LOCUS       NZ_CP021520.1          22592 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP021520.1 Neisseria meningitidis strain 11-7 chromosome,
            complete genome.
ACCESSION   NZ_CP021520
VERSION     NZ_CP021520.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:49:13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 561840
            Orig. end    :: 584432
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22592
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[571840:574432]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12592
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..22592
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22592
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="2"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(168..749)
                     /locus_tag="ctg1_526"
                     /transl_table=11
                     /translation="MNLRDDLQLIYDRIPEGSRVLDLGCGDGELLAALVEHKKCSGYGI
                     EIDTDSVIAAMSRGVNVIQADLEEGLTAFNDQSFDVIVLSQTIQAMQNTEKILRCLMRV
                     AKQAIVSFPNFGYWRNRVQIALGGHMPVSERMPYHWYDTPNIHWCTLKDFDLLCAKNNI
                     RVLERAVMTSNRQVKHFPNLLGSLAFYRVG"
     CDS             complement(746..1885)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_527"
                     /sec_met_domain="Abhydrolase_1 (E-value: 4.8e-35, bitscore:
                     118.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQNASVGIVMPQKIPFEMPLVLENGKTLPRFDLMIETYGELNAE
                     KNNAVLICHALSGNHHVAGRHSAEDKYTGWWDNMVGPGKPIDTERFFVVGLNNLGGCDG
                     SSGPLSINPETGREYGADFPLVTVKDWVKSQAALADYLGIGQWAAVVGGSLGGMQALQW
                     AISYPERVRHALVIASAPKLSTQNIAFNDVARQAILTDPDFNEGHYRSRNTVPARGLRI
                     ARMMGHITYLAEDGLGKKFGRDLRSNGYQYGYGVEFEVESYLRYQGDKFVGRFDANTYL
                     LMTKALDYFDPAADFGNSLTRAVQDVQAKFFVASFSTDWRFAPERSHELVKALIAAQKS
                     VQYIEVKSAHGHDAFLMEDEAYMRAVAAYMNNVYKECQQ"
     CDS             2035..2235
                     /locus_tag="ctg1_528"
                     /transl_table=11
                     /translation="MIGRLFRIFFFFALAALIINRLFSRRQKRALREVAEISAWVLLGA
                     AAAMLFWYLFMLYFKHIPDSY"
     CDS             complement(2447..2572)
                     /locus_tag="ctg1_529"
                     /transl_table=11
                     /translation="MQVLSSLKTAKQRHRDCQIVRRRGKVYVICKSNPRFKARQR"
     CDS             complement(2572..2847)
                     /locus_tag="ctg1_530"
                     /transl_table=11
                     /translation="MKPNIHPDNYRTVLFFDSSANEGWLIRSCAETHGKTMVWTDGKEY
                     PLFSLDTSSASHPVYTGKQRNVNTEGRASKFNQRFQSVMSSFRKDK"
     CDS             3047..3925
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MTHFR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_531"
                     /sec_met_domain="MTHFR (E-value: 5.9e-109, bitscore: 360.7,
                     seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHR
                     LQTLHPKFVSVTYGANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDY
                     WDSGIRRIVALRGDEPAGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQAD
                     LINLKRKIDAGANHVITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMA
                     QVTNVKIPSWLSQMYEGLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELT
                     YAICHILGVRP"
     CDS             4063..6339
                     /locus_tag="ctg1_532"
                     /transl_table=11
                     /translation="MTTLHFSGFPRVGAFRELKFAQEKYWRKEISEQELLAVAKDLREK
                     NWKHQVAANADFVAVGDFTFYDHILDLQVATGAIPARFGFDSQNLSLEQFFQLARGNKD
                     QFAIEMTKWFDTNYHYLVPEFHADTGFKANAKHYVQQLQEAQALGLKAKPTVVGPLTFL
                     WVGKEKGAVEFDRLSLLPKLLPVYVEILTALVEAGAEWIQIDEPALAVDLPKEWVEAYK
                     DVYATLSKVNAKILLSTYFGSVAEHAALLKALPVDGLHIDLVRAPEQLDAFADYDKVLS
                     AGVIDGRNIWRANLNKVLETVEPLQAKLGDRLWISSSCSLLHTPFDLSVEEKLKANKPD
                     LYSWLAFTLQKNQELRVLKAALNEGRDSVAEELAASQAAADSRANSSEIHRADVAKRLA
                     DLPANADQRKSPFADRIKAQQAWLNLPLLPTTNIGSFPQTTEIRQARSAFKKGELSAAD
                     YEAAMKKEIALVVEEQEKLDLDVLVHGEAERNDMVEYFGELLSGFAFTQYGWVQSYGSR
                     CVKPPIIFGDVSRPEAMTVAWSTYAQSLTKRPMKGMLTGPVTILQWSFVRNDIPRATVC
                     KQIALALNDEVLDLEKAGIKVIQIDEPAIREGLPLKRADWDAYLNWAGESFRLSSAGCE
                     DSTQIHTHMCYSEFNDILPAIAAMDADVITIETSRSDMELLTAFGEFKYPNDIGPGVYD
                     IHSPRVPTEAEVEHLLRKAIEVVPVERLWVNPDCGLKTRGWKETLEQLQVMMNVTRKLR
                     AELAK"
     CDS             6618..7355
                     /locus_tag="ctg1_533"
                     /transl_table=11
                     /translation="MALQDRTGQKVPSVVFRTRVGDTWKDVSTDDLFKGKKVVVFSLPG
                     AFTPTCSSSHLPRYNELFGAFKENGVDAIYCVSVNDTFVMNAWAAEEESDNIYMIPDGN
                     GEFTEGMGMLVGKEDLGFGKRSWRYSMLVNDGVVEKMFIEPEEPGDPFKVSDADTMLQF
                     VAPDWKAQESVAIFTKPGCQFCAKAKQALQDKGLSYEEIVLGKDATVTSVRAITGKMTA
                     PQVFIGGKYIGGSEDLEAYLAKN"
     CDS             7538..9007
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_534"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.5e-42, bitscore:
                     142.8, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 5.6e-20, bitscore:
                     68.6, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSETDMFCVGNVSDENGRTKIMKKIQADVVVLGGGTAGMGAFRN
                     ARLHSDNVYLIENNVFGTTCARVGCMPSKLLIAAAEARHHALHTDSFGVHLDKDSIVVN
                     GEEVMQRVKSERDRFVGFVVADVEEWPADKRIMGSAKFIDEHTVQIDEHTQITAKSFVI
                     ATGSRPVILPQWQSLGNRLIINDDVFSWDTLPKRVAVFGPGVIGLELGQALHRLGVKVE
                     IFGLGGIIGGISDPVVSDEAKAVFGEELKLHLDAKTEVKLDADGNVEVHWEQDGEKGVF
                     VAEYMLAAVGRRPNVDNIGLENINIEKDARGVPVADPLTMQTSIPHIFIAGDASNQLPL
                     LHEAADQGKIAGDNASRYPNIGGGLRRSTIGVVFTSPQIGFVGLKYAQVAAQYQADEFV
                     IGEVSFKNQGRSRVMLVNKGHMRLYAEKATGRFIGAEIVGPAAEHLAHLLAWAHQMKMT
                     VPQMLDMPFYHPVIEEGLRTALRDADAKLKA"
     CDS             9286..9663
                     /locus_tag="ctg1_535"
                     /transl_table=11
                     /translation="MSAKPRPVYLDLPNIRLPIPGIVSILHRISGVGLFIMLPFLLYFL
                     SGTLSQESAFETYRAIVSHPLVKLVLIGVLWAYLHHSLAGIRFLFLDAHKGLELNTARN
                     TAKAVFASALVLTVVLGALLW"
     CDS             9657..9998
                     /locus_tag="ctg1_536"
                     /transl_table=11
                     /translation="MVERKLTGAHYGLRDWAMQRATAVIMLIYTVALLVVLFSLPKEYS
                     AWQAFFSQTWVKVFTQVSFIAVFLHAWVGIRDLWMDYIKPFGVRLFLQVATIVWLVGCL
                     VYSIKVIWG"
     CDS             10001..11764
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 407.1; E-value:
                     3.2e-124)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_537"
                     /sec_met_domain="FAD_binding_2 (E-value: 1e-122, bitscore:
                     407.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 6.1e-41,
                     bitscore: 136.3, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFPVRKFDAVIVGGGGAGLRAALQLSKSGLNCAVLSKVFPTRSH
                     TVAAQGGISASLGNVQEDRWDWHMYDTVKGSDWLGDQDAIEFMCRAAPEAVIELEHMGM
                     PFDRVESGKIYQRPFGGHTAEHGKRAVERACAVADRTGHAMLHTLYQQNVRANTQFFVE
                     WTAQDLIRDENGDVVGVTAMEMETGEVYIFHAKAVMFATGGGGRIYASSTNAYMNTGDG
                     LGICARAGIPLEDMEFWQFHPTGVAGAGVLITEGVRGEGGILLNADGERFMERYAPTVK
                     DLASRDVVSRAMAMEIYEGRGCGKNKDHVLLKIDHIGAEKIMEKLPGIREISIQFAGID
                     PIKDPIPVVPTTHYMMGGIPTNYHGEVVVPQGDEYEVPVKGLYAAGECACASVHGANRL
                     GTNSLLDLVVFGKAAGDSMIKFIKEQSDWKPLPADAGELTRQRIERLDNQTDGENVDAL
                     RRELQRSVQLHAGVFRTDEILSKGVREVMAIAERVKRTEIKDKSKVWNTARIEALELDN
                     LIEVAKATLVSAEARKESRGAHASDDHPERDDENWMKHTLYHSDTNTLSYKPVHTKPLS
                     VEYIKPAKRVY"
     CDS             11885..12592
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 108.1; E-value: 7.4e-34)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_538"
                     /sec_met_domain="Fer2_3 (E-value: 2.4e-32, bitscore: 108.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.4e-10, bitscore: 38.5,
                     seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKMSFEIYRYNPDVDAKPYMQRYELELEPTDVKLLDALVRLKAQ
                     DDTLSFRRSCREGICGSDGMNINGKNGLACLTDLRGLKQPVKIRPLPGLPVIRDLIVDM
                     TQFFKQYHSVKPYVVNDNPIDADKERLQTQEERKELDGLYECILCACCSTACPSFWWNP
                     DKFVGPSGLLNAYRFIADSRDTITNERLDNLNDPYRLFRCHTIMNCVDVCPKHLNPTRA
                     IGKIKEIMLKRAV"
     CDS             12596..12844
                     /locus_tag="ctg1_539"
                     /transl_table=11
                     /translation="MMVFDDIAKRKIRFQTRRGLLELDLIFGRFMEKEFEHLSDKELSE
                     FSEILEFQDQELLALINGHSETDKGHLIPMLEKIRRA"
     CDS             12956..14239
                     /locus_tag="ctg1_540"
                     /transl_table=11
                     /translation="MSKSIKLNVPGQAGLELPVLEASIGHDVVDIRGLTKNTGLFSFDP
                     GFVSTASCESKITYIDGDQGLLYYRGYPIEQLAEKSDYLEVCYLLIYGELPTPEQKAEF
                     DNTVRRHTMVHEQLTWFFRGFRRDAHPMAMMVGVVGALSAFYQDSLDISNPEHRKIAIY
                     RLISKIPTIAAMCYRYSNGLPFNYPKNNLSYSENFLHMMFATPCEDYKPNPVLARALDR
                     IFILHADHEQNASTSTVRLAGSSGANPFACIAAGIACLWGASHGGANEAVLKMLDEIGD
                     VSNVAAYMEGVKQRKYRLMGFGHRVYRNMDPRASIMRETCYEVLKELGLEDSPKFKLAM
                     ELEQIALKDPFFIERKLYPNVDFYSGIVLSALGIPTEMFTVIFALSRSVGWISHWHEMI
                     SDPSLKIGRPRQLYTGSERRDYVPPGER"
     CDS             14444..17272
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) E1_dh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_541"
                     /sec_met_domain="E1_dh (E-value: 4.8e-50, bitscore: 167.1,
                     seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 1.1e-63, bitscore:
                     211.1, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMDEKLNFSYLFGSNAPYIEELYEAFLENPDTVDEKWKQYFTDLS
                     KQPGTVAVDVAHTPIRESFVTLAKKKIASAVAGGADEAMLKKQVSVLRLISAYRIQGVG
                     AAQLDPLKRIPPRDIEALDPKFHGLSDADMALQFNMGEGDFANRGKLPLSQIISNLKQT
                     YCGHIALEYIYIPNTEERRWVRNYFESVLSTPHYNADQKRRILKEMTAAETLERYLHTK
                     YVGQKRFGVEGGESAIAGLNYLIQNAGKDGVEEVIIGMAHRGRLNVLVNILGKKPGDLF
                     AEFEGRAEIKLPSGDVKYHMGFSSDIATPHGPMHVSLAFNPSHLEIVNPVVEGSARAKQ
                     KRLGENGRDKVLPVLIHGDSAFIGLGVNQATFNLSKTRGYTTGGTVHIVINNQIGFTTS
                     DIRDTRSTVHCTDIAKMVSAPVIHVNGDDPERVCFAIQAALDYRKKFHKDIVIDVVCYR
                     KWGHNEGDDPTLTQPMMYKKVSQHPGARALYTEQLIAEGVVTQAEADGYIQAYRDALDK
                     GEHVEQTTLSNFQRTQIDWSKYQGKDWREHIETGLPAADIERLTEKFTAVPEGFALHPT
                     AKRVIEARKAMASGKQAIDWGMAETLAYASLVTKGHGVRISGEDSGRGTFSHRHAVLHD
                     QKREKWDDGTYVPLRHMGEGMGEFLVIDSILNEEAVMAFEYGFACSAPDKLTIWEAQFG
                     DFANGAQVTIDQFLSSGETKWGRLCGLTTILPHGYDGQGPEHSSARVERWLQLCSENNM
                     QVIMPSEASQMFHLLQRQVLGSYRKPLVIFMSKRLLRFKGAMSPLENFTEGSTFRPVVG
                     DTAERASNDSVKRVVLCAGQVYYDLEAGRAERKLEDDVAIVRVEQLYPFPYDEVKAELA
                     KYPNAKSVVWAQEEPKNQGAFYQIRHRIEDVISEEQKLSYAGRPSSASPAVGYSSKHIA
                     QLKQLVEDALAL"
     CDS             17372..18553
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) oxoacid_dh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 75.3; E-value:
                     8.6e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_542"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.7e-22, bitscore:
                     75.3, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="oxoacid_dh (E-value: 6.2e-83, bitscore:
                     274.7, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIDVKVPMLSESVSEGTLLEWKKKVGEAVARDEILIDIETDKVV
                     LEVPSPQAGVLVEIVAQDGETVVADQVLARIDTAATAAAEAPAAAPAEAAPAAAPAAAQ
                     NNAAMPAAAKLAAESGVDVNALQGSGRDGRVLKEDVQNAAAKPAAAAAPAVALPAGARP
                     EERVPMSRLRARVAERLLASQQENAILTTFNEVNMKPIMDLRAKYKEKFEKEHGVKLGF
                     MSFFVKAAVAALKKYPVVNASVDGKDIVYHGYFDIGIAIGSPRGLVVPILRDADQMSIA
                     DIEQAIVDYAKKAKDGKIAIEDLTGGTFSITNGGTFGSMMSTPIINPPQSAILGMHATK
                     ERAVVENGQVVVRPMMYLALSYDHRIIDGREAVLTLVAIKDALEDPARLLLDL"
     CDS             18918..20351
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_543"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.8e-69, bitscore:
                     230.5, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 1.6e-35, bitscore:
                     118.6, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQYDVVVIGAGPGGYVAAIRAAQLGFKTACVDAGVNKAGNAPAL
                     GGTCLNVGCIPSKALLQSSEHFHAAQHEFAEHGITVGDVKFDVAKMIERKDAIVTKLTG
                     GVKFLFQKNKVTSLFGTASFAGKNGDAYQIEVDNKGEKTVIEAKHVIVATGSVPRPLPQ
                     VAIDNVNVLDNEGALNLTEVPAKLGVIGSGVIGLEMGSVWNRVGAEVTILEAAPTFLAA
                     ADQQIAKEAFKYFTKEQGLSIELGVKIGDIKSEGKGVSVAYETAAGEAKTEVFDKLIVA
                     IGRIPNTKGLNAEAVGLEKDERGFIKVDGECRTNLPNVWAIGDVVRGPMLAHKASDEGV
                     AVAERIAGQKPHIDFNNVPFVIYTDPEIAWVGKTEEQLKAEGVEYKKGTSGFGANGRAL
                     AMGKAKGTVKVLADAKTDRILGVHMIGPVVSELLTEGVTALEFFASSEDIARIIHAHPT
                     LSEVVHEAALAADKRALHG"
     CDS             20446..20733
                     /locus_tag="ctg1_544"
                     /transl_table=11
                     /translation="MNKEIVGIFFIPMGIISMCMAALWQMYVMMTETYTLNRFKDKELV
                     WRVALLFISFSLAVYLLCPNSRKKGIVFFILGGGGAAMYLLARMWLPFSK"
     CDS             20832..21998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GARS_A"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ligase_CoA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_545"
                     /sec_met_domain="GARS_A (E-value: 4.3e-05, bitscore: 20.3,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Ligase_CoA (E-value: 3.3e-26, bitscore:
                     88.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLHEYQAKELLAGYGLPVQGGILAHNGEEAAAAYDKLGGKFAVV
                     KAQVHAGGRGKAGGVKVVKSREEAKEVAESLIGTNLVTYQTDANGQPVNSVLVCEDMYP
                     VQTELYLGAVVDRSTRRVTFMASTEGGVEIEKVAAETPEKIFKVTVDPLVGLQPCQARE
                     VAFQLGLKDKQINEFVKLMTGAYKAFVENDFALFEVNPLAVRENGALACVDGKIGIDSN
                     ALYRLPKIAELRDKSQENERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLKG
                     GQPANFLDVGGGATKDRVVEAFKLILEDKSVQGVLINIFGGIVRCDMIAEAIVAAVKEI
                     NVDVPVVVRLEGNNAELGAKILNESGLKLTSADGLNDAAEKIVAAVNA"
ORIGIN
        1 cagcatgatt gcggtaagcc ataagagaag tgatgaggtt ttgtttttca ttctattgtt
       61 tccagtatta aagaggccgt ctgaaaacct accgtttcat ttttcagacg gcctgttgtt
      121 aatagaaccg aagaacctgt tattgccgac aaggttctca acctgtctta cccgacgcgg
      181 taaaacgcca ggctgcccaa aaggttgggg aaatgtttga cctgtctgtt gctcgtcatc
      241 acggcgcgtt cgaggacgcg gatgttgttt ttggcgcaca acaaatcaaa atctttgagc
      301 gtgcaccaat ggatattggg cgtgtcgtac caatggtagg gcatacgttc ggaaaccggc
      361 atatgtccgc cgagtgcgat ttggacgcgg ttgcgccagt agccgaaatt cgggaagctg
      421 acaatcgcct gtttggcaac gcgcatcagg cagcgcagga ttttttcggt attctgcatc
      481 gcttggatgg tttggctcaa cacaatcaca tcaaaacttt gatcgttgaa tgcggttaaa
      541 ccttcttcca aatcggcttg gataacattt acgccgcgcg acatcgcggc gatgacgctg
      601 tcggtgtcga tttcgatgcc gtagccgctg cattttttgt gttcgaccaa tgcggcaagc
      661 agttcgccgt cgccgcagcc caagtccaag acgcggctgc cttcgggtat ccggtcgtaa
      721 atcagttgca aatcatcgcg caggttcatt gctgacattc cttataaacg ttgttcatat
      781 aggcggcgac cgcacgcata taggcttcgt cttccattaa aaaggcatcg tgcccgtgtg
      841 cggatttgac ttcgatatac tgcacggatt tttgggcggc aatcagggcc ttgaccagtt
      901 cgtgcgaacg ttcgggcgcg aaacgccaat cggtgctgaa gctggcgaca aagaattttg
      961 cctgaacatc ctgcacggcg cgggtcaggc tgttgccgaa atccgccgcc ggatcgaaat
     1021 agtccaaagc cttggtcatc agcaaatagg tgttggcatc aaaccgcccg acgaatttgt
     1081 cgccttgata gcgcagatag gattctactt caaattcaac gccatagccg tattgatagc
     1141 cgttggaacg caaatcgcgt ccgaattttt tgcccaaacc gtcttcggca agataggtga
     1201 tgtgccccat catgcgggca atccgcaagc cccgagcggg aacggtgttg cggctgcggt
     1261 aatgtccttc gttgaaatcg ggatcggtca aaatcgcctg acgcgccaca tcgttgaacg
     1321 cgatattttg cgtggacagt ttcggcgcgg acgcaatcac caaggcgtgg cgcacgcgtt
     1381 cgggatagga aatcgcccac tgcaaagcct gcatgccgcc caagctgccg ccgacaaccg
     1441 ccgcccattg cccgatgccg agataatcgg caagcgcggc ttgggatttt acccagtcct
     1501 tcaccgtaac cagcggaaaa tccgcgccgt attccctgcc cgtttcagga ttaatcgaca
     1561 aaggcccgct gctgccgtcg cagccgccca gattattcaa accgaccacg aaaaaacgtt
     1621 ccgtatcaat cggtttgcca ggtccgacca tattgtccca ccagcccgta tatttatctt
     1681 ccgccgaatg cctgcccgca acatgatggt tgcccgacag cgcgtggcag attaaaaccg
     1741 cattgttttt ttcagcattc agctcgccgt aggtttcaat catcagatcg aaacgcggca
     1801 aagttttacc gttttccaaa accagcggca tctcaaacgg aattttttgg ggcattacaa
     1861 tgcccaccga ggcattttga ctcatatcct gttccaacaa atgcggcgaa aagcgttatt
     1921 atatcgcaaa cggcatgact ttttgacacg gtcggacaag cagccggacg cgtttgaccc
     1981 tcatccgccg cacacgaatc atactttttc agacgacctc caccgcttcc cgacatgata
     2041 ggcagacttt tccgtatttt tttctttttc gcacttgccg cgttgattat caaccgcctt
     2101 ttcagccgca ggcaaaaacg cgccctgcgc gaagtcgccg aaatcagcgc atgggtactg
     2161 ctcggtgcag ccgccgcgat gctgttttgg tatctgttta tgctgtattt caaacacatt
     2221 ccggattcgt attgacggaa aaaatgccgt ctgaaacgca tttttctgtt tcagacggca
     2281 tatttgatga aaagggcttg cggtaggagg tgctttatag tggattaaat ttaaaccagt
     2341 acggcgttgc ctcgccttgc cgtactattt gtactgtctg cggcttcgtc gccttgtcct
     2401 gatttttgtt aatccactat acaaccgaag caggaagggc agggagtcag cgttggcgcg
     2461 ctttaaaacg cggattgctt ttgcagatga cgtaaacttt gcccctgcgt ctgacgattt
     2521 ggcagtcgcg gtggcgttgt ttggcggttt tgagtgaaga cagaacctgc attatttgtc
     2581 ctttctaaac gatgacatga cggattggaa acgttggttg aacttgctgg cgcgtccttc
     2641 ggtgttgacg ttacgctgct tgccggtata gacgggatgg gatgcggaag aagtatccag
     2701 cgaaaacagc ggatattctt tgccgtctgt ccaaaccatc gtttttccgt gtgtttcggc
     2761 acaggagcgg attaaccagc cttcattggc gctgctgtcg aaaaaaagga cggttcgata
     2821 attgtcagga tgaatatttg gtttcatata ttgccttgct ttcagtgtta taacataaca
     2881 aactctagca tagtttagaa gggctgtaca aggaaattta actatttttg taatatatta
     2941 gaaattttca tgataaatct gaaaattttg aaattgactc atgtttggcg caactttatt
     3001 atgttgcctg aaacatcata taaaagataa taaaaggtac gcagccatga attacgcaaa
     3061 agaaatcaat gcgttaaata acagtctttc tgatttgaaa ggcgacatta acgtttcgtt
     3121 tgaatttttc ccgccgaaaa acgaacaaat ggaaacgatg ctgtgggact ccatccaccg
     3181 tctgcaaacc ctgcatccca agttcgtatc cgtaacttac ggcgcaaatt ccggcgaacg
     3241 cgaccgcacg cacggcatcg tcaaacgcat caaacaggaa accggcttgg aagccgcgcc
     3301 tcacctgacc ggtatcgacg cttctcccga cgaattgcgc caaattgcca aagattattg
     3361 ggacagcggc atccgccgca ttgtcgccct gcgcggagac gagccggccg gttatgagaa
     3421 aaaaccgttt tacgccgaag acttggttaa gctattacgc tccgtcgccg acttcgacat
     3481 ctctgtagca gcatatcccg aagtgcatcc cgaagcgaaa tccgcacaag ccgacctgat
     3541 taatttgaaa cgcaaaatcg atgcgggcgc gaaccacgtc atcacccaat tcttcttcga
     3601 tgtggaacgc tacctgcgct tccgcgaccg ctgcgtgatg ttgggtatcg atgtggaaat
     3661 cgtccccggt attttgcctg ttaccaactt caagcagctc ggtaaaatgg ctcaagtaac
     3721 caacgtcaaa atcccaagct ggctgtcgca aatgtatgaa ggtttggacg acgaccaagg
     3781 tacgcgcaat ctggtggcgg caagtatcgc catcgatatg gtcaaagtcc tgtcccgcga
     3841 aggcgtgaaa gatttccact tctatacgct taaccgcagc gagctgactt acgccatttg
     3901 ccatatttta ggcgtgcgcc cttaaagccg tatcaaacag tttcagacgg catctaaggt
     3961 gtctaaaaag caaaacaccg ccccatccga gccattctga tttacaatac cggccgattc
     4021 ggattgaacc ggtccttaca aaatccaact ggagagttca acatgacaac attacatttc
     4081 tcaggcttcc cgcgtgtcgg cgccttccgc gaattgaaat tcgcacaaga aaaatactgg
     4141 cgcaaagaaa tcagcgagca agaattgctg gctgttgcta aagacttgcg cgagaaaaac
     4201 tggaaacacc aggtcgctgc caacgccgat ttcgttgccg taggcgattt cactttctac
     4261 gaccacatcc tcgacctgca agtcgccacc ggcgcgattc ccgcccgctt cggcttcgac
     4321 agccaaaacc tgtctttgga acaattcttc caactggcgc gcggtaacaa agaccaattc
     4381 gctatcgaaa tgaccaaatg gttcgacacc aactaccact acttggtgcc tgaattccac
     4441 gccgataccg gattcaaagc caatgccaaa cactatgttc aacaactgca agaagcccaa
     4501 gccctcggtc tgaaagccaa accgaccgtt gtaggtccgt tgactttcct gtgggtgggt
     4561 aaagaaaaag gcgccgtcga attcgaccgt ctgagcctgt tgcctaaact gttgcctgtt
     4621 tacgttgaaa tcctgactgc tttggttgaa gccggtgccg agtggattca aatcgacgag
     4681 cctgctttgg ctgtcgattt gcctaaagaa tgggtggaag cctacaaaga cgtttacgct
     4741 actttgagca aagtcaacgc caaaatcctg ttgagcactt acttcggttc tgttgccgaa
     4801 cacgccgcat tgttgaaagc cctgcctgtt gacggtctgc acatcgactt ggtacgcgcc
     4861 cccgagcaac tggacgcgtt cgccgactac gacaaagtcc tgtctgccgg cgtgattgac
     4921 ggccgcaaca tttggcgcgc caacctgaac aaagttttgg aaactgtcga gcctctgcaa
     4981 gccaaactgg gtgaccgttt gtggatttcc agctcttgct cgctgctgca cactccattt
     5041 gacttgtcag ttgaagaaaa actgaaagcc aacaaacccg acctgtactc ttggttggca
     5101 ttcaccctgc aaaaaaacca agaattgcgc gttctgaaag ctgcattgaa cgaaggccgt
     5161 gattctgttg ccgaagaact cgccgccagc caagctgctg ccgactcccg tgccaacagc
     5221 agcgaaatcc atcgtgcaga cgttgccaaa cgcctggccg atttgcctgc caacgcagac
     5281 caacgcaaat ctccatttgc cgaccgtatc aaagcgcaac aagcatggtt gaacctacct
     5341 ctgctgccga cgaccaacat cggttctttc ccgcaaacca ccgaaatccg ccaggcacgc
     5401 tcagccttca aaaaaggcga actgtctgcc gccgattacg aagccgcgat gaaaaaagaa
     5461 atcgccttgg tggttgaaga gcaagaaaaa ctggacttgg acgtactggt acacggcgaa
     5521 gccgagcgta acgacatggt tgaatacttc ggcgaattgt tgagcggttt tgcattcact
     5581 caatacggct gggtacaaag ctacggctca cgctgcgtga aaccaccgat tatctttggc
     5641 gacgtaagcc gtcctgaagc catgaccgtg gcttggtcta cttacgctca aagcctgacc
     5701 aaacgcccga tgaaaggtat gttgaccggc cctgtaacca ttctgcaatg gtctttcgtc
     5761 cgcaacgata ttccccgcgc taccgtgtgc aaacaaatcg cactggctct gaacgacgaa
     5821 gtattggatc tggaaaaagc aggcatcaaa gtcatccaaa tcgacgaacc tgccatccgc
     5881 gaaggtctgc ctttgaaacg tgccgattgg gatgcctacc tgaactgggc gggcgaatct
     5941 ttccgcctgt cctctgccgg ttgtgaagac agcactcaga tccacaccca tatgtgttac
     6001 tccgagttca acgacatctt gccggccatc gccgctatgg atgctgacgt catcaccatc
     6061 gaaacttcac gttccgatat ggaactcttg accgcgttcg gcgaattcaa atacccgaac
     6121 gacatcggcc cgggggttta cgacatccac agcccgcgcg taccgactga agccgaagtt
     6181 gagcacctgt tgcgcaaagc catcgaggtt gtaccggttg agcgtctgtg ggtgaatcct
     6241 gactgcggcc tgaaaacacg tggctggaaa gaaactctgg aacaactcca agtgatgatg
     6301 aacgtaaccc gaaaactgcg tgccgaattg gcgaaataag ccgagaccgt atgaataaat
     6361 accgtctgaa agcctttcag acggtatttt gtcctgattt gcggcgcaag ggcgcagttg
     6421 ccggaaaatc ttttcattgc agcttgtttt tttctcattc ggctttatat gtgggaaaca
     6481 ggcaaatcgg agttgtgttt gatagtttta aataatttat attatttgaa ctataaatta
     6541 tacaaatcat tttgcatggg gtagaatgcc cagcgattca caattatttc tcaaaccaat
     6601 ctattaagga gcttaaaatg gctttgcaag atcgtaccgg tcaaaaagta ccttccgtag
     6661 tattccgcac ccgcgtcggc gacacttgga aagatgtgtc taccgatgat ttgttcaaag
     6721 gcaaaaaagt agtcgtattc tccctgcccg gtgcatttac cccgacttgt tcttcttcac
     6781 acctgccgcg ttacaacgaa ttgttcggcg cgttcaaaga aaacggcgtt gacgcaatct
     6841 actgcgtatc tgtaaacgat acgttcgtaa tgaacgcttg ggctgccgaa gaagaatccg
     6901 acaacatcta catgattcct gatggcaacg gcgaatttac cgaaggtatg ggtatgctgg
     6961 tcggtaaaga agacttgggc ttcggtaaac gctcttggcg ttactccatg ctggttaacg
     7021 acggcgtggt tgaaaaaatg ttcatcgaac ctgaagaacc gggcgatccg ttcaaagtat
     7081 ccgatgcaga tactatgctg caattcgttg ctcccgattg gaaggctcaa gagtctgtgg
     7141 caattttcac taaaccaggt tgccaattct gcgctaaagc caaacaagct ttgcaagaca
     7201 aaggtttgtc ttacgaagaa atcgtattgg gcaaagatgc aaccgttact tccgttcgcg
     7261 ccattaccgg caagatgact gcccctcaag tcttcatcgg cggcaaatac atcggcggca
     7321 gcgaagattt ggaagcttac ttggctaaaa actgatagct gtttgcttaa ggcggtttga
     7381 ttaaactgtc tgatataccg gatagagtta ttcgggcggt tctgcactgc tgctccgaat
     7441 aactctatat ttataagaga atttggatat tgttgcactc aatcgaaatt ttgtttttat
     7501 ttatctgaat gatgtttttg attgggaaaa tatttaaatg ccgtctgaaa ccgatatgtt
     7561 ctgtgtcggc aatgtttcag acgaaaacgg aaggacaaag attatgaaaa aaattcaagc
     7621 ggatgtcgtc gtactcggcg gcggtactgc cggtatgggt gcgtttcgca atgcccgttt
     7681 acattcggat aatgtttacc tgattgaaaa caatgtgttc ggcacaacct gcgcgcgcgt
     7741 gggttgtatg ccttccaaac tcttgattgc cgccgcagaa gcgcgccacc acgcattgca
     7801 taccgactcg ttcggcgtgc atttggacaa agacagcatc gtcgtcaacg gtgaagaggt
     7861 catgcagcgc gttaaatccg agcgtgaccg ttttgtcggc tttgtcgttg ccgatgtgga
     7921 agagtggcct gccgacaagc gcatcatggg ttcggctaaa tttatcgacg agcataccgt
     7981 ccaaatcgac gagcatactc aaattacggc aaaaagtttc gtgattgcta ccggttcgcg
     8041 tcccgtcatc ctgccgcaat ggcagtcttt gggcaatcgt ttgattatca acgatgacgt
     8101 tttctcatgg gatacgctgc ctaagcgcgt tgccgtgttc gggccgggtg ttatcggttt
     8161 ggaactgggt caggcattgc accgtttggg cgtgaaagtt gaaattttcg gtttgggcgg
     8221 aatcatcggc ggcatttccg accccgtcgt ttcagacgag gcgaaagccg tgttcggcga
     8281 agaattgaaa ctgcatttgg atgctaaaac cgaggtcaag ctcgatgcag acggcaatgt
     8341 agaagtccat tgggagcagg atggcgaaaa aggcgtattt gttgccgaat atatgctggc
     8401 agccgtgggc cgccgtccga acgttgacaa tatcggtttg gaaaatatca atatcgaaaa
     8461 agatgcgcgc ggcgtacctg ttgctgatcc gctgaccatg cagaccagta ttccgcatat
     8521 cttcatcgca ggcgatgcgt ccaaccaact gcctctgctg catgaagctg ccgaccaagg
     8581 caagattgcc ggcgataacg cgagccgcta cccgaatatc ggcggcggtt tgcgccgcag
     8641 caccatcggc gtggtgttta ccagtccgca aatcggcttt gtcggtctga aatacgcgca
     8701 ggttgccgcg caataccaag ccgacgaatt tgtcatcggc gaagtatcgt tcaaaaacca
     8761 aggccgcagc cgcgtgatgc tggtaaacaa aggccatatg cgcctgtatg ccgaaaaagc
     8821 caccggccgc tttatcggcg cggaaatcgt aggccctgcc gccgaacatt tggcgcactt
     8881 gttggcatgg gcgcatcaaa tgaagatgac cgttccgcaa atgctggata tgccgttcta
     8941 ccatcccgtt atcgaggaag gtctgcgtac cgcgttgcgc gatgccgatg cgaaattgaa
     9001 agcctgaccg atatggcaaa acaatgccgt ctgaaatttt ttcagacggc attttgtttt
     9061 tggggatggg gtcggatgct gataccgtgt cgggaagggg gcggcaaaac taaaaatctt
     9121 tcttttaatc tgctgtttcc acgcgtgttt gtcaaaatct atcagtttgt ttttaaaata
     9181 cactgttcaa aatgggataa aacaggtaaa ttaacgttta tgtaacccag tgtagcaatg
     9241 ggtttacggt ttttgagtcg atatataact acagaggaat tgactatgtc tgccaaaccg
     9301 cgtcctgttt atctggattt gccgaacatc cgtctgccga tacccgggat agtttccatc
     9361 cttcaccgca tcagtggggt cgggctgttt attatgctgc ctttcctgct gtatttcctg
     9421 tccggtaccc tgagtcaaga gtctgcattt gaaacttacc gtgccattgt ttcccatcct
     9481 ttggtcaagc tggttttaat cggtgtattg tgggcttatc tgcaccattc tctcgccggt
     9541 atccgctttt tatttttgga tgcgcacaaa ggccttgagc tgaatactgc gcgcaatacc
     9601 gctaaagccg tatttgcttc tgcattggtt ttgactgtcg ttttgggagc gttgttatgg
     9661 tagaacgtaa attgaccggt gcccattacg gtttgcgcga ttgggcgatg caacgtgcga
     9721 ctgcggttat tatgttgatt tataccgttg cacttttagt ggttctattt tccctgccta
     9781 aagaatattc ggcatggcag gcatttttta gtcaaacttg ggtaaaagta tttacccaag
     9841 tgagcttcat cgccgtattc ttgcacgctt gggtgggtat ccgcgatttg tggatggact
     9901 atatcaaacc cttcggcgtg cgtttgtttt tgcaggttgc caccatcgtc tggctggtcg
     9961 gctgcttggt gtattcaatt aaagtaattt gggggtaagt atgggttttc ctgttcgcaa
    10021 gtttgatgcc gtgattgtcg gcggtggtgg tgcaggttta cgcgcagccc tccaattatc
    10081 caaatccggt ctgaattgtg ccgttttgtc taaagtgttc ccgacccgtt cgcataccgt
    10141 agcggcgcag ggcggtattt ccgcctcttt gggtaatgtg caggaggacc gttgggactg
    10201 gcacatgtac gataccgtga aaggttccga ctggctgggc gaccaagatg cgattgagtt
    10261 tatgtgccgc gctgcgcctg aagcggtgat tgagttggaa cacatgggta tgccttttga
    10321 ccgtgtggaa agcggtaaaa tttatcagcg tcctttcggc ggccatactg ccgaacacgg
    10381 taaacgcgcg gtagaacgcg cctgtgcggt tgccgaccgt acaggtcatg cgatgctgca
    10441 tactttgtac caacaaaacg tccgtgccaa tacgcaattc tttgtggaat ggacggcaca
    10501 agatttgatt cgtgatgaaa acggcgatgt cgtcggcgta accgccatgg aaatggaaac
    10561 cggcgaagtt tatattttcc acgctaaagc tgtgatgttt gctaccggcg gcggcggccg
    10621 tatttatgcc tcttctacca atgcctatat gaataccggc gatggtttgg gtatttgcgc
    10681 gcgtgcaggt atcccgttgg aagacatgga attctggcaa ttccacccga ccggcgtggc
    10741 aggtgcgggc gtgttgatta ccgaaggcgt acgcggcgag ggcggtattc tgttgaatgc
    10801 cgacggcgaa cgctttatgg aacgctatgc gccgaccgta aaagacttgg cttctcgcga
    10861 cgttgtttcc cgcgcgatgg cgatggaaat ctacgaaggt cgcggctgcg gtaaaaacaa
    10921 agaccatgtc ttactgaaaa tcgaccatat cggcgcagaa aaaattatgg aaaaactgcc
    10981 gggcatccgc gagatttcca ttcagttcgc cggtatcgat ccgattaaag acccgattcc
    11041 cgttgtgccg actacccact atatgatggg cggtattccg accaactacc atggcgaagt
    11101 tgtcgttcct caaggcgacg aatacgaagt gcctgtaaaa ggtctgtatg cggcaggtga
    11161 gtgcgcttgt gcttccgtac acggtgcgaa ccgcttgggt accaactccc tgttggactt
    11221 ggtggtattc ggtaaagctg ccggcgacag catgattaaa ttcatcaaag agcaaagcga
    11281 ctggaaacct ttgcctgcgg atgcgggcga gctgacccgc caacgtatcg agcgtttgga
    11341 caatcaaact gatggcgaaa acgttgatgc attgcgtcgc gaattgcaac gctccgtaca
    11401 actgcacgcc ggcgtgttcc gtactgatga gattctgagc aaaggcgttc gagaagtcat
    11461 ggcgattgcc gagcgtgtga aacgtaccga aatcaaagac aagagcaaag tgtggaatac
    11521 cgcgcgtatc gaggctttgg aattggataa cctaattgaa gtggcgaaag cgactttggt
    11581 gtctgccgaa gcacgtaaag aatcacgcgg tgcgcacgct tcagacgacc atcctgagcg
    11641 cgatgatgaa aactggatga aacatacgct gtaccattca gataccaata ctttgtctta
    11701 caaaccggta cataccaagc ctttgagcgt ggaatacatc aaaccggcca agcgcgttta
    11761 ttgatgcgtt ttcagacggt tttcgcctca taagctcgtc tgaaatctaa ccatacccac
    11821 attgaactgc ttgaatttat aatacaaaat cattgggcag ttgatgagaa aaggaacact
    11881 tctcatggaa aaaatgagtt ttgaaattta ccgttacaac ccggatgttg atgccaagcc
    11941 ttatatgcag cgttacgagt tggaattgga accgaccgac gtgaaacttt tggatgcttt
    12001 ggtacgcctg aaagcacaag acgatacctt gtctttccgc cgctcctgcc gcgaaggcat
    12061 ttgcggttct gacggtatga acatcaacgg caaaaacggc ttggcgtgtt tgaccgatct
    12121 gcgtggcttg aaacagccgg ttaaaattcg tcctctgcca ggtctgcctg ttatccgtga
    12181 cctgattgtg gatatgaccc agttcttcaa acaataccat tccgtcaaac cttatgttgt
    12241 caacgataat ccgattgatg cggacaaaga gcgtctgcaa actcaggaag agcgtaaaga
    12301 gttggacggt ttgtacgagt gtattttgtg cgcctgctgt tcgactgcct gcccgtcatt
    12361 ttggtggaac cctgataaat tcgttggtcc gtccggtttg ctgaatgctt accgcttcat
    12421 tgcggacagc cgagatacca tcactaatga gcgtttggat aatctgaacg acccataccg
    12481 tttgttccgt tgccacacca ttatgaactg cgtagacgta tgtcccaaac acttgaatcc
    12541 gacccgagcc atcggtaaga ttaaagagat tatgttgaaa cgggccgttt aagaaatgat
    12601 ggtttttgac gatattgcca aacggaaaat ccgttttcaa acccgccggg gattgttgga
    12661 gttagattta atcttcggca ggtttatgga aaaagaattc gagcatttga gcgataaaga
    12721 gctgtccgag ttttccgaaa tccttgaatt tcaagatcaa gaattgcttg ccttgattaa
    12781 cgggcattcg gaaacggaca aagggcacct tatcccgatg cttgaaaaaa tcagacgggc
    12841 atgaggcatc tgaaatctgc ctgcaggcag atttcaaaat gcaaaagccg tctgaaggca
    12901 aagaacgtgc tgcggatgca gtaacgtggg ttataacttg caaaggagca ataatatgtc
    12961 caaatcaatc aaactcaacg taccgggtca ggcaggtttg gagctgccgg tattggaagc
    13021 cagcatcggg cacgatgtgg ttgacattcg ggggctgaca aaaaatacag gtttgttttc
    13081 cttcgacccc ggatttgttt caaccgcaag ctgtgagtct aaaattactt acatcgacgg
    13141 cgatcaaggc ttgctttatt atcgcggata ccccatcgag cagctggccg aaaagtccga
    13201 ttatttggaa gtctgctacc tgttgattta cggcgaactg ccgactcccg agcaaaaggc
    13261 agaatttgac aataccgtcc gccgccacac gatggtgcat gaacagctga cttggttctt
    13321 ccggggcttc cgccgcgacg cgcatccgat ggcgatgatg gtcggcgtgg tcggcgcact
    13381 gtctgcgttc taccaagaca gcttggacat tagcaatccc gaacaccgca aaatcgcgat
    13441 ttaccgcctg atttctaaaa tcccgaccat tgcggcaatg tgctaccgct attcaaacgg
    13501 tctgccgttc aattatccga agaataatct ttcttattcc gaaaacttcc ttcatatgat
    13561 gttcgccacg ccgtgtgaag actacaaacc caatcccgtt ttggcacgcg cgctcgaccg
    13621 catctttatt ttgcatgccg accacgagca aaacgcctca acttcaaccg tccgtctggc
    13681 aggctcttcg ggtgcgaatc cgtttgcctg tattgctgcc ggtatcgcct gcctgtgggg
    13741 tgcttcgcac ggcggtgcga acgaagccgt gttgaaaatg ttggacgaaa tcggcgatgt
    13801 gtctaatgtt gccgcataca tggaaggtgt gaaacaacgc aaataccgtc tgatgggctt
    13861 cggtcaccgc gtgtaccgca atatggatcc gcgtgccagc attatgcgcg aaacctgcta
    13921 tgaagttttg aaggaattgg gcttggaaga cagtccgaaa ttcaaactgg cgatggaatt
    13981 ggaacagatt gcgctgaaag acccgttctt tatcgaacgc aaactgtatc caaacgtcga
    14041 tttctattcc ggcatcgtcc tgtccgcgct gggcatcccg accgaaatgt ttaccgtcat
    14101 cttcgccctg tcgcgcagcg tgggctggat ttcgcactgg cacgagatga ttagcgatcc
    14161 ttcgctgaaa atcggccgcc cgcgccagct ttataccggt tcggaacgcc gcgattatgt
    14221 gccgccaggc gagaggtaac atacattaat atattgtcaa acaggcaata tcagagaacc
    14281 ggattgtttc ccgaatccgt ctgattgtag tcggatgaaa tcaagacaag caatccggtt
    14341 taaaataggg tagaataaaa tgtcttttca gacggcatca gtttagccgt caggacgcgg
    14401 acttctaccc tttgtttata ttttaaagaa aagagcgcac gccatgatgg acgaaaaact
    14461 caatttctct tacctgttcg gttcgaacgc accctacatt gaggaattgt acgaggcttt
    14521 tttggaaaac cccgatacgg ttgatgaaaa atggaagcag tatttcaccg atttgagcaa
    14581 acagccgggg acggttgctg tcgatgtcgc acacacaccg attcgcgaat catttgttac
    14641 tttggcgaaa aagaaaattg catctgccgt tgcgggcggt gcggatgagg caatgctgaa
    14701 aaagcaagtc agcgttttac ggctgatttc tgcctatcgt atccaaggcg tgggtgcagc
    14761 ccaacttgat ccgctcaaac gtatcccccc gcgcgatatt gaagccctcg atccgaaatt
    14821 ccacggtctg tctgatgccg atatggcgct tcaattcaat atgggcgagg gcgattttgc
    14881 caatcgcggc aaactgcctt tgtcccaaat catcagcaac ctcaaacaaa cctactgcgg
    14941 ccacatcgca ttggaatata tctatattcc caataccgaa gagcgccgct gggtacgcaa
    15001 ttattttgaa agcgtattgt ccacaccgca ttacaatgcc gatcaaaaac gccgtatctt
    15061 gaaagagatg actgctgccg agactttgga acgttatctg cataccaaat atgtcggtca
    15121 gaaacgtttc ggtgtcgaag gcggcgaaag cgcgattgcc ggtttgaact acctgattca
    15181 aaacgccggt aaagacggcg tggaagaagt catcatcggt atggcgcacc gtggccgtct
    15241 gaatgttttg gtgaacattt tgggcaaaaa acccggcgat ttgtttgccg aatttgaagg
    15301 tcgtgccgaa atcaaactgc ccagcggcga cgtgaaatac catatgggct tcagctccga
    15361 tattgctacc ccgcacggcc cgatgcatgt ttctttggcg ttcaacccgt cccacttgga
    15421 aatcgtcaat ccggtagtgg aaggttctgc acgcgccaag caaaaacgtt tgggcgaaaa
    15481 cggccgcgat aaagtcttgc ccgtattgat tcacggcgac tccgcattta tcggtttggg
    15541 tgtcaaccaa gcgacattca acctgtctaa aacgcgcggt tataccaccg gcggtacggt
    15601 tcatatcgtc atcaacaatc aaatcggctt taccacttcc gatatccgcg atacccgttc
    15661 aaccgtacac tgtaccgata tcgcaaaaat ggtttccgct ccggttatcc atgtgaacgg
    15721 cgatgatcct gagcgtgttt gctttgccat ccaagccgct ttggattacc gcaaaaaatt
    15781 ccataaagac atcgtgattg acgttgtctg ctaccgtaaa tggggtcaca acgagggcga
    15841 tgatccgacc ttgacccaac cgatgatgta caaaaaagta tcgcaacacc ccggtgcgcg
    15901 tgctttgtac accgagcaac tgattgccga aggcgtggta acccaagccg aggcagacgg
    15961 ttacatccaa gcctaccgtg atgctttgga caaaggcgaa cacgtcgagc aaacaacgtt
    16021 gagcaacttt caacgcacgc aaatcgactg gagcaaatac caaggcaaag attggcgcga
    16081 acacatcgaa accggtttgc ctgccgcaga tattgagcgt ctcactgaga agtttaccgc
    16141 cgtaccggaa ggctttgccc tgcatccgac tgcaaaacgt gtgattgaag cgcgtaaagc
    16201 catggcatcc ggcaaacagg ccatagattg gggtatggcc gaaaccttgg catacgccag
    16261 cctcgtaacc aaaggtcatg gcgtgcgtat ctccggtgag gactccggcc gcggtacgtt
    16321 ctcgcaccgc cacgccgtat tgcacgatca aaaacgcgaa aaatgggacg acggtactta
    16381 tgttcccctg cgccatatgg gcgaaggaat gggcgagttc ctggttatcg actccatctt
    16441 gaacgaagag gccgtgatgg cgttcgagta cggctttgcc tgctccgctc ctgacaagct
    16501 caccatttgg gaagctcaat tcggtgactt cgccaacggc gcgcaagtga ctattgacca
    16561 attcctgtct tcaggcgaaa ccaaatgggg tcgcttgtgc ggtctgacca ccatcctgcc
    16621 gcacggttac gacggtcaag gccctgagca ctcttctgca cgcgtagaac gctggttgca
    16681 actgtgttct gagaacaata tgcaagtcat catgccatct gaagcgtcgc aaatgttcca
    16741 cctcttgcaa cgtcaagtct taggttcata ccgcaaaccg ctggtaattt tcatgtccaa
    16801 acgcctgttg cgattcaaag gggcaatgag cccgctggaa aacttcaccg aaggttcgac
    16861 tttccgtccg gttgtcggcg ataccgccga acgcgcaagc aacgacagcg tgaaacgcgt
    16921 ggtattgtgt gccggtcagg tttactatga cttggaagcc ggtcgagccg aacgtaaact
    16981 ggaagatgat gttgcgattg tccgcgttga gcagctgtat ccgttcccat acgatgaggt
    17041 taaagccgaa ctggcgaaat atccgaacgc aaaatctgtg gtttgggcgc aagaagagcc
    17101 gaaaaaccaa ggcgcgttct accaaatccg ccaccgcatc gaagacgtta tcagcgaaga
    17161 gcaaaaactg tcttatgccg gtcgtccaag cagcgcatcg cctgcagtgg gctactcaag
    17221 caaacacatt gctcaattga aacaattggt tgaagacgct ttggcgttgt aaaccaagca
    17281 gcattccgtc tgaggctgct caggcggaat gcccatatgc agaatgaaaa acacacaaca
    17341 ggccgtctga aagggccatt ggagacacaa aatgattatt gatgtaaaag tacctatgct
    17401 gtctgaaagc gtatctgaag gcacgctctt ggaatggaag aaaaaagttg gcgaagcagt
    17461 tgcccgtgac gaaatcctga tcgatatcga aacggacaaa gtggttttgg aagtaccttc
    17521 tccacaagcc ggcgtattgg ttgaaatcgt agcgcaagac ggtgaaaccg ttgttgccga
    17581 ccaagttttg gcacgtatcg ataccgctgc tactgccgct gctgaagcac ctgccgccgc
    17641 tcctgccgaa gctgccccgg ccgccgctcc tgctgctgca caaaacaacg ccgctatgcc
    17701 tgccgccgcc aaactggctg cagagagcgg tgttgacgtg aacgcattgc aaggttccgg
    17761 ccgtgacggt cgcgtattga aagaagacgt acaaaatgcc gcagccaaac ctgccgcagc
    17821 cgctgctcct gccgttgcac ttcctgccgg cgcacgtcct gaagaacgcg taccgatgag
    17881 ccgcctgcgt gcccgtgttg cagaacgcct cttggcttct caacaagaaa acgccattct
    17941 gactacattc aacgaagtca acatgaaacc aatcatggac ttgcgtgcga agtacaaaga
    18001 aaaattcgag aaagaacacg gcgtgaaact gggctttatg tccttcttcg ttaaagccgc
    18061 tgttgcagcc ctgaaaaaat acccggttgt gaatgcttct gttgacggca aagacattgt
    18121 gtaccacggc tacttcgaca tcggtatcgc gattggcagc ccacgcggtt tggttgtgcc
    18181 aatcctgcgc gatgccgacc aaatgagcat tgccgacatc gaacaagcaa ttgttgatta
    18241 cgcgaaaaaa gccaaagacg gcaaaatcgc tatcgaagat ctgaccggcg gtacattcag
    18301 tattaccaac ggcggtactt tcggttctat gatgtccacc ccgatcatca atccgcctca
    18361 atctgcgatt ttgggtatgc acgccactaa agagcgcgct gtggttgaaa acggccaagt
    18421 tgttgtccgt ccaatgatgt atctggctct gtcttacgac caccgtatca ttgacggccg
    18481 cgaagctgta ttgaccttgg tagccattaa agacgcgttg gaagacccag cccgcctgtt
    18541 gttggatctg taatcgtttc agacggcctt ttatttgtta atgaaaaggc cgtctgaatt
    18601 tttatagtgg attaaattta aaccagtacg gcgttgcctc gccttgccgt actatttgta
    18661 ctgtctgcgg cttcgtcgcc ttgtcctgat ttaaatttaa tccactatat ttagatgtag
    18721 cgtaatgtag tatcgtgcta caataggctc aacaaacgat tgagaccgtc tgaaacattt
    18781 gattcgaatg aatcggcaga tatggacttt cagacggctt tttcttaaaa ccatcaaaac
    18841 gcagtcattc aaaataaaaa agaaacgaaa agtatcgttt ttattttgag atactgctaa
    18901 aagcaaagga tgacacgatg tctcaatatg atgtagtagt gattggtgca ggcccgggcg
    18961 gatacgttgc cgccatccgt gccgcacaac tgggtttcaa aactgcctgt gtcgatgcag
    19021 gcgttaacaa agcaggcaat gcccctgcat tgggcggtac ttgcttgaac gtaggttgta
    19081 tcccttctaa agccctgttg caatccagcg aacatttcca cgcagcgcaa cacgagtttg
    19141 ccgaacacgg tatcactgtc ggcgacgtaa aattcgacgt ggccaaaatg attgagcgca
    19201 aagatgccat cgtaaccaaa ctgaccggcg gcgtgaaatt cctgttccag aaaaacaaag
    19261 taaccagcct gttcggtacg gcttcctttg ccggcaaaaa tggcgatgct taccaaatcg
    19321 aagtcgataa caaaggtgag aaaaccgtta tcgaagccaa acacgtcatc gtagcgaccg
    19381 gttccgtacc gcgtccgctg ccacaagtcg ctatcgacaa tgtgaacgta ttggacaacg
    19441 aaggcgcatt gaacctgacc gaagtacctg ccaaactcgg cgtgatcggt tccggtgtga
    19501 ttggtttgga aatgggttcc gtatggaacc gcgtgggtgc ggaagttacc attcttgaag
    19561 ccgcgccgac cttcctggct gccgccgacc aacaaatcgc caaagaagcc ttcaaatact
    19621 tcaccaaaga gcaaggtctg agcatcgaat tgggcgtgaa aatcggcgac atcaagtctg
    19681 aaggcaaagg tgtttccgtt gcttacgaaa ctgctgccgg cgaagccaaa accgaagtat
    19741 tcgacaaact gatcgttgcc atcggccgta ttccaaacac caaaggcctg aacgccgaag
    19801 ccgtaggctt ggaaaaagac gagcgcggct ttatcaaagt agatggcgaa tgccgtacca
    19861 acctgcctaa cgtatgggca atcggcgacg tggttcgcgg cccgatgttg gcacacaaag
    19921 ccagcgacga aggcgttgcc gttgccgaac gcattgccgg tcaaaaaccg catatcgact
    19981 tcaacaacgt accgttcgtg atttacaccg atcctgaaat cgcttgggtg ggtaaaaccg
    20041 aagagcagct caaagccgaa ggcgtggagt acaaaaaagg tacttcaggt tttggtgcga
    20101 atggtcgcgc attggcaatg ggcaaagcca aaggtacggt taaagtgttg gcagacgcca
    20161 aaaccgaccg catcttgggc gtacacatga ttggtccggt tgtcagcgaa ttgcttaccg
    20221 aaggcgtgac tgcgctcgaa ttcttcgcca gcagcgaaga catcgcccgc attatccatg
    20281 cccacccaac cttgtccgaa gtggttcacg aagctgcatt ggcggccgac aaacgcgctt
    20341 tgcacggttg atagacatta aggcctccga caaattgaat gttccgagag cttcgttttc
    20401 tgatttataa ttccgtcaga caaacaaaca gcatttacat tcgttatgaa caaagaaata
    20461 gtcggtattt tctttatacc gatgggcatc atcagcatgt gtatggccgc attgtggcag
    20521 atgtatgtga tgatgaccga aacttatacg ctcaaccgtt tcaaagataa agaattggtt
    20581 tggcgcgtgg cattgttgtt tatcagtttc agccttgccg tttatctgct ctgtccgaat
    20641 tcgcgtaaaa aaggcattgt cttttttatt ctcgggggag gcggtgcagc catgtatctg
    20701 ctggcgcgga tgtggttgcc tttcagcaag tgaaacgacg attttccgac cgccgaaagg
    20761 tagtctgaaa cgcacgggct tgccatttgg aggcaaactc ggggcattac actaatctaa
    20821 aggagaaatc catgaattta cacgagtatc aggctaaaga actgctggct ggctacggtt
    20881 tgcccgtaca aggcggtatt ttggcacaca acggcgaaga agccgctgca gcttacgaca
    20941 aattgggcgg caaattcgct gttgtcaaag cacaagtaca cgccggcggc cgcggtaaag
    21001 cgggcggcgt aaaagtcgtt aaaagccgcg aagaagctaa agaagtggct gaaagcctga
    21061 ttggcaccaa cttggtaact taccaaaccg atgccaacgg tcaacctgtc aacagcgttt
    21121 tggtttgcga agatatgtat ccggttcaaa ccgagctgta cttgggcgca gtggttgacc
    21181 gttctacccg ccgcgttaca ttcatggctt ctaccgaagg cggtgtggaa atcgaaaaag
    21241 ttgctgccga aactccagaa aaaatcttca aagtaaccgt tgatccgctg gtcggcctgc
    21301 aaccttgcca agctcgcgaa gttgccttcc aactgggctt gaaagacaaa caaatcaacg
    21361 agttcgtcaa actgatgacc ggcgcgtaca aagcgtttgt cgaaaacgac ttcgccctgt
    21421 ttgaagtcaa cccgctggca gttcgcgaaa acggcgcact ggcttgcgtg gacggcaaaa
    21481 tcggcatcga cagcaacgcg ctctaccgcc tgccgaaaat cgccgaattg cgcgacaaat
    21541 ctcaagaaaa cgaacgcgag ctgaaagctt ccgaattcga cctgaactat gttgccctgg
    21601 aaggtaatat cggctgtatg gttaacggtg ccggtttggc gatggccacc atggacatca
    21661 tcaaactgaa aggcggccaa cctgccaact tcttggacgt tggcggcggc gcaaccaaag
    21721 accgcgtggt tgaagcgttc aaactgattc tggaagacaa atccgttcaa ggcgtattga
    21781 tcaacatctt cggcggtatc gtacgttgcg acatgattgc ggaagctatc gtggcagccg
    21841 ttaaagaaat caacgtcgac gttcctgtcg ttgttcgttt ggaaggcaac aacgccgaac
    21901 tcggcgcgaa aatcctgaac gaatcaggcc tgaaactgac ttctgcagac ggcctgaatg
    21961 acgcagccga aaaaattgtt gcagccgtaa acgcctaagg agaaaagaat gagcgtattg
    22021 attaataaag acaccaaagt attggttcaa ggtttcaccg gtaaaaacgg tactttccac
    22081 tccgaacaag ctctggctta cggcactaaa gttgtcggcg gcgttacccc gggcaaaggc
    22141 ggtcaaaccc acctgaacct gcctgtattc aacaccatga aagaagctgt taaagaaacc
    22201 ggcgcggatg catccgtaat ttacgttccc gctccgtttg tgttggattc tatcgttgaa
    22261 gccgttgatt caggcgtagg cttggtcgtt gtgattaccg aaggcgtacc tactttggac
    22321 atgctcaaag ccaaacgtta tttggaaacc aacggcaacg gtacccgttt ggtcggccct
    22381 aactgcccgg gcgtgattac tccgggcgag tgcaaaatcg gtattatgcc gggccacatc
    22441 cacactccgg gccgcatcgg tattatttcc cgttccggta cattgactta cgaagccgtg
    22501 gcacaaacca ccaaactggg cttgggtcaa tcaacctgta ttggtatcgg cggtgacccg
    22561 attcctggta tgaaccaaat cgacgcactg aa
//
