LOCUS       c00017_NZ_CYYA..       12908 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CYYA01000017.1 Eubacterium ramulus strain 2789STDY5608891, whole
            genome shotgun sequence.
ACCESSION   NZ_CYYA01000017
VERSION     NZ_CYYA01000017
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:59:48
            Original ID  :: NZ_CYYA01000017.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12908
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12908
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[647:2908]"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      648..2908
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
     cand_cluster    1..12908
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /kind="single"
                     /product="fatty_acids-unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12908
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="fatty_acids-unassigned"
                     /region_number="1"
                     /rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /tool="gutsmash"
     CDS             complement(3..455)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.9e-39, bitscore:
                     125.8, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFGLSKKHEMARSLFKEFAENEVKPLAQEVDETEKFPTGTVEKM
                     AKYGFLGIPVPKELGGQGCDILTYAMCVEELSKVCGTTGVIVSAHTSLCVDPILTFGTP
                     EQKEKYVPDLASGKKLGAFGLTEPMAGTDAQGQQTKAVLDGDEWVLN"
     CDS             complement(648..1487)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_2"
                     /sec_met_domain="HCDH (E-value: 1.5e-38, bitscore: 123.3,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 1.6e-63, bitscore: 205.8,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGIIGAGTMGSGIAQAFAQTEGYEVYLCDINDEFAANGKKKIA
                     KGFEKRIAKGKMDQDKADAILAKITTGTKDICTDADLVVEAALEDMAIKKQTFKELQEI
                     VPADCIFATNTSSLSITEIGAGLDRPVIGMHFFNPAPVMKLIEVIQGANTPDDLRDKIV
                     EISKKIGKTPVQVNEAAGFVVNRILIPMINEGICVLEAGVASVEDIDAAMRLGANHPMG
                     PLQLGDYIGLDICLAIMEVIYSETGDPKYRPAPLLRKMVRANKLGCKTGVGFYDYSK"
     CDS             complement(1721..2908)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg17_3"
                     /sec_met_domain="Thiolase_N (E-value: 7.3e-100, bitscore:
                     325.5, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 3.2e-50, bitscore:
                     160.9, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKVVLAGACRTAIGKMGGQFGNTPAVELGSIVIKEALKRAGVA
                     PEQVDEVMMGCVIQASQGQNVARQASIKAGIPNEVPAFTLNVVCGSGLKCVNEAANMIM
                     AGQADIVVAGGMENMSMAPYALKKARFGYRMNNATMIDTMVNDALWDAFNNYHMMITAE
                     NICDQWGLTREELDEFAAVSQQKAVAAQESGAFDDEIVPVPVKMKKETVMIAKDEGPRP
                     GTTAESLSKLKCCSGKEGGLVTAGNASGINDGAAAIVVMSEEKAKELGVKPMATFVAGA
                     LAGCAPEIMGIGPVPATRKALKIAGLEMDDIDLIEANEAFAAQSVAVQKELGFSSDILN
                     VNGGAIALGHPVGASGCRILVTLLHAMQKRDVTYGLATLCIGGGMGCATIVKKEA"
     CDS             complement(3500..6703)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CPSase_L_D2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_4"
                     /sec_met_domain="CPSase_L_D2 (E-value: 4.7e-84, bitscore:
                     273.0, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKRSDIKKVLVIGSGPIVIGQAAEFDYAGTQACRSLKEEGVEVC
                     LVNSNPATIMTDKQIADQVYIEPLTVDVLKQIILKEKPDSVLPTLGGQAGLNLGMELAE
                     SGFLEENGVKLIGTTAETIFRAEDRQAFKDTMEKIGEPCAASLVVNTVEDGIKFTNTIG
                     YPVVLRPAFTLGGSGGGIAHNEEELVEILSNGLRLSRVGEVLVERCIAGWKEIEYEVMR
                     DANGNCITVCNMENIDPVGVHTGDSIVVAPSQTLGDKEYQMLRTSALNIISELNITGGC
                     NVQYALNPDSFEYCVIEVNPRVSRSSALASKATGYPIAKVAAKIALGYTLDEIKNAITG
                     KTYVSFEPMLDYCVVKIPRLPFDKFITAKRTLTTQMKATGEVMSICTNFEGALMKAIRS
                     LEQHVDSLVSDEYLTLSYDKLIERLKVVDDRRIWVIAEACRRGVSYDTIHEITKIDKWF
                     IDKIAILVEMEGRLRSEALTVDLLREAKRIEFPDKVIAQLTGKDEDYIKNMRYENGITA
                     SFKMVDTCAAEFAASTPYYYSCFDGENEADGTAKKKKVLVLGSGPIRIGQGIEFDFCSV
                     HCTWAFSKAGYETIIINNNPETVSTDFDIADKLYFEPLTPEDVENVVNIEKPDGAVVQF
                     GGQTAIKLTESLMKMGVPILGTKAEDVDAAEDRELFDEILEKTNIPRAAGDTVYTAQEA
                     KVAANRIGYPVLVRPSYVLGGQGMHIAFNDDEIVEFIDTINQIAQDHPILIDKYLMGKE
                     IEVDAVCDGTDILIPGIMEHIERTGVHSGDSISVYPAPTISNHVKETIVEYTKRLARAL
                     HVVGLINIQFIAMNEEVYVIEVNPRSSRTVPYISKVTGIPIVDLATKVILGETIKGMGY
                     KPGLAPEADYIAIKMPVFSFEKLRGAEISLGPEMKSTGECLGIAKNFNEALYKAFIGAG
                     IQLPKYKRMIMTVKDSDKEESVGVAKRFEALGYTIYATRSTAKYLQDHGVNARRVNKIS
                     QESPNVMDLILGHKIDLVIDTPTQGRDKSRDGFLIRRNAIETGVHCLTSMDTANALALS
                     LETANDQMTMIDIATVKNL"
     CDS             complement(6703..7773)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_5"
                     /sec_met_domain="GATase (E-value: 3e-47, bitscore: 152.7,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAFLILEDGTVFTGTSIGSTKSVISEIVFNTSMTGYLEVLTDPS
                     YAGQAVVMTYPLIGNYGVTPDMESAQPWPDGYIVRELSRIPSNFRCQGTIQDFLKEHDI
                     PGIAGIDTRALTKILREKGTMNGMITTDENYKLDEILPQLHVYNTGNVVDKVTCSEKKV
                     LKADGYKVALLDFGAKNNIAQSLHKRGCEVTIYPAHTTAEEILSSDPDGIMLSNGPGDP
                     KACTDIIKEVKKLYDSEVPIFAICLGHQLMALATGADTYKLKYGHRGGNHPVKDLETGR
                     VYISSQNHGYAVDADSLDQAVAVPAFTNVNDGTNEGLKYTGKNIFTVQFHPEACPGPQD
                     SGYLFDKFIEMMGGQK"
     CDS             complement(8130..9410)
                     /locus_tag="ctg17_6"
                     /transl_table=11
                     /translation="MIDIKFLRENPDIVKQNIKNKFQDHKLGLVDEVIELDASSRTVQQ
                     EADDLRANRNRISKQIGALMGQGKKEEAMALKEQVAKDAERLTELEAQEGELQEKIKKI
                     MMTIPNIIDPSVPIGKDDSENVEVERFGEPVVPDFEIPYHTEIMEKFDGIDLDSARKVA
                     GNGFYYLKGDIARLHSAVLAYARDFMIDRGFTYCIPPYMIRSNVVTGVMSFDEMDAMMY
                     KIEGEDLYLIGTSEHSMIGSFIDTMIDEEQLPKTLTSYSPCFRKEKGAHGIEERGVYRI
                     HQFEKQEMIVVCKPEDSMMWYEKLWQNTVDLFRSLDIPVRTLECCSGDLADLKVKSVDV
                     EAWSPRQKKYFEVGSCSNLGDAQARRLKIRVKGADGKKYLAHTLNNTVVAPPRMLIAFL
                     ENNLNADGTVNIPKALQPYMGGKTKIE"
     CDS             complement(9549..10802)
                     /locus_tag="ctg17_7"
                     /transl_table=11
                     /translation="MLENIRLSFQGIWSHKMRSFLTMLGIIIGIGAIIAIVSTIQGTNE
                     QIKQNLVGAGNNAVTVQLYQDEWTYEMDYNGIPDGVPVISDDTMQQILAVDGVEEASRY
                     TSRQGYDTVCYGNTSLSGGYVMGVDANYLDTCSYTIKEGRGFDSNDYAKYRKVAILDRD
                     SASSLFQGADAIGKTIEIQGEPYIVVGIADKKDGFEPVINSMDDYYTYMQDSSGRVFIP
                     SATWPIVFQYDEPQSVVLKATDTDSMASAGQAVADILNANLSVSDSTIQYKGQDLLKQA
                     QDIQELSQSTNRMLIWIAGISLLVGGIGVMNIMLVSVTERTQEIGLKKAIGAKKSHILG
                     QFLTEAAVLTSLGGIIGVIAGIVLAEVISKVSEMPVVISIPAAIIAVGFSMGIGIIFGL
                     LPSYKAANLKPIDALRRE"
     CDS             complement(10821..12365)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg17_8"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 1.9e-08,
                     bitscore: 26.0, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNRKVMKRVLVIAIVAAIAGGSIGTGVYVQRAKMTAEVMSVADL
                     NSGYWGDDVNSSGMITNDYSQSVEITNTDEIKEVYVKEGQQVQKGDKLLALDTTVASLN
                     LQGKQLEVENLNNQITIAQNDLKKLKNTKPYVEPANPVTPEPDIPHVQEMAGNAYNYIS
                     GTAVPYNQNSADGSEENPYRYLCTESAYVTGDFLSQLAEEKTYAVFEIRENNEVSGELV
                     TAWEVDGAQIVVPDGNTKWSVYDHSQISNDASEAEDDSSVVNDRISDEGGYTQAELNDM
                     IAEQEKKIKELDLNKRKAELEVEKLKAKSSDGMIYATVTGIVKNLQDKDNLPNDGTPFM
                     EVTGSEGLYVTGGISELLLDKVKPGQMVSVSSWESGSSCEAEITEIKNYPSTDVSSYGE
                     GNNNVSYYPFVAYIEDTSGFRNGEYVDLTMTVSDDETGSSLYIFKGYVRTENGKSYVLK
                     ADENDRLVKQYVKTGRIIYGDTIEIKAGLSEDDRIAFPYGKTAKEGVRAVDSDGSY"
ORIGIN
        1 ccgttcagaa cccactcatc gccatctaaa acagcttttg tctgctgacc ctgggcatct
       61 gtacctgcca tcggctctgt cagaccgaaa gcgcccagtt ttttaccgga agcaaggtcc
      121 ggaacatatt tctctttctg ctctggtgta ccaaatgtaa ggattgggtc tacacaaagg
      181 gatgtatgtg cagatacgat aacacctgta gtaccacaaa cttttgataa ctcctctacg
      241 cacatagcgt atgtaaggat gtcacaaccc tgtccaccga gttccttcgg tacaggaata
      301 ccaaggaagc catatttagc cattttctca acggttccag ttgggaattt ttcagtttca
      361 tcaacttcct gagcaagtgg ttttacttcg ttctcagcga attctttgaa aaggcttctt
      421 gccatttcgt gtttcttact taatccgaaa tccattttat acttttcctc catttttagt
      481 gaagcacagt caaaactcca aacgacacca aagacatgtg tagcgaaatg cacatgtctg
      541 gcgccactct ccgatatgaa catcggtatc agtcattttg actgcctact tcttatatat
      601 cttataagga ctatacccct tataattcga gagtaattat tctattctta tttgctgtaa
      661 tcgtagaaac ctacgcctgt cttgcagcca agtttgtttg cacgtaccat ttttctaagt
      721 aatggagctg gacgatactt aggatcgcct gtctcagaat agattacttc catgatagca
      781 aggcagatat caagaccaat gtagtcacct aactgtaaag gtcccattgg gtggttagca
      841 cctaatctca ttgctgcatc aatatcttct acgcttgcaa cacctgcttc taatacacag
      901 ataccttcgt tgatcatcgg aataaggatt ctgtttacta cgaaaccagc tgcctcgtta
      961 acctgaaccg gtgtcttacc gatttttttg gaaatctcaa cgattttatc tcttaaatca
     1021 tccggagtat ttgctccctg gattacctcg atcagtttca ttactggtgc cggattgaag
     1081 aaatgcattc cgattaccgg tctgtcaaga cctgcaccaa tctctgtgat ggataatgaa
     1141 gatgtatttg ttgcaaaaat acagtcagcc ggaacaattt cctgaagctc tttgaatgtc
     1201 tgttttttga ttgccatatc ctctaatgct gcttcaacta ctaaatcagc atctgtacaa
     1261 atatcttttg tacctgtggt aattttagca aggattgcat cagctttgtc ctgatccatt
     1321 ttgccttttg cgattctttt ttcgaatcct tttgcgattt ttttcttgcc gtttgcagca
     1381 aactcatcat tgatatcaca taaatatact tcatagcctt ctgtctgtgc aaaagcctgt
     1441 gcgatacctg atcccattgt tcctgctcca ataataccaa ctttcatgat atgtcctcct
     1501 taaaatgaaa atatatacta acatgaaaca tagcgactgc catacccaaa caatcttgtc
     1561 catagattag tcacacatat ctaataatgt ctgtgctttg ccgtaactat gttaaattac
     1621 taacaaagca atgtttaaaa tatctccgac actttcgcat gtcgcaatca tgccggagat
     1681 aaatccggat ttttaaatcc ttttaaaaat caaattttaa ttaagcttct tttttaacga
     1741 ttgtagcaca acccattccg ccaccgatac acagagtagc aagtccgtat gtaacgtctc
     1801 tcttctgcat agcatgaagc agtgtaacaa ggatacggca tccggaagct cctaccggat
     1861 gtcccagtgc gatagcacca ccgtttacat ttaagatatc agagctgaag cctaactctt
     1921 tctgtactgc tacagactga gctgcaaatg cctcatttgc ctcgatcaga tcgatatcat
     1981 ccatctcaag accagcgatc tttaatgctt ttcttgtagc cggaaccggt ccgataccca
     2041 tgatctccgg agcgcatccg gcaagagcac ctgctacgaa tgtagccatc ggtttaacac
     2101 caagttcttt tgctttttct tcgctcatta caacgattgc tgcagcacca tcattgatac
     2161 cggaagcatt acctgctgta acaagtccgc cctctttacc ggagcagcat tttaatttag
     2221 aaagtgactc agctgttgtg ccaggacgcg gtccctcatc ttttgcgatc ataacagtct
     2281 cttttttcat tttaaccgga acaggaacga tctcatcatc aaatgctccg gactcctgag
     2341 ctgctactgc tttctgctgg gaaactgctg cgaactcatc cagttcttca cgtgttaatc
     2401 cccactgatc acaaatattc tcagctgtga tcatcatatg gtagttgttg aatgcatccc
     2461 ataatgcatc atttaccatt gtatcaatca tagttgcatt gttcattctg taaccaaaac
     2521 gagctttctt taatgcatat ggagccatag acatattctc cataccacct gctacaacga
     2581 tatcagcctg tccagccatg atcatgtttg cagcctcgtt tacacatttc agaccggatc
     2641 cgcatactac attcagtgtg aaagccggaa cctcattcgg gatacctgct ttgatagatg
     2701 cctgacgagc tacgttctgt ccctgggaag cctggataac acatcccatc ataacctcgt
     2761 caacctgttc cggagcaacg cctgctctct ttaatgcctc tttgataacg atggatccta
     2821 attcaacagc cggagtattt ccaaactgtc cacccatttt accgattgca gtacggcaag
     2881 cgcctgctaa tacaactttc tttgccattt ttttcttctc tccttcttga ctttttaaat
     2941 atacctctag taattatgtt aaaagaataa cgctagacaa tattatttta gcactatcat
     3001 ctaatttttg caacgtctcc ttcgtcattt ttcctaaaat ttaaaaagga ttttcgtaca
     3061 cttttgtcat ttttttaaca tagtcgaaag ggtgaaaagt catctaaaag actgttattt
     3121 ttttaacata gtctccaaaa aaaattagga accgtacacc gaacctcggt ttccgctttc
     3181 ctattttctt cttcgatggt tcctcgctct tctggctaag gtctttgaaa aatcttatga
     3241 gttaacttta acacacgtat gcatacaatg caatacccac atacaggtaa ttaaatttct
     3301 tcccagttcc tacattacca caaagttatt gaaaaatcca gtctttttat aaaactttga
     3361 catttttttc acaaaatctt catatttttt ccataactga aaggacgcca gaagttaatt
     3421 tttcctaagc aagcaattgt tagttgcaag ggtaaaatta acttctgacg tcttctcttc
     3481 aaaatcttaa aattaaatat taaagattct taactgtcgc gatgtcgatc atcgtcatct
     3541 gatcatttgc tgtctcaagg ctgagtgcca gcgcatttgc cgtatccatg gatgtcaggc
     3601 agtgaacgcc tgtctcaatg gcatttcggc gaatgaggaa tccgtctctg gatttatcac
     3661 gtccctgtgt tggagtatcg ataacaaggt caatcttgtg tccgaggatc agatccataa
     3721 catttggtga ttcctgagaa attttattta cgcgtcgggc atttacaccg tgatcctgca
     3781 gatattttgc agtgcttctt gtggcataaa tcgtatatcc cagtgcttca aaacgttttg
     3841 caacgccaac tgattcttct ttatccgaat ctttgacggt catgatcatc cgtttgtact
     3901 tcggaagctg gataccagca ccgataaatg ctttgtacag tgcttcgttg aaattcttgg
     3961 caataccaag acactcgccg gtagatttca tttccggtcc aagactgatc tccgctccac
     4021 gcagtttctc aaaggagaat accggcatct tgattgcaat ataatctgcc tccggtgcca
     4081 gtcccggctt gtatcccatt cctttgattg tctcaccaag gatcactttg gttgccagat
     4141 ctacgatcgg gatacctgtt actttgctga tatacggtac ggttctggaa gaacgcgggt
     4201 ttacttcgat aacgtatact tcctcgttca ttgcaataaa ctggatattg atcagtccta
     4261 caacatgaag tgctcttgcc agacgttttg tatattctac aatcgtctct tttacatgat
     4321 tgctgatcgt cggtgccggg tatacagaaa tactgtctcc ggaatgtaca ccggtacgct
     4381 cgatatgttc cataataccc gggatcagga tatctgtacc atcgcatacc gcatcaacct
     4441 caatttcttt acccatcagg tatttatcga tcaagattgg atgatcctgt gcgatctgat
     4501 taatggtatc aataaattct acgatttcat catcattgaa ggcaatatgc atgccctgtc
     4561 cgccaagtac ataagaagga cgaacaagca ccggataacc tatgcggttt gctgccactt
     4621 ttgcttcctg agccgtataa acagtatcac ctgctgctct cggaatattc gtcttctcca
     4681 ggatttcatc aaaaagttca cggtcttcgg ctgcatcaac atcctctgct tttgtaccaa
     4741 gaatcggcac acccatcttc atcaggcttt ccgtcaactt gatcgcagtc tgtccaccga
     4801 actgtacaac tgctccatcc ggtttctcga tgtttacaac attctcaaca tcttccggtg
     4861 tcagtggttc gaaatacagc ttgtctgcaa tgtcaaagtc agtggaaacc gtctcaggat
     4921 tgttattaat aataatggtt tcatatccgg ctttggaaaa tgcccatgta caatgaaccg
     4981 aacagaaatc gaactcgata ccctgtccga tacggatcgg accagatcca agtaccagca
     5041 cttttttctt ctttgctgtt ccatctgcct cattttcacc gtcaaaacag gaataataat
     5101 atggtgtgct tgccgcaaac tcagcagcac aagtatcaac catcttgaaa gaagctgtga
     5161 taccgttctc ataacgcata tttttgatgt agtcttcgtc tttacctgtt aactgagcaa
     5221 tcactttatc cgggaactca atacgttttg cttcacgcag cagatcaaca gtcagtgctt
     5281 cgctgcgcag acgaccttcc atttcaacca ggattgcaat tttatcaatg aaccacttgt
     5341 caatctttgt gatttcatgg atggtgtcat aggaaacacc acgacggcat gcctctgcaa
     5401 taacccagat tcttctgtca tctaccactt tcagacgctc gatcagttta tcataagaaa
     5461 gtgtcagata ttcatcagaa acaagactgt ccacatgctg ttcaagggaa cggatggctt
     5521 tcatcagcgc accttcgaag tttgtacaga tactcataac ctcaccggtt gctttcatct
     5581 gtgtagtcag tgtacgtttt gcagtgataa atttatcaaa cggcagacgc gggatcttta
     5641 caacgcaata atccaacatc ggctcgaaac ttacataagt ttttcctgta atggcatttt
     5701 tgatttcatc cagtgtatag ccaagtgcga tctttgcggc aacttttgca atcggatatc
     5761 cggttgcctt ggaagccagg gcggaagaac ggcttacacg cgggttaacc tcgatgacac
     5821 agtattcaaa ggaatccgga ttcaacgcat actgtacatt acatccaccg gtgatgttca
     5881 gctcactgat aatatttaac gcagaagtac gcagcatctg gtattctttg tcacccaatg
     5941 tctgggaagg tgctactacg atagaatcac cggtatgcac accaaccggg tcgatattct
     6001 ccatattaca tacggtaata cagtttccgt tggcatcacg cattacttcg tactcgattt
     6061 ctttccatcc ggcgatgcag cgctcaacca gaacttctcc gacacggctc agacgcagac
     6121 cattactcag gatttcaact aattcctctt cattatgagc aataccaccg ccgcttccgc
     6181 ctaaagtgaa agccggacgc agtacaaccg gataaccgat ggtatttgta aatttaatac
     6241 catcctctac cgtatttaca accagagaag ctgcacacgg ctcgccgatt ttttccatgg
     6301 tatctttgaa cgcctgacga tcctccgcac ggaaaatagt ctcagctgtt gtaccaatga
     6361 gttttacacc gttttcttct aaaaatccgg attctgccag ctccatacca aggttcagac
     6421 cagcctgtcc acccagagtc ggaagtacgc tgtccggttt ttcttttaaa ataatctgtt
     6481 ttaacacatc aacggtcaac ggctcgatat aaacctgatc cgcgatctgt ttatctgtca
     6541 tgatggttgc cgggttggag tttaccaggc aaacttcaac accttcctct ttcagggaac
     6601 ggcatgcctg tgtacctgca taatcaaact cagcagcctg tccgataacg atcggaccgg
     6661 aaccgattac taatactttt ttgatatctg atctctttgg cattatttct gtcctcccat
     6721 catttcaata aacttgtcaa acaggtatcc ggaatcctgt ggcccagggc atgcttccgg
     6781 atggaactgt acagtaaaga tattctttcc tgtatacttg agtccttcgt tggttccgtc
     6841 atttacattt gtaaacgcag gaactgctac tgcttgatcc agactgtctg catccaccgc
     6901 gtatccatgg ttctgggatg aaatgtatac acgacctgtc tccagatctt ttaccggatg
     6961 attgccacct ctatggccat atttgagttt ataagtatct gcgccggtag ctaatgccat
     7021 cagctggtgt cctaagcaga tagcaaaaat cggtacttct gaatcataaa gttttttcac
     7081 ttctttgata atatctgtgc aggcttttgg atctccaggg ccgttagaaa gcataattcc
     7141 gtccggatca gaagaaagaa tctcctcagc cgttgtgtgt gccggataaa tcgtaacttc
     7201 acagccacgt ttgtgcaggg actgtgcaat attgttcttt gcgccaaagt ccagcagtgc
     7261 tactttatag ccatctgctt tcagcacttt tttctcgctg caagtcacct tatccactac
     7321 atttcctgta ttgtatacat gaagctgagg caaaatttca tccagtttgt aattttcatc
     7381 tgtggtgatc ataccattca tagttccttt ttcacgcaga atttttgtca acgctcttgt
     7441 atcaattcct gcgattcccg gaatatcatg ttctttcaaa aaatcctgaa tggttccctg
     7501 gcaacggaag ttacttggaa ttctggataa ctctcttacg atatatccgt ccggccatgg
     7561 ctgtgcagac tccatatccg gtgtaactcc ataatttcca atcagcggat acgtcattac
     7621 aactgcctgt cccgcatagg atggatctgt caaaacctcc agataaccag tcatggaagt
     7681 attgaagacg atctcactga tcacgctctt tgtcgaacca atgcttgttc cggtaaatac
     7741 tgtaccgtct tccagaatca gaaatgcttt catttattcg cccgtccttt ctcttttcta
     7801 caatatacac tttgcatcca aaaatgttct cacatttttg ctgcgagatg cacgtcatgc
     7861 agcgcatgat aaatatctct gtccatctct gtaatcttac tacattttaa catgtatttg
     7921 ctggcttgtt gcaaaaaaaa agagggaatt ttctcttttt ctgtatattt atacattatt
     7981 tatgcataat attcattttt ctgccatata tacaaattgt aggtatttta tcatagtttt
     8041 ttcctttttt caacacttac tttcatgatt tctcacttaa gcaacagcgg caaggcccga
     8101 cgtcatcgcc agaccttgcc gcttcttaat tactcaattt ttgtttttcc acccatatat
     8161 ggctgtaatg ctttcggaat attaacagtt ccatccgcat ttaagttatt ctccagaaat
     8221 gcgatcaaca ttcttggcgg agcaactacg gtattattca atgtatgtgc cagatatttc
     8281 ttaccatcag caccttttac acggattttc agtcgtcttg cctgagcatc accaagattt
     8341 gaacagcttc ctacttcgaa atatttcttc tgacgcggag accatgcctc aacatcaaca
     8401 gatttgacct tcaggtcagc aaggtcaccg gaacagcact ctaacgtacg aaccggaata
     8461 tcaagactgc ggaacagatc taccgtattt tgccataatt tctcatacca catcatagaa
     8521 tcttctggtt tacatacaac gatcatttcc tgtttttcaa actgatggat acggtacaca
     8581 cctctctcct cgataccatg agctcctttt tctttacgga aacatggaga atagctggtc
     8641 agagtctttg gcaactgctc ctcatcgatc atcgtatcaa taaagcttcc gatcatggaa
     8701 tgctcggaag taccgatcag atacagatcc tcgccttcaa tcttgtacat catagcatcc
     8761 atctcatcaa aactcataac accggtaaca acattacttc tgatcatgta tggcggaatg
     8821 cagtatgtga atccacggtc aatcataaag tcacgggcat aagccagaac tgctgagtgc
     8881 aaacgggcaa tatccccttt cagataatag aaaccgtttc cggctacttt tcttgcactg
     8941 tcaagatcaa taccatcaaa tttctccatg atttctgtgt gatacggaat ctcgaaatcc
     9001 ggaacaaccg gctcaccgaa acgctcaact tctacgttct cactgtcatc ttttccaatc
     9061 ggaacagacg gatcaatgat atttgggatg gtcatcatga tttttttgat tttctcctga
     9121 agctcgcctt cctgtgcctc aagttctgtc agacgctctg catctttggc aacctgctct
     9181 tttaatgcca tagcctcttc tttttttccc tgtcccatca gagcaccaat ctgtttggag
     9241 atacggtttc tgttggcacg cagatcatcc gcttcctgct gaactgttcg ggatgatgca
     9301 tctaattcga ttacttcatc caccagacca agtttgtgat cctgaaattt atttttgata
     9361 ttctgtttta caatatccgg gttttctctt aaaaacttaa tgtcaatcat agcttcctcc
     9421 tgaggaaatt ttattctttc aaaagtatac actgattcac agcaatattc aagccttgtt
     9481 ccttgtgttc tggataaatt ttgtatcgaa ttttgtatcg gtaaaccttt taatcacaca
     9541 agcaagatct attctcggcg taacgcatca attggtttca gatttgctgc tttataagat
     9601 ggcagtaatc cgaaaataat tccaattccc atagaaaatc caactgcaat gattgccgcc
     9661 gggatactaa taaccacagg catctcacta actttagaaa tcacctccgc gagcacgatt
     9721 cctgcaatta caccgatgat accaccaagg ctggtcaata cggctgcctc tgtcagaaac
     9781 tgaccgagaa tatggctctt ctttgctccg atcgcttttt tcagcccaat ttcctgtgtg
     9841 cgttctgtca cagatactaa catgatattc ataacaccga taccgccgac cagaagcgaa
     9901 atacctgcaa tccagatcag catgcggttt gtggactggc tcagttcctg aatatcctgt
     9961 gcctgtttta acaaatcctg gcctttatat tggattgtac tatcagaaac actgagattt
    10021 gcgttcagga tatctgccac cgcctgacct gcagatgcca tggaatctgt atctgttgct
    10081 tttaaaacca cactctgtgg ttcatcatac tgaaatacaa tcggccatgt ggcagatgga
    10141 ataaacactc tgccactgct atcctgcatg taagtataat agtcatccat agaattgatc
    10201 actggttcaa aaccatcttt tttatctgca attccaacta caatatacgg ttctccctga
    10261 atctcgatgg tctttcctat cgcatcggct ccctgaaata acgaagatgc actatcccga
    10321 tctaaaattg ccacttttct gtatttcgca taatcattac tgtcaaaccc acggccctcc
    10381 ttaatggtat aactgcaggt atccagataa tttgcatcaa cgcccatgac ataaccaccg
    10441 gaaagagatg tattgccata acataccgta tcataaccct gacggctggt atagcgggat
    10501 gcttcctcca caccatccac tgccagaatc tgctgcatag tatcatcact gatcaccgga
    10561 acaccatccg gaattccgtt ataatccatc tcgtaagtcc attcatcctg ataaagttga
    10621 actgtcactg cattatttcc ggcacctacc agattctgtt tgatctgctc atttgttccc
    10681 tgaattgtgg aaacaattgc aataattgca ccaataccga taatgatgcc aagcatcgtc
    10741 agaaaggaac gcattttatg agaccagatg ccctgaaagg acagtctaat attttctaac
    10801 atttcacgca cctcccctta ctaatatgag ccatcggaat ccaccgcacg gacaccctct
    10861 tttgccgttt ttccatatgg aaaggcaatg cggtcatctt cactcaagcc ggctttaatt
    10921 tcaattgtat ctccgtaaat gattcttcct gttttcacat actgtttcac cagacgatca
    10981 ttttcatctg ctttcagtac gtaagacttt ccattttccg tacggacata tcctttaaaa
    11041 atataaagag aacttcctgt ttcatcatcg gaaactgtca tggtcagatc cacatattcg
    11101 ccatttcgaa atcctgacgt atcttcaata taagcgacaa atgggtagta agacacatta
    11161 ttattgcctt ctccataaga agaaacatcc gtggaaggat agtttttaat ctcggtaatc
    11221 tctgcctcgc agcttgatcc gctttcccac gaagatacac tgaccatctg ccccggtttt
    11281 accttatcca gaagtaattc gctgattcct cctgtcacat atagaccttc cgaacctgtc
    11341 acctccataa atggcgtacc gtcatttggc agattatctt tatcctgcaa attttttact
    11401 atgccggtaa ccgtagcata tatcattcca tcggaactct tcgctttcag tttttctact
    11461 tccagttccg cttttcgctt attcaggtcc agctccttga tttttttctc ctgctctgcg
    11521 atcatatcat ttaattccgc ctgggtgtaa ccgccttcat ctgatattct gtcattgaca
    11581 acactcgaat catcctctgc ctctgatgca tcatttgaaa tctggctgtg atcatatacg
    11641 gaccattttg tatttccatc aggcacaacg atctgtgcac cgtccacttc ccatgcggtc
    11701 acaagttctc cggaaacttc attattttcc cgaatctcga atacagcata tgttttttct
    11761 tctgccagct ggcttaaaaa gtctcccgtc acataagctg attctgtaca caggtaacga
    11821 taaggattct cttcgctgcc atctgcgctg ttctgattat atggaacggc agtcccggaa
    11881 atatagttgt atgcatttcc tgccatctcc tgcacatgtg gtatatcagg ttctggcgtc
    11941 accggattgg ctggctccac atatggtttc gtatttttta atttttttaa atcattctga
    12001 gcaatagtaa tctgattatt cagattttct acttccagct gttttccctg taaattcagg
    12061 gaagctactg tcgtatcaag tgccagcagt ttatcacctt tctgcacctg ctgtccttcc
    12121 tttacataca cctctttgat ttcatccgta ttcgtaattt ccacagactg agaataatca
    12181 ttcgtaatca ttccggagct attaacatcg tctccccaat atccactatt taaatctgcc
    12241 acagacatca cttccgctgt cattttggcg cgctgtacat agacaccggt tccgatgctg
    12301 cctcctgcaa tagctgcaac aatggcgatc acaagaacac gtttcatgac tttcctattt
    12361 ttcattctgc cgcctcctct atctcaccat caatgatgtg gatcacacgt tttgcataag
    12421 acgcaatctt tgcatcatgc gtgatcatga caatggtcac accttcttca ttcagacggt
    12481 caaaaagctc catgatctgt ctgccggact tggaatccaa tgctcccgta ggctcatcag
    12541 ccagtaaaat cttcggattg ttcaccatag cacgggcaat ggctacacgc tgtttctgac
    12601 cgccggacag ctgcgttggt ttgaactcca cacgatctgc cagccccaca cgatccagcg
    12661 cagcagccgc acgtttttcc cgatccggct tctttactcc cgcataaatc agaggcaatg
    12721 ctacattttc cagtgcgctc tctctaggca gcaaatgaaa actctgaaac acaaacccga
    12781 tactgttcag tctgacatct gcaagttccc ggtctttgca ttgtaaaaca tcctgccccg
    12841 ccagttcata gctgccactg gtaggcaggt ccaggcatcc gatgatattc attaatgtcg
    12901 tttttccg
//
