LOCUS       NZ_DS499662.1          24637 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_DS499662.1 Bacteroides stercoris ATCC 43183 Scfld_02_1, whole
            genome shotgun sequence.
ACCESSION   NZ_DS499662
VERSION     NZ_DS499662.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:44:33
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 213050
            Orig. end    :: 237687
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24637
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[223050:227687]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14637
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24637
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24637
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="2"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(78..515)
                     /locus_tag="ctg16_194"
                     /transl_table=11
                     /translation="MLKTILSISGKPGLYKLISQGKNMLIVESLVDKKRFPAYGNEKII
                     SLGDIAMYTDTEEVPLKDVLLSMKKKENGAAVALDVKKASVKELQAYLAAVLPNFDRDR
                     VYVSDIKKLISWYNLLVASDMTDFEETSETAAEEVKEETAE"
     CDS             complement(544..1158)
                     /locus_tag="ctg16_195"
                     /transl_table=11
                     /translation="MTVKIGITGGIGSGKSVVSRLLEVMGIPVYISDGETKQLMMTDSC
                     IRSELTALLGEEVYAGGVLNKSLLASYLFGSPEHAGQINGIVHPRVKEDFRQWVCQRAA
                     CRMAGIESAILIEAGFADEVDVVVMVYAPEEIRVQRAMKRDASSRELIEKRIRSQMGDE
                     EKRKLADFVIVNDGETPLIPQVLGLITFLSQNNTYLCPPKK"
     CDS             complement(1155..2165)
                     /locus_tag="ctg16_196"
                     /transl_table=11
                     /translation="MFDRRNIRRIYLNITGKTKDFLLSDKSREFFVFLFFFFIAGGFWL
                     LQTLNNDYEAEFSIPVRLRGVPNNTMITSEPVSELHIKVKDKGTVLLNYMLGKSFYPVS
                     LDFSDYKAVDNHVRIYASQFEKKVLSQLNVSTRLLSMKPDTLEYIYATGMSKLVPVRLS
                     GTVGAGRQYYLSDTIFKPDSVLAYAPEGVLDTITAAYTQPVKQENVSDTLRQQVSLLAR
                     RGVKFVPASIEMILPVDIYTEKTVEVPLHGVNFPADKVLRAFPSKVQVTFQVGLSRFRE
                     ITADDFHINVSYEELLRLGSDKYTVKLRNIPDGVKQVRFNPEQVDFLIEQISPSL"
     CDS             complement(2180..2509)
                     /locus_tag="ctg16_197"
                     /transl_table=11
                     /translation="MNLMTVFFLQAPAAGPDGSMMWIMLIAMFAIMYFFMIRPQNKKQK
                     EIANFRKSLQVNQKVITAGGIHGIIKEINDNDVVLEIASNVKIHIDKNSIFAAAADANS
                     SQASK"
     CDS             complement(2548..3510)
                     /locus_tag="ctg16_198"
                     /transl_table=11
                     /translation="LHLVKTPVFTLVMINRVLIRLKIIQIVYAYYQNGSKNLDAAEKEL
                     FFSLSKAYDLYNYLLMLMIALTNYAQKRIDAAKAKLAPTAEELYPNMKFVENKFISQLE
                     VNRQLMDFISNQKRTWENDEDFVKGLFEKIVASDIYKEYMASSENSYEADRELWRKLYK
                     TFIFNNEELDILLEDQSLYWNDDKEIVDTFVLKTIKRFDEKNGANQPLLPEFKDDEDQE
                     FARRLFRRAILNCDYYRHLISENTRNWDLDRVAFMDVVIMQCALAEILSFPNIPVSVSL
                     NEYVDIAKVYSTAKSGSFVNGTLDGIVKELKKEGKLSKN"
     CDS             3557..3682
                     /locus_tag="ctg16_199"
                     /transl_table=11
                     /translation="MQIIIIRAFSFDSLKKIVNFEPDYNKIAIIWKTLKRKADWT"
     CDS             3646..4047
                     /locus_tag="ctg16_200"
                     /transl_table=11
                     /translation="MEDFKKKSGLDVSDKEIVFSQSIKAGKRIYYLDVKKNRKDEMFLA
                     ITESKKIVTGEGDESQVSFEKHKIFLYKEDFEKFMNGLQQAIGFIQEQQGCFMRRNDNE
                     EQPDNVQPAEEQKEKDSPLDGEIKIDIDF"
     CDS             4186..4779
                     /locus_tag="ctg16_201"
                     /transl_table=11
                     /translation="MKSIEVKGTARTIAERSSEQARALKAIRKDNGVPCVLYGAGENVH
                     FTVPAEGLRNLVYTPHIYVVDLIIDGKKVNAILKDIQFHPVKDTILHVDFYQIDETKPI
                     VMEVPVQMEGLAEGVKAGGKLTLQMRKLKVKALYNAIPEKLIVNVSHLGLGKTVKVGEL
                     SYEGLELLNAKEAVVCAVKLTRAARGAAAAAANN"
     CDS             4922..5485
                     /locus_tag="ctg16_202"
                     /transl_table=11
                     /translation="MKYLIAGLGNIGPEYHETRHNIGFMVVDALAQAAGITFNDGRYGF
                     TATMSVKGRQLILLKPSTFMNLSGNAVRYWMQKENIPLENVLIVVDDLALPFGTLRLKG
                     KGSDAGHNGLKHIAATLGTQNYARLRFGIGNDFPRGGQVDFVLGHFTDEDWKTMDERLK
                     TAGEIIKSFCLAGIDITMNQFNKK"
     CDS             5482..5898
                     /locus_tag="ctg16_203"
                     /transl_table=11
                     /translation="MSEARIDKWMWAVRIFKTRTIAAEACKKGRISINGALAKAARMVK
                     PGDVIQVRKPPVTYSFKVLQTIEKRVGAKLVPEMMENITAPEQYELLEMSKISGFINRA
                     KGTGRPTKKDRRELEDFTAPEFVDDFDFDFDFEE"
     CDS             5908..6894
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_204"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 8.8e-26, bitscore:
                     85.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C (E-value: 7e-07, bitscore:
                     23.3, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKIIKWGFIGCGEVTKYKSGPAFQKIEHSEVVAVMSRDISKAK
                     AYAKERGIAKWYNDAQELINDEDVNAVYIATPPSSHATYAIMSMKAGKPVYIEKPMAVT
                     YEECCRINRISQETGIPCFVAYYRRYLPYFLKVKSLVEEGAIGNVINIQIRFAQPPRDL
                     DYNKENLPWRVQPDIAGGGYFYDLAPHQIDILQDMFGYILEANGYKSNRGGLYSAEDTL
                     SACFQFDSGLVGSGSWCFVAHESAREDRIEIIGDKGMICFSVFTYDPIALHTERGREEI
                     PVENPIYVQQPLIQAVVDHLLGKSICNCDGESATLTNWVMDKILNKI"
     CDS             complement(7000..7425)
                     /locus_tag="ctg16_205"
                     /transl_table=11
                     /translation="MKSDPKDCLYCQNNETLHNLMIEIAQLSVSRVFLFKEQTYRGRCL
                     VAYKDHVNDLNELTDEERNAFMADVARVTRAMQKAFNPEKINYGAYSDKLSHLHFHLAP
                     KYVDGPDYGGTFQMNPGKVYLTDVEYQELVEAVRSKL"
     CDS             complement(7482..9749)
                     /locus_tag="ctg16_206"
                     /transl_table=11
                     /translation="MSHLAPLIADLALILICAGIMTLLFKKLKQPLVLGYVVAGFLASP
                     HMAYTPSVMDTANIQTWADIGVIFLLFALGLEFSFKKIVKVGGAAIIAACTIIFCMILL
                     GVAVGTAFGWKRMDCIFLGGMIAMSSTTIIYKAFDDLGMRKKKFTGLVLSVLILEDILA
                     IVLMVMLSTMAVSHNFEGTEMLGSIAKLLFFLILWFVVGIYLIPVLLKKCRKLMSEETL
                     LIVSLGLCFGMVVLAAHTGFSAAFGAFIMGSILAETVEAESIERLVKPVKDLFGAIFFV
                     SVGMMVDPLMIVEYAGPIVVITLAVIVGQSLFGTLGVLLAGQPLKTAMQCGFSLTQIGE
                     FAFIIASLGVSLHVTSHFLYPIVVAVSVITTFLTPYMIRFAEPASNFVDTHLPERWQKF
                     LLHYASGSQTVNHESLWKKLIFALLRITVVYSIVSVAVIAIAFRFLVPFFKGNLPGIWG
                     SLLSALVIVLFISPFLRAIMIKKNHSVEFVTLWRDSRGNRAPLVATIVLRILLAVSFVM
                     FVIAGLFKLSVGLVFGVAVLLVIVMILSRQLKRQSIMIERTFFQNLRSRDMRAEYLGEK
                     KPEYAGRLLSRDLHLTDYEIPGESAWAGKTLAELNFGKRYGVHVVSILRGRRRINIPGA
                     SVRLFPLDKIQVIATDEELNVFGEEMNKLSTIAADAVEKSEMILRQLRIDANSPFLGKT
                     LKDAGIREKYHCLIVGVERGGETLHAPDVHEPFVEEDVVWIVGENVDVYKLVGENDENV
                     DL"
     CDS             10001..10417
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_207"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.7e-24, bitscore:
                     80.3, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDVKIELLEPTSPESTIAKFIEKNNGNGGMHHLAFAVEDGVANALAEVEGKGIRL
                     IDKAPRKGAEGLNIAFLHPKSTLGVLTELCEKGE"
     CDS             10485..12038
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_208"
                     /sec_met_domain="CT_Btheta (E-value: 1.2e-290, bitscore:
                     958.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRTAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIDGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAKTEEEGLALIRKLLSYIPQNNLEEAPYTDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIVDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             12086..13018
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_209"
                     /sec_met_domain="OAD_gamma (E-value: 3.1e-14, bitscore:
                     47.4, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLMLVLGFCSSCGEKESNSKLLLNEVLITNESNFQ
                     DDYGVHSAWIEIFNKSYGSADLAGCYLKFSSQPGDTATYFIPKGDVLTLVKPRQHALFW
                     ADGEPNRGTFHTNFKLDSQNANWIGLYDSGKKLLDQIVVPAGTLQANQSYARVSDATPE
                     WEVKGDASDKYVTPSTNNKTIDSNAKMEKFEEHDSIGIGMAISAMSVVFSGLLLLYISF
                     KIIGKISVNLSKRNAMRAKGITDKKEAKEKQLGEAPGEVFAAISLALHEMQSDVHDVED
                     TVLTITRVKRSYSPWSSKIYTLRETPQRK"
     CDS             13044..13475
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65; E-value:
                     1.4e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_210"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.9e-20, bitscore:
                     65.0, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNAYKVTIGDIEDNIAHVEVNGTPYKVEMEKAPKVA
                     VKPVVRPVSAAPAAPTAPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVIII
                     LEAMKMENNINADKDGKITAINVSKGESVLEGTDLVIIE"
     CDS             13477..14637
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_211"
                     /sec_met_domain="OAD_beta (E-value: 2.4e-152, bitscore:
                     500.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATGGHLVMILVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMTALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTSKNERLIRMKPPRAVSHTEKVMFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTTDSLWIFGLGAFSFIIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             14746..16596
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_212"
                     /sec_met_domain="Alpha-amylase (E-value: 3.3e-61, bitscore:
                     201.7, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVFFILGTLLLSLSTYAAMNVNKIDPPFWYTGMQNPELQLMVY
                     GEGIGNATVSVNYPGVSLNSTVKLESNNYLLVYLRLDKNVKPGKMPLTFTQGKKKFVKE
                     YELKERAKKGCEHKGFDASDALYLLMPDRFANGNPDNDQIAGMAEYKVDRNDPNARHGG
                     DLAGIEQHLDYFSDLGVTALWFTPVLENNMTGGSYHGYATTDYYKVDPRFGTNEEYKQL
                     IEKSHTRGIKIVMDMIFNHCGVEHIWIKDMPCKDWFNNPDHENNFVQTSFKLTPHVDPY
                     ASKYDFSQMNDGWFVTAMPDLNQKNPHVYRYLVQNSFWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPKNSNLKTVMDFSFYDKI
                     NIAKTEETETWFKGLDRVYNSFVYDFLYPNPESVLAFIENHDTDRFLGEGENLPMLKQA
                     STLLLTTRRIPQLYYGTEIMMNGIKSKSDGYVRKDFPGGWADDKETALTAEGRSKIQND
                     CYNFYKTILNWRKGNDVIAKGSMTQFMVQNGVYAYARQYEGKIVFVMLNGTDSETTVPL
                     KFYKEILKDKKQGKDILSGKTILFEKELKMEARESLIIEL"
     CDS             complement(16727..17737)
                     /locus_tag="ctg16_213"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFARAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVDYAHQFDVTVEGELGVLAGVEDEVSAEHHT
                     YTNPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQCHVDPATGRLVPPPLEFAVLDAV
                     MEKLPGFPIVLHGSSSVPQEEVDTINQFGGKLEAAIGIPEEQLRKAAKSAVCKINIDSD
                     SRLAMTAAVRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIVNVLGSENKLAQLD"
     CDS             complement(18067..19230)
                     /locus_tag="ctg16_214"
                     /transl_table=11
                     /translation="MFQDKYVFSQLTAFLNRTQFNNYVRKYDGNRYVKHFTCWNQMLAM
                     MFGQLSNRESLRDLVVAFEAHRAKQYHLGLGREPIAKTTLATANQNRDYRIFEDFAFYM
                     MKEACEKRTTNILDISGKKYAFDSTTIPLCLATFPWAKFRSKKGGVKAHVLYDIEAQVP
                     AFYTVTTASKHDSTAMSSIHYEPNAYYIFDRAYDSFKELYRIHLTDSFFVVRAKTNLKY
                     KTVRWKRRMPKNIMTDAEVKLTGYLSEKKYPESFRLVRYYDEEDDREFTFLTNAKQLSA
                     LDVADLYKKRWLIELFFKWLKQHLKIKKFWGTTENAVRIQISVAIITYCLVAIVQHDMK
                     LKRSTYEVLQILSISLTDKTHLRDLFDKTNFNDVKDLNDPLIPGLFD"
     CDS             complement(19330..20451)
                     /locus_tag="ctg16_215"
                     /transl_table=11
                     /translation="MKKGFLQKKLAIDRFITFYFRFLQEINIISPMRKLIVFFSFWFSA
                     TIVVAQNTERKLYSIAFYNLENLFDTIHDAGKNDYDFLPDGSYRWTAKKYEAKLHNLSD
                     VLSALSRNLVPEGPAVIGVAEVENHRVLTDLVSQPAMANYKFVHYEGPDRRGIDCALLY
                     DPQQFAVTNSKLVLSAPFEGDTVHLTRGFLIVDGRMAGERVCFIVNHWPSRGAKSPVRV
                     HAARQVKALTDSLMHEDKKLKLFVMGDMNDDPMDESMQTLGARKYISGMKANQFFNPWW
                     EILEDKGVGTLLYRGKWNLFDQIVLSRPLVKAKKGLRYDHSEVFIRDYLIQQDGKYKGS
                     PLRTHGGRVWLNGYSDHLPTIIYLKTLLSRKSG"
     CDS             20549..20800
                     /locus_tag="ctg16_216"
                     /transl_table=11
                     /translation="MKKGIHPENYRPVVFKDMSNGDVFLSRSTVNTKETIEFEGETYPL
                     VKLEISSTSHPFYTGKSKLVDTAGRVDKFMSRYGNRKK"
     CDS             complement(20931..22022)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GCV_T"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GCV_T_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_217"
                     /sec_met_domain="GCV_T (E-value: 6e-96, bitscore: 314.7,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 2.5e-23, bitscore: 75.9,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTTPFTETHISLGAKMHEFAGYNMPIEYSGIIDEHLTVCQGVGV
                     FDVSHMGEFWVKGPHALDFLQTVTSNNVAALTPGKVQYTCFPNEDGGIVDDLLVYRYEQ
                     EKYLLVVNASNIEKDWNWCMSHNTMGAELENASDRMAQLAVQGPKAIEALQKLTPVNLS
                     ELSYYTFTHGEFAGEPDVIISNTGYTGAGGFELYFYPEAAIKIWNAVFEAGAEFGIKPI
                     GLGARDTLRLEMGFCLYGNDLDDTTSPIEAGLGWITKFVEGKNFINRPMLEKQKTEGTV
                     RKLVGFEMVDRGIPRHGYELQNPEGTPIGVVTSGTMSPTRKIGIGMGYVKPEYSKVGTE
                     ICIDMRGRKLKAVVVRPPFRGKV"
     CDS             complement(22052..23278)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_218"
                     /sec_met_domain="Peptidase_M20 (E-value: 2.6e-14, bitscore:
                     47.4, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVERFLKYVSFDTQSNEESGVTPSTPGQMVFARFLKEELEALG
                     LEEITLDENGYLFATLPANIDKSVPVVGFIAHMDTSPDMSGKDVSPRIVENYDGKDIVL
                     CADEQVVLSPARFPELLDHKGEDLIVTNGKTLLGADDKAGIAEIVSAVAYLKEHPEIKH
                     GKIRIGFNPDEEIGLGAHKFNVEQFGCEWAYTMDGGEVGELEFENFNAASAKIVFKGRN
                     VHPGYAKNKMINSIRVANRFISMLPSHETPEHTEGYEGFYHLIGITGEVEQTTVTYIIR
                     DHDRVRFESRKKEFEHLVCKINAEYGEGTAALELHDQYYNMREKIEPVMHIIDTAFKAM
                     EAVGVEPHVKAIRGGTDGAQLSFKGLPCPNIFAGGLNFHGRYEFIPIQNMEKAMNVIVK
                     IAELVAANK"
ORIGIN
        1 ctaaaaagaa acaattagca agcggatgtt aattttgaca taccctcttt ttattttaac
       61 ctcagaatga agtataatta ttcagctgtt tcttctttaa cctcttcagc agcagtttca
      121 gatgtttctt caaagtctgt catatcactt gctaccaaca gattatacca ggaaatcagt
      181 tttttaatat cagacacata tacgcggtcg cggtcaaaat taggcaacac cgccgccaaa
      241 taagcttgga gctctttcac agaagccttt tttacatcca atgccacggc tgcaccgttt
      301 tcctttttct tcatagagag aagtacatct ttcaaaggta cttcttctgt atctgtatac
      361 atggcaatat ctcctaaaga gataatcttt tcattaccat aagcaggaaa acgtttcttg
      421 tcaacaagtg actccacaat caacatattc tttccctgag agatgagttt atacaatccc
      481 ggcttaccgg aaatagacaa aatagtcttc aacataatat attcagtttt tgtaattagt
      541 agttcatttt ttcggtgggc aaagataggt attattttga gacagaaaag tgattaagcc
      601 caaaacctgc ggaattaacg gtgtttcgcc atcattcact atcacaaaat ctgccagttt
      661 ccgtttttct tcatcgccca tctgactacg aatgcgcttt tctatcagtt cacgtgagga
      721 agcatcccgc ttcatggcac gctgcacccg tatctcctcg ggagcgtaga ccataacaac
      781 tacatcaacc tcatctgcaa atccagcctc tatcagaata gcagactcga ttcctgccat
      841 ccggcatgcc gcacgctgac aaacccactg cctgaaatcc tcttttacac gcggatgaac
      901 aataccatta atctgcccgg catgctcggg actaccgaaa agataagacg caagcagaga
      961 cttattcaat actccaccgg catacacctc ctcacccaac aaggcagtca actcactgcg
     1021 aatacaagag tctgtcatca taagctgttt ggtttcccca tcagaaatat agaccgggat
     1081 tcccatcacc tccaacagtc gggacacaac actttttcca ctgccgatac caccggttat
     1141 acctatcttg acagtcataa tgaaggagat atttgttcta taagaaaatc aacctgctcc
     1201 ggattaaaac gcacttgttt caccccgtcg ggaatattcc gcaattttac cgtatacttg
     1261 tccgagccca aacgcagcaa ttcctcataa gaaacattga tatgaaaatc atctgcagtt
     1321 atctcacgga aacggctaag ccctacctgg aaagttactt gaaccttaga aggaaaagca
     1381 cgcaatactt tatcagccgg aaagtttacg ccgtgcaacg gtacttccac cgtcttttcc
     1441 gtataaatgt ccacaggaag tatcatctcg atagaggcag gaacaaactt cacacctcgt
     1501 cgcgcaagca aagacacctg ttgccgcaat gtatcggaga cattctcctg tttgacaggc
     1561 tgggtatagg cagcggttat cgtatccaat accccttccg gtgcataagc caaaaccgag
     1621 tccggtttaa aaatcgtatc cgacaaataa tattgacggc cggcacccac tgtccccgat
     1681 aatctgacag gtaccaattt ggacattccc gttgcataaa tgtattccaa ggtatctggc
     1741 ttcatagaaa gcaagcgggt ggaaacattc aactgactca gcactttttt ctcaaactga
     1801 gaagcataaa tacgtacatg attatcaaca gctttataat cggaaaagtc aagcgaaacc
     1861 ggatagaagc tctttcccaa catataatta agcaaaacag tacctttatc ctttaccttt
     1921 atatgcagtt cggagaccgg ctctgaagta atcatcgtat tattaggcac tccacgcaaa
     1981 cggaccggaa tagaaaattc cgcttcataa tcgttgttca gtgtctgcaa caaccagaaa
     2041 ccaccggcta taaagaagaa aaataaaaaa acaaagaact ctctgctctt atcactgagc
     2101 agaaagtcct ttgtttttcc ggttatattc aaataaatac gtcttatgtt cctacgatca
     2161 aacataggct cacatctgct tatttagaag cctgactact gtttgcatca gcagcagcgg
     2221 caaaaatgga attcttgtca atatggattt taacgttgga agcaatttca agaaccacat
     2281 cattatcgtt aatttccttg ataataccat gaatgccacc ggcagtaatc accttttggt
     2341 tcacttgaag agatttgcgg aaattcgcaa tttctttttg cttcttattt tgcgggcgaa
     2401 tcataaagaa atacataata gcgaacatag ctatcaacat aatccacatc atgcttccgt
     2461 ccgggcctgc agcaggagct tgcaggaaaa atactgtcat caaattcata aatattccgt
     2521 tttaattttt attattcaac aaaggtatca gtttttcgac aacttccctt cttttttcaa
     2581 ttccttaact attccatcca aagtgccatt gacaaaactg ccactcttgg ctgtactgta
     2641 cactttggct atatctacat actcattcaa cgaaacgctg acgggaatgt tcgggaaact
     2701 caatatttcg gccaatgcac actgcatgat aactacatcc ataaaagcta cacggtccaa
     2761 atcccagtta cgtgtgtttt cgctaataag atgacggtag taatcgcagt tcagaatagc
     2821 acggcggaac aaacggcggg caaactcctg atcttcatca tccttaaact caggcaataa
     2881 cggctgattc gcgccattct tctcatcaaa gcgtttgatt gttttcagaa cgaatgtatc
     2941 cacaatttcc ttgtcgtcat tccaataaag gctttgatct tcgagtaata tatcaagttc
     3001 ctcattattg aaaatgaatg tcttataaag ctttctccat aattcacgat ctgcctcgta
     3061 agagttttcg gaagaagcca tatattcctt atatatatca gacgctacaa tcttttcaaa
     3121 taacccttta acaaaatctt catcattctc ccaagtacgt ttctggttgg aaataaagtc
     3181 catcaactgc ctgttcactt ccagttggga aatgaatttg ttttctacaa acttcatgtt
     3241 cggatacaac tcttcggctg tgggagccaa ctttgctttt gccgcatcaa tgcgcttttg
     3301 tgcgtagttc gtcaaggcta tcatcaacat aagcagataa ttgtaaaggt catatgcctt
     3361 ggagagacta aagaacaact ctttctccgc agcatctaaa tttttactgc cattctgata
     3421 ataagcatat acaatctgta taatcttaag acgaataaga actctgttta tcataactaa
     3481 agtaaatact ggtgttttaa cgaggtgcaa aagtagatat ttttaatgag tttacataaa
     3541 taaatcacat tttttaatgc agataatcat tatccgggct ttttcttttg acagtttaaa
     3601 aaaaatcgtc aattttgaac ccgattacaa caagatagct ataatatgga agactttaaa
     3661 aagaaaagcg gactggacgt gagcgacaaa gaaatagtat tctcccaatc cattaaagca
     3721 ggcaagcgca tctattattt agatgttaag aaaaacagaa aggacgaaat gttccttgct
     3781 atcactgaaa gcaagaagat agtaacgggt gaaggagatg aatcacaggt tagttttgaa
     3841 aaacataaaa tctttttgta caaagaagat tttgaaaaat tcatgaatgg cctgcaacag
     3901 gctattggct tcattcagga acagcaagga tgttttatgc gccgcaacga caatgaagaa
     3961 caacctgaca atgtgcagcc ggcagaagaa cagaaagaaa aagattctcc gcttgacgga
     4021 gaaattaaaa tagatattga tttttaaagg aaaacctttt gataattcaa aaagaagcgg
     4081 tatttttgca ccgctttttt gcaacatcgt gtggtgaacc acatcgtgtg atggtgaatt
     4141 aagcaataat ctacttaatt tagagtaaca caaaaagaaa ttaaaatgaa atcaattgaa
     4201 gtaaaaggaa ctgcaagaac tattgcagag cgttcttcgg aacaagcaag agctttgaaa
     4261 gctattcgta aagacaacgg tgtaccttgc gtactctacg gggcaggtga aaacgtccat
     4321 ttcactgtac cggcagaagg tctgcgcaat ttggtttata ctccgcacat ctacgtggtt
     4381 gacctgatta tcgatggcaa gaaagtaaat gctatcttga aagatattca attccacccg
     4441 gtaaaagata ctatcctgca cgttgacttc tatcagattg atgaaactaa acctatcgta
     4501 atggaagttc ccgtacaaat ggaaggtctg gcagaaggtg tgaaagccgg tggtaagctg
     4561 actctgcaga tgcgtaaact gaaagttaaa gctttgtaca acgctattcc tgaaaaactg
     4621 attgtcaatg tatctcattt gggattgggc aaaacggtaa aagtaggtga attaagctac
     4681 gaaggtttgg aactgttgaa tgctaaagaa gccgttgtat gtgctgttaa gctgactcgt
     4741 gccgcaagag gtgctgctgc agctgctgca aacaactaat cggcgctttc ttagtaagca
     4801 aacgagatat tccggaacgc ggattaacgc agacgacgca gatttcatat ccgcggacaa
     4861 ctgcgataat ccgcgttcct ctctttttat ctgaattatc attaaagcca agtatataaa
     4921 aatgaaatat ctaattgccg gtttaggcaa tatcggtccc gaatatcacg aaacccgcca
     4981 taatataggc ttcatggtag tagatgcttt agctcaagca gccggaataa cctttaatga
     5041 cggacgctat ggttttacag ctaccatgtc ggtcaaagga cgccaactga tattgctgaa
     5101 accgtctact ttcatgaatc tgagtggaaa tgccgtacgc tattggatgc aaaaagagaa
     5161 cattccgttg gaaaacgtac tgattgtagt agatgatttg gcactacctt tcggcaccct
     5221 gcggctgaaa gggaaaggaa gcgatgcggg acataacgga ctgaaacata ttgcagccac
     5281 attaggtacc caaaactatg cccgcctgcg ttttggtatc ggtaatgatt ttccccgcgg
     5341 cggacaagtg gatttcgttt tgggacactt tacggacgaa gactggaaaa caatggatga
     5401 acgcctgaaa acagcaggcg aaatcattaa aagtttctgt ctcgccggta tagacattac
     5461 aatgaatcag ttcaacaaga aatgagtgaa gcaagaatag acaaatggat gtgggctgta
     5521 cgcatattca agacacgtac aattgcagcc gaagcctgca aaaaaggacg tatcagtatc
     5581 aatggtgcac ttgcaaaggc agctcgaatg gtgaagccgg gagatgtaat acaagtacgc
     5641 aaaccgccgg ttacctattc tttcaaagta ctacagacta ttgaaaagcg tgtaggcgcc
     5701 aagcttgttc ccgaaatgat ggagaacata accgccccag agcaatatga actgttggaa
     5761 atgagcaaaa tcagcggatt tatcaaccgc gctaagggaa cgggacgccc caccaaaaag
     5821 gatcgccgtg aactggaaga cttcactgcg cctgaattcg tggatgactt tgattttgat
     5881 ttcgactttg aagaataata tacaagtatg agtgagaaaa taataaaatg gggatttatc
     5941 ggctgcggag aagtgaccaa atacaaaagt ggacctgcat ttcagaaaat tgaacactcc
     6001 gaagtggtag ctgtgatgag tcgggatatc tccaaagcca aagcttatgc caaagaaaga
     6061 ggcattgcca aatggtacaa tgatgcacag gaactgatta atgatgaaga cgtaaatgcc
     6121 gtatatattg ccaccccacc ctcttcccat gccacatatg ccattatgtc catgaaagcc
     6181 ggcaaaccgg tatacataga aaagccgatg gcagtgactt atgaagagtg ttgccgtatc
     6241 aaccgtattt cccaagaaac cggcatacct tgttttgtag cctattaccg ccgttatctt
     6301 ccttatttcc tgaaagtaaa gtcattggtg gaagaagggg ccatcggaaa tgtcatcaat
     6361 atacaaattc gctttgccca gccaccccgc gatctggact ataacaagga gaacctaccc
     6421 tggcgtgtac agcccgatat cgccggtggc ggttattttt atgatttggc tccacaccag
     6481 atagacatac tgcaagatat gttcggatat attcttgaag ccaacggata caagagcaac
     6541 cgtggcggac tatattctgc agaggatacc ctcagtgcct gtttccaatt tgacagcggc
     6601 ctggtaggca gcggctcgtg gtgtttcgtt gcacatgagt ctgcacgtga agaccgtatc
     6661 gaaatcatcg gagacaaagg tatgatatgc ttttctgtat ttacctatga tcccatagcc
     6721 ttacacaccg aacgaggaag ggaagaaatc cctgtagaaa accccattta cgtccagcaa
     6781 ccgcttattc aagctgttgt agaccattta cttggcaaat caatctgtaa ctgcgatggc
     6841 gaaagcgcaa cactgacaaa ctgggtaatg gacaaaattt taaataaaat ataaaatacg
     6901 aagtataagg tataaatggc tatgctatga tattacataa ccatttgtca ttcataaatc
     6961 atgctcattg ccaatttata ctttatactt cattctcttt caaagtttgc ttctcaccgc
     7021 ttcaaccaat tcctgatatt cgacatccgt cagatacacc tttcccggat tcatctggaa
     7081 agtaccacca taatcgggac catctacata tttcggcgcc aaatgaaaat gaagatgaga
     7141 taatttgtct gaatacgcac cataattaat cttttccgga ttaaaagctt tttgcatggc
     7201 acgagtcaca cgggcaacat cagccataaa agcattgcgt tcctcatccg ttagttcatt
     7261 caagtcattg acatggtctt tgtaagccac aaggcagcgc ccgcgataag tttgttcctt
     7321 aaaaaggaag acacgtgaca cactaagctg cgcaatctca atcatcagat tatgcaacgt
     7381 ttcattattc tgacagtaca gacagtcttt cggatcactt ttcatgatat ttctttttta
     7441 aagtttatgt tcgtaaagca aagataaccg ttattccaat atcacaggtc gacattctca
     7501 tcattttcac cgaccaattt gtacacatcg acattctcac cgacaatcca tactacatcc
     7561 tcctcgacaa aaggctcgtg cacgtcagga gcatgcaaag tttcccctcc tcgctccact
     7621 ccaacaatca ggcagtggta tttctcgcgt atgcctgcat ctttcaatgt tttacccaag
     7681 aacggagaat ttgcatcgat acgcaactga cgcagtatca tctcactttt ttccacggcg
     7741 tccgcagcta tcgttgaaag cttattcatt tcctcaccaa acacattcaa ttcttcatca
     7801 gtagcaataa cctgtatctt atctaaagga aagagacgca cagaagcacc gggaatattt
     7861 atccgcctgc gtccacgaag aatagaaacg acatgcaccc cataacgctt gccaaaattc
     7921 aactccgcca gcgtcttgcc tgcccaagcc gattccccgg gaatctcata atccgtcaaa
     7981 tgcaaatcac gcgaaagcag acggcctgca tattcaggct tcttctcgcc caaatattcc
     8041 gcacgcatat cccgcgaccg caaattctga aaaaaagtac gttcaatcat tatagactgc
     8101 cgcttcaact gtctggaaag tatcattact ataaccagca gtaccgcaac tccaaagaca
     8161 agaccaaccg acagtttaaa caatccggct attacaaaca tcacaaaaga aactgccaac
     8221 agaattcgca gcacgatagt agctaccagt ggagcgcgat ttccccgact gtcgcgccac
     8281 aatgttacga attctaccga atggtttttc ttaatcatga tggctcgcag aaaaggagaa
     8341 ataaacagaa caatgaccaa agcagacaat aaagagcccc aaattccagg caagtttccc
     8401 ttgaaaaacg gtacaaggaa gcggaatgcg atagcaatca ccgccacact tacaatggaa
     8461 taaaccaccg taatacgcaa caaagcaaat atcagtttct tccataaact ctcatgattc
     8521 acagtctgcg aaccggaagc ataatgcagc aaaaatttct gccaccgttc cggcaaatgc
     8581 gtatcgacaa aattggaagc cggttctgca aaacgaatca tataaggggt aagaaaggta
     8641 gtaatgacag atacagccac cactatagga tacagaaaat gacttgttac atgcaaagac
     8701 actcccaaag aagcgatgat aaaagcaaat tctccaatct gcgtcaaact gaatccgcat
     8761 tgcatagccg tcttaagcgg ctgccctgca agcaatactc ccaatgtgcc gaacaacgat
     8821 tgcccgacaa taaccgccaa tgtaatgaca acaataggac ccgcatattc tactatcatc
     8881 aaagggtcta ccatcatacc tacagataca aagaatatgg caccgaataa atcttttacc
     8941 ggcttaacca gacgttcaat actttccgcc tctaccgttt cagccagaat agaccccatg
     9001 ataaaagcgc cgaacgctgc tgaaaatccc gtatgggcag caagcacaac cataccgaaa
     9061 caaagcccga gcgatacaat cagcaaagtc tcctcactca tcagcttccg acattttttc
     9121 aacagaacag gaatcaaata gatgccgacc acaaaccaca atataagaaa gaataacagt
     9181 tttgctatac tgcccagcat ttccgtccct tcaaaattat gactgactgc catggtagac
     9241 agcataacca tcaggacaat ggcaagaata tcttccaaaa tcaacacact gagcaccagc
     9301 ccggtaaact tcttcttgcg catgcccaaa tcatcaaatg ccttatagat aatagtagtg
     9361 gaagacatgg ctatcatacc gcccaagaaa atgcaatcca tccgtttcca tccgaaagcc
     9421 gtgccaactg ccacgcccaa caatatcata cagaatataa ttgtacaagc agcgattata
     9481 gcggctcccc ccaccttgac tattttctta aagctaaact ccagccccaa agcaaacagc
     9541 aagaaaataa cgccgatgtc cgcccaagtc tgtatgtttg ccgtatccat caccgaaggg
     9601 gtataagcca tgtgaggact ggccaagaag cctgcaacga cataccccaa gactaacggt
     9661 tgtttcagtt ttttaaataa tagcgtcatt attccggcgc aaatcagtat caatgccaaa
     9721 tcggcgatca aaggagctaa atgtgacata atatttgtcc gattgaaatt ctactgacaa
     9781 agatataaca aaaaaagctt ttgaatctct tttataacaa aaaacgagta ccatcaatag
     9841 ataaaacaac gaccggttgt ctcaattata aaatcatttt aagaagaaat acctttataa
     9901 ttaattggcg aaaaatttct ttattcaagt agaaatatct ttctttgtac tgctgatttt
     9961 aaaaatttgg aattgaatac caacattaat aaaaactgtt atgaaaattt cgcacattga
    10021 acatttaggc attgctgtaa aaagcattga agaagcactt ccgtactacg aaaatgtatt
    10081 aggtttaaaa tgctacaaca ttgaaaccgt agaagatcaa aaggtaagaa ccgctttctt
    10141 gaaagtaggt gacgtgaaaa ttgagttgct cgaacccact tctcccgaaa gcaccattgc
    10201 caaattcatc gaaaagaaca acggtaacgg cggtatgcac catttagcat ttgctgtgga
    10261 agacggagtg gcaaacgctc tcgcagaagt tgaaggaaaa ggtatccgcc tgattgacaa
    10321 agctccccgt aaaggtgcgg aaggcttgaa catcgcattc ctgcatccga aatccacact
    10381 cggcgtattg acggaacttt gcgaaaaagg agaataaaga tttatggttt gaaatcataa
    10441 atccgaaaac ataaatctga aatcataaat cataaataaa gaatatgagt aatcaacttg
    10501 agaaaattaa agagcttatt gaccgccgta cggctgcgcg tcttggtggt ggtgaaaaag
    10561 cgattgcaaa gcaacatgag aaagggaaat atacagctcg cgagcgtata gcaatgttac
    10621 tcgatgaagg aagtttcgaa gaaatggaca tgtttgttga gcacagatgt acgaatttcg
    10681 gtatggaaaa gaaacactac cccggcgacg gtgtggttac cggttgcggt accatcgacg
    10741 gtcgcttggt ctacattttc gcacaggatt tcactgtttc tgccggttca ttgtcggaaa
    10801 ccatgtcttt gaagatttgc aaaatcatgg atcaagcaat gaagatgggt gctccctgca
    10861 tcggtatcaa tgactcgggt ggtgcacgta ttcaagaagg tatcaatgct ttagccggat
    10921 atgccgagat tttccaacgc aatattcttg cttccggcgt tattccccaa atttccggta
    10981 tcttcggtcc ttgtgccggt ggtgcggttt attctcctgc cctgactgac tttacactaa
    11041 tgatggaagg aacgtcctac atgttcctta ctggtccgaa agtggtaaag accgtaaccg
    11101 gagaagatgt cagccaggaa aatttgggtg gtgcaagcgt acactctacc aaatccggtg
    11161 taactcactt cactgcaaag accgaagagg aaggtcttgc acttatccgc aaattactga
    11221 gctacatccc tcaaaataat ttggaagaag ctccttacac agattgtaca gatcccatcg
    11281 accgtctgga agattctctg aacgatatta tccctgacaa tccgaacaag ccttacgata
    11341 tgtacgaagt tatcggtgct atcgttgaca acggagagtt ccttgaaatt cagaaagact
    11401 attccaagaa tatcattatc ggttttgccc gtttcaacgg acaatcagtc ggcattgtag
    11461 ccaaccagcc caaatatctg gcaggtgtac ttgatagcaa cgcttctcgt aagggtgcac
    11521 gtttcgtccg tttctgcgat gctttcaata ttcctatcgt atctttggta gatgtaccgg
    11581 gcttccttcc cggaaccggt caggagtaca acggtgttat cctgcacggt gccaaattgc
    11641 tgtatgccta cggtgaagct accgtaccta aagttactat caccctacgc aaatcctatg
    11701 gcggttcgca catcgtaatg agctgtaagc aacttcgtgg tgacatgaac tatgcatggc
    11761 ctactgctga aatcgcagtt atgggtggtg caggtgcggt agaagttctg tatgcacgcg
    11821 aggctaaaga gcaagaaaat ccggctcagt tcctggctga aaaagaagct gaatatacca
    11881 aactgtttgc caatccttac aatgcagcca agtatggcta tatcgatgat gttatcgaac
    11941 cgcgcaacac gcgtttccgc attatccgcg ccctgcaaca actgcaaacc aagaaattga
    12001 ccaacccggc caagaaacat ggtaatattc ctctttaaga attgagaatt aacagttgag
    12061 aattaaaaaa taaaaactca aatttatgaa taaaacaaaa atcggaatat tcctttcatt
    12121 gatgctggtg ctggggttct gttcttcttg tggagaaaag gagtcaaact ctaaactgtt
    12181 gctgaatgaa gtgcttatca ccaacgaaag caactttcag gatgattacg gtgttcacag
    12241 cgcatggatt gagatattca acaaatcata tggcagcgcc gaccttgcag gttgctatct
    12301 gaaattcagc agccaaccgg gtgacaccgc tacctatttc atcccgaaag gtgatgtcct
    12361 gactttggta aaacctcgtc agcacgcgct gttttgggca gacggagaac ctaatcgcgg
    12421 tactttccat accaacttta agttagacag ccagaacgcc aattggatcg gcttatacga
    12481 ttccggcaag aaattactgg accagattgt ggtacccgcc ggaacattac aagccaacca
    12541 atcttatgca cgtgtcagtg atgccactcc ggaatgggaa gtaaaaggag atgcgtccga
    12601 taagtatgta actccaagca ccaataacaa aaccattgac agcaatgcta aaatggagaa
    12661 gtttgaagag catgacagta taggtatcgg tatggctatt tccgccatga gtgtagtatt
    12721 ttccggatta ctccttcttt atatctcttt caagattata ggcaagattt ctgtaaacct
    12781 cagcaaacgt aacgcaatgc gcgctaaggg cattaccgat aaaaaagagg ctaaagaaaa
    12841 acaactggga gaagcaccgg gtgaagtatt cgcagccatt tccctggcat tgcacgaaat
    12901 gcagagtgat gtacacgatg tggaagacac cgtactcacc attacccgcg taaaacgcag
    12961 ctattcacct tggagttcaa agatttacac gttgcgtgaa acccctcaga gaaagtaaag
    13021 tcacctttaa taaagataaa acgatgaaag aatataaata caaaatcaac ggtaacgcat
    13081 ataaagttac tattggagat attgaagaca acatcgctca cgtagaagtg aacggtactc
    13141 cctacaaagt agaaatggaa aaagctccga aagttgcagt caaaccggta gtacgccctg
    13201 ttagtgcagc cccagctgcc ccgactgctc cagttgtaaa accggctgct gcttcaaccg
    13261 gcaagtcagg tgtaaaatct ccgctgccag gtgttatcct tgacatcaaa gtcaatgtgg
    13321 gtgataccgt gaagaaaggc caggttatca ttatcctgga ggccatgaaa atggagaaca
    13381 atatcaatgc cgacaaagac ggtaaaatta ccgctattaa tgttagtaaa ggagaatccg
    13441 tactcgaagg tactgacctt gtaattattg aataatatgg gagaatttat cacattttta
    13501 ggaaataacc ttgcagactt ctggacttat acaggttttg ccaatgcaac aggcggacat
    13561 ctggtaatga ttctggtagg tttattcttc atatacttgg ctgttgccaa ggaatttgag
    13621 ccgatgttgc tgattcctat cggtttcggt atgctgatcg gtaatatccc tttcaatatg
    13681 gaagccggat taaaagtcgg tatctatgag gaagggtctg tacttaacat tctgtatcaa
    13741 ggggtaactt ccggttggta tccgccactt attttcctgg gtatcggagc tatgacggat
    13801 ttctccgctc taatctctaa cccgaagctg atgctagtcg gtgctgccgc acaattcggt
    13861 attttcggtg catatatgac tgctttggct atcggattcg atccgatgca agctggtgct
    13921 atcggtatca tcggtggtgc cgatggtccg acagccattt tcctttcgtc caaactggct
    13981 cccaacctga tgggtgcaat tgccgtgtcc gcctattcct atatggcatt agtaccggta
    14041 atccaaccgc ctatcatgcg tctgctgacc agcaagaacg agcgccttat ccgcatgaaa
    14101 ccgccacgtg cagtttctca tacggaaaaa gtaatgttcc cgattatcgg tctgttactt
    14161 acctgtttcc ttgttccgtc cggtttgcct ttgttaggta tgctattttt cggtaactta
    14221 ctaaaagaga gtggtgtaac ccgccgtctg gctaacacag ccagcggtcc gctgattgat
    14281 accatcacaa ttctgcttgg tctgactgta ggtgcttcca cacaagcatc cgaattcctg
    14341 actacagact cattgtggat ttttggtctg ggtgcattct cattcattat cgcaaccgct
    14401 tccggtgtaa tcttcgtgaa gatattcaat atcttcctga agaaaggcaa caagattaat
    14461 ccgctgattg gtaatgcagg cgtatctgca gtgcctgact ccgcacgtat ctctcaagta
    14521 gtaggtttgg aatatgatcc aaccaactac ctgttgatgc atgccatggg tccgaacgta
    14581 gcgggcgtta tcggctcagc agtagctgcc ggtattctgt tgggattcct gatgtaagca
    14641 gtgaaaacgt ttgcataacc tgcataaagg ataatagcgg agaggtaaca gccttctccg
    14701 ctattttttt taatttagcg gagaaaataa cgaaaagcta atatcatgaa aaaagtattc
    14761 ttcattttag gaacactcct actttccctc agtacgtacg cagccatgaa cgtaaacaaa
    14821 atcgatccac cattttggta cactggtatg caaaaccccg aacttcagct aatggtatat
    14881 ggtgaaggca tcggcaatgc aacggtatct gtcaactatc ccggcgtctc gctgaacagc
    14941 acagtcaaat tggaaagcaa taattacctg ctggtctacc tcagactgga taaaaacgtg
    15001 aaacccggta aaatgccact caccttcacg caaggcaaga aaaagttcgt caaagaatat
    15061 gagctaaaag aacgtgccaa aaaaggctgc gagcacaaag gtttcgatgc atccgacgca
    15121 ctctatctgt taatgcccga ccgttttgcc aacggcaacc cggacaacga ccaaatagca
    15181 ggcatggcag aatataaggt agaccgcaac gacccaaatg ctcgtcatgg cggcgacctc
    15241 gcaggtatcg aacagcacct tgattacttt tccgatttgg gcgtaactgc cttgtggttt
    15301 actccggtat tggaaaacaa catgaccggc ggttcctacc acggctatgc caccaccgat
    15361 tattataaag tagatccccg cttcggcacc aatgaagagt ataagcagct catcgaaaaa
    15421 tctcatacac gcggcattaa aatcgtaatg gatatgattt tcaaccactg cggtgtagag
    15481 catatatgga taaaagacat gccttgcaaa gattggttca acaaccccga ccatgaaaat
    15541 aactttgtgc agacatcctt caaactgact ccccacgtag acccttatgc ttcgaaatac
    15601 gatttcagcc agatgaatga cggttggttc gtaaccgcca tgcccgacct caaccaaaag
    15661 aatccgcatg tataccgtta tctcgttcag aacagtttct ggtggattga atatgccgac
    15721 atagacggta tccgtatgga tacttacccc tatgccgact atgatgccat gagcaattgg
    15781 atgaaagagt tgaatgaaga ataccctaac tataacaccg taggcgaaac atgggtaacc
    15841 gaaccggcat ataccgcatg gtggcaaaag gactccaaac tgtccgctcc taaaaacagc
    15901 aatctgaaga cggtaatgga tttcagtttc tatgataaaa tcaacattgc caaaacggag
    15961 gaaacagaaa cttggtttaa aggattagac cgagtgtata acagtttcgt atatgatttt
    16021 ctttatccga atccggaatc ggtactcgct ttcatcgaga atcacgacac cgaccgcttt
    16081 ttgggtgaag gcgaaaacct tccgatgctg aaacaagcct ctaccctgtt actcaccacc
    16141 cgacgcattc cgcaattata ctacggaacg gagattatga tgaacggcat aaagagcaag
    16201 agcgacggtt atgttcgtaa agacttcccc ggcggctggg cagacgataa agaaaccgca
    16261 ctgacagccg aaggccgcag caaaattcaa aacgattgct acaatttcta caaaacaata
    16321 ctgaattggc gtaaaggaaa cgatgtgatt gccaaaggca gtatgactca gtttatggta
    16381 caaaacggcg tatatgccta tgcccgtcag tatgagggca aaattgtttt cgtaatgctg
    16441 aacggtacag attcagaaac caccgttcct ttaaaattct acaaagaaat tttgaaagac
    16501 aagaaacaag gaaaagatat tctaagcggc aaaacaattc tctttgaaaa agagttgaag
    16561 atggaagcgc gtgaatccct gatcatcgaa ttgtaaataa attcaggttt gacataaatc
    16621 aggtacggac taaatagaca cggataaatc cataaagtcc gtacctaaaa acaaataggg
    16681 agtgcattaa aatgcactcc ctatttttat aatcaaatta accttatcag tccaattgag
    16741 ccaatttgtt ttcagaacca agcacgttaa cgattttgtg cttgtaaagt ttctccatgt
    16801 tgtcacgagc cggacccaga tatttacgcg ggtcaaattc agccggtttc tcagcaaaca
    16861 ccttacgaac agcagcagtc atagccaaac gagagtctga gtcgatattg attttgcaaa
    16921 ctgcagactt cgcagccttg cgcagttgct cttcgggaat accgatagct gcttccaact
    16981 taccgccgaa ttgattgata gtatcaactt cttcctgagg aactgaagaa gaaccgtgaa
    17041 gaacgatagg gaatccagga agtttctcca ttacagcatc caatacggca aattccaaag
    17101 gaggaggaac cagacgacct gtagcaggat ctacgtggca ttgttcgggt ttgaacttgt
    17161 atgcaccatg agaagtaccg atagaaatag ccaaagagtc acaacctgta cgagtagcga
    17221 aatcgataac ttcttccgga ttggtataag tatggtgttc agcagatact tcatcttcta
    17281 caccagccaa cacgccaagt tcaccttcca ctgtaacatc gaattgatga gcatagtcaa
    17341 caaccttctt tgttaaagca acattttctt cgtatggaag atgtgaaccg tcaatcatta
    17401 ctgaggagaa acctgaatcg atacagcttt tacaagtttc aaaagtatct ccgtggtcaa
    17461 ggtgaagaac aatttcagga tgtttgcagc ccagttcctt agcatattcc acagcgccct
    17521 gagccatgta acgcagcaaa gtagcgttag catattggcg agcaccctta gatacctgaa
    17581 ggataaccgg agacttagtc tctactgcag ccttgatgat agcctgcatc tgttccatgt
    17641 tattgaagtt gaatgcaggg attgcatatc cacctttgat agcgcgagca aacatttctc
    17701 ttgtgtttac aaggcctaaa tctttgtaat taaccatttt gtttaaagtt tattgttagt
    17761 gaattaaaat tctacgcaaa agtaagcatt atcctttaaa aagaagaaca agagaagaat
    17821 aaaatacctc tactcaccag tcaaatccat tctattttaa agctattggc ttgaattaac
    17881 agaatattgt aatctctata ttacaaagtt tttgcatctg tctgttcatt ctctcctttt
    17941 gcgttcttac ctctataaac aaaaaagccg gaaagcgagt ttattttccg gcctgttatt
    18001 tacacattat tatatattat cttttcagat cattagtgtc ccgttaaaat gggacgagtt
    18061 aaacaattaa tcaaaaagcc ccggaatcag gggatcattt agatctttga catcattgaa
    18121 attagtcttg tcgaacaggt cacgcaagtg ggttttgtca gtcaatgata tgctgagaat
    18181 ttgtaaaact tcataggttg aacgtttcaa cttcatatca tgttggacaa tagccacaag
    18241 acagtacgtg ataatagcca cactgatttg tatgcgaaca gcgttctctg ttgtgcccca
    18301 gaatttcttt atcttgagat gctgcttgag ccatttgaag aacagctcga ttaaccatct
    18361 tttcttataa agatcggcga catccagtgc agaaagttgt tttgcattcg tcaaaaaagt
    18421 gaactcacgg tcatcctctt cgtcgtaata tcggacgagt ctgaatgact caggatattt
    18481 tttctcggag agatatccgg tcagtttcac ttccgcatct gtcattatgt tctttggcat
    18541 tcttcgcttc catctgactg tcttatactt taagttcgtc ttggctctga caacaaagaa
    18601 agagtctgta agatgtatcc tatagagttc tttaaaggag tcataagccc tgtcgaatat
    18661 ataataagca tttggttcat aatggattga agacattgct gtggaatcat gctttgatgc
    18721 agtagttaca gtatagaagg caggaacttg tgcttcaatg tcgtataaga catgagcttt
    18781 cacccctcct ttcttgcttc ggaactttgc ccatgggaat gttgcaagac acaacggaat
    18841 cgttgttgaa tcaaacgcat atttctttcc ggaaatgtca aggatgttgg tcgtccgctt
    18901 ctcgcaggct tccttcatca tatagaatgc aaagtcttcg aagattctgt aatcacggtt
    18961 ctggttcgct gtcgcaagag ttgtcttggc tatcggttca cgacctaaac caagatgata
    19021 ttgcttggcc ctatgcgcct cgaaagcaac gactaagtct cgcaggctct cacggttact
    19081 cagttgtcca aacatcatcg cgagcatctg attccagcaa gtgaaatgtt tcacatatct
    19141 gttgccatca tacttgcgaa catagttgtt gaactgagtc ctgttcagaa aagcggttaa
    19201 ttgagagaat acgtatttgt cttggaacat agcagccatt tgtattagac tgcaaagttg
    19261 caaaatcaag tccgtttcat ttcaaaaaac cgtgtaattg actatatttc aataatttca
    19321 aagaactatt tatccacttt tacgggacag tagtgttttc agatagataa tcgtaggtaa
    19381 atggtcgctg taaccgttca gccatacgcg cccgccatga gtacgcaaag gtgaaccttt
    19441 gtatttacca tcctgctgaa tcaggtagtc gcggataaaa acctcgctat ggtcgtaacg
    19501 cagtcctttt ttcgctttca ccaacggtct ggacagtaca atctggtcga acagattcca
    19561 cttgccacga tagagcaagg ttcccacacc cttatcctcc agtatttccc accagggatt
    19621 gaagaactga ttggctttca tacctgatat atatttacgg gcccctaaag tctgcatgct
    19681 ttcatccatc ggatcgtcat tcatatctcc cataacaaag agtttcagct ttttgtcttc
    19741 atgcatcaag gagtccgtca acgcctttac ctgcctggcg gcatgcaccc gcaccggtga
    19801 tttcgctccg cgggaaggcc agtgattcac aatgaaacac acacgctcac ccgccattct
    19861 accgtctaca ataaggaaac cgcgcgtcag atgcaccgta tccccttcaa acggagcgga
    19921 aagtaccagt ttagagttcg tcacggcaaa ctgttgcgga tcatacaaaa gtgcacagtc
    19981 aatgccacgt ctgtcgggtc cctcataatg aacaaactta tagttagcca tagccggctg
    20041 actgacaaga tccgtcagta ccctatgatt ctcgacttct gccacgccaa ttactgccgg
    20101 tccctcagga accagattac gcgacaaggc actcaacacg tccgagagat tatgcagttt
    20161 agcttcgtac tttttcgcag tccaccggta actgccatca ggcaggaagt catagtcatt
    20221 cttacctgca tcatggatgg tatcaaagag attctcaaga ttataaaacg ctatgctata
    20281 cagtttgcgt tccgtgttct gggctacaac tattgtagcg ctgaaccaaa aagaaaagaa
    20341 tacaatcagt tttctcatag gtgatatgat attaatctcc tgcaaaaatc taaaataaaa
    20401 agttataaac ctatcaattg ccagcttttt ttgcaaaaaa ccttttttca tttcatagaa
    20461 aagcattatc tttgcgcact gaaaaagacc attacactat ttattaccaa aatagtaaca
    20521 gaatataaat taaaaaacaa atattgaaat gaaaaaaggt attcatcctg aaaattaccg
    20581 tccggtagta tttaaagata tgtcaaacgg cgatgtgttc ttgtctcgtt ctacagtaaa
    20641 tactaaggag actatcgagt tcgaaggcga aacttatccg ttggtaaagt tggaaatctc
    20701 cagcacttct cacccgttct acactggtaa gtctaagttg gttgacacag ccggtcgtgt
    20761 tgataaattc atgagtcgtt acggtaaccg taagaaataa tctgtttttc aaagaaacgg
    20821 aaaaagggaa tctgctacag attccctttt ttactatatg catactaccc aacgtcagtc
    20881 ccatgcaaga cataatttcc acggaaaccg catcatcctg tttaggtaaa tcagactttc
    20941 ccgcgaaacg gcggacgcac caccacagcc ttcaacttac ggccgcgcat atcaatacag
    21001 atttccgtac caaccttact atattcgggc ttcacatacc ccataccgat accgatttta
    21061 cgggtaggcg acattgtgcc cgaagtaacc actccaatag gagtaccttc cggattctgt
    21121 aactcataac cgtgacgggg aataccgcga tctaccattt caaaaccgac caatttacgt
    21181 accgtaccct ccgtcttctg tttctccagc attggacgat tgataaagtt cttaccctct
    21241 acaaacttgg taatccatcc caatccagct tcaataggcg acgtggtatc atccaggtca
    21301 tttccataca ggcagaatcc catttcaagg cgaagcgtat cacgagcacc caaaccgata
    21361 ggtttgatac cgaactccgc accagcctca aacacggcat tccatatttt tattgcagct
    21421 tcaggataga aatagagttc aaaaccaccg gctccagtat aaccggtatt ggagattata
    21481 acatccggct cacctgcaaa ttcaccatgc gtaaaggtgt aatacgaaag ttcggaaaga
    21541 ttaacaggtg tcagtttctg caatgcttcg atagctttcg gaccttgtac cgcaagctgc
    21601 gccatacggt cggaagcatt ctccaactca gctcccatcg tattatgaga catacaccag
    21661 ttccagtctt tctcgatatt ggaagcattg actaccaaca gatatttctc ctgctcgtac
    21721 cggtagacca ataaatcgtc tacaataccg ccatcctcat tggggaagca agtatattgt
    21781 accttaccgg gagtaagggc tgctacgtta ttagaggtga ctgtctgtaa aaagtccaaa
    21841 gcatgcggac ctttcaccca aaactctccc atgtgggaga cgtcaaacac accgacaccc
    21901 tgacaaacag taagatgttc atcaatgata ccggaatatt cgataggcat attgtatccc
    21961 gcaaattcgt gcatcttagc tcccagcgag atgtgcgttt ctgtaaatgg agtggttttc
    22021 atggtgtgac ttataagtta tagattatga tttatttgtt agcggcaacg agttcggcta
    22081 tcttgacgat aacattcatg gctttctcca tattctgaat aggaataaat tcgtaacgtc
    22141 cgtggaaatt cagaccaccg gcaaagatgt tggggcacgg caagcctttg aacgaaagtt
    22201 gcgcaccgtc cgtaccgcca cgaatagctt ttacgtgagg ctctacaccg acggcttcca
    22261 tagctttaaa agctgtatcg atgatatgca tcaccggctc aatcttctca cgcatattat
    22321 aatattggtc atgtagttcg agtgcggctg taccctcgcc atattcggca ttaattttgc
    22381 agacaaggtg ttcaaattct ttcttgcggc tctcaaaacg gacacggtcg tgatcgcgaa
    22441 taatgtaagt aaccgtggtc tgctccactt cacccgtaat tccaataaga tgatagaagc
    22501 cctcgtaccc ctcggtatgt tccggtgttt cgtggctggg caacatggaa ataaaacgat
    22561 tggctacgcg gatagaattt atcatcttgt ttttggcata gcccggatgt acattgcgtc
    22621 ccttgaaaac aatcttggca gaagccgcat tgaagttctc gaactccagt tcgcctactt
    22681 caccgccatc catagtataa gcccattcgc aaccgaattg ctcaacattg aatttatgcg
    22741 cacccaaacc gatttcctca tcgggattga aaccgatacg gattttacca tgtttgattt
    22801 cagggtgttc tttcagataa gctactgccg aaacaatctc cgcaataccg gctttgtcat
    22861 cggcacccaa taatgttttt ccgttagtaa caatcaaatc ttctccctta tggtcgagca
    22921 attcggggaa tcgagcagga gaaagaacta cttgctcatc tgcgcaaaga acaatgtcct
    22981 ttccatcata attctctaca atgcgcgggg aaacatcttt cccgctcata tcgggactag
    23041 tatccatatg ggcaatgaag ccgacaacag gtacagactt atctatattg gcaggaagag
    23101 tggcaaacag ataaccgttc tcatccaatg taatctcttc caaccccaaa gcttccaatt
    23161 cttctttcaa gaacctggca aataccattt gccccggagt actcggagtt accccacttt
    23221 cctcattcga ttgcgtatcg aaacttacat actttaaaaa acgttctact aaagtcatga
    23281 tgatagtgat tatagttagt gattagcgat tagtggttag tgatgaacga ttaacggtca
    23341 gtaggctaca accgcgccct ccttttatcc gaacggcatt aatcacttat cactaaaccc
    23401 taatcactat tttactgccg taaaattaaa aaaaggattg tgaactgcca agcaattcac
    23461 gacccttttt cattcattaa taactatttt gtcaatcaaa agtgactgct accatcaaaa
    23521 caatgggtac aaagtttaca tttaggcaga ccaatagcct caaccaatgt ttccagcgta
    23581 ttgaacttta atgatgacag tccaaaacgc tcacggataa cttctaccat tttctcgtac
    23641 tccggcgaac ctgtagtggc atatttctca agatttttgt tttcatcacc ttccaactcc
    23701 ttaatgacac ggcgggtaat caactccaaa tctcctttgg atgctgtgaa gccaacaaac
    23761 ggacagctat atatcaacgg cggacaggca atacgaatat gtacttcttt cgctccatac
    23821 tcataaagca cctttacatt atcgcgcaac tgagttccac ggacaatgga atcgtcacaa
    23881 aacagaaggc gtttaccttc cagcatggca cggttgggaa tgagtttcat ctttgccacc
    23941 aacgaacgca tttcctgcct gctgggagtg aaactacgcg gccaagtcgg agtatatttt
    24001 gaaatggcgc gatgataagg cactcccttt ccttcggcat atcccagcgc cataccgaca
    24061 ccggaatcgg gtatgccgca cgtacaatct acttccgagg tatcggtctg tcccattttc
    24121 agtccggaaa caaagcgtac atcttccaca ttctttccct catagcatga agtgggaaag
    24181 ccataataaa cccataggaa agaacatatc tgcatctcct cattaggttt gcgcatctgt
    24241 tccacccctt ctgcatgcag acggacaatc tcgcccggtc ccagatagcg gtctatttca
    24301 tatcccaagt tcgggaaact actcgattcg cttgtggctg catatgctcc atctttctta
    24361 ccgataacaa tgggagtgcg cccccaacgg tcgcgggcgg caataatgcc gtcttcagtc
    24421 agcagcagca tggaacatga acctttaata tgcttgtata cattctcaat gccgtctaca
    24481 aaagtcttac cttgtatcag cagcaaagcg ataagttccg tttgattggt tttgccggag
    24541 cttaattcgg caaagtgcat attttgctcc agaagttcgg tttccaactc tttcaggttc
    24601 ataatcttgg caaccgtaac tatggcaaaa cgaccga
//
