LOCUS       NZ_CP031253.1          22591 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP031253.1 Neisseria lactamica strain M17106 chromosome, complete
            genome.
ACCESSION   NZ_CP031253
VERSION     NZ_CP031253.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:35:21
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 607222
            Orig. end    :: 629813
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22591
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[617222:619813]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12591
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..22591
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22591
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="2"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(278..859)
                     /locus_tag="ctg1_587"
                     /transl_table=11
                     /translation="MNLRDDLQLIYDRIPEGSRVLDLGCGDGELLAALVEHKKCSGYGI
                     EIDTDSVIAAMSRGVNVIQADLEEGLTAFNDQSFDVIVLSQTIQAMQNTEKILRCLMRV
                     AKQAIVSFPNFGYWRNRVQIALGGHMPVSERMPYHWYDTPNIHWCTLKDFDLLCAKNNI
                     RVLERAVMTGNRQVKHFPNLLGSLAFYRVG"
     CDS             complement(856..1995)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_588"
                     /sec_met_domain="Abhydrolase_1 (E-value: 3.3e-34, bitscore:
                     115.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQNASVGIVTPQKIPFEMPLVLENGKTLPRFDLMIETYGKLNAQ
                     KNNAVLICHALSGNHHVAGRHSAEDKYAGWWDNMVGPGKPIDTERFFVVGLNNLGGCDG
                     SSGPLSANPETGREYGADFPVVTVKDWVKSQAALADYLGIGQWAAVVGGSLGGMQALQW
                     AISYPERVRHALVIASAPKLSTQNIAFNDVARQAILTDPDFNEGHYRSHNTVPTRGLRI
                     ARMMGHITYLAEDGLGKKFGRDLRSNGYQYGYGVEFEVESYLRYQGDKFVGRFDANTYL
                     LMTKALDYFDPAADFGNSLTRAVQDVQAKFFVASFSTDWRFAPERSHELVKALIAAQKS
                     VQYIEVKSAHGHDAFLMEDEAYMRAVAAYMDNVYKECQQ"
     CDS             2011..2343
                     /locus_tag="ctg1_589"
                     /transl_table=11
                     /translation="MRQKALLYRKQYDFLTRPGRQPDAFDPHTAAHGSYFSDGFPLPDM
                     IGRLFRIFFFFALAALIINRLFSRRQKRALREVAEISARVLLGAAAATLFWYLFMLYFK
                     HIPDSY"
     CDS             complement(2451..2576)
                     /locus_tag="ctg1_590"
                     /transl_table=11
                     /translation="MQVLSSLKTAKQRHRDCQIVRRRGKVYVICKSNPRFKARQR"
     CDS             complement(2576..2851)
                     /locus_tag="ctg1_591"
                     /transl_table=11
                     /translation="MKPNIHPDNYRTVLFFDSSANEGWLIRSCAETHGKTMVWTDGKEY
                     PLFSLDTSSASHPVYTGKQRNVNTEGRASKFNQRFQSVMSSFRKDK"
     CDS             3051..3929
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MTHFR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_592"
                     /sec_met_domain="MTHFR (E-value: 5.4e-109, bitscore: 360.9,
                     seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIHR
                     LQTLHPKFVSVTYGANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAKDY
                     WDSGIRRIVALRGDEPPGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSAQAD
                     LINLKRKIDAGANHVITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQLGKMA
                     QVTNVKIPSWLSQMYEGLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLNRSELT
                     YAICHILGVRP"
     CDS             4064..6340
                     /locus_tag="ctg1_593"
                     /transl_table=11
                     /translation="MTTLHFSGFPRVGAFRELKFAQEKYWRKEISEQELLAVAKDLREK
                     NWKHQAAANADYVAVGDFTFYDHILDLQVATGAIPARFGFDSQNLSLEQFFQLARGNKD
                     QFAIEMTKWFDTNYHYLVPEFHADTEFKANAKHYVQQLKEAQALGLKAKPTVVGPLTFL
                     WVGKEKGEVAFDRLSLLPKLLPVYVEILTALVEAGAEWIQIDEPALTVDLPKEWVEAYK
                     DVYATLSKVSAKILLGTYFGSVAEHAALLKALPVDGLHIDLVRAPEQPDAFADYDKVLS
                     VGVIDGRNIWRANLNKVLETVEPLQAKLGERLWISSSCSLLHTPFDLSVEEKLKANKPD
                     LYSWLAFTLQKTQELRVLKAALNEGRDSVAEELAASQAAADSRANSSEIHRADVAKRLA
                     DLPANADQRKSPFADRIKAQQAWLNLPLLPTTNIGSFPQTTEIRQARAAFKKGELSAAD
                     YEAAMKKEIALVVEEQEKLDLDVLVHGEAERNDMVEYFGELLSGFAFTQYGWVQSYGSR
                     CVKPPIIFGDVSRPEAMTVAWSTYAQSLTKRPMKGMLTGPVTILQWSFVRNDIPRATVC
                     KQIALALNDEVLDLEKAGIKVIQIDEPAIREGLPLKRADWDAYLNWAGESFRLSSAGCE
                     DSTQIHTHMCYSEFNDILPAIAAMDADVITIETSRSDMELLTAFGKFKYPNDIGPGVYD
                     IHSPRVPTEAEVEHLLRKAIEVVPVERLWVNPDCGLKTRGWKETLEQLQVMMNVTRKLR
                     AELAK"
     CDS             6618..7355
                     /locus_tag="ctg1_594"
                     /transl_table=11
                     /translation="MALQDRTGQKVPSVVFRTRVGDTWKDVSTDDLFKGKKVVVFSLPG
                     AFTPTCSSSHLPRYNELFGAFKENGVDAIYCVSVNDTFVMNAWAAEEESDNIYMIPDGN
                     GEFTEGMGMLVGKEDLGFGKRSWRYSMLVNDGVVEKMFIEPEEPGDPFKVSDADTMLKF
                     VAPDWKAQESVAIFTKPGCQFCAKAKQALQDKGLSYEEIVLGKDATVTSVRAITGKMTA
                     PQVFIGGKYIGGSEDLEAYLAKN"
     CDS             7607..9010
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_595"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.7e-42, bitscore:
                     142.0, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 4.7e-20, bitscore:
                     68.9, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIQADVVVIGGGTAGMGAFRNARLHSDNVYLIENNVFGTTCAR
                     VGCMPSKLLIAAAEARHHALHTDPFGVHLDKDSIVVNGKEVMQRVKSERDRFVGFVVAD
                     VEEWPADKRIMGSAKFIDEHTVQIDDHTQITAKSFVIATGSRPVILPQWQSLGDRLIIN
                     DDVFSWDTLPKSVAVFGPGVIGLELGQALHRLGVKVEIFGLGGIIGGISDPVVSDEAKA
                     VFGEELKLHLDAKTEVKLDADGNVEVHWEQDGEKGVFVAEYMLAAVGRRPNVDNIGLEN
                     INIDKDARGVPVADPLTMQTSIPHIFIAGDASNQLPLLHEAADQGKIAGDNAGRYPNIG
                     GGLRRSTIGVVFTNPQIGFVGLKYAQVAAQYQADEFVIGEVSFKNQGRSRVMLVNKGHM
                     RLYAEKATGRFIGAEIVGPAAEHLAHLLAWAHQMKMTVPQMLDMPFYHPVIEEGLRTAL
                     RDADAKLKI"
     CDS             9286..9663
                     /locus_tag="ctg1_596"
                     /transl_table=11
                     /translation="MSVKPRPVYLDLPSIRLPIPGIVSILHRISGVGLFIMLPFLLYFL
                     SGTLSQESAFETYRAIVSHPLVKLVLIGVLWAYLHHSLAGIRFLFLDAHKGLELNTARN
                     TAKLVFTAALVLTVVLGALLW"
     CDS             9657..9998
                     /locus_tag="ctg1_597"
                     /transl_table=11
                     /translation="MVERKLTGAHYGLRDWAMQRATAVIMLIYTVALLVVLFALPKEYS
                     AWQAFFSQTWVKVFTQVSFIAVFLHAWVGIRDLWMDYIKPFGVRLFLQVATIVWLAGCL
                     VYSVKVIWG"
     CDS             10001..11764
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 407.3; E-value:
                     2.8e-124)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_598"
                     /sec_met_domain="FAD_binding_2 (E-value: 9.3e-123,
                     bitscore: 407.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4e-41, bitscore:
                     137.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFPVRKFDAVIVGGGGAGLRAALQLSKSGLNCAVLSKVFPTRSH
                     TVAAQGGISASLGNVQEDRWDWHMYDTVKGSDWLGDQDAIEFMCRAAPEAVIELEHMGM
                     PFDRVESGKIYQRPFGGHTAEHGKRAVERACAVADRTGHAMLHTLYQQNVRANTQFFVE
                     WTAQDLIRDENGDVVGVTAMEMETGEVYIFHAKAVMFATGGGGRIYASSTNAYMNTGDG
                     LGICARAGIPLEDMEFWQFHPTGVAGAGVLITEGVRGEGGILLNADGERFMERYAPTVK
                     DLASRDVVSRAMAMEIYEGRGCGKNKDHVLLKIDHIGAEKIMEKLPGIREISIQFAGID
                     PIKDPIPVVPTTHYMMGGIPTNYHGEVVIPQGDEYEVPVKGLYAAGECACASVHGANRL
                     GTNSLLDLVVFGKAAGDSMIKFIKEQSGWKPLPADAGELTRQRIERLDNQTDGENVDAL
                     RRELQRSVQLHAGVFRTDAILAEGVKQVMEIAERVKRTEIKDKSKVWNTARIEALELDN
                     LIEVAKATLVSAEARKESRGAHASDDHPERDDENWMKHTLYHSDTNTLSYKPVHTKPLS
                     VEYIKPAKRVY"
     CDS             11884..12591
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 108.7; E-value: 4.8e-34)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_599"
                     /sec_met_domain="Fer2_3 (E-value: 1.6e-32, bitscore: 108.7,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.5e-10, bitscore: 38.5,
                     seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKMSFEIYRYNPDVDAKPYTQRYELELEPTDVKLLDALVRLKAQ
                     DDTLSFRRSCREGICGSDGMNINGKNGLACLTDLRSLKQPVKIRPLPGLPVIRDLIVDM
                     TQFFKQYHSIKPYVVNDNPIDADKERLQTQEERKELDGLYECILCACCSTACPSFWWNP
                     DKFVGPSGLLNAYRFIADSRDTITNERLDNLNDPYRLFRCHTIMNCVDVCPKHLNPTRA
                     IGKIKEIMLKRAV"
     CDS             12595..12843
                     /locus_tag="ctg1_600"
                     /transl_table=11
                     /translation="MMVFDDIAKRKIRFQTRRGLLELDLIFGRFMEKEFEHLSDKELSE
                     FSEILEFQDQELLALINGHSVTDKGHLIPMLEKIRRV"
     CDS             12955..14238
                     /locus_tag="ctg1_601"
                     /transl_table=11
                     /translation="MSKSIKLNVPGQADLELPVLEASIGHDVVDIRGLTKNTGLFSFDP
                     GFVSTASCESKITYIDGDQGLLYYRGYPIEQLAEKSDYLEVCYLLIYGELPTPEQKAEF
                     DNTVRRHTMVHEQLTWFFRGFRRDAHPMAMMVGVVGALSAFYQDSLDITNPEHRKIAIY
                     RLISKIPTIAAMCYRYSNGLPFNYPKNNLSYSENFLHMMFATPCEDYKPNPVLARALDR
                     IFILHADHEQNASTSTVRLAGSSGANPFACIAAGIACLWGASHGGANEAVLKMLDEIGD
                     VSNVAEYMEGVKQRKYRLMGFGHRVYRNMDPRASIMRETCYEVLKELGLEDSPKFKLAM
                     ELEQIALKDPFFIERKLYPNVDFYSGIVLSALGIPTEMFTVIFALSRSVGWISHWHEMI
                     SDPSLKIGRPRQLYTGSERRDYVPAGER"
     CDS             14443..17271
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) E1_dh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_602"
                     /sec_met_domain="E1_dh (E-value: 5.1e-50, bitscore: 167.1,
                     seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 1.1e-63, bitscore:
                     211.1, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMDEKLNFSYLFGSNAPYIEELYEAFLENPDAVDEKWKQYFTDLS
                     KQPGTVAVDVAHTPIRESFVSLAKKKIASAVAGSADEAMLKKQVSVLRLISAYRIQGVG
                     AAKLDPLKRIPPRDIEALDPKFHGLSDTDMALQFNMGEGDFANRGKLPLSQIISNLKQT
                     YCGHIALEYIYIPNTEERRWVRNYFESVLSTPHYNADQKRRILKEMTAAETLERYLHTK
                     YVGQKRFGVEGGESAIAGLNYLIQNAGKDGVEEVIIGMAHRGRLNVLVNILGKKPGDLF
                     AEFEGRAEIKLPSGDVKYHMGFSSDIATPHGPMHVSLAFNPSHLEIVNPVVEGSARAKQ
                     KRLGENGRDKVLPVLIHGDSAFIGLGVNQATFNLSKTRGYTTGGTVHIVINNQIGFTTS
                     DIRDTRSTVHCTDIAKMVSAPVIHVNGDDPERVCFAIQAALDYRKKFHKDIVIDVVCYR
                     KWGHNEGDDPTLTQPMMYKKVSQHPGARALYTEQLIAEGVVTQAEADGYIQAYRDALDK
                     GEHVEQTTLSNFQRTQIDWSKYQGKDWREHIETGLPAADIERLTQKFTAVPEGFALHPT
                     AKRVIEARKAMASGKQPIDWGMAETLAYASLVTKGHGVRISGEDSGRGTFSHRHAVLHD
                     QKREKWDDGTYVPLRHMGEGMGEFLVIDSILNEEAVMAFEYGFACSAPDKLTIWEAQFG
                     DFANGAQVTIDQFLSSGETKWGRLCGLTTILPHGYDGQGPEHSSARVERWLQLCSENNM
                     QVIMPSEASQMFHLLQRQVLGSYRKPLVIFMSKRLLRFKGAMSPLENFTEGSTFRPVIG
                     DTAERASNDSVKRVVLCAGQVYYDLETDRAERKLEDDVAIVRVEQLYPFPYEEVKAELA
                     KYPNAKSVVWAQEEPKNQGAFYQIRHRIEDVISEGQKLSYAGRPSSASPAVGYSSKHIA
                     QLKQLVEDALAL"
     CDS             17371..18552
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) oxoacid_dh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 75.3; E-value:
                     8.6e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_603"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.9e-22, bitscore:
                     75.3, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="oxoacid_dh (E-value: 6.6e-83, bitscore:
                     274.7, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIDVKVPMLSESVSEGTLLEWKKKVGEAVARDEILIDIETDKVV
                     LEVPSPQAGVLVEIVAQDGETVVADQVLARIDTAATAAAEAPVAAPAEAAPAAAPAAAQ
                     NNAAMPAAAKLAAETGVDVNALQGSGRDGRVLKEDVQNAAAKPAAAAAPAVALPASARP
                     EERVPMSRLRARVAERLLASQQENAILTTFNEVNMKPIMDLRAKYKEKFEKEHGVKLGF
                     MSFFVKAAVAALKKYPVVNASVDGKDIVYHGYFDIGIAIGSPRGLVVPILRDADQMSIA
                     DIEQAIVDYAKKAKDGKIAIEDLTGGTFSITNGGTFGSMMSTPIINPPQSAILGMHATK
                     ERAVVENGQVVVRPMMYLALSYDHRIIDGREAVLTLVAIKDALEDPARLLLDL"
     CDS             18812..20245
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_604"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.3e-69, bitscore:
                     230.8, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 1.1e-35, bitscore:
                     119.2, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQYDVVVIGAGPGGYVAAIRAAQLGFKTACVDAGVNKAGNAPAL
                     GGTCLNVGCIPSKALLQSSEHFHAAQHDFAEHGITVGDVKFDAAKMIERKDAIVTKLTG
                     GVKFLFQKNKVTSLFGTASFAGKNGDAYQIEVDNKGEKTVIEAKHVIVATGSVPRPLPQ
                     VAIDNVNVLDNEGALNLTEVPAKLGVIGSGVIGLEMGSVWSRVGSEVTILEAAPTFLAA
                     ADQQIAKEAFKYFTKEQGLSIELGVKIGDIKSEGKGVSVAYQTAAGEAKTEVFDKLIVA
                     IGRIPNTKGLNAEAVGLEKDERGFIKVDGECRTNLPNVWAIGDVVRGPMLAHKASDEGV
                     AVAERIAGQKPHIDFNNVPFVIYTDPEIAWVGKTEEQLKAEGVEYKKGTSGFGANGRAL
                     AMGKAKGTVKVLADAKTDRILGVHMIGPVVSELVTEGVTALEFFASSEDIARIIHAHPT
                     LSEVVHEAALAADKRALHG"
     CDS             20370..20660
                     /locus_tag="ctg1_605"
                     /transl_table=11
                     /translation="MNKEIVGIFFIPAGIISMCMAALWQMYVMMTETYTLNRFKDKELV
                     WRVALLFISFSLAVYLLCPNSRKKGIVFFILGVGGAVMYLLARMWLPFSKQ"
     CDS             20729..21895
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GARS_A"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ligase_CoA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_606"
                     /sec_met_domain="GARS_A (E-value: 4.6e-05, bitscore: 20.2,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Ligase_CoA (E-value: 1.5e-26, bitscore:
                     90.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLHEYQAKELLAGYGLPVQGGILAHNGEEAAAAYDKLGGKFAVV
                     KAQVHAGGRGKAGGVKVVKSREEAKEVAESLIGTNLVTYQTDANGQPVNSVLVCEDMYP
                     VQTELYLGAVVDRSTRRITFMASTEGGVEIEKVAAETPEKIFKVTVDPLVGLQPCQARE
                     VAFQLGLKDKQINEFVKLMTGAYKAFVENDFALFEVNPLAVRENGALACVDGKIGIDSN
                     ALYRLPKIAELRDKSQENERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLKG
                     GQPANFLDVGGGATKDRVVEAFKLILEDKSVKGVLINIFGGIVRCDMIAEAIVAAVKEI
                     NVNVPVVVRLEGNNAELGAKILNESGLKLTSADGLNDAAEKIVAAVNA"
ORIGIN
        1 ggttgcaaat cggattggga cgcggaagac gaagcggcgg atgccgggga cgaagcagcg
       61 gatgcatcga cttctttggt tttatcgtct ttgctcggag aacacgcggt cagcatgatt
      121 gcggtaagcc ataagagaag tgatgaggtt ttatttttca ttctattgtt tccagtatta
      181 aagaggccgt ctgaaaacct accgtttcat ttttcagacg gcctgttgtt aatagaaccg
      241 aagaacctgt tattgccgac aatgttctca acctgtctta cccgacgcgg taaaacgcca
      301 ggctgcccaa caggttgggg aaatgtttga cctgtctgtt gcccgtcatc acggcgcgct
      361 cgaggacgcg gatgttgttt ttggcgcaca acaaatcaaa gtctttgagc gtgcaccaat
      421 ggatattggg cgtgtcatac caatggtagg gcatgcgttc ggaaaccggc atatgtccgc
      481 cgagtgcgat ttggacgcgg ttgcgccagt agccgaaatt cgggaagctg acaatcgcct
      541 gtttggcgac gcgcatcagg cagcgcagga ttttttcggt attctgcatc gcttggatgg
      601 tctggctcaa aacaatcaca tcaaaacttt gatcgttgaa tgcggttaaa ccctcttcca
      661 aatcggcttg gatcacattc acgccgcgcg acatagcggc aatcacgctg tcggtgtcga
      721 tttcgatgcc gtagccgctg cattttttgt gttcgaccaa ggcggcaagc aattcgccgt
      781 cgccgcagcc caagtccaag acgcggctgc cttcgggaat ccggtcgtaa atcagttgca
      841 aatcatcgcg caggttcatt gctgacattc cttataaacg ttgtccatat aagcggcaac
      901 cgcgcgcata taggcttcgt cttccattaa aaaggcatcg tgcccgtgtg cggattttac
      961 ctcgatatac tgcacggatt tttgggcggc aatcagggct ttgaccagtt cgtgcgaacg
     1021 ttcgggcgcg aaacgccagt cggtgctgaa gctggcgaca aagaattttg cctgcacatc
     1081 ctgcacggcg cgggtcaggc tgttgccgaa atccgccgcc ggatcgaaat agtccaaagc
     1141 cttggtcatc agcaaatagg tgttggcatc aaaccgcccg acgaatttgt cgccctgata
     1201 gcgaagatag gattccactt caaattcaac gccatagccg tattgatagc cgtttgaacg
     1261 caaatcgcgt ccgaattttt tgcccaaacc gtcttcggca agataggtaa tgtgccccat
     1321 catacgggca atccgcaaac cgcgtgtggg aacggtattg tggctgcggt aatgtccttc
     1381 gttgaaatcg ggatcggtca aaatcgcctg ccgcgccaca tcgttgaacg cgatattttg
     1441 cgtggaaagc ttcggcgcag acgcaatcac caaggcgtgg cgcacgcgtt cgggatagga
     1501 aatcgcccac tgcaaagcct gcataccgcc caaactgccg ccgacaaccg ccgcccattg
     1561 cccgatgccg agataatcgg caagcgcggc ttgtgatttt acccagtcct tcaccgtaac
     1621 caccggaaaa tccgcgccgt attccctgcc tgtttcgggg ttggcggaca aaggcccgct
     1681 gctgccgtcg cagccgccca gattgttcaa accgaccacg aaaaatcgtt ccgtatcaat
     1741 cggtttgccg ggaccgacca tattgtccca ccagcccgca tatttatcct ccgccgaatg
     1801 cctgcccgca acatgatggt tgcccgacag cgcgtggcag attaaaaccg cattgttttt
     1861 ttgtgcattc agtttgccat aagtttcaat cattaaatcg aaacgcggca aagttttacc
     1921 gttttccaaa accagcggca tctcaaacgg aattttttgg ggcgttacaa tgcccaccga
     1981 ggcgttttga ctcatattct gttccaacaa atgcggcaaa aagcgttatt atatcgcaaa
     2041 cagtatgact ttttgacacg gccgggcagg cagccggacg cgtttgaccc ccataccgcc
     2101 gcacacggat catacttttc agacggcttc ccgcttcccg atatgatagg cagacttttc
     2161 cgtatttttt tctttttcgc acttgccgcg ctgattatca accgcctctt cagccgcagg
     2221 caaaagcgcg ccctgcgcga agtcgccgaa atcagtgccc gggtgctgct cggcgcggcc
     2281 gccgcgacgc tgttttggta tctgtttatg ctgtatttca aacacattcc ggattcgtat
     2341 tgacggaaaa aaatgccgtc tgaaacgcta tttttctgtt tcagacggca ttttttgaaa
     2401 agggcttgcg gcaggaggag atttacaacc gaagcaggaa gggcaggggg tcagcgttgg
     2461 cgcgctttaa aacgcggatt gcttttgcag atgacgtaaa ctttgcccct gcgcctgacg
     2521 atttggcagt cgcggtggcg ttgtttggcg gttttgagtg aagacagaac ctgcattatt
     2581 tgtcctttct aaacgatgac atgacggatt ggaaacgttg gttgaatttg ctggcacggc
     2641 cttcggtatt gacgttgcgc tgtttgccgg tatagacggg atgggatgca gaagaagtat
     2701 ccagcgaaaa cagcggatat tctttgccgt ctgtccaaac catcgttttt ccgtgtgttt
     2761 cggcgcaaga acgaatcagc cagccttcat tggcactgct gtcgaaaaaa aggacggtcc
     2821 ggtaattgtc aggatgaata ttcggtttca tatatcgcct tacttgaagt gttataacat
     2881 aacaaacttt atcataattt agaaggcttg tacaagaaaa gcagattgtt tttgcgaaat
     2941 attaaaaatt ttcatcataa acctgaaaat tttgaaattg actcatattc ggtgcaactt
     3001 tattatgtcg cctgaaatat catataaaag ataataaaag gtacacagca atgaattacg
     3061 caaaagaaat caatgcgtta aacaacagcc tttccgattt gaaaggcgac atcaacgttt
     3121 cgtttgaatt tttcccgccg aaaaacgaac aaatggaaac gatgctgtgg gattccatcc
     3181 accgtctgca aaccctgcat cccaagttcg tatccgtaac ttacggcgcc aactccggcg
     3241 aacgcgaccg cacgcacggc atcgtcaaac gcatcaagca ggaaaccggc ttggaagccg
     3301 cgccgcacct gaccggcatc gacgcatccc ccgacgaatt acgccaaatt gccaaagatt
     3361 attgggacag cggcatccgc cgcattgtcg ccctgcgcgg cgacgagccg cccggttatg
     3421 agaaaaaacc gttttacgcc gaagacttgg tcaaactgtt gcgctccgtc gccgacttcg
     3481 acatttccgt agcggcatat cccgaagtac atcccgaagc caaatccgca caagccgacc
     3541 tgattaatct gaaacgcaaa atcgatgcgg gcgcaaacca cgtcatcacc caatttttct
     3601 ttgatgtgga acgctacctg cgcttccgcg accgctgcgt gatgttgggc atcgatgtgg
     3661 aaatcgtccc cggcatcctg cccgttacca atttcaaaca actgggcaaa atggcgcaag
     3721 tgaccaatgt caaaatccca agctggctgt cgcaaatgta tgaaggtttg gacgatgacc
     3781 aaggcacgcg caatctggtg gcggcaagta tcgccatcga tatggttaaa gtcctgtccc
     3841 gcgaaggcgt gaaagatttc cacttctaca cgctcaaccg cagcgagctg acttacgcca
     3901 tctgccatat tttaggcgtg cgcccttaaa gccgaaaacg gcttcagacg gcatccaagg
     3961 ccgtctgaaa agcaaaacgc cgccccatct aagccattct gatttacaat accggccgat
     4021 tcggatcgaa ccggtcctta caaaatccaa ctggagagtt tatatgacaa cattacattt
     4081 ttcaggcttc ccgcgtgtcg gcgccttccg cgaattgaaa tttgcccaag aaaaatactg
     4141 gcgcaaagaa atcagcgagc aagaattgct ggctgttgcc aaagacttgc gcgagaaaaa
     4201 ctggaaacac caagctgccg ccaacgccga ttacgttgcc gtaggcgatt tcactttcta
     4261 cgaccacatc ctcgacctgc aagtcgctac cggcgcgatt cccgcccgct tcggcttcga
     4321 cagccaaaac ctgtctttgg aacaattctt ccaactggcc cgtggtaaca aagaccaatt
     4381 cgctatcgaa atgaccaaat ggttcgacac caactaccac tacttggtgc ctgaattcca
     4441 cgccgatact gaattcaaag ccaacgccaa acattacgtc caacaactga aagaagccca
     4501 agccctcggc ttgaaagcca aaccgaccgt tgttggtccg ttgactttcc tgtgggtggg
     4561 taaagaaaaa ggtgaagtcg cattcgaccg tctgagcctg ttgcctaaac tgttgcctgt
     4621 ttacgttgaa atcctgactg cgttggttga agccggtgcc gagtggattc aaatcgacga
     4681 gcctgctttg actgtcgatc tgcctaaaga atgggtagaa gcatacaaag acgtttacgc
     4741 tactttgagc aaagtaagcg ccaaaatcct gttgggcact tacttcggtt ctgttgccga
     4801 acacgccgca ttgctgaaag ccctgcccgt tgacggcctg cacatcgact tggtacgcgc
     4861 tcccgagcaa ccggacgcgt tcgccgacta cgacaaagtc ctgtctgtcg gcgtgattga
     4921 cggccgcaac atttggcgcg ccaacctgaa caaagttttg gaaactgttg agcctctgca
     4981 agccaaactg ggcgagcgtt tgtggatttc cagctcttgc tcgctgttgc acactccgtt
     5041 tgacttgtca gttgaagaaa aactgaaagc caacaaaccc gacctgtact cttggttggc
     5101 atttaccctg caaaaaaccc aagaattgcg cgttctgaaa gccgcattga acgaaggtcg
     5161 tgattctgtt gccgaagaac tcgccgccag ccaagctgcc gccgactccc gtgccaacag
     5221 cagcgaaatc caccgtgcag acgttgccaa acgcctggcc gatttgcctg ccaacgcaga
     5281 ccaacgcaaa tccccatttg ccgaccgtat caaagcgcaa caagcatggt tgaacctgcc
     5341 cctgctgccg acgaccaaca tcggttcttt cccgcaaact accgaaattc gtcaagcacg
     5401 cgccgccttc aaaaaaggcg aactgtctgc cgccgattac gaagccgcga tgaaaaaaga
     5461 aatcgccttg gtggttgaag aacaagaaaa actggacttg gacgtactgg tacacggcga
     5521 agccgagcgt aacgacatgg tcgaatactt cggcgaattg ttgagcggtt ttgcattcac
     5581 ccaatacggc tgggtacaaa gctacggctc acgctgcgtg aaaccaccga ttatcttcgg
     5641 tgacgtaagc cgtcctgaag ccatgactgt cgcttggtct acttacgctc aaagcctgac
     5701 caaacgcccg atgaaaggta tgttgaccgg ccctgtaacc attctgcaat ggtctttcgt
     5761 ccgcaacgat attccccgcg ctaccgtgtg caaacaaatc gcactggctc tgaacgacga
     5821 agtattggat ctggaaaaag caggcatcaa agtcatccaa atcgacgaac ctgccatccg
     5881 cgaaggcctg cctttgaaac gtgccgattg ggatgcctac ctgaactggg ccggcgaatc
     5941 tttccgtctg tcctctgccg gttgtgaaga cagcactcag atccacaccc atatgtgcta
     6001 ctccgagttc aacgacatcc tgccggccat cgcagctatg gatgccgacg tgattactat
     6061 cgaaacttca cgttccgata tggaactcct gaccgcgttc ggcaagttca aatacccgaa
     6121 cgacatcggc ccgggcgttt acgacatcca cagcccgcgc gtaccgactg aagccgaagt
     6181 ggaacacctg ttgcgtaaag ccatcgaagt cgtaccggtt gagcgtctgt gggtgaatcc
     6241 tgactgcggc ctgaaaacac gcggctggaa agaaactctg gaacaactcc aagtgatgat
     6301 gaacgtaacc cgcaaactgc gtgccgaact ggcgaaataa gccggaaccg tatgaacaaa
     6361 tgccgtctga aagcccttca gacggcattt tgccctgagt tgcggcgcaa gggtgcagtt
     6421 gccgggaaat tttctcattg cagcttgtat tcctccaatt tgactttata tattggaaac
     6481 agcaaaccag agttgtattc gatagtttta aataatttat attatttgaa ctataaatta
     6541 tacaaatcat tttgcttggg gtagaatgcc cagcgattca caattatttc tcaaacctat
     6601 ctattaagga gctcaaaatg gctttgcaag atcgtaccgg tcaaaaagta ccttccgtag
     6661 tattccgtac ccgcgtcggc gacacttgga aagatgtgtc taccgatgat ttgttcaaag
     6721 gcaaaaaagt agtcgtattc tctctgcccg gcgcatttac tccgacttgt tcttcttccc
     6781 acctgccgcg ttacaacgaa ttgttcggcg cgttcaaaga aaacggcgtt gatgcaatct
     6841 actgcgtatc tgtaaacgat actttcgtga tgaacgcttg ggctgccgaa gaagaatcag
     6901 acaacatcta catgattcct gacggtaacg gcgaattcac cgaaggtatg ggtatgttgg
     6961 tcggtaaaga agacttgggc ttcggcaaac gctcttggcg ttactccatg ctggttaacg
     7021 acggcgtggt tgaaaaaatg ttcatcgagc cggaagaacc gggcgatccg ttcaaagtat
     7081 ccgatgcaga tactatgctg aaattcgttg ctcccgattg gaaggctcaa gagtctgtgg
     7141 caattttcac taaacccggc tgccaattct gcgccaaagc caaacaagct ctgcaagaca
     7201 agggcttgtc ttacgaagaa atcgtattgg gcaaagatgc aaccgttact tccgttcgcg
     7261 ccattaccgg caagatgact gctcctcaag tcttcatcgg cggcaaatac atcggcggca
     7321 gcgaagattt ggaagcttac ttggctaaaa actaattgcc tgatgcttaa gacggtttga
     7381 acgaagctgt ctgaacagaa aaatagagtt attcagacga tacgctacat ggtcgttctg
     7441 aataactcta tatttacaag tagaatttga gattattgtt ttaaatcgaa acttttaaaa
     7501 tggctattgg ttttatattg tcgatagttt attaaaagcc gtctgaaaac ctgatacgca
     7561 tcacgctgat gctgcttcgg acgcttaata aagaaggaca aagattatga aaaaaattca
     7621 agcagatgtc gtcgtaatcg gcggcggtac tgccggtatg ggcgcgtttc gcaatgcccg
     7681 tttacattcg gataatgttt atctgattga aaacaacgtg ttcggcacaa cctgcgcgcg
     7741 tgtgggctgt atgccttcca aactcttgat tgccgccgca gaagcgcgcc accacgcact
     7801 gcataccgac ccgttcggcg tgcatttgga caaagacagc atcgtcgtca acggcaaaga
     7861 agtcatgcag cgcgtcaaat ccgagcgcga tcgttttgtc ggctttgtcg ttgccgatgt
     7921 ggaagaatgg cctgccgaca aacgcatcat ggggtcggct aaatttatcg acgaacatac
     7981 cgttcaaatc gacgaccata ctcaaatcac ggcaaaaagt ttcgtgattg ctaccggttc
     8041 gcgtcccgtc atcctgccgc agtggcagtc tttgggcgac cgtttgatta tcaacgacga
     8101 cgttttctcg tgggatacgc tgcctaagag cgttgccgtg ttcgggccgg gcgttatcgg
     8161 tttggaactg ggtcaggcat tgcaccgttt gggcgtgaaa gtcgagattt tcggcttggg
     8221 cggcatcatc ggcggcattt ccgaccccgt cgtttcagac gaggcgaaag ccgtgttcgg
     8281 cgaagaattg aaactgcatc tggatgccaa aaccgaggtc aaactcgacg cagacggcaa
     8341 tgtagaagtc cattgggagc aggatggcga aaaaggcgta tttgttgccg aatatatgct
     8401 ggcagccgta ggccgccgtc cgaacgtgga caatatcggt ttggaaaaca tcaatatcga
     8461 taaagacgcg cgcggcgtac ccgttgccga tccgctgact atgcagacca gcattccgca
     8521 tatcttcata gcgggcgatg cgtccaacca actgcccctg ctgcacgaag ccgccgacca
     8581 aggcaagatt gccggcgaca atgcgggacg ctatccgaat atcggcggcg gtttgcgccg
     8641 cagcaccatc ggcgtggtgt ttaccaatcc gcaaatcggc tttgtcggtt tgaaatacgc
     8701 gcaggttgcc gcgcaatacc aagccgacga atttgtcatc ggcgaagtat cgttcaaaaa
     8761 ccaaggccgt agccgcgtga tgctggtaaa caagggccat atgcgcctgt atgccgaaaa
     8821 agccaccggc cgcttcatcg gtgcggaaat cgtaggccct gcggctgaac atttggcgca
     8881 tttgttggct tgggcacatc aaatgaagat gaccgttccg caaatgctgg atatgccgtt
     8941 ctaccatccc gttatcgagg aaggtttgcg taccgccttg cgcgatgccg atgcgaaatt
     9001 gaaaatttga ttaatgtgtg aagaatgccg tctgaaattt ctcagacggc attttatctt
     9061 tccgtaattg aaattgatgt tgatatttca ggcaagggga aagggcgtat cagaaatccg
     9121 ttttttaatc tgctgttttc acgcgtgttt gtcaaaatct atcagtttgt ttttaaaata
     9181 cactattcaa aatgagataa aacaggtaaa ttaacgttta tgtagcccgg tgtagcaatg
     9241 ggcttacggt ttttgagtcg atatataact acagaggaat tgactatgtc tgtcaaaccg
     9301 cgtcctgttt atctggattt gccgagcatc cgtctgccga tacccgggat agtttccatc
     9361 cttcaccgca tcagcggggt cgggctgttt attatgctgc ctttcctgct gtatttcctg
     9421 tccggtaccc taagtcaaga atctgcattt gaaacttacc gcgctattgt ttcccatcct
     9481 ttggtcaagc tggttttaat cggtgtgttg tgggcttatc tgcaccattc ccttgccggt
     9541 atccgctttt tatttttgga tgcgcacaaa ggccttgagc tgaatactgc gcgcaatacc
     9601 gctaaattgg tgtttactgc tgcgctggtg ttgactgtcg ttttgggagc tttattatgg
     9661 tagaacgtaa attgaccggc gcccattacg gtttgcgcga ttgggcaatg cagcgtgcga
     9721 ctgcggttat tatgttgatt tataccgttg cacttttggt ggttctgttt gccctgccta
     9781 aagaatattc ggcgtggcag gcatttttta gtcaaacttg ggtaaaagtg tttacccaag
     9841 tgagcttcat cgccgtattt ttgcacgctt gggtaggtat ccgcgatttg tggatggact
     9901 atatcaaacc cttcggcgtg cgtttgtttt tgcaggttgc caccatcgtt tggctggccg
     9961 gctgcctagt gtattcagtt aaagtgattt gggggtaagt atgggttttc ctgttcgcaa
    10021 gtttgatgcc gtgattgttg gcggtggtgg tgcaggttta cgcgcagccc tccaattatc
    10081 caaatccggt ctgaattgtg ctgttttgtc taaagtattc ccaacccgtt cgcatactgt
    10141 agcggctcaa ggcggtattt ctgcttcatt gggtaatgtg caggaagacc gttgggattg
    10201 gcacatgtac gataccgtga aaggttccga ctggttgggc gaccaagatg cgattgagtt
    10261 tatgtgtcgc gccgcgcctg aagccgtaat cgagttagaa cacatgggta tgccttttga
    10321 ccgtgtggaa agcggtaaaa tctaccaacg tcctttcggc ggacatactg ccgaacacgg
    10381 caagcgcgcg gtagaacgtg catgtgcggt tgccgaccgt accggtcatg cgatgctgca
    10441 tactttgtac caacaaaacg tccgtgccaa cacacaattc tttgtggaat ggacggcgca
    10501 agatttgatt cgcgatgaaa acggcgacgt ggtcggtgta accgccatgg aaatggaaac
    10561 cggcgaagtg tatattttcc acgctaaagc cgtgatgttt gccaccggcg gcggtggccg
    10621 tatttatgct tcttctacca atgcctatat gaataccgga gacggtttgg gcatttgcgc
    10681 ccgtgcaggt attccgttgg aagacatgga attctggcaa ttccatccga ccggtgtggc
    10741 aggtgcgggc gtgttgatta cagaaggcgt acgcggcgag ggcggtattc tgttgaacgc
    10801 cgacggcgaa cgctttatgg aacgttatgc gcctaccgta aaagacttgg cttcacgcga
    10861 tgtggtttcc cgcgcgatgg cgatggaaat ctacgaaggt cgcggctgcg gcaaaaacaa
    10921 agaccacgtt ctgctgaaaa tcgaccatat tggcgcagaa aaaattatgg aaaaactgcc
    10981 gggcatccgt gagatttcca tccagtttgc cggtatcgat ccgattaaag acccgattcc
    11041 ggttgtaccg actacccact atatgatggg cggcattccg accaattacc acggcgaagt
    11101 tgttattccg caaggagacg aatacgaagt gcctgtaaaa ggtctgtatg cggcgggcga
    11161 gtgcgcctgc gcttccgtgc acggtgcgaa ccgcttgggt accaactccc tgcttgactt
    11221 ggtggtattc ggtaaagctg ccggcgacag tatgattaaa ttcatcaaag agcaaagcgg
    11281 ctggaaaccc ctgcctgccg atgcgggtga gttgacccgc caacgtatcg aacgcttgga
    11341 caatcaaacc gatggtgaaa acgttgatgc attgcgtcgc gaactgcaac gttccgtcca
    11401 actgcatgcc ggcgtgttcc gtaccgatgc gattttggca gagggcgtga aacaggttat
    11461 ggagattgcc gagcgcgtga aacgcaccga aatcaaagac aagagcaaag tgtggaacac
    11521 cgcgcgtatc gaggctttgg aattggataa tctgattgaa gtagcgaaag cgactttggt
    11581 gtccgccgaa gcacgtaaag aatcccgtgg cgcacacgct tcagacgacc atcctgagcg
    11641 cgatgatgaa aactggatga aacatacgct gtaccattca gataccaata ccttgtctta
    11701 caaaccggtg cataccaagc ccttgagcgt ggaatacatc aaaccggcca agcgcgttta
    11761 ctgatgcgtt ttcagacggc ctttacctca aaggccgtct gaaacttaac catacccaca
    11821 ttgaactgtc tgaatccata atacaaaatc attgggcagt tgatgagaaa aggaacactt
    11881 ctcatggaaa aaatgagttt tgaaatttac cgttacaacc cggacgttga tgccaagcct
    11941 tatacgcagc gttacgagtt ggaattggag ccgaccgatg tgaaactttt ggacgcttta
    12001 gtgcgtctga aagcgcaaga cgataccttg tctttccgcc gatcctgccg cgaaggtatt
    12061 tgcggttcgg acggtatgaa cattaacggc aaaaacggct tagcgtgcct gaccgattta
    12121 cgcagtctga aacaaccggt caaaatccgc ccccttccgg gtctgcccgt catccgtgac
    12181 ttgattgtgg atatgaccca gttcttcaaa caataccatt ccatcaaacc ttatgtcgtt
    12241 aacgacaatc cgattgatgc ggacaaagag cgtctgcaaa ctcaggaaga gcgcaaagag
    12301 ttggacggct tgtacgaatg tattttgtgc gcctgctgtt cgaccgcctg cccgtcgttc
    12361 tggtggaatc ccgacaaatt cgtcggcccg tccggtttgc tgaatgctta ccgtttcatt
    12421 gcggacagcc gcgataccat taccaacgag cgtttggata atttgaacga cccataccgt
    12481 ttgttccgtt gccataccat tatgaactgt gtggacgtat gccccaaaca cttgaatccg
    12541 acccgggcca tcggtaagat taaagagatt atgttgaagc gggccgttta agaaatgatg
    12601 gtttttgacg atattgccaa acggaaaatc cgttttcaaa cccgccgggg attgttggaa
    12661 ttagatttaa tcttcggcag gtttatggaa aaagaattcg agcatttgag cgataaagag
    12721 ctgtccgagt tttccgaaat ccttgaattt caagatcaag aattgcttgc cttgattaac
    12781 gggcattcgg taacggataa aggacacctt atccctatgc ttgaaaaaat cagacgggta
    12841 tgaagtatct gaaatctgcc tacgggcaga tttcaaaatg caaaggccgt ctgaaagcaa
    12901 agaaggtgct gcggatgcag caacgtgggt tacaacttgc aaaggagcga taatatgtcc
    12961 aaatcaatca aactcaacgt gccgggtcaa gcagacttgg agctgccggt attggaagcc
    13021 agcatcggtc acgatgtggt tgacattcgg gggctgacaa aaaatacagg tttgttttcc
    13081 tttgaccccg gatttgtttc aaccgcaagc tgtgagtcta aaattactta tatcgacggc
    13141 gatcaaggct tgctttatta tcgcggatac cccatcgagc agctggccga aaaatccgat
    13201 tatttggaag tctgctatct gttgatttac ggtgaactgc cgactcccga gcaaaaggca
    13261 gaatttgaca ataccgtccg ccgccacacg atggtgcatg aacagttgac ttggttcttc
    13321 cgaggtttcc gccgtgatgc gcatccgatg gcgatgatgg tcggcgtggt cggcgcgttg
    13381 tctgcgttct accaagacag cttggacatt accaatcccg aacaccgcaa aatcgcgatt
    13441 taccgcctga tttccaaaat cccgaccatt gcggcaatgt gctaccgcta ttcaaacggt
    13501 ctgccgttca attatccgaa aaataatctt tcttattccg aaaacttcct tcatatgatg
    13561 tttgccacac cgtgtgaaga ctataaaccc aatcccgttt tggcacgcgc gctcgaccgc
    13621 atctttattt tgcatgccga ccacgagcaa aacgcctcaa cttcaaccgt ccgtctagca
    13681 gggtcttcgg gtgcaaaccc gtttgcctgt atcgctgctg gtatcgcctg cctgtggggt
    13741 gcttcgcacg gcggtgcgaa tgaagccgtg ttgaaaatgc tggacgaaat cggcgatgtg
    13801 tctaatgttg ccgaatatat ggaaggtgtg aaacagcgca aataccgtct gatgggcttc
    13861 ggtcaccgcg tgtaccgcaa catggatccg cgtgccagca ttatgcgcga aacctgctat
    13921 gaagttttga aagaattggg tttggaagac agtccgaaat tcaaactggc gatggaattg
    13981 gaacaaattg cactgaaaga cccgttcttt atcgaacgca agctgtatcc aaacgtcgat
    14041 ttctattccg gcatcgtcct gtccgcgctg ggcatcccga ccgaaatgtt taccgtcatc
    14101 ttcgccctgt cgcgcagcgt aggttggatt tcgcactggc acgagatgat cagcgatcct
    14161 tcgctgaaaa tcggccgccc gcgccagctt tataccggtt cggaacgccg cgattatgtg
    14221 ccggcaggag agaggtaaca tacattaata tattgtcaaa caggcaatat tagagaatcg
    14281 gattgctttc tgtacacatt tgattgtagt cggatgaaat caatacaggc aatccggttt
    14341 aaaatagggt agaataaaat gtcttttcag acggcatcag ttcagccgtc aggacgcgga
    14401 cttctaccct ttgtttatat tttaaagaaa agagcgcacg ccatgatgga cgaaaaactc
    14461 aatttctctt acctgttcgg ttcgaacgca ccttacattg aggaattgta cgaggctttt
    14521 ttggaaaacc ccgatgcggt ggatgaaaaa tggaagcagt atttcaccga tttgagcaag
    14581 cagccgggga cggttgctgt cgatgtcgca cacacaccga ttcgcgaatc atttgtttct
    14641 ttggcgaaaa agaaaatcgc atctgccgtt gcgggcagtg cggatgaggc aatgctgaaa
    14701 aagcaagtca gcgttttacg gctgatttct gcttatcgta tacaaggcgt gggtgcagcc
    14761 aaacttgatc cgctcaagcg tatcccgccg cgcgacattg aagccctcga tccgaaattc
    14821 catggtctgt ctgataccga tatggcgctc caattcaata tgggcgaggg cgattttgcc
    14881 aatcggggca aactgccttt atcccaaatc atcagcaacc tcaaacaaac ctactgcggc
    14941 cacatcgcat tggaatatat ctatattccc aataccgaag agcgtcgttg ggtacgcaat
    15001 tattttgaaa gcgtattgtc cacaccgcac tacaatgccg atcaaaaacg ccgtatcttg
    15061 aaagaaatga ctgctgccga aactttggaa cgctacctgc ataccaaata tgtcggccaa
    15121 aaacgctttg gtgtagaagg cggcgaaagc gcgattgcag gtttgaacta cctgattcaa
    15181 aacgccggta aggacggcgt ggaagaagtc atcatcggta tggcgcaccg aggccgtctg
    15241 aatgttttgg tgaacatttt gggcaaaaaa cccggcgatt tgttcgctga gtttgaaggc
    15301 cgtgccgaaa tcaaactgcc cagcggcgac gtgaaatacc atatgggctt cagctccgat
    15361 attgccacgc cgcacggccc gatgcacgtt tctttggcgt tcaacccgtc acacttggaa
    15421 atcgtcaatc cggtagtgga aggttctgca cgcgccaagc aaaaacgttt gggcgaaaac
    15481 ggccgcgata aagtcttgcc cgtattgatt cacggcgact ccgcatttat cggtttgggt
    15541 gtcaaccaag cgacattcaa cctgtctaaa acgcgcggtt ataccaccgg cggtacggtt
    15601 cacatcgtta tcaacaacca aatcggcttt accacttccg atatccgcga tacccgttca
    15661 accgtacact gtaccgatat cgcgaaaatg gtttccgccc cggttatcca cgtcaacggc
    15721 gatgatcccg aacgcgtttg ctttgccatc caagccgctt tggattaccg caaaaaattc
    15781 cataaagaca tcgtgatcga cgttgtctgc taccgtaaat ggggccacaa cgagggcgac
    15841 gatcctacct tgacccaacc gatgatgtat aaaaaagtat cgcaacatcc gggtgcgcgt
    15901 gctttgtata ccgagcaact gattgccgaa ggcgtggtaa cccaagccga ggctgacggt
    15961 tacatccaag cctaccgtga tgctttggac aaaggcgaac acgtcgagca aacaactttg
    16021 agcaatttcc aacgcacaca aatcgattgg agcaaatatc aaggtaaaga ttggcgcgaa
    16081 cacatcgaaa ccggtttacc tgccgcagac attgagcgtc ttacccaaaa atttaccgcc
    16141 gtgccggaag gctttgccct gcatccgact gcaaaacgcg tgattgaagc gcgtaaagcc
    16201 atggcatccg gcaaacagcc tatcgactgg ggtatggcgg aaaccctcgc atatgccagc
    16261 cttgtaacca aaggtcacgg cgtgcgtatt tccggcgagg actcgggacg cggcacgttc
    16321 tcgcaccgtc atgccgtatt gcacgatcaa aaacgcgaaa aatgggacga cggtacttat
    16381 gttcctctgc gccatatggg cgaaggaatg ggcgaattcc tcgttatcga ctccattttg
    16441 aacgaagaag ccgtgatggc gttcgagtac ggctttgcct gctccgcacc tgacaagctg
    16501 accatttggg aagctcaatt cggtgacttc gccaacggcg cgcaagtgac gattgaccaa
    16561 ttcctgtctt cgggcgaaac caagtggggt cgtttgtgcg gcctgaccac catcctgccg
    16621 cacggttacg acggtcaagg tcccgagcac tcttctgcac gcgtagaacg ttggttgcaa
    16681 ctgtgttccg agaacaatat gcaagtcatc atgccgtctg aagcgtcgca aatgttccac
    16741 ctcttgcaac gccaagtttt gggttcatac cgcaaaccgc tggtgatttt catgtccaaa
    16801 cgcctgttgc gcttcaaagg tgcaatgagt ccgctggaaa acttcaccga aggttcgact
    16861 ttccgtccgg ttattggcga taccgcagaa cgcgcaagca acgacagcgt gaaacgcgtg
    16921 gtattgtgtg ccggtcaggt ttactatgac ttggaaaccg accgtgccga acgtaaactg
    16981 gaagatgatg ttgcgattgt tcgcgttgag cagctgtatc cgttcccata cgaagaggtt
    17041 aaagccgaac tggcgaaata tccgaacgca aaatctgtgg tttgggcaca agaagagccg
    17101 aaaaaccaag gtgcgttcta ccaaatccgc caccgcatcg aagacgttat cagcgaaggg
    17161 caaaaactgt cttatgccgg tcgtccaagc agcgcatcgc ctgcagtggg ctactcaagc
    17221 aaacacattg cccaattgaa acaattggtt gaagacgctt tggcgttgta agccaagcag
    17281 cattccgtct gaggctgctc aggcggaatg cccatatgca gaatgaaaaa cacacaacag
    17341 gccgtctgaa agggccattg gagacacaaa atgattattg atgtaaaagt acctatgctg
    17401 tctgaaagcg tatctgaagg cacgctcttg gaatggaaga aaaaagttgg cgaagcagtt
    17461 gcccgtgacg aaatcctgat cgatatcgaa actgacaaag tggttttgga agtaccttct
    17521 ccacaagccg gcgtattggt tgaaatcgta gcgcaagacg gtgaaaccgt tgttgccgac
    17581 caagttttgg cacgtatcga taccgctgct actgccgctg ccgaagcacc cgtagccgct
    17641 cctgccgaag ccgccccggc cgccgctcct gctgctgcac aaaacaacgc cgctatgcct
    17701 gccgccgcca aactggctgc cgagaccggc gttgacgtga acgcattgca aggttccggc
    17761 cgtgacggtc gcgtattgaa agaagacgta caaaatgccg ctgccaaacc tgccgcagcc
    17821 gctgctcctg ccgttgcact gcctgccagc gcacgtcctg aagaacgcgt accgatgagc
    17881 cgcctgcgtg cccgtgttgc agaacgcctc ctggcttctc aacaagaaaa cgccattctg
    17941 actacattca acgaagtcaa catgaaaccg atcatggact tgcgtgcgaa gtacaaagaa
    18001 aaattcgaga aagaacacgg cgtgaaactg ggctttatgt ccttcttcgt taaagccgct
    18061 gttgccgccc tgaaaaaata cccggttgtg aatgcttctg ttgacggcaa agacatcgtg
    18121 taccacggct acttcgatat cggtatcgca attggcagcc cacgtggttt ggttgtgcca
    18181 attctgcgcg atgccgacca aatgagcatt gccgacatcg aacaagcaat tgttgattac
    18241 gcgaaaaaag ccaaagacgg caaaatcgct atcgaagatc tgaccggcgg tacattcagt
    18301 attaccaacg gtggtacttt tggttctatg atgtccaccc cgatcatcaa cccgcctcaa
    18361 tctgcgattt tgggtatgca cgccactaaa gagcgcgctg tggttgaaaa cggccaagtt
    18421 gttgtccgtc caatgatgta tttggctttg tcttacgacc accgtatcat tgacggccgc
    18481 gaagccgtat tgaccttggt agccattaaa gacgcgttgg aagacccggc acgcctgttg
    18541 ttggatctgt aatcgtttca gacggccttt tatttgttaa tgaaaaggtc gtctgaattt
    18601 ttatttagat gtagcgtaat atagtatcgt gctacaatag gctcaacaaa cgattgaggc
    18661 cgtctgaaac atttgattcg aatgaatcgg taggtatgga ctttcagacg gccttttctt
    18721 aaaaccatca aaacgcagtc attcaaaata aaaaagaaac aaaaagtatc gtttttattt
    18781 tgagatactg ccaaaagtaa aggatgacac gatgtctcaa tatgatgtag tagtgattgg
    18841 tgcaggcccg ggcggatacg ttgccgccat ccgtgccgcg caactgggtt tcaaaaccgc
    18901 ttgcgtcgac gcaggcgtta acaaagctgg caatgcccct gcattgggcg gtacttgctt
    18961 aaatgtaggt tgtatccctt ccaaagccct gttgcaatcg agcgaacatt tccacgctgc
    19021 gcaacatgat tttgccgaac acggtatcac tgtcggcgac gtaaaattcg acgcggccaa
    19081 aatgattgag cgcaaagatg ccatcgtgac caaactgacc ggcggcgtga aattcctgtt
    19141 ccaaaaaaac aaagtaacca gcctgttcgg tacggcttcc tttgccggta aaaatggcga
    19201 tgcctaccaa atcgaagtcg ataacaaagg cgagaaaacc gttatcgaag ccaaacacgt
    19261 catcgtagcc accggttccg taccgcgtcc gctgccacaa gtcgctatcg acaatgtgaa
    19321 cgtattggat aacgaaggcg cattgaacct gaccgaagtg ccagccaaac tcggcgtgat
    19381 cggttccggc gtgattggtt tggaaatggg ttccgtatgg agccgcgtgg gttcagaagt
    19441 taccattctt gaagctgcgc cgaccttcct ggctgccgcc gaccaacaaa tcgccaaaga
    19501 agccttcaaa tactttacca aagagcaagg cttgagcatt gaattgggcg tgaaaatcgg
    19561 tgacatcaaa tctgaaggca aaggcgtgtc tgttgcctac caaactgccg caggcgaagc
    19621 caaaaccgaa gtattcgaca aactgatcgt tgccatcggc cgtattccaa ataccaaagg
    19681 cctgaacgcc gaagctgtcg gcttggaaaa agacgagcgc ggttttatca aagtagatgg
    19741 cgaatgccgt accaacctgc ctaacgtatg ggcaatcggc gacgtggttc gcggcccgat
    19801 gttggcacac aaagccagcg acgaaggtgt tgccgttgcc gagcgcattg ccggtcaaaa
    19861 accgcatatc gacttcaaca acgtaccgtt tgtgatttac accgaccctg aaatcgcttg
    19921 ggtgggtaaa accgaagagc agctcaaagc cgaaggcgtg gagtacaaaa aaggtacttc
    19981 aggtttcggt gcgaatggtc gcgcattggc catgggcaaa gccaaaggta cggttaaagt
    20041 attggcagat gccaaaaccg accgcatctt gggcgtacac atgattggcc cggttgtcag
    20101 cgaattggtt accgaaggcg tgactgcgct cgaattcttc gccagcagcg aagacatcgc
    20161 ccgcattatc catgcccacc caaccttgtc cgaagtggtt cacgaagctg cattggcggc
    20221 cgacaaacgc gctttgcacg gttgatagac attaaggccg tctgaaactt ttcagacggc
    20281 cttaaggcct ccgacaaatt gaatgttccg agagcttcgt tttctgattt ataattctgt
    20341 caggcaaaca aacagcattt acattcatta tgaacaaaga aatagtcggt attttcttta
    20401 taccggcggg catcatcagt atgtgtatgg ccgcattgtg gcagatgtat gtgatgatga
    20461 ccgaaactta tacgcttaac cgtttcaaag ataaagaatt ggtttggcgc gtggcattgt
    20521 tgtttatcag tttcagcctt gccgtttacc tactctgtcc gaattcgcgt aaaaaaggca
    20581 tcgtcttttt tattctcgga gtcggcggtg cagttatgta tttgttggcg cggatgtggc
    20641 tgcctttcag taaacaatag tgccgtctga aaatatagga ttgtccgcag ggcgattcct
    20701 aagacccact caccttaagg agaaatccat gaatctacac gagtatcagg ctaaagaact
    20761 gctggctggc tacggtttgc ccgtacaagg cggtattttg gcacacaatg gcgaagaagc
    20821 cgctgcagct tatgataaat tgggcggcaa attcgctgtt gtcaaagcac aagtacacgc
    20881 cggcgggcgc ggtaaagcgg gcggcgtaaa agtcgtcaaa agccgcgaag aagccaaaga
    20941 agtggctgaa agcctgattg gcaccaactt ggtaacttac caaaccgatg ccaacggcca
    21001 acctgtcaac agcgttttgg tttgcgaaga catgtatccg gttcaaaccg agctgtactt
    21061 gggcgcagtg gttgaccgtt ctacccgccg cattacattc atggcttcta ccgaaggcgg
    21121 cgtggaaatc gaaaaagttg ctgccgaaac tccagaaaaa atcttcaaag taaccgttga
    21181 tccgctggtc ggcctgcaac cttgccaagc tcgcgaagtt gcgttccaac tgggcttgaa
    21241 agacaaacaa atcaacgagt tcgtcaagct gatgaccggt gcgtacaaag cgtttgtcga
    21301 aaacgacttc gccctgtttg aagtaaaccc gctggcagtt cgcgaaaacg gcgcactggc
    21361 ctgcgtggac ggcaaaatcg gcatcgacag caacgcactc taccgcctgc cgaaaatcgc
    21421 cgaattgcgc gacaaatctc aagaaaacga acgcgagctg aaagcttccg aattcgacct
    21481 gaactatgtt gccctggaag gcaacatcgg ctgtatggtg aacggtgccg gtttggcgat
    21541 ggccactatg gacatcatca aactcaaagg cggccaacct gccaacttct tggacgttgg
    21601 tggcggcgca accaaagacc gcgtggttga agcgttcaaa ctgattttgg aagacaaatc
    21661 cgttaaaggc gtattgatca acatcttcgg cggtatcgta cgttgcgaca tgattgcgga
    21721 agccatcgtg gcagccgtta aagaaatcaa cgtcaacgtt cctgtcgttg ttcgtttgga
    21781 aggtaacaac gccgaactcg gcgcgaaaat cctgaacgaa tcaggtctga aactgacttc
    21841 tgcagacggc ctgaatgacg cagccgaaaa aattgttgca gccgtaaacg cctaaggaga
    21901 aaagaatgag cgtattgatt aataaagaca ccaaagtatt ggttcaaggt ttcaccggta
    21961 aaaacggtac tttccactcc gaacaagctc tggcttacgg cactaaagtt gtcggcggcg
    22021 ttaccccggg caaaggcggt caaacccacc tgaacctgcc cgtgttcaac accatgaaag
    22081 aagcggttaa agaaaccggc gcggacgcat ctgtaattta tgttcccgct ccgtttgtgt
    22141 tggattctat cgttgaagcg gttgattccg gcgtaggctt ggtggttgtg attaccgaag
    22201 gcgtgccgac tctggacatg cttaaagcca aacgttattt ggaaaccaac ggcaacggta
    22261 cccgcttggt cggccctaac tgcccgggcg tgattactcc gggcgagtgc aaaatcggca
    22321 ttatgccggg ccacatccac actccgggcc gcatcggcat catttcccgt tccggtacat
    22381 tgacttacga agccgtggca caaaccacca aactgggctt gggccaatca acctgtatcg
    22441 gtatcggcgg cgacccgatt cccggtatga accaaatcga cgcactgaaa ctcttccaag
    22501 aagacccgga taccgacgcc atcatcatga tcggtgaaat tggcggtact gcggaagaag
    22561 aagcagccga atacatccaa tccaacgtaa c
//
