LOCUS       NZ_CP085975.1          24645 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP085975.1 Parabacteroides johnsonii strain FDAARGOS_1580
            chromosome, complete genome.
ACCESSION   NZ_CP085975
VERSION     NZ_CP085975.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:12:46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2485746
            Orig. end    :: 2510391
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24645
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2495746:2500391]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14645
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24645
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24645
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="2"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(593..3370)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2068"
                     /sec_met_domain="Peripla_BP_1 (E-value: 2.2e-06, bitscore:
                     25.2, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFLRTFAETCKQNRMKPALTYYALLVLLLAFCFSCKTDSEKKKY
                     VIGVSQCTLEGSWRKSMLLDMKVQASEYPGVSLLVEDAADSSLLQVEQIRSLIKRKVDL
                     LIISANESEPVTPIAIEAYRAGIPTILVDRKISSDEYTTYIGGNNYEIGRQAAFFVNRQ
                     VKEKYPTVLEVWGLSGSSPAQDRHRGFMDVLNSRTKVKEIYGKWKPETVEKEIAKMDSL
                     EEVDVVFAHNDVMAMAARRAIEKKHPGLADQIRFVGIDAVSGRGSGLEAVMHGELAASI
                     LYPTGGSLAIRVAMQILNGEDVSRQYLLSSALIDKNNAGTLFIQSEQVVDYQHQIELQR
                     ENLESMLSKYTFLQSSVSIILLLMGLLLLSALYVIHVNRTVKRKNRELKRTNLQVQQQK
                     EELAEANRYIEKSTAQKLQFFTNITHEIKTPLTLILGPLGKLSKEAPEGSSLADDIRII
                     RKNAERLKRVVDQLLDFRKVESNKMNMRVGEVDLVAFVAEVKSCFDTMAAAKQIHFTFE
                     HDCPSVSIWVDRDKMEKILANLLSNAFKFTLDGGTITVRLKDKGDQVELSVEDNGKGIP
                     LENIASVFDRFFTGDQNYVTGTGIGLHLTREFVHMHKGTIRVESVPHKSTVFTVVLLKG
                     KSHFDESCTFDLSVTELSSGVANLNTDELQEALDRTYDYTVLVVEDDPDIQGYLQAELK
                     QNFHVLVADNGVKALEVLMSEEVSVVVSDVMMPEMNGFDLCRKIKSDIVLSHLPVMLLT
                     ALSDDKQQMYGAASGADAYIQKPFNIEVVKLRIIKLLEDRAQLREAYARDASSPAVSVK
                     EEKAESMDDLFMNRFLKLIEESYADPDFSIEKGSEKLGLSRVHLYRKVKELAGVTPTDF
                     LRNYRLKKAAALLRRKAGNVNEVAYATGFGSPAYFSKCFKAVYNITPTEYLEKE"
     CDS             3422..3889
                     /locus_tag="ctg1_2069"
                     /transl_table=11
                     /translation="MKIINEALLDETTGRAKQSPRLRMNYNFHERLDDPVNRLLNALEP
                     GTYLRPHRHLNPAKDEIFLLLRGRIAVFLFDNKGEITETQILDPKEGAYGAEIKAGTWH
                     GLLVLESGSVIYEIKEGPFAPLAPENFAPWSPAPEDTEGVEKYMELLGKAI"
     CDS             complement(4399..6246)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2070"
                     /sec_met_domain="Peptidase_U32 (E-value: 2.7e-72, bitscore:
                     240.5, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTKSRPIELLSPAKDLNCGMEAINHGADAVYIGAPKFGARAAAG
                     NSLEDIRELCDYAHLYGARIYVTLNTILKEEELEEAERMIWDLWHAGTDALIVQDMGIT
                     RLNLPPIPLHASTQTDNRTPEKVRFLQAAGFTQVVLARELSLNEIRRIAEATTVPLEVF
                     VHGALCVSYSGQCYLSAALSGRSANRGECAQYCRLPYTMVDATGAEIVTHKHLLSLKDM
                     NRSDQLEALLDAGVSSLKIEGRLKDVDYVKNITAYYRKKLDAVLSRRPEYRRASAGRST
                     YTFEPVAEKSFNRGFTPFLLEGRTADITAFNTPKSLGEPVGTVKEIKGNSFTVAGLKQL
                     NNGDGLVFFNRKGELEGFRVNRVEANRVFPLDMPQLAPKTPLYRNFDQVFDKLLAKPSA
                     ERRLSVKIEFLDNPFGFTLCMEDETGARIMLAEPFAKELARREQQDNIRTQLSKLGNTP
                     FEASEVVVGLSENWFVPSSLLADMRRRGVEKLLEVRRARYPRETVKRVRLSEPIPFPER
                     SLTYLGNVANGKARSFYQDHGVEQVDPAFELSPRKDVPLMFTKHCLRYSMGWCPTYQKN
                     KSPYKEPYYLLYKDTCLRLQFDCKHCQMLVFEHTRLAGK"
     CDS             complement(6269..7201)
                     /locus_tag="ctg1_2071"
                     /transl_table=11
                     /translation="MPLNLQKNLPAVELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMP
                     LKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNTPIEHMQEFYKDFDEMQDDFYDGMI
                     ITGAPVEQMPFEEVNYWEEVTEIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDLPAK
                     MFGVFRHTLREPYVPIFRGFDDEFYVPHSRHTEIRREDVMKVPDLTLLSESEESGVYMA
                     MARGGREFFITGHSEYSPYTLNDEYMRDVNKGLPIAVPRNYYRNNNPALGPVVRWRGHA
                     NLLFTNWLNYYVYQETPFRIEDISKLGDL"
     CDS             7451..9856
                     /locus_tag="ctg1_2072"
                     /transl_table=11
                     /translation="MKIRAIATLLFILFSISAFGQGRAKISGYIRDADGNPLDLVNIRV
                     KNTLNGTMSNEKGHYSLSVATGDSVTLIYSCLGYNKAERILPLVTKDMRLNVQMNYTSL
                     ELGEVVATAIRKQTTTLETLNADRVKLLPDPAGGSIESLVVTFAGVTSNNELSSQYSVR
                     GGSYDENIVYVNGLEVFRPLLIRSGQQEGLSFINPDMTEAVNFSAGGFEARYGDKMSSV
                     LDITYKKPKGFEGSASASLLGANAYVGSSSGKFTQVTGFRYKTGRSLLKTTDTDAEYDP
                     NFIDLQTYMTYQFAPKWEINFLGNLAINNYKFIPHTRETSFGTATNAKKFKVFMSGQER
                     DKFETLFGALTLKHNLNENTELGLQASAFTSKEEEGYDIAGDYWLGDAAEEGGGEIENL
                     SIARYNEHARNRLHSNIMNVGHYGIARMKNNTLKWGATVQLEKINDKISEWEKRDSAGY
                     SLPQGGGNVNVIANLFSDNELESTRISGYLQDVFKFRTKQGLFTLVGGVRGSYWSYNKE
                     FIFSPRASIGFIPNFDQNLTFRLASGLYYQSPFYKELRTTVQDEHGNSIIQLNKNLKSQ
                     RSIHVIAGGDYTFRASGRNFKVSADMYYKKLDNLNPYTVDNVKIRYYGENCAEGHAMGL
                     DVKFFGEFVPGTDSWISFSLMKAEQSIRGSEYVPMPNSQGYNVSLFFQDYFPGYKRVKL
                     NLKGVLSGGLPVTAPRTGYEDGYFRTPTYKRVDLGFSYQLAGGTDAIMDRGFFRNLKNI
                     WLGLDIFNLFDIKNTSSYYWITNIDNHQYAIPNYLTGRQLNVRLIVDF"
     CDS             10001..10408
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2073"
                     /sec_met_domain="Glyoxalase_4 (E-value: 6.6e-25, bitscore:
                     85.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEEVLGLKCYNIEEVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAESKGVKLIDK
                     APRGGAEGLDIAFLHPKSTCSVLTELCMPGK"
     CDS             10528..12081
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2074"
                     /sec_met_domain="CT_Btheta (E-value: 4.7e-290, bitscore:
                     960.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALRETARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIYAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLISFLPQNNLEETPLIECKDPIDRLDDNLNDIIPDNPN
                     QAYDMYDVIGTIIDNGEFLEVHADYAKNIIVGFARFNGQTVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAASEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             12103..12990
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2075"
                     /sec_met_domain="OAD_gamma (E-value: 8.8e-12, bitscore:
                     43.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNKKIGVLLLFALLVSFGAKAQLATSMRINEVLVINEDNFVDDY
                     GKRHGWIELYNSSAGTVNIAGCFLTDDKNNPKKYPIPKGDVLTQIPPGQHVLFWADNEP
                     DRGTFHVSFSLDPTKENYVALYNADGKTLIDEVTIPAGQVADVSFGRIIDGKEEWAQLT
                     KVTPSTNNLTLDSNEKIDNFKENDSWGIGMTITAMAVVFLGLFLLYVIFKQIGKISIAV
                     SKRNAKKAAGTTPIADNAGQESGEIFAAIGAALYEISDDNHDIENTVLTIRKVQRAYSP
                     WSSKIYGLREMPKK"
     CDS             13013..13444
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 64.7; E-value:
                     1.7e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2076"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.1e-18, bitscore:
                     64.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHINSIVEDVAEVEVNGTPYQVKMEKPAKKQ
                     MVTLKRPAQAPTTASGEPVISRPAASTTKGAVKTPLPGVILQIKCNVGDTVKRGQTLLV
                     LEAMKMENNINADRDGKIIEIKVNKGDSVLEGADLVVIG"
     CDS             13449..14645
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2077"
                     /sec_met_domain="OAD_beta (E-value: 8.6e-151, bitscore:
                     499.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGSVLLQAAGVAHESFLQFLGKNLELFLTYTGVYNATPGHLIMI
                     LIGLLFIFLAIKYEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTS
                     GWYPPLIFLGIGAMTDFSALISNPKLLLIGAAAQFGIFGAYIIALQMGFEPNQAGAIGI
                     IGGADGPTAIFLSSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERLIRMKPP
                     RAVSSTEKIVFPIVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDT
                     ITILLGITVGASTQATQFLTIDSVKIFGLGALSFVIATCAGVLFVKVFNLVLKEGNKIN
                     PLIGNAGVSAVPDSARISQIVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(14966..17428)
                     /locus_tag="ctg1_2078"
                     /transl_table=11
                     /translation="MKKDKVTMFAEESYNDLDDNIGIVMPILTDCDVDEDFTEGMEKVG
                     EELPILPLRNMVLFPGVAMPVMIGRPKSMRLIKEAAHKKSLIGVVCQKDMNTEDPKMED
                     LYTTGVVADIVRVLEMPDGTTTVILQGKKRFQLEELSAYDPYLTGKIKLLEDVMPDKSD
                     REFEALVSTIKDLTIKMLGAASEPPRDLIFSIRNNKNILYLINFSCCNVPNGSSEKQDL
                     LLIGNLKDRAYRLLFILNREYQLVELKTSIQMKTHEDINQQQKEYFLQQQIKTIQEELG
                     GNINELEIKELREKAAKKKWSPSVAETFEKEVRKLERLHPQSPDFSIQTQYVQTIINLP
                     WNEYSKDNFNLAHAQKVLDRDHYGLEKVKERIIEHLAVLKLKGDMKSPIICLYGPPGVG
                     KTSLGKSVAEALHRKYVRVSLGGLHDEAEIRGHRRTYIGAMSGRIIQNLQKAGTSNPVF
                     ILDEIDKVTNDFKGDPASALLEVLDPEQNNAFHDNYLDIDYDLSKVMFIATANNLNTIS
                     QPLLDRMELIEVSGYIMEEKVEIAARHLVPKQLEIHGLSKGKVKFPKKTLQAIIESYTR
                     ESGVRELDKKIAKIMRKLARKLASDEELPAQIRPEDLHDYLGAVEYTRDKYQGNDYAGV
                     VTGLAWTAVGGEILFVESSLSKGKGSKLTLTGNLGDVMKESAMLALEYIHSHAGLFGID
                     EGMFENWNVHIHVPEGAIPKDGPSAGITMVTSLVSAFTQRKVRSNLAMTGEITLRGKVL
                     PVGGIKEKILAAKRAGIKELILCQENKKDIEEIKPDYLKGLTFHYVDDIRQVVDLALLK
                     EKVANPLF"
     CDS             17624..18340
                     /locus_tag="ctg1_2079"
                     /transl_table=11
                     /translation="MSNPFFQFKQFTIRHDKCAMKVGTDGVLLGAWAGIESCNRILDIG
                     TGTGLIAMMLAQRSKAVIDAIDIDAEACLQAQENAESSPFAERIKIQHSALSDFAQTDT
                     GLYDLIVSNPPYFVDSLKCPDQKRNTARHTDTLTLEDLLQDSRKLLAPQGRIALILPYD
                     QKERLTDCIRTQNLFLSKETSVIPVPGAEPKRLLAELTAEPPVFPTFSSQLTIEIARHQ
                     YTDEYVSLTKDFYLKM"
     CDS             complement(18325..19296)
                     /locus_tag="ctg1_2080"
                     /transl_table=11
                     /translation="MEGQTINIQAIINPISGVGSKRKIPKMIETAFAGGNCCVEISFTE
                     YPGHASELTRQALDKGANCVIAVGGDGTVNEIARAMLHSDAVLGIIPKGSGNGLARELH
                     IPMDVRRAIDLIVKGHVSTIDCCKANGRIFFCTCGVGFDAAVSQKFAGEKRRGSLTYIK
                     NTVEEYLSYQPEPYELLIDSQTVKEKAFLVACGNASQYGNNAFIAPHANIQDGKMDITI
                     LSPFGPLDIAPLAIQLFTKQIDRNSKIKTFKGKEVTIIRQNPGVMHLDGEPIMADSRIE
                     ISVLPKSLNVLTPETVSFTEEVQNLFGEVTRFFDKKLPYIFR"
     CDS             19491..20678
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2081"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7.6e-61, bitscore:
                     204.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLLQEKLSKYDAPQRAMAAGIYPYFRMIESDQDTEVMISGKKVL
                     MFGSNAYLGLTNHPKVKEAAIDAIKKYGTGCAGSRFLNGTLDLHIQLEKRLAEFVGKED
                     AIVYSTGFQVNLGVVSCLTGREDYIIWDELDHASIIEGHRLSFSTKLKYKHNDMESLEK
                     QLQKCEPDKVKLIVIDGVFSMEGDIAKLPEIVALAKKYNASVMVDEAHGLGVLGDHGRG
                     TCNHFGVTDDVDLIMGTFSKSLASIGGFIASDKETINYLRHNSRSYIFSASNTPAATAA
                     AGAALDIMLSEPERIEHLWKLTHYALDGFRNMGCEIGHTSTPIIPLFIRDNDLTFLIVK
                     ELFEAGIFVNPVVSPAVAPEDTLIRFSLMATHTIEQLDYALEAIHKVFKSHGLVK"
     CDS             20832..22283
                     /locus_tag="ctg1_2082"
                     /transl_table=11
                     /translation="MDFKLNTGSCCMGKKGCSKIQNNKLNTYDWLCDVPDAANATDYVE
                     VQFKNTRKGYYLNSSKIPLEKGDLVAVEASPGHDIGTVTLTGKLVLLQMKKNNVRTGEG
                     NEPKKVYRKAKPTDIEKYEEAKAKEHATMIRSRQIAADLGLNMKIGDVEYQGDGNKAIF
                     YYIADERVDFRQLIKVLAEAFRVRIEMKQIGARQEAGRIGGIGPCGRELCCSSWMTSFV
                     SVATGAARYQDISMNPQKLAGQCAKLKCCINYEVDAYVEAQKRLPSREVVLETKDNTYY
                     HFKTDIFKREITYSTDKSFAANLVTISANRAFDVINMNKKGMKPVTLEADTKPQPPKRD
                     AQDILGQDSVTRFDASLKKKKKKRNGNGNKENLPKETVANTGSEGNSKPTNGEKANGNN
                     GNENKNGKGNGNRNGNRNRNNGNRDNNRERENRENNRDNNRNRPRPNRVNNDKQPNNDK
                     PQQQAKPATKPDSKPENKPDTKPEA"
     CDS             22339..22734
                     /locus_tag="ctg1_2083"
                     /transl_table=11
                     /translation="LYDQYQAINNITWEKDKEYYFTFEVKDISVPYDLTLEVRNNNLYP
                     YQNLWLFCSEEQPIGPLRRDTIECILADEFGKWHGHGISLYQSSFPIHSQYKFPYAGQY
                     TFSFRQGMRDDALKGIQEIGFSVRPSH"
     CDS             complement(22773..24257)
                     /locus_tag="ctg1_2084"
                     /transl_table=11
                     /translation="MRLYRQTFYLYRIVSYRKTEIWKTVDWLTIILYVVLVVAGWFSIC
                     GASYEFDNVGLFDPSGRPGSQLMWMGLSVGLIFVILMLESEFFDVFAYLIYAGVIVLLI
                     ATIFLAPNIKGSHSWLVLGPVRLQPAEFAKFATALAVAKLMNTYGFKLTVPKNFILVLS
                     LIFLPMICILLQQETGSALVYLAFFLMLYREGMSGYILLSGVCAVVFFVTSMKFSDVTA
                     GATAVGELLVSSLILLITVILIQIEKKDTRAIQAILGAVGIACLGGYAASFFMPVDYSL
                     ISIGLVLLVVCYLIFLSIRNWVWHYVLIAVFALGSLAFMYSVDYVFTDILEPHQQIRIK
                     VSLGLEDDPSGAGYNVNQSKIAIGSGGLTGKGFLNGTQTKLKYVPEQDTDFIFCTVGEE
                     QGFIGASIVLLLFGFLILRLIVLAERQSSTFNRVYGYSVASIFFFHLAINIGMVTGLTP
                     VIGIPLPFFSYGGSSLWGFTILLFIFLRLDASRRER"
ORIGIN
        1 ctctctcgac tgcgcggaac gctgtcctaa agtaccgaag caaatggcat ccgcccgttc
       61 agccagatcg atcgcattcg acgtcggaga aagatgatcc caggctacac gttcgttgat
      121 aatataatca gggacaccat tctgcaaagt aacctgtacc gttccggtcg gataagggac
      181 tttctcgatc agataccgga tcgaattatt atccagctcg ccgagtattt catgtcccag
      241 ctcgtcgtct cccacggcgc tgatggcata tccttccgca cccaaccgtg aagcatggta
      301 gacgaaatta ataggagcac cgcctgcttt ctttcctgtt ggcagcatgt cccacaagag
      361 ttctcctatg cctactacga ccggtttctt attgttgctt tgcatttgtt tcattatagt
      421 ttatttgaca aggataattt cgtttttcac gatgcaaaga tagataccgg gggcggatgc
      481 gacgataaca aatgctacag gattgataac gtttgttaca taatgcactt attttcaagt
      541 tacatacaca gatgttacac aaatgtaacg agcgttatca aagagaagga tattattctt
      601 tttccagata ctccgtcgga gtaatattgt aaacggcctt aaagcatttc gagaaataag
      661 caggcgaacc gaagcctgtc gcataagcca cctcattcac atttccggct ttccgacgga
      721 gcagggcggc ggctttcttc aaacgatagt tacgcaggaa atcggtcggc gtcactccgg
      781 caagctcctt cactttccgg taaaggtgta cacgcgacaa gcccaacttt tcactgcctt
      841 tctcgatgct gaaatccgga tcggcatatg actcttcaat cagtttcaag aaacgattca
      901 taaaaagatc gtccatgctt tccgcttttt cctccttcac ggagacagca ggcgaggaag
      961 catcgcgagc ataagcctca cgcaactggg cgcgatcctc cagcagcttg atgatacgca
     1021 atttcacgac ttctatgtta aaaggcttct ggatatacgc atccgcaccg ctggcagctc
     1081 cgtacatctg ctgcttgtcg tcggacaagg cggtcaacag cataaccgga agatggctca
     1141 ggacaatatc cgacttgatc ttgcggcaaa gatcgaaacc gttcatttcc ggcatcatca
     1201 catcgctgac aaccaccgaa acctcttcgc tcatcagcac ctccaaagcc ttcacgccgt
     1261 tatcggcaac caacacatgg aagttctgtt ttaattccgc ctgcaagtaa ccctgtatat
     1321 caggatcgtc ttccacgacc aagaccgtat aatcgtaggt gcggtccaaa gcctcctgca
     1381 attcgtccgt gttcagattg gcgacaccac tggaaagctc ggttacggaa agatcgaacg
     1441 tacaggattc gtcaaaatga gatttacctt tcaagaggac aaccgtaaag acggtacttt
     1501 tatgcggaac actctccacc cggatcgtac ctttgtgcat atggacgaac tcacgcgtca
     1561 gatgcaggcc gatccccgtc cccgtcacat agttctggtc gccggtaaag aagcggtcaa
     1621 aaacggaagc aatgttttcc aacggaatac ctttgccatt atcttcgaca gaaagttcga
     1681 cctgatcgcc cttatccttc aggcgaaccg tgatcgtacc tccgtccagc gtgaacttga
     1741 atgcgttaga caaaagattg gccagaatct tctccatctt gtccctgtcc acccatatac
     1801 tgacagaagg acagtcatgt tcgaacgtga aatgtatctg cttggcggca gccatcgtat
     1861 cgaaacaaga cttcacttcc gccacaaaag cgactaaatc cacctcgccg acccgcatat
     1921 tcattttatt gctctccacc ttgcggaaat cgagtaactg gtccactacc ctcttcaacc
     1981 tctccgcatt tttccggata atgcggatat cgtcggctaa cgaagaacct tcgggcgcct
     2041 ccttcgacag cttgccgagc ggaccgagaa taagcgtcag cggtgtcttg atctcatgcg
     2101 tgatattggt aaagaattga agtttctgag ccgtcgactt ctctatataa cgatttgcct
     2161 cggccagttc ttctttttgc tgctgtacct gcaagttcgt gcgtttcagc tcacggttct
     2221 tccgcttcac cgtccggttc acatgaatca catacaaggc agacaaaagc aacagcccca
     2281 tcaacaaaag gatgatgctg acagagcttt ggaggaacgt atatttggaa agcatgctct
     2341 ccaaattctc ccgttgcaac tcgatctggt gctgatagtc gaccacctgt tcggactgga
     2401 taaacagcgt cccggcattg ttcttatcga tcaaggcgga agaaagtaag tattgccggg
     2461 acacatcttc cccgttcaat atctgcatgg ctacgcggat agctaagctc ccacccgtcg
     2521 gatacaggat cgaagcagcc aactccccgt gcatgacagc ctccagccct gaaccgcgtc
     2581 ccgaaacagc atcgatgccc acaaagcgaa tctggtccgc caatccggga tgcttcttct
     2641 cgattgccct gcgggcagcc attgccatca catcgttatg ggcgaacacc acgtccacct
     2701 cctccaacga atccattttc gcaatctcct tctccaccgt ttccggcttc cattttccgt
     2761 atatttcctt caccttggtg cgggagttca agacatccat aaaaccgcga tggcgatctt
     2821 gtgccggaga agaaccggat aagccccata cttccagcac ggtaggatat ttctctttca
     2881 cctggcggtt cacgaaaaat gccgcctgac gaccgatctc gtaattattg ccgccgatat
     2941 aagtcgtata ttcgtccgaa ctgatcttcc ggtctaccag gatagtcggg ataccggcac
     3001 ggtaggcctc aatcgcaatg ggagtgacag gttccgattc gttggcggag ataatcagca
     3061 gatcgacctt ccgttttatc aggctgcgta tctgctccac ctgcaacaaa ctgctgtccg
     3121 cagcatcctc gaccaacagg gagacacccg gatattcgga ggcctgcacc ttcatatcca
     3181 gcaacatcga cttgcgccag gaaccctcaa gtgtacactg cgagacgcca ataacatact
     3241 tcttcttctc cgaatctgtt ttgcaggaaa aacagaatgc cagaagtaag accagtagag
     3301 cgtaataagt tagagcaggt ttcattctgt tttgtttaca ggtttctgca aatgtacgga
     3361 gaaatggcat accagccaat atttattttg tacattcgtc cctcagaaat caattattcg
     3421 catgaagatc ataaacgaag ctctattgga cgaaacgacc ggacgtgcca aacagtcgcc
     3481 ccgactacgc atgaactaca actttcatga acgtttggac gatcccgtca accgcctgct
     3541 caatgccctg gagccgggaa cctacctccg tccgcaccgt catctgaacc ctgcaaagga
     3601 tgaaatattc cttctgttac gcggccgcat tgctgttttc ctcttcgaca acaaagggga
     3661 aatcaccgaa acgcagatac ttgatccgaa agaaggtgcc tacggcgccg aaataaaagc
     3721 gggaacatgg cacggcctgt tagtcctgga atccggctct gtcatatatg agatcaagga
     3781 agggccgttc gccccgcttg ctccggagaa tttcgctccc tggagtccgg ctccggaaga
     3841 tacggaaggg gtggaaaaat atatggaact attggggaaa gcaatataac cccggcaggt
     3901 ttattatctc ccccgccgcc tatcccctat cccccaaaaa gctatatctt tttctcccga
     3961 aagctatagc ttttgcagga aaaaggtata gctttttttg gggttcgaag agcctttttg
     4021 aggaaaaggg caaaaaaggg ccaaaaaggc atcgtgtgtt tttgggtgaa ggggggacgg
     4081 taacctctta cggctataac acactatacg attgacagac aacaatataa atccatacat
     4141 ataacatcct cccctccttt tccccttctt tttatctcct ttttgccacg tcttccctgc
     4201 aaggtaaact acaagcaaaa ctactccgga aaatcctcca accgccagca tgggtgggaa
     4261 tacacctgcg catttgaaat tgtagcggat gcctttttta ccctttcgtg tccttttatc
     4321 tcgaaaggag gggtacgctt ccacatatca cactaataat caatgcataa caatttctcg
     4381 atacctgcca gcacaaagtc atttgcctgc aagccgagtg tgttcaaata ccaacatctg
     4441 acaatgcttg cagtcaaact gcaaccggag gcacgtatct ttataaagca gataatacgg
     4501 ctccttatag ggagacttgt tcttctgata agtaggacac caccccatgc tgtagcgcag
     4561 gcagtgcttg gtaaacatca gcggaacatc tttccgggga gacagttcga aagccgggtc
     4621 aacctgttcc accccgtggt cctggtagaa cgaacgggct ttcccgttgg cgacattccc
     4681 caaatacgtc aggctgcgtt cagggaaagg tatcggctcg gacagccgca cacgtttcac
     4741 cgtctcacga ggataacggg cacggcgaac ttccaacaac ttctccactc ctctacggcg
     4801 catatcggcg agcagagaag agggaacgaa ccagttttca gacaaaccga ccaccacctc
     4861 cgaggcctcg aaaggggtat tccccaactt agatagctgt gtccggatat tatcctgttg
     4921 ttcacggcga gccaactctt ttgcgaacgg ctcggccagc atgatccgtg cacccgtctc
     4981 gtcctccatg caaagcgtaa agccgaaagg attgtccagg aactcgattt tcacagacag
     5041 cctgcgttcg gcggaaggct tggcgagcag cttatcaaag acctggtcga aattgcggta
     5101 aagcggagtc ttgggggcaa gctgcggcat atccagcgga aacacccggt tcgcctccac
     5161 ccggttgacg cggaagccct ccaactcgcc tttcctatta aagaaaacaa gcccgtctcc
     5221 gttgttcaac tgcttcaagc cggccacggt aaaggaattg cctttgatct ctttgaccgt
     5281 cccgacaggt tcacccagcg atttaggcgt attgaaagcg gtaatatctg ccgtccgccc
     5341 ctccaaaagg aacggggtga agcctcggtt aaagctcttt tcggctaccg gctcgaacgt
     5401 ataagtgctt cgtccggcag aagcacggcg atattccgga cggcgggaca ggacagcgtc
     5461 caacttcttc cggtaataag ctgtgatatt cttgacataa tcgacatctt tcaaccgtcc
     5521 ttcgatctta agggaagaga cacctgcatc caacagggct tccaactggt cggaacggtt
     5581 catgtcctta agcgaaagca ggtgtttatg ggtgacgatc tccgctcctg tcgcatcgac
     5641 catcgtatag ggcaagcggc agtattgggc gcactcccca cgattggcac tgcgtccgct
     5701 caaggcggca ctcaggtaac attgcccgct atagctgacg catagggcgc cgtgcacgaa
     5761 tacttccaac gggacggtag tcgcttccgc tatccggcgg atctcattca gcgagagttc
     5821 acgtgccagc actacctgcg taaagccggc ggcctggaga aagcgaacct tttccggcgt
     5881 gcgattatcc gtctgcgtgc tggcgtgaag cgggataggc ggcaggttca gccgggtaat
     5941 ccccatatcc tgtacgatca gggcatctgt tccggcatgc caaagatccc agatcatccg
     6001 ttcggcttcc tccaactcct cttctttcag gatcgtgttg agcgtaacgt agatacgggc
     6061 tccatacagg tgggcataat cgcaaagctc gcgtatatct tccaaagaat tgccggcagc
     6121 ggcacgcgca ccgaacttgg gcgcaccgat atagaccgca tcggcaccgt gattaatcgc
     6181 ttccatcccg caattaaggt ctttagccgg agagagaagt tctataggac gggattttgt
     6241 ttgcatgcta ttatttctta tttcttgatt acaaatcgcc caacttgctg atatcctcga
     6301 tacggaacgg ggtttcttga tagacatagt agttcagcca gttggtgaac agcaaattgg
     6361 catgaccacg ccaacggacc accggaccga gggccggatt gttattacgg taatagttgc
     6421 gggggacggc aatcggcaac cccttgttca cgtcgcgcat atactcgtcg ttcagcgtat
     6481 aaggcgagta ttcggaatgc ccggtgataa agaactcgcg tcctccacgt gccatcgcca
     6541 tatagacgcc cgactcttcg ctttcggaca agagcgtcaa atcgggaact ttcatcacat
     6601 cctcgcggcg tatctccgta tgccggctgt gcggcacata gaactcatcg tcgaagcccc
     6661 ggaagatcgg cacataaggt tcgcgcaacg tatggcggaa cacgccgaac atcttggcag
     6721 gcagatcata tttggggaca ccatagaaat ggtacaaacc ggcttgcgcc gcccagcata
     6781 tatataaggt agaagtcaca tgcgtacgtg cccaatcgaa tatctcggtc acttcctccc
     6841 aatagttcac ttcctcgaaa ggcatctgct ctaccggggc acctgtgata atcatgccgt
     6901 cgtagaaatc atcctgcatc tcgtcgaagt ctttataaaa ctcctgcata tgctcgatcg
     6961 gcgtgttctt gggagtatgg ccttttatct tcataaagtc aagctccact tgcaggggtg
     7021 tattactcag gagacgaaca aggtctgtct ccgtcgtgat cttcagcggc atcaggttca
     7081 gcacaaccac acgtagcgga cgaatgtcct gctcggacgc acgcaacgag tccatcacaa
     7141 agatgtgctc tttcttcaac agctcaacgg ccggtaagtt cttctgtagg tttaaaggca
     7201 tcttctttcc ttgatattat ttatatgagg cacaaagata gtgagaattt ctcttcctac
     7261 ccattgtcaa aatgatagta tgactgcatc tatttcaaaa taatagggca tctatccgga
     7321 attacacttg cgggtaatat tttttaacat tcaaatagac aacaaatatc cttttctact
     7381 atcaaattgc cttcctttga aaataaatca ttatttcccg cgttagtaga tgtataactt
     7441 aaaatggaat atgaagattc gtgcaatagc tacgctacta tttatattat tttcgatatc
     7501 tgctttcgga cagggacgtg ccaaaatcag cggttacatc cgcgatgcag acggcaatcc
     7561 gctggatttg gtcaatatcc gagtcaagaa cacgttaaac gggacgatga gtaatgaaaa
     7621 aggccactac tcgctttcgg tcgctaccgg cgactcggtg acgctgatct actcatgctt
     7681 aggctacaac aaggccgaga ggatcctgcc tctggtaacc aaagatatgc ggctcaatgt
     7741 gcagatgaac tatacatcac ttgaactggg agaagtcgta gccaccgcca tccgcaagca
     7801 gacaaccact ctcgaaaccc tgaatgccga ccgcgtcaag ctgctccccg atcctgccgg
     7861 aggaagtatt gaaagcctgg tcgttacatt tgccggcgtt acttccaata acgaactgag
     7921 ttcgcaatac tctgtacgcg gcggcagcta tgatgagaac atcgtatatg tgaacggact
     7981 ggaagtgttt cgtccgctgc tcatccgttc cggacaacag gaagggctga gttttatcaa
     8041 cccggacatg acagaagccg tcaacttttc cgccggagga tttgaagccc gttatggaga
     8101 caagatgagt tccgtactgg acatcaccta caaaaaaccg aaaggattcg aaggttctgc
     8161 ctccgccagc ctgttggggg ccaatgctta tgtgggaagt tcttccggca agttcacaca
     8221 ggtgaccggt ttccgttata aaacagggcg ctcccttttg aaaacaaccg atacggatgc
     8281 cgaatatgat ccgaatttta ttgacttgca gacctatatg acctaccagt ttgccccaaa
     8341 atgggagatc aacttcctcg ggaacctggc cataaacaat tacaaattca ttccccacac
     8401 ccgcgaaaca tctttcggaa cggctacaaa cgcaaagaag tttaaagtgt tcatgagcgg
     8461 ccaggaacgg gacaagttcg agacgctatt cggagcactc actttaaagc ataacctgaa
     8521 tgagaatacg gaactcggct tgcaggcatc cgcattcacc agcaaggaag aggaaggata
     8581 tgatatcgcc ggagattact ggctgggaga tgcagccgaa gaaggcggcg gggaaataga
     8641 gaatctatcc atagcacgct ataacgagca cgcccgcaac cgactgcact ccaacatcat
     8701 gaatgtcgga cactatggta tcgcccgcat gaaaaacaat acgttgaaat ggggtgccac
     8761 cgtccagttg gagaaaatca acgacaagat cagtgaatgg gaaaaacgcg attctgccgg
     8821 ctactcgcta ccgcaaggag gcggcaatgt caacgtgatc gccaaccttt tctcagataa
     8881 tgaactggaa agcacacgta tttccggcta tttgcaggat gtattcaagt tccgtaccaa
     8941 acaagggctg ttcacgctgg tcggtggtgt acgcggtagt tactggagct ataataagga
     9001 atttatattc agtccgcgtg cttcaatcgg tttcattccg aacttcgacc agaacctgac
     9061 attccgcttg gcttccggcc tgtattatca gtctccgttc tataaggaat tgcgtacgac
     9121 cgtgcaggac gaacacggca acagtatcat acaactgaac aaaaatctta aatcgcagcg
     9181 ctccatccat gtcattgcag gaggcgatta tacattccgg gcatccggca ggaatttcaa
     9241 agtcagtgcc gacatgtatt acaaaaagtt ggataacctg aatccttata cggtggataa
     9301 tgtcaaaatc cgatattacg gtgaaaactg cgctgagggc catgcgatgg gactcgatgt
     9361 caaattcttc ggtgaatttg ttccgggtac ggactcctgg atcagcttct ccctgatgaa
     9421 agcggagcag agcatccggg ggagcgaata tgtcccgatg ccaaacagcc aaggttataa
     9481 tgtttcgctt tttttccagg attattttcc cggttacaaa cgcgtcaagc tgaacttgaa
     9541 aggcgtcctg tccggcggcc ttcccgtcac agccccgcgc acaggctatg aggacggcta
     9601 tttccgcact ccgacctaca aacgtgtaga cctcggtttc tcttaccagc ttgccggggg
     9661 aacggatgcg attatggacc gcggattctt ccgcaatctc aagaacattt ggctcgggct
     9721 cgacattttc aacctgttcg acataaagaa tacaagttcc tattattgga ttaccaacat
     9781 agacaaccac cagtacgcga tcccgaatta cttgaccggt cggcagttga atgtccgtct
     9841 gattgttgac ttttaaattt atgatttatg atttatgatt tgcgatcggc acataaatca
     9901 taaatcataa atcacaattt ttctttccta attcataaaa aagtgtacct ttgtccacat
     9961 agaacaaaaa acaatattaa atcactaaat tattattgac atggaactta cacatatcga
    10021 acatttgggt atcgcagtga agagcatcga agcttgtctg ccgtattatg aagaagtttt
    10081 gggattgaaa tgctacaaca tcgaggaagt ggcagaccaa aaagtaaaaa ccgccttctt
    10141 taaagttggc cagactaaga tcgaattatt ggaaccgaca agcgaagaca gtacaatcgc
    10201 taaattcatc gaaaagaaag gcgaaggtat ccaccacatc gcatttgccg ttcccgacgt
    10261 acaggcagca ttgaacgaag ccgaatcaaa aggtgtcaag ctgatcgaca aagctcctcg
    10321 cggaggtgca gaaggcttgg acatcgcatt ccttcacccg aaatcgactt gcagcgttct
    10381 gaccgaactt tgcatgccgg gaaaataaaa aacaatggac aattgaaaat ggacaatgga
    10441 caattatttg atgctattta attgtcaatt gtcaattatc aattgccaat caaataagtt
    10501 catttctaac aacaaatcta tagtacaatg agtaaccaac ttgaaaaagt aaaggagctt
    10561 atcgcccttc gcgaaacagc tcgtttaggt gggggagaaa aaagaattga atctcagcac
    10621 aaaaaaggca aatacaccgc acgcgaacgt attgccatgt tgctggatga aggaagtttt
    10681 gaagaattcg atatgttcgt acaacaccgt tgtacaaact tcggtattga aaaaactaag
    10741 tatctgggcg acggtatcgt aacaggttac ggtacgatcg acggacgcct ggtctatatt
    10801 tatgcgcagg atttcaccgt gttcggtggt gctttgtctg aagcgctggc catgaagatc
    10861 tgtaaagtca tggatcaggc aatgaagatg ggagctcccg ttatcggctt gaacgactcg
    10921 ggtggtgcac gtatccagga aggcgtaaac gctttggccg gttacgcaga aatcttccag
    10981 cgtaatatct tagcatccgg tgttattcct cagatttccg gtatcttcgg tccatgtgcc
    11041 ggtggtgcgg tttattctcc tgccctgaca gacttcaaca ttatgactcg tggaacaagc
    11101 tatatgttcc tgaccggtcc gaaagtagta aaaacagtta caggcgagga cgttacacaa
    11161 gagcagttag gtggagcaag cgtacacacg accaaatccg gtgtggccca ctttgcagtt
    11221 gatacggaag aagacggttt gcagttgata cgcaaattga ttagcttcct gccacagaac
    11281 aacctggaag aaactccgct gatcgaatgt aaagatccga tcgaccgtct ggatgacaac
    11341 ctgaacgaca tcatccctga caatcctaac caggcttatg atatgtacga cgtaatcgga
    11401 accatcatcg ataacggtga attcctggaa gtacatgccg actatgccaa gaacattatc
    11461 gtaggtttcg cccgtttcaa cggccagact gtcggtatcg tagccaacca gccgaaagta
    11521 atggcaggct gtctggacag caacgcttcc cgcaaggcag gccgtttcgt ccgtttctgt
    11581 gacgctttca acattcctct ggttacattg gttgacgtac cgggattctt accgggtaca
    11641 ggccaggaat ataacggcgt tatcctgcac ggagctaaat tgctttacgc ttacggtgaa
    11701 gctacagtgc ccaaagttac tgtaacattg cgcaaatctt acggtggcgc ttactgtgtg
    11761 atgagttcca aacatctgcg tggcgatatg aactacgcat ggccgacagc cgaaattgca
    11821 gttatgggtc cgagcggtgc tgtagaagtg atcttcgcaa aagaagtggc tgcctcggaa
    11881 gatccgaaag cttgcgcagc agaaaaagaa gccgaataca aaaaagcatt tgcaaacccg
    11941 tataatgccg ctcaatatgg ctatatcgac gatgttatcg aacctcgtaa cactcgtttc
    12001 cgtattattc gtgctttaca acaattgcag actaagaagt taagcaatcc tgctaagaaa
    12061 catgacaatc tgcctctata attcttaaaa caggaaatga ttatgatgaa taagaaaata
    12121 ggggtattgc tgctgtttgc tttgctcgtt tcattcgggg caaaagcaca gctcgcaacc
    12181 tccatgcgaa taaatgaagt gctggtcatc aacgaagata actttgtcga tgactacggt
    12241 aaacgtcacg gctggatcga attgtataat tcctccgccg gaacggtgaa catcgcagga
    12301 tgttttctga cggacgacaa aaacaatccg aagaaatatc cgatccctaa aggagatgta
    12361 ttgacacaga ttcctccggg acagcacgtg ctcttctggg cagacaatga accggaccgg
    12421 ggtacattcc atgtcagttt ttctttggat ccgaccaaag agaactatgt agccttatat
    12481 aatgcggacg gaaaaacctt gatcgacgaa gtgactatac ctgcaggaca ggtagcagac
    12541 gtcagtttcg gacgtattat cgatggtaag gaagaatggg cacagttaac aaaagtaact
    12601 cccagcacaa ataacctgac actggactca aatgaaaaga tagacaattt caaggaaaac
    12661 gactcttggg gtatcggtat gaccattact gctatggcag tggtattcct tggattattc
    12721 ctgttgtatg ttatcttcaa acagattgga aaaatttcca tcgccgtcag caaacgaaat
    12781 gccaagaaag cagctggaac cacacctatt gcagacaatg caggacagga atccggagaa
    12841 atattcgcgg ccatcggtgc tgccctttat gagatcagcg acgacaacca cgatatcgag
    12901 aataccgtgc tcacaatccg taaggtgcaa cgtgcttatt caccctggag ttccaaaata
    12961 tacggtttgc gtgaaatgcc caaaaagtaa tcacccctaa aaacaaacaa gaatgaaaag
    13021 tttcaaatat accatcaatg gtaatgtata taaagtacat attaactcaa ttgtagaaga
    13081 tgtagccgaa gtggaagtaa acggcactcc ttatcaggta aaaatggaga aaccggctaa
    13141 aaaacaaatg gtgacattaa aacgtcccgc acaagctcct accacagcaa gtggtgaacc
    13201 tgttatttca cgtccggcag cctctacaac caaaggagca gtcaaaactc cgctaccagg
    13261 cgtaatcctg caaataaaat gtaacgtcgg cgacacagtg aagagaggac aaaccctgct
    13321 tgtccttgaa gctatgaaga tggaaaacaa catcaacgcc gatcgtgacg gcaagatcat
    13381 cgaaataaaa gtaaacaagg gggattcagt gctggaaggt gccgacctcg tcgtaatagg
    13441 ataatattat gttaggatca gtattattac aagcagcagg agttgctcat gaaagttttc
    13501 tccagtttct ggggaaaaat cttgagctat tccttacata tacaggagtc tacaacgcga
    13561 ccccgggtca ccttatcatg atccttatcg gtctgttgtt catatttctg gctattaaat
    13621 atgaatttga acccatgctt cttatcccga tcggcttcgg tatcttaatc ggtaacatac
    13681 cttttaaaga tgccggacta caagtcggta tttatgaaca gggttccgta ctgaacatcc
    13741 tttatcaggg tgtaacctcc ggatggtatc cgccactgat cttcctcggt atcggagcca
    13801 tgacagactt ttcggcattg atctccaatc caaaactgct gttgatcggt gctgctgccc
    13861 aatttggtat ttttggtgca tatatcatcg ctctccagat gggattcgaa ccgaaccaag
    13921 ccggtgctat cggtatcatt ggtggtgctg acggtccgac ggccatcttc ttgtcttcca
    13981 agttagctcc gaacctgatg ggtgctattg cggtatcagc ctactcttat atggcactgg
    14041 tccctatcat ccagccaccg ttcatgcgct tattgacaac taaaaaagag cgtctgatcc
    14101 gtatgaaacc accgagagct gtttcttcta cagaaaagat cgtattcccg atcgtaggtc
    14161 tgttgctgac ttgcttcctg gttccttccg gtcttcccct gttgggtatg ttgttcttcg
    14221 gaaacttatt gaaagaaagt ggtgtaacac gtcgtttggc tgaaacagct cgtggtccgc
    14281 tgatcgatac aatcacaatc ctgttaggta tcacggtagg ggcttccaca caagcaaccc
    14341 aattcttgac catcgattcc gtcaagattt tcggcttagg agctttgtca tttgtgatcg
    14401 caacttgtgc tggcgtattg ttcgttaagg tattcaattt ggttttgaaa gaaggcaaca
    14461 aaatcaatcc gcttatcggt aatgcaggtg tttctgccgt ccctgactct gcacgtattt
    14521 cacaaatcgt aggtctggaa tatgatccga ccaactacct gttgatgcat gccatgggtc
    14581 cgaacgtagc aggtgtaatc ggttctgccg tagcagccgg tatcctgtta ggattcttag
    14641 gataagtcct ttattttaca taaaaagcct ccgcatcgcc tcgatacgga ggctttttat
    14701 gtaaaataaa gtataaattt cacctggtaa ggcaactaaa cagtgccaca tcttatccaa
    14761 acttcacgag tatccgggtc tctccatctc ctacacccaa gtctcgagag agtgctcaaa
    14821 ctgtttattt gcaaaaacct gcctatcttc atcaaaaaac gaaccatttt aacatatttg
    14881 gaatccgacg aatatagcca gcataaaata cgccctgtaa aggtgtgttc tttacagggc
    14941 gtatatatag aaaatttatt tatcctcaga acagcggatt agccaccttt tccttcaaca
    15001 aggccagatc gactacttgg cggatatcat ccacataatg gaaagtcagt cctttcagat
    15061 agtcgggctt gatctcttcg atatctttct tattctcttg acagaggatc agttccttga
    15121 ttccggcacg tttggctgcc aatatctttt ctttgatgcc acctaccgga aggactttac
    15181 cccgcaacgt gatctcgccg gtcatagcca aattactgcg caccttacgc tgcgtaaaag
    15241 cagacaccaa agatgtgacc atcgtgatac ccgcactcgg accgtctttc ggaatcgcac
    15301 cctcaggtac atggatatgg acattccagt tctcgaacat accttcgtca ataccgaata
    15361 gcccggcatg cgaatgaata tattcaagtg ccaacatggc agattctttc atcacgtcac
    15421 ctaagtttcc tgtcaaagtg agctttgaac cttttccttt actcaaactc gattccacaa
    15481 acaggatctc accaccgaca gccgtccagg caagtccggt tacgacaccc gcatagtcat
    15541 ttccctgata tttatcacgg gtatattcga ctgctcccaa ataatcgtgc agatcttcgg
    15601 ggcgtatctg tgcgggaagc tcctcgtcgg aagccagctt acgggccaac ttacgcataa
    15661 tcttggctat ctttttatcc agttcacgaa cgccgctctc acgggtgtaa gattcgatga
    15721 tcgcctgcaa cgtctttttc gggaacttca cttttccttt cgacagaccg tgaatctcca
    15781 attgtttcgg gaccagatga cgggcagcaa tttccacctt ctcttccatg atataaccac
    15841 tcacttcgat caactccata cgatccagca acggctggga aatcgtgttc aagttattgg
    15901 cagtcgcgat aaacataact ttactcaagt cataatctat atccagataa ttatcatgga
    15961 aagcattgtt ctgctccggg tccaacacct caagcaaagc ggaagctgga tctcccttga
    16021 aatcattcgt taccttgtca atctcgtcaa gaataaacac ggggtttgaa gttccagcct
    16081 tctggaggtt ctggatgata cgtccggaca tcgcaccgat ataggtacgg cgatgaccac
    16141 gtatctccgc ctcgtcatgc aaaccgccca acgaaacccg aacatacttg cggtgcaagg
    16201 cttctgcgac cgattttccc aacgaagtct taccgactcc cggaggcccg tacaaacaga
    16261 tgatgggcga cttcatatcg cctttcaatt tcagcaccgc caaatgttcg atgatgcgct
    16321 ctttcacctt ctccagcccg tagtgatcac gatccaggac tttctgggca tgggcaagat
    16381 tgaaattatc cttgctgtat tcgttccaag gcagattgat gatcgtctgt acatattgcg
    16441 tttggatgga aaaatcagga gattgcggat gcagacgttc caacttgcgc acttcctttt
    16501 caaacgtttc ggctacagac ggcgaccatt ttttcttggc agccttttcg cgcagttcct
    16561 ttatctccaa ctcgttgata ttgcccccca actcttcctg gatggtcttg atctgctgct
    16621 ggagaaaata ttccttctgc tgctggttaa tatcctcgtg cgtcttcatt tggatggatg
    16681 ttttcaattc caccaactga tactcccgat tcaggatgaa caaaagacgg tacgctcggt
    16741 ctttcaggtt accgatcaac aacaaatcct gtttttcaga cgatccgttg ggaacattgc
    16801 aacaagaaaa attgatcagg taaagaatat ttttattatt ccttattgaa aatatcaagt
    16861 cgcggggcgg ttcggaagca gctccgagca tcttgatcgt caaatctttg atagtcgaga
    16921 caagcgcctc gaactcgcgg tcggacttgt ccggcatgac gtcctcaagc aatttgatct
    16981 ttccggttag gtaaggatcg taagcggaaa gctcttccag ttggaaacgc ttcttaccct
    17041 gcaggatcac ggtcgtcgtc ccatcaggca tttcaagcac gcggacaata tcagccacga
    17101 ctcccgtcgt atacaaatct tccatcttcg gatcttctgt attcatatcc ttctggcaaa
    17161 ccactccgat cagacttttc ttgtgggcgg cttccttgat caggcgcatg gatttaggac
    17221 gaccgatcat caccggcata gctacgcccg gaaacagaac catattccga agcggaagaa
    17281 tgggcaattc ctcccccacc ttttccatac cttcggtaaa gtcttcatca acatcacaat
    17341 ccgtgaggat aggcattact ataccaatat tatcatccag gtcgttatac gactcctcgg
    17401 caaacatcgt tactttatct ttcttcatat attctttgtc atagttgcgg aatattcttt
    17461 tatcgaccgc aattctattt tgtacaataa acgtgccaaa gttactattt ttaactcaat
    17521 tctgactact tttgcacaaa acaattgaca atggaccatt gacaatgaac aactattcag
    17581 tccactccaa tcgtcaattg tcaactatta attgtcaatt gttatgtcaa atcctttttt
    17641 ccaattcaaa caattcacca tccgccatga taaatgcgca atgaaagtag gaactgacgg
    17701 tgttctgctc ggcgcatggg ccggaataga atcatgcaac cgcatactgg acatcgggac
    17761 agggactggg ctaatcgcca tgatgctggc acaacgcagc aaggcggtta tcgacgctat
    17821 cgatatagat gccgaggcct gtcttcaggc acaggaaaat gcagaatcct ctcctttcgc
    17881 cgaacggata aaaatccagc attccgccct gtctgatttc gcacaaaccg atacgggctt
    17941 atatgacctg atcgtatcca atccccctta tttcgtcgat tcgttgaaat gtcctgacca
    18001 gaagcggaac acggctcgcc acaccgacac gctgacattg gaagatttgt tgcaggacag
    18061 ccgcaaacta ctcgccccgc agggacgcat cgctctcatc ctgccctacg accaaaaaga
    18121 acgtcttacg gattgtatcc gaacacaaaa cctgttcctt tcgaaagaaa cctccgtcat
    18181 acccgtaccc ggtgccgagc cgaaacgact gttagccgag ctaacggcag agccacccgt
    18241 ttttcccaca ttttccagcc agttgaccat tgagattgca agacatcagt acactgacga
    18301 atatgtcagc ctgactaaag acttttatct aaagatgtaa gggagtttct tatcgaagaa
    18361 acgagtcact tcgccaaaca ggttctgcac ctcctccgta aaggaaacag tttccggtgt
    18421 caatacgttc aatgatttag gaaggacgga gatttcaatc cggctgtccg ccatgattgg
    18481 ctcgccatcc aggtgcatga ctcccggatt ctggcgaatg atcgtcacct cttttccttt
    18541 gaatgttttg atcttgctgt tacggtcgat ctgcttcgta aacagctgga tagccaacgg
    18601 cgctatgtcc agcggaccga aaggggaaag gattgtaata tccattttac catcctgtat
    18661 attggcatga ggagcaataa acgcattgtt gccatactgc gaagcattcc cgcaagccac
    18721 caaaaacgcc ttttccttga ctgtctgact gtcgatcaag agctcataag gctcgggttg
    18781 gtaactcaga tattcctcca ccgtattctt tatataagta agcgacccgc ggcgtttctc
    18841 ccctgcaaac ttctggctga ccgccgcatc aaaaccgact ccgcaggtac agaaaaaaat
    18901 acgtccgttc gccttgcaac aatcaattgt cgaaacgtgc ccctttacaa tcagatcgat
    18961 cgcccggcgt acatccatcg gaatatgcag ctcacgcgcc agaccattac cggaaccttt
    19021 cgggataatc cccagcacag catccgaatg gagcatggcg cgggcaatct cgttcacagt
    19081 cccgtctccc ccgaccgcaa tcacgcaatt ggctccttta tcgagggctt gccgtgtcag
    19141 ttcactggca tgtccgggat attccgtaaa agaaatttcc acacaacaat ttccgcccgc
    19201 aaaggcggtt tcaatcattt tcggaatctt ccttttcgaa ccgacacccg aaatcggatt
    19261 tataatagcc tgtatattga ttgtctgtcc ctccattctt gctgctactt actttgagag
    19321 gacaaaaata atgcttttgt aaaactttta aagcatttcg gctactataa gttatttttt
    19381 tactactttt gcggctggat ttgccgaaac atagatatta tgtagtaagc agatctgggt
    19441 tcttttagaa taacaacgta gcgagaaaat cattctctgt taattataat atgaaacttt
    19501 tacaagagaa actatcaaag tacgatgcac ctcagcgggc tatggccgca ggaatttatc
    19561 catacttcag aatgattgaa agtgatcagg atacagaagt aatgatcagc ggtaaaaagg
    19621 tcctgatgtt tggttctaac gcctatttag gcttgacaaa ccacccgaaa gtaaaagagg
    19681 cggcaattga tgccattaag aaatatggta caggttgtgc cggttcacgc ttcctgaacg
    19741 gaacgctgga tttgcacatt cagttggaaa aacgtctggc cgaatttgtc ggaaaagaag
    19801 atgccattgt ttattctacg ggatttcagg taaacttggg tgtagtatcc tgcctgacag
    19861 gacgtgaaga ctatattatc tgggacgagt tggatcatgc atccatcatc gaaggacacc
    19921 gcctttcctt ctctaccaaa ctgaaataca agcataacga tatggagtct ttagaaaagc
    19981 aactccagaa atgcgaaccc gacaaggtga agctgatcgt tatcgacggt gtgttcagta
    20041 tggaaggcga cattgccaaa ttaccagaaa tcgttgcgtt agccaagaag tataatgcaa
    20101 gcgtgatggt agacgaagct cacggtctgg gggttctggg cgatcatggt cgcggaacct
    20161 gtaaccattt cggcgtaact gacgacgtag acctgattat gggtacattc agtaagtcgc
    20221 ttgcttctat aggtggtttc atcgcttcgg acaaggagac gatcaactat ctccgccaca
    20281 actcacgctc ttacatattc agtgcaagta atactcccgc cgctacagca gcagccggtg
    20341 cagcactcga tatcatgctg agtgaaccgg aacgcatcga gcatctgtgg aaactgactc
    20401 actatgcatt ggacggattc cgtaacatgg ggtgtgaaat cggccatacc tcaacaccga
    20461 tcatcccgtt gtttatccgc gacaatgacc tgacattcct gatcgtaaaa gaattgttcg
    20521 aagccggtat cttcgtaaat ccagtagtct ctccggctgt tgcacctgaa gatacgctga
    20581 tccggttctc gctgatggca actcacacga tcgaacagct cgactacgca ttggaagcaa
    20641 tacacaaagt atttaaaagt cacggcctgg ttaagtaaat cagtacggac aatgatatcg
    20701 aaaagggcaa agcggaacat tctgttttgc cctttctctt tataattcat tcttcatttg
    20761 ctacgaacca aatattttga ctatttttgc gtaattgtac gcactataaa tacattatat
    20821 ataccagaca aatggatttt aaattaaata caggaagttg ctgcatgggt aaaaaaggat
    20881 gcagcaagat acaaaataat aagctgaaca cctacgactg gctttgcgac gtgcccgatg
    20941 cggcaaatgc aaccgattac gtggaagtgc agtttaaaaa cacccgcaaa ggatattacc
    21001 tcaacagttc caagatacct ctggaaaaag gagatttagt cgcagtggaa gccagtcccg
    21061 gacatgacat cgggactgtg acgctgaccg gcaagctcgt ccttctccaa atgaaaaaaa
    21121 acaatgtccg taccggcgaa ggtaacgagc ctaaaaaggt atatcgcaaa gccaaaccga
    21181 ccgatatcga gaaatacgaa gaggcgaaag ctaaggaaca cgccacaatg atccgttcgc
    21241 gacagatcgc tgccgacttg ggactgaata tgaagatcgg ggacgtggaa taccagggtg
    21301 acggcaataa ggcgatcttt tattacattg ccgacgagcg tgttgacttc cgccagttga
    21361 tcaaagtact tgccgaagcc ttccgtgtcc gcatcgagat gaagcagatc ggtgcccgtc
    21421 aggaagccgg acgcatcgga ggtatcggcc cttgcggacg agaattgtgc tgttcaagct
    21481 ggatgacgag tttcgtatcg gtagccaccg gagccgcccg ttatcaggat atctccatga
    21541 acccccaaaa gttagccggc caatgcgcca agctgaaatg ttgcatcaac tatgaagtgg
    21601 atgcttatgt ggaagcacaa aaacgtttgc cgtcccgtga agtggtgctg gaaacaaagg
    21661 acaataccta ctatcatttt aaaacggata tcttcaaacg ggaaatcacc tactctaccg
    21721 ataaatcgtt cgcggccaat ttggttacga tctccgccaa ccgtgccttc gatgtgatca
    21781 acatgaacaa gaaaggtatg aagcccgtca ctctcgaagc cgataccaag ccgcagccac
    21841 ctaagcgcga tgcccaggat atcttggggc aggacagcgt tacccgtttc gatgcttccc
    21901 tgaaaaagaa gaaaaagaaa cgcaacggaa acggcaacaa ggaaaatctg ccgaaagaaa
    21961 ccgtagccaa caccggcagc gaaggaaaca gcaaacctac caacggagaa aaagcgaacg
    22021 gcaacaacgg caacgaaaat aaaaacggta aaggaaacgg taacaggaac ggaaaccgca
    22081 accgtaacaa cgggaaccga gacaacaacc gcgagcggga gaatcgcgaa aacaaccgcg
    22141 acaacaaccg taacagaccg cgtccgaacc gagtaaataa cgataagcaa ccgaataatg
    22201 acaaacctca gcaacaagct aagcctgcta ccaaaccgga ctccaaaccg gaaaacaagc
    22261 cggacacaaa gccggaagct taaaggaatc attgccgtac tgacttgttc cctattcttt
    22321 tcctgcgaaa acccagcctt gtacgaccag taccaggcga tcaacaatat cacgtgggaa
    22381 aaggataagg aatactattt taccttcgag gtgaaagata tatccgttcc ttacgacctg
    22441 acactggaag taaggaacaa caacctgtac ccttatcaga acttatggct tttctgtagt
    22501 gaagagcagc cgatcggccc acttcgccgg gataccattg aatgtatact tgccgacgaa
    22561 ttcggcaaat ggcacgggca tggcatttcc ttatatcaaa gcagctttcc catccattcg
    22621 caatataagt ttccgtatgc tggacaatat acgttcagtt tccgacaggg aatgcgcgac
    22681 gatgctctga aaggaataca ggaaatcggt ttctcggtcc gcccctccca ttgacggccc
    22741 cttcatccgc cccgagcacg agcattcgct tgctaccgtt cccttctgga ggcatccaga
    22801 cgaaggaaga taaagagcaa gatcgtgaat ccccaaaggg aagaaccgcc gtagctaaag
    22861 aaaggcaatg gaataccgat cacaggtgta agccccgtca ccatcccgat attaatagcc
    22921 agatggaaga aaaagataga agcgacactg tagccataca cccggttgaa agtagagctt
    22981 tgccgctctg ccaacacgat cagccgcagg atcagaaacc cgaacaacaa caggactatc
    23041 gaggctccga tgaacccctg ctcttcacct accgtacaaa agataaagtc ggtatcctgc
    23101 tcaggaacat acttcaactt ggtctgcgta ccgttcagaa agccttttcc ggtgagtcca
    23161 cccgaaccga tcgcaatctt cgactggttc acattatagc cggcaccgct cggatcgtct
    23221 tccaatccca atgaaacctt gatgcgtatc tgttggtgcg gttccaagat atcggtaaac
    23281 acataatcca ccgaatacat aaaagccagt gatcccaatg caaaaacagc gatcagcaca
    23341 taatgccata cccagttgcg gatagaaagg aaaatcagat agcagactac cagcaaaacc
    23401 aatccgatcg atatcaggga ataatcgacc ggcataaaga atgaggcagc atatccccct
    23461 aaacaggcaa tccccacagc acctaatatc gcctgtatcg cacgggtatc tttcttttct
    23521 atttgtatca ggataaccgt gatcaacaag atcaaagaag atacaagcaa ctctcccact
    23581 gccgtagctc ccgccgtcac atccgagaac ttcatgctgg tgacaaaaaa gacaaccgca
    23641 cagactcccg acagaagaat atatcccgac atcccctccc ggtataacat caggaagaaa
    23701 gccaggtaaa ccaacgccga acctgtctct tgctgcaata gaatgcaaat catcggcagg
    23761 aatataagcg acaagacgag tatgaaattt ttaggtacag tcaacttgaa accatacgta
    23821 ttcatcagct tcgcgacagc aagtgccgtc gcaaacttgg cgaactcagc cggttgcaac
    23881 ctgacaggtc ccaaaacgag ccacgaatgg gaacctttta tgttcggagc cagaaagatc
    23941 gtagcaatca gcaacacgat gacaccggca tatatcagat aggcgaaaac atcaaaaaac
    24001 tcactctcca gcatcaggat cacaaagatc aaccctaccg ataaccccat ccacatcaac
    24061 tgcgaaccag gacgccccga cgggtcgaac agccccacgt tatcgaattc ataactggca
    24121 ccgcagatac taaaccaacc ggcgacgacc aaaactacat aaagaatgat cgtcaaccag
    24181 tcaaccgtct tccatatttc tgtcttccta taactcacga ttcggtaaag ataaaacgtt
    24241 tggcgataca accgcatttg acattgtctc ttccagcaac ttgttctctt ccgagatctc
    24301 gcctttcaga tacttctcca tcatcaactt gccgatcggc acaccgtaag tcgcaccaaa
    24361 accaccattc tccacatata cgcaaatggc caccttcgga ttccgataag gagcaaaacc
    24421 gataaaagcc gagtgatctt tcccatgcgg attctcagct gtaccagtct tgccgcagac
    24481 ctcaatatcc ggaatagcca cccctcggca agtgccacct ataacggcat tccgcatacc
    24541 ttcagcaacg atttcataat tttcgcgatt caccatcgtg taccgtttat ccgtgtaaag
    24601 ggaatccaac ggggtgtcct gcacctcctt cacgacatgc ggagt
//
