LOCUS       c00055_NZ_LDYG..       14672 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LDYG01000055.1 Bacillus coahuilensis p1.1.43 ABFP000055, whole
            genome shotgun sequence.
ACCESSION   NZ_LDYG01000055
VERSION     NZ_LDYG01000055
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:33:34
            Original ID  :: NZ_LDYG01000055.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14672
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14672
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9753:10584](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(9754..10584)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..14672
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14672
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(281..2401)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_1"
                     /sec_met_domain="Fer4_8 (E-value: 2.1e-14, bitscore: 43.7,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.3e-05, bitscore: 13.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANILLISNWILFLLVTAYAFSLFVYVVRTRMEYIKLGKKPEFDN
                     NVKERMNKIWVNVFGQKKLLKDKKSGIIHVMFFYGFILVQFGAIDFIWKGLAPGSHLPL
                     GPLYPAFTFFQEIVTLMILIAVVWAFYRRYVEKLVRLKRGFKSGLVLIFIGGLMLSVLV
                     GNGMGLIWHGEELAWTEPIASGIAAAFGWVGETASIVVFYISWWIHLLFLLAFLVYVPQ
                     SKHAHLIAGPVNVYFNRIDNPGKLKSIDFEDESQESFGVGKITDFDQLQMIDFYACVEC
                     GRCTNMCPATGTGKMLSPMDLITKLRDHLTMHGAAVTSKQPWVPTFAFSGTKGNQIALA
                     SAGAGANEAAAAIEYAPSLIGDVITEEEIWACTTCRNCEDQCPVMNEHVDKIIDLRRYL
                     VLTEGKMDADAQRAMQNIERQGNPWGLNRKEKEAWRDLRDDVHIPTVKEMKKAGEEFDY
                     LFWVGSMGSFDNRSQKIALSFAKLLNEAGVKFAILGNKEKNSGDTPRRLGNEFLFQELA
                     ANNIAEFEKIEVKKIVTIDPHAYNIFKNEYSDFGFEGEVYHHTELLAELVKEGRLQPTH
                     EVNETITFHDSCYLGRYNEVYSPPRDILNAISGVKLVEMERNREKGMCCGAGGGLMWME
                     EDTGHRVNVARTEQALAVSPTVISSGCPFCLTMLSDGTKAKEVEETVATYDVAELLEKA
                     IFGEGPAETLVS"
     CDS             2630..3823
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_2"
                     /sec_met_domain="PLDc_2 (E-value: 1.4e-29, bitscore: 92.5,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLWILLLFVLFFTWIRLDFISGRAFHKRHTTHRDYPKRASDLQFI
                     ANGPELYDDVFDEMKQATSSIHILSYTFEPDEFGQEFMERLIEKAKEGLEVRLLFDRFG
                     SLKMKKKHVRHLREHGVYVAISQLPHFPFFFYTSQQRNHRKIMVMDGTTGYIGGYNIGK
                     QYVNQDCRLNPWRDYHLKVQGEGVKDLQREFLLDWKRATVDNLVENETYYPPLKEGRHV
                     LQYYPSDGNGLDQLFLSFIQRAYRSIVICTPYFIPTEEIETALVHALKRGVRVQILVPE
                     MKDHMLVKEAAYPHFRKLLPLGAEVYQFNKGFFHGKVFILDDELCDVGTANFDYRSFFL
                     NFELNTLIYDKTFINEVQSVIEQDMSSSTRLTIDELNSLSFLDRVKEMIARLVKYFL"
     CDS             3842..4804
                     /locus_tag="ctg55_3"
                     /transl_table=11
                     /translation="MRIRFGFVSNANALWDASPAQTVTYKRFTELGQEKGTEKLLEVTA
                     KNLRNTKRILYYLGAHDAHVYRMSSSLVPLATHPDVMWDFVTPFKQEWEELGRLVKELR
                     IRASFHPNQFTLFTSPREEVTANAIKDMDYHYKMLEAMGIVDQGVINIHIGGTYGDREA
                     AIGRFHENLKGLPFPIKEIMTLENDDKTYTVEETLEVCENESIPMVLDIHHHIANPTEA
                     PVESFLPRIFETWKHRDLPPKIHISSPKNKEEGNIRAHADYVDLDFILPLLKELKKLQQ
                     DVDFMIEAKEKDFAMLQLVEDVAGIRGVKRIDGAEIEWK"
     CDS             4879..5907
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_HSD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_4"
                     /sec_met_domain="Beta_HSD (E-value: 3.1e-28, bitscore:
                     88.3, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATVTVTGGTGYLASWIVRDLLKEGHDVRITVRNKDKIEKYQYLV
                     EFEKQYKGSLSVFEADLLQEGSFDEAVQGAEVVIHTASPFLISSDNPEKDLIQPAKQGT
                     RNVLTSVEKAPTVKRVVLTSSIVAIMGDNKEMAGREAFTENDWNTTSTSDHQPYPYSKT
                     LAEQEAWKMVKNQNQYDLVTINPSFIMGPTLSGRSDSTSISTIQQFLTGGFKTGVPKLY
                     SGIVDVRDVAKAHILAAFKPEAHGRYIVSSGEVTFLEIAKIIEKNFPGKYPLPKREVPK
                     ALIWLIAPSVGLTRKYVKENAGYRIAFDTTKSKQELGMTYRAIEATFVDQVDQMEEDGL
                     VK"
     CDS             complement(6220..6396)
                     /locus_tag="ctg55_5"
                     /transl_table=11
                     /translation="MGIKDVLLSLITGMIVGFLFAVFRLPIPAPPAFAGIMGIVGIYLG
                     FKLFEYVQPIIFK"
     CDS             complement(6499..8169)
                     /locus_tag="ctg55_6"
                     /transl_table=11
                     /translation="MNIVDQVQSKLKEEIKQAVIKAGLATEEQIPDVILETPKEKAHGD
                     YSTNMAMQLARVAKKAPRMIAEELTANFDRTKASIEKIEIAGPGFINFYMDNSYLTNLI
                     PVVLKAGEAYGESDAGEGQKINVEFVSANPTGDLHLGHARGAAVGDSLCNILDKAGFAV
                     TREYYINDAGNQIHNLAMSVEARYFQALGQEKPMPEDGYHGADIIGIAKQLADEFGDKY
                     VEVDEKERYDFFRSYGLKYELEKLKKDLEMFRVPFNVWYSETSLYENGKIDEALDVLKE
                     NGHVYEEEGATWFRSTTFGDDKDRVLIKNDGSYTYLTPDISYHEDKLKRGHDILINIWG
                     ADHHGYIPRMRAAIEALGYSPETLEVEIIQMVQLYKNGEKMKMSKRTGKAVTMRDLVDE
                     VGLDATRYFFAMRSADSHMDFDLDLAVSQSNENPVYYAQYAHARICSILRQADEQGVTF
                     NESANISLIKEEKEIDLLKKVGEFTGVVADSAKKRSPHRVVTYINELASAFHSFYNAAK
                     VLDDSNRELSEARLLLVRSVQITLQNALKLIGVSSPEKM"
     CDS             complement(8166..8600)
                     /locus_tag="ctg55_7"
                     /transl_table=11
                     /translation="VATTEITVRVDLSTTITQGEENETISFTTFGRYYEKAGSAYLRYD
                     EVLEEGTVKTTVKLSNEQGLILRGGAVKMRLAFNREDRMNGSYESPHGTFLLQTHTKEL
                     SHTETAEGEGTLRIRYELRMQGSSVGNYDMKITYKEELNQ"
     CDS             complement(8872..9741)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_8"
                     /sec_met_domain="Arginase (E-value: 1.2e-83, bitscore:
                     270.6, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFDEAYSGNVFIKSHPSYEESSVVLYGMPMDWTVSYRPGSRFGP
                     TRIREVSIGLEEYSAYLDRELEEVKYFDAGDIPLPFGNAGRSLEMIEDYIDGLLADGKT
                     PLGMGGEHLVSWPVMKAMAKKYPDLAIIHFDAHTDLREEYEGEPLSHSTPIRKIAEHIG
                     PKNVYSFGIRSGMKEEFQWAKENGMHISKFEVHEPLKKILPQLAGRPVYVTIDIDVLDP
                     AHAPGTGTVDAGGITSRELLASIHEIARSEVKVVGADLVEVAPIYDNSEQTANTASKLI
                     REMILGWM"
     CDS             complement(9754..10584)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_9"
                     /sec_met_domain="Spermine_synth (E-value: 1.3e-72,
                     bitscore: 233.0, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 1.2e-21,
                     bitscore: 66.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGGFWFTEKQTENFGITMKINRTLHTETTEFQHLEMAETAEWGNM
                     LFLDGMVMTSQRDEWVYHEMVAHVPLFTHPNPEKVLVVGGGDGGVIREVLKHPSVKKAV
                     LVEIDGKVIEYSKKYLPEIAGELENERVEVIVGDGFMHIAESQNEYDVIMVDSTEPVGP
                     AVNLFTKGFYAGISKALKEDGIFVAQTDNPWFKADLIQQVQRDVKEIFPITTLYIANIP
                     TYPSGMWTFTMGSKKHNPLEVAEDRFHEIDTKYYTKELHNAAFVLPKFVKDLTE"
     CDS             10826..12964
                     /locus_tag="ctg55_10"
                     /transl_table=11
                     /translation="MIDFCEKRGERMEIMPNFKGMNFSKTLKWLRALVILSIIVGLLLS
                     ITVLGILTYAKIQGAPTLAVPQSNLYYSSDGKIFGETHNGEKRYWVNLEDISPALIDAT
                     ISVEDKKFYDHLGFDLKRIAGAAVADIKAMSKVQGASTITQQYARNLYLTHDKTWSRKL
                     SEAMYSIRLELFYSKNDILEGYLNTIYYGHGAYGVEAASQYYFGKSASELTLGEATILA
                     GIPKAPSSYSPVADLEKATTRQTVVLDEMIEDGKITESQKSTALAEKPVIIGKHNLEVT
                     QTAPYFQDRVHYILQNQLGMTDRQIELGGLRIHTTLNVKHQEAAERLVKELIVDEGSKL
                     QVALTSMDPETGYVTAMVGGTDYVKSPFNRATQAIRQPGSTIKPLLYYAALESGFDPAT
                     TMKSELTSFRYNDGEDVYAPHNFNNRYSNNEITLAQAIGISDNVFAVKTHFFLGFDALI
                     DAGKQFGLSTPIGSEPSAPLGTSEVRVIDMVKAYSMFANGGRDIAPVFITKIEDPNGTI
                     LYEYENEGVQVLDPDQAFVMTDMLTGTFDPALNDHSSVTGSSVLDSVTRPYAAKTGSTL
                     WDRWMIGYSPQLVSGVWTGYDDNSEMTLAYDNTVAKELWVGFMEAALEDEEVAEFVPTE
                     NVVKVEVDPHTGKVATKDCPVTREMYFVAGTEPTEFCQTHIGEDRSIRDLLPGKKNGGD
                     SGSDSGKSLFDRVVDWIF"
     CDS             complement(13235..13744)
                     /locus_tag="ctg55_11"
                     /transl_table=11
                     /translation="MESEKKKKVGFNIIKNDPTDGHGGYGVGALSLENISPVFVDVEEK
                     DAFVDIGAMHARSSVEKGIKFTTNREDSEGGKPFWLVWVTIDRKETGPYYAGVTACELV
                     VNREKRRGYKVLPDHVNKMDKSLKRKIMVGEMDESSKTVLKEFLINHNEEFWNNSSEEL
                     KQSLSV"
     CDS             complement(13763..14428)
                     /locus_tag="ctg55_12"
                     /transl_table=11
                     /translation="LSIFSGDFLANLPFLVIALVIGFTVHEYAHAYVAYKFGDSTAAKQ
                     GRLTLNPASHLDPIGTILILIAGFGWARPVPVNRFNLRRPRLHSILVSVAGPLSNFVVA
                     FIATPFAILFMYFLGDSAVTTFFAQLFQTIVYLNVLLFVFNLIPLPPLDGYRIIEDLVS
                     PDIRAKMSQYEIYGPIIFIVLIVTPIGDYTIWPFLQGGIRTISVAFYTFYDSIFLLFL"
     CDS             14547..14672
                     /locus_tag="ctg55_13"
                     /transl_table=11
                     /translation="MPYVTVKMLEGRSEEQKRAMVEKVTEAVSETSGAPKDKIIRI"
ORIGIN
        1 ttctgcaccg cgccaggctc gcgcggcgct cttctccctt ccttctcccc ttttctgcac
       61 cgcgccgggc tcgcgcggcg ctcttcttgc ttcctctccc tcttttctac accgcgctcg
      121 gctcgcgcgg ggctcttctt gcttcctctc cctcttttct gcaccgcgcc gggctcgcgc
      181 acctcgctta tctttcagaa atgctattca tttaatcagc aaaaaaaggc acgatcacct
      241 aaatagtgat cgcgccttta attaaaaata actcaatgga ttatgacact aacgtttccg
      301 ccggtccttc tccaaatatt gctttttcta atagttctgc tacatcataa gtagccaccg
      361 tttcttccac ttcttttgct ttcgttccat ccgataacat ggttaagcag aatggacagc
      421 cagaagagat cacggttggg ctaacagcca gtgcttgctc agttcgtgct acgttcacgc
      481 ggtgacctgt gtcttcttcc atccacatta gtcccccacc ggctccacag cacattcctt
      541 tttcacgatt ccgttccatt tcaaccaact tcactccgct aatagcattt aagatatctc
      601 gaggcggtga gtacacttcg ttatatcgtc ctaagtagca ggagtcatgg aaggtgatgg
      661 tttcattcac ttcgtgagta ggctgcagtc gcccttcttt cacaagctcc gcaagaagtt
      721 ctgtatggtg atacacttct ccttcaaagc caaagtcgct gtattcattt ttaaaaatgt
      781 tgtaggcatg tggatcgatg gtgacgattt tctttacttc tattttttcg aattcagcaa
      841 tgttgttggc cgcaagctct tggaataaaa attcatttcc gagacgacgt ggtgtgtctc
      901 ctgagttctt ttctttgttt cctaagatgg caaacttcac gcccgcttcg ttaagaagtt
      961 tagcgaagga taaggcgatt ttttggctcc ggttatcgaa agagcccatt gagcctaccc
     1021 agaataagta atcaaattcc tcgcctgctt ttttcatttc tttcacagta gggatatgaa
     1081 catcgtctct gagatctctc cacgcttctt tttctttacg gtttagaccc caagggtttc
     1141 cttgacgctc gatgttttgc attgcgcgct gtgcatctgc atccatttta ccttctgtta
     1201 aaactaagta acgacgtagg tcgataattt tgtctacgtg ctcgttcata acaggacact
     1261 ggtcctcaca gttacggcaa gttgtacatg cccagatttc ttcttctgtg atcacgtcac
     1321 cgattaggct tggtgcgtat tcaatagcag ctgctgcttc gttcgctcct gcccctgcag
     1381 atgctagagc aatttggttc ccctttgttc ctgagaaggc aaacgttgga acccatggct
     1441 gcttagatgt aaccgcagca ccgtgcatgg ttaggtgatc gcgaagtttt gtgattaaat
     1501 ccataggtga tagcatttta cctgtacccg ttgctgggca catatttgta caccgaccac
     1561 actccacgca tgcgtagaag tcgatcattt gaagttgatc aaaatctgtt atcttgccga
     1621 ctccaaagga ttcttgtgac tcgtcttcaa agtcgattga ttttaattta ccaggattgt
     1681 ctattcgatt gaaatatacg ttcactggtc ctgcaattaa gtgagcgtgc ttagattgtg
     1741 gtacatacac taagaatgcc agtaagaata agaggtgaat ccaccaggag atatagaaca
     1801 ctacaatact tgctgtttct cctacccaac caaatgcagc tgcgattccg gatgcaatag
     1861 gctctgtcca cgccagctct tcaccatgcc agattaaccc catgccgttc cctactagta
     1921 cggataacat taagcctccg ataaagatca gaacaagtcc actcttaaat ccccttttca
     1981 agcgaacaag cttttccaca taacggcgat aaaatgccca cactactgcg attagaatca
     2041 tcagagtgac aatttcttgg aaaaaggtaa acgcaggata cagtggccct aatggaagat
     2101 gtgaaccagg tgctagtccc ttccaaatga aatcaatggc cccaaattga accaatataa
     2161 agccatagaa gaacataacg tggataatac cactcttctt atcctttaaa agtttctttt
     2221 ggccaaatac gttcacccaa attttattca tacgttcttt tacattgtta tcaaactctg
     2281 gtttttttcc aagcttgata tattccattc ttgtacgcac tacatataca aaaagactga
     2341 atgcgtaagc ggttacaagt agaaataaaa tccagttact aatcaataaa atgtttgcca
     2401 tgttaaccgt acactcccct caaagttgtc atgctttttc cccctttgcg tatagcaaaa
     2461 cttacaatat tcagaatgtt tctacctcca ttatataatg aatgagcatt cagtcaatat
     2521 gtttatccga tttcctacag attgtttgat ttagagagat tagggaaaat tgaataatgc
     2581 ctattttggg cacactatat ttactcgagg tgaaagaaag gagtccttta tgctgtggat
     2641 cttattattg ttcgttctat tttttacttg gattcgttta gattttataa gcgggcgagc
     2701 ctttcataag cgtcatacca ctcaccgaga ttatccgaag agagcttctg atttgcagtt
     2761 tattgcaaat ggcccagagc tttatgatga tgtttttgat gaaatgaaac aggctacctc
     2821 aagcattcac atacttagct atacgtttga acccgatgaa ttcggtcagg agtttatgga
     2881 aaggttaatc gagaaagcaa aagaaggatt agaagtcaga ttattatttg atcgatttgg
     2941 tagcttaaag atgaagaaga aacatgtacg tcacttgcga gagcacgggg tttacgttgc
     3001 catctcacaa ctccctcatt ttcccttttt cttttacact tcccagcagc gcaatcacag
     3061 aaaaattatg gtaatggacg gaacaactgg ctacattgga gggtataaca ttggaaagca
     3121 atatgtaaat caggattgca gattgaatcc ttggcgtgat tatcacctga aggttcaggg
     3181 agaaggagtg aaggatctac aaagagagtt cctgcttgat tggaaacgag cgactgtaga
     3241 caatttggta gagaacgaaa catactatcc tccgttaaaa gaaggcagac acgtactaca
     3301 atattatcct tctgatggga atggattaga tcagctcttt ctatccttta ttcagcgcgc
     3361 ataccgttcc attgtcatat gtacgcctta ttttattcca acagaagaga ttgaaacggc
     3421 cttagtacat gccttaaaaa gaggggtacg tgttcaaatt cttgttcctg aaatgaagga
     3481 tcatatgcta gtgaaagagg ctgcgtatcc tcattttcga aagctattgc cgctaggagc
     3541 tgaggtctat cagttcaaca aaggattttt tcacgggaaa gtgtttattt tagatgatga
     3601 actttgcgat gttgggacag ctaatttcga ttatcgaagc tttttcttga atttcgagtt
     3661 aaacacgctg atttatgata aaacgttcat taacgaggtt caatctgtaa ttgaacagga
     3721 tatgtctagt agtacgagac taacgataga tgaactgaat tctctgtcgt tcctcgaccg
     3781 agtaaaagaa atgatcgctc gtcttgtaaa gtattttctt taacaacagg aggtggttct
     3841 gatgcgaatt cgctttgggt ttgtgtcgaa cgcgaatgct ctttgggatg caagcccagc
     3901 tcagaccgtg acgtacaaac gatttactga actaggacaa gaaaaaggaa cggaaaagct
     3961 ccttgaagtg accgcaaaaa atttacgaaa cacgaagcga attctctatt atttaggcgc
     4021 tcatgatgca catgtgtata gaatgtcgag ctctctcgtc cccctcgcta cccatcccga
     4081 tgttatgtgg gattttgtca ctccttttaa acaggaatgg gaggaattag ggcgcctcgt
     4141 aaaagaatta cgcattcgtg caagttttca ccctaatcaa ttcacgttat ttacaagtcc
     4201 aagagaagaa gtaaccgcca atgcgatcaa agatatggac tatcattata aaatgcttga
     4261 agcgatggga atcgttgatc aaggagtcat caatattcat atcgggggaa cctatggtga
     4321 ccgagaggca gctataggtc gttttcacga aaatttaaaa ggtctccctt tcccaattaa
     4381 agaaatcatg acccttgaaa acgatgataa aacgtatacc gtagaagaaa ctctagaagt
     4441 gtgtgagaat gagagcattc cgatggtgtt agatattcac catcacatcg cgaatccaac
     4501 ggaagcacct gttgaatcgt ttttacctcg tatttttgag acgtggaagc accgtgacct
     4561 ccccccaaaa attcatatat cttctcctaa gaataaggaa gaaggaaata ttcgagcaca
     4621 cgccgattac gtcgacctcg actttatcct tcctttattg aaagagctga agaagcttca
     4681 acaggatgtg gactttatga tcgaggcaaa ggaaaaagac tttgctatgc tccaattagt
     4741 ggaggatgtg gctggaattc gaggcgtgaa acgaatagat ggtgcagaaa tcgagtggaa
     4801 gtgaatgttt aaaagcttaa actaagaaaa ataacgtcac ctgtggtacg atgaataaaa
     4861 aagaaagtag ggatgacaat ggcaaccgtt accgttacag gtggaacagg ctatcttgcc
     4921 tcttggattg ttcgtgacct tttaaaagaa ggacacgatg tacgtattac tgtccgaaac
     4981 aaagataaaa tagaaaaata tcaatactta gttgagtttg aaaaacaata taaagggtct
     5041 ctttccgttt ttgaagcgga ccttctacaa gaaggaagct ttgatgaggc cgtccaagga
     5101 gcggaggtcg ttattcatac agcttctcct ttcctcatca gttcagataa tcctgaaaaa
     5161 gatttaatac aacctgcaaa acaaggaact agaaatgtgc tgacttcagt tgaaaaagcc
     5221 cccactgtta aacgcgtggt cttaacgagc agcattgttg ccattatggg agataacaaa
     5281 gaaatggcag ggcgtgaggc attcacggag aatgattgga atacaacgag cacaagtgac
     5341 caccaacctt atccatactc taaaacgctc gctgagcaag aggcatggaa aatggtgaag
     5401 aatcaaaatc aatatgattt ggtcacgatt aacccgagct tcatcatggg acctactcta
     5461 tctggtcgca gtgactctac gagtatttct actattcagc aatttttaac aggtggtttt
     5521 aaaacaggcg taccaaagct ctattctggt atcgtagatg tgcgggatgt agccaaagct
     5581 catatccttg cagcgttcaa gcctgaggca catgggcgct atattgtctc aagtggtgaa
     5641 gtgaccttcc ttgaaattgc taagatcatt gaaaagaact tccctggtaa gtatccgctt
     5701 cctaagcgag aggttccaaa ggctttaatc tggcttattg cgccaagcgt tggcttgact
     5761 cgtaagtatg tcaaagaaaa tgcaggatat cgtattgctt ttgatacaac gaagagtaaa
     5821 caggagcttg gcatgacgta ccgggcaatt gaagcaacgt ttgtcgatca ggtggatcag
     5881 atggaagagg acggattagt caaataagga aatgaagctg ccccccactc tataggagta
     5941 gggggctttg ttttagatta ctttttttag atcaggtgat gaagtgggcg tgtggagtgg
     6001 agtagtcgaa tgcgtgggag atgtgctcgg tttgtgctgc tgagtgctcg aattcttggg
     6061 cgaagtgctc gaataactta aagtagtgct ttgattcatt ttgccaactc cccttgggcc
     6121 cttgactcca agaaaaattc catttagatc gcttgccctt tgaaagagag ctcaaacact
     6181 aaaaagaagg attcccgttt ggttacactc ctctatcatt cacttaaaaa taattggttg
     6241 tacgtactca aacaatttaa atcccaagta aatccccaca atccccatga ttcctgcgaa
     6301 tgcgggagga gcaggtattg gtagtctgaa cacggcaaag agaaatccaa cgatcattcc
     6361 tgtgatgagt gatagtagta catcttttat gcccatgaaa aacggccccc ttcattgctt
     6421 gttgaaggta gtgttcccat ttaatgaaga aatataaata agcgccggtt tcctagtgga
     6481 aatcggcgct ttcatctatt acattttctc tggagaagaa actccaatta atttcaatgc
     6541 attttgtagg gtgatctgta cagagcgaac gagtaggaga cgagcttctg aaagctcacg
     6601 gttcgaatcg tctagcactt tcgcagcatt atagaagctg tggaaagcag atgctaactc
     6661 gttgatgtac gtcaccacac ggtgtgggga acgtttctta gcagaatcag ctaccactcc
     6721 tgtgaattct cctacttttt tcagaaggtc gatttctttc tcttccttaa tgagtgaaat
     6781 gttggcactt tcgttaaatg ttactccttg ctcatctgct tgacgtagaa tggagcaaat
     6841 gcgagcgtgt gcgtattggg cgtaatagac agggttttca ttggactgag aaaccgctaa
     6901 gtctaggtcg aagtccatat gtgagtcggc tgaacgcatt gcaaagaaat agcgagttgc
     6961 gtcaagtcct acttcgtcta cgagatcacg catcgtaacg gctttaccgg tacgcttact
     7021 catcttcatt ttttcaccgt ttttatagag ctgaaccatt tgaataattt ctacttccaa
     7081 agtttcagga gaatatccaa gtgcttcaat ggctgctctc attctaggaa tatatccgtg
     7141 atggtctgct ccccaaatgt tgattaaaat atcatgtccg cgttttagtt tatcctcgtg
     7201 gtacgaaata tctggtgtca aataagtgta agagccatca tttttgatta atacacggtc
     7261 cttgtcgtca ccaaatgttg tggagcggaa ccaagttgct ccctcttcct catatacatg
     7321 tccgttctct tttaatacat caagagcctc atcaattttt ccattttcat agagagaagt
     7381 ttccgagtac cacacgttaa atgggacacg gaacatttca aggtccttct ttagtttttc
     7441 aagctcatat tttaacccgt atgaacggaa gaagtcgtag cgctctttct catcaacttc
     7501 cacgtatttg tccccaaact cgtctgcaag ctgctttgca attccgataa tatctgcccc
     7561 gtggtagccg tcttctggca ttggcttttc ctgtccaaga gcttggaagt aacgagcttc
     7621 tacactcatt gctagattgt ggatttggtt ccctgcatcg ttaatatagt actcgcgtgt
     7681 aacagcaaaa cctgctttgt ccaaaatgtt acatagtgaa tcacccactg cagccccgcg
     7741 cgcatgccct aggtgaagat ctcctgttgg gtttgctgat acgaactcga cattaatctt
     7801 ttgcccttca ccagcatctg actctccgta agcttcgcct gctttaagca ccactggaat
     7861 taaatttgtt aggtagctgt tgtccatata aaagttaata aaaccaggac cagcgatttc
     7921 gattttctca atcgaagctt tcgtgcggtc gaagttggct gttaattcct ctgcaatcat
     7981 acgtggtgct ttttttgcaa cgcgcgctag ctgcatcgcc atgtttgtag agtaatctcc
     8041 atgcgctttt tcctttggtg tttctaaaat aacgtctgga atttgctcct ctgtcgcaag
     8101 tcctgccttg ataacggctt gtttaatttc ttcttttagc ttactttgta cctgatccac
     8161 tatattcatt ggttcagctc ctccttgtat gtaatcttca tatcataatt accgacagag
     8221 ctcccttgca tacgaagttc atagcgaatt cgtagggtgc cttctccttc ggctgtttct
     8281 gtatgggaaa gttcttttgt atgggtttga agtaaaaacg taccgtgggg actttcatag
     8341 gacccgttca tccgatcttc tcggttaaac gctagtctca ttttcaccgc tcccccgcgc
     8401 aggatgagtc cctgctcgtt cgataattta acggtggtct ttactgttcc ttcttctaac
     8461 acctcgtcat accggagata tgcgcttcct gccttctcat agtatcgacc aaatgttgta
     8521 aatgaaatcg tttcgttttc ctcgccttga gtgatcgtcg tggatagatc cacacgcacc
     8581 gtgatttctg tagtcgccac gctccgacac ttcctttaat taaaagttcc ttataactaa
     8641 ttaagtataa gaataatgaa gggaaaatgc aacggatgaa gggagtttta aaagaacaat
     8701 catgagagca ctttcttccg tgcagtcata caagaccagc tactctaagt atttttcatc
     8761 cttctaaatc tgcctttgtc ctatagtacc taggtgcttt tgctaagaag aaattttatc
     8821 gttcctcatg aaaaaacagc acctactgaa cataggtgct gtccctttat cttacatcca
     8881 accaagaatc atttcgcgga tgagtttgct tgctgtattg gctgtttgct cggagttatc
     8941 ataaattggt gccacttcaa ctaaatctgc tccaactact ttcacttctg agcgagcgat
     9001 ttcatggatg gatgctagta gttcacgaga tgttattcca cctgcgtcca ccgttcctgt
     9061 tcctggtgca tgagctgggt ctagaacgtc aatatcaatc gtaacgtata ctggacgtcc
     9121 agctagctgt ggaaggattt tcttcagtgg ttcatgtacc tcaaactttg agatgtgcat
     9181 gccattttct tttgcccatt ggaactcttc cttcatacca gaacggattc caaaggagta
     9241 cacattttta ggaccaatat gctccgcaat tttacgaata ggtgtagagt gagaaagtgg
     9301 ctctccttca tactcttcac gtaggtctgt gtgagcatcg aaatgaataa tcgcaaggtc
     9361 agggtatttc ttcgccatag ctttcatcac aggccacgaa actaaatgct ctccgcccat
     9421 accaagtggc gtttttccgt ctgctaaaag accatcaata tagtcttcaa tcatctctaa
     9481 gcttcgccct gcgtttccga atggtaaagg aatatcacct gcgtcaaagt atttgacttc
     9541 ttctagctca cggtctaaat acgcgctgta ttcttcaaga ccgatcgata cttcacgaat
     9601 acgagttggg ccaaagcgag aacctggtcg gtagcttacc gtccagtcca ttggcatacc
     9661 atatagaacg accgaactct cctcgtacga aggatgactt ttaataaata cattccctga
     9721 ataagcttca tcaaagcgca tagtggtgcc tccttattct gttaagtctt taacgaactt
     9781 cggcagaacg aatgctgcgt tgtgaagctc ttttgtgtag tactttgtat cgatttcatg
     9841 gaagcgatct tccgctactt caagtggatt gtgctttttt gaacccattg tgaaggtcca
     9901 cataccagat gggtacgtag ggatgttggc aatatataac gttgtaattg ggaaaatttc
     9961 ttttacatca cgctgtactt gttggattaa atctgcttta aaccaagggt tgtccgtttg
    10021 cgcaacaaag attccatctt cctttagtgc tttagaaatc cctgcataga agcctttcgt
    10081 aaataggttc acagctggtc caactggctc agtagaatct accatgatta catcgtattc
    10141 gttttgtgat tcagcgatgt gcatgaagcc atcgccgaca atcacttcta cacgctcatt
    10201 ttcaagctct cccgcaatct caggaaggta ctttttagag tactcaatga cttttccgtc
    10261 aatttcaact aacacggctt tcttcacgct tgggtgtttt aacacttcac ggattacacc
    10321 gccgtctcct ccacctacga ctaatacctt ctcagggtta gggtgcgtaa ataatggaac
    10381 gtgtgcgacc atttcgtgat agacccactc atctctttgg cttgtcatga ccattccatc
    10441 aaggaatagc atgttgcccc actctgctgt ttcagccatt tctaaatgtt gaaactctgt
    10501 tgtctccgta tgtaaagtac gattaatttt catcgtaatc ccaaagttct ctgtttgctt
    10561 ttctgtaaac cagaatccac ccactaaaat caatcctttc cacgattaaa tgtattggaa
    10621 cgaaagaagt ctttcgtatt tgaacgtatc agttgaaaga ggagccgtca aatgattgca
    10681 tcgtttgtag ctttccctaa caatgtaaat acaaacatga gaaaagtata gtcgaatgac
    10741 gggaaatatc aagaaaaatt ttctactatt tttcagttct tgtataaaat atagatttgg
    10801 cccccatact agaggctata atagtatgat agatttttgt gaaaaaaggg gtgagagaat
    10861 ggagattatg ccgaatttta agggaatgaa tttttctaaa acgctgaaat ggctgcgagc
    10921 acttgtgatt ctttcaatta tagtggggtt gcttctctct attaccgtgc ttggcatttt
    10981 gacgtatgcg aaaatccaag gggctcctac tctagctgtt ccccagtcca atctctacta
    11041 ttcctctgat gggaagatat tcggagaaac gcataatggg gaaaaacgct attgggtcaa
    11101 ccttgaggac atatcacccg ctttaatcga tgcgaccata tcagtagaag acaaaaagtt
    11161 ctacgaccat cttggctttg atttaaagcg gattgccggg gcagctgttg cggacattaa
    11221 agcgatgtct aaagttcaag gagccagtac cattacacag cagtatgctc gtaatttgta
    11281 tttaacccat gataaaacgt ggtcgagaaa attatctgaa gccatgtata gcataaggct
    11341 tgagctattt tatagtaaaa atgatatttt agaaggttac ttaaatacca tctattatgg
    11401 tcacggagct tacggagtgg aagccgccag tcagtattat tttggcaaat cggcgagtga
    11461 gttgacgtta ggggaagcga caattttagc aggaattcca aaagcgccta gctcctactc
    11521 ccctgtcgca gatttagaga aagccacaac tcggcaaacc gttgtattag atgaaatgat
    11581 agaagacgga aagatcacag agtctcagaa aagcacagca ctagcggaga agcctgtaat
    11641 tattggaaaa cataacctag aagtgacgca aacggctcct tatttccaag accgagtgca
    11701 ctatatttta caaaatcagt taggcatgac agaccgccaa attgaacttg gtggcttgcg
    11761 tattcacacg acgctcaatg tgaagcatca ggaagccgct gagagattag taaaagaatt
    11821 gattgtcgat gaagggtcta agcttcaggt tgcccttact tcaatggatc cagaaacggg
    11881 atatgtgacc gcgatggtgg gaggaaccga ctatgtgaaa agtcctttta accgcgctac
    11941 acaagcgata cgacagcctg gttcgacgat taagccgtta ttgtattatg ctgcgttaga
    12001 gtcaggattt gatcctgcga ccacgatgaa aagtgagctc acaagcttcc ggtataatga
    12061 cggagaggat gtgtacgctc cgcataattt caacaatcgg tacagcaata atgaaattac
    12121 actagctcaa gcgataggca tatcggataa cgtatttgca gtcaaaacac actttttctt
    12181 aggctttgat gcgttaatag atgcgggaaa gcagttcggt ctttccacac ctattggctc
    12241 ggagccttca gcacctcttg gtacaagtga agttcgagtg atcgacatgg tgaaagctta
    12301 tagcatgttt gctaacggag gtcgtgacat tgcaccagta tttatcacca aaattgaaga
    12361 cccaaatggg actattctct atgaatatga aaatgaaggg gttcaggtat tagatcctga
    12421 ccaagccttt gtaatgaccg atatgctcac tgggacattt gatcctgctt taaacgatca
    12481 ttcgtctgta actggatcga gcgttttaga ttcggttact cgcccgtatg cagcgaaaac
    12541 gggttctact ttatgggacc gatggatgat tgggtattcc cctcagctcg tatctggcgt
    12601 gtggactggt tatgacgaca attctgaaat gacgcttgcc tatgacaata ctgtcgcaaa
    12661 agaactgtgg gttgggttta tggaagctgc ccttgaagat gaagaagtgg ccgagtttgt
    12721 ccctactgaa aatgtggtca aagtggaagt agatccacac acaggaaagg ttgcaacgaa
    12781 ggattgtcct gtgacccgtg aaatgtattt tgtcgctggg accgagccaa cagagttttg
    12841 ccaaacccat attggcgagg atcgatctat tcgcgacctt cttcctggta aaaagaacgg
    12901 cggtgacagt ggctcagata gtggaaaatc actatttgat cgagttgtgg attggatttt
    12961 ttaatacatg tgagcgggaa ggcttggggc ctttcctctt tttatttgag ggttttttga
    13021 ccgctgatgt ttaaaaattt caatcgacgg ttccttacct aaaaatagac atgaaaaaac
    13081 tcgagcttgt ccagagcccg agttctttca tgtcctagtt ccatcttgtg cgagatgtga
    13141 ctttagttta ctcccattcg ctcataagag caatatgtga agaaaatttt caaaaaactg
    13201 tcataaatta ttcacagttt tcccagtttc tttcctaaac tgaaagactt tgcttgagtt
    13261 cttcagagga gttgttccag aattcttcat tgtggttgat cagaaattct ttaagcaccg
    13321 ttttggagct ttcatccatc tcgcctacca ttatttttcg ttttaggctt ttgtccattt
    13381 tgtttacatg gtctggtaat accttatagc ctcggcgttt ttcacggttg acgactaatt
    13441 cacaggccgt tactcctgcg tagtatggtc ctgtttcttt tcgatcaatg gttacccata
    13501 caagccaaaa aggtttccca ccttctgaat cctctcggtt tgttgtgaat ttgattcctt
    13561 tttctacact gctgcgagca tgcatcgcac cgatgtcgac aaatgcatcc ttttcttcaa
    13621 cgtctacgaa gacaggtgag atattttcca agcttaaagc accgaccccg tatccaccgt
    13681 ggccgtctgt tgggtcgttc ttgatgatat taaagcccac ttttttcttt ttttctgatt
    13741 ccatttgtgt tcctccttta ttttataaaa agagtaaaaa gatcgagtcg tagaatgtgt
    13801 agaatgctac agaaatcgtt ctaattccac cttgtaaaaa tggccaaatt gtataatcgc
    13861 caattggtgt tacgatcagt acgataaaaa taatcggacc ataaatttcg tattgtgaca
    13921 tttttgctcg tatatctgga gaaactaaat cttcaataat tctgtatcca tctagtggtg
    13981 gtagaggaat taagttaaag acaaacaata atacattcaa atagacgatg gtttgaaaca
    14041 attgagcaaa gaacgttgta actgctgaat ctcctagaaa atacataaac aatatcgcaa
    14101 acggcgtcgc aataaatgca acaacaaagt tacttagcgg tcctgctaca gatactaaaa
    14161 tactatgtaa tcgcggtctt ctcaaattaa aacggttaac aggaactggt ctagcccaac
    14221 caaagcctgc aattaagatt aaaatggttc cgattggatc caagtgagat gctggattta
    14281 aggttagtct tccttgtttt gctgcggttg agtctccaaa tttataggct acataggcat
    14341 gagcatactc atgaaccgtg aagcctatta ctagagcaat cacgagaaat ggaagattcg
    14401 ctaaaaaatc gccactaaaa atactcaagt gatcacactc ctctctcttc ttttttattt
    14461 tgcatttatc ctgtagaaca tactattcta aaagaagtaa acgttatacg tattgtatca
    14521 aataacccgt gacggaggaa tgcataatgc cttatgtaac agtaaaaatg ctagagggtc
    14581 gctcagaaga acaaaaacga gcaatggttg agaaggtaac cgaggccgta agtgaaacat
    14641 ctggggctcc gaaggataaa attatccgaa tt
//
