-value: 2.7e-64, bitscore:
                     215.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVCGCDLGSATGKAVLLKGDKILSWAVVKSARNPEITAQQVLEE
                     ALDKAGLVKSEIHYVVGTGYGRTGVSFIQDNMSEITCHARGAHWMHPNVRTVVDIGGQD
                     CKVIALDEAGKVLEFGMNDKCAAGTGRFFEAMARVLDCTMSELSTLALNSANPANITKQ
                     CSVFAESEVVTMINNGVKAEDIAAGIHDSIARRIHAMTYKIGIKTDVVITGGCARNEAL
                     TKSLEKQLGVSIHQLTFNPQIAGALGAALLARDRAEKRLIKP"
     CDS             complement(10714..12024)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1095"
                     /sec_met_domain="HGD-D (E-value: 4.6e-35, bitscore: 120.1,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNAAKTGVERTYEYKERINGILGMMEQAPAEQRNPVLEGLLRLI
                     METNERTIDCAENGKPFVSTWYGNAPEILTAMDIHFIVPVFDILLHEYFTDLYDVKEAD
                     KISLPDDICSLIRFGAYAIENKLLPRPTAIISMLEPCDAELMLHQYYQSSEHWGGVPTF
                     GLDPAYGSTDEDFMYFAGELKRLIHFLVEITGQKYDVDKLRKVVAETNTQYELWAEYNE
                     LRRVTPCPHGSFQGSVPLWTLTQFISSGDPRATELIRMMIMDAEAKVKAGIGAVPNEQI
                     RILWADLAPQWGDLLAPWLAEEWGANVVMDYQGYSPYTHIDTTSEDTMLYGLARRALHE
                     VPMIRQGRGTVEVMIEDMTRIIKDYTINCVFWPGHMGHKDVSGSVHFMQELCRSLNVPL
                     LCLTTSLFDERYTPLDKVKQQMSEFFEATGWSKNSST"
     CDS             complement(12027..13166)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1096"
                     /sec_met_domain="HGD-D (E-value: 3.6e-64, bitscore: 215.7,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNTLKTNAMEIFKQAVSTLNNPEVQGWKQQGGKVVGYFYSYIPEE
                     LITAAGLLPYKIRGIGSPGAAMADKYFTHNVCSLVRDTFELVLKGECDFLDGVINFNGC
                     DHIRRISDNWQSLENNPCFHFLVLPKKVGKEQTERYREELVSLKASIEKRFNLVISEDK
                     LKEAIRLHNKKRQLQRRLYELKKRENPPLSGAETLTVMIAGTVMPVARYNRLLAELIDE
                     LSISEGKKPNARLMLIGGELDNPELLKILESQGGMVVSDTMALGAREIACDVSETEDGL
                     TALARYHMEDKPPCPRLYGTFQERFDFIRKTAREYQVDGVISLRFLLCDIWGFEQNDIA
                     EILRTEKLPYLKLETEYALTNAGQLKTRVQAFVETLGEV"
     CDS             complement(13368..13748)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FMN_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1097"
                     /sec_met_domain="FMN_bind (E-value: 1.4e-16, bitscore:
                     59.0, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIAINKIVAMILSVACLISVVGCSAESGADSSKKSGYQDGTYE
                     GISPNGIGGEIAVAVEIAGGKIANVKVTSHGETEGIGTLAVDQLPGKIVEAQSTEVDGI
                     SGASVSSAAIKEAVNDALIKAK"
     CDS             complement(13794..15590)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 142.7; E-value:
                     5.8e-44)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1098"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.6e-42, bitscore:
                     142.7, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHFTRRDFLKGATATAAGVALTGILTGCSSASVGTGNSDPVAPA
                     DSASTGTPTKSTKWYDEAYFKKPASITDIKEKFDVDVVVVGAGNGGCIAAVSAADLGAK
                     VAWVEQNAGPIMWAGEIHALNSKVGKEKYGITFTEAEKNEIVNDICRYASYEVDQRLIK
                     LWADNSGRTMDWFSKKMAAKGVSMHVETDMYKSDMYRTNNRGEHCAYKGEWVEMGPKKM
                     GSEVANPIWVEIATEMGVQKFFEHTALQLLQDSSGKVNGIIVQRKKDNAYIQINAAKGV
                     IISTGGYSGNTEMMDALRYRCKDNVVNNLGGAGHNGDGIKMAMWAGAAIDRNHGGGVAF
                     DRAAVDLDHHTGEPYTSGLDDMWWPGSQPWLAVNTHGERFMNEKAPYDSKIHGASKQPK
                     QIWFQIFDSNYWEDVNAFHTTICSRVVAAPGARNSEVLPGVFPCQTKEEFDKAYMEPAL
                     KSGKLKKADTLEDLAKQLGLPADALAATVKRYNENAAKGFDADFGKDPGSLRPVAQGPF
                     YGIALGNWLLCTFNGVRINTNIQAINENGDPIQGLYVTGNDSGGFFANTYPQYYGGLAH
                     GRTTCFARLAALHAITGSIYES"
     CDS             complement(15780..16676)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     63.4; E-value: 4.6e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1099"
                     /sec_met_domain="LysR_substrate (E-value: 2.1e-26,
                     bitscore: 90.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3.7e-18, bitscore: 63.4,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFFDVQCFLSVAKNLNLSLAAKEMFITQPAMSKKISALEEDFGV
                     KLFNRTRHKVELTSAGKSVQKNFAYILDCYENTKIEAKKIGISEYNHLSIGYHGPTEWA
                     KMNDVVQEFHKRHPHIEIDVVVGDWGPLILDLINGKLDVVFSERSEILDVTILDSIFLF
                     RDFAALAVSKSSPLAQYDQIKPELVKNEKIIMTNNKGAARSLKYIIECLGKAGFDMENA
                     KLADFYETTIAMASAGMGVAPIPRSFKIAGHQSVTYVDIDSDKIPMDFVLAWHINNEKP
                     ALHLFKDFCKQHEWPLT"
     CDS             complement(16784..17185)
                     /locus_tag="ctg1_1100"
                     /transl_table=11
                     /translation="MKMNGNETEECCHDHQHHQTEQRSDNIESHRHNDALVCSGNRNII
                     GDLEVVKKKLRDEMGMFAEWVEKRDGIIGHIKASIEVSGPAFVLSTTGGEVSSREVSST
                     TIHVSIVVIVFQMDKQKTEDQIEALLDKL"
     CDS             complement(17190..17882)
                     /locus_tag="ctg1_1101"
                     /transl_table=11
                     /translation="MRFLAELVYFMNLAGKILGLIYLRRRMHVKIIILGGFLGSGKTSV
                     LLQLAKYLITQERDNKSEIKVAILENEIGTVGIDDKILANAGFTVENLFAGCVCCTLAG
                     ELVSSVKKMQNELNPAWLIIEATGVAFPGSISKAIFEAIGVGAYILTIVDAKRWRRLVS
                     AMEPLVAGQLEESSQVLVNKKDLVNASELAQVKISVQEYSRAAKVICISAKEEIPVQCW
                     QDMISEMG"
     CDS             complement(18012..18644)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) B12-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1102"
                     /sec_met_domain="B12-binding (E-value: 7.6e-20, bitscore:
                     69.3, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKVNEVKISVEMGKTKIVPGLVQAALDEGNTAKELLQAMVDSMS
                     VVGDKFSAGEIYVPEMLLAAKAMAKGVEVLKPHLTGDASASLGTCVIGTVAGDLHDIGK
                     NLVGMMIESAGFDMVDLGVDVPASKWVEAIKENGNVTLVACSGLLTTTMPALKEAVQTI
                     KESGLTGFKIIVGGAPVTQAYANEIGADGYAGDAGSAAIKAKELVNV"
     CDS             complement(18693..19496)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pterin_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1103"
                     /sec_met_domain="Pterin_bind (E-value: 1e-24, bitscore:
                     85.7, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIIGEKINGAIPSVAKAIAEKDVAFIHNLAKIQSNAGADFIDVC
                     ASTDTSIELETLKWLIDLVQEVSDTPICIDSPQAQTCVDAIKFCKRSGLINSVSGEGDK
                     IDVVFPVIADTQWECVALLCDDTGIPKTAEKRLEVFAHIMKRAKEFNIAPSRLHIDPLV
                     EMLCTSEEGINMIMDVIREIKRQYPDIHVTGGFSNISFNLPARKLVNQAFCVLAMNAGM
                     DSGIIDPTNQDLIGMIHATEALLGQDEYCMEYIGAFREGRFGQKK"
     CDS             complement(19863..21410)
                     /locus_tag="ctg1_1104"
                     /transl_table=11
                     /translation="MKLCMGIIEDGISGDIIYKNYLNTDIPFNLERAEMYCESTKVLNA
                     GVLNIAHAENLPEEMIVQEGAALICIGMPAELYTKSPLILLVLDQSKKVAELSNEVNRI
                     FFEYNSLELRLHEAVNKGKSIQYLVEQMAQFLNNELVVMNAEFKLIGQSNSTIHMCEIS
                     GIKQPDSHGRLSTEHVEFFKNDLIYSNVKNMREPFIYEPSIFICRVICMNVFFQDDFVC
                     RVVIAEDRSTFRGYEAGLLHFFTSFIQLVYDLAGYSGDIMPREHMVEIFSALISGESIE
                     SWRLKNSVSQHGWNYDGPFLCASIMPSDRDYYNRTIPYYCQMINRDFKGCCAFEYERKI
                     VCIVNLEYYNGSGECFNSVYLETLRDGYFRVGYSNVFTSIVDIQAHYVQAKISLRIGLD
                     QFPSRWYYKFSDIVLFYMESKLTEELDGQFLCSPKIIGLDSYDRANSSDYLHTLKVYLD
                     NQMNAVKTAKDLFIHRATMVNRLERIKELAGINFKDPDDILYIKISIRLFYKADRRG"
     CDS             21598..22614
                     /locus_tag="ctg1_1105"
                     /transl_table=11
                     /translation="MTITKRENYLMAMNHEKPLWTPVFLYDNAAVGFCAAPGPWFEKGP
                     VGGGYDGFGVRWITPESGSGTPIPAPNEYILTSETVQDWKKLVKFPNVNDFDWEDYAKA
                     ELTPYNRNEVTIDFGSGNGPFERLAALMGFEEALIALLEEPEACDELIGAIVDYKIEVA
                     EKVAKYYKADYFTNYDDIATERGLFMSPSTFRKIIKPHTKRMYDAIRSLGMQPIQHTCG
                     YAQDVIEDFIEMGAQAWTSVQPTNDIVALQKKYGDKISFIGGFNTNGRAAQVDATDEEI
                     VKEVYRTLDTYGPQGSFIFFAYKLANTLDMNKFMAECMRAIGPAIARSMENAGLSQV"
ORIGIN
        1 atggattata aggttcctca tcaatgtccg atctgtaagc atgagatgca cgtgaccaaa
       61 ttgttctgta cccattgttc tactaccctc gaaggagaat ttcacacctg taaattttgc
      121 aagttacctg atgatcagct tctctttgtg gaaacttttc ttaaatgccg gggaaatata
      181 aaagaagttg aaaaggaatt gggaatctca tacccgactg tacgaagccg tctcgacagc
      241 gtaatacagt ccctgagcaa tgagaggaaa gagtgagcac ggccagtctt cagcccatcg
      301 gttagcagac cctgagttat cggggtctgt ttatttttga gtggccaaac tgtcgagtag
      361 tttctgcctt tacgccgata tggtggaaag gggtttgttg acaaaaggta atgtggtggc
      421 tatacttatc tagtaattta gtaaattact agataagtat agcctgatat agatggtcaa
      481 atattatttt ggtgatggag gttttaatca tgaacatacc aacgagttta aagcataaac
      541 cggtgatcgt atctgaaaac tatgaaaacg tggatggccg gtatgcctat cagtctgatg
      601 ccaaaggcct ttctttagga ttagctcagt ggaatgatcg gggtaaagta gatatttccg
      661 ctaaagtatg gagatatacc ggagaaaagt ggtccagaca atcggaagaa ctgccccttc
      721 atcgggttct tgatttagcg attctggttt gccggactaa gcttcatttc agagaagctt
      781 atcgttatga taatttctat gacccggaaa aaccggttat tgacagaatt ggtctgcaag
      841 gtgatgccat gacggtggct gtctgcactg ataatgagaa aattaatgaa gatatcaagt
      901 tgtttaatca agcgctctgt aatgatgatg agctcttagg ggagcgtttg cggactcttt
      961 cagcaattct taaggagatg gggtattaag tcatggatag aaaaaaggaa ctcaaagagc
     1021 aatataagca gatgagacct gatatgggaa tcgtaggggt tcggtctgga aaagaggcct
     1081 ggtgttatat cgagggaagt caaaatctgc gggcggccct taatgggata cggtttaagc
     1141 tggaggcagg gttctttcct tgtcgggagc tgatgaagaa atggcaggag caagggggag
     1201 aaaattttac ctttgaagtt cttgaacagc ttgaatatga taaggatgag accaagaccg
     1261 attacaccga tgatcttgtc ctcttattaa tggagtggga agaaaaatta ttggaccaag
     1321 ggttcacggt agccaaacgg taaactatac atgaataagg aaaataggtt tacaataaga
     1381 ttaagaatag cttggctata tcaggcagca tcgcgctaaa ggccaggctt ttcaaaatag
     1441 tgtgaaaagg taagaggtaa catgggcaaa agaacgatag caatattcgt aatcattatt
     1501 gccgctttgg ttttaggatt tctcttttta tcccaaaggt tgaatcccca ggagggtaac
     1561 ctttccatac caggtcaaca cgatcagcag gggaacaata atccggctga accctcagaa
     1621 aagccccccg agattgaccc cctgcaggaa cggatccaag ctatgacctt ggaagagaag
     1681 gtcgggcagc tggtgatggt gggagtggac gggtatgaaa taaacgctaa tgctcagcag
     1741 ttgattgaaa attatcatgt gggcggcttt gttctcttaa agaaaaatgt cagggatagc
     1801 gggcagatgt taaacctgat caacaccttg aaagagacca atggagtcaa tagaattccc
     1861 ttattcctgg cccttgatga agaggggggc aggatatcca ggatgcctgc tgaattcaag
     1921 aagatgcctt ccagtcagca ggtcggagcc cagaatagtg gtgctttagg gaagaagatg
     1981 ggagaaatcc tgggccggga agtcaaggga tttgggatga atgtgaattt cgctccggtt
     2041 ctcgatattt tcagcaaccc caagaataaa gtgatcggtg atcgtgcttt cggcagcaac
     2101 cccgagcttg tcagcaaagt gggaattcag actatgaggg gaatccagga gcagggcatt
     2161 atctctgtgg ttaaacattt tcccggtcat ggggatactt cggtggattc ccatgtggga
     2221 ttgccccgcg ttgattatga tctggaacga ttaaggaatt ttgagctgag gccatttgca
     2281 gaagccattg ccaatgatgt ggatgccatt atgctggccc acatcctgct gccgaagctt
     2341 gacccggatt atccggcatc cttttcagaa gttcttatcc gcgatatcct gcgcaaagag
     2401 atggactata acggggtcgt gattacggat gatatgacta tgggggctat tgtggagaat
     2461 tataatatcg gtgaggccgc ggtgaaatcc atcctggccg gcagcgatat tgtcctggtc
     2521 tgccatgatt tcgcgaaaga agaggctgtt ctcaaggaga tccttcatgc tgcagagaca
     2581 gggaaaattc ccgtggaccg gatcgatgaa agtgtttatc gtgtcttaaa gctgaaagag
     2641 aagtatgctc tggccgaccg gcagaaagaa tcggtggatg tacaaggtat caatgccgaa
     2701 atcgagcagt tttataagga ttacccggct ttaaaagggt agtgtctaaa gcgataagta
     2761 taagcataca ggtcataaca gttataaagg gagcaagcct tgcctatgtg caagtgcttg
     2821 ctccctttgc gtgtttttgc aggctgcggc ttcagcgctg aatcagcggg ggacatagcc
     2881 tgtgacggtc caaatacctg tctcatcctg acggattaag cgctccagat agacggtttt
     2941 taccggacct tcggatacct gaatgacggc tttttggcca tcattatcag tcagctggag
     3001 ggcattgtag tccagagggg gttcgccggt gattccttcc ggggagatct tcagggcgac
     3061 gaaggtaaag gccacttggc tgggatcaag ctgccaggga ctgcttccgg catctacttg
     3121 ctgttggctg ttttttacca cttccctgtc aatttccaca ggaatcacac cctcttgggg
     3181 aagggggccc acttgcggtg taaagtcaag atttgtggag agctgctttg ccaattcttc
     3241 cgcacgttct ccttgaacaa ggatttccag atcagcttgc tgccagcgca agctcttggg
     3301 taagatttcg agagggccat ctccggcttt gcccagggtg gcgaggagat cggggacgaa
     3361 gggtgtcgtg gcttttgttt gcatgacgat ggtatcgcca aagtcaaaaa ccagacgatt
     3421 tgctgaagca aacatccgct ggggagtttc agcaagctgg acaggagtga tgccgctggc
     3481 agtgagggct tctgccaaag atgccatgac tttatccggg ttattgtcga tcaccttata
     3541 atcttggggg ggatgataag caaagatgtc agtggccagg aaggtgttgg tttcgagact
     3601 gacataggtg taggtggttt gcagagattt ttgcatggcg gtttgcagct gtatggggag
     3661 atgggtgttt tggtcaatcc ataacgaata agggagaccg ccgggaggtt ggatttcaat
     3721 acgggtggca gcccgtccgg cgatagtgtc gtcgccaatg atttggtggg gataacgtaa
     3781 agccttagcg gcttcttttt gaagatcaaa atcgtgggga tccaggtaaa cggggaggag
     3841 ggtgatttct ttggcagcgg ggtttgtgct ccaacgggtt tccccgttgt tcacggtaag
     3901 gagtccatct tgtgtttttg tagcatagtt ttcaccgtca gaccagattt ctgtgcggat
     3961 cagaacttga cgctcaccgg cttcattggt gctgaccttt tccaggacgc catgatagtt
     4021 ttgcagctgc ttcacggact cctccatggc catgacgata gtttgcttgg agccggacca
     4081 gggagagaag aggagcagga agacaaggat gctggcggca aagcctgccc aggggaagaa
     4141 tttttttggc attttgagag aattcccttc ctttcttaaa gtgtctttgg tggcggcggg
     4201 tatattggcg gtggcgggtg cattgatagt agagggcgtt gctgccatgg gttcaatttt
     4261 ttgccagagg cttgccatga attcctggct gggttcggaa gcaagagttt taaccttttt
     4321 ggcgagtgag tagagcccct gttcatcttc tgtggtatca tagtcctcag gaaaaccgtt
     4381 ttcatttaaa atatcgatat aatggtcgag aagctcttcg ggtgtgggat ggcctttagg
     4441 atgatcggta ttcatcacaa gtcccctcct ttctgttgat aaaggtggat gtaggagcgt
     4501 agggtctgta aagctctata ctgcagcccg cgaatggagc tttcactgcg tcccatcagg
     4561 gtggcggttt ccttgcggga atagccctga ataatgcggt actccaaaat ctgacgataa
     4621 tctgagggaa gctgattcat cagttcctga agggtggctc gggtcagcca ctcttcttca
     4681 ggggaaggat gctcaggctc cgggagatgt tcaagatggc tttgggctac taatttgtgg
     4741 cggtagcgat cggtcatcag attgcgggca atctgcttga gatagggata aggcgggaga
     4801 gcgtccggag cttgcttaag acagcgtaag taggtttcct gagtaatgtc ttctgtttct
     4861 tctttatttt gtagttggga gtaaataaag cgatacagct tggttacggt ttcttgatac
     4921 caggtctcca tagtggaggc cggggggcca attttggatt ccacatgttc acctcctcaa
     4981 taacttaaac gagacgggaa aggaaaaggt cacgtttggt taaaactttt tttgttttcc
     5041 cgacgtctgt atagtagaga gagaaaaaac cttctcagat gaagtgcact tcaaaaggag
     5101 tcaggtatgt ttgatcagaa aaagctaaca agggagattg agagctatct catcgcgaat
     5161 caagaatcta tttataggct tgcctacagt tatgttaaac atccggagga cgctctggat
     5221 gtagttcagg agtcgatcat aaaagctatt tcctcagtga gcaccttaag ggactctcaa
     5281 ggcatgaagt cctgggtgta tcgcattgtc gtcaatacag ctctcgattt cctgcgtaag
     5341 caaaaacgct tggttgtagt ggattctgaa acaatcagta catatatcga tgaaccggct
     5401 gccggctatg aggaaggctc cgatctggat ttggcttccg ctctggagca attatctcct
     5461 gctgagcgcg gccgcatcat tcttcggtat tatgaggatc tcaaaattga ggaagtagct
     5521 ttggttttaa aggaaaatgt gaacaccaca aagtcccgtc tctatgctac cctcaaaaaa
     5581 cttcgcgtgc aaatggaaga acctatggag gagatcaaac atggataaac agctttctca
     5641 actaaaagat gagtatcata atacatcaat ccccaaggag ctggaacagg ttgttcaaaa
     5701 agctattgag gatggtaaga aaaagcagca aaggagtcga ttgatgatgg gtcgcaagat
     5761 tgtcgcaaca gccgccgccg cggtcgtgct tttaatagga ggaattaacg taagtcccac
     5821 catggccagt gttatagccg atgtaccggg aatgaaaact atagttcagg tgcttacttt
     5881 tcgggattat cagtatgatg atggatggca ccaagccaat atcgaagtcc ccgccatcag
     5941 cgggttggag gaaagcggac tgggccaggc tttaaaccag aagtatttag aggaaaacaa
     6001 aaaactctat gaagacttta tggctgatgt ggaagaaatg aaagctctgg gcgatggaca
     6061 catgggagtt gacagcggct atgaaatcaa gacagataat gagcggttat tagccattgg
     6121 gcgttatgtg gttaacactg taggatcctc ctctactgta tttaagtatg acaccattga
     6181 caaggtggat caggtcctga ttaccctgcc cagcttattt aaagatgaca gctatgttca
     6241 agtgatcagt gattatatcg tgaatgagat gaaggcgaag atgaaagccg actccaactt
     6301 aatatattgg gttgttacgg atgagaataa ggacgaggta aactattttg agcccttcac
     6361 ccagattaag ccggagcaaa gcttctatat caactccgat tacaaactgg tgatttcttt
     6421 cgataagtat gaagtaggcc ctggagttat gggaatgcag gagttcgtca tccccaccga
     6481 ggtcatagct gatcggctgg tcagtgatga atatgttaga ccctaaccag gataactcaa
     6541 gcttctgtta gaatgatgaa taatcaggtg aatagttaaa ggtaaagaga aacccggcca
     6601 ataaagtttg gctgagtttc tctttctgta taggtggagt gatttatagt agtatgataa
     6661 aaaaatacgc acggggcttg tattgtttaa ggactacaag gtggagggct gttatgatcg
     6721 ttctggagaa tgtaggtaag gaatttgata cagagttctc attgcagaat ataaccctta
     6781 aggttaatcg cggcgaaaag attcttgttt ccggccctaa cggagcaggg aagaccactt
     6841 ttctaaaata ctctcctgcc tgatcgctca cctttccttt catcttattg ttttttaact
     6901 tccccatggc catgatccag atcttagtgc cagcactgtt ggcctcggta ggttttgtgg
     6961 ccattggttt attggtctct ttattttctc ttaaaagtca ggggcgggag ttattggcca
     7021 atgttgtctc actcccctta ttcctgccgg ccctgttcat aggtctcagc atgacggtgg
     7081 atatagccaa gggaatgagc ctgcccgagg tgtggcggca agtccttttt ctgttcctct
     7141 atgatgtttt ctttttagct gccgcctatc tgaggtttga tgccaattat atggagtaga
     7201 atgctcatcg gcagtctagc tgtactatat ggtttgcaac aaaatcacga atcgcgctta
     7261 acgctaaaga atctgcggga agttcagtca atggctgacc gattaaatcg tagtgaacaa
     7321 tggactgatc ttggggaacc atgccaaata cttctatgcc gattcgctca gccgcctggg
     7381 tcaataatag ttcattatta atgactctgt taaacaccac acccagctgg gtgcagtcta
     7441 taacatggtc ttcggtcacc atctttgtaa tgtgttcaac ggtttgtaat cctcgcgttg
     7501 aggtatcgct aagaataatc aatagatcga ccatattcat gacttgacgg ttcatttgct
     7561 ccagtcctgc ttctccatct ataacaatcg tgtcaaatct ttcggagagg atacggatgg
     7621 attttttcaa aagatcattc acggaacaaa aacacccttg gctatccgtt ctgcccatag
     7681 ccaaaaatgc atagtcgtcg gattcatata gggtttccag caccagataa tccagtctgc
     7741 tggagagatc cacccgatcc tccccgatcc cggcacgagc ggtgttaatg atcaagtcac
     7801 ggacatgacc gattgttttt tcaacttgga ttcccagcgt attgggcaag cccatcgccg
     7861 gatccgcgtc aatgacaagc aaatccccag ccttttgact ctccagaaga cttcgcgtta
     7921 acattgctgt aaaagccgtt ttacccacgc cgcccttacc gcatacggcg atcactcttt
     7981 tatgcctatt ggctctgatc atttgttttc cctcatttca ttaactctaa cactcgtgtc
     8041 aaccgagaaa cggtcaactt ctttatctgt tttattccac ctttgccaga tgaaccagca
     8101 gttcggatga agacacgatc tcctgtagag aagaggtaat ttcttgtgtt gctgccgcct
     8161 gattttgccc tgacatactt atctcattga tttgctttgc tatttcatct tcggcagttt
     8221 ttatcttcga taaggtattg gatacttttt gcgaagcttc accgctattc tgagccagct
     8281 ttctcatttc gtcagcaaca acggaaaaac ccctgcctga tcctccagcc cttgctgcct
     8341 caattgctgc atttaaggca agcaaattgg attgactgga aatatttttg attgaggtaa
     8401 caattatatc ggtctcttta attttatgat aattctcttc actaagtttt gtaacgttct
     8461 caattaaatg tgccaatttt tgtgagccaa cggcaatttc ctcaacgctt gcacttgtct
     8521 gctgcaaaga agcgaaaatg ttctgcgcta cttcatcgat ttgagcctga tgctcaaaat
     8581 ttcttgccac cgtcactgcg ccgataattt gccccatttc atcgcggatc gggaagcccc
     8641 cacctttgat cgtaattcca aaaaactctt tggggacaat cgagtaaaac tcttttccgg
     8701 aattaatcac ttccaataca ggatcacctg gttgtatctc atctcccacc ttgatattca
     8761 tagcaaaggt ctctgccgga taatacgcaa taaacttcgt cctgtccgta atggccaagg
     8821 caatatcttc atggataatg tgtctggtta aaggaagtac ctccataaga gaagtaatta
     8881 ttgacatgtt aaatctccat cctccgctaa gtgctaacgg taaggttcag gaagctatga
     8941 gcagcaggcc gccggataat tgcagttcgc ttaatgctgc tcaattcatg gtttccttat
     9001 cgaccggcac cgattttccg gatagtatcg cataccgttt tgtcttcaca ggcaccgcag
     9061 tgtccaccgg gtacacattt gtagatatcc acgccctttt cccgccagat tctttcctta
     9121 atccggcggc ctatttctcc cacttcttta ctgatctgat tcaattcctc gatatcttct
     9181 ttggttgtgg tcacgaatac gatctctacg gctttaacct tgggtaagat ctgcttaata
     9241 tgccaattaa gcactgaacc caacacatgg aaattaaagc cgttctttgc cgcatctttg
     9301 ctgattctgc accatatact ttcggctgtg cttcggatca tatacccttc gatcatctcg
     9361 gagacgttga ggttctgcag caggtaataa tagtcttctt cggtcaggtg ttcaccaccg
     9421 accataatga cttgaccgaa aggaagcttt ttaggagtat attcagtaat atccgaaccc
     9481 attaaggtga tccacccgtc cgtgatttga tgggggctat tcgtatagag agtcatcgag
     9541 catgagcctg cctccgggct gcccagctct acaagcacat cgttttttaa aacgatactt
     9601 gagccggttt tacgtccttg cccgggaact agccatgggt ttattgcagc gacgtcctga
     9661 aaacaggata gggtccaata attatcaact ttttgggtta aagcattctt atattgattt
     9721 aacttgccga aatattgact gaaaacggcc atgctcgtcc cctcctcctt cgcttcttag
     9781 agccatggaa ctcctatggt ttgattagcc ttttctctgc tctgtctctt gccaggagag
     9841 cagcccctaa ggcgccggcg atttgaggat taaaggtcag ctgatgaata cttaccccca
     9901 gctgcttctc cagacttttt gtcaacgctt cattccgggc gcagccacct gtgatgacta
     9961 catccgtttt aatcccaatt ttgtaggtca tggcatgaat tctgcgggca atggagtcat
    10021 gaattccggc ggcgatatct tctgccttga ccccattatt gatcatggtg accacttctg
    10081 attcggcaaa tacgctgcat tgcttcgtaa tattagctgg gttagctgaa tttaaagcga
    10141 gggttgacag ttcgctcatg gtgcaatcca gaactctggc catcgcctca aagaatctcc
    10201 cggttccggc agcacattta tcgttcattc cgaactcaag tacctttcct gcctcatcta
    10261 aggcaatgac tttacagtcc tgaccaccga tgtctacaac cgtccttacg tttggatgca
    10321 tccaatgggc tccgcgggcg tggcaggtga tctccgacat attatcctga atgaaggaga
    10381 ctcctgtcct tccatatccg gttcccacca catagtggat ctccgacttt accaggcctg
    10441 ctttgtccag agcttcctcc agtacctgct gagccgttat ttccggattt ctggccgatt
    10501 taacaacagc ccaggataaa atcttatccc cttttaatag gacagcttta ccggtcgctg
    10561 agcctaaatc acatccacat acaatcataa tttaatactc cctaatacaa tttaatgagc
    10621 ggcagattga atcctttggg ctcagtttgc cgctcatcgt ctttgttcct caatagaaat
    10681 tattatgatg acatgatctt tctatataag agtttatgta ctgctattct tgctccagcc
    10741 cgttgcttca aagaactcgg acatctgctg ctttacttta tccaagggtg tataccgctc
    10801 atcaaaaagg ctggtggtaa gacagaggag gggaacgttg aggctacggc agagttcctg
    10861 cataaagtga acacttccgg atacatcctt gtgtcccatg tgtcccggcc aaaagacgca
    10921 attgatagtg taatctttaa taatccttgt catatcttcg atcataacct caacggtacc
    10981 acgtccttgc ctgatcatgg gtacttcgtg caaggccctc cgggcaagtc cgtacaacat
    11041 ggtatcttcc gaggtggtat caatatgggt atacggggaa tagccctgat agtccatcac
    11101 cacattggct ccccattctt cggccagcca tggcgcaagc agatcacccc actgaggtgc
    11161 caagtccgcc cagagaatgc ggatttgttc gttaggaacg gctcctatac cagctttaac
    11221 tttcgcttcc gcatccataa tcatcatccg aattaattcc gtggctcggg gatctccgct
    11281 ggaaatgaat tgtgttagag tccagagcgg aacggaacct tggaaagaac cgtggggaca
    11341 aggagtcact cgtctcagtt cgttatactc cgcccatagt tcatattgag tgttggtctc
    11401 tgccacgact ttcctaagct tatccacgtc atacttttgc ccggtaatct ctaccaagaa
    11461 atgaatcaag cgctttagct cgccggcaaa atacataaaa tcttcgtctg ttgacccata
    11521 agccggatct aaaccaaatg ttggtacacc accccaatgc tcgctgcttt ggtagtactg
    11581 atgcagcatc aattccgcat cacaaggttc cagcatggaa atgatggctg taggcctggg
    11641 aaggagtttg ttttctatag cataagctcc aaaacggatc agggagcaga tgtcatcagg
    11701 cagagaaatt ttgtctgctt ctttaacatc gtacaagtcg gtaaaatatt cgtgcaataa
    11761 gatatcaaat accggaacga tgaagtggat gtccatagct gtgaggattt ctggagcgtt
    11821 cccgtaccaa gtggatacaa aaggtttgcc gttttcagca caatcaatgg ttcgttcatt
    11881 ggtttccata atcaagcgta aaaggccttc caggacagga ttccgttgtt ccgccggagc
    11941 ctgttccatc atgcctaaaa tcccgtttat gcgctccttg tattcatagg tacgctccac
    12001 acctgttttc gctgcgttcg tcatgctcat acctccccca gtgtctcaac aaaggcttga
    12061 actcttgttt taagttgtcc ggcattggtt agggcatatt ctgtttctaa cttgagataa
    12121 ggtaattttt cggttcttaa aatctcggcg atatcatttt gttcaaagcc ccatatatcg
    12181 cagaggagaa agcgcaggga gatgactccg tccacctgat actccctggc agtcttcctg
    12241 atgaagtcaa accgctcctg gaatgttccg tacagacggg gacagggcgg tttatcctcc
    12301 atgtgatacc gggcaagggc ggtcaatcca tcttccgttt cggagacatc gcaagcgatt
    12361 tccctggcac ccaaagccat cgtatcactc accaccattc cgccttggct ttccagaatt
    12421 ttcagcagct cgggattatc cagttctcca ccaatcagca ttaagcgggc attgggcttc
    12481 ttgccctcac ttatgcttag ttcatcgatc aactctgcca gcaaccggtt gtagcgggcc
    12541 accggcatga cggttccagc gatcataacg gtcagggtct ctgcaccgct taggggagga
    12601 ttttctcttt tctttaactc gtagagccga cgctggagct gccgtttttt attgtgcagc
    12661 ctaatagcct ctttcagctt gtcctcgctg atgacaagat taaaccgctt ttcgatgctt
    12721 gcttttaaag acacgagctc ttcacgatac cgttctgttt gttcttttcc tacttttttg
    12781 ggaagaacaa gaaaatggaa gcaaggattg ttttcgagag actgccaatt atcagaaatc
    12841 cgtcggatat gatcacaacc gttgaagttg atgactccat cgaggaaatc acattcacct
    12901 tttaatacga gttcaaaggt gtcacggacc agggaacaaa cgttatgggt gaaatatttg
    12961 tccgccatgg cagctccagg gctgccaatt cctcggatct tgtagggtaa caaacctgcg
    13021 gcagtgatca gctcttccgg aatataagaa taaaaatagc ctaccacttt accaccttgt
    13081 tgcttccacc cttggacttc cggattgttc aaggtactta cagcttgctt aaagatctcc
    13141 atagcattgg tctttagtgt attcaaaaaa tcactccctt tttacagaaa ttatttattt
    13201 gctacgaaaa agagtttaag tgttgtttaa gatatactga caagacatta ctcagacgat
    13261 cttgggtact tggttgtgta atcgatggca cgcaatatgt taagaagtgg ccatgttgct
    13321 ttgatcgggc acggcatgac cacttctttt taaaggacta gggtgactta ttttgcttta
    13381 atcaaagcat catttacagc ttccttgatg gcagcagagg aaaccgatgc tccggaaatc
    13441 ccatcaactt ctgtggactg ggcttcgaca atttttccgg ggagttggtc cacggccagt
    13501 gtcccaatac cctccgtttc accatgggaa gtaactttga cattggcgat cttgccgccg
    13561 gctatttcca cggcaacggc aatctcccca ccgattccat ttggactgat cccctcatag
    13621 gtaccatctt gatagccgct ttttttactg ctatcagcac cactctctgc actgcacccg
    13681 actacggata tcagacaagc aacgctcaaa atcattgcga caattttatt tatggctatt
    13741 tttttcattt tctgatttta cctcctttaa ttttatagtt tctgattatc ggattaactt
    13801 tcgtaaatgg acccggttat ggcatgtaaa gccgccaagc gggcaaagca ggtggttctt
    13861 ccatgagcta gtccaccata gtattgagga taggtattcg caaagaagcc gccactgtcg
    13921 ttcccggtta catacaaacc ctggatggga tcaccgtttt cattgatggc ttggatattg
    13981 gtattaattc taacgccatt aaaggtgcac aataaccagt tccccagagc aataccataa
    14041 aagggacctt gggcgacagg acgtagactt cccggatctt tgccgaagtc agcatcaaag
    14101 cccttcgccg cattctcatt atagcgtttc acggtagcgg ccaaagcgtc ggccggaagg
    14161 cccaattgct tagccaggtc ttccagggta tcggcctttt tcagcttacc gcttttgaga
    14221 gccggttcca tgtaagcctt atcaaattct tcttttgtct ggcatgggaa gacacccggc
    14281 agtacctcgg aattacgggc acccggagcg gcgactaccc gtgaacaaat ggtcgtatgg
    14341 aaggcattga cgtcttccca ataattgctg tcgaagatct ggaaccagat ttgcttgggt
    14401 tgtttgctgg cgccatggat tttagaatca tacggtgcct tttcattcat aaagcgctcg
    14461 ccgtgggtat tgaccgccag ccagggctgg cttcccggcc accacatatc atccagaccg
    14521 gaagtataag gttccccagt atgatggtcc aaatccacag cggctcggtc aaaggcaact
    14581 ccgccgccat gattgcgatc aatggcagct ccggcccaca tagccatctt aatgccatcg
    14641 ccgttatgtc cggcaccgcc cagattattg acaacgttat ctttgcagcg atagcgaagg
    14701 gcatccatca tctccgtatt cccagagtat ccgcctgtgg agataatcac tcctttagcc
    14761 gcattgatct ggatataggc gttatccttt ttacgctgaa caataatacc atttaccttt
    14821 ccgctgctgt cctgaagcag ttgcagggcg gtatgctcga aaaatttctg aacgcccatt
    14881 tctgtggcga tttccaccca gatgggattg gcaacttcgg accccatctt tttaggcccc
    14941 atttccaccc actcgccttt gtaagcacaa tgctcgccgc ggttatttgt cctgtacata
    15001 tcgcttttgt acatatcggt ctcaacgtgc atgctcacac ccttggcagc catctttttc
    15061 gaaaaccagt ccatggtcct ccctgagttg tctgcccata acttaattaa acgttgatcc
    15121 acttcataac ttgcataacg gcaaatatcg ttgacaatct cattcttttc tgcttcagta
    15181 aaggttatgc cgtatttttc cttaccgact ttggagttca gggcatgaat ttcaccggcc
    15241 cacataatag gtcctgcatt ttgctcgacc caagcgacct tagcgcccag atcagcggca
    15301 ctgacggcgg cgatgcaacc gccgttccct gcaccgacaa ccactacatc cacatcaaat
    15361 ttttctttaa tatccgtaat ggatgccggc tttttgaaat acgcttcatc ataccatttg
    15421 gtgctcttgg tgggagtacc ggtactggca ctatcagctg gagcaacggg gtcagaattt
    15481 cccgtgccga cactggcact ggagcagccg gtgagaatgc ctgttaaggc tacccctgca
    15541 gcggtagctg ttgcaccttt gagaaagtct ctccttgtaa aatgactcat tgaataagcg
    15601 cctccttaaa tcttttttca caaccttctt tattaatcta tcatatttca gaggagcagg
    15661 gtctgtccca taagttatat tgatataagt taaggttata acaatatgta tagctaagga
    15721 ccttttcaac cttctcctgt gaagaaattt gagccaggat gcaagtatcg gtattcactt
    15781 catgtgaggg gccattcgtg ctgcttgcag aagtctttaa ataaatggag ggcaggcttt
    15841 tcgttgttga tatgccaggc taagacaaag tccatgggaa ttttatcgct atcaatatcc
    15901 acataagtaa cagactgatg accggcaatt ttaaatgacc ttggaatagg cgcaactccc
    15961 atacctgccg aagccatggc gatggtcgtt tcatagaaat cagctaattt ggcgttttcc
    16021 atatcaaatc cggctttgcc caggcattca ataatgtatt ttaaacttct tgccgcacct
    16081 ttgttattgg tcatgataat tttttcgttt ttaacaagct caggtttgat ctggtcgtat
    16141 tgagctaaag ggctggactt tgaaacggcc aatgccgcaa aatcgcgaaa caagaaaatg
    16201 ctgtcaagta tggtaacgtc aagaatttcc gaccgttcgc tgaagacaac gtccaatttg
    16261 ccattgatca gatcaaggat caacggcccc cagtctccca cgaccacatc aatttcaata
    16321 tgtgggtgtc tcttatggaa ttcttgaacc acatcgttca tttttgccca ctccgtgggg
    16381 ccatgataac caatggacag atgattatat tccgatatgc cgattttttt ggcttcaatt
    16441 tttgtattct cataacaatc gagaatatag gcaaagttct tttggacgga ctttcctgct
    16501 gaagtcaact ccactttatg gcgagtccga ttgaataatt taaccccaaa atcttcttca
    16561 agcgcactga ttttcttgct cattgccggt tgggtaatga acatttcttt tgcggcgagg
    16621 gacaggttta agtttttagc aacacttaaa aagcattgta catcaaaaaa atccatagtc
    16681 tcacctacat atttatagta tctgccattg gaccttcccc tgttttgctg tatctaaaaa
    16741 gtgtgcaaat agggataatc tatttcgcac tcagccagtt tttttatagt ttatctaaca
    16801 gcgcttcaat ctgatcttcc gttttctgtt tatccatttg aaatacaatg accacaatgc
    16861 tcacatgaat agttgtggac gatacttccc tgctgcttac ttcaccgcca gtagttgata
    16921 atacgaaagc ggggccgctg acctcaatgg aggctttaat gtgaccgata ataccatccc
    16981 gtttttctac ccactctgcg aacatgccca tttcatcacg gagctttttt ttaacaacct
    17041 ctaaatctcc gataatattt ctgtttcccg aacacactaa cgcatcatta tgtcgatgcg
    17101 actctatgtt atcacttcgt tgttctgttt ggtggtgctg gtggtcatga cagcattctt
    17161 cagtttcgtt gccattcatt ttcatttaat caccccattt cacttatcat atcctgccag
    17221 cattgaacag gtatttcttc cttcgcagat atgcaaataa cctttgcggc tctggaatat
    17281 tcttggacgc ttatttttac ttgagcaagt tcactggcat ttacaagatc ttttttattc
    17341 accaatactt gcgaactctc ttcaagttgt cccgctacca gcggttccat tgcacttact
    17401 aatcttctcc atctctttgc atctacaatg gttaatatat aggccccaac tccaatagcc
    17461 tcaaagattg ctttgctaat gcttccggga aaggcaacac cagttgcttc aataatcagc
    17521 caggcaggat tcagttcgtt ttgcattttt ttaacgcttg aaaccagctc tcctgccaaa
    17581 gtgcagcaaa cgcaaccggc aaagagattt tcaacagtga atccagcgtt ggcaagaatt
    17641 ttatcatcga ttcctaccgt gccgatttcg ttttccagaa ttgctacttt aatctcagac
    17701 ttattatctc tttcctgagt gattagatac tttgccaact gcaacagtac acttgttttt
    17761 cctgaaccca aaaagccacc caaaattatt attttcacat gcattctcct tctcagatat
    17821 atcagtccca agattttgcc tgccaaattc atgaaataaa caagctctgc taaaaaacgc
    17881 atacaacaat acagtcccgg aaaaatcaga ctaagaacct aagtcacaat ttttccggga
    17941 catacgagat taagggaata agtaaagttg aaaatcacta tgaaccccaa ctgagtaagg
    18001 cgtcggatta attacacgtt gactaattcc tttgctttga ttgctgcgct gcctgcatcc
    18061 ccagcatagc cgtcggcacc gatttcatta gcatacgcct gcgttacagg agccccaccg
    18121 acaataatct taaatccggt aagtccgctc tctttgatgg tttgaactgc ttccttcaga
    18181 gcgggcatag ttgtcgtaag aagtcctgaa caagccacta aagttacgtt cccattttct
    18241 ttaattgcct ctacccattt agaagcaggg acatctacac caagatcaac catatcaaat
    18301 cctgcgcttt ctatcatcat gccaaccaga tttttcccga tatcatgaag atctcctgct
    18361 accgtcccga taacacaagt acccaaagaa gctgatgcat cacctgtcag atgcggcttt
    18421 agaacctcaa cgcctttggc cattgctttg gcggccagca gcatttccgg cacataaatt
    18481 tctccggcgg aaaatttgtc cccaaccaca ctcattgaat caaccattgc ctgaagaagt
    18541 tctttcgcag tatttccttc atccaatgct gcttgtacca gccccggaac aattttggtt
    18601 tttcccatct ccaccgatat tttgacttca tttactttcg ccatgactaa atcctcccat
    18661 acttttaaaa tatatatccg cattcatgtc ggttattttt tttgaccgaa tcgtccctca
    18721 cgaaaggccc caatgtattc catacaatat tcatcctgcc ccagcagggc ttccgttgca
    18781 tggatcatgc cgatcaaatc ctgattggta gggtcgataa tgccgctatc catgcccgca
    18841 ttcattgcga gcacacaaaa tgcctgatta acaagtttgc gagccggcag gttaaatgaa
    18901 atgttgctga atccaccggt gacatggata tccggatatt gacgcttaat ttctctgatg
    18961 acatccatga tcatattgat gccctcttcc gaagtacaga gcatttcgac aagcgggtcg
    19021 atgtgcagac gggacggcgc tatattaaat tctttagccc ttttcatgat gtgagcaaac
    19081 acttcaaggc gtttctcagc ggttttagga ataccggtgt cgtcgcagag caatgcaaca
    19141 cattcccatt gggtatcggc aatgaccgga aatactacgt caatcttatc tccttcgccg
    19201 gatacagagt taataagccc cgatcgcttg caaaatttga tggcatcgac gcaggtctgg
    19261 gcttgtggac tgtcaataca aataggggta tcactgactt cctgcactaa gtcaatcagc
    19321 cacttcaggg tttcgagttc gatgcttgta tccgtggatg cgcagacatc aataaaatct
    19381 gcacctgcat tggattggat tttggcaagg ttgtgaataa aagcaacatc cttttcggcg
    19441 atcgctttag ccaccgaagg aatagcaccg ttgatttttt ctccgatgat gatcattctc
    19501 attctccctt ttaatacttt acaaactaat taaagtcgga aacaataaat gtgcaaattc
    19561 gttctgttac agttacaagc cggctagtct gtaagtcaga gcaataaaca gaaaaacatc
    19621 cgtttggatt tgaacattta aatatttgga attgattgac tttattgtat gcccaatagg
    19681 cttgatagta aattagacac attatttact tttaaggcga ttaatctata catcatgtag
    19741 tatggtttaa tataaagcca cactatatca ttcatagaat aaaagaaata tgcccggaaa
    19801 atcgaagcaa catcaatttc caggcatatt tttatgtcag gttaatccgc attataaaca
    19861 ttctatcccc gtctatcagc tttataaaaa agtctgatag atatttttat atagagaatg
    19921 tcatcagggt ccttgaaatt tatgccggcc aactctttaa ttctctctaa tcgattgacc
    19981 atcgtggcac gatgaataaa taaatctttt gcagtcttga ctgcgttcat ttgattgtcc
    20041 aggtaaacct ttaatgtgtg aaggtaatca ctcgaattcg ccctatcgta gctatccagg
    20101 ccgatgattt taggggaaca cagaaattgt ccgtccagtt cttcagttag cttggattcc
    20161 atataaaaaa ggacaatatc tgaaaattta taataccaac gggaagggaa ttggtctaag
    20221 ccaattctca agctgatttt agcctgcaca taatgagctt gaatatccac gatactggta
    20281 aaaacattac tgtatcccac tcggaaataa ccgtcccgca gagtctctaa atagaccgag
    20341 ttgaaacatt ctcccgaacc attgtaatac tccaaattga caatgcaaac aattttacgt
    20401 tcatactcaa aggcacagca gcctttgaaa tcgcgattga tcatctgaca ataatacggg
    20461 attgtccggt tatagtaatc cctatcactc ggcattatac tggcgcacag gaaaggcccg
    20521 tcataattcc agccatgctg tgaaacactg tttttcaagc gccagctttc aatcgattcg
    20581 ccgctgataa gggcggagaa aatctcaacc atatgttctc gcggcataat gtcaccactg
    20641 tagccggcca ggtcgtatac aagttgaata aaggatgtga aaaaatgcaa aagcccggct
    20701 tcataacccc gaaaagtact gcgatcctcg gcgattacga ctcggcatac aaaatcatcc
    20761 tggaagaaca cattcataca aataacccgg caaatgaaaa tactgggttc atagataaaa
    20821 ggttccctca tgttttttac attggaataa ataagatcat tcttaaaaaa ttccacatgc
    20881 tccgtcgaga gcctgccatg gctgtcaggc tgcttaatac cagaaatctc acacatatga
    20941 atcgtactgt ttgattgacc gatcaacttg aattcagcgt tcatcacaac cagttcattg
    21001 tttaaaaact gcgccatttg ctcaaccagg tattgaatgc tttttccctt attaaccgcc
    21061 tcatggagtc taagttccag agaattatat tcaaaaaaaa tccggttaac ttcgttggac
    21121 agctcggcta ctttcttgga ctgatcaagt acaagtaata taagcggcga tttagtatac
    21181 aattctgcag gcataccgat gcagatcagt gccgcccctt cttgcacgat catctcttcc
    21241 ggtaaattct cagcatgagc aatgttgaga accccggcat ttaaaacctt cgtactctcg
    21301 caatacattt ccgctctctc caaattaaag ggaatatcgg tattcagata gtttttataa
    21361 ataatatctc cggagattcc atcttctatg attcccatac agagcttcat gacagtccct
    21421 cccacaatgt cctatacaca ttgtatataa tatccgctta acaatcaatg tttctgtata
    21481 atttacttcg ttattccaat gcattaagct tgacttaatt atttatatct ttatcaagct
    21541 atacaatgta tatagcacgc ataatatcat tcgaacattt ttaaggaggg ttttgtaatg
    21601 accattacaa aaagagaaaa ttatcttatg gcaatgaacc atgaaaagcc cctttggacg
    21661 cccgtttttt tgtatgacaa cgctgccgtc ggtttttgtg ccgcacctgg cccctggttt
    21721 gagaaaggtc cggtcggcgg tggctacgac ggattcgggg tgcgctggat tactcccgaa
    21781 tcggggagcg gcacaccaat tcccgctccc aatgaatata ttcttacttc ggaaacggtt
    21841 caggactgga aaaaacttgt caagttcccc aatgtcaatg atttcgactg ggaagattat
    21901 gctaaggccg aattgacacc ttacaacagg aacgaagtga cgatcgattt cggcagcgga
    21961 aatggtccct tcgagcgtct ggctgctctg atgggtttcg aagaagcact cattgcactt
    22021 ctcgaagaac ctgaagcctg tgatgaattg atcggagcta ttgttgacta taagatcgaa
    22081 gttgctgaaa aagtggcaaa atactacaaa gctgattatt ttacaaatta tgatgatatt
    22141 gctacggaac gaggtttgtt catgtctccg agcactttcc gtaaaatcat caaaccccat
    22201 accaagcgca tgtacgatgc tataagatct ttgggcatgc agcccataca acacacctgc
    22261 ggctatgctc aggacgtcat cgaggatttc atcgagatgg gcgctcaggc gtggacctct
    22321 gtgcagccaa ctaatgatat tgtcgcgctt cagaaaaaat atggcgataa aatttccttt
    22381 attggcggtt ttaataccaa tggccgggcg gcacaggtgg acgccaccga tgaagaaatt
    22441 gtgaaagagg tctatcgcac ccttgacacc tatggcccgc agggaagttt cattttcttt
    22501 gcctataagc ttgcaaacac gttggatatg aacaagttta tggctgaatg catgcgagct
    22561 attggcccag caatcgctcg ttcaatggag aatgccgggc ttagccaagt ttaa
//
