LOCUS       NC_009437.1            23178 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_009437.1 Caldicellulosiruptor saccharolyticus DSM 8903, complete
            sequence.
ACCESSION   NC_009437
VERSION     NC_009437.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:16:01
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1286809
            Orig. end    :: 1309987
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23178
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1296809:1299987]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13178
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23178
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23178
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="3"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2002..3288)
                     /locus_tag="ctg1_1182"
                     /transl_table=11
                     /translation="LKYTQNEKILQVTERTLVVGVDIAKERHVGRAFDFRGVELGKRIE
                     FENRKEGMEKFLDWANKIMKANGKDNMIVGIEPTGHYWLCFEQYLRENGIKVVLVNPFH
                     VKRSKELDDNTQTKSDIKDPKTIAMLVKDGRYTEPNIPEGIYAEMRVAMNIYERLQKQL
                     NVLKNQIINWLDMYFPEFLEVFSDWEGKVALLTLKEMPLPCDVVENEVEGIIEYWRDKV
                     DRRAVSRRRAMDLVEAAKRSIGKKEGRKLARQEIKYLLSQYELLKKQIEEIEAEMAELL
                     REVPNGEELLKIKGVGVKTAVGFISEVGDIKRYEDARQIQKLAGLNIVENSSGKYKGQT
                     CISKRGRGRLRSSLFKAMITIVAKNEEFKQLHRYYTTRENNPLKKKQSLIALCCKLIRV
                     FYAILKKGVKYDGNKMLSDIKREALARTA"
     CDS             3753..4160
                     /locus_tag="ctg1_1183"
                     /transl_table=11
                     /translation="MESKLFETRKNQKIAILTVALLSVIFLTIFSVRAENTVTYVSLPV
                     KLVQQAYSNWCWAAGSESILYYCKNYLDFGREATQWDIVKYIYGSYVNKPASLYDIQRA
                     LELLWCWFFTHDTSKWLDNFIWANCRANCKL"
     CDS             4407..5393
                     /locus_tag="ctg1_1184"
                     /transl_table=11
                     /translation="MKKNKVYIGFVMTFLLLFFTTFSATGASYSIEHNDEINILRRQYL
                     AESWLNLYISTLIKNYIKDSPTLQSLNEITNINGAYDIEKFKLSKEYEYYRVFHIPTEV
                     KIAKNGRPYHIVRDEVKEKVKNLRFSSWKDVFNTEFVDNRWARIVYYDNLPVGYLLIEW
                     DRKMNNYIVNTGVFGDDSLGNAVENLEKYLTQRGVKSDVKIVNIEEMTLYAVSGDGNWW
                     CAGAKGYENHIWDFGIIKDALNKKPIQILNAIEKRSRLMREAHEKIMIGGEDPSKTLYF
                     AAAKKEKTQNAMIAIYLLILTAVVVICSKWKFSYQHLFHKHVRNRQK"
     CDS             complement(5489..5983)
                     /locus_tag="ctg1_1185"
                     /transl_table=11
                     /translation="MSKKIENILKFGMKMEKNAQDFYSFYANSLQDENLKKLFEEFVKI
                     EQEHYKYLENILKSLGSQEPPISISWVVDDQNKMVDPHILVDNSKILETDFSDLTILRL
                     AYLIESDFAAFYKHVAEKVEDGNVKGLLLHLAKWEEEHEKYFKERYHSLMKKEWEEIDL
                     F"
     CDS             complement(6160..6660)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1186"
                     /sec_met_domain="Acetyltransf_1 (E-value: 4.1e-12,
                     bitscore: 43.8, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSYIRLAKIEDVAIMSRIHALTWKEAYKGLIPQEYLNGISEDKWI
                     KPFIDALSNKLHEAAIINNGETDAGCVCFGKSRDGEAGYGKIISIYVLPAYWSTRQGYE
                     LMNFALNRLKKQNFDYCHLWVLEGNTRALNFYERYGFRSDNKVRIINIVGVNLRELRYS
                     IKL"
     CDS             7100..7207
                     /locus_tag="ctg1_1187"
                     /transl_table=11
                     /translation="MMESPLKLIIYFNISKKKIISILNKVLDEDKKKFC"
     CDS             7349..8164
                     /locus_tag="ctg1_1188"
                     /transl_table=11
                     /translation="MIIDFHTHCFPDELAPRAMSKLSQNSGMPYYHNGTLSGLKESAKK
                     AGIDMCVVLPIATKPQQTRTINKWALSVMEENKDIICFGTVHPEFDEWKEEIRWLKENG
                     FAGIKFHPDYQDFFVDDIKMYPIYDAIFQNDMIILFHSGVDPAFMPPYHCTPKKLHKVL
                     KDFSGTKIVAAHMGGYRFFEETLECLIGEDVYLDTSFFFGEVDIQNPEEIFRNHGIDKI
                     LFATDSPWKDQKREVEYVNSLRLSEEEKEKIFWKNAQQLLGLKIVHRAK"
     CDS             8222..9010
                     /locus_tag="ctg1_1189"
                     /transl_table=11
                     /translation="LRAKIIVNNWTFKGGYLAEHGLSILIEKDEKRILFDCGQTNAIVK
                     NIEKMGVDFDFDAIVLSHAHYDHIGGLKFLIDKTDCNIWVHNGFFEKKFAKREGEYKFI
                     GESFEGFEMARFKIVNEDVYEVFDGIYLVNAISGKESEEFYILKDGKYQKDTFIEEQSL
                     VVKEDDKLILIVGCSHNGIENIIGKVEKYFSKSIFAVIGGFHLKNFQQDDFKELCEFFK
                     NKRIYKLVPLHCSGTEALIHFGNKMANKLKVCGVGDVIEI"
     CDS             9037..9843
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1190"
                     /sec_met_domain="adh_short (E-value: 1.6e-46, bitscore:
                     155.6, seeds: 44, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKDFWEDKIVIITGVTSGLGKEMTKILLKKGAKVVAISRSKESL
                     KGLQNELISFSKNLFLIKADVSFRKDCEDAFKIIKDKLKTADFLINNAGVGLRCEVEEI
                     EDLDLKRVFDTNFFGAFYMMKYGIAFFKELGGGTIVNICSLGVKRPVPFTGGYTASKAA
                     LSTIADVARMELKKYNINILNAYPGSILTSFRKKALGKPYPEDEVRLSRLSPDVAARRI
                     IRGIEKSRKEIYTSKKDYIFVLFTRLFPHISDFIVEKAFEKRLKGL"
     CDS             10001..11611
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1191"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-47, bitscore:
                     158.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNKMTVARAMVEVLRSEGVEIIFGIPGAAIYPFYDALYDSNIKH
                     VLVRTEQAAVHEASGFARTTGKVGVCVATSGPGATNLITGIATAYMDSVPIVAITGQVN
                     SSLIGRDVFQEVDITGATAPFTKHNYLVKDPKKIVKILKEAFYIASTGRHGPVLIDVPI
                     DVQMQEIEFELPKDIDIPGYKPKEKGHPLQIKRAVEAIENSQRPVICSGGGVIASRASD
                     ELKILVEKQKIPVISTLMGIGCIPTDHPYYLGMIGSHGQKEANLALRQADLLIVIGARL
                     ADRALGDTKVTDNMKIIHIDIDPAEIGKNVDTNVPIVGDAKQVLSEINKRISERKDFWA
                     HEIKAQKKVLPDDDKLHPCDVLREISRAYNGDYIITTDVGQHQIWAAHNLYIKEPGTFI
                     TSGGLGTMGYGVPAAIGAKFGRPDKEVISITGDGSFQMLLQELATIKREQVPIKIVLFN
                     NTRLGMVYELQKKRCTGRFIATCLDGNPDFMILAKAYGIESMRLESKEKLKEAIETMKS
                     HKGPFLLEVVTSPDEPTIP"
     CDS             11662..12174
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1192"
                     /sec_met_domain="ALS_ss_C (E-value: 4e-33, bitscore: 110.9,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKYTLSVLVENHPGVLSRVAGLFSRRGFNIDSLAVGVTEDPTISR
                     MTIVVNGDDYIVEQVTKQLNKLIDVIKVKKLNPKEAVERELALIKVNANSQTRSDIIQI
                     TEIFRANIVDVSKETLTIEISGDEDKIEALIELLKQYGIREVVRTGLIAIERGNKVISK
                     SKSEEDD"
     CDS             12177..13178
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1193"
                     /sec_met_domain="IlvN (E-value: 2.2e-80, bitscore: 265.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.7e-69, bitscore: 230.1,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIFYDQDCNLDLLKDKTVAVIGFGSQGHAHALNLRDSGINVVV
                     GLYHGSKSWAKAESHGLKVMTADEATKAADIIMILVNDEKQPKLYKESIEPNLKEGKAI
                     AFAHGFNIHFGQIVPPPYVDVIMIAPKGPGHTVRSQYEEGKGVPALVAVHQDYTGKALD
                     IALAYAKGIGASRAGIILTTFKEETETDLFGEQAVLCGGLTELIKAGFDTLVEAGYQPE
                     IAYFECLHEMKLIVDLIWQGGLSLMRYSISDTAEYGDYMTGKRIITEETRKEMKKVLEE
                     IQNGTFAKKWILENMAGRPEFNSIRRREQNLLIEQVGKELRKMMPWIKPIKE"
     CDS             13195..14718
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1194"
                     /sec_met_domain="HMGL-like (E-value: 2.4e-106, bitscore:
                     352.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKRVIKIFDTTLRDGEQTPGVSLNVNEKLEIAKQLEKLKVDVIE
                     AGFAIASPGDFEAIKTISENIKDAVVVSLARAIEKDIDRAYEALKKASSPRIHTFIATS
                     DIHMKYKLKMTEDEVLERAVAMVKYAKKYVSDVEFSCEDATRSRIEFLIKVFDAVIKAG
                     ATVINIPDTVGYTTPEEMKRIIRALKENIPDIDKVQISVHCHNDLGLAVANSLAAVEEG
                     VHQVECTINGLGERAGNAALEEIVMALKTRKDFYDVDVLIDTTQIYRTSKLVSSLTGVF
                     VQPNKAIVGANAFAHESGIHQHGVLSERTTYEIIDPVSIGLPKNRMVLGKHSGRHAFEE
                     RLKELGYTDLTREEIDAAFEKFKVLADKKKVVLDKDIEALLEQKSLNIPETYELVKFQI
                     ISGNDLISTASVKIKSGEEEYEEAATGDGPVDAIFKAIDRITGLQVELDDYSIKAVTQG
                     KDALGEVTVRIKKDGKAFLGRGLSTDILEASAKAYVNAINKMLYKISEE"
     CDS             14797..14961
                     /locus_tag="ctg1_1195"
                     /transl_table=11
                     /translation="MIIRICGAITIISIISIIRKRIIKWIYKISYAALHPFWPVYEQRG
                     FLKRPLGHL"
     CDS             15055..16635
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1196"
                     /sec_met_domain="HMGL-like (E-value: 8.3e-52, bitscore:
                     173.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEDNKTIIIYDSTLRDGAQAGGISYTLEDKLKIVERLDKFGVKFI
                     EAGNPGSNIKDQEFFARVKKMKLKNAKLIAFGSTRRVGIDVKDDINIQSLIAANTEAVA
                     IFGKSWDFHVKEVLKTTEDENLQMIYDTIKYLKSLGKYVVFDAEHFFDGYKNNRKYALE
                     TLKVAKEAGADSLDLCDTNGGTFPMDIYNITKEVVEMFPGTLIGIHCHNDTGMAVANSI
                     MAVLAGARQVQGTINGYGERCGNADLITLIPNLQLKLGFKCVPDENIKHLTSLSRYVAE
                     IANMIPNERAPYVGAYAFTHKAGMHIDAVKKNPASFEHVNPEIVGNTRRIVLSEVAGRS
                     TILDKIREIDPTVTKDSPVTKEIIDELKRLENEGYQFESAEASFEMLIRKKLGLYQPFF
                     TLKEFKVLINEPAVEYSSSAIVKIAVDGVTAITAAEGDGPVHALDNALRKALEKFYPEL
                     KEVHLVDYKVRVLNAETATAAKVRVLIESTDGKDTWTTVGVSTDIVNASWIALVDSLEY
                     KLCKEKVGK"
     CDS             complement(17092..17367)
                     /locus_tag="ctg1_1197"
                     /transl_table=11
                     /translation="MGKLGIKEKSKIKIFIYDKRSTFQTKRYGLITLLFNLDWYIGDNL
                     GSTVILTSPSNPGKLHNSESVKQPLLHEMDHAYEYLINPKIKKWLN"
     CDS             17735..18073
                     /locus_tag="ctg1_1198"
                     /transl_table=11
                     /translation="MNNTKKDMQFLVIKGYNAKNNKIFLSSRNVRLKPQTIDTKVISGV
                     PTYLKNVQVEIVQSKSVPSFVVDWYFNKQGSLYIVGINNSERDDNLLVKVEACDQKGQK
                     IWVGFEKL"
     CDS             18027..18236
                     /locus_tag="ctg1_1199"
                     /transl_table=11
                     /translation="VTKKVRKFGLGSRNFRVLKVTIDTCIVNNIPAYVKKVNVSVLPEQ
                     DGVKTQEKLFDRERTNIVYYYYKL"
     CDS             18211..18399
                     /locus_tag="ctg1_1200"
                     /transl_table=11
                     /translation="LYIIITNYENDKNIKIQVNGFDANGRLVYKSIYNADAKSNIVEAH
                     TINISNSKIERVEINVK"
     CDS             complement(18486..19097)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1201"
                     /sec_met_domain="LysM (E-value: 4.5e-17, bitscore: 59.3,
                     seeds: 155, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKALAVLSIIALLSFSTAFAQTKTYTVQAGDTIWSIAVKNQIGI
                     SELLKANPQIKNPNLIYPGQKINIPNSNNLNVLENEVIKLTNQERAKVGLSALKTNWQL
                     CRVARFKSQDMANKNYFSHYSPTYGSPFKMMENFGLKFMAAGENIAYGQRSAQEVVRAW
                     MSSPGHRANILSPSFTEIGVGVAKKSNGVLYWTQMFMRPY"
     CDS             complement(19481..19711)
                     /locus_tag="ctg1_1202"
                     /transl_table=11
                     /translation="MGEKFNRVFKSVTSDNGSEASRLGKVLNELGSEGYYTHPYSHMRG
                     EQTSGQIELIRCFLPKRKEISKISKEAIKRS"
     CDS             20319..20729
                     /locus_tag="ctg1_1203"
                     /transl_table=11
                     /translation="MKEKSFPKISKAELEVMKVVWKENRVLSGREIVTKVMETNKKWHK
                     NTIFTLIDRLAKKGVLKVEKKGKFNFYTASITEEDYKKEEARDILQRMFGGSFRNVIAT
                     FLETTNVSKKEIEEIKKMLDEKGCCKYDNGSF"
     CDS             21704..21907
                     /locus_tag="ctg1_1204"
                     /transl_table=11
                     /translation="MTVVRQRDRVKAKIKKSNHFSKISEGIAIVEDDKGLKGFYVFSSD
                     KKLDVDNAKTERWYLKNLKLFQ"
     CDS             complement(22015..23157)
                     /locus_tag="ctg1_1205"
                     /transl_table=11
                     /translation="MLENTSYQMKRRSVDELIQHLKTFELDLKFSVGIWYFSDHPSRFH
                     APLGEPKTIEERLEIIAKLKDYGVCALEAHYPNEINEDNLELYKKFSRDTGIKILSVIP
                     NLFYENDFEFSSLASPIEEVRKKAIERLKTSLMLNKELDCEFCIIWPGGDGYENQFGID
                     FIRMRDRFAEGIAEAMDAVPGVKVAIEPKPYEPRGRIIYGLTGEGILLAQKVEKLLQNP
                     ENKKILEDDSLVGLNPEVGHVLMGFEDLAYAFSLALEYGKLYHTHWNSQPLGNYDQDLN
                     VGVISPEQAEAALYVMKMYGYRGYFGIDINPERMPVERAVINSIDAIKAMNDRINNLPH
                     EDIIACTEKPHKNRGLLEAILIRARANNPSILSPMPKVER"
ORIGIN
        1 ttgtaatatt gttagggaaa accactttaa caatatagtc agcatttact cttatggaag
       61 tatatcacaa ggaaattttg aaaaaaaata tagtgatgct gacttatggt tcataataga
      121 atgcaaatct atacaagaaa ggataagttt agtaaaagaa atgtcagcta taattgattg
      181 tgaaataaaa aaatatttgg ataaagttca taatgtaaaa aaagacagaa agtatcacta
      241 ccatggtagt ttatttttta cacaaattga atttgaaaaa tattataatt cttatcctac
      301 aagagtcata tacccaataa aaaagaaaat ttggaaatta atttacggaa aagacttact
      361 tgaaaaggtt gaaattcctg atcgcaaaat atgcgtcaaa catttacaat acgattttga
      421 agtttttgtt catgaattta ataaattatc tttttctagt aatacaagaa acatgataaa
      481 atatttttta agagctatac aaacggttat ttggatttta aaggatatat atttgccttg
      541 tatagatgaa gttcttgaaa aagctgatgt aattctcagt gatgataaac tattacctta
      601 tgtaatagaa aaaatcaaat acgcaaaaag cattagttat aagttatcag gagtcgaata
      661 tctagagttg tttttaaatt gcagcacact tctcgaaata tatggaaaaa aaataaattg
      721 ttatgtttgc aagagtggtt attctctgct agacataaat aaatttatag aaacaaccat
      781 atggggctgt ttggcgtggg atatggcttg tctgattaac ggatggtgta acatgataaa
      841 taaaaaatct aaaatgacat tgttagaatt tattgaagga gatggttata aaagaaggat
      901 gcagtatttt aactatataa taacaagaaa attaagagca gaagaagtag gtttatcagt
      961 atgggagatg ccagcaatga gaagtaggat attaaatcct attcagataa ataaagacgt
     1021 atgcaaagat atacttgata taccagcata tatgttttta attgaggaac atatgaacaa
     1081 cattataaac aaaaaattct caaaaatgaa tattagtcag ttaattgaat atgcagagaa
     1141 aaaatatata ccagctgttt atgaagtatt tgaaaggctt cttaaaaccg actaatacaa
     1201 aatcaaatta tgtattgaag tactaataag tttcaagaaa taaactttta agcttatttt
     1261 gtatttttgt ttacaaagag tcctcagaat attttatcaa tattaaaact ttctattcta
     1321 tttaacaaaa ctttaactat cgataaagta aggaaattcc aaagttaaac aagctatttg
     1381 ttatattgtc ttcggtatca actcaagaga ggtaaaaaag atatcttccc tctctcaata
     1441 tacctttgat tttctcaaaa tatctcacgg tttctttaaa tttcgttatc gaaacaaaca
     1501 attttgttct tgatattgtt attattgctt tattctacca tgcccaactt agaattggcc
     1561 tccatcttgt atttatcttg ttattctacc atattacggc gggtatttat ccacaataac
     1621 catggcgttt accctctcat gtctctcagg gtcttttctc acttgccctc aattccctcg
     1681 tcccatctac catggcgtgg acgtcagtta tgctcgtatg cagggtcttc gcccgtatgg
     1741 gggatgtact ctgaccaccc gctcacattt tccaatctac ttacttttta taaagaatca
     1801 ttttatcctt ctttcttcac ttgttactct ttatacattg tttaagatgt gaactcctac
     1861 caaaaggggc gctttgctac tcgacatgac ttaatctcct cgcaaagcta agaatttctt
     1921 taccccctca agatgtgaat cactcaaact atttctcctg ctttaaacta agaatgttca
     1981 agcaattttt ctcacttcac ttcacgctgt ccttgctaaa gcctctctct ttatatcgct
     2041 caacatcttg ttcccatcat actttacgcc ttttttcaaa atcgcataaa atacccttat
     2101 caatttacaa cacagtgcta ttaatgattg cttcttcttc aagggattgt tctctcgcgt
     2161 ggtgtaatac ctgtgcagct gcttaaattc ttcattcttt gctactattg taatcatggc
     2221 cttgaacaag ctacttctga gcctccctcg ccctctttta cttatacacg tctgaccctt
     2281 gtacttgcca gaactattct caactatatt gagtcccgcc aatttctgta tctgtctcgc
     2341 atcctcatac ctctttatat ctccaacctc agaaataaag ccaactgccg tttttacacc
     2401 aacacctttt attttaagca gttcctctcc attcggcacc tctctcaaaa gctctgccat
     2461 ctcggcttct atctcttcta tctgcttctt taaaagctca tattgactca gcaaatattt
     2521 tatctcttgt cttgccagct ttctcccttc ttttttacct atactccttt tggcagcctc
     2581 tactaaatcc atcgccctcc tgcgactaac cgctcgccta tctactttgt cacgccagta
     2641 ctctataatc ccttccactt cattttccac tacatcacaa ggcaatggca tctcttttag
     2701 ggtcaatagc gctaccttgc cttcccaatc agaaaatact tctaaaaact ctggaaaata
     2761 catatcgagc cagttgatta tttgattttt taaaacgttc agctgttttt gaagcctttc
     2821 atatatgttc atcgctactc tcatctcagc atatataccc tcgggtatat ttggctctgt
     2881 atatcttcca tccttcacaa gcatcgctat cgtcttcgga tcctttatat cgctcttagt
     2941 ttgcgtatta tcatcaagct ccttgctcct cttcacgtga aaaggattca ctaaaaccac
     3001 ttttatgcca ttctctctca gatactgctc aaagcacagc cagtaatgcc ctgtaggctc
     3061 tatccctact atcatgttgt ctttgccatt tgctttcatt atcttatttg cccaatccaa
     3121 aaatttctcc ataccttctt tcctattctc aaactctatt ctcttgccaa gctccactcc
     3181 tctaaaatca aatgctctgc ctacatgcct ttcctttgct atatctactc ctacaactaa
     3241 agttctctct gttacttgta atatcttttc attttgtgta tacttcaaag agggtacctc
     3301 ctttgttgtg ttttgtcgta agttgtacaa cttacattct gtattttacc aggaggtacc
     3361 ttatctcttc aaatctcatt tctcttcatt ttcactcatt ttcgttcatt acaggaatgc
     3421 tggtatatac actttcttat gctcccaaaa agtctttgtc aattcttggc atagctttat
     3481 tctctcctga ttaaatatga attatctttt tcatcaaaca taaaatatta tctcatacca
     3541 aaaatactcc atgataaaaa agatacattt ttaaacacat tatttttata aaatttatgt
     3601 tatgtgcatt tttttgatgt tttctgtaga taaattttta caaattggga ttcaaaaaat
     3661 taaaaaaaga caattttaca cattgaaaat cagaaaccat aagtattaaa ttatatacag
     3721 aagtttaatt gataagaaat gataggataa aaatggaatc aaaacttttt gaaacaagaa
     3781 agaaccaaaa aatagcaatt ttaacagtgg cactgctgag tgtgattttt ctaactattt
     3841 ttagtgtacg tgcagagaac acagttacat atgttagtct cccagttaaa ttagtgcagc
     3901 aagcatattc aaattggtgc tgggcagcag ggagcgagtc aatactttac tattgcaaaa
     3961 actatttaga ttttgggaga gaggcaacac agtgggatat agtgaaatat atttatggaa
     4021 gctatgtaaa taaacctgca tctctttatg atatacaaag agcacttgag ctattatggt
     4081 gttggttctt cacgcatgat accagtaagt ggcttgataa tttcatatgg gcaaattgca
     4141 gagcaaattg taaattataa aagtccaatt aggatcagta attacagcaa cagtaagtca
     4201 aaatcatttt gttgttttaa atggtatatg gcaatatttt gactcaaatg gatatctaca
     4261 aaattatata atgattatgg atccagctat aggtggggta attagtattc ctgattctga
     4321 gttgagggat aatgacaatt accaggatta cttagatgcg ataagagtat ttaaaccata
     4381 ttgatataac aggggggtga aatagaatga aaaagaataa ggtatatatt ggttttgtaa
     4441 tgaccttttt gttgcttttc tttacgacat tttcagctac tggagcaagc tattcaatcg
     4501 aacacaatga tgaaattaat atactcagaa ggcagtattt agccgagtca tggctcaacc
     4561 tttatatcag tactcttatt aaaaattata taaaagactc acctacgctg caatcgttaa
     4621 atgaaataac aaatatcaat ggagcgtatg acattgaaaa attcaagttg agcaaagagt
     4681 atgaatatta cagggtattt catattccaa ctgaagttaa gatagctaaa aatgggcgcc
     4741 catatcatat tgtaagagat gaagtaaaag aaaaagttaa aaatttgaga tttagctctt
     4801 ggaaagatgt ttttaatact gaatttgtag acaatagatg ggcaagaatt gtatattacg
     4861 ataatctacc tgttggatat cttcttatcg agtgggatag gaaaatgaac aattatatag
     4921 tgaatactgg agtgtttggt gatgattcat tgggtaatgc agtagaaaat ttggaaaaat
     4981 atttgacaca gcggggcgtt aagagtgatg taaaaattgt caatattgaa gaaatgacat
     5041 tatacgcagt atcaggtgat ggaaattggt ggtgtgctgg tgcaaaaggt tacgaaaatc
     5101 atatatggga ttttggcata ataaaagatg cgttaaacaa aaaaccaatt caaattttaa
     5161 acgctataga aaaaagaagt agattgatga gggaagctca tgaaaagata atgataggtg
     5221 gggaagaccc atcaaagaca ttatactttg ctgctgccaa aaaagaaaaa actcagaatg
     5281 ccatgattgc tatatactta ctaatcctga ctgctgttgt tgttatatgc tcaaagtgga
     5341 aattttctta ccagcatcta ttccacaaac atgttagaaa tagacaaaag taaaactatg
     5401 ctcaaaaata attcacacaa aaatttaaag ggagctgtct aaaaaataga ataaagactg
     5461 ctcccttact gctttttgta ggtctttttt aaaacaaatc aatttcttcc cactcttttt
     5521 tcataaggct atggtacctt tctttgaaat atttttcatg ttcctcttcc cacttggcaa
     5581 gatgtagaag caaacctttt acattgccat cttcaacctt ttcagcaacg tgtttataaa
     5641 atgcagcaaa gtcgctttca atcaggtatg caagccttaa aattgtaagg tctgaaaagt
     5701 cagtttccaa aatcttggag ttatcaacta atatgtgcgg gtctaccatt ttgttctggt
     5761 catctacaac ccatgaaatt gaaattggtg gttcttggct gcccagactt tttagaatat
     5821 tctcaagata cttataatgt tcttgctcaa tctttacaaa ctcttcaaaa agtttcttaa
     5881 gattttcatc ctgcaggcta tttgcgtaga aagaataaaa gtcttgcgca tttttctcca
     5941 tcttcattcc aaacttcaat atgttctcaa tctttttact catcacaagg tctctccttt
     6001 taataagatt tttttctcaa agatatttat acccaaaagc ttgtattaaa aacttaaaat
     6061 aaatcatatc gaaaaatata aatgattcaa aaggctattt tctgttccta tcctatagcc
     6121 tttttaaatt ctttatcttc tttatttgac agactaatat tataatttaa tagaatacct
     6181 taattctctc aaatttaccc ctacaatatt aattattctt actttattat cacttctgaa
     6241 cccatacctt tcataaaaat tcaaagctct cgtattacct tccaaaaccc aaaggtgaca
     6301 ataatcaaaa ttttgctttt tcaatctatt taaagcaaaa ttcattaatt cataaccttg
     6361 cctggttgac caatatgctg gtaaaacata tatagatatg atctttccat atccagcttc
     6421 tccatcacgc gatttaccaa aacaaacaca tccagcatca gtttctccat tatttattat
     6481 cgccgcttca tgcaatttat tagataacgc atcgataaat ggcttgatcc atttatcttc
     6541 cgaaatccca tttagatatt cttgcggtat caaaccttta taagcttctt tccacgttaa
     6601 agcgtgtatt ctactcataa tagctacatc ttcaatttta gctaacctta tataactcaa
     6661 ttattctctc cccccgttat tcaagtattt atatctacaa ttcataattt aagcagaaac
     6721 cttttttact ttatactttg ttcagaatct gatataagta ctgttctact tctgcaccgc
     6781 atggcacata caattaaata aacttcggaa agccaaagaa cttttcagca aagacaatag
     6841 ccaattttag ttttttacac acaatttttt tgctactaca ggaaaagttt tctaatgttt
     6901 tttctcctgt acttttgtat aacttataac ttaatctaat aaataccata gaaatataga
     6961 atgttataaa gttattcttt gtgattttat agtttttagt ctgttagtaa tccttagtaa
     7021 atcacccctc gactctttgg tatatttgaa aatagaataa gaagaacgaa gttattgaat
     7081 tagaaggcaa aagttttaga tgatggaatc acctctcaag ttaattattt actttaatat
     7141 tagcaaaaaa aaaataatta gcattttaaa taaagtttta gatgaagaca aaaagaaatt
     7201 ttgttaataa ctaataaggg aactatggta aaatattaaa actagagata agttttaaaa
     7261 aattttttgc tccagccacc tgaaaatgaa aagtgcttgc aataatcaaa tgaaaaattt
     7321 agaaaagaaa aaaggagagt aggagagtat gattatagac tttcacaccc actgttttcc
     7381 agatgaactt gcaccaagag caatgtcaaa gctttcacaa aattctggta tgccatatta
     7441 tcacaatggt actttgtcag gtttgaaaga gtctgctaaa aaagctggaa ttgacatgtg
     7501 tgtagttctg cccattgcaa caaaacctca gcaaacaagg acaattaaca aatgggcctt
     7561 gtcggtaatg gaagaaaaca aggacataat ttgttttggc acagttcatc ctgagtttga
     7621 tgaatggaaa gaagagataa ggtggttaaa agaaaacggg tttgctggaa taaaatttca
     7681 ccctgattat caggattttt ttgtggatga cataaagatg tatccaatct atgatgctat
     7741 tttccaaaac gatatgatta tactttttca cagtggagtt gacccggctt ttatgccacc
     7801 ttaccattgt acaccaaaaa agcttcataa ggtcctaaaa gatttttcgg gtacaaagat
     7861 agttgcagcg catatgggtg ggtacagatt ttttgaagag acgcttgagt gcttgatagg
     7921 tgaagatgtg tatcttgata catccttttt ctttggtgag gttgatatac aaaatccaga
     7981 agagattttc agaaatcatg ggatagataa gattttattt gcaacagact ctccatggaa
     8041 agaccagaaa agagaagttg agtatgtaaa tagcttaaga ctttctgaag aagagaaaga
     8101 aaagattttt tggaagaatg cacagcagct acttggactt aaaattgtcc atagggcaaa
     8161 gtgagatgtt ttgctcaaag gtcactcaac agcaaatatt agaaagagag gctttttaaa
     8221 attgagagcc aaaataattg tcaataattg gacgttcaaa ggtgggtatt tagcagaaca
     8281 cggtctttca attttgattg aaaaagatga gaaaagaatt ttgtttgact gtggacagac
     8341 aaatgccata gtgaaaaaca ttgagaagat gggtgtagac tttgattttg atgcaattgt
     8401 tctgagccat gcccattatg accacatagg tggtcttaaa tttcttattg ataaaacaga
     8461 ttgtaatatt tgggtgcaca atggattttt tgagaaaaag tttgccaaaa gagaagggga
     8521 gtataaattt ataggtgaaa gttttgaagg gtttgagatg gcaagattta agattgtcaa
     8581 tgaagatgtc tatgaggtat ttgatggtat atatttggtg aatgctatct caggcaaaga
     8641 gtctgaagag ttttacattc tgaaagatgg caaataccaa aaagatacat ttatagaaga
     8701 gcaatctctt gtagtcaagg aagatgacaa acttatactt attgttggtt gcagtcataa
     8761 tggaattgag aatattatag gcaaggtgga aaaatacttt tctaaaagca tctttgcagt
     8821 aattggtgga tttcatttaa aaaattttca acaagatgat tttaaagaac tctgtgagtt
     8881 tttcaagaat aagagaatct ataaacttgt acctcttcac tgctctggga cagaagcatt
     8941 aattcatttt ggtaataaaa tggcaaataa gctaaaagtt tgtggtgtgg gagatgtgat
     9001 tgaaatataa acattttaaa aaggtggcag tagcgcatga gaaaagattt ctgggaagat
     9061 aagatagtta ttattacagg ggtaacgtct ggtctgggga aggaaatgac aaagatttta
     9121 cttaaaaaag gtgcaaaggt tgttgccatt tcaaggtcaa aagagtcttt aaaagggctt
     9181 cagaatgagc tcattagttt ttcgaaaaat ctctttttga taaaggctga cgtgagcttc
     9241 agaaaagatt gtgaagatgc atttaagatc ataaaagata agctaaaaac ggcagatttc
     9301 ttaattaaca acgcaggagt tggcttgaga tgtgaagtgg aagaaataga ggatcttgat
     9361 cttaaaaggg tatttgatac taactttttt ggtgcatttt acatgatgaa gtatggaata
     9421 gcctttttca aagaactagg aggaggcaca attgtaaata tttgttcact tggtgtgaaa
     9481 agacctgtgc catttacagg tggatacaca gcatcaaagg cagcactttc aaccatagct
     9541 gatgttgcaa gaatggagct taaaaaatat aacataaata ttttaaatgc atatccaggt
     9601 tctattttaa caagctttag aaaaaaagct ttaggaaagc catatccaga agatgaagtc
     9661 cggctttcaa ggctttcgcc ggatgttgct gcaagaagaa ttatcagagg tatagagaaa
     9721 agcagaaaag agatctacac atctaaaaaa gactatatat ttgtgctttt tacccgcctt
     9781 tttccacaca tttcagattt tatcgttgaa aaggcatttg aaaagaggtt aaaaggatta
     9841 taattgcctt aacacctaaa ttccttgaca tgaataaaaa tacgtgctaa aatatttcaa
     9901 aatttaattt gaaaataaca aaaagctatt agcaaaaaac aaatgtccga caaactaaag
     9961 tagcacggtc ggacttttca tatataaagg gtgggttttg atgaagaata aaatgacggt
    10021 agcacgggca atggtagagg ttttaaggag cgaaggtgta gagattatct ttggcattcc
    10081 aggtgctgca atatatccgt tttatgatgc tctttatgac tctaacataa agcatgtcct
    10141 tgtgagaaca gaacaggcag cagttcatga ggcaagtggg tttgcgcgca caacaggtaa
    10201 agtgggtgtg tgcgttgcaa cctctggacc tggtgcgaca aatctgataa ctggtattgc
    10261 cactgcctat atggattctg ttccaatcgt tgcaataaca ggtcaggtga attcaagttt
    10321 aattggaagg gatgtattcc aagaagttga cataacgggg gcaacagctc cttttacaaa
    10381 acacaattat ttggtaaaag acccaaagaa gattgtaaag attttaaaag aggcatttta
    10441 tatagcttcg acaggacggc atggtcctgt tttaatagat gttccaatag atgtacagat
    10501 gcaggagatt gagtttgaac ttccaaaaga catagatatt ccgggctaca agccaaaaga
    10561 aaaaggacat cctcttcaga taaaaagggc tgttgaagca attgagaatt ctcaaagacc
    10621 agttatatgt agcggcggtg gcgtgattgc ttcgagagcc tcagatgagt taaaaatatt
    10681 ggttgaaaaa caaaaaatac ctgtaatttc aaccctaatg ggaattggct gtattcctac
    10741 agaccatcct tattatcttg gcatgatagg ctcacatggt cagaaagagg caaatttagc
    10801 gctcagacaa gcagaccttt taattgtgat aggtgcgcgg cttgcagaca gggcgctggg
    10861 tgatacaaaa gttactgaca atatgaaaat tattcatata gacattgatc ctgctgagat
    10921 aggaaaaaat gttgatacaa atgtgccaat tgttggcgat gcaaaacagg tgctttcaga
    10981 gattaataaa agaatttcag aaagaaaaga tttttgggct catgagatta aagcgcaaaa
    11041 gaaagttctt ccagatgatg acaagcttca tccttgtgat gtgctaagag aaatttcaag
    11101 ggcatacaat ggtgattata taatcacaac tgatgttggt cagcatcaga tttgggcggc
    11161 tcataatcta tatatcaaag aaccaggaac ctttataact tcgggtggac ttggcacaat
    11221 gggatatgga gttcctgcgg caattggtgc aaagtttgga agacctgata aggaggtaat
    11281 tagcatcacc ggcgatggaa gtttccaaat gcttttacag gagcttgcaa caataaaaag
    11341 agaacaagtg cccattaaaa ttgtcctttt caacaacaca aggcttggaa tggtatacga
    11401 acttcagaag aaaagatgca caggcaggtt tattgcaaca tgcttagatg gcaaccctga
    11461 ctttatgata ttggcaaagg cctatggaat tgagagtatg aggcttgaga gtaaggaaaa
    11521 gttaaaagaa gctattgaga ccatgaaaag ccacaagggt ccgtttttgc ttgaagttgt
    11581 gacaagtcct gacgagccaa ctatacctta agggtttaat tgagcttact aaaacttttg
    11641 gtgatagggg gatgtatgaa ggtgaagtac acactttctg ttttagttga gaaccacccg
    11701 ggtgtactgt ctagagttgc aggacttttt tcaagaagag gttttaatat agacagcctt
    11761 gctgttggtg ttacagaaga ccctacaata tcccgcatga caattgttgt aaatggagat
    11821 gactacattg tggagcaggt gacaaaacaa ctgaataaac ttattgatgt tataaaggtc
    11881 aaaaagctaa acccaaaaga agctgttgaa agagagcttg cgcttatcaa agtaaatgct
    11941 aattctcaga cacgttcaga cattattcaa ataacagaaa ttttcagagc aaacattgtg
    12001 gatgtgtcaa aagaaacact tacaattgag atttcaggtg atgaggacaa gattgaagca
    12061 ctaattgagc ttttaaaaca atatggcatt cgtgaggtag tccgtacagg acttattgcg
    12121 atagaacgag gaaacaaagt tatatcaaaa tctaagtctg aggaggatga ttagagatgg
    12181 caaagatatt ttatgatcaa gattgtaatc tagacctact taaagacaag acggttgcag
    12241 taattggttt tggcagccaa ggtcatgcac atgcactgaa cttgagagat tctggtataa
    12301 acgttgtggt tggactttat catggtagca agtcttgggc aaaggcagaa agtcatggtc
    12361 ttaaagttat gacagctgat gaggcaacaa aagctgcaga catcattatg attcttgtaa
    12421 atgatgaaaa acagccaaag ctatacaaag agagtataga gccaaattta aaagaaggaa
    12481 aggcaatagc atttgcacat gggtttaata ttcactttgg tcagatagta ccaccaccat
    12541 acgttgatgt tataatgata gctccaaaag gaccaggcca cacagtcaga agccagtatg
    12601 aagaaggaaa aggtgtacca gctttagttg ctgtacatca ggactataca ggaaaagcct
    12661 tggatattgc tttagcttat gcaaaaggta ttggtgcatc aagggctggg ataattctta
    12721 caacatttaa agaggagaca gagacagacc tttttggtga acaggcagtt ttgtgtggcg
    12781 gtcttacaga acttatcaaa gccgggtttg atacattggt tgaagcagga taccagccag
    12841 agattgcata ttttgagtgt ttgcatgaga tgaagctgat agttgatttg atttggcagg
    12901 gcggactttc tttaatgaga tactctatct ccgacacagc tgagtatggc gattacatga
    12961 caggtaagag aattataaca gaagagacaa gaaaagagat gaagaaagta ttagaagaga
    13021 ttcaaaacgg tacatttgct aagaagtgga ttttggagaa catggcagga agacctgagt
    13081 tcaatagtat aagaagaaga gaacaaaatc ttttgattga acaggttggt aaagagctta
    13141 gaaagatgat gccttggata aagccaataa aagaataagg gtgaggggtt tttaatggga
    13201 aaaagagtta taaagatatt tgataccacg ctcagagatg gtgaacaaac accgggtgtg
    13261 tcgctcaacg tcaatgaaaa acttgagatt gcaaaacagc ttgaaaagct caaagttgat
    13321 gtgatagaag cagggtttgc aatagcctct cctggcgatt ttgaggctat aaagacaatt
    13381 tctgaaaaca tcaaagatgc agttgttgta tctctggcaa gagcaattga aaaagatata
    13441 gatagggcgt atgaggcgct caaaaaggct tcatccccaa gaattcatac attcattgca
    13501 acaagtgata ttcatatgaa atacaagctc aagatgacag aagatgaggt actcgagcga
    13561 gcagttgcca tggtaaagta tgcaaaaaaa tatgtgtctg atgtagagtt ttcatgtgag
    13621 gatgcaacac gttcaaggat tgagtttttg ataaaggtgt ttgatgctgt aataaaggct
    13681 ggtgcaacag ttataaacat accagacacg gtaggctaca caacacctga agagatgaaa
    13741 aggattattc gagcattaaa agaaaacatt cctgacattg acaaggttca aatttcagtt
    13801 cactgccaca atgacttagg tcttgctgtt gcaaactcac ttgcagcggt agaagaaggt
    13861 gttcatcagg ttgaatgtac aataaacgga cttggagaaa gagctgggaa tgctgcttta
    13921 gaagagattg taatggctct caagacaaga aaagactttt acgatgttga tgtattaatt
    13981 gatacaaccc aaatttatag aacaagcaag ctcgtatcct ctttaacggg cgtgtttgtt
    14041 cagccaaaca aagcaatagt tggtgcaaat gcatttgcgc atgagtctgg tatacatcag
    14101 catggagtat tgtcagaacg aacaacatat gagattattg accctgtatc aattggtctt
    14161 cctaaaaaca ggatggtttt gggcaagcac tcaggtcgac atgcatttga agaaaggctc
    14221 aaagaacttg gatacacaga ccttacaaga gaagagattg atgctgcatt tgaaaagttt
    14281 aaagttttgg cagacaaaaa gaaggttgta cttgacaaag acatagaagc actcttagag
    14341 cagaagtctc tcaacatccc agagacatac gagcttgtta agttccagat tataagtgga
    14401 aatgatttaa tctcaacagc atctgtcaag ataaaatcag gtgaagaaga gtatgaagag
    14461 gcggcaacag gcgatggtcc agttgatgca atcttcaaag caattgatag aatcacaggt
    14521 cttcaggttg aacttgatga ttatagtata aaggctgtta cccaagggaa agacgctctt
    14581 ggcgaggtaa cagtcagaat caagaaggat ggcaaagcgt ttttgggaag aggcttatct
    14641 acagatattt tagaagcaag cgcaaaagcg tatgtaaatg ctataaataa gatgctgtat
    14701 aaaatttcag aggagtaaaa ttgactcttt acaatttttt aaattgggtt taaaataatt
    14761 agcaaataaa acttgagggt caaaggggtg caaaagatga taatacgaat atgcggcgca
    14821 atcacaataa ttagcattat ttcaataatt agaaagagaa taattaagtg gatttataaa
    14881 atttcatatg ccgcattgca cccattttgg cctgtgtatg agcaaagagg gtttttgaaa
    14941 agacccttag ggcatcttta gaatttgcaa tcaaatttga gattgaattt taaaagccca
    15001 gcctaaaaaa tcacaggctg ggcttttttg atattaaaaa ggagggaaaa tgaagtggaa
    15061 gataataaga ccatcatcat ctatgactca accttaagag acggtgctca ggctggggga
    15121 atttcatata ctttggaaga taagctcaag attgtagaga ggcttgacaa atttggtgtg
    15181 aaatttatcg aagcaggcaa tcccggctct aacatcaagg accaggagtt ttttgcaaga
    15241 gttaaaaaga tgaaattgaa aaatgcaaag cttatagctt ttggttcgac aagacgagtg
    15301 ggaattgacg tgaaagatga tattaacatt cagtcactaa ttgcagctaa taccgaagct
    15361 gttgcaatct ttggcaaatc gtgggatttt catgtcaaag aggtcttaaa aacaacagag
    15421 gacgaaaatc ttcaaatgat ttatgacaca ataaaatatt taaagtcctt gggcaagtat
    15481 gttgtatttg acgcagagca cttttttgat gggtataaga ataacagaaa atacgctttg
    15541 gagactttaa aggttgcaaa agaggcaggt gcagactctt tagacctgtg cgatacaaat
    15601 ggtggtactt ttccaatgga tatttacaac ataacaaaag aagttgttga gatgtttcct
    15661 gggacattaa ttggtattca ctgtcacaac gatacaggta tggctgttgc aaactcaatc
    15721 atggcagttt tggcaggagc acgtcaggta cagggaacta taaacggata tggtgagaga
    15781 tgtggaaatg cagaccttat cacgctcatt ccaaatcttc agctaaagct tggatttaaa
    15841 tgtgtaccag atgagaacat aaaacacctg acatctcttt caaggtatgt tgcagaaata
    15901 gcaaacatga ttccaaacga aagagcacca tatgttggag cgtatgcgtt tactcacaag
    15961 gctggtatgc atattgatgc agtcaagaaa aatccagcat cttttgagca tgttaaccct
    16021 gaaattgttg gaaacacaag aagaatagta ctgtctgagg ttgcaggaag atctacaatt
    16081 cttgacaaga ttcgcgaaat tgacccgaca gttacaaaag actcacctgt gacaaaagag
    16141 attattgatg agctaaaacg tcttgaaaac gaaggatatc agtttgaatc tgcagaggct
    16201 tcatttgaga tgttaattag gaaaaagctg gggctttatc agccgttctt tactctaaaa
    16261 gaatttaaag ttctcattaa tgaaccggca gtagagtaca gctcatctgc aattgtcaag
    16321 attgcagtag atggtgtcac agcaatcaca gcagcagaag gtgatggtcc tgttcatgct
    16381 ttagataatg ctttgagaaa agctttggaa aagttctatc ctgagctcaa agaggttcat
    16441 cttgttgact acaaagtaag agtgctcaac gccgagacag caactgctgc aaaggtaagg
    16501 gttctgattg agtcaacaga cggaaaagac acatggacaa ctgtaggtgt ttcaacagac
    16561 attgtaaatg caagctggat tgcacttgtg gattcgcttg agtataaact ctgcaaagaa
    16621 aaagtgggga aataaataaa gtggggctgt caaatttttg acagccctta tctacatttt
    16681 gtatcagatg caagtaattt cataaactaa tattcaaaat attgagcagt tcttcatcta
    16741 atttttttga gagttatgct taccagcata aaaacttgag ctattaagta agttttttca
    16801 tttttattga taataagctg taattatata atttgtccat tcgtcatgta tttctttatc
    16861 tgacttctga aaaatttccc tatagttgtt atacattaac aataataata ccttgtgcca
    16921 accatatttt ctgtctatgt attcaatgta agtatctgca agaatatacc cgcccatatt
    16981 tgtaaatttg attgggtttt ctgtttggat gtcttcaaat aaaggaattt ttatgttttt
    17041 taattctcct tttttaaact gtccaccgtt ggttaaatat aaggcaatac cttaatttag
    17101 ccatttttta atttttggat tgattaaata ttcataggca tgatccattt catgcagaag
    17161 tggttgttta acactttcag agttgtgtaa ttttcctgga tttgaaggtg aggttaatat
    17221 aactgttgaa cctaagttgt cgccgatata ccaatcaagg ttaaaaagaa gagttattaa
    17281 tccatatctt ttagtttgga acgtggatcg tttgtcataa ataaatattt ttattttaga
    17341 tttttcttta atacctaatt tgcccataag atattatgct ctctgttctg ctaaattaaa
    17401 acaatctaaa gcagctattt cttctttttc gtaatataca tcaacccact ttcctatttt
    17461 taccttcata ttttttgttt ttagttgtga tgttggtata aacgtggaac caaaagctat
    17521 tatgaggaat aataatcaaa atagagattg ttttaattac tttgcttttt tcatgtagtg
    17581 cctggtcaac taaactgtgc aaaactgcat agtttagttg acaaggttga gtgttttaca
    17641 cgtgaaaggc tcaaaactat tgagaataaa actgattctt cgtacgttgt ggactggtgc
    17701 ttagataaaa cgggggaatt tatacattgt agctatgaat aatacaaaaa aagatatgca
    17761 gtttttagta ataaaagggt acaacgccaa aaataacaag atattcttaa gctcaagaaa
    17821 tgtcaggtta aaaccgcaga ctattgacac aaaagttatt tcaggtgtgc ctacttattt
    17881 aaaaaatgtt caggttgaaa ttgtacaaag caaatctgtg ccttcatttg ttgttgactg
    17941 gtattttaac aagcaaggta gtttgtatat agttggcata aataattctg aaagagatga
    18001 taacctgttg gtaaaggtag aagcctgtga ccaaaaaggt cagaaaattt gggttgggtt
    18061 cgagaaactt tagagtccta aaagtaacaa ttgacacttg tattgtaaat aatattcctg
    18121 catatgttaa aaaagttaat gtatcagttt tgcctgagca ggatggtgtt aagactcagg
    18181 aaaagttatt cgacagagag cgaacaaata ttgtatatta ttattacaaa ttatgaaaat
    18241 gacaaaaaca taaaaattca agtaaatggt tttgacgcaa atggcaggct tgtgtacaaa
    18301 agtatatata atgcagatgc aaaaagtaat attgttgaag cgcatacgat taacatatcg
    18361 aatagcaaga tagaaagagt agaaataaat gtaaaataaa aaacagggga ccatttttaa
    18421 aaatgctctt tttcggtccc cagttattag ttttcggtat ttttatattt gtaaaccatc
    18481 aactattaat atggtctcat aaacatctgt gtccaataca aaactccatt actctttttt
    18541 gcaaccccaa caccaatctc agtaaaagaa ggacttagta tatttgccct gtgaccaggg
    18601 gaagacatcc atgctcttac aacttcctga gcactccttt gcccatatgc aatattttca
    18661 ccagcagcca tgaactttag tccaaaattt tccatcattt taaaaggtga accgtaagta
    18721 ggagagtagt gcgaaaaata gtttttgttt gccatgtctt gagatttgaa ccttgctacg
    18781 cgacaaagct gccagtttgt cttcaaagca gaaagtccta cctttgccct ctcttgattt
    18841 gtcagtttaa ttacttcatt ttctaagaca tttaaattgt tgctatttgg aatatttatc
    18901 ttttgcccag ggtatatgag gttaggattt ttaatttgag gatttgcttt caaaagttcg
    18961 cttattccaa tttggttttt aacagcaata ctccagatag tatcccctgc ttgaactgta
    19021 taagtttttg tttgtgcaaa tgctgttgaa aatgataaaa gagctataat gcttaaaact
    19081 gctaatgctt ttctcataaa cttcacctcc ccatttatta gtttcttaaa ttgtttgtaa
    19141 aaatataagc aaagatttgc taattccaag gtacgtaatt caattttcta aattgcaata
    19201 ttaatgcaac acttttttaa aatgaaccga aaattgtaat ttgattaaga cgacaaactg
    19261 tgtatgataa tagttgcgaa tatatgcatg ttttcctgaa ggaaagaaga aagctgtcat
    19321 tttgtgttat atattctcct atttagatgg tatctcctat acctcctgca aaaacttctc
    19381 taatgtatct gcttcacata ttcccttcat ttcctctaaa aacttttcta tgctactttt
    19441 gtagttaaac atccttttgg gaagtctatt gcaaatgtct tcaactcctc tttatagctt
    19501 ctttcgatat tttgcttatt tctttccttt tgggtaaaaa acaccttatc aactctattt
    19561 gcccgctcgt ttgttcccct ctcatatgtg aatatgggtg tgtataatat ccttccgacc
    19621 ctaattcatt taagactttt ccaagcctac ttgcttcact accattgtcg cttgttacac
    19681 ttttgaacac tctattgaat ttctctccca tcttatcttt gctaaatcca agcttttgcc
    19741 tacaatattc aacaactgta ataacattcc atttatcttt cagtatcttt tattctacaa
    19801 actccaaaaa tttttccacc tctaaaagtt tatttttcct gttacacttt acttcttaat
    19861 ctctcataca caactttacc tgtttgggca aagtattttt caaatgttac ttgtgtcagt
    19921 ttctcatttg agtgattatt ctttgtttta cttcatgtaa aattgtactt gcacttttat
    19981 gaagctcctt tgttatctct tttatgccat atcccatttt taatagcttt tctataattt
    20041 ttctttctgc ttaacttagg tgtttaaatc ttcttctctt tgtggtatga ttatcatagg
    20101 tcataacttc aaacctcctg tgtatggttt tgtcttttta tactgctatc atacacagtt
    20161 tgaagctatg gcttcaatat ttcttacctt gttgcattta attttacaac aaacatataa
    20221 aaagtttttg tttaaaatac ttgacaatta taattaacaa gtgtaaaata aaaacataaa
    20281 ctacacatgt aaaaattaaa aaggagtata caaaaattat gaaagaaaaa tcatttccaa
    20341 agatttcgaa agcagagtta gaggtaatga aagtggtatg gaaagaaaat agagttttga
    20401 gtggcaggga gattgtaaca aaagtgatgg agacaaacaa gaagtggcat aagaatacca
    20461 tattcacttt aattgatcgc ttagctaaaa aaggtgttct aaaagtagaa aagaaaggga
    20521 agttcaattt ttacacggca agtataactg aggaggacta taaaaaggaa gaagcaagag
    20581 atattttaca gaggatgttt ggtgggtctt ttagaaatgt aattgcaact tttttggaaa
    20641 ctactaatgt gagtaaaaaa gagatagaag agataaagaa gatgttagat gagaagggat
    20701 gctgcaagta tgataatgga agtttttaaa tgggtaatgg gaatgtcgag acttgtcgag
    20761 aattttgtat atccaattca tagcgtaatt tgaagagttg taagatttcg taagtatggt
    20821 gtttgataag aggtattcca tttttccatt tacctcgctt aaagttctct ctttgaagat
    20881 aaatattaat ctcaagaacc tctggtactt gaaaatatcc gccagatttc atttttatct
    20941 ttctcaatta tactatttat gctctctact gcgttagttg tgtaaatgag ctttctaatt
    21001 cttttcggga tatcttatgt gagcagagta atacttagct ttttctaaaa gtccttttaa
    21061 aaagcgagga tatttaggaa ggtattattg caaagctgac taaatgcacc gacagtttca
    21121 tcaacatcaa aagaagagaa tcttatttta tctaattctt tattaaattt tgaactatct
    21181 tcttttgtca tatctcgttt tacattacgt tgcaggtggg caaaagcaaa cttaaggtca
    21241 gctcaagagc aagcgatttt gacagcatct atttattgat agggaagtca tcgcttacaa
    21301 ttattaagac ttttttaaga cctcttgttg attaaatctt taaagacttt catcctatca
    21361 actttgtttt ctttgccaaa gaaggtgtaa atgccgaaga tatctttttt gctgtctaaa
    21421 atcgatgccg agaacgatgt agcaggtagc ctgtttaacc tttgagttgt ccctaatttc
    21481 acatctgaat agctatcaat tggaagtatc aaggcatttt ccggtagttc cccttattta
    21541 aagagctgga attcgtttct aaggtcattt ttggttttag ctactacctc ttctgagtaa
    21601 agtaagtcac ggtttttaag ggtttggatt agcaaacttt cagagtagct gttagcaacc
    21661 aaagacataa gtaaatcggt gtaagatgaa ttgactcttt tatatgactg tggtaagaca
    21721 gagggataga gtaaaggcaa agattaaaaa gtcaaatcac ttttcaaaga tttcagaagg
    21781 tattgccatt gtagaggatg ataaaggttt aaagggtttt tatgtattta gttcagacaa
    21841 aaaattagat gtagataatg caaaaacaga aaggtggtat ttaaaaaatc tcaaattgtt
    21901 tcaataactt taatagtgtc attttgaaaa gaatatacaa ttttttacaa aaaaggctgc
    21961 aagaagaatt tttctcttgc agccgaattt ttaagctctg attttaattg agttttacct
    22021 ttccaccttt ggcatgggcg ataagattga agggttattt gcccttgctc ttatcaaaat
    22081 tgcctcaagt aagcctctat ttttgtgtgg cttttctgtg catgcgatta tatcctcatg
    22141 tggcaggtta ttaattctgt cattcattgc ttttatcgca tcaatcgagt ttataacagc
    22201 tcgttcaact ggcattctct ctggatttat gtcaattcca aaatatcccc tgtaaccata
    22261 catcttcatg acataaagtg ctgcttctgc ctgttcaggt gagataacac cgacgtttaa
    22321 atcttggtca taatttccaa gtggttggct gttccagtgt gtatgataga gctttccata
    22381 ctcaagtgca agtgaaaatg catacgccaa atcctcaaat cccatcaaaa catgtccaac
    22441 ttcaggatta agaccaacta aagagtcatc ctctaaaatc tttttatttt cagggttttg
    22501 cagcagtttt tcaacctttt gtgcaagaag tataccttcg ccagtcagcc cgtaaattat
    22561 tcttcctctt ggctcatatg gttttggctc aattgcaacc tttacacctg gcacagcatc
    22621 cattgcttca gcaatacctt cagcaaacct gtctctcatt cttataaagt caattccaaa
    22681 ttggttttcg tatccatctc cacctggcca gataatacag aattcacagt caagctcttt
    22741 gtttagcatc aaagacgttt taagtctctc gatagccttt tttcttactt cttcaatggg
    22801 tgaggcgagt gatgaaaatt cgaaatcgtt ttcataaaac aaattaggaa ttactgataa
    22861 aatctttatt cctgtatctc ttgaaaactt tttgtaaagc tctaagttgt cttcgttaat
    22921 ttcgtttgga taatgagcct ctaaagcgca aactccatag tctttaagct ttgctatgat
    22981 ttcaagtctt tcttcaattg tttttggttc gccaagtggt gcatggaatc tgcttggatg
    23041 gtctgaaaaa taccagatac caacagaaaa tttaaggtca agctcaaatg tcttaaggtg
    23101 ctgaatcagc tcatcaacgc ttcttctttt catctgatag cttgtgtttt caagcatact
    23161 caaaaacctc ctttaatc
//
