LOCUS       NZ_KB899604.1          15228 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KB899604.1 Megamonas rupellensis DSM 19944
            F553DRAFT_scaffold00039.39, whole genome shotgun sequence.
ACCESSION   NZ_KB899604
VERSION     NZ_KB899604.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:53:22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15228
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..861
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.1e-11, bitscore:
                     33.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="PVNISGKYFKIIPYGVDKETERIDYDELERLAKEHQPKLIVGGAS
                     AYSRIIDFERMAQIAKSVGAYFMVDMAHIAGLVAAGLHPSPVPYADVVTTTTHKTLRGP
                     RGGLILCRDAEFGKQFNKAIFPGIQGGPLMHVVAAKAVTFKEALSDEFKVYQQQVLDNA
                     KALSDELVKKGFRIVSGGTDNHLMLVDLRSKNITGKEAQFLLDEIGITANRNTIPFEPL
                     SPFVTSGIRLGTPALTTRGLKEEDIREVADIIADVIENREDSAVIEAAKAKVQAICKKF
                     PLYEA"
     protocluster    1..15228
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[944:5228]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      945..5228
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..15228
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15228
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             945..2036
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_2"
                     /sec_met_domain="GCV_T (E-value: 2.3e-95, bitscore: 308.6,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 6.4e-25, bitscore: 76.8,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLLKTPLYEEHLKCHGKMVEFAGYSLPVQYATGVIKEHLAVRTA
                     CGLFDVSHMGEIICEGEDALANINMLLSNDYTDLDINHARYSPMCNEQGGVVDDLIVYK
                     QHEHKYFIVVNAANKDKDFAWMKAHAFGDVKFSDVSADYAQLALQGPKSEHILAQVTDE
                     KNIPQKYYTCIFDAKIDDIDCIISRTGYTGEDGFEIYVASKYAPAIWNLLLENGKEDGL
                     IPCGLGARDTLRLEAAMPLYGHEMNDEISPKEAGLGIFVKMDKPDFIGKSALEQKGAPT
                     RRRVGLKVTGKGIIREAQDVYIDGEKIGVTTSGTHCPYLKQAVALAIVDVAHKDVGTKV
                     QVDVRGRMVEAEIVKLPFYKRSK"
     CDS             2075..2455
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_3"
                     /sec_met_domain="GCV_H (E-value: 2.6e-45, bitscore: 143.1,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFPEELLYVKSHEWVQKQEDGTYLIGITDYAQDALGDLVFVNLP
                     EEGDEVVKGETFADVESVKAVSDVFSPVSATIEAVNEELADDPALINSDPYGAWFIKVS
                     NLTDHEDLLSAKEYEKYVQTLD"
     CDS             2476..3789
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: Aminotran_5"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_4"
                     /sec_met_domain="Aminotran_5 (E-value: 8.8e-09, bitscore:
                     24.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 1.4e-139, bitscore: 455.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTYVVNSKKEQQELLTRCGLNSFVDLYKDIPEEVLLKDGLNLPK
                     GLAELEVKRKFEDLADKNKVYKYIFRGAGAYNHYIPSVVKAIASKEEFVTAYTPYQAEI
                     SQGILQAIFEFQTMICELTGMQIANASVYDGATAAAEATAMCYERKKANTVYVSATTNP
                     QVIEVIKTYSFGHDIKVELVPEKNGVTDIEALKTMIDNEASCFYVQQPNYLGNIEDLVA
                     LGEVVHKVKAKYIVGANPIALAVLQTPAQAGADIVVGEAQPLGLPLGFGGPYLGFMATT
                     DKMMRKLPGRLVGQTVDVDGKRAFVLTLQAREQHIRREKASSNICSNQQWCALVASIYL
                     ATMGAKGLVEVAEQSVAKAHYLAEELSKAGLTLKYQQPYFHEFVTVSAKNTQDIMDKLA
                     QNNILGGLPLNEREILWCATEMNTKEEIDKLVELVKVV"
     CDS             3792..5228
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_5"
                     /sec_met_domain="GDC-P (E-value: 2.5e-12, bitscore: 36.0,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLIFEQSTQNHQCSILPPCDVPKVELPIKRQESLNLPELSENEI
                     SRHYTQLAENVHGVNNGFYPLGSCTMKYNPKIDEEVASFKGFTNIHPLQDTKTVQGALE
                     AISLANDYLCEITGMDKMTFQPAAGAHGEFSGLLLIKAYHKSRNDEKRYKIIVPDSAHG
                     TNPASASMVNYDVISVPSSSDGCVDIEALKAVLAKEGENIAGLMLTNPNTVGIFDKNIL
                     EITKLIHDVGGLCYYDGANLNAVMGWARPGDMGFDVVHLNLHKTFATPHGGGGPGSGPI
                     GCKAFLQEFLPGYQVVQKDDYFDLVRYEKSYGMVKEFYGHFLVVLKALAYIMTLGKEGI
                     SEASANAVLNANYMKQELSDTFNMAYDGICMHEFVMSLEQLKHDYNVSALDVAKAMLDY
                     GIHPPTMYFPLIVHEALMVEPTETEGKAQMDEAIKIYKEIYKTAIENPDIMHEMPLNTV
                     VRRLDEVLAARKPILRYQAE"
     CDS             5235..6218
                     /locus_tag="ctg39_6"
                     /transl_table=11
                     /translation="MINSIKIVRGDGFNPYYNLAQEEYLTTTVNKGELIIYLWQNKHTI
                     VIGRNQNAWQECHVEKFIQDGGKIARRLSGGGAVYHDLGNLNFTFCVRKEDYDIDRQLS
                     VILTAVQALGIKAEKTGRNDITIEQKKFSGNAFYKQGDFCYHHGTLLLSVDSEQMLKFL
                     NVDKAKLQSKGVDSVKSRVTNLKEYNADITVESMCKQIKISAEKIYNCLAVDYVINSVD
                     KLKINELMQKFSDWDWIFGRKIQFTNHLQRRFSWGNVEFYIYVDKGRVKDIEIYSDAME
                     QKFILSLKEALKDCLYIKRNIIERIENLTEDKIMSKDLITLIQDDL"
     CDS             6240..7601
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_7"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.7e-74, bitscore:
                     240.4, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 2.7e-38, bitscore:
                     120.5, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENFDLAIIGAGPAGYEAAVFAAKQGLKTALIEKSELGGTCLNNG
                     CIPTKTLLHTADLYREMTNQADIIGLDYQALSFDMKKMQLHKQDVIQKLREGIAKLMKM
                     HKVTIIKGCAKIVGEHEIAIQSDEKVENIEAKNILIATGSVPAMPPIKGAELTINSDEL
                     LNDENVYEQIAIIGGGVIGIEFAFLYASLGKRVIILEALDRILANMDKEFAQSLKMLLS
                     KRNVEIQTKALVQEISYNEGTKKYNCKYLQKDAEYIISADKVLMAVGRRAYTQNLFADN
                     LSIETDRGKIKVNENYQTNIENIYASGDVIGGIQLAHVATAEAINAVCHMLGRAPIYNM
                     KLIPSCIYTNPEIASVGMTLDEAKAQGINVKTIKYPMGANGKTVLSLQERGFIKIIVDK
                     KTDCILGAQMMCAHATDMISQFTQAIQQELTLVDLQKIIFPHPTFNEAIGKAVE"
     CDS             complement(7643..8812)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_8"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4e-75, bitscore:
                     242.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDWNKNLATTVQHTKQSGIRRFFDIASTMEDVISLGIGEPDFVT
                     PWTIRESCIYGLERGYTAYTSNKGLYELRHAITHMYERDFQVKYNPNDEVLITVGVSEA
                     VDLAMRAILNPNDEILIPEPCYVSYAACATLVGAKAIAVPTKSENEFKVTPEDLEKHIT
                     PKTKALLIGYPNNPTGTILEYDELLAIANFAQKHNLIVISDEIYGDLTYGERKHICFSA
                     LPDMKERSIILNGFSKAYAMTGWRLGYALAPKPVIDAMNKIHQYTMICAPITAQIAGLE
                     AIRNGQKHMKKMVAEYDRRRRLIYEGFTSMGLKCFEPKGAFYIFPDISSTGLSSEEFAE
                     QLLLRQHVAVVPGTAFGECGKGFIRASYATSVDNISGALARIKNFLDNL"
     CDS             complement(8809..9288)
                     /locus_tag="ctg39_9"
                     /transl_table=11
                     /translation="MRELLELLEHDGRRSIKELATMLGRSEYEIEEQMKKLEKEKIILG
                     YNTMIDWEKYGDDSVSAMIEVNVTPQREFGFDAIAERIYRFDEVKTVYLMSGSFDLLVI
                     IEGKSLKNVADFVARRLSTIEGVTSTRSHFMLKPYKKDGIIIDDKETDHRLVVSP"
     CDS             complement(9610..10608)
                     /locus_tag="ctg39_10"
                     /transl_table=11
                     /translation="MLEQASILIFIVIALALIFDFVNGFHDTANAIATCVSTRAVSPAV
                     AIIMSAILNFAGAMISTGVAKTIGGDIVQSASMVNEVIIIAALAGAIIWNLITWWFGMP
                     SSSSHALVGGIIGAVIISVGFMGLNGYGILKIFLSLVLSPLAAMAIGWIILHIIFAICH
                     SMRPATVNDNCNRLQVISAALMAFAHGSNDAQKSMGIITLALLSGGYIGALEVPTFVKI
                     SCAFAMALGTSFGGWKIIRTVGGKIFRMQPVHGFSADLNSAVVIFGATLLHLPVSTTHV
                     VSGSIMGVGAAQRIKAVHWDVARQMLVAWLMTIPCTAILSAIVYLILHLFI"
     CDS             complement(10601..11230)
                     /locus_tag="ctg39_11"
                     /transl_table=11
                     /translation="MFDIGNKHYEFFDMLNQHAKYFNQGSKIMYDVMINYDTAQTKMEE
                     IKTVEKQADLVTAETVQKLNQVFITPIDREDIFALSYGLDDGVDNIHGSLERVIMYEAG
                     QPKTDGPAKLSKLLIQATEELVKATALLKDIRKNHNEILECTNRILTYESQGDTLYRSE
                     MSSLFKTEKDPITLVKWKDILQCLEDTLDQTKHISDTLKGVVMKYA"
ORIGIN
        1 cctgtaaata tttctggtaa atattttaaa attattcctt atggtgtaga taaagaaact
       61 gaacgcattg attatgatga attagaaaga ttagcaaaag aacatcaacc aaaattaatc
      121 gttggtggag ctagtgctta ttctagaatt atcgattttg aacgcatggc acagattgca
      181 aaatctgtag gcgcatattt catggtagat atggcacata ttgcaggttt agtagcagca
      241 ggacttcatc caagcccagt gccatatgca gatgtagtaa caacaactac acataaaaca
      301 cttagaggac ctcgtggtgg tttaatcctc tgtcgtgatg cagaatttgg caaacaattc
      361 aataaagcaa ttttccctgg tattcaaggt ggtccattga tgcacgtagt ggcagcaaaa
      421 gcagtaacat ttaaagaagc gctaagtgat gaatttaaag tttatcaaca acaagtttta
      481 gataatgcaa aagccctatc agatgaactt gtgaaaaaag gatttagaat tgtatcaggt
      541 ggtacagata atcatttaat gctggtagat ttgcgctcta aaaatatcac aggtaaagaa
      601 gcacaattct tattagatga aataggtatt acagcaaata gaaacacaat tccatttgaa
      661 ccactaagcc catttgtaac aagtggtatt cgcctaggaa caccagcact tacaactaga
      721 ggattaaaag aagaagatat ccgtgaggta gcagatatca ttgctgatgt tatcgaaaat
      781 cgtgaagata gcgctgttat tgaagcagca aaagcaaaag ttcaagctat ttgtaagaaa
      841 ttcccattat atgaagctta aaatatcggt ttatcagttg gacaattaag tatataaaaa
      901 catcaaattt tagtgtcggt aataattaca aggagggaat gtatatggat ttattaaaaa
      961 caccattata tgaagaacat cttaaatgtc atggtaaaat ggtggaattt gcagggtata
     1021 gtttgcctgt ccaatatgct acaggagtaa ttaaagaaca tttagcagtg cgtacagctt
     1081 gtggcttatt tgatgtatca catatgggtg aaataatttg tgaaggtgaa gatgctctag
     1141 caaatataaa tatgttatta tccaatgatt atacagattt agatattaat catgctcgct
     1201 atagtccaat gtgcaacgaa caaggtggcg tagttgatga tttgatcgta tataaacagc
     1261 atgaacataa atattttatt gtagtcaatg ctgctaataa agataaagat tttgcatgga
     1321 tgaaagcaca tgcttttggt gatgtaaaat ttagtgatgt ttcagcagat tatgctcagt
     1381 tagcattaca aggtccaaaa agtgaacata ttttagctca agttactgat gaaaaaaata
     1441 ttccacaaaa atattacact tgtatttttg acgctaagat tgatgatatt gattgcatta
     1501 tttctcgcac aggatataca ggcgaagatg gttttgaaat ctatgtagct agtaaatatg
     1561 ctccagctat ttggaattta ttattagaaa atggcaaaga agatggctta atcccttgtg
     1621 gtttaggtgc aagagatact ttgcgtttag aagctgcaat gccactttat ggtcatgaaa
     1681 tgaatgatga aatttctcca aaagaagcag gcttaggcat ttttgtgaaa atggataaac
     1741 cagactttat cggtaagagt gcattagaac aaaaaggtgc accaactaga cgtcgtgtag
     1801 gcttgaaagt tacaggaaaa ggaattatta gagaagcaca agatgtttat attgatggag
     1861 aaaaaatcgg tgttactaca tcaggtacac attgtccata tttaaaacaa gcagtggctt
     1921 tagctattgt agatgtagca cataaagatg taggtacaaa agtacaagtt gatgtacgtg
     1981 gtcgtatggt tgaagcggaa atcgttaaat taccatttta taaaagaagt aaataaagaa
     2041 aaataaattt ataaattttt aggaggaata aattatgaac tttccagaag aattattata
     2101 tgtaaaatct catgaatggg tacaaaaaca agaagatgga acttatttaa tcggtattac
     2161 agattatgct caagatgcac tcggtgattt agtttttgtt aatttaccag aagaaggcga
     2221 tgaagtagtt aaaggtgaaa cttttgctga tgtagagtct gtaaaagctg tatctgatgt
     2281 attttctcct gttagtgcta ctattgaagc tgttaatgaa gaattagctg atgacccagc
     2341 acttattaat agtgatcctt atggtgcatg gtttatcaaa gttagcaatt taactgatca
     2401 tgaagattta ttaagtgcca aagaatatga aaaatatgta caaactctcg attaaataat
     2461 tattgaggtg attttatggg aacatatgta gtcaatagta aaaaagaaca gcaggaatta
     2521 ttaactagat gtggtcttaa ttctttcgtg gatttatata aagatattcc cgaagaagtg
     2581 ttattaaaag atggtttaaa tttaccaaaa ggcttagctg aacttgaagt taaaagaaaa
     2641 tttgaagatt tagctgataa aaataaagtt tataaatata tattccgcgg agctggtgcg
     2701 tataatcatt acattccatc ggtggtaaaa gctattgcaa gtaaagaaga atttgtaaca
     2761 gcatatacac catatcaggc ggaaataagt cagggaatat tacaggctat atttgaattt
     2821 cagactatga tttgtgaatt aactggtatg caaatagcaa atgcttctgt ttatgatgga
     2881 gcaacggcag cagcagaagc aacagctatg tgttatgaac gcaaaaaagc taatactgtt
     2941 tatgtatcag caactactaa tccgcaagtg atagaagtta ttaaaacgta tagttttggt
     3001 catgatataa aagttgaatt agtgccagaa aaaaatggcg ttactgatat cgaagcatta
     3061 aaaacaatga tagataatga agctagttgt ttttatgtgc aacaaccaaa ttatcttggt
     3121 aatattgaag accttgtagc acttggtgaa gtagtgcata aggtaaaagc aaaatatatt
     3181 gtaggagcta atccaatagc tttggcagta ttgcaaactc cagcacaagc aggtgctgat
     3241 attgtagtag gagaagctca accacttggt ttaccacttg gttttggcgg cccatattta
     3301 ggatttatgg cgactactga taaaatgatg cgcaaattgc caggcagatt agttggtcaa
     3361 actgttgatg ttgatggaaa aagagctttc gtacttacat tgcaggcaag agaacaacat
     3421 attcgcagag aaaaagctag ttctaatatc tgttctaatc agcagtggtg tgcattagta
     3481 gcttcaattt atcttgcaac tatgggtgct aaaggtttag ttgaagttgc agaacaatca
     3541 gtagctaaag ctcattattt agcagaagaa ttatcaaaag caggtttgac tttaaaatat
     3601 cagcaaccat atttccatga atttgttact gtttctgcta aaaatacaca agatattatg
     3661 gataaattag ctcaaaataa tattttaggt ggattgccac taaatgaacg agaaatatta
     3721 tggtgtgcta cagaaatgaa tactaaagaa gaaattgata aattagttga attagtaaag
     3781 gtggtgtaga tatgaattta atttttgaac aaagtacaca aaatcatcaa tgtagtattt
     3841 taccgccttg tgatgttccc aaagtagaat tgcctataaa acgtcaagag agtttgaatt
     3901 taccagagct atctgaaaat gaaatcagtc gtcattatac gcaattagca gaaaatgtgc
     3961 atggtgtaaa taatggtttt tatcctttag gttcttgcac tatgaaatac aatcctaaaa
     4021 ttgatgaaga agtagcaagt ttcaaaggtt ttactaatat tcacccattg caagatacaa
     4081 agactgtaca aggcgcatta gaagcaattt ctttggctaa tgattattta tgtgaaataa
     4141 ctggtatgga taaaatgact ttccaaccag cagctggcgc gcatggtgaa ttttccggat
     4201 tattattaat caaagcgtat cataagagca gaaatgatga aaaacgttat aaaataattg
     4261 ttcctgattc tgcacatggc acaaatccag caagtgcttc tatggtaaat tatgatgtta
     4321 tttctgttcc atcatctagt gatggttgtg ttgatataga agcattgaaa gctgtattgg
     4381 ctaaagaagg cgaaaatatc gcaggtttga tgttaactaa tccaaataca gttggtattt
     4441 ttgataaaaa tatcttagaa attaccaaat tgatacatga tgtaggcgga ttatgttatt
     4501 atgatggggc aaatttaaat gctgtaatgg gttgggctcg tccaggtgat atgggctttg
     4561 atgtagtaca tcttaatttg cataaaacat ttgcaactcc acatggtggc ggtggcccag
     4621 gaagtggccc tattggttgt aaagcatttt tacaagaatt tttaccagga tatcaagtag
     4681 tgcaaaaaga tgattatttt gatttagtgc gctatgaaaa atcatatggt atggtaaaag
     4741 aattttatgg tcatttcctc gtagtattga aagcattagc ttatattatg actttaggca
     4801 aagaaggcat cagtgaagct tcggcaaatg ctgtactcaa tgctaattat atgaaacaag
     4861 aactttcaga tacttttaat atggcttatg atggcatttg tatgcacgaa tttgtaatga
     4921 gcttagaaca attgaaacat gattataatg tatctgcttt agatgtagca aaagctatgt
     4981 tagattatgg aattcatcca ccaacaatgt acttcccatt aattgtgcat gaagcattga
     5041 tggtagaacc tacagaaaca gaaggcaagg cacagatgga cgaagcgatt aaaatttata
     5101 aagaaattta taaaactgcg atagaaaatc cagatattat gcatgaaatg ccacttaata
     5161 ctgtagtgcg tcgtttagat gaagttttag ctgcaagaaa accaatatta cgctatcagg
     5221 cagagtgatt aattatgata aatagtataa aaattgtaag aggtgatggc tttaatccct
     5281 attataattt agctcaagaa gaatatttga ctactactgt aaataaaggt gaattgataa
     5341 tttatctatg gcaaaataag cacaccattg tgattggcag aaatcaaaat gcttggcaag
     5401 aatgtcatgt agaaaagttt attcaagatg gtggaaaaat agctcgccgt ttatctggtg
     5461 gcggtgctgt ctatcatgat ttgggaaatt tgaatttcac tttttgtgtg agaaaagaag
     5521 attatgatat agatagacaa ttatccgtaa ttttgacggc tgtacaagct ttaggaatta
     5581 aagcagaaaa aacaggtcgc aatgatataa ctattgagca aaagaagttt tctggaaatg
     5641 ctttttataa acaaggagat ttttgttatc atcatgggac tttattacta tcggtagata
     5701 gtgaacaaat gctgaaattc ttaaatgtag ataaagctaa attacaatca aaaggcgtgg
     5761 attctgtaaa atcacgtgta acaaatttaa aagaatataa tgctgatatt acagtagagt
     5821 caatgtgtaa gcagataaaa atatccgcag agaaaattta taattgctta gctgtggatt
     5881 atgtgattaa ttctgttgat aaattaaaga taaatgaatt aatgcaaaaa tttagcgact
     5941 gggattggat ttttggacgg aaaatacaat ttacaaatca tttgcaaaga cgtttctcat
     6001 ggggaaatgt ggaattttat atttatgtag ataaaggtag agtcaaggat atagagatat
     6061 attctgacgc tatggagcaa aaatttattt tatcattgaa agaagcatta aaagattgtt
     6121 tgtatataaa aagaaatata attgagcgga tagaaaattt aactgaagat aaaattatga
     6181 gtaaagattt aataacttta attcaagatg atttgtaaat tataaaggtg tggtgattta
     6241 tggaaaattt tgatttagca ataattgggg caggtccagc aggatatgaa gcagcagttt
     6301 ttgctgctaa acaaggattg aaaacagctc taattgaaaa atcagagctt ggtggaactt
     6361 gtttgaataa tggttgtata cccacaaaaa cattattgca tacggctgat ttatatcgtg
     6421 agatgactaa tcaagcggac ataataggat tagattatca agcattatcc tttgatatga
     6481 aaaaaatgca attgcataag caagatgtga tacaaaaact tcgtgaaggc atagctaaat
     6541 tgatgaaaat gcataaagta acgataatca aaggctgtgc taagattgtt ggcgaacatg
     6601 agatagcaat tcaaagtgat gaaaaagtag aaaatattga agctaaaaat attttaatcg
     6661 ccacgggttc agtgccagct atgcctccaa taaaaggtgc tgaattgact ataaatagcg
     6721 atgaattatt aaatgatgaa aatgtatatg agcaaatagc tattattggc ggtggcgtta
     6781 ttggtattga atttgctttt ttatatgctt ccttaggaaa aagagtcatt attttagaag
     6841 cattagatag aattttagct aatatggata aagaatttgc acaaagctta aaaatgttat
     6901 tgagtaaacg caatgtggaa attcaaacaa aagcattagt ccaagaaata agctataacg
     6961 aaggaacaaa gaaatataat tgtaagtatc tacaaaaaga tgcagaatat atcatatcag
     7021 cagataaagt attgatggct gtaggtagaa gagcatatac tcaaaatctt tttgctgata
     7081 atctatcaat agaaactgat agaggtaaga taaaagtaaa tgaaaattac caaacaaata
     7141 tagaaaatat ctatgctagt ggagatgtta ttggtggtat acaattagct catgttgcta
     7201 cagcagaagc aataaatgca gtttgtcata tgttaggcag agcgccaatt tataatatga
     7261 aattaatacc tagttgtatt tatactaatc cagaaatagc ctctgtaggt atgactcttg
     7321 atgaagcgaa agctcaagga attaatgtaa aaaccataaa atatcctatg ggtgctaatg
     7381 gtaaaactgt attatcctta caagagagag gttttataaa aataatagtg gataaaaaaa
     7441 ctgattgtat tttgggagca caaatgatgt gtgctcatgc tacagatatg attagtcaat
     7501 ttacacaagc tattcaacaa gaattaacgc tagtagacct acagaaaata atattcccac
     7561 acccaacatt taatgaagct attggtaaag ctgtagaata ataaaaaagc tgatgtaatt
     7621 taatttacat cagctttttt ctttataaat tatctaagaa attttttatg cgagcaagag
     7681 caccgcttat attatctaca gaagtagcat aagaagctct aataaatcct ttaccacatt
     7741 caccaaaagc agtgccagga actactgcta catgttgacg gagaagtaat tgttcagcga
     7801 attcttcaga agaaagacca gtgctagaaa tatcagggaa aatataaaat gctcctttag
     7861 gttcaaagca ttttaatccc atgctagtaa agccttcata gattaaacga cgacggcggt
     7921 catattcagc taccattttt ttcatatgct tttgaccatt gcgaattgct tcaagtccag
     7981 ctatttgagc tgttattggt gcgcaaatca tagtgtattg atgaatttta ttcatagcat
     8041 caattacagg ttttggtgct aaggcataac caaggcgcca gcctgtcata gcatatgctt
     8101 tagaaaaacc gtttaaaatg atactgcgtt ctttcatatc aggtaaagca gaaaaacaaa
     8161 tatgtttacg ttcgccataa gtcaaatcgc cataaatttc atcggatatg acaattaaat
     8221 tatgcttttg ggcaaaatta gcaatagcga gtaattcatc atattctaaa attgttcctg
     8281 ttggattgtt aggatagccg attaataatg cttttgtctt tggcgtaata tgtttttcta
     8341 aatcttcagg agttactttg aattcatttt ctgatttagt aggtacagca atagctttgg
     8401 caccaactaa agtagcacaa gctgcataag atacatagca tggctcggga attaaaattt
     8461 catcattagg atttaagata gcacgcatag caaggtcaac agcttcacta acgccaacag
     8521 tgatgagtac ttcatcatta ggattgtatt ttacttgaaa atctctttcg tacatatgtg
     8581 taatggcatg acgtaattca taaagacctt tattgctagt atatgcagta tatccacgtt
     8641 ctaagccata gatacagctt tcgcggatag tccaaggtgt tacaaaatca ggttcaccaa
     8701 taccaagact gatgacatct tccatagtgg aagcaatatc aaaaaaacgg cgaataccgg
     8761 attgttttgt atgttgtaca gtagttgcta aatttttatt ccaatcaatc atggtgatac
     8821 caccaatcta tggtcagttt ctttatcatc aatgataata ccatcttttt tataaggttt
     8881 gagcataaaa tgactgcgtg tagaagtaac gccttcgatt gtagaaagac gacgagcgac
     8941 aaagtcagct acatttttta aagatttacc ttcaatgata actaataaat caaagctacc
     9001 agacattaga taaacagttt ttacttcatc aaaacgataa attctttcgg cgatagcatc
     9061 aaaaccaaat tcacgctgtg gagtaacatt gacttcaatc atagcagaaa cgctatcatc
     9121 tccgtatttt tcccagtcaa tcatagtgtt gtagccaaga ataatttttt ctttttctag
     9181 ctttttcatt tgttcttcta tttcatattc agaacgacca agcatcgtag caagttcttt
     9241 gattgaacga cgtccatcat gttctagtaa ttctaatagt tcacgcataa aatcacttcc
     9301 ttagtaagtt taatgaatag taatttagta atctttattt tagcgaaaaa acaaagaccc
     9361 tcgtccaata aaggacgagg gtcttctccc gtggtaccac cttagttagc aaatagctca
     9421 cttaatgccg atatcgctgg catagcgcct agttttgcta ggtgctcacg ggtagctttc
     9481 taattttatc gcttgatagc tcgcaccaac cgctatttct ctgaaagtca acaaaattat
     9541 acttttccgc tcattgcatt ttatatatgt gtaataatgt taacataaaa ttagaataaa
     9601 aatcaagtgt tagatgaata aatgtaaaat taaatataca atagcagata aaattgcagt
     9661 acatggaatt gtcataagcc aagcgacaag catttgacga gcaacgtccc aatgtacagc
     9721 tttaatacgt tgggcagcac ctacacccat gatagaacca gaaactacat gcgtagtaga
     9781 tactggtaaa tgtagaagtg tagcgccaaa gattactaca gctgagttta aatcagcaga
     9841 aaatccatga acaggttgca tgcggaagat tttcccgcca acagttctga tgattttcca
     9901 accaccaaaa gaagtaccga gagccatagc aaaagcacat gatattttta caaaagtagg
     9961 tacttctaaa gcaccgatat agccaccgct taaaagagca agtgtgataa tccccatgga
    10021 tttttgtgcg tcgttagaac catgagcaaa tgccattaaa gcagcagaaa ttacttggag
    10081 acgattgcaa ttatcattga cagtagctgg tctcatggaa tgacagatag caaaaataat
    10141 atgtagtata atccaaccaa ttgccatagc agcaagagga gaaagtacta aagataaaaa
    10201 tatttttaaa ataccatagc catttaatcc cataaagcca acggagatga ttacagcgcc
    10261 aatgatacca ccaactaaag catgagaaga actacttggc ataccaaacc accatgttat
    10321 taaattccaa ataatggcac cagctaaagc agcgataatg atgacttcat ttaccataga
    10381 agcagattga actatatcgc caccgatggt tttggcaacg cctgtactaa tcatggcacc
    10441 agcaaaattt aaaatagcag acataatgat agctactgct ggagatactg cacgagttga
    10501 tacgcatgta gcgattgcat ttgctgtatc gtggaaacca tttacaaagt cgaaaataag
    10561 agctaaggca ataacaataa aaattaagat agaagcttgc tcaagcatac ttcataacaa
    10621 ctccttttaa tgtgtcagaa atatgttttg tctgatcaag tgtatcttca aggcattgaa
    10681 gaatatcttt ccattttaca agcgtaatag ggtctttttc agttttgaat aatgaagaca
    10741 tttcactgcg atagagtgta tctccttgac tttcataagt taaaatgcga ttagtgcatt
    10801 caagaatttc attatgattt ttacgaatat cttttaataa tgctgtagct tttactaatt
    10861 cttctgtagc ttgaattaaa agtttagaca attttgcagg gccgtctgtt tttggttgac
    10921 ctgcttcata catgataact cgttcaagac taccatgaat attatcaaca ccatcatcta
    10981 aaccataaga aagagcgaaa atatcttcac ggtcaattgg agtgatgaat acttgattta
    11041 acttttgtac agtttctgct gtaactaaat cagcttgttt ttcaacagtt tttatttctt
    11101 ccattttggt ttgagctgta tcgtaattaa tcattacatc atacattatt ttggaacctt
    11161 ggttaaaata tttagcatgt tgattgagca tatcaaaaaa ttcatagtgt ttgtttccga
    11221 tatcaaacat aaaataatcc tcctgaagtt ttttattgga attttcatac tgaaaataag
    11281 tataaaagcc taataagaag aataaatata tttttggtaa aatctaagta aaattgaagg
    11341 atttattatt ttagtgaaaa tttatatatt aatggatatg aaaataaatc tataaacaat
    11401 agcttttctt gttcataata atagacatca taggttttct aatgtacaat agaagtgagt
    11461 ttttttctta atttacagga ggaataaaat tgtcagttag aagattgtat gttgaaaaac
    11521 gccaaggttt tgatattcca gctcagaaac tctttgctga tttaaaagag ttatttgcaa
    11581 ttgaaggaat agaacaagta agagttatcc gtagatatga tattgaagga ttaactgatg
    11641 cagaatatgc acagacaaaa ccagttgtat tttatgaacc accagtagat gtaatttatg
    11701 aagaagaatt accagaaata gcaaatgctc gtgtatttgc agtagaagct cttccaggtc
    11761 aatttgacca gactgctgat tcagctgcac agtgtgtaca gctcgttaca cagaaagaac
    11821 gtccagttat ccgcagtgca aaagtaattg ctttaattgg taatattgat gatgaaattt
    11881 ttgctaaaat aaaaaattac tgcattaatg ctgtagaatc tagagaagct tcttttgaaa
    11941 aacctgaaac acttgcaatg gttatggaag aaccagctga tgtaaaaata cttacaggct
    12001 ttatttctat gaatgatagc caacttattg ctttaagaaa tgaaatgggc ttagcaatga
    12061 gtgaagaaga tttgaaattc tgtcaagaat attttgctaa agaagaaaaa cgtgatccta
    12121 gtattactga aattcgcgtt attgatactt attggtctga ccattgtcgt catactacat
    12181 ttacaacagc tatcgacaat gttgatattg aagaaggtaa atataaagaa acaataaaaa
    12241 atgcttatca gttatattta aatgaccgtg aagcattagg tagaactcat aaagatgtta
    12301 ctttaatgga catcgctgta atgggtatgc gtaaacttcg tgaagaaggc aaattacaag
    12361 acctagacgt atctgaagaa atcaatgctt gtagtattgt cgtaaaagcc aatattgatg
    12421 gaaagcaaga agattggctt gtaatgttta aaaacgaaac tcacaatcat cctactgaaa
    12481 ttgaaccatt tggtggtgcg gcaacttgcc ttggtggtgc tatccgtgat ccactttctg
    12541 gtcgttctta tgtatatcaa gctatgcgtg taacaggtag tgctgatcct cgtcgtagtc
    12601 ttgaagaaac aattaaaggt aaattaccac agcgtaaaat tactcgtggt gcagcacatg
    12661 gttatagttc ttatggtaac cagattggtt tggcaacagg acaggttcat gaaatttatc
    12721 atgaaggtta tgcagcaaaa cgtcttgaaa tcggtgcagt agtagctgca gctccaaaag
    12781 aaaatgtact tcgttttgaa ccacaaccag gtgatgtagt tattttagtc ggcggacgta
    12841 ctggtcgtga tggtatcggc ggtgcaacag gttcttctaa agaacatact ttagaatctt
    12901 tgactcagtg cggtgcagaa gtacaaaaag gtaatcctcc aactgaacgt aaattacaaa
    12961 gattatttag aaatccagaa gttagtcgct taatcaaacg ttgtaatgac tttggtgcag
    13021 gcggtgtagc tgtagctatt ggtgaattaa cagatggtct tgtaattgaa cttgataaag
    13081 ttaagaaaaa atatgatggt cttgatggaa cagaacttgc tatttctgaa tctcaggaac
    13141 gtatggcagt tgttgtagat gctaaagatg cagataaatt catagctgaa tctgcaaaag
    13201 aaaatcttga agcaacactt gtggcaactg taactaaaga acctcgtctt gttatgaatt
    13261 ggcgtggtaa tgatatcgtt agcattaaac gttctttcct tcagacaaac ggtgtaaaac
    13321 agcatactga tgctgtagta aaaatgccag aaggcaaaac atattttgaa caagcaaaac
    13381 aagtagaagg ctctgtaaaa gatgcttggc ttaatacttt aaaagattta aatgtatgca
    13441 gtcagaaagg tttaagtgaa caattcgact ctacaatcgg tgctaataca gtacttatgc
    13501 catttggtgg taaacgtcaa atgacaccag cagaaggtat ggtagctaca ttaccattat
    13561 tagaaggttc tacaaataca gctactgcta tgacatttgg tttcaatcca tatctcatga
    13621 gctggagccc attccatggt gcagtatatt ctatcgtaga agctattaca aaaatcgtag
    13681 ctatcggcgg tgattatgca aaagttcgct taactctcca agaatatttt gaaagccttg
    13741 gtaaagatag cgaaaaatgg ggtaaaccat ttgctgcact tttaggtgca ttatgggcac
    13801 agcataaatt cggtacagct gctattggcg gtaaagactc catgtctggt acattcatgg
    13861 atatgacagt accaccttct ttaatcgctt ttgctcttga tatggtagaa gcagataaag
    13921 ttgtatctcc tgaatttaaa caagcaggac ataaagttat catagttaaa gcaactcgtg
    13981 atgaattcga aatgccagtt attgatacat tgactgctaa cttcaataaa gtttatgaat
    14041 taattcatgc aggtaaagtt gcaagtgcaa aaactgtagg cgttggcggt attgctagtg
    14101 caatcagcaa aatgacactt ggtgaacaac tcggttttgc ttttgctgat ggctttgata
    14161 caaaagaatt attcgcttgc gattatggta caatcattct tgaattaaat gaagatgtag
    14221 atttaaatga atttgtaggt gcatatgaac ttggtagtgt aattgctgac aaagcaatta
    14281 tctgtggcga tgtaaaaatt tcccttgatg aaattgaaac agcatacact cagccacttg
    14341 aacagatttt cccaactcat gtacgtaaat ctactggtga aacaaaacaa agtgaacttt
    14401 atacagcaac tagcattgct aaagctccaa cttcttttgc taaaccaaga attttcattc
    14461 cagtattccc aggtacaaac tgtgaatatg atactgctaa agcatttaat cgtgcaggtg
    14521 gtcaagctga aactctcgtt attaaaaact tgactccttc catggttgaa gaatccgttg
    14581 aagctattgt aaaaggcatt gaaaaatctc agattatcat gcttccaggt ggtttcagtg
    14641 gtggggacga accagatggt tctggtaaat tcattgctgc tatgtttaga aatccacgta
    14701 ttacagaagc tgttcgcgat ttactcaaaa accgtgatgg tttaatgctc ggtatctgca
    14761 atggtttcca agctctcatc aaattaggtc ttgtaccatt tggtgatatt caagaattaa
    14821 caccagaaaa tccaacactc acatacaatg aaattggtcg tcacgtatct tgcatggtag
    14881 aaacaaaagt tgtatctaat ctctctccat ggtttaataa cgtaaaagta ggagatattc
    14941 atactattgc tgtttctcat ggtgaaggtc gcttctgtgc aagtccagaa gttttagctc
    15001 aattaaaagc taatggtcag attgcaactc aatatgtaaa tgcaaatggc gatacttcta
    15061 tggatattga agtaaatcca aatggttctg tatgggctat cgaaggtatc acaagtccag
    15121 atggacgtat cttaggtaaa atgggacact ccgaacgtat tggcaaatat gtagctaaaa
    15181 atgttccagg tgcaaaagac caaaaattat ttgaagctgg cgtagctt
//
