LOCUS       NZ_CP102267.1          23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP102267.1 Blautia wexlerae DSM 19850 chromosome, complete
            genome.
ACCESSION   NZ_CP102267
VERSION     NZ_CP102267.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:42:28
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 438721
            Orig. end    :: 461970
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[448721:451970]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1413..2870
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_375"
                     /sec_met_domain="FGGY_C (E-value: 2.9e-36, bitscore: 123.0,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 1.8e-78, bitscore: 261.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARNLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(2982..3917)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_376"
                     /sec_met_domain="LysR_substrate (E-value: 2.1e-31,
                     bitscore: 106.9, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.6e-16, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFEHYIYQKEQ
                     LLLAVPKNYSVNTRLQEYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4033..5457
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_377"
                     /sec_met_domain="Lyase_1 (E-value: 1e-92, bitscore: 308.9,
                     seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 3.7e-20, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5566..7251)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_378"
                     /sec_met_domain="FTHFS (E-value: 2.5e-273, bitscore: 905.3,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGRTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_379"
                     /sec_met_domain="OKR_DC_1_C (E-value: 1.1e-11, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 2.3e-124,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_380"
                     /sec_met_domain="Spermine_synth (E-value: 1.3e-51,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 2e-13, bitscore:
                     48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_381"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.6e-41, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 7.7e-34,
                     bitscore: 114.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKVDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_382"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 8.3e-13,
                     bitscore: 46.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTGASLGLRINPECSTQRDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_383"
                     /sec_met_domain="PAD_porph (E-value: 2.4e-126, bitscore:
                     419.3, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGDFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTQED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14489..15367
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_384"
                     /sec_met_domain="CN_hydrolase (E-value: 4.6e-54, bitscore:
                     181.4, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15670..16131
                     /locus_tag="ctg1_385"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGRRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIVLLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             16335..21044
                     /locus_tag="ctg1_386"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVEYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEILVSQTKQDVKAVNVVITDELPSCLQLLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASAESNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQRQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGEAETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEMVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEAYVKAKAEPTATPTPSVTPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYANSGGYSGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             21041..21928
                     /locus_tag="ctg1_387"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     IAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYERPEFLKKCPEIEITTPKRKFLYKIFSVEQASSKS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             22120..23211
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_388"
                     /sec_met_domain="Peripla_BP_3 (E-value: 2.3e-31, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
ORIGIN
        1 atccatatgg ttcaggctct tgaagatatc aagaaagcgg gatgtaatgc actttgtgta
       61 tatcttggaa acttcggacc ggaaatttcc gaaacacttc ttgcaaagca tttcgaagga
      121 ccgaagatgt tctgtgcagc agcagaagaa acacaggata atctgatcca gggacgtgga
      181 gatgcatact gcggtatgtt aaatgcaagc tataacttac agcttcgcaa tgtaaaagca
      241 tatattccgg aatacccggt tggtgacgca gaagactgcg cagatatgat ccatgatttc
      301 cttccgatcg caagagcagt agaaggactc agcaacttaa agatcatcag cttcggacct
      361 cgtcccacaa acttccttgc ttgtaatgca ccgatcaaac agctttacaa ccttggagtt
      421 gagattgaag agaattccga acttgacctg tttgaagcat tcaacaaaca tgccggagat
      481 gagagaatcc ctgcaattgt taaagaaatg gaagaagaac tgggtgcagg aaacaagaaa
      541 cctgagattc ttgcaaaact tgctcagtat gaactgactc tgaaggactg ggtagaggct
      601 cacagaggat atcgtaaata tgtaacctta acaggaaaat gctggcctgc attccagaca
      661 cagtttggat ttgttccttg ctacgtaaac agccgtctga ctgctcaggg cattccggta
      721 tcttgcgaag ttgatattta tggtacatta agtgagttca ttggaactgt tgtaagccag
      781 gatacagtta cactgcttga catcaacaac tctgtaccga aggatatgta caaagagtct
      841 attgagggca aatttgatta cacactgaaa gatacattta tgggattcca ctgcggaaat
      901 acagcttcca gcaagctttc tttctgtgag atgaagtatc agatgatcat ggcaagatct
      961 cttccggtag aagttacaaa cggaactctt gaaggagata ttgttcctgg agatatcact
     1021 ttctatcgtc tgcagagcac tgctgataac aaactccgcg gatatattgc acacggtgaa
     1081 gttcttccgg ttgcaacaaa atctttcggt gcgatcggcg tatttgcaat tcctgaaatg
     1141 ggacgtttct accgtcatgt actgattgag ggaggatatc cacatcacgg agcagttgca
     1201 ttcggacatt atggaaaagc tttgtttgaa gtattcaaat acatcggtgt tccggttgaa
     1261 gagatcggat acaaccagcc ggcaggtgta agatacccga cagaaaatcc atggggttaa
     1321 ttcagataaa cagactgaca ctataaattt taatacatcc cgggggttta ccctgggatg
     1381 tattagatta gaaatagaaa aggagagcac ttatgtatta tatcggtatt gatcttggta
     1441 cttccgctgt aaaacttctt cttatggaag aatcaggaaa aatctgtaac atcgtatcca
     1501 gagaatatcc tttattcttc ccacatccgg gctggtctga gcagaaaccg gaagactggt
     1561 ttgcgcagag tatggaaggc atgaaagagc tgacaaagga tatcgacaga gcgcaggtag
     1621 caggaattgg ttttggcggc cagatgcatg gtctggtaac acttgacaag gatgataatg
     1681 tgatccgtcc tgcaatcctc tggaatgacg gacgtacagg cgaagagaca gaatatctga
     1741 atacagtgat cggaaaagac aaactttcac agtatacagc aaatattgct ttcgcaggct
     1801 tcacagcacc gaagatcctc tggatgcaga aaaatgagcc tgagaacttt aagaaggtag
     1861 taaagattat gcttcctaag gattatctgg catatcgtct gtccggttct ttttgtacag
     1921 atgtttctga tgcttccggt atgcttcttc ttgatgtgaa gaaccgctgc tggtcaaaag
     1981 aaatgttgga gatctgtgga atcacagaag agcagcttcc gaaactgtat gagagttggg
     2041 aagtagtagg aactctgaaa cctgagattg cgaaagaact tggattcagt gagaatgtaa
     2101 aagttgttgc aggtgcaggt gacaatgcgg cagctgctgt aggaacaggt acagttggtg
     2161 acggtcagtg taatatttct cttggaacat ccggaactgt gtttatttcc agtaaaaact
     2221 ttggtgtgga cgaaaataac gcacttcatt ctttctgtca tgcagatgga agctatcatc
     2281 tgatgggatg catgctcagc gcagcttcct gtaacaaatg gtgggcagag gagattcttc
     2341 agacaaagga tttcgcagca gagcaggctc caattcagaa gctgggagag aatcatgtat
     2401 tcttccttcc atatttgatg ggagaacgtt cacctcataa taatcctgat gcaagaggtg
     2461 tattcttcgg aatgtccatg gacagcacaa gagcagacat gacacaggct gttctggaag
     2521 gtgttgcctt tggtcttcgt gattccctgg aagttgcaag aaaccttgga atcaagattg
     2581 agagaaccaa gatctgcggt ggtggagcta agagcccact gtggaagaag atcattgcaa
     2641 acgttatgaa cctgaaggtt gatgttctgg agaacgaaga aggaccgtcc atgggtggag
     2701 ctatgctggc agcagtaggc tgtggtgctt acccggatgt agaaaccatc ggtaagaaat
     2761 ttgccaaagt tgttgatacg gtagaaccgg atcctgaact ggttgcaaaa tatgaagaga
     2821 gatatcagaa gttcagaact ctgtatccgg cgatgaagcc attgttctaa tcgaatatct
     2881 gcctgacata ctggggttgt tgtgcttatt tagcacaaca accccatttt gacgtacatc
     2941 tgatgatgac caatcaccat agcctatttg attatgacat atcaggaaaa gggcagcttc
     3001 aggaattctt ccatggctct gctgatatag cggcctttct tccagtaaaa aaacacagtg
     3061 cgtttactgc tctgaccggg cagcttataa aaaacaagtt ctgaatttgt tggaactctg
     3121 gagagcagaa gatccccgat gaaagtgata cccattccca aacatgcaat attataggca
     3181 gtcatctgct gatccaggcg aaatactaca gaaggcgaaa agtgattttc ctgacaaatg
     3241 gtaagtgcac gcttaccggt atcattatct gaacgaagaa taataaatgg ttcgttctcg
     3301 aatttgttta atggaacaga aggaatatga gaagaacgga actgcccgtt ccggatttcc
     3361 tcaataggaa tctgatattc ctgcagtctg gtatttactg aataattttt gggaaccgct
     3421 agaagaagtt gttctttctg gtagatataa tgttcaaaaa tctggttatc cagaatacag
     3481 ttatcaatta ccagatctaa ctttccggcc tggagaaact gggatagctt tgctgtactt
     3541 tcttctacaa gagaaatttg aacatggggg aatttttggg aaaaatcagc aataagggga
     3601 ggcagaatcc acgaagaaaa aaagttactg ccacctacat taagagttcc tgttttgaga
     3661 tttcccagat ccagtaggta gttttcgaga ttattttcaa tatccatgac tttttcaaca
     3721 gcctgtatat aatgttttcc aacttcagtt aactgcaaag gtttggtact tcgatcaaaa
     3781 ataggatagc caatacggtt ttccacacgt tttacattgg cgcttaaaga aggctgcgaa
     3841 atgaaaagag cagcagcagc tttggaaaag cttttttcct tgtagacctc atagatgtat
     3901 tccattccct gaaacatata aactcctcca atatataatt taaacactat atattttata
     3961 aaaatatatg tatttgatta tattatagca gagatatata atgagggcaa atacatggga
     4021 gggcgaataa ctatgaaaaa aacagactat cgtgtagaaa gggattctat tggtgtaaag
     4081 gatattccgg aagatgtata ttatggagta caatccttac gtgcggctga aaatttccac
     4141 attacggggc tgaatatgca tccggaaatt attaacagtc ttgcatacat aaaaaaagca
     4201 gcagcgataa ccaattgtga ggtggggctt cttgagaaga aaaaagcaca ggcgattgtc
     4261 caggcatgtg atgaaattgt ttcaggaaaa ttccataatg aatttattgt ggatcctgtt
     4321 cagggaggag ctggcacatc tttaaatatg aatgccaatg aagtaattgc aaatcgcgcg
     4381 attgagatac tgggaggaaa aaagggcgat tatacaatta taaatcctaa cgatgatgtg
     4441 aattgtggac agtctaccaa tgacgttatt cctactgccg gtaaaatgac ttctcttcgt
     4501 ttgttgcaga atctgaaaaa acagcttctt cgcctctatg atgctcttaa tgaaaaagct
     4561 acagagtttg atcacataat aaaaatgggg cgtacacaga tgcaggatgc agtaccaatt
     4621 cgtctgggac aggaatttaa ggcatattcg gtagcaatca tgcgtgatat ccacagaatg
     4681 gataaagcaa tggatgaaat gcggactctt aatatgggag gtactgctat tggaacagga
     4741 attaatgcag atgagggcta tctgagaaga attgttccaa atctcactga aatatcggga
     4801 atggacttta tacaggcttt tgatctgatt gattccactc agaatctgga tccatttgta
     4861 gccgtttccg gtgctgtgaa agcatgtgcg gtaactcttt ccaaaatgtc aaatgatctc
     4921 cgtctgatgt cctccggtcc acgtactggt tttggggaga ttaatcttcc ggcaaaacag
     4981 aatggttcct ctattatgcc aggtaaagtt aatccggtta ttcctgaagt agtgaatcag
     5041 gttgctttta atattattgg taatgatgtt accattacca tggctgcaga ggctggtcag
     5101 ctggaattaa atgcgtttga gccgattatt ttctattgca tgttccagtc tatcgatact
     5161 cttggctatg cagtccagac attggtggat aattgtattg taggaattac ggcaaatgaa
     5221 gaaagatgcc gttatctggt agaaaacagt gtaggtatta tcactgcaat cagcccccat
     5281 cttggatatc agaaggctgc ggatattgca aaaaaggcaa ttaagacagg tgaatctgta
     5341 agaagtctga ttctgaaaga aaagcttatg gacgaggatg aacttaatcg cattctggat
     5401 ccgatccata tgacggaacc tggtatttcc ggaaaagatt atcttataaa aaaataaaga
     5461 aaaaaacagg cgggaaaatc ttcccgcctg taaaatcgtc tggacacata tcatatataa
     5521 atatgatttt tatatttttg aattattcga ttgatttcaa ctggattaga acagacctgt
     5581 gatcttacct gtctcgtcta catcgattct ctcagcagcc ggaactttag gaagacctgg
     5641 cattgtcatg atctcgcctg taagagctac gatgaatcct gcaccagcgg aaatcttcag
     5701 gttacgtact gtaacttcga agtcagtagg agcacccagt ttggtctggt catctgttaa
     5761 gctgtactga gtcttagcta cacagatcgg gcagttgccg aatccaagag cttctaactg
     5821 tttcgcctgt ttctgagcgt tagctgtcag aactactttc ttaccgccat atactttctg
     5881 aacgatctgg ttcagtttgt cttcgataga accttccagt tcatatgcat aggagaagtc
     5941 gtttggttct tcaacaagac ggataacttc ttctgcaagt ttgattccgc cttcgccgcc
     6001 ttttgcccat acttcagaaa gagcaacgtt aacgcccagt tctttacatt tagcttctac
     6061 aaagtcaagc tctgcttttg tatctgtagg gaatgcgttg atagcaacaa cacatggaag
     6121 tttgtatacg tttttgatgt tggaaacgtg ttttaacagg ttcgggatac ctttttcaag
     6181 agcttccagg ttttcattgt taaggtcagc tttagcaacg ccgccgttgt atttcagggc
     6241 acgtactgta gctacgatta caactgcgct tggttttaaa ccagccatac ggcatttgat
     6301 atcaaggaat ttctcagcac caaggtcagc accgaaacca gcttctgtga ttgcataatc
     6361 agcaagcttc atagccatct ttgtagctgt tacagagtta catccatgag cgatgtttgc
     6421 gaatggtccg ccatgtacga ttgcaggaac gtgttccaga gtctgtacaa ggtttggttt
     6481 cagagcatct tttaacaggg ctgtcatagc gccttctgcg tgaaggtcac ctgctgttac
     6541 aggtttctgc tcggaaactt ttccgtatgt atatccgatg atgatcttgg ataatctttc
     6601 tttcaggtct ttgatgtcgc ttgcaagaca gagaactgcc atgatttcag atgcaactgt
     6661 gatgtcgtat ccgtcttcac gaggcatacc gtttgttctt ccgccaaggc cgtctactac
     6721 gttacgaagc tgacggtcgt tcatatccac acatcttctc catgtgatct tacgtgggtc
     6781 aatgtttaat gcgttgccct ggaagatatg gttatcgatc atagctgcca gtaagttgtt
     6841 agctgcgccg attgcatgga agtcacctgt gaagtgaagg ttgatgtctt ccataggaac
     6901 aacctgtgca tatccgccgc ctgctgcacc gcctttaaca ccgaataccg gtcctaagga
     6961 tggctcacga agagctacca taacactctt gccaagtctc tgcataccat ctgcaagacc
     7021 tacagtagta gtagttttac cttctcctgc aggagttggg ttgatagctg taacgaggat
     7081 taattttccg tccttcttat cgctttcttt cagaagattg tagtcgattt ttgctttgta
     7141 ttttccgtac tgctccagat atttgtcgtc aatacctgct ttttctgcaa tctgagtaat
     7201 tggaagcatc tcgcattcct gtgcaatttc aatgtctgat ttgaatccca taattgtttt
     7261 tctcctttcg tttccgcata acatgaaaaa cttctgttgc tgttcactcc gcgatcagca
     7321 acaattatta attgaaagaa gtattggccg atctgcctgg tattcctgat ttctgccctg
     7381 aaagttataa aaaaaggcca gtatctgaat atttcaaata ctgcccagac ggtcggctcc
     7441 cacaaacctc cgactccacg tggtttgcac tccactcttt ccgtcagtac tcgaaggttc
     7501 tttcaattga tgaatacaat atatcatttt gagaaaaaaa tgtcaagaaa atttttgttg
     7561 aaacgtcaaa aaatgtgagt aaactggata aaagttgtgc aaattgataa gagaagagaa
     7621 tcgtaatccc tggtaatgaa agaaaatacg ttttctcaag ggaagaaatt gttaaaaaat
     7681 agacacagtt ttccctgata aatgaagaaa atataaaaag cgggtaaagc tagagcgtgt
     7741 ctgaaaaatc attcccgcaa tctgcacgcc cccactttgc gggatatttc acccgaattc
     7801 agttgccgta gcccgctacg gcgccctcat ccgggcaaaa tatcccacaa attgtgacgc
     7861 acatcttgca gaaagccttt ttcagacacg ctctagtgca aaatatggaa aatggaattg
     7921 acaacagttc agaagatatg ttattctcat ctttagtatg aaaagacact atcgttttca
     7981 tgcaaatatt tgctcacatt cagagacagt ttctgaatgt taagccatac ggacaggcgg
     8041 ggcagttgcc gggtgggaga caccacatta ttgattgagt tagaagctca aattttataa
     8101 gttgattact ttataataat cagtgcgtaa gcacacatca tcttgtgaaa cggtcaataa
     8161 gagcatagca tatatttgcc agcgattgaa gacgacagca gtcatgaata tttcagaata
     8221 cgggaacagg cacaggatac agacggattt atacgggaaa tccggtcagt atataaagag
     8281 acagagcctg agaaattcta tagatcatga gagaagcaga tggtgaatga acttatctgc
     8341 ttcttttttt gtgcagatat agcaaatata aaggatatgg ttggagataa acgttttgcg
     8401 aggatgtgtc tcacatgcgt tcgacttgaa tatatagaga aataattgaa tcattgtgcc
     8461 ggtttgaggc agtatacaat tgctgaatga tagaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccggagctt gcacagttgc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc acccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcgc atgcattcct tatggtagga ggaaccacat
     8821 ctgcagtgca gagcatgatc ctgtctgtct gcaaggcagg ggataagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg cggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgcg cagctgggca tttcccttgg catggaagtc agtcaggtgg
     9001 agaaggctat ggatgagaat ccggatgcgg tggcagttct tgtaaataac cctacctatt
     9061 atggaatttg ttcggatctg cggactatcg taaagaaggc tcatgcaaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtatccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agcgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcactcaga ggagaggaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gttattatgc atatggtatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc catttataca ctgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccattgg agacaggctt caggatattg
     9661 agaggctggt aggggcattg gctgatattg aacgtctgta taagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctggaga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaaca tcttcaggtc ctgaaagggg gtatctgatc atggaattat ggtattctga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttgggagat ttgtggctct
    10141 ggacggtgag atcgtattct ctgataaaga tgaatttatt tatgatgaga tggttacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg atcatcggcg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtggaatc
    10321 cgataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacgg agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggtttttcgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggtggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaatagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaaggtagat
    11041 gcggataatg cagcagaggt cgcagaattg atcagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctacgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgagaaatt taaggaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgct tatgccctga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaacggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct acgatttccc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa aaatattccg
    11641 ggagtacaga ggatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaatgg acaggagatc
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttccg gctttgcgct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatagag gaactggatc gtatctgtga
    12421 ccatattatc tttaattcca cagcacagct gaagaaattt aaagaagtgt gtaccggagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag agggatcatg cgatctatga
    12541 tccctgtgcg ccgggttcaa ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatc gacggactgc attttcatac gctctgcgaa cagaatgcgg atgacctgga
    12661 gaaaacattg caggcggtag aggagaagtt tggagaattt ctgtctgagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatgagat
    12901 cagaacgctg attttggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgcctgg caggagatgt gatcggagat tattcctttg acagagagat
    13081 ccggatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcacaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agcttgggaa tgtttccggt gtgactttgc tggaatgtga gacagatgac gcctgggcca
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggagga gactttgatg gactttaccg gaactgggag aaggacgaca
    13681 gggtggctgc ctttatctgc aggactcttg gttgtccatg tctggatgcc agaccttttg
    13741 tgcttgaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtcttt ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaag ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccag gaagatgtgg atggctttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggctgcca gttacgtgaa tttctatatt tccaatggag
    14221 ggatcatcct tccacaattt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gttggcggtg
    14341 gaaatattca ctgtatcacc cagcagattc ccggaaaaaa tatctgacct tgatgcagaa
    14401 aactttgaga gtcatgtgtt tgagggttat tacctgaaag ttatgaaaaa acttacttat
    14461 gtaaacagga gcaggaggaa cagacaggat gagaaatgta acagtggcag cagttcagat
    14521 gaaatgcagt aaaagtgtgg agaaaaatat tgcccatgca gaggaactgg tgcgtcaggc
    14581 agcagcaaag ggagctgaga ttgttcttct gccggagctt tttgaacggc cctatttctg
    14641 ccaggagcgc agatatgagt attatgaata tgcgcagact gcagaggaaa accctgcagt
    14701 gcgtcatttc agcagggtag cggcagagtt ggggattgtg attccggtca gcttttatga
    14761 aaaagaggtc aataatactt ataacagcgt tgcggttctg gatgcagatg gaaagaatct
    14821 cggcatttat cggaaaacac atattccgga tgaccattat tatcaggaaa aattctattt
    14881 cacaccggga gatactggct ttaaggtttt tgataccaga tttggaacca ttggagttgg
    14941 aatctgctgg gatcagtggt tcccggaaac ggcaagatgt atggcactgc agggcgcaga
    15001 gcttctcttt tatcccactg ccatcggaag tgaacccatc ctggaatgtg acagcatgga
    15061 acactggaga agatgtatgc agggacacgc tgcctccaac ctgatccctg tgatcgctgc
    15121 caacagaatc ggtgaggaaa cagtagagcc atgtccggaa aacggaatgc agaaatctgc
    15181 tcttaatttt tacggctctt cttttatcac agacaacaca ggtgctctct gtgcagaact
    15241 gcccggaggg gaagaggggg tgcttgtaag cacttttgac ctggatgcat taaaggcaga
    15301 cagactgaac tggggacttt tcagagaccg cagaccggag atgtatgcaa aaattgtcgg
    15361 gaaatgatgt ataagtttag ttattgttca cacaccacta tcccgcgagg tgttttggca
    15421 tgaatatgcc aaaatcccga gacatacaag ccaaaattcc attgccgcag gcaatctgga
    15481 atgaattttg gctcagttac tgagaacgga gtgaacagta attgagttta taagaatttc
    15541 ataaaaagtt tatgattata ttagttgcta cctgcggtat atatggtaaa ataagagtac
    15601 gaacgttact gataacggag cgagcagtag agttttgaca tgtatttctg gcaaaatgga
    15661 gtgtagaaga tgaacagaaa agaatttttg gaaatcctga gaagccagct tgccggtcag
    15721 atgcaggagg gcaaagcagc agcacatatc aggtattatg aagattatat acagtctcag
    15781 gtacgtggca gacgttcaga gcaggaagta ctgcaggaac tgggagaccc gcatctgata
    15841 gcaaaaactc tgatcgatac agatgatgga agtacacagg aagattacgg agagtattct
    15901 tcttacggaa gcagttatgg caatgagaca gagcttcctc atcagcagga gaaaagatgg
    15961 aaaaaagtaa tcgatctttc tacctggcat ggcagggctg ttgttattgc agcggcggct
    16021 gttataattg ttttactgat actgataatc ggagttgcga ttccgttttt tattattctt
    16081 gcaattattc tttattttct ttcatggctg aagaaaagaa atgatcaatg aaaatctgtg
    16141 cagggtttca gaaaagaaac cctgcgcaga atcttaaaaa tcttaagtgt aaacgttctt
    16201 gtttcacgat attaattccc cttgaatatt tataatcata caatctcaac ttatttctat
    16261 tctttaatcc tgccaggtgc agggaaaaat cccacattca tttttatatt ttttgttcgg
    16321 aaaggagacg gaaaatgaaa cacaatttca aactgaaaga acgccttgga gctttgctgc
    16381 ttgcaatgct ttttattctg caggcaattc tggggcttgt gcctgtctgc gtaactcagg
    16441 cggcaccgtt aactgtagaa acatgggaca gtgacaaggt ggtagagtat ggttatcgct
    16501 ttaacatgaa gtttcagccc ggaattacca catatgaatc ttttgggtgt gataatctgg
    16561 acagggaagc tttttcagac aatggaaaaa gcgaacgtga cacagagtgc gttcgtgtag
    16621 gagcggacta taaagccgga agcgcaggga tgcgttataa caatgtagga aaagatggaa
    16681 atggaaatat tgttgatgtc agactcattc ttgtgggagt agagaatgca gaaccccgtt
    16741 atgatctgcg cactgcagaa tcgattgttc agaataaagg cggagctacg tttgcatgga
    16801 aagataatga agcttatcca atggttggct tttccaaaaa cagtatcggt gtatttattt
    16861 attctgtagg atacgcaaag gttaagtttc agtttctgaa gcatggaaca gaagaaacac
    16921 tgccgatcag tggccatgga accatacgtg atattgatgc gggacaggga gtccgtattc
    16981 cgtcagacag cagtctggat aatgcatatg ttctgaaaaa caatgattat ctgacggtag
    17041 atggaaattc tgtaagctca ccccttggtt ccgttgagcc ggatgatccg agaggatggc
    17101 tgaatctttt ttataataca gataatttta cggtagaatt ctgtcatcag ttcagactgg
    17161 ataaatggga taaaagtcgt gaagatgcca ttgcaaaagc cggttctcag gaaagatggg
    17221 cagagattac aagaaataaa tatctggatc catcaggcaa cagttattgt ccgaacttta
    17281 aaggacagaa atactgtaaa gcatatgcat attttgattt tacatcctat tgtttcggcg
    17341 atgttgagat gaaaaaagca cctgagaaac gtgtgggaga ggcaaactgt acatgggaac
    17401 aggcagctgc tgcatcaaaa gaaaaacctt ttggcattcg tcagggacag gaatttcagt
    17461 atatgatccg ggcagaggtg acacccaata gactgaaatc ctttgtggta caggatatac
    17521 ttgaggattg tcttactata gaggatgcat caaaagtcag tattgtgaat gatgcagggc
    17581 agacagtgac agactggttt gatgttgctg ttgaaggaca gaaagtgacc tgcagggcca
    17641 aagcagagag ccttcaggat gaagcattta cagataatca gacttacaca tttactttaa
    17701 aagtacgcca gagaccggaa tcagaaatta atatttcaaa ataccttgca gaggatggat
    17761 acagtattct tgtaccaaac catgcatcca tgagttatga acgtacaaac ggaagcggag
    17821 atacaatgga tacggaaaca gtgtgggtaa agggtgtgat tccaccggaa ctggaagtaa
    17881 agaaaaatac ttctcagtat gaatggaaaa cgggagatat catagattat gagattctgg
    17941 tttctcagac aaaacaggat gtaaaagcag taaatgttgt tattacagac gagcttccat
    18001 catgtctgca gcttctggaa gggcagtatg ctgtagagac aagtcaggga ggtgagaact
    18061 gtacgcttac cggacaggga gaaaatggat ggaaagcaga gtgtccgtcc ctgaagtatg
    18121 gggagacgat cacaatccgt tttaaatgtc aggcatctgc ggagtccaat ggacaggaat
    18181 gggaaaatat tgtgactgca acagcggata atctgatcaa tcctgagaca ggagaacagg
    18241 aatccagaaa ggatatggca gaagtatggc cgaacagtcc acagcttgaa attgataaaa
    18301 cagcagacaa atatgaatgg caggcaggag agcaggtagc ttaccggatc gtagtgaata
    18361 atgtaacggc aggaacaatc gcaaaagatg taactattac tgatattggt ctgccgcagg
    18421 gactggttct ggcaggtggt gcacagagca tggaagtact gggagttcag cgacaggtaa
    18481 actatcccgt accggataag aaaacaggac aggcatatga agcgagacct gtggattctc
    18541 agttgaatgc agatgagaac ggattttctt tttattgttc ttatgtacca tacagtcagc
    18601 ctgtaacgat tattttccat tgtatcgcac aggaagaggc aaatggacac gaaagcgtaa
    18661 atgcagcaac tgtaaaagct gctaatacag atgagagatc tgatgatgca gaagtatatg
    18721 taaattcagg agaattctgg attgagaaat ctgcagatca ttatgaatgg caggtcggag
    18781 aacaggtaca gtacaatgtg gtggtggaga ataaaaaagc aggtacagtg gcccggaacg
    18841 taactgtctg ggataccggt atgccggcag gacttgcgct ttcatcggca gaggatgtat
    18901 cggtaagcgg aatcccacag aatattacgc agctgacagc agggaccaaa gatgttttga
    18961 accagctcaa tccggaattt tataatgaga catcagagaa accggtgaat tatgaatttc
    19021 ttcaggaggg aagcggatgg agactgaaca tttcagatct tccggcaaat actccggtta
    19081 tgatttcttt cctttgcaca gttacggaag cggcaaatgg aatggaaagc attaatgttg
    19141 ccaatgtgca ggcgcagaat gcccctgttt cacaggatga cgcagaagtg tatgtaaata
    19201 cagcagttct ttctattgag aaaagttttc agaatccata tctggcagcc ggggacggac
    19261 gtgcggaaaa tgaatttcgg gtaggagaac aggtgaatta tcaggttacg gttaataatc
    19321 ttcagaaggg atctatcgca agaaatcttg tgatcagtga tctttccctt cctgaagggc
    19381 tggctctgga cggagctgaa gatgctgtta ctgtaagcgg tgttccggct gttattcaga
    19441 atccggtggc aggaactgat gatgcaggaa atcagctgaa tccggaaaat tataaagaaa
    19501 cagtggaaaa accggtcagc tgtcaggtta cacgtcaggg aaccggatgg atcgtgacga
    19561 tttcagatct tccgtatcag acacctgtga ctgttaattt ccgctgtact gcgcaggaaa
    19621 gcgtaaatgg gatggagatt gtaaatacag cacaggcgta tgcagataat gcacagaaag
    19681 taaaggactc ctcaaaaatc tgggtgaact cgcctgttct taaagtagag aagacgacgg
    19741 acaaaccatt ttacaaatat ggtgatatta ttacataccg cattgtcctg acacaggagc
    19801 agaccggatg tgtggcgcgt aatgttactt tgcaggatgt gatcgatact cagggagtac
    19861 gtcttctgaa ggattcggtg attctgatgg atgagaaagg aaatgtggca gatgctgatg
    19921 tacagatcaa tgatgataat actttcctga tgtcaacagg caggacactg gtcagggata
    19981 gtagatatag tatctgcgat aatgataaag gcggtctttt tgagcaggta atgtataatc
    20041 ctctggactg tcaggaacag aaaagtatga tcgtggaata tcaggcagca gtgattgatg
    20101 cagccctggc aggacagaaa gtgcacaata ctgcagttgc agacagcagt gaaaagatac
    20161 ctgcaaccgg ggaagcagag acagaggtac acagtccgat tctggaaatt gtgaaggaat
    20221 cagataagaa agagtatgcg tccggtgaaa aaggatatta taaactgaca gtaagacaac
    20281 tgcgtgagga tgtcacagat cagaatattg ttatcgaaga taaactggaa acccaagggg
    20341 cttccattgt aaaagacagc atttttgtga agaaaaacgg tatagaactg aaagatgcca
    20401 aaatagaggc agatgataca ggatttgtaa ttcagacagg agcatcgttg tcagatatgg
    20461 ataaaattga agtctgctat gaaatggtat ttaaaacaga aagcacagag cctgaaaaaa
    20521 ttgtaaacac agcgaaagca agaggtgata tttcaccgga aattactgca cagcaggagg
    20581 catatgtgaa agcaaaagca gaaccgactg ccacaccaac accgtctgta acaccgaaac
    20641 caacagaaac accaaagccg acagagacac caaaacctac agaagtaccg aaaccgacag
    20701 agcagccaaa agccacacca acaccatctg taccgggaac ctgcccgaaa atgactcctg
    20761 taccgacgaa agcaccgttg gcatcttaca atggtggaaa taatggagga acgacttccg
    20821 gaagcggagg cagcagttac gcaaattcgg gtggatattc cggtggatat ggaagctatc
    20881 agggtggttc catggcagga agttctaaaa caggagatgt cagaccgttt aaaatgatgg
    20941 ctgttcttgg acttatcgga atgggactgc tgacaggagg tgtggtgatc tacagaagaa
    21001 ctgtttccgg gaaaagaaat ataaagggta tgccgcggaa atgaaaaaac tcagaacatt
    21061 tgcagtaagt atgatcatag cagcaattgg gcttcttata tattgtgccg gcttctatat
    21121 aaaaagttat gaacagaatc ttgcagcaag gcaggaatat gcagagcttt cccaaatagc
    21181 aggggtgaag aacagagaag gtgccggatt attggcagat ggcaaaaaaa ctgatgaaga
    21241 cagcagtaca aaaaacagtg aaaaaaaacg caggaaaaaa cagagaagat cttctgaatc
    21301 aaaaaacaaa aactgtacag atgaaatcag ggaatccttc gggatttcct gggaaaattt
    21361 aagaaagatc aactctcaga cagttgcctg gattactgtc ccgggagccg atatttctta
    21421 tcctgtagtt caggcggcag atgatgaata ttacctgaaa cataatttca gaggagagga
    21481 agatctgttt ggatgtattt ttctggaaca tgacataaaa aagaatttta cagattccca
    21541 cagtattctt tacgggcata atatagaagg taatatgatg tttgcaaatc tgaaccgtta
    21601 tgaacggcct gaatttctga aaaaatgtcc tgaaattgag atcacaacac caaaaagaaa
    21661 gtttctgtac aaaatttttt ctgtggaaca ggcatcttcc aaaagcccgg catttgaata
    21721 tggatacaag ttatccagtc ctgcatacag gagacaatta tctatattga aaaataattc
    21781 catgtatgac acaggagtag agcctgatga aagggagaga atggtgactc tgatcacctg
    21841 taattcacgt ctggataaag aaatacgtat ggcggtacat gggatttgcc atgaatgtta
    21901 tggtatagaa aaagctgagc cgaagtgatg ttgaaatcaa tcggatattg gtaactttcg
    21961 taaaggatga actgttactg ttcacatatc actatccctc gaggtgtttt ggaaaaaact
    22021 aatgaaaaat ctctcaatat tttgtataat ttatgcataa aaaacaactt gttcgtacgt
    22081 gcgtacaagt tgtatcctaa atacaggagg gaagaagaca tgacagataa tggaaagccg
    22141 aaatatttct cactgatgga acagctcaga agtgatatta tgtcaggagc tatccgaccg
    22201 ggagagaagc ttccttcaga aaacgagctt tcacagaaat attccctgag tagacataca
    22261 gttcgtaaag cactgggaat cctggagcag gacggatatg tagaggcatt tcacggaaga
    22321 ggtacttatt gctctgagaa tatgcgccat ataaagaatt caaagaatat tgcggtagtg
    22381 accacatata tttctgatta tatttttccg agactgatac agggaatgga taatgtcctt
    22441 tcagaaagcg gttacagtat tatcctgaaa aacacagcaa acagcagaca gaaagaggcc
    22501 agatgtctgg aggaacttct gaagaaagac attgatggac tgatcattga accaagcaaa
    22561 agtgagatga tctgtaaaca cagaaatctt tatcagaatc tggataaatt tgaaattccg
    22621 tatgtgttta ttcagggaat ctattcagaa atgagagata aacctcatat tcttatggat
    22681 gatgcacagg gaggctatct tgtaacaaaa tatctgctgg aactgggaca taaaaagatc
    22741 aagggtttct ttaaggcaga cgatatgcag ggactggagc gccacaaggg atatgtgaag
    22801 gctttacagg agtcagggat tgcctatgat cctgatgatg ttgtctggtt tcatacagag
    22861 gacaggaaag taaaacctgc actgatggca aaagaaatgg tacagagcgg acagcttccg
    22921 gatggaatcg tctgttacaa tgatcagatt gctgttcagg ttatggaaga actggagaaa
    22981 atgggagtca ggataccgga tgatatttcc attaccggtt atgacaattc actgtatgct
    23041 cagcgaggaa gcggaatcac aacgatagct catccgcagg aaaagctggg agaaatggca
    23101 gcagagctta tacttgagaa gatcaacgga gttcctgaag aagaaagtaa ggttgaaaga
    23161 ctgatttatc cggaactgat catacgggga tcatgcagaa aaatattgta aacaaatgaa
    23221 ataaataaaa aataaatcca ggaggaatt
//
