LOCUS       c00028_NZ_BPQU..       19657 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_BPQU01000028.1 Methylobacterium mesophilicum strain NBRC 15688
            entry28, whole genome shotgun sequence.
ACCESSION   NZ_BPQU01000028
VERSION     NZ_BPQU01000028
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:40:05
            Original ID  :: NZ_BPQU01000028.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 19657
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..19657
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1439:9657]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1440..9657
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..19657
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..19657
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(66..710)
                     /locus_tag="ctg28_1"
                     /transl_table=11
                     /translation="MTTRTLYYAPGACSLAAHIILEESGLSFEGVKLNLAAGDQRAPEY
                     LAINERGRVPALVEDGWVLTECAAILRHVARTVPEKGFWPTDLREQARADEWLGWLAAN
                     HHVAYAHVRRPERYTADEDAFPGIRDKAADTYGDLCTMTEVHLSNGGWAVGDRYGVVDA
                     YLMVFWVWASGASLKFDMAERFPAWHAHARRVAERPAVRAVFAREGLTLPA"
     CDS             complement(720..1112)
                     /locus_tag="ctg28_2"
                     /transl_table=11
                     /translation="MTPTIRTDWQPHPGELLLIDLEPVRGTEQNGIRPALVVSDPDMNQ
                     LTRRVIICPITRNPHPWPTKVFLPAGLVVEGAVLVDQVRSIDRATRILRSLGSAPDDVV
                     AEVRGKLRSLLGLTFDGADAPSVQQR"
     CDS             complement(1090..1386)
                     /locus_tag="ctg28_3"
                     /transl_table=11
                     /translation="MEAKVIRWGDDLAVRLSSAEAEELGIREGETVEIISKGRPKVEPK
                     QWTGRRYVDGLPVYTLAEMISEARRLGPEAEPETIDWGPDRGSEIIDDANDPY"
     CDS             complement(1440..1982)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_4"
                     /sec_met_domain="ALS_ss_C (E-value: 1.6e-24, bitscore:
                     78.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAMNTHYPDAGRVEPVNRHTLAVIVDNEPGVLARISGMFSGRGY
                     NIESLTVSETEEARHISRITIVTTGTNAVIEQIKAQLDRLVPVHRVVDLTLQGNALERE
                     ICLVKVKGEGEHRSEALRLAAAFGAKTLDATLNSFVFELTGATEEIDRFVRLMSVIGLV
                     EICRTGISAMGRGSEPL"
     CDS             complement(2083..3858)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-52, bitscore:
                     169.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGEVMTGAEMVIRAFRDQGVDTLFGYPGGAVLPIYDALFHQDAV
                     KHVLVRHEQGAVHAAEGYARSSGKVGCVLVTSGPGATNIVTGLTDALLDSIPLVCITGQ
                     VPTHLIGTDAFQECDTVGITRHCTKHNYLVKSIEDLPRILHEAFYVAANGRPGPVVVDL
                     PKDIQFASGLYERPEIASHKTYRPAVKGDGDRIRAAVELMATARRPVFYTGGGVINSGP
                     EASRLLRELVAETGFPVTSTLMGLGAYPGTDSKFLGMLGMHGTYEANLAMHECDVMICV
                     GARFDDRITGRLDAFSPFSKKIHIDVDASSINKVVKVDVGIVGDCASVLADMLEAWRAL
                     PSRPEKSNLDPWFQKIGAWKARDCLAYWPSGTIIKPQYAVQRLYEACKDRETYITTEVG
                     QHQMWAAQYFKYDEPNRWMTSGGLGTMGYGLPAAIGTQLAHPKGLVIDIAGEASILMNM
                     QELSTAVQYRLPVKVFILNNEYMGMVRQWQELLHGSRYSQSYSESLPDFVKLAEAYGAK
                     GMRCEKPGDLDGAIAEMLAYDGPVLFDCIVDKTENCFPMIPSGKAHNEMLLSDYLGETG
                     VELGDVISEEGKMLV"
     CDS             complement(4281..5726)
                     /locus_tag="ctg28_6"
                     /transl_table=11
                     /translation="MQDERQDGITALGAVDLAAAIRGRVVSCVEVMRAYLERIHRLNPQ
                     VNAIVGLQDDAALLREAEARDAALVRGEAVGPLHGFPLAVKDLDAVRGLPFTQGSPIFA
                     DRIAEVDTIMVARLRAAGAIFIGKTNIPEFGLGSHSFNPVYGVTGNAYDPEKSAGGSSG
                     GAAVAVVLKLLPVADGSDFGGSLRNPPAFNNCYGLRPSWGRIPVETKDVFSPGLSVLGA
                     IGRSPADIGLMLSVQAGYDPRCPNTIRQDPSAFASPLARDFRGTRIAWLGNFDGQIPFD
                     PGVLELGRAALATFAEIGCVVEEAAPRFDMEQLWRDFLTLRALSVSAALRPLYDEPGHR
                     AQMKPEAIWEAERGLALTADQVVAALEGRTRWYETVRRFMDNYDYLVMPSAQVFPFDKG
                     LRWPREVGGHAMDTYHRWMQIVVPVTMSGLPALDVPAGFGDAGLPTGIQIVARNHGELA
                     CLQLGAAYDAASNWVRRRPPPLH"
     CDS             complement(6054..7136)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg28_7"
                     /sec_met_domain="Amidohydro_1 (E-value: 3e-22, bitscore:
                     71.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVADLFPAAQPPASIAADRITIRRPDDWHIHLRDGAMLKAVLPY
                     TAAQFARGIIMPNLVPPVTTVAAARAYRERILAALPAGLDFTPLMTCYLRDDTDPDEIE
                     RGFAENVWIAAKLYPAGATTNSHAGVTDLIGLAPVLERMERIGMPLLIHGEATDPEIDI
                     FDREAAFMEGSLIPLLARHQGLKVTVEHATTAEILDVVRANRSRVAATITPHHLVINRT
                     HIFQGGLRPHLYCLPVAKRERHRLALRAAATSGEACFFLGTDTAPHVRGAKEASCGCAG
                     VFCGPSALQTYVQVFDEEGALDRFEAFASLNGARFHGLEPNAATVTLERRESRVIEAVA
                     VEDTAVVVFRGDETLPWAVV"
     CDS             complement(7150..7851)
                     /locus_tag="ctg28_8"
                     /transl_table=11
                     /translation="MTTSFLPIDRTIIAREAAKMFLEIQAVHFYKDEPFKFTSGWASPV
                     YIDCRKIISFPRLRATLMDFATATIVREIGYESLTHVAGGETAGIPFAAWIADRLMLPM
                     QYVRKKPKGFGRNAQIEGEVVEGARTLLVEDLATDGRSKVNFCQALRDAGAQVDHCFVL
                     FYYDIFPGSAALMQETGIKLHYLTTWWDVLAVAKEMGTFDPKTLTEVESFLNAPAEWSS
                     AHGGISSFGQG"
     CDS             complement(7985..8437)
                     /locus_tag="ctg28_9"
                     /transl_table=11
                     /translation="MIDTILVLNGPNLNLLGKRQPEIYGRETLADVEALCRETAAGFGL
                     GIDFRQSNAEHVLIDAIHAFRVGSAGIVINAGAYTHTSVAILDALNTCEVPVIECHISN
                     VHRREAFRHHSYISLAATAVLAGFGTHGYALAIRHLAQLRAKAGAA"
     CDS             8815..9657
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: BKACE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_10"
                     /sec_met_domain="BKACE (E-value: 1.8e-88, bitscore: 288.4,
                     seeds: 244, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGSRSATPVVIAVAITGSVPRKKDNPAVPVTVAEQIESTQQAFE
                     AGATLAHIHVRNDDESPSSDPDKFAAVQEGLRTHCPGMIVQFSTGGRGRDPAARGLSLK
                     HRPDMASLSTGSVNFPTIVYENGAGLVTDLASQMKQHGVRPEIEIFDLSHLHGAKRLVE
                     AGLIDARPHVQFVMGVQNAMPAEEHLLDILLAETRRILPDATWTAAGIGRNQAVVMEWA
                     LARGADAVRTGLEDNIRVTKDRLAASNAELVGLAAAAVRSHGRNVASPAEARAALGLG"
     CDS             complement(9742..10479)
                     /locus_tag="ctg28_11"
                     /transl_table=11
                     /translation="MSHVQAHYDNLLADHYSWMNGSSFAEKVSEQRNLLWDLGIYSRTN
                     GRAIDLGCGPGYQSFALSDLGFESVIAIDNCRALLDELNALRAGTPIEPRLADMRSFAT
                     LVERESVDAIVCMGDTLTHLDDRGDVSKLFRDAHDVLRVTGRLVLTFRDLSLELTGLDR
                     FIPVRADDQRLMVCALDYEPESVVVTDIIHIRDNDGWTLRKSSYRKLRLQPAAVAKELQ
                     AIGFLVDQDRSVGRLHAIVARKP"
     misc_feature    complement(9997..9999)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             complement(10801..11760)
                     /locus_tag="ctg28_12"
                     /transl_table=11
                     /translation="MDAAMSAAVQAATRGAAAGIVPETREDSDSLPFRGRTAIRIVPDL
                     GIASVFEPSRSWRDEGPGERLLLVRPAIGRLEVTQGGCKVACCSRDALLVATSRGALFD
                     ALGVDRIDLLAIDRERLTGPLAALETGHIRRIGRDHPGLQTLTVYGASLLRGLIPVGAP
                     GIADLVREHLAQLLAFIVREPGPAISAPGPSRRDLRIQALKAEVEQRLGRPDLSLEAVA
                     QAQQISSRQVQAMFQAEGETFSGFVLARRLDRAMQRLTDAEDARPVSEIAFDVGFGDLS
                     YFNRTFRKRFGLTPSQVRRSGATIDRERFRERDFAMDR"
     CDS             11995..14301
                     /locus_tag="ctg28_13"
                     /transl_table=11
                     /translation="MSRVLYTQNPARQFWKASQRGRAGVGLTSMRTIRLVAILGAGTAL
                     AGPARAETAAPVVALDEISVTATRAPRRIEDVPQSVQVVDRDQIRQQLALTSSPSAVLS
                     KLVPGFSVPNGTISSASESFRGRNLLVLIDGVPVNTPLRDVSRILNLIDLNSVERIEVV
                     AGASSLYSAGATGGTVNFITRRPTDGAPVVTVNTAIRTFTADPVHGVAPETSISVTGKV
                     PDGVDYAFTGSGRFATRTFDGKGRELPSDGQLGQGGADRFQLGNINLRLGYDLDLTKRV
                     EFGLTQILLNQDPRYLTDYSGSFARPDYARSYIGLPVAEDTRSLYLRYTDRDTPLGSFS
                     ILGFYNDINKRFNYSQFAYPANPFVTYSFIPTAPTSLANQTALATERGGINLTLDTDLS
                     VLLPGLKLTWGSDIISESTRQRARDGTDVFTPLQQNSYAGFALLQLPIGERLTVRAGMR
                     YEHFDLDVAGFTRPTTFAASAARNALGYSTFVLPALNVTGGKFSYSAPTFNAGATFNLL
                     PGIDLYGGFSQGYALADIGAFTRRAGLSLAYACPISRPFCLPAGTTIAYSSIAPQAQIV
                     NSYDFGVRGRSGIFSGSLGGFVSTSDDGTTFDPLTNKLSQQKEMIYGVEFTGNAQVTEQ
                     LNLGTVLGYREGRYDTNKDGRLDSYLPNNRIGAPFHGTLSGTYLFANGVSLRVEGEGFS
                     GRDARIDLIGTRFRLKDAFTVNAAFGAPLAGGELYASVDNLFDRAYWNPTATSVRNLTV
                     FGLGRTVTVGYRRTF"
     CDS             14305..14667
                     /locus_tag="ctg28_14"
                     /transl_table=11
                     /translation="MVALEEADDLMVLRYLGPTEPGDETAYLDALEQVGARTEPFALIL
                     VLGGVGKLSAASEKAQALWFKRTRADLERHCRGLVIVRPGFEEAGADVFRRLWNFPIEI
                     APDEPAARASARAYLS"
     CDS             14664..15917
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 53.1; E-value: 8e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg28_15"
                     /sec_met_domain="MFS_1 (E-value: 8.3e-17, bitscore: 53.1,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAASSAPAAVAVTADGRRERYSLFVVLAALYMAQAIPSYLIAAA
                     LPPIMREAGVSRAGIGYLSLLFLPLVLKFLWAPLIDRVRPFARAHRAGWVVMTQVGVIG
                     CILAMLPLGPTNVPGIIGVGFLAALLIATQDIATDGYAVKRLRPEDRAIGNAIQGGSVA
                     LGVVVGGTLSLVLYHHVGWTGMLLSAAAFSVPPLLAAFAMREEAPETGATAPRPSIRAF
                     LRRPEVHTILWVALTYRVSEGLVKAMEGAYLVDAGVPLDRIGYLSGVSAMTAGLAGSGV
                     AALLVRRYGTAATLGLLGGLRTLCFALFTAHAFGAVVGLWPLFGAAGFQTLIRYMEIVA
                     LYSLFMAVSSAEQPGTDFTILACAQLVVYLVGSLISGKLADLLGYGALFGLATFLSGLA
                     TMATVRLLGTGRTGQATG"
     CDS             complement(15902..17098)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 58.6; E-value: 1.7e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg28_16"
                     /sec_met_domain="MFS_1 (E-value: 1.7e-18, bitscore: 58.6,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRIDVRTPGSGVAGRLSLAAASVGFGQSAVLALVPVVAERTGLD
                     AVAMGGVAFAGAVAFLVCAPAWGNWGTGLRLRRLFAALAALMALGHGLFALALTVPALP
                     VAGALVLLVASRIAYGAGAAGVMPHAQAAVLGSVAETARPAALGRLGAGLSAGRILGSL
                     AMGVGVFGTAAPLAVLAASPLLLLAAPDLPGGSPGARAAGADRGGVLRAAAPLMGIGFA
                     LTLGLGQIQIVLGLFLQKRFNLDAPGAAGLAGATFALVAVTMILTQLVLVPRLGPNLRR
                     NLSLGLAGFAAGAGVTACAPAAWVAVLGTVVVGAGIALATPHYTAALVARMPGHAQAAA
                     AGWLASVHVLGQGIGALCGGAAFRIAPALPFWTCATLGLALIVAAVRLRPDDPRHPVA"
     CDS             17251..19065
                     /locus_tag="ctg28_17"
                     /transl_table=11
                     /translation="MVEADISCADVASQVSVRSFLNSLMREWAGWTLATAEAREDDPTR
                     PVLRISLPSRASVIEIAVTHVSSVGQHMFRLPFRELRPGEPPRIMALAAFAAAVANEPA
                     IVGPAAPQAAPIFLRRLFQSLATVEDILVRAPAPGIFLSRDPSFREAERALRFGHSVHP
                     TPRSRDEFTLADSRAFAPEYGRGFPLRWWSAAPETVVQGSSRATSAADLCADLAAEDAG
                     FDPTIFAASGGRVLLPVHPWQAARLALDPEIDALFRTGRLRDHGHAGGPWYATTSLRTL
                     YAPGARFMLKHSLSLRLTNSLRLIKSVECARGLVVDGVLNGPVGAEIAARWPSFHVLGE
                     PAYLALRGADGAALPQTFVALRDNPFHGADERPAAVLAALCEIYPDGRGSGLADTILRI
                     AGRKDADGDGPVEAVALRWFERFLTVTVGPILEIQCALGLLFGAHQQNLVLELTDGWPV
                     RTFFRDCQGTGFVREFLPALREAAPGLDLEAGHLLTSGEAARVMAYYLVVNSVFAVIGA
                     IGIAGLAPEGALIGALRRFVEALAGKDLRDKTCLRLLLDAPALGSKGNFQICFRNLNEN
                     TDVTDPLASYVDLPNPLAAPSARAGARP"
ORIGIN
        1 cctcagagcc atcgtcactc agaccgcctg atccccttca agcgatcgcc ctgcgccgct
       61 cgggttcagg ccggcagggt cagcccttcg cgggcgaaga cggcccgcac cgccggtcgc
      121 tcggcgaccc ggcgggcatg ggcgtgccag gccgggaagc gctcggccat atcgaacttg
      181 agcgacgcgc cggacgccca gacccagaag accattaggt aggcatcgac gacgccgtac
      241 cgatccccca ccgcccagcc gccgttcgag aggtggacct cggtcatggt gcagaggtcg
      301 ccgtaggtgt cggcggcctt gtcgcggatg cctggaaagg cgtcctcgtc ggcggtatag
      361 cgctccggcc ggcggacatg cgcgtaggcg acgtggtggt tggcggcgag ccagccgagc
      421 cactcgtcgg cccgggcctg ctcgcgcagg tcggtgggcc aaaagccctt ctcgggcacg
      481 gtgcgggcga cgtggcgcag gatcgccgcg cattcggtca gcacccagcc gtcctcgacc
      541 agggccggca cccggccgcg ctcgttgatc gcgaggtatt ccggcgcgcg ttggtccccc
      601 gccgcgaggt tgagcttgac gccctcgaac gacagcccgg attcctccag gatgatgtgg
      661 gcggccagcg agcaggcgcc gggggcgtag tagagggtgc gggtggtcat tcggagttct
      721 taccgttgct gcactgaggg ggcgtccgca ccgtcgaaag tcaggccgag aagactacgc
      781 aacttgccgc gcacttcggc gacaacatcg tccggtgccg acccgaggct tctgaggatc
      841 cgggtcgccc ggtcgatcga acggacttga tcgaccaaca cggcgccttc gacgaccaga
      901 ccagctggca ggaagacttt ggttggccat ggatgcgggt tacgcgtgat cgggcatatg
      961 atcacccggc gcgtcagctg gttcatgtcc gggtccgata cgacgagcgc cggccggata
     1021 ccgttctgct cggtgccgcg gaccggttcg agatcgatca gaagcaattc gccaggatgc
     1081 ggctgccaat cagtacggat cgttggcgtc atcgatgatc tcggaaccgc gatcgggccc
     1141 ccaatcgata gtttcaggct ccgcctccgg ccccagacgc cgcgcctcag aaatcatctc
     1201 ggccaacgta taaacgggca acccgtcaac gtaccgacgc ccggtccatt gcttgggctc
     1261 gaccttcggc cgccccttcg agatgatctc gacggtctca ccctcgcgga tgccgagttc
     1321 ctcggcttcc gcgctgctca gccgaacggc gagatcatcg ccccagcgaa tcaccttggc
     1381 ttccatcgca ccgcctcccg cgaggacgcc ggagcatagc agatccgggc cgccgcttcc
     1441 tacagcggct ccgaaccccg ccccatggcg ctgatgccgg tgcggcagat ctccaccagc
     1501 ccgatgacgc tcatcagacg cacgaaccgg tcgatctcct cggtggcgcc ggtcagctcg
     1561 aacacgaagg agttgagcgt ggcgtcgagc gtcttggcgc cgaaggcggc ggccaggcgc
     1621 agggcctcgc tgcggtgctc gccctcgccc ttgaccttca ccaggcagat ctcgcgctcc
     1681 agagcattgc cctggagcgt caggtccacg acccgatgga ccggcaccag ccgatcgagc
     1741 tgcgccttga tctgctcgat tactgcgttc gtgccggtgg tcacgatggt gatgcgcgag
     1801 atatggcgcg cctcctcggt ctcggagacg gtcaggctct cgatgttgta gccgcggccg
     1861 gagaacatgc cggagatgcg ggcgagcacg ccgggctcgt tgtcgacgat cacggcgagc
     1921 gtgtgccggt tcacaggctc gacgcggccg gcatcggggt agtgggtgtt catcgcgttc
     1981 atcgccggct tcgtcctcgt ccagtcctgc ttttggcggc gatccgagcg cgccgccgcc
     2041 catgcggcgg gcagcggccc cgaagggccg ccgccaagca acctacacca gcatcttgcc
     2101 ttcctcggag atcacgtcgc cgagttcgac gccggtctcg ccgaggtaat cggacaggag
     2161 catctcgtta tgcgccttgc ccgaggggat catcgggaag cagttctcgg tcttgtcgac
     2221 gatgcagtcg aacagcaccg gcccgtcata ggccagcatc tccgcgatcg cgccgtcgag
     2281 gtcgcccggc ttctcgcagc gcatgccctt ggcgccgtag gcctccgcca gcttaacgaa
     2341 gtccggcagg ctctcggaat agctctgcga gtagcgcgag ccgtgcagca gctcctgcca
     2401 ctgccggacc atgcccatgt actcgttgtt caggatgaac accttgaccg gcagccggta
     2461 ctgaaccgcg gtcgagagct cctgcatgtt catcaggatc gaggcctcgc cggcgatgtc
     2521 gatcaccagc cccttcgggt gggcgagctg cgtaccgatc gccgccggca agccgtagcc
     2581 catcgtgccg aggccacccg acgtcatcca acggttcggc tcgtcgtact tgaagtactg
     2641 cgccgcccac atctgatgct ggccgacctc cgtggtgatg taggtctcgc ggtccttgca
     2701 ggcctcgtag aggcgctgca cagcatattg cggcttgatg atcgtccccg acggccagta
     2761 ggcgaggcag tcgcgcgcct tccaggcgcc gatcttctgg aaccatgggt cgaggttgga
     2821 tttctccggc cgcgacggca gggcacgcca agcttccagc atgtcggcca gaaccgaggc
     2881 gcagtcgccc acgatcccga catcgacctt caccaccttg ttgatcgagg aggcgtcgac
     2941 gtcgatgtgg atcttcttgg agaacggcga gaacgcatcg agccggccgg tgatccggtc
     3001 gtcgaaccgg gcgccgacgc agatcatcac atcgcattcg tgcatcgcca ggttggcctc
     3061 gtaggtcccg tgcatgccga gcatgcccag gaacttcgaa tccgtgcccg gataggcgcc
     3121 gagccccatc agggtcgaag tgaccgggaa gccggtctcg gcgaccaact cgcgcagcag
     3181 ccgcgaggct tcggggccgg agttgatgac gccgccgccg gtgtagaaga ccgggcggcg
     3241 cgcggttgcc atcagctcga ccgccgcgcg gatcctgtcg ccgtcgccct tgaccgccgg
     3301 acggtaggtc ttgtggctcg cgatctccgg gcgctcgtag aggccggagg cgaactggat
     3361 gtccttgggc aggtcgacca cgaccgggcc gggccggccg ttcgcggcga cgtagaacgc
     3421 ctcgtgcagg atccgcggca agtcctcgat cgatttgacc aggtaattgt gcttcgtgca
     3481 gtggcgcgtg atgccgaccg tgtcgcattc ctggaaggcg tcggtaccga tcagatgcgt
     3541 cggaacctgc ccggtgatgc agacgagcgg gatcgaatcg agcaaggcgt cggtgaggcc
     3601 ggtgacgatg ttggtggcgc cgggccccga cgtgaccagc acgcagccga ccttgccgga
     3661 cgagcgcgca tagccctcgg ccgcgtggac cgcgccctgc tcgtgccgga ccagcacgtg
     3721 cttcaccgcg tcctggtgga acagagcgtc gtagatcgga agtacggcac cgcccggata
     3781 gccgaacagc gtgtccacgc cctgatcccg gaatgcccgg atgaccatct cggccccggt
     3841 catgacctcg ccgcccatgc tctcctcctc cgctccccgg atcgtcggcg gcgttcgtgc
     3901 gccgccggac ggaccggttc ctgtcgtcct gcaccttcgt cacgcgaggc ggcatccgcc
     3961 tcgctcgaag gtcctgtggt cgtcgttatc tcgaacgcgt ggatctcgtt ggtcgtggtg
     4021 tgtcaccggg cagcgggcaa taaaaaaggg ccccgaggga ccctgcatgc gccaccgctc
     4081 ggattgcggc cctggtttag ggccgccccg tcggtgacgc ttccgctaca ataagaaccg
     4141 cgttcatcgg atatccgaac ctgcctcgcg gcgatcgatg aatccgggat cggattcaag
     4201 ccattcgcac gtgaagtgtt gggcctcata ccggagacct gacactcggt caacgcgtaa
     4261 gccaaggatc ggccgcgcgc tcagtgcagg ggcggcggcc ggcggcgcac ccagttgctc
     4321 gccgcgtcgt aggccgcgcc gagctggagg caggcgagtt cgccgtggtt gcgggcgacg
     4381 atctggatgc cggtcggcag gccggcgtct ccgaagcccg ccgggacgtc gagggccggc
     4441 aggccggaca tggtcaccgg gaccacaatc tgcatccacc gatggtaggt gtccatcgcg
     4501 tggccgccga cctcccgggg ccagcgcagg cccttgtcga acggaaagac ctgcgcgctc
     4561 ggcatgacca ggtaatcgta gttgtccatg aagcggcgga cggtctcgta ccagcgggtg
     4621 cgcccctcca gggcggcaac cacctgatcg gcggtgagcg caagcccgcg ctcggcctcc
     4681 cagatcgcct cgggcttcat ctgcgcccgg tggccgggct cgtcgtagag cggccggagc
     4741 gcggcggaga ccgacagcgc ccgcaacgtc aggaaatcgc gccagagctg ctccatgtcg
     4801 aaccgcggcg cggcctcctc gaccacgcag ccgatctccg cgaaggtcgc gagcgcggcg
     4861 cggccgagtt cgagcacccc gggatcgaac gggatctggc cgtcgaaatt cccgagccag
     4921 gcgatccgcg tcccgcggaa atcccgggcc agcgggctcg cgaaggccga cgggtcctgg
     4981 cggatcgtgt tcgggcagcg gggatcgtag ccggcctgga ccgacaacat caggccgata
     5041 tcggcggggc tgcgcccgat cgcaccgagc accgataggc ccgggctgaa cacgtccttg
     5101 gtctcgaccg ggatccggcc ccagctcggg cgcaggccgt agcaattgtt gaaggccggg
     5161 gggttgcgga gcgagccgcc gaaatcgctg ccgtcggcca ccggcagcag cttgagcacg
     5221 accgccacag cggccccgcc gctcgatccg ccggcgctct tctccggatc gtaggcgttc
     5281 ccggtcacac cgtagaccgg gttgaagctg tgcgagccga gcccgaattc gggaatgttg
     5341 gtcttgccga tgaagatcgc cccggccgcg cgcagccggg cgaccatgat cgtgtccact
     5401 tcggcaatcc ggtcggcgaa gatgggcgac ccttgcgtga acggcagccc gcgcaccgca
     5461 tcgagatcct tcacggcgag cggaaacccg tgcagcggcc ccacggcctc gccgcggacg
     5521 agcgcggcat cccgcgcctc cgcctctcgg aggagcgccg cgtcgtcctg gagcccaacg
     5581 atggcgttga cctgcggatt gagccggtgg atccgctcca ggtacgcccg catgacctcg
     5641 acgcaggaga cgacccggcc gcgaatggcg gccgcgagat ccacggcacc aagcgccgtg
     5701 atgccgtcct gtcgctcatc ctgcatggtc gatcgtctcc ctatcgcggt ccgcgccggc
     5761 atggccgagg cttggtgagg tcgatcacac gttttgtcgc gtgcgacggt ctaccactag
     5821 cgatagttgg ggagacaaga gatgtgcagg gattcggctg acgttcaagc ggccggcgtc
     5881 gcgcgcgcaa tgcgcggtcg ttcctgatcc cgtccccagg ctcagcaccg tcattgcgag
     5941 tatagcgaag caacctaggg cagcgcgcgc tcacggaatc tggcgtttcc ctgggttgcg
     6001 ccgctacgct cgcaatgacg gtggggccgg tgcgaactcc taccggcgcc ttatcagacc
     6061 accgcccaag gcagcgtctc atccccgcgg aacaccacca cggcggtgtc ctccacggcc
     6121 accgcctcga tcacgcggct ctcccgccgc tcgagggtga ccgtggcggc gttcggctcc
     6181 agcccgtgga accgcgcccc gttcagcgat gcgaacgcct cgaaacggtc cagcgcgccc
     6241 tcctcgtcga agacctgcac gtaggtctga agcgcgcttg gcccgcagaa cacgccggcg
     6301 cagccgcagg aggcctcctt ggcgccgcgg acatgcgggg cggtgtcggt gccaaggaag
     6361 aagcacgcct cgccggaggt ggcggccgca cgcagcgcca ggcggtgccg ctcgcgcttg
     6421 gccaccggca ggcagtagag gtgcgggcgc aggccgccct gaaagatgtg ggtgcggttg
     6481 atgacgaggt ggtggggcgt gatcgtcgcc gccacgcggc tccggttggc ccggaccacg
     6541 tcgaggatct cggccgtggt ggcgtgctcg acggtgacct tcaggccctg gtgccgggcg
     6601 agcagcggga tcaggctgcc ctccatgaac gccgcctcgc ggtcgaagat gtcgatctcc
     6661 ggatcggtcg cctcgccgtg gatcaggagc ggcatgccga tccgctccat ccgctccagc
     6721 acgggcgcga gcccgatcag gtcggtgacg ccggcatggg aattcgtggt cgcgccggcc
     6781 gggtagagct tggccgcgat ccagacgttt tctgcaaagc cccgctcgat ctcgtccgga
     6841 tcggtgtcgt cccgcaggta gcaggtcatc agcggggtga aatcgaggcc ggcgggcagc
     6901 gcggccagga tccgctcgcg ataggcgcgc gcggccgcca ccgtggtcac cggcgggacc
     6961 aggttcggca tgatgatgcc ccgggcgaac tgggccgccg tgtaaggcag caccgccttc
     7021 agcatcgcgc cgtcgcgcag gtggatgtgc cagtcgtccg gccgacggat ggtgatccgg
     7081 tcggccgcga tggaagcggg cggctgcgcg gcggggaaca ggtcggcgac gctcatcgct
     7141 ttcggctcct cagccctgac cgaaggagga gatgccgccg tgggccgacg accattcggc
     7201 cggcgcgtta aggaagctct cgacctcggt cagcgtcttc ggatcgaagg tgcccatctc
     7261 cttggcgacc gccagcacgt cccaccacgt agtcaggtag tgcagcttga tcccggtctc
     7321 ctgcatcagc gcggcgctgc cggggaagat gtcgtagtag aacagcacga agcagtgatc
     7381 gacctgggcg ccggcgtccc gcagggcctg gcaaaagttc accttgctgc gcccgtcggt
     7441 ggcgagatct tccaccagca gggtccgagc gccctccacc acctcgccct cgatctgggc
     7501 gttgcggcca aaacccttcg gcttcttgcg cacatactgc atcggcagca tcagccggtc
     7561 ggcgatccag gcggcgaacg ggatgccggc ggtctcgccg cccgcgacat gggtgagcga
     7621 ctcgtagccg atctcgcgca cgatcgtggc ggtcgcgaaa tccatcagcg tcgcgcgcag
     7681 gcgcgggaac gagatgatct tgcggcagtc gatatagacc gggctggccc agcccgaggt
     7741 gaacttgaac ggctcgtcct tgtagaaatg gacggcctgg atctccagga acatcttggc
     7801 cgcttcgcgg gcgatgatcg tccggtcgat gggcaggaac gacgtggtca tgcggcgtgc
     7861 gcgctccgct gggtgcgctc accgccggag gccgggccga ggagcgcgag gatgggaagg
     7921 cctgaccggt ctcctccgcc ctgtctccgc cagcgtcaac cctgaagccg acgctatccg
     7981 cctctcaggc cgcgccggcc ttggctcgca gctgcgccag gtgccggatc gccagggcgt
     8041 agccgtgcgt cccgaacccg gccagcaccg cggtcgcggc gagcgagatg taggaatgat
     8101 gccgaaacgc ctcgcgccgg tggacgttcg agatgtggca ctcgatcacc ggcacctcgc
     8161 aggtgttgag cgcatcgagg atcgccaccg aggtgtgggt gtaggccccg gcattgatca
     8221 cgatcccggc ggacccgacc cggaacgcat ggatcgcgtc gatcagcacg tgctcggcgt
     8281 tgctctggcg gaaatcgatg cccagcccga agccggcggc tgtctcgcgg cacagggcct
     8341 cgacatcggc caaggtctcg cgcccgtaga tctccggctg ccgcttgccg agcaggttca
     8401 ggttcggccc gttcaggacc aggatcgtgt caatcatcgt gttcctcgcc gccccacgtg
     8461 gccggcaccg aagcctcaat gcactgagac ctcactcgct tgctccccct cgcgccctca
     8521 tcctgaggcg cgagcgcagc gagcctcgaa ggagccatcg aggactcgcc cggcagactg
     8581 gagacctcct tcgaggcgac cgctgcgcga acgcgcctca ggatgagggc acgggttgct
     8641 tcgccccgtt gtggccgtgc ggggggcaag ggtcaaactg gctctcgcat gcgcctgtca
     8701 cccgatgggc gatgttccgt acagagaccg tctcatccgc ccaacaggtt cagtttcgcg
     8761 gcgcgcgccg ctatcccggg tgcgaccgcg aatagaaatc agggaggaca cgccatggca
     8821 ggatcccgca gcgcaacgcc cgtggtgatc gcggtggcga tcaccggctc ggtgccgcgc
     8881 aagaaggaca acccggccgt gccggtcacg gtggccgagc agatcgagtc gacgcagcag
     8941 gccttcgagg ccggcgcgac gctggcccat atccacgtgc gcaacgacga cgaatcgccc
     9001 tcctccgacc ccgacaagtt cgccgccgtg caggaggggc tgcgcacgca ctgccccggg
     9061 atgatcgtgc agttctccac cggcggccgc gggcgcgatc ccgccgcccg ggggctctcg
     9121 ctgaagcacc gccccgacat ggcgtcactc tccaccggct cggtgaactt cccgaccatc
     9181 gtgtacgaga acggcgccgg cctggtgacc gatctggcga gccagatgaa gcagcacggg
     9241 gtgcggccgg agatcgagat cttcgacctg tcgcacctgc acggtgccaa gaggctggtg
     9301 gaggcgggcc tgatcgacgc gcgcccgcac gtgcagttcg tgatgggcgt ccagaacgcg
     9361 atgccggccg aggagcacct gctcgacatc ttgctcgccg agacgcggcg gatcctgccc
     9421 gacgccacct ggaccgccgc cgggatcggc cgcaaccagg cggtcgtgat ggagtgggcg
     9481 cttgcccgcg gcgccgatgc ggtccgcacc ggcctggagg acaacatccg ggtgacgaag
     9541 gaccggctcg cggcgagcaa cgccgagttg gtcggcctcg cagccgcggc ggtccgcagc
     9601 cacggccgca acgtcgccag ccccgccgag gcgcgggccg cactgggtct gggctgaacg
     9661 gaatcatatt ccgcaccccc gtcttggacc gcgtcaaatc tcgttggccg acaagcgatc
     9721 actcgcgaag cctttcgggc atcacggctt ccgggcgacg atggcgtgca gtctaccgac
     9781 ggagcggtcc tgatcgacga ggaagccaat cgcctgcaat tccttcgcca cggcagcagg
     9841 ctgaagccgc agcttccgat agctgctttt gcgcagcgtc caaccgtcat tgtcgcggat
     9901 atggatgata tcggtcacga cgacgctttc aggctcgtag tccagtgcgc agaccatcaa
     9961 acgctggtcg tccgcccgaa ccggaatgaa gcgatctaat cctgtcagtt cgagcgaaag
    10021 atcgcgaaac gtcaggacca aacgacctgt cacacgtagc acgtcatgcg catcgcggaa
    10081 gagcttcgat acgtcgccgc gatcgtcgag atgcgtgagg gtatcgccca tacatacaat
    10141 cgcatcgacg ctttcgcgct caaccaatgt cgcgaagctg cgcatatcgg ccaatcgcgg
    10201 ttcgatagga gttcccgctc taagagcatt caattcatcg agcagagcgc gacagttatc
    10261 gattgcaata actgattcga agccgagatc gctgagagca aagctctggt agccaggccc
    10321 gcaaccgaga tcgatggctc gaccattcgt tcgtgaatat attccaagat cccaaagcag
    10381 attccgctgc tcggaaacct tttcagcgaa cgatgaaccg ttcatccatg agtagtgatc
    10441 tgcaagaaga ttgtcgtaat gggcttgcac atggctcatc agaagctccg tgccaggctt
    10501 tttcgaacgc attacattcg ttcagggctg cttgtcgaga ttgcgttccg agagccgcgt
    10561 atctcccagc gcctttcaac cgatcgccga cacggcccag aagcccatct tctcacgggc
    10621 cggacggcgt gctaacggtc cgcccgcgcg ggtgtagctc aatggtagag cagcagcctt
    10681 ccaagctgaa tacccgggtt cgattcccgg tacccgctcc acgccgtctc accatctgaa
    10741 gccgccggca gcggcaggat atcggatcgg tcggcgcggg cctcccagcc gcggacgccc
    10801 tcaacgatcc atcgcaaaat cccgctcgcg gaaacgctct cggtcgatgg tcgcgcccga
    10861 ccgtcggacc tgtgagggcg tgaggccgaa gcgcttgcgg aacgtgcggt tgaagtagga
    10921 caggtcgccg aacccgacat cgaaggcaat ctcgctcacc ggccgggcat cctcggcatc
    10981 cgtcaggcgc tgcatcgccc ggtcgaggcg tcgggcgagg acaaagcccg agaaggtctc
    11041 accctctgcc tgaaacatcg cctggacctg ccgactggag atctgctggg cttgcgccac
    11101 ggcctccagg ctcaggtccg gccggccgag gcgctgctcg acctcagcct tgagcgcctg
    11161 gattcgcagg tcgcgccgac tcgggccggg cgcggaaatc gcggggcccg gctcgcgcac
    11221 gatgaaggcc agcagctgcg cgaggtgctc gcggacgaga tctgcgatgc ccggggcgcc
    11281 cacggggatc aggccccgca ggaggctcgc gccgtagacg gtcagcgtct gcaggcccgg
    11341 atggtcccgc ccgatccgcc ggatgtgccc tgtctccagc gcggcgaggg gaccggtcag
    11401 ccgctcccgg tcgatcgcca ggaggtcgat ccggtcgacg cccagcgcgt cgaagagggc
    11461 gccccggctc gtggctacca gcagtgcgtc cctggagcag caggcgacct tgcacccgcc
    11521 ctgggtcacc tcgagtcgcc cgattgcggg ccgcaccagc agcaggcgct cgcccgggcc
    11581 ctcgtcgcgc caggagcggg acggctcgaa caccgaggcg atgccgaggt ccggaacgat
    11641 gcgaatcgcc gtccggcccc ggaacgggag ggaatccgag tcctcgcgcg tctccgggac
    11701 gatgccggct gccgccccgc gggtcgcagc ctgcactgcg gcgctcatcg cggcgtccat
    11761 accgggcccc tcgtcggcgt ggcgaccagg caacgtcgtt tcgtcatcgc gccccctcgc
    11821 cgcgtagctg cgcagcagtc cgtactcttg cgcgcccgag tccaagcggg agcgaaatca
    11881 tcatgttaga gcggcctaga gatgtcgaga ctttatgcat cctcgaccaa tcgtctcggc
    11941 gctgaaagtc gcgataatat cgatttagac aaattttaaa ctgggcggac gccgatgtct
    12001 cgcgttctct acacgcagaa tccggcccgg cagttttgga aggcgtccca acgcggacgc
    12061 gcaggggtgg gtctgacaag catgcgtacc attcgtctcg tcgcgatcct cggtgcgggg
    12121 actgccctgg ccgggccggc ccgggccgag accgccgcac ccgtcgtcgc cctcgacgaa
    12181 atctctgtga cggccacccg cgcgccgcgc cggatcgagg acgtgccgca gagcgtccag
    12241 gtcgtcgacc gcgaccagat ccgccagcaa ctcgccctga cctcaagtcc ctcggccgtg
    12301 ctctcgaagc tggtgccggg attctcggta ccgaacggca cgatctccag cgcctcagaa
    12361 agcttccggg gccgcaacct cctggtgctg atcgacggcg tgccggtgaa tacgccgctg
    12421 cgcgacgtct cgcgcatcct caatctgatc gacctcaatt cggtggagcg gatcgaggtg
    12481 gtggccggcg cctccagcct ctacagcgcg ggcgccaccg gcggcaccgt gaacttcatc
    12541 acccggcgcc cgacggacgg ggctccggtc gtcacggtca acacggcgat ccggaccttc
    12601 acggccgacc cggttcacgg cgtcgcgccc gagacatcga tcagtgtgac cggcaaagtg
    12661 ccggacggcg tcgattacgc gttcaccggc tccggtcggt tcgccacccg caccttcgac
    12721 ggcaaggggc gggaattgcc ctccgacggt cagctcggcc agggcggtgc cgaccgcttc
    12781 cagctcggca acatcaacct gcggctcggc tacgacctcg atctcaccaa acgcgtcgag
    12841 ttcggcctca cccagatcct gctcaaccag gatccgcgct acctcaccga ttacagcggc
    12901 tccttcgccc ggcccgacta cgcgcgaagc tatatcggcc tgccggtcgc cgaggatacg
    12961 cgctcactgt acctacgcta tacggatcgg gatacgccgc tcggcagttt ctcgatcctc
    13021 ggtttctaca acgacatcaa caagcgcttc aattattcgc agttcgccta tccggccaac
    13081 ccgttcgtca cctactcgtt catccccacc gcgcccacga gcctggccaa ccagaccgcg
    13141 ctcgccaccg agcgcggcgg catcaacctc accctcgaca ccgacctgag cgtcctcctg
    13201 cccgggctga agctgacctg gggctccgac ataatctcgg aatcaacccg gcagcgggcg
    13261 cgggacggca ccgacgtgtt cacgcccctg cagcagaaca gctacgccgg cttcgccctg
    13321 ctccagctgc cgatcggcga gcggctgacc gtacgtgccg gcatgcgcta cgagcacttc
    13381 gacctcgacg tcgcgggctt cacccggcca acgaccttcg cggcaagcgc ggcgcgcaac
    13441 gccctgggct actcgacctt cgtgctgcca gccctcaacg tcaccggcgg caagttctcc
    13501 tactcagccc cgaccttcaa cgcaggcgcg accttcaacc tgctgccggg catcgacctc
    13561 tacggcggct tcagccaggg ctacgcgctc gccgatatcg gcgccttcac gcgccgggcc
    13621 ggcctgtccc tcgcctatgc ctgcccgatc tcccgtccgt tctgcctgcc ggcgggcacc
    13681 accatcgcgt attccagcat cgccccgcag gcgcagatcg tgaactccta cgatttcggc
    13741 gtccgcggcc ggagcgggat cttctccggc agcctcggcg ggttcgtgtc gacctccgac
    13801 gacggcacga cgttcgaccc gctcaccaac aagctgagcc agcagaagga gatgatctac
    13861 ggggtcgagt tcaccgggaa cgcgcaggtc acggagcaac tgaatctcgg caccgtactc
    13921 ggctaccgcg agggccgcta cgacaccaac aaggacgggc gcctcgacag ctacctgccg
    13981 aacaaccgca tcggcgcccc cttccacggc acgctatcgg ggacctacct gttcgcgaac
    14041 ggcgtctcgc tccgggtcga gggtgagggc ttcagcggcc gcgacgcccg catcgacctc
    14101 atcggcaccc gcttccgctt gaaggacgcc ttcacggtga acgccgcgtt cggcgccccc
    14161 ctggccgggg gcgagctcta cgcatccgtc gataacctgt tcgaccgtgc ctactggaat
    14221 ccgaccgcga cctcggtgcg caacctgacc gtcttcgggc tcgggcgcac cgtcaccgtc
    14281 ggctaccgca ggacgttctg agggatggtc gccctcgaag aggccgacga cctcatggtc
    14341 ctgcgctatc tcggtccaac cgagccgggc gacgagaccg cctacctcga cgccctggag
    14401 caggtgggcg cacggactga gccgttcgcc ctgatcctgg tgctcggcgg cgtcggcaaa
    14461 ctttcggcgg cttccgaaaa ggcccaggct ctctggttca agcgcacgcg cgccgacctc
    14521 gagcggcact gccgcggcct cgtgatcgtg cggccgggct tcgaggaggc gggcgccgac
    14581 gtattccgcc ggctctggaa cttcccgatc gagatcgccc ccgacgagcc ggccgcccgg
    14641 gcctccgcac gggcctatct ctcatgagcg ccgcctcctc ggcacccgcc gccgtggccg
    14701 tcacggccga cgggcggcgc gagcggtact cgctcttcgt ggtgctcgcc gccctctaca
    14761 tggcgcaggc gatcccctcc tacctgatcg ccgctgcgct cccgccgatc atgcgcgagg
    14821 ccggcgtgtc ccgggcgggg atcggctatc tgagcctcct gttcctgccc ctcgtgctga
    14881 agttcctctg ggcgccgctg atcgaccgtg tgcggccctt cgcgcgggcg caccgggcgg
    14941 ggtgggtggt gatgacccag gtcggcgtga tcggttgcat cctcgcgatg ctgccgctcg
    15001 gccccaccaa cgtgcccggg atcatcggcg tcggcttcct cgccgcgctg ctgatcgcga
    15061 cgcaggacat cgccaccgac ggctacgccg tgaagcggtt gcggccggaa gatcgcgcca
    15121 tcggtaacgc catacagggg ggttcggtcg ccctcggggt ggtggtcggc ggaacgctga
    15181 gcctcgtcct ctaccatcat gtcggctgga ccgggatgct gctgagcgcg gcggccttct
    15241 cggtgccgcc gctgctggcc gccttcgcca tgcgcgagga agcgcccgag accggcgcca
    15301 ccgcgccgcg gccctcgatc cgggccttcc tgcggcggcc ggaggtgcac accatcctgt
    15361 gggtggcgct cacctaccgg gtgagtgagg ggctcgtgaa ggccatggag ggcgcctacc
    15421 tggtcgatgc gggcgtaccc ctcgaccgga tcggctacct gtccggcgtc tcggcgatga
    15481 ccgcggggct cgccggctcc ggcgtcgcag cgctgctggt ccgccgctac ggcacggccg
    15541 cgaccctcgg cctgctgggc gggctgcgga ctctctgctt cgccctgttc acggcgcatg
    15601 ccttcggggc tgtcgtcggc ctgtggcctc tgttcggcgc ggcagggttc cagaccctga
    15661 tccgctacat ggagatcgtg gcgctctaca gcctgttcat ggcggtctct tcagcggagc
    15721 agccgggcac cgacttcacg atcctcgcct gcgcgcaact cgtggtctac ctcgtcggct
    15781 cactgatctc gggcaagctc gccgacctcc tcggctacgg cgccctgttc gggctcgcga
    15841 cgttcctttc cggcctcgca acgatggcga ccgtccggct gctcgggacc ggccgcaccg
    15901 gtcaggccac cggatgacgg gggtcgtccg ggcgaagccg cacggcggca acgatcaggg
    15961 caaggcccaa cgtcgcgcag gtccagaacg gcagcgcggg cgcgatccgg aacgccgcgc
    16021 cgccgcagag ggctccgatc ccctggccga gcacgtggac gctcgcgagc cagccggcgg
    16081 ccgcggcctg ggcgtgcccg ggcatccggg cgaccagggc ggcggtgtaa tgcggggtcg
    16141 ccagggcaat gccggcgccc accacgaccg tcccgagcac ggcgacccag gcggcgggag
    16201 cacaggcggt cacgcctgca cccgcggcga agcctgcaag cccgaggctg agattgcgcc
    16261 gcaggttcgg gccgaggcgc ggcaccagga cgagttgcgt caggatcatc gtcaccgcga
    16321 cgagcgcgaa ggtcgcgccg gcaagacctg cggcgcccgg cgcgtcgagg ttgaagcgct
    16381 tctgcaggaa caggccgagc acgatctgga tctggccgag gccgagggtc agggcgaagc
    16441 cgatccccat cagcggtgcg gccgcgcgca ggacgccacc gcgatccgcc cccgccgccc
    16501 tggcgccagg gctgccgccc gggaggtcgg gcgcggccag gagcagcaac gggctcgccg
    16561 ccagcaccgc caggggcgcg gcggtcccga acaccccgac gcccatcgcc agcgagccga
    16621 ggatgcgccc tgccgagagt ccggcaccga gccggccgag cgccgccggg cgtgccgttt
    16681 ccgccaccga ccccagcacg gcagcctggg catgcggcat caccccggcg gctcccgctc
    16741 cgtaggcgat ccgcgaggcg acgagcagca ccagggctcc agcgacgggc agggccggca
    16801 ccgtcagggc cagggcgaac agaccatggc cgagcgccat cagggcggcc agtgccgcga
    16861 acagccggcg cagacgcaaa ccggtccccc agttccccca ggccggcgcg cagaccagga
    16921 atgcgaccgc cccggcgaag gcgacgcccc ccatcgcgac cgcatcgagc cctgtgcgct
    16981 cggctaccac ggggacaagg gcgagcacgg ccgattgtcc gaaccccacc gaggccgcgg
    17041 cgagagatag tcgcccggcc actccagacc cgggagtgcg cacatcgatc cgaaccatga
    17101 cacctccgtc cgcgcacgga tcttattggc gcgataaccg gcatggcaac cttcacacca
    17161 taaatttaaa atagttctat agtattaatc atctattgcg ccccattttt cttttgtcta
    17221 ttggcaatgc cgcgatatga agagggtcgt atggttgaag ccgacatctc atgtgccgac
    17281 gttgcttccc aggtatcggt gcgcagcttc ctgaacagcc tgatgcggga atgggccggc
    17341 tggactctgg cgaccgccga ggcgcgcgaa gacgatccga cgcgtcccgt gttgcggatt
    17401 tcgctgccga gccgagcttc ggtgatcgag atcgcggtca cccatgtctc gtccgtcggc
    17461 cagcacatgt tcaggctgcc gttccgcgaa ctgcgccccg gcgagccgcc ccgcatcatg
    17521 gcgttggcgg cgttcgcggc agcggtggcg aacgagccgg ccatcgtcgg accggcagca
    17581 ccgcaggccg cgccgatttt cctgcgccgc ctctttcaga gcctcgccac cgtcgaagac
    17641 atcctcgtcc gcgcccctgc accgggcatc ttcctgagcc gcgacccgag cttccgcgag
    17701 gccgagcgcg cgctccggtt cggccattcc gtgcatccga ccccgcgcag ccgggacgag
    17761 ttcacgctgg ccgattcccg cgccttcgcg ccggaatacg gtcggggctt tcccttgcgc
    17821 tggtggtcgg ccgcgccgga gacggtcgtc cagggttcct cgcgggcaac gagcgcagcg
    17881 gacctctgcg cggacctcgc cgctgaagat gccggcttcg atccgacgat attcgccgcg
    17941 agcggggggc gcgtgctgct gccggtccat ccgtggcagg cggcccgcct cgcgctcgat
    18001 ccggagatcg acgccctgtt ccgcaccggc cgcctgcgcg accacggcca tgccggcggg
    18061 ccgtggtacg cgaccacatc gctgcgcacc ctctacgcac cgggtgcgcg cttcatgctc
    18121 aagcattcgc tgagcctcag gctcacaaat tcgctgcgcc tcatcaaaag cgtcgagtgc
    18181 gcgcgcggcc tcgtcgtgga tggggtgctg aacgggccgg tcggcgccga gatcgccgcg
    18241 cgctggccga gcttccacgt cctcggcgag ccggcctatc ttgcgctgcg tggcgccgat
    18301 ggggccgcgc tgccgcagac gttcgtggca ttgcgggaca acccgttcca cggggcggac
    18361 gagcggccgg ccgcggtgct ggccgctctc tgcgagatct atcccgatgg gcggggcagc
    18421 gggctggccg acacgatcct gcgcatcgcc ggccgtaagg acgcggacgg cgatggcccg
    18481 gtcgaggccg ttgccctgcg ctggttcgag cgcttcctca ccgtcacggt cgggccgatc
    18541 ctcgagatcc agtgcgcgct cggccttctg ttcggcgcgc accagcagaa cctggtcctc
    18601 gaactcacgg atggctggcc ggtccggacc ttcttccgcg actgccaagg tacgggtttc
    18661 gtgcgtgaat tccttccggc cctccgcgag gccgcccctg ggctcgacct cgaggccggg
    18721 cacctcctga cctccgggga ggctgcgcgg gtcatggcct actacctcgt ggtcaacagc
    18781 gtcttcgccg tcatcggagc catcggcatc gccggcctgg cgccggaggg cgccctcatc
    18841 ggggccctgc gccgattcgt cgaggcgctc gccgggaagg acctccggga caagacctgc
    18901 ctgcgcctgc tgctcgacgc cccggccctg ggcagcaagg gcaacttcca gatctgcttc
    18961 cgtaacctca acgagaacac cgacgtgacc gaccctctgg cgagctacgt tgaccttccg
    19021 aaccccctcg cggctccgtc cgcccgcgca ggcgcccggc catgacggtg cgcgcccgca
    19081 tcgatgccgc cgccgggacg gcgctggacg gctggaccgg gacgagccgc cactgggccg
    19141 ccaccggcga cgatttcgtg atcgaaagcc tgccgtccga tgccagcagg gtccggctga
    19201 ccttatcgcg cggcggcgac ccgatcgcgg aggccgaact gcgctccggc gcggacgaag
    19261 ctttcctggc gctcaccggc tcggccggcc gtcatcccgc cgacgcgccg gtcgtggcgg
    19321 ccctggtcga ggccgcgttc cagcggtgcc cggaggccgg gcggctacgt gtcgccggcc
    19381 tcggcagcgc ggcgtccctg cgcgcactgg cggcgcagtc tgagggtgac ccggccgcgc
    19441 ccgacgcggt cgtggagcgc gcgctgttct atcagcttcc cctgctatgg ctggcagccg
    19501 gaacgcgggc cgcctacccg ctgatccgct cgcggatcgg gccgcaggac cgtctaccgc
    19561 ccctgcgacc gccgcagccg aacggctcgt tttaccggcg ttggctgccg cagctcggca
    19621 cgaccctgtc gtttcgcgcc atagaccggc ggcacga
//
