LOCUS       NZ_CP018630.1          24761 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP018630.1 Clostridium chauvoei strain 12S0467 chromosome,
            complete genome.
ACCESSION   NZ_CP018630
VERSION     NZ_CP018630.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:09:08
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2734245
            Orig. end    :: 2759006
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24761
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2744245:2749006]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14761
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..24761
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24761
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="acetate2butyrate"
                     /region_number="6"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             complement(619..1476)
                     /locus_tag="ctg1_2478"
                     /transl_table=11
                     /translation="MGNILSTREMLKKAQREGYAVPAFNIHNLETLQVVVETAAELKSP
                     VILAGTPSTIVYAGGEYIVAMAEVAAKKYDIPVAIHLDHYEDVDAIKHYVDLGFKSTMI
                     DASHEEYERNIEIVKDVVNYAHRFDATVEAELGRLGGQEDDLVVDEKDAMYTNPEQAKD
                     FVDRTGVDSLAIAIGTAHGLYKGVAKLDFERLKEIRAIVDVPLVLHGASDVPDELVKKA
                     ISLGICKVNVATDLKIPFSDAVKKYFIENPEANDPRKYMTPGKEAMKKIVAHKIMVCGS
                     NGRA"
     CDS             complement(1503..1934)
                     /locus_tag="ctg1_2479"
                     /transl_table=11
                     /translation="MVGLIVTGHGNFATGLLSSLKLIAGEQENLIGVDFTVDDNTETLE
                     VKLRNAINTLGEEIVVLSDLAGGSPFKVSVVLSQQLQDKKIRVISGTNLGMILEVSLCR
                     EGMAADELVDFAINSGKSAIKAFEIKVEEETEEDEFDGI"
     CDS             complement(1983..3146)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SIS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2480"
                     /sec_met_domain="SIS (E-value: 9.8e-17, bitscore: 58.3,
                     seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFFGLTKERLQEIGATFTATEVRQQPETWRKTYEIIKENKENIEN
                     FLKKNLKANTRIILTGAGTSDYVGDTIYLYLAKKLKVRVEAIATTDLVSNPHEFVEEDT
                     PTILVSYARSGNSPESVGAYEVFEKNVKNITQLVITCNKGGQLAKKATQNEKNLCLLMP
                     EESNDKSFAMTSSFSCMLLASLLVFDIENIEENKKYVNTVINQGNYILDNKWEDIKSLV
                     ELGCERVVYLGSGALKGLCQEMALKNLELTSGKTITVCESVLGFRHGPKSIINDNTLVI
                     FMNSTNEYTNLYDMDLIKEIHGDVGKHKLAVISYKDNEELNNLCDKYLSINGAEVPEIY
                     TVFNYMLFGQMFGLFSSLNLGISPDNPRPDGTVNRVVKGVIIHPYSK"
     CDS             complement(3230..3958)
                     /locus_tag="ctg1_2481"
                     /transl_table=11
                     /translation="MGVIDKSSRIPLYLQLMDILIENIDKNLEEHQQIISEREICETYD
                     VSRTTVRQALDELERDGYIYKVHGKGTFVSPKRLNQDLMSFYSFTEEMKKIGKEPTSEV
                     IGFEIIHTDEKLSRIFKIKETDLLYKITRIRKADNIPMMYEITYLPFERFEGLTKAELE
                     KSPMYDVLIGKFLAKLTAAEEYFEPILTNKLESIYLDINEGEPSLKIERFTYENSKLVE
                     YTIGVARGDKFKYRVQLKNN"
     CDS             complement(4125..4943)
                     /locus_tag="ctg1_2482"
                     /transl_table=11
                     /translation="MESNLGYKNPSTDKVITKKDLNAMAWKSLFLQASFNYERMQACGW
                     LYSLLPGLKKIHTNKEDLSASMKDHLEFFNTHPFLVTFIMGLIIAMEENKEDRNTIRAI
                     KVATMGPLGGIGDALFWLTALPICAGIGASLAKEGNVAGPIIFLVLFNIIHFGLRFFLM
                     NYGYNTGVKAVATLKEQTKKISHAASIVGLTVVGGLIASMVNLKTTLVITAGQAEVVLQ
                     EGVLDAVMPNLLPLAYTFLMYSLLKKGKSPVMLILFTIVFGIAGKFLGIL"
     CDS             complement(4933..5700)
                     /locus_tag="ctg1_2483"
                     /transl_table=11
                     /translation="MFVQALLIAIWAGIAGIDMFDGLTHIHRPIVTGLIVGLILGDMKT
                     GLIVGATLELVWMGMVPLAGAQPPNVVIGGIIGTSLAIIGKLDAQAAVGLAVPFAVAAQ
                     AGITLLFTAFSPIMHKADKYAEEANTNGINKINYLGLVILFVSYFICAFLPIYFGSDKA
                     AEIVQMIPQPIIDGLSVAGGIMPAIGFAMLLKIMLKKEYITFLLGGFLLVTYFKIPILA
                     LALIGLCIALYDYHNSKNNQTVQVVKEEFEDGI"
     CDS             complement(5793..6269)
                     /locus_tag="ctg1_2484"
                     /transl_table=11
                     /translation="MPNILLTRVDNRLIHGQVGVTWVNHLGANLILVANDKVSADPVQQ
                     SLMDMVVPDAIQTRFFSIEKTIKVINKASAKQKIFLVCKTPQDALRLVEGGVPIKEINI
                     GNMHFSEGKEQISSTVSIDEDDKKTLRKLIDLGVKVEQRRVPDERPEIDIAKFV"
     CDS             complement(6559..7119)
                     /locus_tag="ctg1_2485"
                     /transl_table=11
                     /translation="MNYLILSVLLLLLVFIATLSFTMVANKNNSFKENIRFSGMMLAVS
                     LPIISLVGGTLFLIFKLVSMVVPMQIDTIQVFLIALIGVFIIFACDLVSKQILAGISSR
                     IFATKYKNQDLTEKEMLDIINKSQGIFNIFELVIMFFTSAILYLGVMKLISIDINLIFL
                     SIISLMNVISYRVFFRSKISTGN"
     CDS             complement(7234..8190)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BcrAD_BadFG"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2486"
                     /sec_met_domain="BcrAD_BadFG (E-value: 5e-39, bitscore:
                     131.7, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYLGIDGGGTKTRYILVDDKLEKVGDVESGTIHIHQVGVEGIKK
                     ELRENISKICSNVNIEPKDIAFIFAGVPGYGESLEDKVKIDQAIREVMEAPYMIDNDAV
                     NGWAAGTACKAGINVVAGTGSIAYGRNDEGMLARCGGFGPGIGDDGSAYWIGLRTINEY
                     TKQRDGREEKTALLDVLEREYNISYDYEIVDIVFNKLQRDRTKLATFSKICFLAAEEGC
                     PVARKIFEDVAEELFKHIRSLSKTLKFDGKFVVSYTGGVFKAGKYVLEPLKAKVEAAGL
                     DCIIQEPELDPWNGAALLAYKLAGNEVPSNVKEIMCD"
     CDS             complement(8437..9381)
                     /locus_tag="ctg1_2487"
                     /transl_table=11
                     /translation="MDFKEVIFEDNKVILKGMKNFNIKQILECGQCFRWDKITDTNYIV
                     VACGRVIEVQQNENEVIILNANKEDFNNIWISYFDLERDYSVIKRELAKDEILKKSVEF
                     GYGIRILNQDPFEMLISFIISARNSIPSIKKTVKKICEIWGEKIIYNDQEYYTFPRPEQ
                     IKEATLEEIQATGASFRSKYIISTINNVNEALRVKKDMISNPDKYKERPEILDYDLEYI
                     SNLNDDECHIALQKFMGVGAKVSDCIMLFSMAKHSAFPVDVWVKRAMIHFYVAPDVSLN
                     KMRIFAREKFGSLSGMAQQYLFYYARENNIKVD"
     CDS             complement(9451..9882)
                     /locus_tag="ctg1_2488"
                     /transl_table=11
                     /translation="MLVEKTRELYDKKHDLNCAECILKAANECYDLDLSAQTIKAMAAF
                     GGGMAIESICGGATGAIAAIGIMFTEERGHQSPHVKMMTSEFMSIFRENLGTLNCDELK
                     LKYRENEEDRCLHMMLVAAKSLEEIIEKYKEDYKIIRVK"
     CDS             complement(10001..10849)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2489"
                     /sec_met_domain="HCDH (E-value: 8.2e-38, bitscore: 126.3,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 3.1e-68, bitscore: 226.5,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKIFVIGAGTMGAGIVQAFAQKGYEVIVRDIKDEFVEKGIAGIN
                     KGLSKQVAKGKMTEETKEAILSRITGTTDMKLAEDCDLVIEAAIENMQIKKQIFAELDE
                     ICKESAILASNTSSLSITEVASATKRADKVIGMHFFNPAPVMKLVEIIRGMATSQETFD
                     AVKELSVAIGKEPVEVAEAPGFVVNRILIPMINEATFILQEGIASAEDIDSAMKYGANH
                     PMGPLGLGDLIGLDVCLAIMDVLYNETGDTKYRASSLLRKYVRAGWLGRKSGKGFYDYS
                     R"
     CDS             complement(10929..11936)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 174.6;
                     E-value: 6.4e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2490"
                     /sec_met_domain="ETF (E-value: 2.7e-52, bitscore: 174.6,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 1.7e-37, bitscore:
                     124.6, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIADYRGVWVFAEQREGELQKVSLELLGEGRKIADKLGVKLTAL
                     LLGDNVKALAETLGKHGADEVLVAESELLKNYTTDGYTKVICDLASERKPGIVFIGATF
                     IGRDLGPRVAARLSTGLTADCTGLDVEVENGDLLATRPAFGGNLMATIACPDHRPQMAT
                     VRPGVFSKIPEEARDFNIEEVEVKLSESDIRTKIVEIIKETKDVVDISEANFIISGGRG
                     VGSKENFALLEELAEVLGGTVAGSRAAVDNAWIEKDYQVGQTGKTVRPNIYIACGISGA
                     IQHVAGMQESDMIIAVNKDESAPIMKVADYAIVGDITKVLPEMTAQLKAMKEAE"
     CDS             complement(11958..12737)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 176.8;
                     E-value: 1.4e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2491"
                     /sec_met_domain="ETF (E-value: 5.8e-53, bitscore: 176.8,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVVCLKQVPDTTAVKIDPKTGTLIRDGVPSIINPEDKHALEAA
                     LRIKETSGAHVTVISMGPPQAQNALREALCMGADEAVLITDRAFAGADTLATSKALAGA
                     LKRLEYDIVFAGRQAIDGDTAQVGPEIAEHLHIPQVTYVQDVKVEEDGLLVNRALEDGY
                     ELIKVQAPVLLTAIKELNEPRYMNVKYIFETAGKEIKVWSADDIEVNKAELGLKGSPTK
                     VKKSMTKETKGAGEIVKETAPEAVKYVLGKLKEKHYI"
     CDS             complement(12757..13896)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2492"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4e-52, bitscore:
                     173.7, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 9.8e-27, bitscore:
                     90.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 7.8e-38, bitscore:
                     126.9, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFQLTREQELVRQMVREFAVNEVKPIAAEIDETERFPMENVEKM
                     AKLGMLGIPFSKEYGGAGGDTLAYILAVEELSKVCATTGVILSAHTSLCASLIEQFGNK
                     NQKEKYLPDLATGKKIGAFGLTEPGAGTDAAGQQTVAVLDGDHYVLNGSKIFITNGGVA
                     ETFIIFAMTDKSKGTKGISGFIVEKNFPGFSIGKKEEKLGIRASSTTELVMENCIVPKE
                     NLIGQEGKGFGIAMKTLDGGRIGIAAQALGIAEGALAEAIAYMKERKQFGRPIAAFQGL
                     QWMIAEMDTKIEAARHLVYKAACLKEAKMPYSVDAARAKLYAAEVAMDVTTKAVQIFGG
                     YGYTKEYPVERMMRDAKITEIYEGTSEVQKMVISGSALR"
     CDS             complement(13979..14761)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2493"
                     /sec_met_domain="EC1_2-faecali (E-value: 7.6e-88, bitscore:
                     291.3, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELKNVILEKEGNLAIVTINRPKALNALNSETLKDIDTVISDLEK
                     DSNIYCVILTGAGEKAFVAGADIAEMKELNEEQGREFGLLGNKVFRRLEKLNKPVIAAI
                     SGFALGGGCELSMSCDIRIASEKAKFAQPETGLGITPGFGGTQRLPRLVGEGKAKELIY
                     TGAIIKADEALKIGLVNKVVPLESLMDEARAVAKKIIENAPIAVKLCKDAINRGMQVDI
                     DNAIEIEAGDFGKCFSTEDQFEGMTAFIERRSKNFQNK"
     CDS             complement(15019..15690)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2494"
                     /sec_met_domain="CoA_binding (E-value: 3.3e-21, bitscore:
                     73.1, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKKNISMAVIKRLPKYHRYLQELMRNDVDRISSKELGEKIGFT
                     ASQIRQDLNCFGDFGQQGYGYNVRDLYKQISMILGLNKEYKTLIVGAGNIGQAVANYSR
                     FSELGLNLRGIFDANPKLIGLRMRSIEIQDIDYLESFLKNDSIDIGMICVPRINAQKVC
                     DVLVQGGVKGIWNFAPVDLVVPEDVIVENVHLSESLLTLIYLLHKDDKEDEKKIEDGQD
                     K"
     CDS             complement(16214..18463)
                     /locus_tag="ctg1_2495"
                     /transl_table=11
                     /translation="MKNSNIIKLTLEGLTCANCGNKIEGRVNKLNGVVEANLNFSTSTL
                     IVEIDSSVPKDKIIEEVKDIVKKLEPEVIVLEKGKSKIKRATNKNICKDFCCDIKEGHH
                     NHNHSHSGNCCNEHHHHEDNKKGGHEHEHNHESISFKLKDNWKLIIGAILYIIAMILSK
                     DSIVAAILFVVSYVLIGGGVVYSAFRNIIRGELFDENFLMTVATLGAFFIGEFPEGVAV
                     MLFYQIGEMFQGYAVNRSRKSITSLMDIRADYANLLVGDKDTKVSPEDVSVDDIIIIKP
                     GERVPLDGVVIEGSSLVDTSALTGESVPREIKVDEQILAGCINNNGVLKVKVTKGFGES
                     TVSRILELVENASSKKAPTEKFITKFSKIYTPIVVFLALGLALIPPLVISNATFDVWIY
                     RASIFLVVSCPCALVISVPLVLFAGIGGASKKGILVKGGNYLEALKDVDTVVFDKTGTI
                     TKGVFKVTEVNPINIDSDKLLEIAALGEVFSNHPIAQSIVKAYGKEINKDNIKEYEEVS
                     GHGIKVSIDDEEILLGNYKLMKKFNIQYEEVDSIGTIVYIAINKEYKGNIIISDEIKKE
                     AKEAIKELKENGINRVVMLTGDNKVVAEKVAKSVGIDNVYSELLPVDKVEKIEGLLKEG
                     SNVSKVAFVGDGINDAPVLARADIGVAMGNIGSDAAIEAADIVLMNDEPQALVEAIKVA
                     KKTNKVLWQNIIFALGIKIFVLLLGAFGVATMWEAVFADVGVTILAVLNSTRCLK"
     CDS             complement(18478..18837)
                     /locus_tag="ctg1_2496"
                     /transl_table=11
                     /translation="MEEKKTEACTCNIIHKNIVDKVRKSIPDEEILYDVADLFKAFSDS
                     TRIKIICALFQSEMCVCDLAALLGMNQSAISHQLRVLKSSRLVKFRREGKVIYYSLDDE
                     HVKHIFDEGFRHVTE"
     CDS             complement(18961..19554)
                     /locus_tag="ctg1_2497"
                     /transl_table=11
                     /translation="LLMNTHKMLANNFIENVDENKLFLIKESHFVWGNLKPDCASKYKL
                     KKHYFDESFDMIVKKIEFLSSLTVHDIYYRYSINKFNQELGVVCHFLCDYFCVPHNQRW
                     EFKNPNAMKDHIIYEKDLAKVAKEFKITKDINSHLTSEEITKYILKLQDEYEGKIDFNH
                     DLTFAYYVCDSIINMILDEVMLNEKIKEHFSMVI"
     CDS             19836..20051
                     /locus_tag="ctg1_2498"
                     /transl_table=11
                     /translation="MKKKFLTTLLIISISIIFIGCNKNKNTSTKESSGDTISSEEGLLN
                     VEVTLPKSFLVIKMHLQLKQKLKLKE"
     CDS             20093..20431
                     /locus_tag="ctg1_2499"
                     /transl_table=11
                     /translation="MNKSTHKKLLENLKKGTDESIAKIIEDKKNFPSFDNITYNDDLTE
                     FNIFVDKQSYNSIQSLGVLAFYFTGNMYQAMNCVSSDKINTTVNFIDSSTKEVIESGNS
                     KDMGNSFN"
     CDS             20520..20783
                     /locus_tag="ctg1_2500"
                     /transl_table=11
                     /translation="MKKYIIITLALISTLLLGIIIGRFTSPVKEKLIEKEVQKIVEVES
                     PTVGLSKKYLFKFIDIQNEINKLPHNDEKYQTTFGMRELTGK"
     CDS             complement(20984..22051)
                     /locus_tag="ctg1_2501"
                     /transl_table=11
                     /translation="VIYGLILAGGKGTRLYPLSRANKPKQFLKVINNKSFLENTVERII
                     PLIKKENIYVVTNQDYQDKIRLELTDIDNENIFTEPQNKETATCIGLSAVKLLKKDGDA
                     VMVVLPSDHHIDGQKDYIETLSQAVDIANRRRGIVTLGIEPNRPETGYGYIEMGQRIQG
                     ERPSYKVARFTEKPNAEVAKDFLLKGTYLWNSGMFVFRADVILREIEKYLPELYRSLMQ
                     IYKHLGEEDEEQVIREQYDLIDGISIDFGVMQKTRKAYVIKSDFLWDDIGSFSALSRYN
                     DIFRNDTSSNNIYLQECENCSVFAEKNLVIGLGVKDLVIVDAGDVILIMDKNKDQEIKH
                     LLNDLSKEEDYEKFM"
ORIGIN
        1 aattccttct tcttcctctt cttctccttg agctcctcct ggaataggaa cttcacttcc
       61 tattacgtat actggatgta tagcattttc ttcttgttct aatagttcta aatatgattc
      121 ttctgctact ttgcatagaa tagaagctct atttgctatt aatgaatcac caaagattcc
      181 cttctctata tcgcccttca aaggcatact tgtatctata tgaattttag tgaaccctgc
      241 tagtacatac tctctaatta aatctttagc attttccata gcttctatag gagcaatctt
      301 tgtccatgtt aatgggccta aatggtctcc cccaagaatt attctttcta ttggaaaatt
      361 atttttttct gctaactcat gaatatactt aacaaaatcc tttggtttca ttcctgtata
      421 accaccaaat tgatcaactt gatttgcagt tgattcaact aaaagacaca tatccttatc
      481 ctttaatctc tccatagcag cttcaattac atatttattt gaagaacata ctgagaaaat
      541 ccccacattt tccccatttt tatacctagt tactatctcc ttaataggat gtaccatacc
      601 ctcacctctc ataatatatt aagctctgcc gttacttcca cataccatta ttttatgtgc
      661 aactattttc ttcattgctt ctttaccagg tgtcatatat tttcttggat cattagcttc
      721 tgggttttct ataaaatatt tcttaacagc atctgaaaaa ggtatcttta aatcagttgc
      781 tacatttact ttacatattc caagtgaaat agcttttttt actaactcat ctggaacatc
      841 tgaagcccca tgtaatacta gtggaacatc tactatagct ctaatttctt ttagtctttc
      901 aaaatctaat ttagctaccc ctttatataa tccatgagct gttcctatag ctattgctaa
      961 agaatccact cctgttctat caacaaaatc ctttgcttgc tctggatttg tgtacattgc
     1021 atctttttca tctacaacta aatcatcttc ttgtccgcca agtcttccaa gttctgcttc
     1081 tactgttgca tcgaatctat gtgcatagtt gacaacatct ttaactattt caatatttct
     1141 ttcatactct tcatgtgaag catcaatcat agttgattta aatcctaagt caacataatg
     1201 ttttattgca tcaacatctt cataatgatc caagtgaata gctactggaa tatcatactt
     1261 tttggctgca acttcagcca ttgctactat atactctcca ccagcatata ctattgttga
     1321 tggtgtacca gctaatataa ctggtgattt taattctgct gctgtttcta caacaacttg
     1381 aagtgtttct aagttatgaa tattaaatgc tggtacagca tatccttctc tttgtgcttt
     1441 ttttaacatt tctcttgttg ataaaatatt tcccattata atctctccta tactccaatt
     1501 atttaaattc cgtcaaattc gtcttcttct gtttcttctt ctactttaat ttcaaatgct
     1561 ttgattgcac tcttacctga attaatagca aaatccacta actcatctgc agccatacct
     1621 tctctgcata atgaaacttc aagtatcatt cctaggttag ttcctgaaat tactctaatt
     1681 tttttatctt gtaattgttg acttaataca acagatacct taaaaggaga cccccctgct
     1741 aagtctgaaa gcactactat ttcttctcct aatgtattaa ttgcatttct taactttact
     1801 tctaaagttt ctgtattatc atctactgta aaatctactc caattaaatt ttcttgttct
     1861 cctgcaatta atttcaatga acttaaaagt cctgttgcaa aatttccatg ccctgttact
     1921 attagcccta ccataattaa agattcctcc cttatttata aattaatatt cttttgtttt
     1981 atctatttgc tatatggatg tataattaca ccttttacta ctctattaac tgttccatct
     2041 ggtcttgggt tatctggtga aattccaagg tttaatgaac taaataaacc aaacatttga
     2101 ccaaataaca tataattaaa tactgtataa atttctggaa cttctgcacc atttatactt
     2161 aaatatttgt cacataaatt gtttagttcc tcattatctt tataactaat aactgctaat
     2221 ttatgttttc ctacatctcc atgaatttct tttattaagt ccatatcata aaggtttgta
     2281 tattcattag ttgaattcat aaatatcact aatgtattat catttattat tgattttggg
     2341 ccatgtctaa atcctaatac tgactcacaa acagttattg tttttccact tgttaattct
     2401 aagttcttaa gagccatttc ttgacaaagt ccttttaagg ctcctgagcc taaataaact
     2461 actctttcac atcctagttc tactaatgat ttaatatctt cccatttgtt atctaaaata
     2521 taatttcctt gattaattac tgtattaacg tattttttgt tttcttcaat attttcaata
     2581 tcaaaaacta ataatgatgc aagtagcata cagctaaatg aacttgtcat agcaaaactc
     2641 ttatcatttg attcttctgg cataagtaaa caaagatttt tttcattttg tgtagccttt
     2701 ttagcaagtt gccctccctt attacacgta attaccagtt gtgttatatt tttaacattc
     2761 ttttcaaaaa cttcataagc tccaacactt tctggactat ttcctgatct tgcataggat
     2821 actaagatag ttggcgtatc ttcttcaaca aactcatgag gattggacac taaatctgtt
     2881 gttgcaatag cttcaactct tacctttaat tttttagcta aatacagata tattgtatct
     2941 cctacataat cagaagtacc tgctcccgtt aatattattc ttgtattagc ctttaaattc
     3001 ttctttaaaa agttttctat attctcttta ttttccttta ttatttcata agtctttctc
     3061 caagtttcag gttgctgtct aacctctgta gctgtaaaag ttgctcctat ttcttgtaat
     3121 ctttcttttg tcaaaccaaa aaacatctaa actacctccc actactgata atgtcgtcat
     3181 taccagttgt tttaaaaaat tttatttttt atttaaatta agttaataac taattatttt
     3241 ttaattgaac tctatattta aacttatcgc ctctagccac accaatagta tattctacta
     3301 atttactatt ttcataagta aatctttcga ttttcaaact cggttctcct tcatttatat
     3361 ctaaatatat actttctagt ttattagtaa gtataggttc aaaatactct tcagctgctg
     3421 ttaatttagc taaaaatttt cctattaaaa catcatacat aggtgatttt tctaattcag
     3481 cctttgttaa cccttcaaat ctctcaaacg gtaaatatgt tatttcatac atcattggaa
     3541 tattgtctgc ttttcttatt cttgtaattt tatacagtag atctgtctct tttattttaa
     3601 aaatacgaga taacttttca tctgtatgta ttatttcaaa tccaataacc tctgaagtag
     3661 gttctttacc aatctttttc atctcttctg taaaagaata aaatgacatt aagtcttgat
     3721 ttaacctttt tggtgataca aaagttcctt ttccatgaac cttatatata tatccatctc
     3781 tttcaagttc atctaaagcc tgtctcactg tagttctact aacatcgtat gtttcacata
     3841 tctctctttc tgaaataatt tgttgatgtt cttctaggtt cttatcgata ttttctataa
     3901 gtatatccat taattgtaaa tacaatggta tccttgagct tttatcaata actcccattt
     3961 tactaccacc tcattatttt ataccccaat tatatcataa tttttttaaa attccactaa
     4021 tatttatgta atatattaca tacttctaag ttagtcccta tttacccctt taacttttaa
     4081 gacctatatc tagctttcac tagatatagg tctataattt tattttataa tattcctaag
     4141 aatttacctg ctataccaaa tactattgta aataatatta gcataactgg tgatttaccc
     4201 ttcttaagta aagaatacat taagaaagta tatgctaatg gtaaaaggtt tggcattact
     4261 gcatctaaaa ccccttcttg aagaacaact tcagcttgcc cagctgttat aactaaagta
     4321 gtctttaagt taaccattga agctattaat cctccaacaa ctgttaatcc aacaattgaa
     4381 gcagcatgtg atatcttctt agtttgttct tttaatgttg ctacagcttt aacaccagta
     4441 ttgtaaccat agttcattaa gaagaatctt aaaccaaaat gtataatatt gaataatact
     4501 aagaatataa tcggacctgc aacattacct tcttttgcta atgatgctcc gataccagcg
     4561 catattggta aagctgttaa ccagaataat gcatcaccga tacctccaag aggtcccatt
     4621 gttgcaacct tgattgctct tatagtattt ctatcttctt tattttcttc cattgctatt
     4681 attagtccca taatgaatgt tactaagaat ggatgtgtat taaagaattc aagatgatct
     4741 ttcattgaag ctgaaagatc ttctttattt gtatgaatct tctttaatcc tggtagtaag
     4801 gagtatagcc atccacaagc ttgcattctt tcatagttaa atgatgcttg tagaaataat
     4861 gatttccatg ccattgcatt aagatctttt ttagttataa ctttatctgt actcggattc
     4921 ttatatccta aattagattc catcttcaaa ctcctccttt actacttgta ctgtttgatt
     4981 attctttgaa ttgtgataat cataaagtgc tatacataat ccaattaaag caagtgctaa
     5041 gattggaatc ttaaagtaag taactagtaa gaatccacct aataggaaag taatgtattc
     5101 tttctttaac attatcttta atagcattgc aaatccgata gctggcataa ttccacctgc
     5161 tactgataag ccatctataa ttggttgtgg tatcatttga actatttctg ctgctttgtc
     5221 tgaaccaaaa taaattggta agaatgcaca gataaaatat gatacaaata agataactaa
     5281 tcctaaataa tttattttat ttattccatt agtattagct tcttctgcat atttatcagc
     5341 tttgtgcatt attggtgaga aagcagtaaa tagtaatgtt ataccagctt gagcagctac
     5401 tgcaaatgga actgctaaac ctacagctgc ttgggcatca agtttaccta taatagctaa
     5461 gcttgtacca attatccctc caataacaac gtttggtggt tgtgcaccag ctaatggtac
     5521 catacccatc catacaagtt ctaaagttgc accgacaata agtcctgttt tcatgtctcc
     5581 taaaataagt cctacaataa gtcctgttac tattggtctg tgtatgtggg ttaatccatc
     5641 gaacatatcg ataccagcta taccagccca aatagcgatt aatagtgctt gaacaaacat
     5701 ttaaattcat ccccctttta atagattttt ataaatttat gattttaaaa aaatgaaaaa
     5761 ctaatttaaa aggttttaag tattaagtta aactaaacaa attttgctat atcaatttca
     5821 ggtctttcat caggaactct tctttgttct actttaactc ctaaatcgat aagctttctt
     5881 aaagtcttct tatcatcttc atcaattgaa actgttgaag atatttgttc ttttccttca
     5941 ctaaaatgca tatttccaat attaatttct tttattggaa ctccaccttc tactaatctt
     6001 aatgcatctt gaggtgtttt acatactaag aaaatctttt gcttagcaga tgctttattt
     6061 attactttta tagttttttc tattgagaaa aatcttgttt gaattgcatc cggaactacc
     6121 atatccatta aactttgttg tactggatct gcagaaactt tatcattagc aactaaaatt
     6181 aaatttgctc ctaaatgatt tacccaagtt actcctactt gtccatgaat taaacgatta
     6241 tctactcttg ttaataatat gtttggcata actgcacccc cgtaagttct tttaaaatct
     6301 tataatttaa aattatttct aagtggtacg taccacttat ctatattgta aatgttttcc
     6361 gatagcttgt caataatttt attaaatttt caaaatattt attttattca attgttttct
     6421 tatgtaatcc tgtattttaa agggttttta aatgttttta ttttttaaat tcaacttaaa
     6481 aaaagcacca attcattaaa aacgaatcgg tacttcttca catttcgact tactaaacca
     6541 atttaccact atcaactgtt aattaccagt tgatatttta ctcctaaaaa acactctata
     6601 acttataaca ttcatcaatg aaataattga taaaaatatt aaatttatat ctatagaaat
     6661 aagcttcatt actcctaaat ataaaatagc acttgtaaaa aacattatta ctagttcaaa
     6721 gatattaaaa attccttgag acttatttat tatatctagc atttctttct ctgttaaatc
     6781 ttgattttta tactttgttg caaaaattct agaacttatt cctgctaata tttgtttact
     6841 taccaaatca caagcaaata ttataaaaac acctattaac gcaatcaaaa acacctgaat
     6901 tgtatctatt tgcataggta caaccataga aactaattta aatattaaaa acaacgtccc
     6961 tcccactaaa gatataatag gtaaagaaac tgctaacatc attccagaaa atctgatatt
     7021 ttctttaaaa gaattgtttt tattcgcaac cattgtaaat gataaagtcg ctataaaaac
     7081 taataaaagt aataaaacac ttaatattaa ataattcata aacccactcc ctcttatata
     7141 tcccttttat atgtataagc cttacccaat atagtcatta tattaaaggt cacttatctc
     7201 atagaagaat aagtgacctt tatattataa attttaatca cacataattt ctttaacatt
     7261 tgacggaact tcatttccag ctaatttata agctaataat gctgctccat tccaaggatc
     7321 tagttctggt tcttgtatta tacaatctaa ccctgcagct tctaccttcg cctttagtgg
     7381 ttctaataca tattttccag ctttaaatac tccaccagta tatgacacaa caaacttccc
     7441 atcaaacttt aaagtttttg ataatgatct tatatgtttg aatagctctt ctgctacatc
     7501 ttcaaatatt tttctagcaa caggacatcc ttcttctgct gctaaaaaac atatttttga
     7561 aaaagttgca agtttagttc tatctcgttg caatttatta aatactatat caactatttc
     7621 ataatcatat gaaatattat attctctttc taaaacatct aataatgcag ttttttcttc
     7681 tctgccatct ctttgctttg tatattcatt tattgttctt agtccaatcc aatacgcact
     7741 accatcatca ccaattccag gtccaaagcc accacatcta gctaacatac cttcatcatt
     7801 tcttccatag gctatacttc ctgttcctgc aactacatta atacctgctt tacatgcagt
     7861 gcctgccgcc caaccattaa ctgcatcatt atctatcata tatggagctt ccataacctc
     7921 tctaatagct tgatcaattt ttactttatc ttctaaactt tccccatatc caggtactcc
     7981 tgcaaatata aatgcaatat ccttaggttc aatatttaca ttagaacata tttttgaaat
     8041 attttctctt agttcttttt ttattccttc tacacctact tgatgtatgt ggattgtccc
     8101 gctttcaaca tccccaactt tttctaactt atcatcaaca agaatatatc ttgttttggt
     8161 tcctccacca tcaattccta aataatacat acccttctcc tccattgcct attgataaaa
     8221 tattttttgt ggttttcatt ataatttact attactatag tacaatttcc agaaaacctt
     8281 ttcaagtagc ttatatttgt ctatacatta tattttatac tatcttacta taaatatata
     8341 ttactttttt acatttttat aataaagttt acaattccga tttgtaaatt taaattttcg
     8401 ttaataaaaa agtagccttt taaaagctac tttttattaa tctaccttta tgttattttc
     8461 tcttgcataa taaaataaat attgttgtgc catacctgat aaagaaccaa atttttctct
     8521 tgcaaatatt ctcattttat ttaaagaaac atctggtgca acataaaaat gaatcatcgc
     8581 tctttttacc cagacatcca caggaaaggc tgaatgtttt gccatagaaa atagcattat
     8641 acaatctgaa actttagctc caacccccat aaacttttga agagctatat ggcactcatc
     8701 atcatttaga ttgcttatgt attctaaatc ataatccaat atttctggtc tttctttgta
     8761 tttatcagga ttacttatca tatccttttt tactctcaaa gcttcattaa cattattaat
     8821 tgtacttatt atatatttac ttctaaatga agctcctgtt gcttgtattt cttctaaagt
     8881 cgcctcttta atttgttcag gtctaggaaa agtataatat tcttgatcat tatatattat
     8941 tttctctccc catatttcac atattttctt tactgtcttt tttattgatg gaatactatt
     9001 tctagctgat attataaagc taattaacat ttcaaaagga tcttgattta atatcctgat
     9061 tccatatcca aactcaacac ttttctttag tatttcgtct tttgctaatt ccctcttaat
     9121 aacactataa tctctttcta aatcaaaata actaatccaa atattattaa agtcttcttt
     9181 atttgcattc aaaataatta cttcattttc attttgttga acttctataa ctctaccaca
     9241 agctactaca atataattgg tatcggttat cttatcccat ctaaagcatt gaccacattc
     9301 taagatttgt tttatattaa aatttttcat tccttttaat atgaccttat tatcttcaaa
     9361 aataacttct ttaaaatcca tattttcacc tcatgtatta tacatcaata cattaattat
     9421 ccctcaaaaa caagtaaagt attctcccct ttactttact cttattattt tataatcctc
     9481 tttgtatttt tctataattt cttctaatga ttttgcagca actaacatca tatgtaaaca
     9541 tctgtcttct tcattttctc tgtattttaa ctttaattca tcacaattta aagtacctaa
     9601 attctctcta aaaatactca taaattcaga tgtcatcatc ttaacatgtg gactttgatg
     9661 tcccctctct tctgtaaaca taattccaat agcagctata gcaccagtag ctcctccaca
     9721 gatactttct atagccattc ccccaccaaa tgcagccata gctttaatcg tctgagctga
     9781 taggtctaaa tcataacact catttgctgc ttttaatata cattctgcac aatttaaatc
     9841 atgttttttg tcatataatt ctctagtttt ttctactaac atatttcacc tctactattt
     9901 cactttttaa aattatatca tacccaaact atgtatttgt ataatttata aaaaaataag
     9961 agattcatac aagaatctct tacttttaat attaaaaaaa ttatctgcta tagtcgtaga
    10021 atccttttcc tgattttcta cctagccatc cagctctaac atattttctt agtaggctac
    10081 ttgctctata tttagtatct cctgtttcat tatataaaac atccattata gctaaacaaa
    10141 catctaatcc aataagatct cctaaaccta aaggtcccat tgggtgatta gcaccatatt
    10201 tcatagcact atctatatct tcagctgaag caattccttc ttgaagaata aatgttgctt
    10261 cattaatcat tgggataagt attctattaa ctacaaatcc tggagcttct gcaacttcta
    10321 ctggttcttt accaattgct actgataatt ccttaacagc atcaaaagtt tcttgtgaag
    10381 tagccatccc tctgattatt tccactaatt tcattactgg agctgggtta aagaaatgca
    10441 ttcctataac cttatctgct ctctttgttg ctgatgcaac ttcagttatt gataatgatg
    10501 aagtatttga tgctaaaata gctgattctt tacagatttc atctaattca gcaaatattt
    10561 gtttcttgat ttgcatattt tcaattgctg cttctataac taaatcacag tcttctgcta
    10621 atttcatatc agttgttcct gtaattcttg ataatatagc ttccttagtt tcttcagtca
    10681 tctttccttt agctacttgt ttgctaagtc ctttattaat tccagcaatt cctttttcaa
    10741 caaattcgtc ctttatatct ctaacgataa cttcataacc tttttgtgca aaagcttgaa
    10801 caattccagc tcccatagta ccagcaccaa ttacaaaaat cttttccata ataattacct
    10861 cctaaatttt cataccactt gtttttatat tatttatacc ctaaaattca tataatttat
    10921 tgaccttatt attctgcttc cttcatagcc tttaattgag ctgtcatttc aggtaatacc
    10981 ttagtaatat ctccaacgat agcataatct gcaaccttca tgattggagc actttcatcc
    11041 ttattaactg ctataatcat atctgactct tgcatacctg caacgtgttg tatcgctcct
    11101 gaaataccgc atgcaatata gatatttggt cttacagttt taccagtttg acctacttga
    11161 taatcttttt ctatccatgc attatctaca gccgctcttg acccagcaac tgttccccct
    11221 aaaacttctg caagttcttc aagtaatgca aagttttctt ttgaaccaac acctctacca
    11281 cctgatatga taaagttagc ttcacttata tcaacaacat ctttagtttc cttaataatt
    11341 tctacgattt tagttctgat gtcgctttct gataatttaa cttcaacttc ttctatatta
    11401 aaatctctag cttcttctgg aatttttgag aaaactcctg gtcttactgt agccatttgt
    11461 ggtctatgat ctgggcaagc tatagttgcc attaaattac caccaaatgc tggtctagta
    11521 gctaaaagat ccccattttc aacttctaca tctaggcctg tacagtcagc tgttaatcct
    11581 gttgataatc tagctgcaac tcttggacct aaatctctac caatgaaagt tgctcctata
    11641 aatactattc ctggctttct ttcactagct aaatcacaaa ttaccttagt atatccgtca
    11701 gttgtataat tttttaataa ttcactttca gcaactaaaa cctcatcagc accatgctta
    11761 ccaagagttt ctgctaaagc ttttacgtta tctcctaata aaagagctgt taattttacc
    11821 cctaatttat ctgcaatttt tctaccttca ccaagtaatt caagagaaac cttttgaagt
    11881 tctccctctc tttgttcagc aaatacccaa acgcctctgt agtctgctat attcatcttc
    11941 cttacctccc ataattctta gatgtagtgt ttttctttta attttcctaa cacatatttt
    12001 acagcttctg gcgcagtttc ttttacgatt tctcccgcac cctttgtttc ttttgtcatt
    12061 gattttttaa cctttgtagg tgaaccctta agacctaatt ctgccttatt tacttcaatg
    12121 tcatctgctg accaaacttt tatttctttt cctgctgttt caaatatata ttttacattc
    12181 atatatcttg gttcatttaa ttcttttata gctgttaaaa gaactggagc ttgaaccttt
    12241 attaattcat atccgtcttc taaagctcta tttacaagta atccatcttc ttcaactttt
    12301 acatcttgaa cataagttac ttgaggtatg tgtaaatgtt ctgcaatttc tggtcctact
    12361 tgagcagtat ctccatcgat tgcttgtctt cctgcgaata ctatatcgta ttctaatctt
    12421 tttaatgctc ctgctaaagc ctttgaagtt gctaaagtat cagcaccagc aaaagctcta
    12481 tctgtaataa gtactgcttc atcagcaccc atacataatg cttctcttaa agcattttgt
    12541 gcttgtggag gtcccatgct tattacagta acatgagcac cggaagtttc ttttattctt
    12601 aacgcagctt ctaatgcatg cttatcttct ggatttatta ttgaaggaac tccatctctt
    12661 ataagtgttc ctgtctttgg atcaattttt acagctgttg tatctggaac ttgctttaaa
    12721 caaactacta tattcataat ctaagtcctc cccttactat cttaatgcgc ttcctgaaat
    12781 aaccatcttt tgaacttctg aagttccttc gtaaatttca gttatcttag catctctcat
    12841 cattctttct actggatatt ctttagtgta accgtatcct ccaaatattt gaaccgcctt
    12901 agttgtaaca tccattgcaa cttcagcagc ataaagctta gctctagcag catctactga
    12961 ataaggcatc ttagcttctt ttaaacatgc agctttatat actaaatgtc tagctgcttc
    13021 tatcttagta tccatttctg caatcatcca ttgtaatcct tggaatgcag ctatcggtct
    13081 accaaattgt tttctttctt tcatataagc tatagcttct gcaagtgcac cttctgcaat
    13141 acctaaagct tgtgcagcaa taccaattct tcctccatca agagtcttca ttgcgattcc
    13201 aaatcctttt ccttcttgac caattagatt ttcttttggt actatacaat tttccataac
    13261 taattcagtt gttgaagatg ctctaattcc aagcttttct tctttctttc ctattgagaa
    13321 tcctgggaag ttcttttcaa ctatgaaacc tgatattccc ttagttccct tactcttatc
    13381 agtcattgca aaaattataa atgtttcagc aactccacca tttgtaataa atatttttga
    13441 tccatttaac acataatggt caccatctaa aactgctact gtttgttgtc ctgcagcatc
    13501 tgtacctgct cctggttctg ttaaaccaaa tgctccaatc tttttacctg ttgctaaatc
    13561 tggtaaatat ttttcttttt gattcttatt accaaattgt tctattaatg atgcacaaag
    13621 tgaagtatga gctgataata taactcctgt tgttgcacaa acctttgata actcctcaac
    13681 tgctagtata tatgcaagag tatctccacc agctccacca tattctttag aaaatggaat
    13741 tcctagcatt ccaagcttgg ccattttctc aacgttttcc attggaaatc tttctgtttc
    13801 atctatttct gcagcaatcg gctttacttc atttactgcg aattctctaa ccatttgtct
    13861 tactaattct tgttctctag ttaattgaaa attcatttac tatacctcct tgttattaaa
    13921 acctctattc aataataatt ggaaaattac ttcgttatct gtttttttaa tcttctgact
    13981 atttattttg gaaattttta cttcttcttt caataaaggc tgtcattcct tcaaactgat
    14041 cttctgttga aaaacacttt ccaaaatctc ctgcttctat ttcaatagca ttatctatat
    14101 ctacttgcat tcccctatta attgcatctt tacatagttt aactgctatt ggtgcattct
    14161 ctataatctt tttcgcaaca gccctagctt catccattaa actttctagt ggtactacct
    14221 tatttactaa cccaattttt aatgcttcat cagcttttat tattgctcca gtatatatta
    14281 attcttttgc tttaccttct ccaaccaatc ttggtaatct ttgagtacca ccaaatcctg
    14341 gagttattcc aagtcctgtt tctggttgtg caaatttagc cttttctgaa gcaattctta
    14401 tatcacatga catagaaagc tcgcatccac caccaagagc gaaacccgaa atcgctgcaa
    14461 taactggctt gtttaatttt tctaatcttc tgaatacttt gtttccaaga agaccaaatt
    14521 ctcttccctg ttcctcattt aattctttca tttctgcaat atcagcacct gctacaaatg
    14581 ctttttcccc cgcacctgtc aatattacgc agtatatgtt gctatccttt tctaagtctg
    14641 atattactgt atcaatatct tttagagttt ctgagtttaa agcgtttaat gcttttggtc
    14701 tattgattgt aacaatagct aagttgcctt ctttttcaag aattacattt tttaattcca
    14761 tattcaggtc ctccctctca taataaaaaa ttaatacaat tgatgttaac catatttgaa
    14821 catttaattt ttgataaatt cagattgttg aattttgcga aaaaaaattg aacattcaga
    14881 aatctctttt gttaatattg taacaattta ataaaaaaaa ataattgaag caccagcttc
    14941 aattatgatt ataaacttta gatttttgtt ttgcaataac tatttctatt ttatactatt
    15001 ttttacagtt aattatcttt atttatcttg gccatcttca atcttttttt catcttcttt
    15061 atcatcctta tgaagtagat aaattagagt taataagctt tctgataaat gcacattttc
    15121 aactataaca tcttctggta caactaaatc tacaggagca aaattccaga ttccttttac
    15181 cccaccttga actagtacat cacaaacctt ttgtgcattt attcttggaa cacaaatcat
    15241 tccaatgtct atactatcat tttttaggaa tgattctaaa taatctatat cttgaatctc
    15301 tatgcttctc atccttaaac caattagctt tggattagca tcgaatatac ctctaagatt
    15361 taagcctagc tctgaaaatc tactatagtt agctaccgct tgacctatat ttccagcccc
    15421 tactattaat gttttatact ctttatttaa tccaagtatc atgcttattt gtttatataa
    15481 atctcttaca ttgtatccgt atccttgctg tccaaaatct ccaaaacaat ttaggtcctg
    15541 acgtatttga gaagctgtaa atcctatttt ttccccaagt tcttttgatg atattctatc
    15601 gacatcattt ctcatcaatt cctgtaaata tctatggtat ttgggtaatc tcttaattac
    15661 agccatagaa atatttttct ttttttccat actgtaccgt ctccttagcc attattattt
    15721 taaatttctc tatgtatata cataataata tcatatgaaa tccatataat ctatatttta
    15781 acacttttat ataactattt gaatgttttt agttatctat ttaacaaaca ttgtatattt
    15841 tataacctaa atatattttt aaatgtaaag ttaattacct taaataacaa tattgtgtct
    15901 actaaattat taattttcta ttttaattta ttattatttt gcctattatt taaatatatt
    15961 aaacttcaaa atataatatt tttctatatt tagatttgtt tattataaaa aaataagact
    16021 tatgtataac gtagcagatc cgttatacat aagtctatag tatatacaaa gcgtctttca
    16081 gctttgtaac caagatcaga aatcttgtat gcttccctta tgcctgaatg ttctcaacct
    16141 aacttattat atttaatatg atgaattttg tcaatatgtg tactataaat taaatttaat
    16201 ttatatacat ctattattta agacatctag ttgaatttaa aacagctaat atagtaaccc
    16261 caacatctgc aaatacagct tcccacatcg ttgctactcc aaaagctcca agtaacaata
    16321 caaatatttt tattcctaag gcaaatataa tattttgcca taatacttta tttgttttct
    16381 ttgctacttt aattgcttca accaaagcct gtggttcatc attcattaat actatatctg
    16441 cagcttctat tgcagcatcc gaacctatat ttcccatagc tactccaata tcagctcttg
    16501 ctagaactgg tgcatcattt atcccatccc caacaaaagc aaccttgctt acatttgaac
    16561 cttcttttag taagccctca attttttcta ccttatctac tggtagaagt tctgaatata
    16621 cattatctat tcctacactc tttgcaactt tttctgcgac aactttatta tcacctgtta
    16681 acattacaac tctatttatt ccattttctt ttaattcttt tatagcttcc ttagcttctt
    16741 tctttatttc atcagaaata attatatttc ctttatattc tttatttatt gcaatatata
    16801 ctatagttcc aattgaatcc acttcttcat attgaatatt aaacttcttc attaacttat
    16861 agtttcctaa taaaatttcc tcatcatcaa ttgaaacctt tattccatgt cctgatactt
    16921 cttcatactc tttaatatta tctttattta tttcttttcc atatgcttta actattgatt
    16981 gagcaattgg atgattagaa aaaacttcac ctaaagctgc aatttcaagt aatttatcag
    17041 aatctatatt tataggattt acttctgtca ctttaaatac ccctttggtt atagttcctg
    17101 ttttatcaaa aactactgta tctacatcct tcaaggcttc caaataattt ccacccttta
    17161 ctagtattcc ttttttagaa gctccaccaa tacctgcaaa taatactaat ggaacagaga
    17221 taactaatgc acatggacat gatacaacta aaaatattga tgctctataa atccacacat
    17281 caaaagttgc attagaaatt acaagtggtg gaattaaagc taaacctaaa gctaaaaata
    17341 ctactatagg agtatatatt tttgaaaact tagttataaa cttttctgta ggagcttttt
    17401 tgctagatgc attctcaact aattctaata ttcttgatac tgttgactct ccaaaccctt
    17461 tagttacttt tacttttaat actccattat tatttataca acctgctaag atttgctcat
    17521 ctacttttat ctctcttggt actgattcac ctgttaatgc agatgtatct actaaactac
    17581 taccttcaat tacaactcca tctaaaggaa ctctttctcc tggttttata attataatat
    17641 catctacact tacatcttct ggtgatactt tagtatcttt atctccaact aataaatttg
    17701 cataatcagc tcttatatcc attaatgatg ttattgattt tcttgaacga ttaaccgcat
    17761 atccttggaa catttctcca atttgataaa acaacataac tgctacacct tctggaaact
    17821 ctccaataaa gaaagcacct aaagtagcta ctgtcattaa gaaattttca tcaaataatt
    17881 cacctcttat tatatttcta aaggcagaat atacaactcc tcctcctatt aatacataac
    17941 taactacaaa taatatagct gctactatag aatctttaga taaaatcata gctattatat
    18001 ataatatagc acctattata agcttccaat tatcctttaa tttaaagctt atagactcat
    18061 gattatgctc atgttcatgt ccaccttttt tattgtcttc atgatgatga tgttcattac
    18121 aacaattacc actatgagag tgattatggt tatgatgtcc ttctttaata tcacaacaaa
    18181 aatctttgca gatattttta ttagttgctc tttttatctt gcttttaccc ttttctaata
    18241 ctattacttc tggttctaat ttttttacta tatctttaac ttcttctatt attttgtctt
    18301 taggtacact actatcaatt tctactatca atgtagaagt ggaaaagttt aaatttgctt
    18361 ctacaactcc atttaactta tttactcttc cttcaatttt atttccacaa ttagcacaag
    18421 ttaaaccttc caaagtaagc ttaataatat ttgagttttt cattataccc ctccttctta
    18481 ttccgtaaca tgcctaaatc cttcatcaaa aatatgcttt acgtgttcat catctaatga
    18541 ataataaata acttttccct ctcttctaaa tttaactaat ctactagatt ttaaaactct
    18601 taattgatgt gaaatagctg attgattcat tcctaataat gccgctaaat cacaaacaca
    18661 catttcagac tgaaataatg cacagattat ttttattctg gttgaatcac taaaagcttt
    18721 aaataaatct gcaacatcat ataaaatctc ctcatctggg atactttttc taactttatc
    18781 tactatattt ttatgaatta tattacaagt acaagcttca gttttttttt cttccatatt
    18841 ttcctcctta catatgaaca actgctcata tgtttatttg tatttattat attcttatct
    18901 tagtaaaatt gtcaacattt tattattttt tataaataaa aaaagcttgg attatccaag
    18961 ctaaattacc attgaaaaat gttcttttat tttttcattt aacataactt catctaaaat
    19021 catatttatt atgctatcac aaacatagta tgcaaaagtt aaatcatgat taaaatcaat
    19081 tttaccttca tactcgtctt gaagctttaa aatatattta gttatttctt ctgaagttaa
    19141 atgtgaattt atgtcttttg taattttaaa ttctttagct actttagcta aatctttttc
    19201 ataaataata tgatctttca tagcattagg atttttaaac tcccatcttt gattatgtgg
    19261 tacacaaaag taatcacata agaagtgaca aacaactcct agttcttgat taaacttatt
    19321 tattgagtat ctataatata tgtcatgcac tgttaaagaa gataaaaact ctattttctt
    19381 aacaatcata tcaaaacttt catcaaaata atgttttttt aatttatatt ttgatgcaca
    19441 atctggttta agatttcccc aaacaaagtg tgattctttt attaaaaaaa gtttgttttc
    19501 atctacattc tctataaaat tatttgctag catcttgtga gtattcatta gcaattttat
    19561 cacctcactt acatacatct ataatgtata cattaatatt agtcctattt taatattaaa
    19621 acaagtaatt cttatttcat tattatccac aacttagttt acataaaaat gcaactttta
    19681 ttctaaaaaa tctcacttat tattttactc ttttttattc taaaagttcc caaataaata
    19741 aatttttagt gtttttattt actttttgtt ttattatatt aaaatttatt ttattataaa
    19801 ttatttttta atataataag aatggagggg agaatatgaa gaaaaaattt ttaactactt
    19861 tattaataat atcaatttca attatcttta taggatgtaa taaaaataag aatacttcta
    19921 caaaagaatc atctggtgat actatttctt ctgaggaagg cttacttaat gttgaagtaa
    19981 ctttaccaaa aagtttttta gtgataaaga tgcatctaca attgaaacag aagctaaagc
    20041 tgaaggaata aaagatgtta aagtaaataa taatgggtca gtaacttata aaatgaataa
    20101 aagtacgcat aaaaaattat tagaaaatct aaaaaagggt actgatgaat ctattgcaaa
    20161 aataattgaa gacaagaaaa attttccttc ttttgacaat attacttata atgatgattt
    20221 aacagagttt aatatatttg tggataaaca atcttataac tctatacaat cattaggggt
    20281 tttagcattt tattttacag gtaatatgta tcaagctatg aattgcgtaa gctcggataa
    20341 aatcaatact actgtaaatt ttattgactc ttctactaaa gaagtaattg agagtggcaa
    20401 ttctaaagat atgggaaatt cttttaatta agttttttta aaactagctt tgacataaaa
    20461 gctagttttt cataatttat ttactaacta aaaaaatatt ttaaggggga cttactctaa
    20521 tgaaaaaata cataattata accttagctt taatatcaac attattactt ggaattatta
    20581 ttggaagatt tacttctcct gtaaaagaaa agttaattga aaaggaagtt caaaaaatag
    20641 ttgaagttga atctccaact gttggattat ctaaaaaata tttatttaaa tttatagata
    20701 ttcaaaacga aattaataaa ttgcctcata atgatgaaaa atatcaaacc acttttggaa
    20761 tgagagaatt gacaggtaaa taatataaat tgtgggataa tttacttaat gaaatatatt
    20821 cagaattaaa aaatacattg tctactgaaa acatggacta atccttttaa tttttataat
    20881 ataaattact taattaatca tcatattaca atacaaatag acctcttagt aaataattgt
    20941 ttaatcattt actaagaggt ctatttataa ttaatttatt aacttacata aatttttcat
    21001 aatcttcttc tttactcaga tcattaagta aatgctttat ctcttgatct ttatttttat
    21061 ccattattaa tattacatcc cctgcatcaa ctataactaa atctttaaca cctaatccta
    21121 ttacgagatt tttttctgca aatacagaac aattctcaca ttcttgcaaa taaatattat
    21181 tgctagaggt atcatttcta aaaatatcat tatatctact taaagctgag aaacttccta
    21241 tatcatccca taggaaatca ctttttatta catatgcttt tctagtcttt tgcattactc
    21301 caaaatcaat agaaattcca tctattaaat catattgttc tcgaataact tgctcctcat
    21361 cttcttcgcc taaatgctta tatatttgca taagtgacct gtataactca ggaagatatt
    21421 tttcaatctc tcttaatata acatcagctc taaaaacaaa catacccgaa ttccacaaat
    21481 aggttccctt taatagaaaa tcttttgcga cttcggcatt tggtttttct gtaaacctag
    21541 caaccttata acttggacgt tcgccttgta ttctttgtcc catttctata tatccatatc
    21601 cagtttctgg tctattaggt tcaattccta atgttactat acctcttctc ctattagcaa
    21661 tatctactgc ttgtgataat gtttctatat aatctttctg accatctata tgatgatcag
    21721 aaggtaaaac taccataaca gcatctccat cttttttcaa aagtttaacg gctgataagc
    21781 ctatacaagt tgctgtttct ttattttgag gttcagtaaa aatattttca ttatctatgt
    21841 cagttagctc tagtcttatt ttgtcttgat aatcctgatt tgtaactaca taaatattct
    21901 ccttcttaat taaaggaata attctttcta cagtattttc taaaaaactt ttgttgttta
    21961 taacttttaa aaactgcttc ggtttattcg ctcttgataa aggatataat cttgttccct
    22021 ttccgccagc taatataagc ccgtatatca cgaattttca actccatgta atactatact
    22081 taattatatg cactttatta tattttggtg aaatattagt tttatttatc ttaaatctat
    22141 attttcacga aattttttac ataaatttta caattgtaag ttaattatct tgttgacttt
    22201 tataatttgc agccatataa ttttattaaa caacatatat ttattaagag ggagtagtat
    22261 taaatatagc atcaacatac tcggcttaat cgcctggtgt tatataccta tttgggttac
    22321 gagactttta atatagtttt tattttataa aagctatatt aaaggtctct ttttttatac
    22381 aaactctaat agctatataa ttaataaaat ttagggggat atacatgaac aaattctttt
    22441 ccaagtcttc cgacgaaata ttaaaagact ttaatgttac taaagaaggt ttaaatgatt
    22501 ctcaagttaa taaaaatcta agtaaatatg gatacaatca actaactgaa aagaaaaaac
    22561 aaactgttct ggaagttttc ttaagccaat ttaaagattt acttgtatgc attttaattg
    22621 gagccgctat tatatctatg acaacaggta atattgaaag tacgcttgtt atttttgccg
    22681 ttattattct taatgccata cttggtacag ttcaacactt taaggctgaa caatctttag
    22741 atagtttaaa ggctttatca tcaccgtctg ctaaggtttt tagaaacggt cttaaaattg
    22801 aagttccatc taaaaatatt gttcctggcg atatactttt acttgaagct ggtgacttta
    22861 tagcagctga tggaagaatt atcgaaaatt tttctttaca agttaatgaa agttctttaa
    22921 ctggtgagtc tgaaagtgta aataaaacaa atgaaattat taatagtact gaactagctt
    22981 taggtgatca aaaaaatatg gtcttctctg gttctcttgt aacttatggt agagccttag
    23041 tagttgtaac aaatactggt atgaatacgg agataggtaa aattgcaaat ttaatggagc
    23101 aaactcaaga aaagaaaact cctcttcaag ttaatttaga tgattttagt aaaaaattag
    23161 cctttgctat tttagctgtt tgtattttag tctttggact tagtctttat agaggtactc
    23221 ctatgctaga ttctttgatg tttgctgttg cattagctgt agctgctatc cctgaagctc
    23281 taagttcaat tgttacaata gtacttgctc ttggaactca aaaaatggct aaagaaaatg
    23341 ctataataaa aaaattaaaa gctgttgaag ggttaggttg tgtctctatt atatgttcag
    23401 acaaaactgg tacattaact caaaataaaa tgactgtaaa aaaagtattt gttgataaca
    23461 agcttgttaa tggtactgat ttaaattgta ataactcagt agaaaattac ttattaaatt
    23521 gttctatcct ttgtaatgat tcaacttcaa aaaatggtaa agaaattggt gatccaacag
    23581 aagttgcact tgttaattta tctcataagt tttcattaga tgagctacta gtaagggatg
    23641 agtttaaaag attaagcgaa attccttttg actctgatag aaaattaatg agtactcttc
    23701 ataattttga taataaaaat ataatgttta ctaaaggtgc ttttgatgta ctattaaacc
    23761 gaattaaata tattaaaaca tctgatggtg ttagagagat aacgtatgaa gataaacaaa
    23821 acataataaa taccaataaa agcttatctg agaacggatt aagagttttg gcttttgcat
    23881 ataaagaatt aagttcaata aaagatttat cccttgaaga tgaacataac tatacattta
    23941 taggattaat ctcaatgata gatccaccaa gagaagaatc tgctaatgct gttgctgatt
    24001 gtataactgc tggtataaaa ccgattatga ttactggtga ccacaaaata acagcctctg
    24061 caatagctaa acaaatagga atattaagag atggtgatag agctattgaa ggtttagaat
    24121 tggataaaat gtctgatgaa gaccttaaac aaaatataga tcatatttct gtatatgcca
    24181 gagtttctcc tgaacacaaa attagaatag ttaaagcttg gcaagaaaaa gggcaaatag
    24241 ttgcaatgac aggtgatggt gtaaatgatg ctcctgcact taaacaagct gatataggta
    24301 tagcaatggg tataacaggt actgaagttt caaaagatgc tgcttcagta atattaacag
    24361 atgataactt tgcaactata gtaaaatctg tagctaatgg tagaaatatc tatagtaata
    24421 ttaaaaattc aattaagttc cttttatccg gtaatacttc tggtataatt gctgtattat
    24481 atgcttcctt aatggcttta ccaatgcctt ttgccgctgt acatttatta tttataaact
    24541 tattgactga tagcttacct gctatagcaa taggtatgga gaaatctcgt agggatcttc
    24601 taaaagatac tcctagaaaa aataatgact ctattctttc taaagacttt attttagaaa
    24661 taggttttga aggtttaata ataggtattt ttacaataat atcattttat ataggtttaa
    24721 aaactaataa tgccgttggc tcaactatgg cttttgctac a
//
