LOCUS       c00001_NZ_DAJP..       23228 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_DAJPGC010000001.1 MAG: Ruminococcus bromii isolate VEG01_HAM_0002
            s102.ctg000156c, whole genome shotgun sequence.
ACCESSION   c00001_NZ_DAJP..
VERSION     c00001_NZ_DAJP..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:46:04
            Original ID  :: NZ_DAJPGC010000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2086285
            Orig. end    :: 2109513
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23228
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2096285:2099513]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13228
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23228
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23228
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="3"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1398..1883)
                     /locus_tag="ctg1_1902"
                     /transl_table=11
                     /translation="MIKINIICIGKIKEKYFTDAIAEYAKRLTAFCKFNIIELSEERIK
                     SNIPNRSQIDEVIFSEGKRIMQKISPSDYVVAMCIEGKSMSSEELSRLIDNASVSGKST
                     VDFIIGGSYGLDESVKKRADVRLSMSRMTFPHQMARMILSEQIYRAFEISSNGKYHK"
     CDS             complement(1905..2693)
                     /locus_tag="ctg1_1903"
                     /transl_table=11
                     /translation="LARAVPLFSGSKGNSYYIGSASEGVLIDAGRSCKQIENAMLANGL
                     DMGSVGAVFITHEHTDHCSALRVLAKRYGFKVYSSLGTLNALRAGNKLDPNTDADVITD
                     EVVIGNMRVQRIDTPHDAAESCCYRVTAPDGKSALIATDMGIMLPDVRTAAEQSDFVVL
                     ESNHDINMLKNGFYPYPLKQRILSNRGHLSNEACAKELVNLVEKGTLRLMLGHLSEENN
                     TVPLAMSTSVDLLTSNGMKYKSDYSLDVAPSVSTTKAIIF"
     CDS             complement(2816..4108)
                     /locus_tag="ctg1_1904"
                     /transl_table=11
                     /translation="LEKFVVTGGKPLSGEVTISGAKNAAVAIIPAVILCDEPCQIENIP
                     NISDVSLISRILQQMGANVRRINRSSLYIDPTKIRTCNAVTDLVRGMRASYYLLGALLG
                     KYGKAKVALPGGCNFGVRPIDQHLKGFEALGATTQLVDGAIIEAECDSLVGTHVYLDVV
                     SVGATMNIMLAASKAKGQTIIENAAREPHIVDLANFLNSMGADVRGAGTDVIKIRGVEY
                     LHGITYSIIPDQIEAGTYMCAAAATRGCITVKNITPKHLESISAKLREMGVKITEYDEA
                     LKVDASSAPLKRCNIKTMPHPGFPTDCQPQFAALLMSVPGTSIINENVWDNRYQYVSEL
                     IRMGAQISVEGRLAIIEGGVPLTAAPVKATDLRAGAAMIIAALEINGTTEISNIQFIER
                     GYEDVVEKFRGLGADIKKVYFTGDNEQELGA"
     CDS             4791..5507
                     /locus_tag="ctg1_1905"
                     /transl_table=11
                     /translation="MSETAKEPKKISKRSSEEKIEIIVAIFLGITALATAWASWIGSLH
                     GGNQATNYTKSNNLSSEGNSMWNEASQNLMQDMITWNDINEANLNYQYAESKNDKAEME
                     KYQYQIDQLMSDNCTEEFLEAINWAMDQKENVTPFMKDGYTESYFAEAQATIEESDKLL
                     EQGKKDNANGDAFGLVSVIYSVVLFMLGIVGTFKNLPNRRIVLGVAVAGFILATIYMFT
                     IPMPTGFNILSYFGMA"
     CDS             5711..6028
                     /locus_tag="ctg1_1906"
                     /transl_table=11
                     /translation="MENKEKTTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALSMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
     CDS             6041..8365
                     /locus_tag="ctg1_1907"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCAHCAGKIEAKIAETNGFEDVSFNFATKLLNFKS
                     EKQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLNCAHCAGKIEAKITETDG
                     FEDVSFNFATKLLNFKSEKQNPISEIQSICDSIEDGVTVVDKTPKNDITTKAEPEITKK
                     KINHDTIFLAISIVLAVVSEILHLTLDGVTAIHYVVLAACFVATLLSGYKVFIKGAKNI
                     LKLRIDETTLMSVAVIAAFCLGDFVEAAMVTILFSIGEIFEDRAVDASRRDIEKLANIR
                     PDTATIIVDGAEQIVPAESVEIGSIIEVKPYERVPLDGIIIKGKTTLDTSALTGESLPV
                     DAGEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDAAAQKGNSEKLISRFASV
                     YTPVVVLIAVAIAVIPPLCGLGAFSEWLYRALVCLVASCPCAIVISVPLSYYSGIGAAS
                     EVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTVGSYSADEVLALAAASEK
                     YSAHPIASAIRERANGLELPELSDYSESAGHGTSAVYNGKTIQCGGSKILSDEQKKIAN
                     KDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLKVLGVKNTVMLTGDRQQPAENVKNE
                     LGLSEYHAELLPAQKLELFKGLKSKSKGACFVGDGINDAPVLSASDCGIAMGFGSEAAI
                     EASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKALVIILAAFGLAQIWMSVI
                     ADTGVSVVCVLIAARLLKKKY"
     CDS             8563..9804
                     /locus_tag="ctg1_1908"
                     /transl_table=11
                     /translation="LKKIFLLLVTALFLLSLYGCNTSSSSNNPTEQTTVTNTDDLSLDT
                     DTDTDSETEFNYDLEIYNNDKKIDTLNLFDALMPTEDGLIYSKINETSPNEIEYYRYYL
                     DKKSSIKLGSIKDWTMQINDKAYVNNHLCFMASTGDITDEENRTLEFIDIDLNKNKMTT
                     VFSDKGGFPYDTVTGADNLVIITKVLNNGTSLELYDTETQKFKQLKYLEFDDKNCVGKT
                     IRKVSIDDKTKTICLLVLDCVSETDVSLRIETYDYDMNFLKSYDISNISDDSNELIQGV
                     QFFDFRNNYLIYQNFSMTRCIGYIGNKKLQKSDMIDNIDDTYSMAQTPQKGYNTVLSFK
                     DVDLERNIYLFNTIDKTMKKTKFKPEEENYYIGSMLRTGKDNLMIITTPDNADKKSNLN
                     PKLYFTKLSDLNFQ"
     CDS             10001..11623
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1909"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.6e-41, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             11636..12127
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1910"
                     /sec_met_domain="ALS_ss_C (E-value: 2.9e-28, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             12188..13228
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1911"
                     /sec_met_domain="IlvN (E-value: 2.2e-81, bitscore: 268.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1e-58, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCINPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(13403..15544)
                     /locus_tag="ctg1_1912"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKILKAESVYGGVKLTWNKVNGAAKYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGKSVKYIAAPEISKLENVNGGVKITWNKVNGASKYRI
                     YQKNSSDWFRVSDTTSNSIVDKSVDVGTYTYTVRCISDDGKSFESGFNPKGSSIRYNQA
                     PKILETNVVNGGIKVIWETENNTNYRLYCKTEGKGWTKVCDNKTGVVTHKNLQPNKTYT
                     YTVRAISSDAKKYLSGYDPVGMSAKYVATPKISKAEYTYDGIKLAWNKVAGAEKYRVYY
                     KDGEGWNKLADTTGNSYLDMGLVSRELSIKDNSVNGQYIYTVRCISSNGKVFQSGYDTK
                     GSKANLGNECPEIVRVDSMHGGITVSWTDVCEDNSKYRIYVKEKGSWKKLADTTNNYYT
                     HKNVKAGQTYTYTVRCVSKDGKKFTSIYNPSGVTFKYKTTDKTRDAYIDYLLKHESEWL
                     PELKVGNVALAGVQFADLDFDGVPELIVQEAGDKEYYLNAKVYTFKDGKFSLVGFDDYR
                     TYIPNQLTYFYDKSAKKYIINAVELSTSNVDRYLERENYTLNYDGTVLVVRGYSSAHLA
                     LESRGLEYHYYNNTGRTTKQAYNATNVSVLGNCVNAHMYSQFVYCSVDGYPKLWNQFTT
                     DQKRQYLTDSYNAFSYDKY"
     CDS             complement(15741..16763)
                     /locus_tag="ctg1_1913"
                     /transl_table=11
                     /translation="MKKFLTALIAFVMCFSVVTTAFAATPDETSDSDLISDIKQAMLDT
                     YYGDEKPDFIEVRIYGTASDGGVYFDFMDSFTHWTDEVKFDLGNYTISYPRDCPVLLYK
                     NNKVYTLSDAYETGVIDDDMLYELYVWGNLWGKIDVTPKGEDRALLSEIKRVIINKYYN
                     GKAPEYLNVEIVGSTSDETVCFRNIPFMSLGVMIEQTIGDYTYYYNHGDDVMLYKNGNV
                     YSIKEAYESGVIDDSILEELSKMNFGLESNKPNTTVPTEPTTSVATVDEPVTVPDTTSA
                     TSTTKPVSTSDTATNDTPNNSQNNSGAVQTGQNSVAVILLVAMLAGCAVIFAKRRNYFK
                     "
     CDS             complement(16957..17634)
                     /locus_tag="ctg1_1914"
                     /transl_table=11
                     /translation="MKKLLTALIAFVMCFSVVTTAFAATPDEISESDVASEIRQVMIDT
                     YYGGKEPEYLNIEIVGSTSDGGVYFMHNEGFSLDYSIEETIGDYTYHYNHNDDVMLYKN
                     GNVYSIKEAYESGVIDDSILEELSKMNFGLESNKPNTTVPTEPTTTVATVDEPVTVPDT
                     TSATSATKPVSTSDTATNDTPNNSQNNSGAVQTGQNSVAVILLVAMLAGCAVIFAKRRN
                     YFE"
     CDS             complement(17829..19232)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PYC_OADA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1915"
                     /sec_met_domain="HMGL-like (E-value: 1.6e-47, bitscore:
                     159.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 2.3e-53, bitscore:
                     177.9, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKIRVTETALRDAHQSLIATRMTTEEMLPVLDKLDKIGYYSLE
                     CWGGATYDSCLRFLNEDPWDRLRTIREHCPNTKLQMLFRGQNMLGYRHYADDCVEYLVQ
                     RSIANGIDIIRIFDALNDIKNLKTAIKAANKEGGHAQVAISYTTGPVFTDEYYVEYAKR
                     IADAGADSICIKDMAALLTPTRTESLVKAIKAAVPELPLQLHTHYTSGLASMCLLKGVE
                     AGADGIDTAISPLALGTSHAPTESMVAALSGTEFDTGLDLKQFSDIRAYFMTLREKYIK
                     SGLLDPKMLATDANALIYQVPGGMLSNLLSQLKQAGKEDKLDEVLAEVPRVRKDSGYPP
                     LVTPTSQIVGTQAVFNVITGKRYSMCTNEFKGLVAGEYGTTPMPIDREFQKKIIGDKKI
                     IKGRPADQLEPELDKLRGEIEQWIEQPEDVLSYAQFPKVALDFFEKRRNAKVGINGDKL
                     DKKNMVHPV"
     CDS             complement(19263..19628)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.7; E-value:
                     8.2e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1916"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.8e-19, bitscore:
                     65.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRITVNGTAYDVQVEELGGSSAPAAAAPAPAAAPAPAAKPAA
                     PAGAQGSVVVKAPMPGTVVNVVVSAGQAVKAGDDLVFIEAMKMETPVKAPQDGTVATVD
                     VAKGESVDSGKVLVTLN"
     CDS             complement(19667..20980)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CT_Btheta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1917"
                     /sec_met_domain="CT_Btheta (E-value: 1.8e-65, bitscore:
                     218.4, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIEKINQAKAEIAATSAYKTITAFFDADSFCEIDAFAKSGEGFA
                     EVVAGFGTVEGMPVYAFAQNSDICGGAMSKAQAAKLKKLYGLALKTGAPVVGFYDSVGG
                     RLNQGTELLAGCGDVLNAAASLSGVVPQISVVLGTCLGTNALNAASADIVIMSKDAQLS
                     LSVTGKHSDAAYNAENGIASIVCDDADKAIKAAKELILYLPSNNLTMAPQSFEEAPAED
                     GCGCVVSRTVDGNSIVKLFNDYGKEANVRFARLGGQVVGIVVTKGKELGCKSANKVAKF
                     VRFCDAFSLPVVTFVNCPGFESIKSATKASAAYAEATTVKISVVTGKAIGSGYVALAGT
                     GANADVVYALPDAVISPVNVEAAAFIMAPEVMNVATDKQAEVAQKFADENLSAYNAAQN
                     GYVDGIVEEAQLRQTLISALDMLSGKRVSTLSKKHSTI"
     CDS             complement(21210..21959)
                     /locus_tag="ctg1_1918"
                     /transl_table=11
                     /translation="MAKIEPIRLQKFIAQCGIASRRKAEELILGGHVKVNGKTAILGDK
                     VLPTDKVFVRGKRIVVPKGGNYRYIMLNKPRGFITTMNDERGRKCVAQLVENVGERVYP
                     IGRLDKDSEGMLVFTNDGDFANKVMHPKNNVYKIYRVTVRPSIDEDQLVKLETGVELDG
                     RKTAPAYVHVIHKEQGRVVLEMILHEGKNREIRRMCEAVGLEVARLKRTQIGGVKMGML
                     KQGDWRDLTEQEVKKLLANPFLNGKQL"
     CDS             complement(22003..23127)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1919"
                     /sec_met_domain="Peptidase_S11 (E-value: 5.7e-57, bitscore:
                     189.9, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIISLAVCFVMPFVLMGAKTAEDTPPTTSAQAFVLYCPDNNTV
                     ICSKNADERMKPASTTKIMTSLITLEEAASCNSEVTFKQEMVAEGSSMYLKVGEKVRLS
                     DLASGMMMASGNDAANAAAYTISGSPEKFSQRMNEKAKQIGMTNTNFVTPSGLDDDNHY
                     SSAKDMALLMSYALENDDFANLTAKKSVTVEFLEPKSKKTAYANHNRLLSLYPYCTGGK
                     TGYTTAAGRCLVSSAKKDGVTLVCVTLNDRNDWNDHISLYDYAFEKYRGVDCKDADFCA
                     DIPCVGGDKDSVTVTGEKNNTIVLKREDCDKIKKKIFIDSFLYAPIEKNESVGRIEYTL
                     GGKLLYKCNIVAGEKIKSDKKSVSIFSAIGNLFS"
ORIGIN
        1 tggcggcaaa gttgtctgac ggggcttttt gcccttttga accttgagat agccctgctc
       61 ggtaagttcc tcacgaattt gcgcaaggtc tttttcattc tccgcacggt caaccgtatc
      121 gagaaccgag ttaatataat caagctcttc cctgcccttt tcaagctgtt ctttgagcat
      181 aatttcggca tttttagcct tgcggtaatc cttgtaatac ttctgagcat ttgccgaagg
      241 tgagattgcc ggattaagct ttatgcgtaa aattgcgttg ttctcatcgt aaaagttttc
      301 aacatcaaca tactccgcac cacgctcaat gcgatagata tttgcctgta aaaggtcacc
      361 gcatatgcga agatgctcac ggtctgcaca gcgttcaagc tcactcttct gctttgcaat
      421 ttttcgtgca agcctttcaa gtgtgttgtt caaaagcttt gtaaggcttt gtgatttcac
      481 cctcattctg tcacgactgt cacgagcctc atagaatccg tcaagcaaat cggagaagct
      541 ttccttactc tcaacctttg caaaatcgcc gtactgctca acattcataa agcaaaagtc
      601 cataggcttt ccgtcctcac gataaaccac aacaggcttg cccgaacaat cgctgcaaac
      661 gcttttcagc ttttcgattt caactgcgag tcggtcaaaa agcacaccct caattctgtt
      721 tgttgtgccc tccataacct tgtattcaat ctcacggcat acaatcggag aaacgccctc
      781 aattgtcctt aacagcgcct tgttaagcgg catttccgtg tcaagatttt ttacggctgt
      841 acacacatca agcaccgaac atttaagcag attcagcttg ttctgcgatt cgggaagttc
      901 gtattttata ttcggcagta caagtctttt actgctcatt gtaagatcta cacgcttgag
      961 cgaatcgatg atgacgccgt ttgaatcgac aataattatg ttgctgtaca tacccataat
     1021 ttcgcataca acagttatca tcacagtatc gccgagttcg ttcacgcact cgaaatcgag
     1081 cataagaaca cggtcgcaac cgttctggcg aagtcccaca agctttccgc cgccgattct
     1141 ttttcgcaaa agcatacaga acatcggagg ttgtgcagga ttttcgggtg ttgacgaaca
     1201 gaagttcact ctcggtgaat ttgctcgtgc agaaagcaac agctttttgt tgccggaaaa
     1261 tgttctcaac ccgaacacaa gctcctctct gttcggctga taaatctgcg acacccttgc
     1321 accgagagcc tctttttcta tttcactttt aatatgtctt aaaaaaattc cgtcaagcgc
     1381 catagtaact ccgtaaatta tttgtgatat ttaccgttcg atgaaatctc aaacgcacgg
     1441 taaatctgtt cgcttaaaat cattcttgcc atttggtgag gaaaggtcat tctgctcatt
     1501 gaaagacgga catctgcccg ttttttaacc gattcgtcaa gcccgtagct gccgccgata
     1561 ataaaatcaa cggtgctttt tccgcttacg gacgcattgt caatcagcct tgaaagctcc
     1621 tcactcgaca tagactttcc ctcaatacac attgcaacaa cataatccga aggcgaaatt
     1681 ttttgcatga ttcgttttcc ctcagagaaa ataacctcat caatctgcga cctattcggt
     1741 atgttgctct taatgcgttc ttccgaaagc tcaataatat tgaatttaca aaatgcggtc
     1801 aagcgttttg catactctgc aattgcgtcg gtaaaatatt tttccttgat tttgccgata
     1861 caaattatgt taatcttaat catattcctc ttgtttgttt aaggttaaaa gatgatggct
     1921 tttgttgtgc ttacactcgg agcaacatca agcgaataat cgcttttgta cttcattccg
     1981 tttgatgtga gcaggtctac ggatgttgac attgcaagcg gaacggtatt attttcttcg
     2041 ctgagatgac cgagcataag tcttaaagtt cccttttcaa caaggttaac aagttctttt
     2101 gcacaagcct catttgaaag atgtcctctg tttgaaagga ttctctgctt tagcggataa
     2161 ggataaaatc cgtttttgag catattaata tcgtgatttg actcaagcac aacaaagtcg
     2221 ctctgctctg cggcagttct gacatcgggc aacataatgc ccatatcggt tgctataagt
     2281 gcggattttc cgtcgggagc agtaacacgg taacaacagc tttccgccgc atcgtggggg
     2341 gtgtcaattc gctgaacacg catattgccg attacaacct cgtcagttat aacatctgca
     2401 tccgtgtttg gatcaagctt attacctgcc ctcaaagcat tgagcgtacc aaggcttgaa
     2461 tacaccttaa agccgtaacg ctttgcaagc acacgcaacg cactgcaatg gtctgtgtgt
     2521 tcgtgagtta taaaaaccgc cccgacactg cccatatcaa gtccgtttgc aagcatggca
     2581 ttttcaatct gcttacatga acggcctgcg tcaatcagta cgccttcgct tgccgaacct
     2641 atgtagtagc tgttaccctt acttccgctg aacagcggta ctgctcttgc caaaacaatc
     2701 aatccttatc tttagtataa cgaatatgat aacacaaatt ttaaaatttg taaattatct
     2761 cacaaaaaag ccgttctcac aaagaaaacg gctttgattt ctaattaaat tttagtcagg
     2821 caccaagctc ttgctcgttg tctcctgtaa aatacacctt tttgatatct gcaccaagtc
     2881 ctctgaactt ttcaacaaca tcttcgtatc cacgctcaat gaactgaata ttagaaatct
     2941 ctgttgtacc gttaatttca agagcggcaa taatcatagc cgcacctgca cgaaggtcgg
     3001 ttgccttaac gggagccgct gtgagcggaa caccgccctc aatgattgca agtctgccct
     3061 caacagaaat ctgcgcaccc attctgataa gctcgctgac atactgatag cgattatccc
     3121 aaacattctc gttgatgatg cttgttccgg gaacgctcat aagcaatgcg gcaaactgcg
     3181 gctgacagtc tgtcgggaag ccgggatgcg gcattgtctt gatattacag cgctttagcg
     3241 gagcagatga cgcatcaacc ttgagagcct catcatattc cgtaatctta acacccatct
     3301 cacgcagctt tgcgctgatt gattcaagat gcttcggtgt aatattcttt accgtaatac
     3361 aacctcttgt tgcggcggcg gcacacatat atgttcctgc ctcaatctgg tcgggaataa
     3421 tcgaataagt aatgccgtga agatactcaa cgccacggat tttgataaca tccgtacctg
     3481 cgcccctgac atccgcaccc attgaattaa ggaagttcgc aaggtcaaca atatgcggtt
     3541 ctcttgcggc attttcaata atggtctgtc cctttgcctt tgatgcggca agcataatgt
     3601 tcattgttgc accaacggac acaacatcaa ggtacacatg tgtaccgaca aggctgtcgc
     3661 attctgcctc tataatcgca ccgtcaacaa gctgagttgt cgcaccgaga gcctcaaagc
     3721 ctttaagatg ctggtcaatc ggacgcacgc caaagttaca gccgcccgga agagccacct
     3781 tagccttgcc gtacttgccc aaaagtgcgc cgaggagata atatgacgct ctcatacctc
     3841 ttacaaggtc ggtcacagca ttgcatgtgc ggatttttgt aggatcaata tataaggacg
     3901 aacggttgat tcgtcttaca ttagcaccca tctgctgaag aattctgctg ataagtgata
     3961 catcgctgat gttaggaata ttttcaatct ggcacggttc atcacaaaga ataactgccg
     4021 gaataattgc aacggctgca tttttcgcac cgctgattgt cacttcaccc gataatggct
     4081 ttccgccggt aactacgaac ttctccaatt gttacacccc aattaatgtg tagaagatac
     4141 ttttaactaa ataagctaaa tatctgaaaa tgtatatcta tatagtgtat aagtaaaaat
     4201 caaaaattat acgaatctaa aattcataat gagaactaat ttgttacatt ttattaaaaa
     4261 cgaacccact cggttacgca gatgtaattt aacaattctc ttacagaaaa tgatactaca
     4321 aaattgtagt aaagtcaacg gaataataaa actgtaatct atttttgggc aagttgtact
     4381 caaattatta atttgttgct ttttttgttt ttaatataac caaccatgct ttttaaaacc
     4441 gttttttcct aaaaagaagt aattaatcaa agcaattttt tgtaaaataa ttacaaattg
     4501 aaacagttat tatattttcc taattgaaaa tttgcaggca aatctatcgt atatatttat
     4561 tctttgcaaa tcaaacgaat aaaacaaaaa tatctaaagg taaatttttt taaaaatcac
     4621 agacaaaatg attattatgc cgaaaaaaag actttactgc cacttgcatt gaatttaaaa
     4681 cttttatcaa ttatgattga aacagaatca gtcggcaagt gtccttttac aatacaataa
     4741 cgacaaaatt aaggcattgc ggcaaatttt taattaacgg gggattcaga atgagcgaaa
     4801 cagcaaaaga accgaaaaaa ataagtaaaa gaagcagtga agaaaaaatt gaaattattg
     4861 ttgcgatttt tctcggaata accgcactcg ccacagcatg ggcatcgtgg ataggttcac
     4921 ttcacggcgg aaatcaggcg actaactaca caaaaagcaa caacctctca tcagagggca
     4981 actcgatgtg gaatgaggct tctcaaaatc ttatgcagga tatgatcaca tggaatgaca
     5041 tcaatgaggc aaaccttaat taccaatatg cggaatctaa aaacgataaa gcggaaatgg
     5101 aaaaatatca gtaccaaatt gatcagctta tgagtgataa ctgtacagaa gaatttcttg
     5161 aggcaattaa ttgggcaatg gatcaaaagg aaaatgtaac tccgtttatg aaggacggtt
     5221 acaccgaaag ttattttgca gaggcacaag ctacaattga agagtcggac aaacttcttg
     5281 aacaaggtaa gaaagataac gcaaacggtg acgcattcgg tcttgtaagc gtaatttact
     5341 cggttgtact ctttatgctc ggtatcgtag gcacattcaa gaatcttccg aacagaagaa
     5401 ttgtgctcgg tgttgcagtt gcaggtttta ttcttgccac tatatatatg tttacaattc
     5461 cgatgccgac aggattcaat attctcagtt atttcggaat ggcataaaac aaaatattct
     5521 gtactcacag cggtgaaagc aaatgctttt gccgctgttt ttttgtaaaa aatcaaaaaa
     5581 acattacatt ttttcgtgtg tgtctattga ctttttaaaa agggaatgct atattataat
     5641 taacatatga gcatatcttc atatgttcaa gtataactat taacctgaga gaaaattaaa
     5701 ggggacgcct atggaaaaca aagaaaaaac aaccactccc gaaatgcccg acattgatgt
     5761 gctgtttgag cttgcagacc tttttaaggt tttcggtgat tcaacccgac ttcgcattat
     5821 gtacaccatt tcggaaaatg aaatgtcggt gctcaacatt gctgaagctc tcagcatgga
     5881 gcaaagcaca atttcccacc aactgcgtgt gttaaggcag aacaagctgg tgcgtgttcg
     5941 ccgtgaagga aagcagattt attacagcct tgacgatgac catgtgaaac gaatcatcga
     6001 aatgggactt gaccatgtcc ttgaataagg agggagacat atgaggtaca aatatcagct
     6061 tgataatctc aactgcgctc attgtgcagg caagattgag gctaaaattg cagaaacaaa
     6121 cggctttgaa gatgtgagct ttaattttgc gacaaaactt ctcaacttca aaagcgaaaa
     6181 gcagaatcct gtttccgaaa ttcaggcaat ttgcgacagc attgaggacg gtgtaaccgt
     6241 tgttgacaaa actccgaaaa ccaatctcaa aaaatacacc tacactttag acaatctcaa
     6301 ttgtgctcat tgtgcgggca aaattgaggc taaaattaca gaaacagacg gttttgagga
     6361 tgtaagcttt aattttgcga caaaacttct caacttcaaa agcgaaaagc agaatcctat
     6421 ttccgaaatt cagtcgatct gcgacagcat tgaggacggt gtaactgttg ttgacaaaac
     6481 tccgaaaaat gatatcacaa caaaggcaga acccgaaatc acgaaaaaga aaatcaacca
     6541 tgacacaatc ttccttgcaa tttcaattgt acttgctgta gtgtccgaaa ttctccacct
     6601 tacacttgac ggtgttacgg ctattcatta tgttgtactc gcagcgtgtt ttgttgcaac
     6661 acttctttcg ggttacaagg tatttatcaa gggtgcaaaa aacattctaa agctgagaat
     6721 tgacgaaaca acgcttatgt ctgttgcggt aattgcggca ttctgtcttg gagattttgt
     6781 tgaggcggca atggtaacaa tcctcttttc catcggtgaa atttttgagg atcgagcagt
     6841 tgacgcatcc cgccgtgaca ttgaaaagct tgcaaacatt cgtcccgata cagcaacaat
     6901 tattgttgac ggtgcggaac aaattgttcc cgccgaaagc gtagaaatcg gaagtatcat
     6961 tgaagtcaag ccatacgaaa gagttccgct tgacggcatt attattaagg gtaaaacgac
     7021 tctcgacaca tcggctctca caggcgaaag ccttcctgtt gatgcaggcg agggcagtga
     7081 agtactcagc ggcgcaatca acggcagtaa ccttattact gtcaaaacca caaaacattt
     7141 cggcgacagt accgcaacaa gaattcttca gcttgttgaa gatgccgccg ctcaaaaggg
     7201 caacagcgaa aagcttattt caagatttgc ctctgtttac acaccggttg ttgtactcat
     7261 tgcagttgca atcgcagtaa ttcctccgct ttgcggactc ggagcattca gcgaatggct
     7321 ctaccgtgcg cttgtttgtc ttgtagcgtc atgtccgtgt gctattgtta tttccgtacc
     7381 tctctcctac tattcgggta tcggtgcggc atccgaagtc ggtgtactca tcaagggcgg
     7441 aaaatatatt gaggctcttg caaaagcaga cacattcgta ttcgataaaa caggcacact
     7501 cacaagcgga aagctcagcg taaacaaggt taatactgtc ggttcataca gtgctgacga
     7561 agttcttgct cttgccgctg caagcgaaaa atattctgct catccgattg cctccgcaat
     7621 cagagaaagg gcaaacggtc ttgaacttcc cgagctttcc gactacagcg aaagtgccgg
     7681 tcacggaaca agcgcagttt ataacggcaa aactattcag tgcggcggtt caaagattct
     7741 ttcggacgaa cagaagaaga ttgcaaataa agacgattct gttttcgtaa tttatgacgg
     7801 tcagcttatc ggttcgctca atgtcagcga tacagtaaga cctgaggcaa aagaggttat
     7861 ctcacagctt aaagttctcg gtgtcaagaa cacggtaatg ctcacaggcg acagacaaca
     7921 gcctgccgaa aatgttaaaa acgaactcgg actttccgaa tatcacgcag aacttctccc
     7981 tgctcaaaag cttgaacttt tcaagggctt gaaatcaaaa tccaagggtg cttgttttgt
     8041 aggcgacggc atcaatgatg cacctgttct ttcggcaagc gactgcggta ttgcaatggg
     8101 attcggcagt gaagccgcta ttgaagcgtc agacgcagtt ctcgcatcag gcacactcaa
     8161 acagcttcca aaggcaatta aaattgcaag aagtgttatc aacacagtca agggcaacat
     8221 catcttcgcc ctctcaatca aggctcttgt aatcatcctc gccgcattcg gtcttgcaca
     8281 aatctggatg tccgttatcg ccgacacagg cgtcagcgta gtctgcgtac tcatagccgc
     8341 aagactcctc aaaaagaaat attgattttt tgcaaatcat atcatttatt atgataaagc
     8401 accgtgagct ttcacaagtt tcacggtgct ttcatttgcc aaaatttttc taaacataat
     8461 cttatattat agtattttaa aatcattgac ttttataatt atataaatta taatgttttt
     8521 gtcagcgctt gtaactgata aataaacttc ggagagatta atttgaaaaa gatattttta
     8581 ttattagtaa ccgctttatt tttactttca ttatatggat gtaacacttc ttcatcaagc
     8641 aataacccca ctgaacaaac aaccgtaacg aatacagatg atttatctct tgatacagat
     8701 acagatacag attctgaaac agaatttaat tacgatttgg agatttacaa caacgataaa
     8761 aaaatagata ccttaaatct tttcgatgca cttatgccaa ctgaggatgg actcatatat
     8821 tcaaaaatca acgaaacttc tccgaatgaa atagaatact acagatacta tttagacaaa
     8881 aagagcagta taaaactcgg ctcaataaaa gactggacaa tgcaaattaa cgataaagcg
     8941 tatgtaaata atcacttatg ttttatggca agcacgggtg acattacaga tgaagaaaac
     9001 agaacccttg aatttattga tatagacctt aataaaaaca aaatgactac tgtcttttct
     9061 gacaaaggcg gttttcccta tgataccgtt acaggtgcag acaatcttgt cataattaca
     9121 aaagtattaa acaacggtac ttctttggaa ctgtatgaca ccgaaacgca aaagttcaaa
     9181 caactgaaat atttagagtt tgatgataag aactgtgtag gaaaaactat aagaaaagtt
     9241 tcaattgacg acaaaacaaa aacaatctgc ctcttggttt tggactgtgt ttcggaaaca
     9301 gatgtttctt taagaataga aacctatgac tatgatatga attttcttaa aagctacgat
     9361 atctccaata tttcggatga ttctaacgaa ttgattcaag gagtgcagtt ttttgatttc
     9421 agaaacaact accttatcta tcaaaatttt agtatgacaa gatgtatagg ttatataggg
     9481 aacaaaaaat tgcaaaaatc cgatatgatt gacaacattg acgacaccta ctctatggct
     9541 caaactccac aaaaaggata taatacagtt ttatcattta aagatgttga tttagaacgc
     9601 aatatatact tatttaatac cattgacaaa acaatgaaaa aaacaaaatt caaacctgaa
     9661 gaagaaaact actatatcgg ctcaatgtta agaactggaa aagataattt gatgataata
     9721 actactcctg ataatgcaga caaaaaaagt aatcttaatc caaaactata ctttacaaaa
     9781 ctaagcgact taaattttca gtaaacaggc ggtaaaaatc aattaaaatt cattttgcaa
     9841 attatctgtc aaaatcctgc aaaaaattta atttatgggc aatactgctc tttacttttt
     9901 aaggtattta ttgtataatt agcggtaaag taaaagggta tatttaatgt tacaaaacac
     9961 cttttgctca caataaaaag gataggaggg acaaaacata atgatcagcg gtgctgaaat
    10021 tatggtaaaa tgtttggaag ccgagggcgt tgacatagtc tttggttatc ccggtgcggc
    10081 tatttgccca ttttacgata aagtttacga ttcgagcatt acccacattc ttgttcgtca
    10141 ggaacagaac gctgctcatg cggcaagcgg ctatgcaaga tgcagtaatc gtcccggtgt
    10201 ttgcgtggca acttccggtc ccggtgcaac caacctcatc acaggcattg caaccgccta
    10261 tacggactct attccgattg ttgccattac aggtcaggtt cgttccgacc ttctcggcag
    10321 agatgtcttt caggaagctg acatcacggg agcttgtgaa ccgtttgtaa agcacagtta
    10381 tctcgtcagc aaaacagaag accttccgag agttttcaaa gaggctttcc atattgcctc
    10441 aaccggcaga cccggtcctg tacttatcga cattcccgtt gatattcagg aaaatgaaat
    10501 tgaaagtttt gaatatcccg aaagcgtaaa cattatcggt tacaaaccga acactaaggg
    10561 acacgcaatt caggttaaaa aggctgttga ggccatcaac gcaagcaagc gtcctgttat
    10621 cgtatcaggc ggcggcgtac taagttcggg tatcaagctt aaacttcaaa aatttgcaga
    10681 aactacgggt atccccgtta tttcaactat gatgggcatc ggtgttatgc ccagcgagca
    10741 tgagctttat ctcggaatgc tcggcactca cggcaaggct gttgccaacc gtgctcttca
    10801 cgaagccgac cttgtaatcg tatgcggtgc aagactcggt gacagagctg ttgcggctcc
    10861 cgaccagatg agtgaaaaca caaaggtaat tcacattgac attgaccctg ctgaaatcgg
    10921 taagaatgtt aaaacagaaa ttccgattgt aggcgatatg aaaaatgtca tcaatatgct
    10981 gcttgacagc atcggcgatt acaaggttac aacaatgtgg agcgaaaccg taaagaactg
    11041 gaaaaaagac ctttaccgtg agcctcccgt ttttgacggc tttgttgagc cgagaacact
    11101 tgtcggtcat ctcagtgcaa tgttccgctc aaaggcaatt cttgttgccg atgtaggaca
    11161 aaatcaaatc tggtgtgcaa acaacttccg tattcgtgag ggcagattcc tcacaacagg
    11221 cggtatgggt acaatgggtt actcaattcc cgctgcaatc ggtgcaaagt ttgcaagacc
    11281 cgaccgtgat gttattgtaa tctgcggtga cggcagtttt cagatggggc ttaatgagct
    11341 tgcgactatt gcaggcaatc agctcggaat taaaatcatc attatgaaaa acgcacgact
    11401 cggaatggtt cgtgaacttc aggacaaaca ctacggcggc agacactccg caacaattct
    11461 caacggtgat cccgacttct tgaagattgc cgatgcttac ggcattgacc atgcagaggc
    11521 tcattcaaac aaggaagccg aaaacatcat caagggtatt gttgattcgg aaaaaccgtt
    11581 cattcttgtt tgcgatgttc accccgacac tccgtcaatt taatgaggtg ataaaatgca
    11641 gtatacatta tcaatacttg ttgaaaatca ggcgggcgtt ctttcaaaga tttcgggact
    11701 tttctctcgc cgaggtttta acatcgactc actcgcagta ggtgttactc aggacccgtc
    11761 ggtttcccga atcacaatcg ttgcaaacgg tgacgagtac attgttgaac agcttgaaaa
    11821 acagctcaac aagctcattc ccgtcattaa ggtaaaaagg cttaacgagg gcgaatttat
    11881 cagccgtgag cttgttttaa tcaaggttca ctgcgccgcc tcaaaaagag ccgaaattgt
    11941 caaaacggtt gaaattatgc aggcgaaaat cgttgatgta tccccttcgt cagttaccgt
    12001 tgagtactgc gaatgtgcaa gccgcatcaa cacgcttgtt gacttactca agccttatgg
    12061 tatccgtgag attgtaagaa caggtactgt tgccattgac agaggcacag cttcggtttc
    12121 cgtttaatct tacagttagc atatatttta atttatatgc cgcgtttgcg gtaaggagga
    12181 ctttaatatg aaagactaca caaaaaacat gacagcacca atctactatc agtcagattg
    12241 taaccttgac cttctcaagg gtaagaaaat tgctattatc ggttacggca gccagggtca
    12301 tgcacacgct ctcaacctca aggattcagg ttgcgatgta atcatcggtc tttacaaagg
    12361 cagcaagagc tgggcaaagg ctgaggcaca gggctttaag gtatatacat cggcagaggc
    12421 tgcaaagcag gctgacatca tcatgattct tatcaacgat gaaaagcagg cagctcttta
    12481 caagaacgac atcgagccaa acctcgaagc aggcaacatg cttatgttcg ctcacggctt
    12541 taacattcac ttcggttgca tcaatcctcc aaaggatgtt gatgttacaa tggtagctcc
    12601 taagggaccg ggtcacacag ttcgttcaga gtatcaggtt ggtaagggtg taccttgcct
    12661 cgttgctgtt gagcaggatg ctacaggtca ggctaaggat ctcgcacttg catatgcact
    12721 cggtatcggc ggtgcaagag ccggcgttct tgaaacaaca ttcagaacag aaacagaaac
    12781 agacctcttc ggtgaacagg ctgttctttg cggcggtgtt tgcgcactta tgcaggcagg
    12841 ttttgaaaca ctttgcgatg ccggttatga cccaagaaat gcttactttg agtgtatcca
    12901 tgagatgaag ctcatcgttg accttatcta tcagtcaggt tttgcaggca tgagatattc
    12961 aatctctaac acagctgagt acggtgacta catcacaggt ccaaagatca tcacagagga
    13021 tactaagaag gctatgagaa aggttctttc tgacattcag gacggtacat ttgctaagga
    13081 cttcctcctt gacatgagcg atgccggttc acaggttcac ttcaaggcta tgagaaagct
    13141 cgctgccgaa gctcctgccg aagtattcgg taaggaagtt agaaagctct acagctggtc
    13201 tgacgaagat aagctcatca acaactaatg ttttttagtt cgtgaaggca gtttgatata
    13261 ttcaaacttc tgtcacccga gcattacata gtacgaatta acggttcagt caatttgcct
    13321 gaaccgtttt ttgttgtgca ataaaagggt tcagcttttt acggctgaac cctttaccgt
    13381 tataatttat tacttttagg aatcaatatt tatcatatga aaatgcgttg taagaatcgg
    13441 taaggtactg tcttttctga tcggttgtaa actgattcca aagttttgga tagccgtcaa
    13501 cagaacagta aacaaactga ctgtacatat gtgcatttac acaattaccg agtacactca
    13561 catttgtggc attatatgcc tgttttgttg ttcttccggt attattgtaa taatggtatt
    13621 ccaatccccg actttcaaga gccaaatgag cagaagagta tccacgaaca accaaaactg
    13681 tgccgtcata attcaatgta tagttttcgc gttcaagata acggtcaaca tttgaggttg
    13741 acaattcaac ggcattaatt atatatttct tagcagattt gtcatagaaa taagtcagtt
    13801 gattcgggat ataagttcta taatcatcaa atccgactaa cgaaaacttt ccgtccttaa
    13861 aggtatacac ctttgcattc aaatagtatt ccttatctcc tgcttcctgt actataagct
    13921 cgggaacacc gtcaaaatcg agatcggcaa actgcacacc agccaaagca acatttccta
    13981 ccttgagttc aggtaaccat tccgattcat gcttgagcag ataatctatg tatgcatctc
    14041 ttgttttatc tgtagtctta tacttaaatg tcacacctga cggattatag atacttgtaa
    14101 atttcttgcc gtccttagaa acacatctta cggtataagt gtaggtctgt cctgctttta
    14161 catttttatg agtgtaataa ttatttgttg tatcagcaag ctttttccac gaaccttttt
    14221 cttttacata aatacgatac tttgaattat cttcgcaaac atctgtccat gaaactgtaa
    14281 ttccgccatg cattgagtca acacgaacaa tctccggaca ttcattgcct aaattcgcct
    14341 tagaaccttt tgtatcataa ccgctctgaa aaaccttgcc gttacttgaa atgcaacgaa
    14401 cagtataaat atactgaccg tttacggaat tatcttttat gcttagttct cttgatacaa
    14461 gtcccatatc aagatagctg ttacccgttg tatctgcaag tttgttccaa ccctcaccgt
    14521 ctttgtagta cacacgatat ttttcagcac ctgcaacctt attccacgca agcttgatac
    14581 cgtcatatgt atattctgcc tttgatattt tcggtgtggc aacatatttt gcgctcattc
    14641 ccacagggtc ataaccgctc aaatactttt tagcgtcgga actgattgct cttacagtgt
    14701 atgtataggt tttattcggc tgtaaatttt tatgtgtcac aacacctgtt ttgttatcgc
    14761 atacttttgt ccagccctta ccttctgttt tgcagtacaa tctgtaattt gtattgtttt
    14821 cagtctccca aatcacctta ataccgccgt ttacaacatt ggtttcaagt attttaggag
    14881 cttgattata tctgatactt gagccttttg ggttaaatcc actctcaaaa ctctttccgt
    14941 catcacttat acacctcacg gtataagtat aggttcccac atcaacagat ttatcaacta
    15001 tagaattaga agtcgtatct gatactctga accaatctga cgaatttttc tggtaaattc
    15061 tatactttga tgcaccgttt actttgttcc atgtaatttt cacaccgccg tttacatttt
    15121 caagctttga aatttcgggg gcggcaatat attttacact tttgcccttt gaatcataac
    15181 cgcttgtaaa gctctttccg tcagcagaaa tacatcttac agtataggtg taattcctgc
    15241 ccgatgaaac atccttgtcg atatatgatg ttgaagttgt atcgaccatt cgtgtccaac
    15301 ctttacggcc cttgtagtaa actctgtatt tagccgcacc gttcactttg ttccatgtaa
    15361 gctttacacc gccgtaaacg ctttcggctt ttaaaatttt cggtgttgcc aagcttgccc
    15421 ttgcaacctg tgcatactgc acaggtgtgt taagcggttc aaccgcattt gcagaaactg
    15481 ccgaaaccgc aaccgcagac atcgacatta ccgccgccat ggctataggt aaaaactttt
    15541 tcatagttat ccctcacttt gtaaatattc tacgcattat taaaaacttt cgctaaattt
    15601 ttatgcaagt taattgtaac attaaatgat ataaaaagca atacatcttg ataaactatc
    15661 acaaattttt aagctaaaat aaataaaccg ttcacaaaag cgagaacggt ttattttata
    15721 tattctgttg atgttttgaa ttatttaaaa taatttctgc gttttgcaaa aattactgca
    15781 caacctgcaa gcattgcaac aagaagaatt acagcaacgc tgttctgtcc tgtctgtaca
    15841 gcaccgctgt tattctgtga attgttcggt gtgtcatttg ttgctgtgtc gcttgttgaa
    15901 acaggcttag ttgtcgaagt tgcagaagtt gtatcgggta ctgttacagg ttcgtcaact
    15961 gttgcaaccg aagttgtagg ctcagtagga acagttgtat tcggtttatt agattccaaa
    16021 ccaaaattca tttttgacaa ttcttcaaga atactatcat caataactcc gctttcataa
    16081 gcctctttaa ttgagtaaac attgccattc ttataaagca taacatcatc gccatggtta
    16141 taataataag tatagtcgcc aattgtttgt tcaatcataa cgcctaaact cataaagggt
    16201 atatttctaa aacatactgt ttcatcactt gtagaaccaa caatttcgac attcaaatat
    16261 tcaggtgctt tgccattgta atatttattt ataattacac gctttatttc tgaaaggaga
    16321 gctctatctt caccctttgg ggtaacatct atcttacccc aaagatttcc ccaaacatat
    16381 aattcataga gcatatcatc atcaattaca cctgtttcat aggcatctga caaggtatat
    16441 actttattat tcttgtataa caaaacggga caatctctcg gataagaaat agtataattt
    16501 cctaaatcaa atttcacttc atctgtccag tgtgtaaaac tatccataaa atcgaaatac
    16561 acgccaccgt cactggctgt accatatatt cttacttcaa taaaatcagg cttttcatcg
    16621 ccataatatg tatctaacat agcctgttta atatctgaaa tcaagtctga atcagaagtt
    16681 tcatcaggtg tagccgcaaa agctgttgtt acaaccgaaa agcacattac aaatgctatc
    16741 aatgctgtta aaaatttttt catttttatt tcctcatctt ttatttattc tatctgtaat
    16801 aatggtatac gcaacagata ttcaatttaa ttcattatac cgcttaatta tatgtaatgc
    16861 aatatagttg ctaaaaattc acataaaata atcagcaaaa taaaaaccgt tctcaataac
    16921 gagaacggct tttataggga ttatttaatt tgtaaattac tcaaaataat ttctgcgttt
    16981 tgcaaaaatt actgcacaac ctgcaagcat tgcaacaaga agaattacag caacgctgtt
    17041 ctgtcctgtt tgaactgcac cgctgttgtt ctgtgaattg ttcggtgtgt catttgttgc
    17101 tgtgtcgctt gttgaaacag gcttagttgc cgaagttgca gaagttgtat cgggtactgt
    17161 tacaggttcg tcaactgttg caaccgtagt tgtaggctca gtaggaacag ttgtattcgg
    17221 tttattagat tccaaaccaa aattcatttt tgacaattct tcaagaatac tatcgtcaat
    17281 aactccgctt tcataagcct ctttaattga gtaaacattg ccattcttat aaagcataac
    17341 atcatcgtta tggttgtaat gataagtata gtcaccaatt gtttcttcaa ttgaataatc
    17401 aaggctaaag ccttcattgt gcataaaata tactccgccg tcacttgttg aaccaacaat
    17461 ttcaatgttg agatactcag gctctttacc accgtaatat gtatctatca tcacctgtct
    17521 gatttctgat gcaacatccg attctgatat ttcatcaggt gtagccgcaa aagctgttgt
    17581 tacaaccgaa aagcacatta caaatgctat caatgcagtt aaaagttttt tcatttttat
    17641 ttcctcatct tttatttatt ctatctgtaa taatggtata cgcaacagat attcaatcaa
    17701 cttcattata ccgctaaaat atatgtaatg caatatagtt gctaaaaatt tagcaaaaat
    17761 aattctgctc aaatgaaaat gccactttca tagcgaaagt ggcataaatg ttaattttag
    17821 ttgtcaaatc aaacagggtg aaccatattt ttcttgtcaa gcttgtcgcc gttgatgcca
    17881 accttggcat ttcttctctt ttcaaagaag tcgagagcaa ccttcgggaa ctgtgcataa
    17941 gaaagaacat cctcaggctg ttcaatccac tgctcaatct cgccacggag cttatcaagc
    18001 tcaggctcaa gctgatctgc aggacggcct ttgataatct tcttgtcacc gataatcttc
    18061 ttctgaaact cacgatcaat cggcattgga gttgtaccgt actcaccggc aacaagtccc
    18121 ttgaactcgt ttgtgcacat tgagtagcgc ttgcctgtga ttacattgaa tacagcctgt
    18181 gtgccgacaa tctgtgatgt cggagtaaca agcggaggat aacctgaatc cttacgaaca
    18241 cggggtactt ctgcaagaac ttcgtcaagc ttgtcttcct taccggcctg cttgagctgt
    18301 gaaagaaggt tggaaagcat accgccggga acctgataga taagagcgtt agcatctgtt
    18361 gcgagcatct taggatcaag aagtcctgac ttgatgtact tctcacgaag agtcatgaag
    18421 taagcacgga tgtcagagaa ctgtttaagg tcaagacctg tgtcgaactc tgtgcctgaa
    18481 agagcggcaa ccattgactc tgtaggtgcg tgtgatgtac cgagagcgag tgggctgatt
    18541 gctgtgtcaa tgccgtcggc acctgcctca acacccttta aaagacacat tgatgcaaga
    18601 cctgatgtgt agtgggtgtg gagctgaagc ggaagctccg gaacagcggc tttgatagcc
    18661 tttacaaggc tttcggttct tgtcggagta agaagagcag ccatatcctt gatacagatt
    18721 gaatctgcac ctgcatctgc aattctctta gcatactcaa catagtattc atctgtgaat
    18781 acaggacctg ttgtgtagct gatagcaacc tgtgcatgac cgccttcttt gttagcggcc
    18841 ttgatagctg ttttaagatt cttgatgtcg ttaagagcat caaaaatacg gataatgtca
    18901 ataccgtttg cgattgaacg ctgaacaagg tactcaacgc agtcatcggc atagtgacga
    18961 taaccgagca tattctgtcc tctgaaaagc atctggagct ttgtgttagg gcaatgctct
    19021 ctgattgtgc ggagtctgtc ccacggatct tcgtttaaga atctgaggca tgagtcatat
    19081 gttgcaccgc cccagcattc gagtgagtaa taaccgattt tatcgagttt gtcaagaaca
    19141 gggagcattt cctctgttgt cattcttgtt gcaatgagtg actgatgagc gtcacgcaga
    19201 gcagtttcgg taactctgat tttttttgcc attttacagc atccctttct ccgaattatt
    19261 gattagttaa gtgttacgag aaccttacct gagtcaacag actcaccctt tgcaacatca
    19321 actgttgcaa ctgtgccatc ctgcggagcc ttaacgggag tttccatctt catagcctcg
    19381 atgaatacga ggtcatctcc ggccttaaca gcctgtcctg ccgaaacaac aacattaaca
    19441 actgtaccgg gcataggagc ctttacaaca acagaaccct gagcgcctgc gggagctgcc
    19501 ggctttgctg caggagcggg agcggctgcc ggagcaggag cggctgctgc gggagctgaa
    19561 gagccaccga gttcttcaac ctgaacatca tatgctgtgc cgttaactgt aattcttaaa
    19621 ttcttcattt ttagtatccc cttttatttt aacaagtaat catttatcag atagttgaat
    19681 gcttctttga aagtgttgaa acacgcttac ccgagagcat atcaagagca gaaataagag
    19741 tctgacggag ctgagcttct tcaacaatac cgtcaacata gccgttctga gcggcattgt
    19801 aagcagaaag attctcgtca gcaaacttct gagcaacctc agcctgctta tctgtggcaa
    19861 cattcataac ttcgggagcc ataatgaatg cggcagcctc aacattaaca ggcgaaataa
    19921 ccgcatcggg aagtgcgtaa acaacatctg cattagcgcc tgtgcctgca agagcaacat
    19981 agcctgaacc gattgccttg cctgtaacaa cagaaatctt aactgttgtt gcctcagcat
    20041 aagcggctga cgcctttgtt gccgacttga ttgactcaaa gcccgggcag tttacgaatg
    20101 ttacaacagg gagtgagaaa gcgtcgcaga aacgaacaaa ctttgctacc ttgtttgcag
    20161 acttgcaacc aagctccttg ccctttgtaa caacaatacc tacaacctga ccgccgagtc
    20221 ttgcaaaacg aacatttgct tccttgccgt aatcattgaa gagctttaca atgctgttgc
    20281 cgtcaacagt tctgctgact acacaaccgc aaccgtcctc tgccggagct tcttcaaatg
    20341 actgaggagc cattgtgagg ttatttgacg gaagataaag gataagttcc tttgcagcct
    20401 tgattgcctt gtctgcgtcg tcacaaacga ttgaggcaat accgttttca gcattgtaag
    20461 cggcatcgga atgcttgcct gttaccgaaa gtgaaagctg tgcgtctttg ctcatgataa
    20521 cgatgtctgc gcttgcggcg ttaagagcgt ttgttccgag gcaagtgccg agaacaaccg
    20581 aaatctgcgg tacaacaccg gaaagtgacg cagccgcatt gagaacatca ccgcaacctg
    20641 cgagaagctc tgtaccctga ttaagtctgc cgccaacgct gtcatagaaa cctacaacag
    20701 gagcgcctgt cttgagtgca agaccataca gctttttaag cttggcagcc tgcgccttac
    20761 tcatagcacc gccgcaaatg tcgctgttct gtgcaaacgc ataaacaggc ataccttcta
    20821 ctgttccaaa gcctgcaaca acctcggcaa aaccttcacc ggattttgca aaggcatcaa
    20881 tttcacaaaa gctgtctgca tcaaaaaacg ccgtaattgt cttataagcg gaagttgcgg
    20941 caatttcagc ctttgcctga ttgatctttt caatactcat cttaaaatcc tccaatacca
    21001 tgtattgaat atgcacgaaa actgagcgtg catactaatt ttctacacat acattatact
    21061 ctataatctt caaaagtaca agaaaaacac gctgtactat ttcaattttg aacacattta
    21121 atagttattc cgtgaaaacc tttaatttat tgtcgaatta acaaatagtt tgattgaccg
    21181 tttcggaagt atttttcaaa aacggaaaat taaagctgtt tgccgtttaa aaacgggttt
    21241 gcaagcagtt ttttaacctc ttgttcggtc aaatctctcc agtcgccctg tttgagcata
    21301 cccattttta ctccgccgat ctgggtgcgt ttgagtcttg caacctcaag cccgacagcc
    21361 tcgcacattc ttctgatttc acggttttta ccctcgtgaa gaatcatttc aagaactact
    21421 ctgccctgct ccttgtgaat tacatggaca tatgcaggag cggtttttct gccgtcaagc
    21481 tcaacgcctg tttcaagctt tacaagctga tcctcgtcaa ttgacggtcg aacggttact
    21541 ctgtaaatct tgtaaacatt gtttttcggg tgcataacct tgtttgcaaa gtcaccgtca
    21601 tttgtaaaaa caagcatacc ctcgctgtct ttgtcaagtc tgccgatcgg ataaactcgc
    21661 tcgccgacat tctcaacaag ctgtgcaaca cactttctgc cacgctcatc attcattgtg
    21721 gtaatgaatc cacggggctt gttgagcata atatatcggt aattaccgcc cttcggcaca
    21781 acaatcctct tgcctcttac aaacaccttg tctgtaggaa gaaccttatc gccgagaatt
    21841 gcggttttgc cgttcacctt gacatgacca ccgagaataa gctcctcggc ctttcgcctt
    21901 gacgcaatac cgcattgcgc tatgaatttc tgaagtctta taggttcaat tttagccata
    21961 tgtaaattcc tttttattaa aattttctgt atatttaagc tgtcacgaaa acagatttcc
    22021 tattgccgaa aatattgaca cactcttttt atccgattta atcttttcgc ctgcaacaat
    22081 gttgcattta taaagcagct ttccgccgag tgtgtattca attctgccga ccgattcgtt
    22141 cttttcaatc ggagcataca aaaagctgtc tatgaagatt tttttcttga ttttatcgca
    22201 atcctcacgc tttaaaacga ttgtgttgtt cttctcccct gtaaccgtta cgctgtcctt
    22261 atcaccgccc acgcacggaa tatcggcaca aaagtcagcg tccttgcagt caactcccct
    22321 gtacttttca aaagcgtaat cataaagaga aatatggtca ttccaatcgt tgcggtcatt
    22381 cagagtgacg cacacaagcg ttacaccgtc tttttttgca gaggaaacaa ggcaccgccc
    22441 tgccgccgtc gtatagcctg tttttccgcc tgtacagtag ggataaagcg acaaaagcct
    22501 gttatgattt gcatatgcgg ttttctttga tttcggttca agaaattcaa cggtcacgct
    22561 cttcttagcc gtaagatttg caaaatcgtc attttcaagt gcatatgaca taagcagagc
    22621 catatccttt gcacttgagt aatggttatc atcgtcaagt ccgctcggcg ttacaaaatt
    22681 ggtattcgtc ataccgattt gctttgcctt ttcattcatt cgttgtgaaa atttttcggg
    22741 actgcccgaa attgtatatg ccgccgcatt cgccgcatca ttacccgacg ccatcatcat
    22801 tcctgacgca aggtccgaaa gtcggacttt ttcaccgact ttaagataca tcgaactgcc
    22861 ctcggcaacc atttcctgtt tgaaggttac ttcgctgtta caggatgccg cctcctcaag
    22921 cgttatgaga gatgtcataa tctttgtggt gctcgcaggc ttcattcttt catctgcatt
    22981 ttttgagcag ataaccgtgt tgttatcggg acaataaaga acaaatgcct gtgcagaagt
    23041 tgtgggagga gtatcctccg cagtctttgc gcccataagc acaaacggca taacaaagca
    23101 caccgcaagc gagattattt ttttcataag gacaccccct gcataaatct atgccgaggg
    23161 gtgttgcaat attacgaatc agccgtctat atcgtcctgt gtgatttcgg aaaaatcgtc
    23221 tgcggatt
//
