LOCUS       NC_014387.1            25333 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_014387.1 Butyrivibrio proteoclasticus B316 chromosome 1, complete
            sequence.
ACCESSION   NC_014387
VERSION     NC_014387.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:32:47
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1512148
            Orig. end    :: 1537481
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25333
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1522148:1527481]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15333
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..25333
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25333
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="3"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             362..1456
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PduV-EutP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1208"
                     /sec_met_domain="PduV-EutP (E-value: 3.7e-07, bitscore:
                     27.5, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDNFKTGFITLIGRPNVGKSTLMNHMIGQKIAITSNKPQTTRNK
                     IMTVYTDDDCQMIFLDTPGIHDSKNKLGEYMTKVAKSTLEEVDVVLWLVEPSTFIGAGE
                     KSIIEELKKCRKPVILVINKIDTVSKDNLDKFENAYRQEMDFDRVVKVAALKGQNIDEL
                     MDAIKKLLPFGPPFYDEETLTDQPERQIAAEIIREKALRLLQDEVPHGIAVTIETMRMR
                     EKVVETPRPKKKRHQHPPKKSKLEAMEKELSSALDNPEDLDEDFDGPMVLDLSAIQEPE
                     QDYDPDGIMDIDATIICERDSHKGIVIGKGGAMLKKIGSAARKDIEELVGCQVNLQIWV
                     KVRKDWRDDKTQMKSFGYDIRDLK"
     CDS             1519..2172
                     /locus_tag="ctg1_1209"
                     /transl_table=11
                     /translation="MEDFVVVRGIVLKHAPVGDYDWVATIFTAERGKITAFARSARKPS
                     AKLSGLVEPFCFGTFKLFAGKNSYTIAEADIENYFEGFRADLEGACYGTFFLELCSFYT
                     RENNEDKDLLNLLYFSLKALLKENIPNRLVRCIFELRALVIEGEYPGIPEGQKLLDSTR
                     YAMGFITTSPLNKLFSFSLSEEVLGELDRITKEYRNTYIDRPLKSLEMLEIFEY"
     CDS             2238..2864
                     /locus_tag="ctg1_1210"
                     /transl_table=11
                     /translation="VKIHSFKENKSLYASAISFAILTFIGVTSLTGCGGDNRRDTNLSI
                     SKDGRITNTIYEAFDRDYYDIDELSDMANREISYYNSEYDKPRIAISDVGVIEDDTIGK
                     IVMTFETSSDYSHFNQTSLFYGTVQEAIDNGFELSGSLVDKNGNVFDLGYEDYLNKHIV
                     ITGEKTVIYTPYNIEYMTSGVELLDKKEADLTNVTTDLVQILLSK"
     CDS             2917..4326
                     /locus_tag="ctg1_1211"
                     /transl_table=11
                     /translation="MEANAKTMDKIVALAKARGFVYPGSEIYGGLANTWDYGNLGVEFK
                     NNVKKAWWQKFVQENPYNVGVDCAILMNPQTWIASGHLGGFSDPLMDCKECHERFRADK
                     IIEDFAAENNITLETSVDGWSHEEMENFIKEHSVPCPSCGKHNFTGIREFNLMFKTFQG
                     VTEDAKDTVYLRPETAQGIFVNFKNVQRTSRKKVPFGICQIGKSFRNEITPGNFTFRTR
                     EFEQMELEFFCKPGTQTEWFEYWRKTCYEWLLSLGIKKENLRLRDHDPEELSFYSDHTT
                     DIEYAFPFTDWGELWGIASRTDYDLTRHQETSGQPMDYFDDETNEKYIPYVVEPSLGAD
                     RVTLAFLCEAYDEENIGTEEKPDMRTVLHFHPALAPVKIGILPLSKKLNEGAEKIYAKL
                     SKKYNCEFDDRGNIGKRYRRQDEIGTPFCITYDFESENDNMVTVRFRDSMEQERIAIDE
                     LEAFFSDKFDF"
     CDS             4405..7059
                     /locus_tag="ctg1_1212"
                     /transl_table=11
                     /translation="MKQFTAQELREAWKQFYKDRGHVDCGAVSLVSDGSTGVMFNVAGM
                     QPLMPYLLGKKHPMGTRLCNVQGCVRTNDIDSVGDKSHGTFFEMMGSWSLGDYFKKERC
                     QWSFELLTQLFGFDADHLAATVFAGDENAPRDEEGAKYRIESGFKPENIYYLPAEDNWW
                     GLEYGPCGPDSEMFYVKDMPDCGPNCGPGCHCGKYTEIGNDVFMQYEKHHDGHLTPLTQ
                     KNVDTGWGLERILAFLNGVDDVYKIDLHAPVIAYIEKESGLKYESDEKTTRSMRILADH
                     TRTSVMLIGDEAKLLPSNTGAGYILRRLIRRAVRHARTLGLNKDQILGVATIYIDEYSE
                     SYENLAKNRKFVLTELEREITRFESTLENGMKEFRKILDKTSAAGKKEIEGKDAFFLYD
                     TFGFPVELTVELADEEGFTVDEEGFKASMEEQKQKARENQNFSANLSTGTGLFDNLDES
                     VATEFLGYEKLECDGTVAVIAGADALVTELTEGQQGTIITDKTTFYGTMGGQVGDIGEI
                     LGSNGAKFEVTEAVKVAGGRTAHVGKVVSGSFKVSDKVTLSVDAENRAKTCRNHSATHL
                     LQKALQMVLGDGVEQAGSYQDPDKTRFDFSYHQAMTADEIKKVEDIVNSKILEALPVVT
                     KEMSIEDAKKTGAMALFGEKYGETVRVVNMGDFSIELCGGTHVANTSHIGLFKILSESG
                     VAAGVRRIEALTGDNARAYYKNVEANLGEAAKTLKTTPADLVDHIKKLQEELKNLRSEN
                     ESLKSKEAQAALGDVMDQVLEIKGVKLLATSVKGVDMNGLRDLGDQMKTKLGEGVVVLI
                     SEADGKVNLVTMATDGAMAKGAHAGNLVKAIAPKVGGGGGGRPNMAQAGGKNPAGIQDA
                     LAEAKTVLLSQIN"
     CDS             7213..7389
                     /locus_tag="ctg1_1213"
                     /transl_table=11
                     /translation="MSTVVVKENETLDSALRRFKRSCAKAGIQQEIRKREHYEKPSVRR
                     KKKSEAARKRKYN"
     CDS             7537..8406
                     /locus_tag="ctg1_1214"
                     /transl_table=11
                     /translation="MWIYILIAILILIILSVIVIYHDTHNFVVRRYDVYSDKIEGDYTF
                     ALLSDLHGYVYGNNNDRLIEAVTRENPDAVLCAGDMFTGHKIKGEIRYQAGFHVLTELA
                     GEFPVYMANGNHEHKIKTYTVEFGNLYSRYRSGLQKAGVVVLENDSVDIQGTNIRITGL
                     ELKHDYFRKVIKLEMEKGYVDKTVGHSSKNKFQVLIAHNPQYFDEYADWGADLTVSGHV
                     HGGIIRLPLLGGVISPAIALFPKYDGGKFTKDGKTMILSRGLGTHSIHVRMFNPGEVDI
                     IRVHSVNK"
     CDS             8446..9195
                     /locus_tag="ctg1_1215"
                     /transl_table=11
                     /translation="MSLEVKLQVFEGPLDLLLHLIDKNQIDIYDIPIATITDQYLEYIN
                     AMQSDDMDVTSEFLVMAATLIDIKCKMLLPKEVNEEGEEEDPRAELVEKLLEYKMYKYM
                     AYELKDRQMDAGLSWFRNKNIPQEVKDYEMPVDLSELIGDATLSKLNEIFQDLLKRQED
                     KVDPIRSKFGNIEKEEVDMDAKTLYIRAFIREHSRFSFRQLLEKQHSKTEIIVTFLVML
                     EEMKLGEIEIEQETTFGDIIITSRKAS"
     CDS             9197..9766
                     /locus_tag="ctg1_1216"
                     /transl_table=11
                     /translation="MTREEGAAVVEAILFTMGDSVEISALAKAMEMDAREIKKYIDYLK
                     EKYERSDSGIGIIELEKAVQLCTKKEMYEYLVKIAKAPKKAVLTDSLMETLSIIAYKQP
                     ITRLEVEKIRGVNSDHAVNRLVEFGLVQELGRLDAPGRPLLFGTTEEFLRSFGVRSLDE
                     LPSIGTVQVEEFKAQAEEEINVKLDI"
     CDS             10001..11431
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1217"
                     /sec_met_domain="CT_Vparvula (E-value: 1.1e-128, bitscore:
                     427.5, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSSSQARQRINALLEENSFVEIGALVTARNTDFNLKQEETPSDG
                     VVTGYGVIDGNLVYVYSQDASVLGGSIGEMHARKIVRLYELAIKTGSPVIGLIDSTGLR
                     LQEATDALNGFGEIYLKQVEASGVVPQITAIFGACGGGLAIIPSITDFTFMESEKAKLF
                     VNSPNALDGNYKEKCDTSAAKWQSTETANVDVVSDEASIYAQIRELVSILPSNNEDGDS
                     YQECSDDLNRACENLDGATADPSLIARQISDNGLFFETKREYAKEMVTGFIRLNGATVG
                     LVGNRTAVFDENGKEAEKFADKLTAHGLEKAAEFITFCDAFDLPVLTLTNATGFGTSKC
                     DEKHVAKAAGRLVYSLANATVPKVNLITGKAFGSAYVIMNSKAIGADVTISWPDAQVGT
                     MDANLAAKIICDGKDAETVSKAAAEYAALQNNVKSAAARGYVDEIVEPADTRKYVVGAF
                     EMLFTKRDERPAKKHGTV"
     CDS             11449..12276
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1218"
                     /sec_met_domain="OAD_gamma (E-value: 3.3e-20, bitscore:
                     70.0, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHKTLVLGVMLSCLLGLTACGAEVKSNTVEGSRYSSDIFTQESL
                     KGFAESLEDNNFEGWYLQGITPDNFESNLYFDIALNSTDERYEVLASGYDSWYKALDDL
                     GYNSVETLANDIFVKEVNYEVNKDDELVVNAVLQGTKHTADMEIYLTNRGEVTDIGVTV
                     NKTTAEKLENAGLNTLLGMGMAFTILILISLIISLFPMLFGGNKKKKESDKEITQKAMD
                     NTINQIAEQEDLSSDAELVAVIAAAIAAYEGSAGTDGFRVRSIRKVNNNWKKH"
     CDS             12327..12686
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 60.4; E-value:
                     3.7e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1219"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.8e-17, bitscore:
                     60.4, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNYTITVNGNVYDVTVEEGAGSGVAPVAAAPAVKAPAAPVKKAS
                     AGAGSIKVEAGAAGKVLKINASVGQAVKKGDTVVTIESMKMEIPMVAPSDGTVASIDVA
                     AGDSVEAGTCLATLN"
     CDS             12739..13881
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1220"
                     /sec_met_domain="OAD_beta (E-value: 2.8e-153, bitscore:
                     507.4, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYIVNTLSNLWQQTAFTTMTPGNYVMVVVALVFMYLAIAKGFEP
                     LLLVPISFGMLLVNIYPEIMAKPVGDSAGGLLHYFYILDEWAILPSLIFLGVGAMTDFG
                     PLIANPISFLMGAGAQFGIFSAYFMAIAFGFNDQQAAAVSIIGGADGPTSIFLASKLHQ
                     TSILGPIAVAAYSYMALVPMIQPPIMKLLTTDKERKIRMQQLREVSKLEKILFPIIVTI
                     VVSLILPTTAPLIGMLMLGNLFRESGVVRQLQETASNALMYIVVILLGTSVGATTSAEA
                     FLNTTTIIIVVLGLIAFAFGTAAGCLLGKLLCLVTGGKINPLIGSAGVSAVPMAARVSQ
                     KVGAEYDPSNFLLMHAMGPNVAGVIGTAVVAGTFMAVFGV"
     CDS             13921..15333
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: PYC_OADA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1221"
                     /sec_met_domain="HMGL-like (E-value: 3.6e-40, bitscore:
                     135.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 9.2e-56, bitscore:
                     186.2, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADIQKKPVRINETVLRDAHQSLIATRMPTEVMLPIIETMDQVGY
                     NAVECWGGATFDSCMRFLKEDPWERLRKLRAGFKNTKLQMLLRGQNILGYKHYPDDVVE
                     YFVQKSIANGIDIIRIFDCLNDLRNLEASVKACKKEGGHAQIALAYTLGDAYTEEYWMN
                     IAKDIESMGADSICIKDMAGLLLPYEAEKLVKALKSATSLPIDLHTHYTSGVASMTYMK
                     AAEAGVDIIDCAISPFALGTSQPATEVMVEAFKGQPFETGLDQKLLAKIADHFRPYREE
                     CLASGLMDPKVLGVNIKTLMYQVPGGMLSNMVSQLKEQNASDKYDTVLEEIPQVRKDFG
                     EPPLVTPSSQIVGTQAVMNVLMGERYKVATDQTKDLLAGEYGKTIKPFNPEVQKKIIGD
                     REVITCRPADRLEPGLAKFEKEVAQWKQQDEDVLSYALFPQVATDFFKYRMAQQTSVDV
                     SAADTKNGAYPV"
     CDS             15871..17265
                     /locus_tag="ctg1_1222"
                     /transl_table=11
                     /translation="MAENIDNNGCSQRDSAEHEGYAKALRSFNRIWKERDSAQPKLLEA
                     ILYKDNFNRAYKRVKANKGAPGIDGMTIEEALPYLKEHQQELTDRIYRGKYTPSPVRRV
                     EIPKPDGGVRKLGIPTVIDRTLQQAITQQLVPIYEPLFADGSYGYRPNRSAKDAIQKVK
                     EYAEQGYTFAVVLDLSKYFDTLNHEILINLLRKNVKDERVVQLIKRYLKSGVMENGVVI
                     DTEEGSPQGGNLSPLLANIYLNEFDQEFLKRGVPCIRYADDIVLLAKSKRASERLLESS
                     TKYLEEKLKLTVNREKSRTVSAFAIRNFKFLGFALGRNGSGIYVRVHPKSWKKFKSKLK
                     DLSSRKSVQSIKPSLEKIKTYTRGWLNYYGIASMKNNIDDINKWLYHRIRMCIWKQWKL
                     PKTKKRNLIKLGIPEYYAHITANSRRGHWFVSGMGAVNCALSKERLINSGFYDLATAYQ
                     SVHVNY"
     CDS             17398..19575
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1223"
                     /sec_met_domain="Alpha-amylase (E-value: 5e-15, bitscore:
                     53.3, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEYRRHRQSRKPIEIGERQGRELRKSDLNRQMLALDEISGFRVR
                     PGFYGINGATMLTDGVNFTVYSNGATTVTLLLYHRGEDKPFAQIPFPESYKIGKVYSMI
                     VFGLDIENLEYCYSVDGPWDPEKGLLFNKNNVLLDPYAKAVSGQRIWGQRLNKNGQYRA
                     RVVRDNFEWNATSNLGIPMCDSVIYEMHVRGFTMDPSSGVKCRGTFEGIKEKVEYLKRL
                     GVTAVELMPIFEFDETRDKREVNGKVLLDYWGYNTISFFAPNTSYASQSEYNKEGVELK
                     HMIKELKDNGIEVILDVVFNHTAEGNENGPFISFKGFDNNIYYLLTPMGQYYNFSGCGN
                     TMNCNHPMVQELIVECLRYWVEQYRVDGFRFDLASILGRDQDGSPMERPPLIQRLAYDP
                     ILGNVKLIAEAWDAGGMYQVGNFPAWKRWAEWNGKYRDDIRSFLKGDIWAAPEAVKRIT
                     GSMDLYGGAYLGYESSVNFITCHDGFTLYDLYAYNSKHNEDNGWNNTDGANDNRSWNCG
                     AEGMTTDQGINDLRFRMMRNAITVLMCSRGTPMIYAGDEFGNTQYGNNNAYCQDNEISW
                     LNWQLLDKNKDFFDFYRRVIQFRRKHPCIRKDLPNAKSGYPNISLHTENPDNGNITGES
                     KVVCVRYAGFYNKKGHDDIVYMAINAYWEDVQIMLPNPPEGMYWALCIDTGDDDGKYFF
                     NRPKPLTWRNKTLKARSVSVFIAANGAEYGG"
     CDS             19565..20191
                     /locus_tag="ctg1_1224"
                     /transl_table=11
                     /translation="MAADDKSNADNFIVDGFQFMSESDTQKASLDSSKIKLLQSRVKSS
                     KPTDIKAVYEKAIENKIFKTPIGWGYLTGLRRKLLESGYADADLIPIPIDVSFSKHSAL
                     DNLSVKQRIKPQKQEKKLDFLKILSIICNIVLVILVILLFVIAATAESDNIINYKSNVT
                     NRYASWEQDLKEREKKVREAEKRLGITDTSSYYEDTEIIDDNQED"
     CDS             20196..20873
                     /locus_tag="ctg1_1225"
                     /transl_table=11
                     /translation="MEDLKILVVDDESRMRKLVKDFLVKDGYLVVEAEDGQQALDIFYE
                     DKDISLIILDVMMPKRDGWEVCKEIRTNSKVPIIMLTAKAEERDELLGFELGVDEYISK
                     PFSPKILAARVSAILRRTNQAANNQIMEIGGIVVNKVAHSVLVDGKEIDLSYKEFELLS
                     FFFENKGVALSREKILNNVWNYDYFGDARTIDTHVKKLRGKLGKKGDMIKTIWGMGYKF
                     DAE"
     CDS             20900..22408
                     /locus_tag="ctg1_1226"
                     /transl_table=11
                     /translation="MGNDKKFNKTHSIRFEMSIAFIATMIGTFTFCLVINLLFMENFYV
                     QNKREAIIEAYRSIDRATSTGDITSEEFDQEIRHICERYDIEMLVLDGDSKTVKSSTSN
                     AELLAQILWENMISPAGGEYEIENRVVLDVGENYTLQRDEDRYGRKYLEMWGVVGNGNL
                     VLVRSAMESIHDSVAISNTFMIYVAIVAIVAGSIVILYISKKITDPIKRLYFISDDMKK
                     LNFEAKYESTGDYHSEIDALGSNMNELSETLEKTIKELKNANIALKHDIAKKEEIDEMR
                     KEFLSNVSHELKTPIALIQGYAEGLKEGISDDEESRNFYCEVIMDEANKMNIMVKKLLT
                     LNQLEFGNESANMDRFDIVEMITNYIKSADLLARQKDVTIKFDEYEPIFVWGDEFKIEE
                     VLQNYYSNALNHIDGEKIIEIKLTRKDSHVRVSVFNTGKPIPDDSIGHIWEKFYKVDKA
                     RTIEYGGSGVGLSIVKAIMEGMHQEYGVKNYDNGVEFYFELETK"
     CDS             22432..23328
                     /locus_tag="ctg1_1227"
                     /transl_table=11
                     /translation="MRTKKYFGILTAICFSLCLAGCGEAFPELTDDEYNQTVEFAVGLL
                     MKYSNNGQAKLTYVDAKEVTKQREKEAALAEKEKDKETSKPAPQPVQEPVKVPEPIQTE
                     IEEPSMSSTEDLSLDDQGSTQIIDSAIDASSEEVVKEPDDTTTETESVTDDPDAIVIST
                     EETQEIIDDIFLAYEGYSVSSTYPESSKSYVINADKGKKLLVLRFDLYNGSNGAKKVNI
                     LEKNIKFQVILNGKNLGYTPVTFLPNDLSSYVGTIESRAHESLVVLTEIDQDMAKEIQS
                     LGMIVSINGAEQKVSLK"
ORIGIN
        1 tcgattatcg gaggtcaggt atgaacttga gagcatagaa tccaagcttc gtactataga
       61 taacaaagtt aattacagca ctatatatct tgatattaca gaggtttcca aatatacacc
      121 tgttgaggag aagagcgcag gaaagagaat ggtggaagga tttgtagaaa gctgcggatc
      181 cgttcttcac gctattgtag aattctttgt ctggtttgtt atatatattc ctcagcttgt
      241 gcttcttgct atagtaatta ctattgttgt attggtgatc aggagagtat taaagaaaaa
      301 gaagaaggtc gttgcagata aaacaaacga caatactcag aacgaatgat gaaaggataa
      361 aatgaaggat aattttaaaa caggttttat cactttgata ggccgcccca atgtaggcaa
      421 atcaacactt atgaaccata tgatagggca gaagattgcg attacttcca ataagcccca
      481 gaccaccaga aataagatca tgactgtcta tactgatgac gattgtcaga tgattttttt
      541 ggatacaccc ggtatacacg actccaagaa taagcttggt gaatatatga ccaaggtagc
      601 caagagtact cttgaagagg ttgacgtggt tttgtggctg gtagagccca gcactttcat
      661 tggagctggt gaaaagtcta ttatcgagga actcaaaaag tgcagaaaac ctgtgatcct
      721 tgtaatcaat aagatagata ctgtctccaa ggacaatctg gataaatttg aaaatgccta
      781 taggcaggaa atggattttg atagagttgt taaagtggct gcgctcaagg gtcagaacat
      841 agatgagctg atggacgcca tcaagaagct tcttcctttt ggaccgccat tttatgatga
      901 agaaacactt acagaccagc ctgaaagaca aattgcggcg gaaattataa gagaaaaggc
      961 ccttcgtctt ttacaggatg aggtccctca tggaattgca gtcaccatag agactatgag
     1021 aatgagggaa aaggttgtag agactccaag acccaagaaa aagagacacc agcatcctcc
     1081 aaaaaaaagt aagcttgaag ctatggaaaa agaactatcc agtgctttag ataatccaga
     1141 agatttagat gaggatttcg atggacctat ggtacttgat ctaagtgcaa ttcaggagcc
     1201 tgagcaggat tatgatcccg atggaatcat ggatatagat gcaactatta tctgcgagcg
     1261 agattctcat aagggtattg tcatcggtaa aggcggggct atgctcaaaa aaataggttc
     1321 ggcagctaga aaagatattg aggaacttgt tggatgccag gtaaacctac agatatgggt
     1381 gaaagtcaga aaagactggc gcgatgataa aactcagatg aagagttttg ggtacgatat
     1441 aagggacctt aaataacata tgtgtaatta acgctgatat attgcgaatg cctgatattt
     1501 cagctgatcg gaataaaaat ggaagatttc gtagtagttc gcggcattgt attaaaacat
     1561 gcacctgtgg gagattatga ctgggtcgct acaatcttta cggcagagag aggtaagata
     1621 acagcttttg ccagaagtgc cagaaagcct tcggccaagt tatccggact ggtagaaccc
     1681 ttttgctttg gcacatttaa actatttgca ggtaagaatt cgtatacaat agcggaagcg
     1741 gacatagaga actattttga aggctttagg gcggatttgg aaggtgcctg ttatggcacc
     1801 ttttttcttg aattatgcag tttttataca agagaaaaca atgaagataa agatctcttg
     1861 aatctgctgt atttttcact aaaggcgctt ttaaaagaga atataccgaa caggcttgtg
     1921 cgatgcatat ttgagctcag agctcttgtg atagaggggg aatatcccgg gattccggaa
     1981 gggcaaaagc tgcttgattc aaccagatat gcgatgggct ttataactac aagtccgctt
     2041 aataaacttt tttctttttc gctttcagaa gaagtacttg gagaacttga caggatcacc
     2101 aaggagtacc gtaatactta cattgacagg cctcttaaaa gccttgaaat gcttgaaatc
     2161 tttgagtatt gaaaaagaaa tactatttgg atataataac tttgtttgta tttttttagc
     2221 taaatagagg ggaaatagtg aaaatacata gttttaaaga gaataaaagc ttatatgcaa
     2281 gcgctatctc ttttgcaatt ctgacattta taggtgttac atcactaacc ggatgcggag
     2341 gggataatag gagagatact aaccttagta tcagtaaaga tggcaggata accaatacta
     2401 tttatgaagc ctttgacagg gattattacg atatagacga gttatccgac atggcaaatc
     2461 gggagatttc ttattataat tccgagtatg acaaaccaag gattgctata tcagatgttg
     2521 gagttataga ggatgatacg attggcaaaa ttgttatgac atttgaaacg tcatcggatt
     2581 attcacattt caatcagaca agcctatttt acggtactgt tcaggaagct attgataatg
     2641 gctttgagtt atccggatca ttggtagata aaaacggtaa tgtatttgat cttggatatg
     2701 aagattattt gaataaacat attgtcataa ccggtgagaa gacagtaata tatacaccat
     2761 acaatataga gtatatgaca agcggtgttg aacttttaga taaaaaggaa gcagatctta
     2821 ctaatgtaac aactgatttg gtacagatac ttctttcaaa ataaaaatat aagttataaa
     2881 cgtctgcagt ttgtggcagt cgcagaatgg aggattatgg aagcaaacgc aaaaacaatg
     2941 gacaaaatcg tagctctggc caaggcgaga ggatttgtat acccgggatc tgagatttat
     3001 ggaggccttg ccaatacatg ggactacggt aatctgggcg ttgaattcaa gaataatgtc
     3061 aagaaggctt ggtggcagaa atttgtacag gaaaatccat ataacgtagg tgttgactgt
     3121 gctattctta tgaatccaca gacatggatc gcttcaggac atcttggcgg cttctcagac
     3181 ccacttatgg actgcaagga gtgtcatgag agatttagag cagataagat cattgaagac
     3241 tttgctgcag agaataatat tacacttgag acatctgtag atggctggtc tcatgaggaa
     3301 atggagaact ttatcaaaga gcatagtgtt ccatgtccat catgcggcaa gcataatttc
     3361 acaggtatca gagaattcaa ccttatgttt aagactttcc agggtgttac tgaggatgcc
     3421 aaggatacag tttatcttcg tcctgagaca gcacagggaa tttttgtaaa cttcaagaat
     3481 gttcagcgta catcacgtaa gaaggttcca tttggtattt gccagatcgg taagagcttc
     3541 cgtaacgaga tcacacctgg taacttcact ttccgcacaa gagagtttga gcagatggag
     3601 cttgagttct tctgcaagcc gggaacacag acagagtggt ttgagtactg gagaaagact
     3661 tgctatgaat ggcttctttc acttggaatc aagaaagaaa accttagact tcgtgatcat
     3721 gatcctgagg agctttcatt ctactcagat catacaacag atatagaata tgcattccca
     3781 ttcacagatt ggggcgagct ttggggaatt gcatcaagaa ctgactatga ccttacaaga
     3841 catcaggaga catctggtca gcctatggac tactttgatg atgagactaa tgagaagtat
     3901 attccatatg ttgttgagcc ttcacttggt gcagatcgtg taacacttgc tttcctttgt
     3961 gaagcttatg atgaagagaa catcggaaca gaagagaaac ctgacatgag aacagtcctt
     4021 catttccatc cggctcttgc tcctgttaag attggtattt tacctctctc caagaagctc
     4081 aacgaaggtg cagagaagat ttatgctaaa ctctccaaga aatataactg cgaatttgat
     4141 gatcgtggaa atattggtaa gagatatcgt cgtcaggatg agattggtac tccattctgc
     4201 attacatatg actttgagtc tgagaatgac aacatggtta cagtaagatt cagagacagc
     4261 atggaacagg agagaattgc tatagacgag cttgaagctt tctttagtga caaattcgat
     4321 ttttgatcat tatcagacat agatcaaaga acctgagcta tttcaggttc tttgattatt
     4381 tcagtttata cggaggaatc tttgatgaaa caatttacag cacaggagct tcgcgaagct
     4441 tggaagcagt tttataagga tagaggacac gtggattgtg gcgctgtttc acttgtatca
     4501 gatggatcaa caggtgttat gttcaacgtt gcaggtatgc agcctcttat gccatatctt
     4561 cttggcaaga agcatcctat gggaacacgt ctttgcaatg ttcagggatg cgtacgtacc
     4621 aatgatattg attcagtagg cgataagagt catggtacat tctttgagat gatgggtagc
     4681 tggtcacttg gtgactactt taaaaaggag cgttgccagt ggagttttga gcttttgaca
     4741 cagctctttg gatttgatgc agatcacctt gctgccacgg tttttgcagg cgatgagaat
     4801 gcaccaagag atgaagaagg cgccaagtat cgtatagagt caggttttaa gcctgagaat
     4861 atctattatc ttcctgcaga agataactgg tggggacttg aatatggccc atgtggtcct
     4921 gacagtgaga tgttctatgt taaggatatg cctgattgtg gaccaaattg cggacctgga
     4981 tgtcactgcg gtaagtacac agaaattggt aatgatgtat ttatgcagta tgagaagcat
     5041 catgatggac atcttacacc tcttactcag aaaaacgttg atacaggatg gggacttgag
     5101 agaattcttg cattccttaa tggcgtagat gatgtatata agattgatct tcatgcacct
     5161 gtaatcgctt atattgaaaa agagagtggc cttaagtatg aatctgacga gaagacaaca
     5221 agatctatga gaattcttgc tgaccatact cgtacatccg ttatgcttat tggtgatgaa
     5281 gctaagcttc tcccttccaa tacaggagct ggttatattc tgagaagact tatcagaaga
     5341 gcagttagac atgcaagaac cctcggcctt aataaggacc agattcttgg agtagctact
     5401 atctatattg atgagtattc tgagagctat gagaatcttg ccaagaatcg caagtttgtt
     5461 cttacagagc ttgagagaga aattacaaga tttgagtcaa ctcttgaaaa tggaatgaag
     5521 gaatttagaa agattcttga taagacttct gcagcaggca agaaggaaat cgagggtaag
     5581 gatgctttct tcctttacga tacatttgga ttccctgtag aacttacagt tgagcttgct
     5641 gatgaagaag gttttactgt tgacgaagag ggctttaagg cttctatgga agagcagaaa
     5701 cagaaggcca gagagaacca gaatttctca gcaaaccttt caacaggtac aggacttttt
     5761 gataaccttg atgagtcagt ggcaaccgag tttcttggat atgagaaact tgaatgtgat
     5821 ggaactgtag cagttattgc tggagcagat gctcttgtaa ctgaacttac agaaggtcag
     5881 cagggcacta ttatcacaga taagactaca ttctatggca caatgggtgg tcaggttggc
     5941 gatatcggtg agattcttgg aagcaatggc gctaaatttg aggtaactga ggcggtcaag
     6001 gttgccggcg gcagaacagc acatgtcggt aaggttgtat caggaagctt caaggtatct
     6061 gataaagtga cacttagtgt agatgctgag aatagagcta agacttgtcg taaccattca
     6121 gcaactcacc ttcttcagaa agcccttcag atggttcttg gagacggtgt tgaacaggcc
     6181 ggatcatatc aggatcctga taaaacaaga tttgacttca gctatcatca ggctatgaca
     6241 gcagatgaga ttaagaaggt tgaggacata gttaacagca agattcttga ggcacttcct
     6301 gttgtgacta aggaaatgtc aatagaagat gccaagaaga ctggggctat ggctctgttt
     6361 ggtgagaagt atggtgagac tgtaagagtc gttaatatgg gagatttctc aattgagctc
     6421 tgcggtggta ctcatgtagc taacacaagc catatcggtc ttttcaagat attgtctgag
     6481 agcggcgttg ctgcgggcgt tcgtcgtata gaggctctta caggagacaa tgcaagagca
     6541 tattataaga atgttgaggc taatcttgga gaagcagcta agactcttaa aactacaccg
     6601 gctgatcttg ttgatcacat caagaagctt caggaagaac ttaaaaacct cagaagtgag
     6661 aatgagtctc ttaagagcaa agaagcacag gctgctcttg gcgatgtaat ggatcaggtt
     6721 cttgaaatca agggagttaa actcctggca acatcagtta agggtgttga tatgaacggc
     6781 cttagagatc ttggtgacca gatgaagact aagcttggtg aaggcgttgt tgttcttatt
     6841 tcagaagctg atggcaaggt aaaccttgta acaatggcaa ctgatggtgc tatggctaag
     6901 ggagcacatg caggaaacct tgttaaagca attgcaccta aggttggcgg cggcggtggc
     6961 ggtcgtccta atatggctca ggcaggcggt aagaatcctg ccggtattca ggacgcactt
     7021 gctgaagcaa agactgtcct tttgagtcaa ataaactaaa tattatataa aaatattaaa
     7081 aatatgcttg acagacatga taaatgtgct aaaattattc atgttatgtg agctaatggg
     7141 cttagtataa gcataataaa taacccaatc agtcatgtac ttgaagggac tgaagggagg
     7201 gtaagagtag agatgtcaac agtagtagta aaagaaaacg agactttgga tagcgcactg
     7261 cgtcgtttta agagaagttg cgcaaaggct ggtatccagc aggaaatccg taagagagag
     7321 cactacgaga agcctagcgt aagacgcaag aagaagtctg aagcagcaag aaagcgcaaa
     7381 tataactaaa acaaatttat gaaaagtcct tggagttttt ctctgaggac ttttttcttt
     7441 gcctttattt tgctggtgta tatgttcttt ttgttcctaa tatttcaagt ctgtgataaa
     7501 attatgattg ttacgtttta agcacgggat gaatttatgt ggatatatat actgattgca
     7561 attttaatac taataatact ttcagttatt gttatttatc atgatacgca taactttgtt
     7621 gtcaggagat atgatgttta ttctgacaag atagagggtg attatacttt tgctctttta
     7681 tcagatcttc atgggtatgt atatggcaat aataatgaca ggcttataga ggcagttacc
     7741 agagagaacc cggatgctgt tctgtgtgca ggggatatgt tcaccggaca caagataaag
     7801 ggggaaatac gatatcaggc aggttttcat gtgcttactg agcttgctgg tgaatttcct
     7861 gtatacatgg ctaatggtaa ccatgagcac aagataaaga catatacagt cgagtttggt
     7921 aatttgtatt ccagatatag gagcggcctt caaaaggccg gggtggtagt gcttgaaaat
     7981 gacagcgtcg atatacaggg cactaacatt cgaataacag gccttgaact taagcacgac
     8041 tattttcgca aggttatcaa acttgaaatg gaaaagggat atgtcgacaa aacggtaggc
     8101 catagcagta aaaataaatt tcaggttctt attgcacata atcctcagta ttttgatgaa
     8161 tatgcggatt ggggagctga tcttacagtc tccggccatg tgcatggagg gataataagg
     8221 cttccgctgt tgggaggcgt aatttcacct gcaatagctc ttttccctaa atatgatggc
     8281 ggtaagttta ccaaagacgg caagactatg atacttagca gaggacttgg gactcacagc
     8341 attcacgtta gaatgtttaa tcctggagag gttgatataa tcagggttca cagtgtaaac
     8401 aagtaatata tctgtttgtg ataatgtttt ttatagaggt aggatatgtc actagaagtt
     8461 aaacttcagg tgtttgaggg tccgctggat cttttgctgc acctgatcga taagaaccag
     8521 atagatattt atgatattcc gattgctact attacggatc agtatcttga atatataaat
     8581 gcgatgcaaa gtgatgatat ggatgttacc agtgagtttt tggtgatggc agctactttg
     8641 atcgatatta aatgtaaaat gcttcttccg aaagaggtta atgaagaggg agaagaggaa
     8701 gatcccagag cagaactggt tgaaaagctc cttgagtaca agatgtacaa gtatatggct
     8761 tatgaactta aggacaggca gatggatgca ggactttcct ggtttaggaa taagaatatt
     8821 ccgcaggaag tcaaggatta tgagatgccg gttgatttat cggaacttat cggcgatgca
     8881 actttgtcca agcttaacga gatttttcag gatctgctca agagacagga agataaggtt
     8941 gacccgatcc gtagtaaatt tggcaacata gaaaaagaag aagtagatat ggatgctaag
     9001 actctttata ttagagcttt cataagagaa cattcgcgtt ttagcttcag gcagcttctt
     9061 gaaaaacagc atagcaaaac agaaatcatt gtgacgtttc ttgttatgct cgaagaaatg
     9121 aaacttggag agatagaaat cgagcaggaa acgacgtttg gagatattat aattacgtcc
     9181 aggaaggcaa gttaatatga caagagaaga gggagcagct gtagtagagg ctattttatt
     9241 tactatgggg gattctgttg aaatcagtgc gctggctaag gcgatggaga tggatgccag
     9301 ggaaattaag aaatacattg attatttaaa agaaaaatat gaaagaagtg atagcggaat
     9361 tggaattata gagcttgaaa aggcagttca gctatgtacc aaaaaagaaa tgtatgaata
     9421 tttggtaaaa atagcaaaag ctccaaaaaa ggcagtttta acggattcac ttatggagac
     9481 tttgtctata atagcctata agcagccaat caccagactg gaagttgaga aaataagagg
     9541 agttaacagt gatcacgctg ttaacagact ggtagagttt ggacttgttc aggaattggg
     9601 aagactggat gcgccaggaa gacctctttt gtttggaacc acagaagaat tcctcagaag
     9661 ctttggcgta agatcacttg atgagcttcc atctatagga actgtgcagg ttgaggagtt
     9721 taaggctcag gctgaggaag agataaatgt taagcttgat atttaattaa cagatatatt
     9781 attatcaatt tgcagtcaat gatatttgca taaacaatta tttatataca attcataaat
     9841 tataggaaaa atgcgcaatt ttttatgcat ttttcctttt ttttgccatt ttttatgata
     9901 caatatattc tgacttatgt tgtgaaaata gcagtttttt gcatttttac aattcatttg
     9961 tgcatatatt attcaatata aaattttcgg aggtaaacaa atgagtagtt cttcacaagc
    10021 gagacaaaga atcaatgctt tgttggagga aaacagtttc gttgaaattg gtgctcttgt
    10081 gacagccaga aacacagatt tcaatctgaa acaggaagaa acaccatctg acggtgtagt
    10141 aaccggatat ggtgttattg acggtaatct ggtttatgtt tacagccagg atgcgtctgt
    10201 actgggcgga tctatcggtg aaatgcatgc cagaaagatc gttcgcctgt atgaactggc
    10261 aattaagact ggttcacctg taatcggact tatcgattca acaggacttc gtcttcagga
    10321 ggcaacagat gcccttaatg gctttggcga aatctatctt aagcaggtgg aggcttctgg
    10381 agttgttcct cagattacag ccatttttgg tgcctgtggt ggtggacttg cgataattcc
    10441 ttctatcaca gactttacat tcatggagtc tgagaaggct aagctctttg ttaattcacc
    10501 taacgctctt gatggcaact ataaagagaa gtgtgacaca tcagctgcta agtggcagtc
    10561 tacagagaca gctaatgttg acgttgtttc tgatgaagct tctatttatg cgcagatcag
    10621 agaacttgta tctattctcc cttccaataa tgaggatgga gattcatatc aggaatgctc
    10681 agatgatctt aacagagcat gtgagaatct tgatggtgct acagctgatc cttcacttat
    10741 tgctagacag atttctgaca atggcctgtt ctttgagaca aagagagaat acgccaagga
    10801 gatggtaaca ggatttatca gattaaatgg tgctaccgta ggtcttgtag gaaaccgtac
    10861 agctgtattt gatgagaacg gcaaggaagc tgagaagttt gctgacaagc ttacagcaca
    10921 tggtcttgag aaggctgcag aattcattac attctgtgat gcttttgatc ttcctgttct
    10981 tacacttaca aatgcaacag gatttggcac atctaaatgc gatgagaagc atgttgccaa
    11041 ggctgcaggc agacttgttt attcacttgc aaatgctact gttcctaagg ttaaccttat
    11101 tacaggtaag gcatttggca gtgcatacgt tatcatgaat tcaaaggcaa tcggtgctga
    11161 tgttactatc agctggcctg atgctcaggt tggtacaatg gatgctaatc ttgctgccaa
    11221 gatcatttgc gatggcaagg atgctgagac tgtatccaag gctgctgctg aatacgctgc
    11281 acttcagaac aatgttaaga gtgctgctgc aagaggatat gttgatgaaa tcgttgaacc
    11341 tgcagataca agaaagtatg ttgtaggtgc attcgagatg ctttttacaa aaagggatga
    11401 gcgtcctgcc aagaaacatg gcacagttta atgaagggag cactcaaaat gaaacataaa
    11461 acgttggttt tgggcgtaat gcttagttgc cttctgggac tgacagcctg cggtgcagag
    11521 gttaaatcca ataccgtaga aggaagcagg tattcgtctg atattttcac acaggaaagc
    11581 ttgaagggct ttgcagagtc acttgaagat aacaacttcg aaggttggta tttacaggga
    11641 ataactcctg acaacttcga aagcaactta tacttcgaca ttgcactgaa ttcaactgac
    11701 gagcgttatg aggttcttgc cagtggttat gacagctggt acaaggctct tgatgatctc
    11761 ggatataatt cagttgagac tcttgctaat gatatttttg ttaaagaggt taactacgaa
    11821 gttaacaagg atgatgaact tgtagtaaat gcagtactgc agggaaccaa gcatacagct
    11881 gatatggaaa tctacctcac aaacagagga gaagttacag atatcggtgt aacagttaat
    11941 aagactactg ctgagaagct tgagaatgca ggacttaata ctcttcttgg aatgggaatg
    12001 gcgtttacta tccttatcct tatttctctc attatttctc ttttcccaat gctctttggc
    12061 ggaaacaaga aaaagaagga gagcgataaa gaaatcactc agaaggcaat ggataataca
    12121 atcaatcaga ttgctgaaca ggaagacctt tccagcgatg ctgaacttgt agctgttatc
    12181 gcagctgcta ttgccgctta tgagggaagc gccggaacag atggattccg tgtaagatct
    12241 atcagaaaag taaataataa ctggaaaaaa cattaatgaa aggatcgagc acggatgaat
    12301 accctgctca tcgaaaggag atataaatga agaattatac tataaccgtt aacggaaacg
    12361 tatatgatgt tactgtagag gaaggtgctg gatcaggcgt tgctcctgta gccgcagctc
    12421 ctgctgttaa ggctcctgca gcacctgtta agaaggcaag cgctggcgca ggttcaatta
    12481 aggttgaggc tggtgcagct ggtaaggttc ttaagatcaa cgcaagcgtt ggacaggctg
    12541 ttaagaaggg cgacacagtt gttactatcg agtctatgaa gatggagatc cctatggttg
    12601 ctccttcaga cggaacagta gcaagcattg atgttgctgc aggtgattct gtagaagcag
    12661 gtacatgcct cgcaactctt aactaagtag acgtcagaga aatctaagtt tttcaataaa
    12721 cagaaatgag gataaaaaat ggattacatc gttaatacat tatctaatct ctggcaacag
    12781 actgcattta caacaatgac acctggtaac tatgtaatgg tagtagttgc acttgtcttt
    12841 atgtaccttg cgattgccaa gggatttgaa cctttacttt tggtaccaat ttcatttggt
    12901 atgcttcttg taaacattta tcctgaaatc atggctaaac cagtaggcga ttcagccggt
    12961 ggtcttctcc attatttcta tatcctggat gaatgggcaa ttcttccttc actgattttc
    13021 cttggtgttg gagctatgac tgactttggt cctcttattg ctaaccctat cagtttcctt
    13081 atgggtgccg gagctcagtt tggtattttc tcagcatact ttatggctat tgcttttgga
    13141 tttaatgatc agcaggctgc tgctgtatct attatcggtg gagcagatgg acctacatct
    13201 atcttccttg catccaaact gcatcagaca tcaattctgg gacctattgc ggtagctgct
    13261 tactcatata tggctcttgt gcctatgatc cagccaccta ttatgaagct tcttacaact
    13321 gacaaagaga gaaaaatcag aatgcagcag cttagagaag tatccaagct tgagaagatt
    13381 ctgttcccta tcattgttac aatcgttgta agtttgatcc tgcctactac agctcctctt
    13441 attggtatgc tcatgttggg taaccttttc agagagtccg gagtagtacg tcagcttcag
    13501 gagacagctt ctaatgcact tatgtatatc gtagttatcc ttcttggtac atccgttggt
    13561 gctacaacaa gtgctgaggc tttccttaat acaacaacaa tcatcattgt agttcttggt
    13621 cttattgctt ttgcctttgg tacagctgcg ggatgccttc ttggtaagct cctgtgcctt
    13681 gttacaggtg gcaagatcaa cccacttatc ggttcagcag gtgtttctgc cgtacctatg
    13741 gctgctcgtg tatcacagaa ggttggtgca gaatatgacc catcaaactt cctgctcatg
    13801 catgctatgg gacctaacgt tgccggagtt attggtacag ccgttgttgc cggtacattt
    13861 atggcggtat ttggtgtatg agtgataata tataaatatt tttgaaagga aaataaagaa
    13921 atggcagata tacagaaaaa accagttcgt atcaatgaga ctgtacttcg tgatgcacat
    13981 cagtcactta ttgcgacaag aatgcctaca gaagtaatgc ttcctatcat tgagacaatg
    14041 gatcaggttg gatacaacgc agttgagtgc tggggcggtg ctacattcga ttcatgtatg
    14101 agattcctta aggaagatcc atgggagaga cttcgtaagc tccgtgccgg attcaaaaat
    14161 actaaacttc agatgcttct ccgtggacag aacatccttg gatacaagca ttatccagat
    14221 gatgtagtag agtacttcgt tcagaagtct attgctaacg gtatcgatat catcagaatt
    14281 tttgactgtc ttaacgacct tagaaacctt gaggcttctg ttaaggcatg taagaaagag
    14341 ggcggacatg ctcagatcgc tcttgcttat acacttggtg atgcttacac agaagagtac
    14401 tggatgaaca ttgctaagga tatcgagagc atgggagcag attctatctg tatcaaggat
    14461 atggctggac ttcttcttcc ttatgaggca gagaagcttg ttaaggctct taagagcgct
    14521 acaagccttc ctattgatct tcatactcat tacacatcag gtgttgccag catgacatac
    14581 atgaaggcag ctgaggctgg tgtagatata attgactgtg ctatttcacc atttgctctt
    14641 ggtacttcac agccagctac agaagttatg gttgaagctt tcaagggaca gccttttgag
    14701 acaggtcttg atcagaaact tcttgctaag attgcagatc acttcagacc atacagagaa
    14761 gagtgtcttg ctagtggact tatggatcct aaggttcttg gtgttaacat taagactctt
    14821 atgtatcagg ttcctggtgg aatgctttct aacatggtta gtcagcttaa agagcagaat
    14881 gcaagcgata agtatgatac agttcttgag gaaatcccac aggttcgtaa ggacttcggt
    14941 gagccacctc ttgtaacacc ttcatcacag atcgttggta cacaggctgt tatgaacgta
    15001 cttatgggcg agagatataa ggttgctact gaccagacta aggaccttct tgctggtgag
    15061 tatggtaaga caattaagcc tttcaatcct gaagttcaga agaagatcat tggtgacaga
    15121 gaggtaatca catgcagacc tgctgacaga cttgagcctg gtcttgctaa gttcgagaag
    15181 gaagttgctc agtggaagca gcaggatgag gatgttctct catatgcatt gttcccacag
    15241 gttgctacag acttcttcaa gtatcgtatg gctcagcaga catcagtaga tgtatctgca
    15301 gctgatacca agaatggtgc atatcctgtt tgataaaagg taaatataat gcagcggcca
    15361 aaagcatatt tttgctttta gccgctgcat ttttgtggtg cgcctagcgg cgcacgtttc
    15421 taacgggtta aagtcccgaa tccgcccggt agtgggaagg atatagtcga aggcaagggt
    15481 gtccatcgcg agacggaatc tgaaggaagc tggatgtggg gaacatacta acccacgggc
    15541 aaatctccgg tctgacgtac agaaatctca tacgaggtta tgcatgaggg taaggctgcc
    15601 atacaagtcg aagcccaata actacacgga atcatgcatg ataaatgagg cagatggatg
    15661 gagaggaaga aacgtgtggt acctagggag gtctgcgtga aacgctctga aaggagtaac
    15721 caccgtacaa ggaaacgagg cggtgctgaa cacgcagaag tcagcagagg tcacagtagg
    15781 gatatggaca tggaaacatg gacatgctaa ccgaaggacc gaaatcagta ggagtcttaa
    15841 gtatgaccga gaaaggagga atgaccatta atggcagaaa acattgataa taatggctgt
    15901 tcgcaaagag atagtgcgga acacgaaggg tatgcgaaag cgcttaggtc attcaatcgg
    15961 atatggaaag aaagagacag tgcacagccg aagctcttgg aagcgatact gtataaggat
    16021 aactttaaca gagcgtacaa aagagttaag gcaaacaagg gagcgccagg tattgatggt
    16081 atgaccattg aagaggcact tccgtacctt aaggaacatc aacaggagtt aactgaccgt
    16141 atataccgcg gcaagtatac cccatcgcca gtcaggcgag ttgagattcc aaaaccagat
    16201 gggggtgtgc gcaagcttgg catacctacc gtgatagacc gaacactcca acaggcaata
    16261 actcaacagt tagtgcccat ctatgaacca ttgtttgcgg acggaagcta cggctatcgt
    16321 ccaaacagaa gcgcaaagga tgctatacag aaggtaaagg aatacgcaga acaaggttat
    16381 acatttgctg tcgttcttga tttgtccaag tattttgaca ccctgaatca cgaaatcctt
    16441 ataaatcttc ttcgaaagaa tgtaaaggac gaacgtgtag tgcagctcat aaagcgctat
    16501 ctgaagagtg gagtaatgga aaacggagtg gttattgaca cagaggaagg ttcaccgcaa
    16561 ggtggaaatc tatctccgct tcttgcgaat atctacctca atgagttcga ccaagagttt
    16621 ctgaaaagag gtgtgccctg tataagatat gcagatgaca tcgttcttct tgcgaaaagc
    16681 aaaagagcat cagagagact cttggaaagc agtactaaat atctcgaaga gaaactgaag
    16741 ctaacggtta atcgggagaa aagtcgtact gtcagtgcgt ttgctatccg aaattttaaa
    16801 ttccttggct ttgcattggg aaggaacgga agtggcatat atgtccgagt tcatccaaag
    16861 tcatggaaga agtttaagtc caagctgaaa gacttatctt cccgtaagtc tgtacagtcc
    16921 atcaagccaa gcctagagaa aatcaagaca tatacgagag gatggcttaa ctactatgga
    16981 atagccagca tgaagaacaa catagatgac attaataagt ggctctatca cagaatacgc
    17041 atgtgcatat ggaaacagtg gaaacttccc aagacaaaga agaggaatct tattaaactg
    17101 gggatacccg aatactatgc acatatcaca gccaacagcc gtagaggcca ttggtttgtg
    17161 tctggtatgg gtgcggttaa ctgtgcctta tcaaaagaaa gactgataaa cagtggcttt
    17221 tatgatttag ccacagccta tcagtctgtg cacgtcaact attgaaagcg ccgtataccg
    17281 aacggtacgt acggtgctgt gagaggacgg gtgctaatca ctccctccta ctcgatttca
    17341 ataagtcatg attattattt cacagaaatt ttatcaataa tgtgttaata tattaatatg
    17401 aatgagtata gaagacacag gcagagcaga aaacctatag agatcggcga gaggcagggc
    17461 agagagctta gaaagagcga tcttaacaga caaatgctag cgctggatga gatatcaggc
    17521 ttcagagtga ggcctggttt ttatggtatt aatggcgcta caatgcttac tgatggtgtt
    17581 aatttcaccg tttattctaa tggggctaca actgtaactc ttttgttata tcacagaggt
    17641 gaagataagc cttttgcaca aataccattt cctgaaagct ataaaattgg caaggtctat
    17701 tccatgattg tgtttggtct ggatatagaa aatctagaat attgttatag cgtagatggt
    17761 ccatgggatc cggaaaaagg tcttttattt aataaaaaca atgttctact tgatccgtat
    17821 gccaaagcag tatcaggaca gagaatatgg ggacagagac ttaataagaa tgggcagtac
    17881 agagcaagag ttgtcagaga taactttgaa tggaatgcta catcaaatct tggcataccg
    17941 atgtgtgatt ctgtaattta tgaaatgcac gttcgtggct ttacaatgga cccttcttcc
    18001 ggagttaaat gcagaggcac ttttgaagga ataaaggaaa aagttgaata cctgaaaaga
    18061 cttggtgtaa cagctgttga gcttatgcct atttttgagt ttgacgaaac cagggataaa
    18121 cgtgaagtta atggtaaggt cctccttgac tattggggat ataataccat cagttttttt
    18181 gcacccaaca ccagctatgc atctcaaagt gaatacaata aagaaggtgt tgagctcaaa
    18241 cacatgataa aagagcttaa ggataacgga attgaagtta tccttgatgt cgtgttcaat
    18301 catactgctg aaggcaacga aaatggacct tttatttctt ttaaaggatt tgataataat
    18361 atctattatc tgcttactcc tatggggcag tactataatt tcagcggatg cggaaatact
    18421 atgaactgta accacccgat ggtgcaggaa ctaatagtag agtgccttag atattgggtt
    18481 gaacagtaca gagttgatgg ctttaggttt gatctggcaa gcatactcgg aagagatcag
    18541 gatggatcac ccatggaaag accgccactt attcagcgcc ttgcctatga tcctatcctt
    18601 ggaaatgtca agcttatagc cgaggcatgg gatgccggag gaatgtatca ggttggtaat
    18661 ttccctgcat ggaaaagatg ggctgaatgg aatggcaagt atagagatga cattcgttct
    18721 tttttgaaag gggatatttg ggctgcacct gaagcagtaa agagaattac aggatcaatg
    18781 gatctttatg gcggggcata tcttggatat gaatcatccg taaactttat aacctgccat
    18841 gatggattca cattgtatga tctttatgcc tataacagta aacataatga agataatggt
    18901 tggaataata ctgatggagc caatgataac aggagctgga attgtggcgc tgaaggtatg
    18961 actactgatc agggcataaa cgatcttaga ttccggatga tgcgtaatgc tattacggtc
    19021 ttgatgtgca gcaggggaac tccaatgatt tatgccggag atgagtttgg aaatactcag
    19081 tatggcaata acaatgctta ttgtcaggat aatgagattt catggcttaa ttggcaacta
    19141 ttagataaga ataaagactt ttttgacttc tatagaagag ttatccagtt tagaagaaag
    19201 catccatgca tcagaaaaga ccttcctaat gccaaaagcg gctatccgaa tatatcgtta
    19261 catacagaaa atccggacaa tggtaatata acaggagaat ctaaggttgt ctgcgtcaga
    19321 tatgccggat tctataacaa aaaaggccat gatgacattg tatatatggc aataaatgcg
    19381 tattgggaag atgtacagat aatgcttcca aacccacctg agggtatgta ctgggcactt
    19441 tgcatagata ccggcgacga tgatggcaaa tactttttta acagaccaaa gcctcttacc
    19501 tggagaaaca aaactcttaa ggccagaagc gtaagtgtat tcattgcagc taatggagca
    19561 gaatatggcg gctgatgata aaagtaatgc tgacaatttt atagttgatg gatttcagtt
    19621 tatgtcggaa tcagatacgc aaaaagcatc ccttgattcg tctaagataa aacttctgca
    19681 atccagagtt aagtccagca aaccgacaga tattaaagcg gtttatgaga aagctataga
    19741 aaataagata tttaaaacac cgattggatg ggggtatctt acagggctta gaaggaaatt
    19801 attggaaagt ggatatgcag atgcagatct tattccgatt cctattgatg tctctttttc
    19861 caagcattca gctctcgata acctttcagt taaacagaga ataaagccac agaagcagga
    19921 aaaaaagctt gattttctca aaatattgtc aattatatgt aatatagtcc ttgttattct
    19981 tgttatacta ttgtttgtta tcgctgcaac tgcagaaagt gacaatataa ttaactacaa
    20041 gagtaatgtc acgaacagat atgcttcatg ggaacaggac cttaaagaga gggagaaaaa
    20101 agtaagagaa gcggaaaaaa ggcttggcat cactgatact tcaagttatt atgaggatac
    20161 agaaataata gacgacaatc aggaggattg acataatgga agatctaaaa atattagtag
    20221 ttgatgacga gagcagaatg cgtaagctcg ttaaagactt tttagtaaaa gacggatatc
    20281 tcgtagttga agctgaagat ggacagcagg ctctggatat tttttacgaa gataaggaca
    20341 tttctctgat catccttgac gttatgatgc caaagagaga tggctgggaa gtctgtaaag
    20401 aaatcagaac caactctaag gttccaatca tcatgcttac tgccaaggca gaagaaagag
    20461 atgagctgtt gggatttgaa cttggcgttg atgaatatat ttcaaagcct tttagtccca
    20521 agatacttgc tgccagagtt tctgctattt tgcgcagaac taatcaggct gccaataatc
    20581 agatcatgga aattggtgga atagtggtta ataaagttgc acatagcgtt cttgttgacg
    20641 gaaaagaaat tgatctgagc tataaagaat ttgaattatt atcattcttt tttgagaata
    20701 aaggagttgc tctttcaaga gaaaaaatcc ttaataatgt ttggaattat gattattttg
    20761 gcgatgccag aactattgat actcatgtca aaaaacttcg cggaaaactt ggaaaaaaag
    20821 gtgatatgat caagaccatt tggggaatgg gctacaagtt tgatgcagaa taatacgggg
    20881 aatcgggttg gctatcgcta tgggaaatga taaaaagttt aataagaccc attccatacg
    20941 ttttgaaatg agtatcgcgt ttatcgcgac aatgattgga acttttacgt tctgccttgt
    21001 tataaatctt ttgtttatgg agaactttta tgttcaaaac aaaagagaag caatcattga
    21061 ggcgtataga agcattgatc gggccacttc aacaggtgat ataacttctg aagaatttga
    21121 tcaggaaatc agacatatct gtgaacgata tgatattgag atgctggttc ttgacggtga
    21181 ttccaagaca gttaaatctt caaccagcaa tgctgaactt cttgcccaaa ttctttggga
    21241 aaacatgata agcccggctg gtggagaata cgaaattgag aatagggttg ttctcgatgt
    21301 aggagagaac tatactcttc aaagagatga agacaggtac ggaagaaagt atctggaaat
    21361 gtggggcgtt gtaggaaacg gaaaccttgt tctggtacgt tccgccatgg agagtattca
    21421 tgacagtgta gcaatttcca acactttcat gatctatgtt gctatagttg ctattgtggc
    21481 aggttctatt gtcattttat atatttccaa gaagatcact gatcctatca agagactata
    21541 tttcatatca gacgatatga agaaacttaa ttttgaagca aaatatgagt ctacagggga
    21601 ttaccacagt gaaatagatg cacttgggtc gaatatgaat gagctgtcag aaactcttga
    21661 gaagacaatc aaagaactca agaatgcgaa tatagcactc aaacatgata ttgccaaaaa
    21721 agaagaaatt gatgagatgc gtaaggaatt cctttcaaat gtatctcatg agctgaagac
    21781 tcctatagct cttattcaag gatatgcaga gggccttaag gaaggaatca gtgatgatga
    21841 agagagtagg aacttttact gtgaagtaat catggatgaa gctaataaga tgaatatcat
    21901 ggttaaaaag ctccttactc tcaatcagct tgagtttggc aatgaaagtg caaacatgga
    21961 cagatttgat atcgtcgaaa tgatcactaa ctatattaaa tctgcagatc ttttggcaag
    22021 acaaaaagat gtaactatca agtttgatga atatgagccg atatttgtat ggggtgacga
    22081 attcaagata gaagaagtac ttcagaatta ttacagtaac gctctaaatc atattgatgg
    22141 tgagaagata atagagatca aacttaccag aaaagacagc cacgtcagag tctctgtctt
    22201 taatacaggt aaacctattc cggatgatag tattggacac atttgggaga agttttataa
    22261 ggtagacaag gcaagaacca tagagtacgg cggtagtgga gtaggtttat ccatagttaa
    22321 ggctatcatg gaaggaatgc atcaggaata tggcgtcaag aactatgata atggagtaga
    22381 attctatttt gaattggaaa ccaagtaatc aatcctaaga gaggatggct tatgaggaca
    22441 aaaaagtatt ttggtatact gacggctata tgtttttctt tatgcttggc aggatgcgga
    22501 gaggcgtttc cggagcttac tgatgatgaa tataatcaga ctgtggagtt tgcagtaggt
    22561 cttttgatga aatattcaaa taatggacag gccaagctta cgtatgtcga tgctaaggaa
    22621 gtaactaagc aaagggaaaa agaagcagca ctggcagaga aagaaaagga caaagaaact
    22681 agtaagcctg ctccacagcc ggttcaggaa ccggtaaaag tgccagaacc aatccaaact
    22741 gaaatagaag aaccttcaat gtcaagtaca gaagatttat cattggatga tcaggggagc
    22801 acccagatta tagatagtgc tatcgatgct tcaagtgagg aagtggtaaa agagcctgat
    22861 gataccacaa ctgaaactga atctgttacc gatgatcctg atgctatagt gatttcaact
    22921 gaagaaactc aggaaataat cgatgatatt tttcttgcat atgagggata ctctgtatca
    22981 agcacatacc cagagagctc taagagttac gtaataaatg ctgataaagg caaaaagcta
    23041 ctggttctgc gatttgacct ttataatggc tctaatggag ctaaaaaggt taatatccta
    23101 gagaagaata tcaagtttca ggtaatactt aatggcaaga atctcggata tacaccggtg
    23161 acttttcttc caaatgattt atcttcgtat gtaggaacaa tagaatccag agcacatgag
    23221 agtcttgtag tacttactga gattgatcag gacatggcta aagagataca aagtcttgga
    23281 atgatagtaa gtattaatgg tgcggagcag aaggtttcac ttaaatagct ctgtttataa
    23341 aaagtttaga tgttgaaaag ccggcaaata ctaggtttgc cggctttatt ataaaaaaaa
    23401 tcaaaaaaag tgaaatttgt tgttgacact aatataaccg agtgatatat ttatattcgt
    23461 tgctgatgcg gacacgaagc accgcaaatt cagcagtgga gcggattgca agctcctgta
    23521 ccttgacaaa taaacagtaa tgcaaccctg aaaaattcca agagaattat tcagaacaag
    23581 aattagtaaa taacggacag aacaaaagcc aagcttagtt ctagcctgat caaactttta
    23641 aacgtgagag ttcgatcctg gctcaggatg aacgctggcg gcgtgcctaa cacatgcaag
    23701 tcgaacggag atataacgct gcagagattt cggtcaaagc ttgttgtatc ttagtggcgg
    23761 acgggtgagt aacgcgtggg caacctgcct catactgggg gataacagtt ggaaacggct
    23821 gttaataccg cataagcgca cagagtcgca tgactcagtg tgaaaaactc cggtggtatg
    23881 agatgggccc gcgtcagatt agccagttgg cggggtaacg gcccaccaaa gcaacgatct
    23941 gtagccggac tgagaggtcg gacggccaca ttgggactga gacacggccc aaactcctac
    24001 gggaggcagc agtgggggat attgcacaat ggaggaaact ctgatgcagc gacgccgcgt
    24061 gagtgaagaa gtatttcggt atgtaaagct ctatcagcag ggaagaaagg ctcgaaagag
    24121 agatgacggt acctgactaa gaagccccgg ctaactacgt gccagcagcc gcggtaatac
    24181 gtagggggca agcgttatcc ggatttactg ggtgtaaagg gagcgcagac ggtcaagcaa
    24241 gtctgaagtg aaaccccacg gctcaaccgt gggcttgctt tggaaactgt ttgactagag
    24301 tactggagag gtaagcggaa ttcctagtgt agcggtgaaa tgcgtagata ttaggaggaa
    24361 catcggtggc gaaggcggct tactggacag caactgacgt tgaggctcga aggcgtgggg
    24421 agcaaacagg attagatacc ctggtagtcc acgcggtaaa cgatgaatac taggtgttgg
    24481 gtgccatagg cattcagtgc cgtcgctaac gcagtaagta ttccacctgg ggagtacgtt
    24541 cgcaagaatg aaactcaaag gaattgacgg ggacccgcac aagcggtgga gcatgtggtt
    24601 taattcgaag caacgcgaag aaccttacca gatcttgaga tccagatgaa taagtggtaa
    24661 tgcatttagt ccttcgggac atctgagaca ggtggtgcat ggttgtcgtc agctcgtgtc
    24721 gtgagatgtt gggttaagtc ccgcaacgag cgcaaccctt gtccatagta gccagcagta
    24781 agatgggcac tctatggaga ctgccaggga taacctggag gaaggtgggg atgacgtcaa
    24841 atcatcatgc cccttatgat ctgggccaca cacgtgctac aatgtcgtaa caaaggggag
    24901 cgaaggagcg atccggagca aatctcaaaa ataacgaccc agttcggact gtaggctgca
    24961 actcgcctgc acgaagctgg aatcgctagt aatcgcagat cagcatgctg cggtgaatac
    25021 gttcccgggt cttgtacaca ccgcccgtca caccatggga gtcggaaatg cccgaagccg
    25081 gtgacttaac cgtaaggaga gagccgtcga aggcaggtcg gataactggg gtgaagtcgt
    25141 aacaaggtag ccgtaggaga acctgcggct ggatcacctc ctttctaagg aaaagagaag
    25201 gaatgaagta gggagttgta ttactgttta gatgccaagt gcatcaagat atttctggtg
    25261 gtgatgcgtt taggggtaac acccgttccc atcccgaaca cgacggttaa gacctaaacg
    25321 gccgaaagta cta
//
