LOCUS       NZ_KB899815.1          14978 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KB899815.1 Cohnella laeviribosi DSM 21336
            F560DRAFT_scaffold00008.8, whole genome shotgun sequence.
ACCESSION   NZ_KB899815
VERSION     NZ_KB899815.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:32:28
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 118805
            Orig. end    :: 133783
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14978
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[128805:132287]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13482
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14978
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14978
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(474..1853)
                     /locus_tag="ctg8_115"
                     /transl_table=11
                     /translation="MERWKSRYFPALAEFALSEGGTITDKAKLMHQLQGVSSDDILSHH
                     EASVKDLLYNAEAEDRMTLMHRSLLFLMEILTSVRLPEAAAGEEDASAKRLKESAVQSL
                     PLQEERPSKFETVLQHMDSGIALFDSEGHLRFLNVQMSRLLQAPRRALIGHSLRQLMFH
                     PYLRKSIRMIFLRMYKEMVYYRRFNGEFQDAHGRFLLISITRIDELDGDYLVSVKDVSE
                     FKHIEQSAFQNDKLAMLGKIAASIAHEIRNPLTSIRGFIQLLKPYLETIGKQEYARIIL
                     SEIDRANDIIFEFLNSSKPSAPMKQHISVGMLLKESILLFESEANMKGCELHFEIYDPV
                     MQVAIDVKQIKQVILNILKNSMDAIQDSGDERKGLIQVTANRENRYAVIRIRDNGKGME
                     RSTMARLFDPFFTTKQDGTGLGLSVSYRIIRNHGGTIQVDSRLNEGTEFIIYLPLAGEK
                     E"
     CDS             complement(1917..3299)
                     /locus_tag="ctg8_116"
                     /transl_table=11
                     /translation="MNRAVILSLEKRKAIVLAPGGQFVRVKRLPHFRIGDEIEWARTGA
                     RRGLLGGRRTAAILGASAVAAFVLLLGLWWFQTPTVVAYVSMDVNPSVEMGIDSREYVR
                     ELRALNADARPIVAAIEYKGQTVEDVTARLAEELASRKLLDSGGEVVLASVAVGKVDAE
                     WEAEIIGSMKKAIEQTAKRLGGASDNAPEIMAVSVPAEVREEAKKSGVSTGKMAFWLKA
                     ESQGHEVPLETLRHESMKTIASEWGGVQQVLTGNKPNPDTKSESASSALKNGSERDEWN
                     KLLAALKDKVEEDRKKRDELRKQQRQENRKKQNYREKQENGGRNANQERSGKQESNARQ
                     TSGGALVTRDHRDRTEKAGKENKIGKKKDREDRRGDDNRGARGGKTGSGNRRYGDGGER
                     NNGHRNREVRNENKIKGQNSGSLISNASNRQTENHDRNPSRRHDGGSKRSADRNQDGKS
                     KD"
     CDS             complement(3296..4135)
                     /locus_tag="ctg8_117"
                     /transl_table=11
                     /translation="LSIRTLYLWGEFLLLALWKKWVGHRSDSDGAPEGDTPEAMVASIQ
                     QGNEELRNELIQRYRPFILKTASRFCKRYIDPARDDEFSVALLAFDEAINGYSAQSGGR
                     FLTFASQVITRRLIDYARKEERHASLVPYSALEGDKGEGASLLSQVEAKEALEAYAQDQ
                     DRETRLEEIKALAEELAGFGISFADLSEQSPKHLDSRNMLLGIGRRLAANPVLFAMLKE
                     RRQLPLKELCEAEQVSRKTLERNRKYLIATALIAGGPYRHLKPYIESPEKGMEGETP"
     CDS             complement(4238..4663)
                     /locus_tag="ctg8_118"
                     /transl_table=11
                     /translation="MSFCCGASMIGTKGTLKHFRTRIHNVPILFCPVCHRVEVHYLVEN
                     EYEILAEYAHGDGASEVDFNDYVDESDKALHENCINHEDEDPLYIVQYQIDMALDLLTF
                     AKELKDAEWEQQLKRRLGMLAQRRHKLRFKRTSGGAY"
     CDS             complement(4919..5467)
                     /locus_tag="ctg8_119"
                     /transl_table=11
                     /translation="MAERLVGLPAPDFTLETALGDGQGFGKVSLSDYKGKWLVFFFYPL
                     DFTFVCPTEIVALSEAAEQFRALNTEILGVSVDSIHSHRAWINTPKSENGLGKLNFPLA
                     ADITKKTARDYGVLIEEEGVALRGLFIIDPDGIIKYQVVNHNDVGRSVDETLRVLQALQ
                     SGGLCPINWKPGDKHLVAK"
     CDS             complement(5604..6683)
                     /locus_tag="ctg8_120"
                     /transl_table=11
                     /translation="MADVKKIAVISGDGIGPEVVAEAIKVLKKTEELYGYKFELEYGLF
                     GGIAIDEKGTPLPQETLEICQKADAVLLGAVGGPKWDNNPKELRPETGLLGIRKALGLF
                     SNIRPAVVFDCLKDASTLKPEVLEGTDLIVVRELTGGIYFGDKFRREGEGGQEAVDTCV
                     YSVSEVERIVRQAFEIARKRRKRLASVDKANVLETSRLWRETVNRIAPEYPDVELEHVL
                     VDNCAMQLLRRPSSFDVIVTENMFGDILSDEAAMLTGSIGMLASASLGEGSFGLYEPVH
                     GSAPDIAGQGIANPIATILSVALMFQLTFGYLEAGKAIEDAVKKVLDAGHRTSDIAVDK
                     SKAVSTSEMGDLIVAALAK"
     CDS             complement(6968..8161)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_121"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.1e-44, bitscore:
                     145.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYRFSAKMGSFSSSAVREILKLTQGNSIISFAGGLPAEEHFPVT
                     AVSEAFQRVMEQGNKALQYGLTEGYLPLREALCARMARKGVRVTPDHMLLTTGSQQAID
                     LLSRIYLDPGDVILVERPTYLSALQVFRSYGAVPVSVEGDADGPDLDDLAAKLERYKPK
                     MLYVIPTFSNPTGKAWSEQRRRGTLELCRRTDTLILEDDPYGELSFGDGSVTYPSIFSL
                     DEHPEGSGVVYTSTFSKTVAPALRTGWVIGDSKLIRNMTQAKQAADLHSSSLDQQTLYQ
                     LLSHFDLDGHIEFVRKEYEARMRQMAELLAKHNWPGVKWEEPKGGMFFWLEFPERVDTA
                     ELLKACVEEGVAFVPGVTFYAENPKHNTLRMNFTHNDYEATYSGMEKMNRAIKRVAV"
     CDS             complement(8236..9786)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_122"
                     /sec_met_domain="HMGL-like (E-value: 1.9e-99, bitscore:
                     325.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKIYIFDTTLRDGEQSPGVNLNTQEKLEIAYQLERLGIDRIEAG
                     FPAASPGDLAAVNAVARAVKNATVVGLARSREQDIDAVREALKGAQDPCIHIFIATSPI
                     HRKHKLRMEKEQVLETAERAIRYAKKYFSKIEFSAEDAGRTELDFLCQVTELAVKNGVS
                     VVNIPDTVGYMTPQEFGNIFKTLKENVPDIERIQLSAHCHDDLGMATANALAAILNGAD
                     QIEGTINGIGERAGNTAIEEVALALYTRAEFFQAKTTLNLQEIAKTSRLVSKLTGMVVP
                     GNKAIVGANAFAHESGIHQDGVLKEKTTYEIISPATIGLKDSKLVLGKHSGRHAFREKL
                     IDLGFENLTEEQINAAFGKFKDLADRKKDVSNEDIIALLEEKMVETPEVFALEQLVVSF
                     DSRTGPTATVRLKTAEGFVETKAGGNGSVDAIYRAIDELTKEEVILDDYTIKSVTDGTD
                     ALGDVHVVLRQGDVSAHGRGVSTDILEASARAYVDALNRLIDKRNAPTRSRRDNVTLI"
     CDS             complement(10001..10996)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_123"
                     /sec_met_domain="IlvN (E-value: 5.1e-79, bitscore: 256.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 5.5e-68, bitscore: 220.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVKLYYEKDADLGALKGKTIAVIGYGSQGHAQAQNLRDSGLSVI
                     IGLREGKSAEAARNDGFEVLSVAEATRRADVVQILMPDETQAAVYKNEIEPNLKKGAAL
                     MFSHGFNIHYGQIVPPQDADVLLVAPKSPGHLVRRTYVEGFGVPGLIAVHQNGTGKAFE
                     IGMAYAKGIGCTRAGVIETTFREETETDLFGEQAVLCGGASALVKAGFETLVEAGYAPE
                     MAYFECLHELKLIVDLMYEGGLAAMRNSISNTAEYGDYVTGPRIVTEETKKAMKEVLAD
                     IQSGRFARDFILENQSGRAFLTATRRNEAEHPIEVVGSQLRGLMHWINKK"
     CDS             complement(11255..11740)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_124"
                     /sec_met_domain="ALS_ss_C (E-value: 1.9e-31, bitscore:
                     101.2, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRKHTIAILVNDQPGVLQRVSGLFGRRGFNIESITVGPSEEPGL
                     SRMVIVTTGDDHTLEQIQKQLYKLIDVIKVIDVGSNPMVARELGLIKVSAEPSARPEIL
                     GIVETFRAAVVDISPTSLIVQVVGDSEKIEAMIELLKPYGIRELARTGVTALTRGVK"
     CDS             complement(11737..13482)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_125"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.5e-53, bitscore:
                     172.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAQSATLKSKEELIEKWSKPEVITGSEMLLRSLLLEGVECVFGY
                     PGGAVLYIYDAMYGFDDFKHLLTRHEQGAIHAADGYARSTGKVGVCIATSGPGATNLVT
                     GIATAYMDSVPLVVITGNVATSLIGTDAFQEADIVGITMPITKHSYLVRKVEDLPRIIH
                     EAFHIANTGRKGPVLIDIPKDVSAAKGLFKPVTSVQLRGYNPTVQPNRMQVDKMLRAIE
                     QAERPLLLVGGGAIYSGAHEELYEFVTKTQIPVTTTLLGLGAFPSGHELHIGFPGMHGT
                     WTANTAIQNSDLLINIGARFDDRVTGRLDGFAPNAKIVHIDIDPAEIGKNVPTDIPIVG
                     DVKAVLKVANESAKRADKADAWRAQVQQWKAAKPFKYIDSDKELKPQWVISMIHETTGG
                     DAIVTTDVGQHQMWAAQFYPFNKPRSWVTSGGLGTMGFGFPSAIGAQMGNPDRTVVSIN
                     GDGGMQMCAQELAVCAINNIPVKVAILNNQVLGMVRQWQELIYDNRYSHIDLAGSPDFV
                     KLAEAYGVKAFRATNKEEARRAWTEALNHPGPAVVEFVVRKEENVYPMVTQGSTIDQMI
                     MGDAE"
     CDS             14119..14568
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_126"
                     /sec_met_domain="Acetyltransf_1 (E-value: 2.5e-15,
                     bitscore: 49.8, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRWKNKRDIPDIVRLVRSQLVPISPWFHPRDKRLYDIVSRRIQS
                     GSTLVASQSRSGSPFAFVHFNIRQDRLFIDLLAVDAAFQGRRWGTELMMQAEAHGLGEG
                     CTVAHLFVDEKNERALRFYRRLGYKVARHVKELHCFELFKPLGGD"
ORIGIN
        1 gcgaggtcca gaccacgttc gccgactgcc ccatcgcaaa agacaacaga aataaaatcg
       61 tatagatccc aaaccaggag gcctccggaa acaacagcgg aatcagcccc gtggccaccc
      121 acagcacccg gtggaaaacg gcgaacagca gcagcatgga ccggcggtcg ctccagcgct
      181 gcatgcccgc cgcgataaaa atctggatga tcagcgtaag cgacggaatc gccgccacga
      241 tcccgatctg ctcggaattg aagcccaagt agaggaggaa tgccgtctgc agcggaccgc
      301 ccagcaaatt ggcgatgatc gttgcgggaa tgccctcgcg aaccgaagtc cgcattcccc
      361 tgcgattgct ggaaacgctt gcgcgttccg gacggaaaaa agccgagctc cgcggcagcc
      421 tgaatcttcc ggtcatattc cgacagttcc cccacgatgt aatcaacccg attctactct
      481 ttttccccgg ccagtggcaa gtagataatg aattccgttc cttcgttcag ccggctgtcg
      541 acttgaatcg tgccgccgtg gttgcggata atgcggtagc tgaccgacag gccgagtccg
      601 gttccgtcct gcttggtcgt aaaaaacgga tcgaacagcc gagccatcgt cgaccgctcc
      661 atgcctttgc cgttgtcgcg aatccggatc accgcgtacc ggttttcccg attggccgtc
      721 acctggatca gccctttgcg ttcgtcgccc gaatcctgta tggcatccat cgaatttttc
      781 aaaatattca aaatcacttg cttaatctgc ttgacgtcga tggcgacctg catgaccgga
      841 tcgtagattt cgaagtgcag ctcgcagcct ttcatgttgg cttcgctctc gaacagcaga
      901 atggactcct taagcagcat gccgaccgaa atgtgctgct tcatgggcgc cgaaggcttc
      961 gaggaattga gaaactcaaa gatgatgtcg ttggccctgt cgatctcgga taaaatgatg
     1021 cgggcgtact cctgcttgcc gatcgtctcc aaataaggct tcagaagctg gataaagccc
     1081 cggatcgagg taagcgggtt gcggatttcg tgcgcgatgg aggcggcgat tttgcccagc
     1141 atcgccagtt tgtcgttttg gaatgcggac tgctcgatat gcttgaattc ggaaacgtcc
     1201 ttgacgctga cgagataatc cccgtcgagc tcgtcgatcc gggtaatgct gatcagcaga
     1261 aaacggccgt gcgcatcctg aaactcgccg ttgaacctgc gatagtagac catttccttg
     1321 tacatccgaa ggaaaatcat ccgaatcgat ttgcgaagat aaggatgaaa catgagctgg
     1381 cgcagcgagt ggccgatcaa cgcccggcgg ggagcttgca gcaggcggga catctgcacg
     1441 ttcaagaagc gaagatggcc ttcggaatcg aacagggcga ttccgctgtc catatgctgc
     1501 agcaccgtct cgaatttgct cgggcgttcc tcctgaaggg gcaacgattg aacggccgac
     1561 tccttcagcc gtttcgcgct cgcgtcctcc tctcccgcag cggcttccgg aagcctgacg
     1621 gatgtgagga tttccataag aaacagcagc gatctgtgca tcaaggtcat ccggtcttct
     1681 gcttcggcgt tgtagagaag atccttcacg cttgcctcat gatgactgag tatgtcgtcg
     1741 gaggaaacgc cttgcagttg gtgcatcaat ttcgccttgt ccgtaatggt tccgccttcg
     1801 ctcagcgcaa attcggccaa tgccggaaaa tagcgggatt tccacctttc catgaacgac
     1861 tcctcccgat ccgatccaat atcgacaggt tcgggcagac ctgaaaagca cattgcttaa
     1921 tctttcgatt tgccgtcctg attccgatcc gcgctgcgct tcgaaccgcc gtcatgccgg
     1981 cgggacgggt tccgatcgtg attttcggtc tgccgatttg aagcatttga gatcaggcta
     2041 ccgctgtttt gcccttttat tttgttttcg ttgcgaactt cccggttgcg atgtccgttg
     2101 ttccgctcgc cgccgtcgcc gtagcgccgg ttgccgcttc cggtcttccc gccgcgtgcg
     2161 ccccggttgt cgtcgcctcg ccggtcttcg cggtctttct tcttccctat cttattctcc
     2221 ttgcccgctt tttctgtccg atcccgatga tcccgggtca caagcgcgcc gcccgaagtt
     2281 tgccgagcgt tgctctcctg ttttccgctc ctttcttgat tcgcgtttcg acccccattt
     2341 tcctgttttt cccggtaatt ttgtttcttc cgattttcct gccgctgctg tttcctcaat
     2401 tcatcccgct ttttccggtc ctcttcgact ttatccttca gcgcagccag cagcttgttc
     2461 cattcgtctc tttcgctgcc gtttttcaaa gcggacgagg cggactcgct ctttgtgtcc
     2521 gggttcggct tgttgcccgt aagaacttgt tggacgcctc cccactcgct ggcgatcgtc
     2581 ttcatcgatt catgccgcag cgtctccagc ggcacctcat gcccctggct ttcggccttc
     2641 agccagaagg ccattttccc ggtggatacg ccgcttttct tggcttcctc cctgacttcg
     2701 gcggggaccg ataccgccat aatttccgga gcgttgtccg aagcgccgcc aagccgcttg
     2761 gccgtctgct cgatcgcttt tttcatgctg ccgatgattt cggcttccca ttccgcgtcg
     2821 actttgccta cggccacgct tgccagcacg acttcgccgc ccgagtcgag cagcttccgg
     2881 gaggcaagct cttccgcaag ccgggcggtt acgtcttcga cggtttgccc tttgtattcg
     2941 attgccgcga cgatcggcct cgcatccgca ttcaaggcgc gcagctcgcg cacgtattcc
     3001 ctgctgtcga tgcccatctc gacgctcgga ttgacatcca tcgagacgta agcgacaacg
     3061 gtcggcgtct gaaaccacca cagtcccagc agcaggacga aagcggcaac ggcagaagcg
     3121 cccagaatcg ccgccgttcg gcgtccccca agcaggccgc gccgcgctcc ggtccgtgcc
     3181 cattcgattt cgtcgccgat ccggaaatgg ggcaaccgct tgacccggac gaattggccg
     3241 ccgggcgcca gcacgatcgc ttttctcttt tccaaagaca gaatgacggc ccgattcatg
     3301 gcgtttcacc ctccatgcct ttttccggac tttcgatgta tggttttaaa tgtcggtacg
     3361 gtccgccggc gatcaaagcc gtcgcgatca agtacttgcg gttgcgttcc agcgttttcc
     3421 tggatacttg ctccgcttcg cacagctcct tcagcggaag ctggcgcctc tctttgagca
     3481 tggcgaacaa aacgggattc gccgccagcc tccggccgat tccgagaagc atgtttcgcg
     3541 aatccagatg cttgggggat tgctcgctca aatccgcgaa gctgatgcca aagcccgcaa
     3601 gctcctcggc cagcgccttg atttcttcca gacgcgtttc ccggtcctgg tcctgcgcgt
     3661 aagcctcgag cgcttctttc gcttcgactt gcgacaggag cgacgcgccc tctcccttat
     3721 cgccctccag ggcgctgtac ggcacaagcg acgcgtgccg ctcctctttg cgcgcataat
     3781 cgataagccg cctcgtgatc acctgcgaag caaaggttag aaaccgtccg cccgattgcg
     3841 ccgagtaccc gttgatcgcc tcgtcgaacg caagcagcgc cacgctgaat tcgtcatccc
     3901 gggcgggatc gatgtatcgt ttgcaaaatc ggctagctgt cttgaggata aaaggccgat
     3961 aacgttgaat cagttcgttg cgaagttcct cgttcccttg ctgaatggac gcgaccatcg
     4021 cttccggcgt atcgccctcc ggcgcgccat cgctatcgga acggtgtccg acccattttt
     4081 tccacagtgc gagcagcaaa aactcacccc acaaatatag agttcggatg ctcaagcgat
     4141 tatcggcggg catctccttt ttcgtgcaga aaaacgcccc cgcaccgtgg cgctgccgac
     4201 cagtggggga cgctcaacac tgcctattcg tatcgggtta atacgcgccg ccggacgtcc
     4261 gtttgaaacg aagcttatgg cggcgttgag ccagcatgcc gagccggcgc ttgagctgct
     4321 gctcccattc ggcatcttta agctctttgg cgaacgtaag taaatccaat gccatgtcga
     4381 tctgatactg aacaatgtac agcgggtcct catcctcatg gttgatgcag ttctcgtgga
     4441 gggctttgtc cgattcgtca acgtagtcgt tgaagtcgac ttcggaggcg ccgtcgccgt
     4501 gcgcgtattc agccaaaatc tcgtactcgt tctccaccag gtagtggact tcgacacggt
     4561 ggcataccgg acaaaacaat attggaacgt tatggattct cgttctgaaa tgtttcagcg
     4621 tcccttttgt gccgatcatg ctcgctccgc agcaaaaact catcgttacc cctccccgtt
     4681 ccatgaagat gaatggtgct attcactata ttcttcttgc gtttgcggaa ttcctcccga
     4741 ttggctatag gaccttccgt attatcattt tgccgcattt tgtcggaaaa gtaaaacggt
     4801 cgggctgttt tttatccttt gcagattcgt ctccggccaa acgcccccct taaaaagacg
     4861 cgaaaaggcg catgcatcga gcatgcgcct tcgtaaccgg ttatgtccgg aagctgtctt
     4921 atttggcaac caggtgcttg tcccccggct tccagttgat cgggcacaga ccgccggatt
     4981 gcagcgcttg aagcacgcgg agcgtttcgt ccacgctgcg gcccacatcg ttgtggttga
     5041 cgacctggta tttgataata ccgtccggat cgatgatgaa cagaccgcgc agggctacgc
     5101 cttcttcttc gatcagaacg ccgtaatccc gtgccgtctt cttcgtgatg tcggcggcga
     5161 gcgggaagtt cagcttgcca aggccgtttt cgctcttcgg cgtattgatc caggcgcggt
     5221 ggctgtgaat gctgtcgacg ctgacgccga gaatttccgt gttcagcgcg cggaattgtt
     5281 cagccgcttc ggaaagcgcc acgatttccg tcgggcacac gaacgtgaag tccagcggat
     5341 agaagaagaa taccagccat ttgcctttgt agtcggacaa agaaactttg ccgaagcctt
     5401 gtccgtcgcc aagcgccgtt tcaagggtga aatccggggc ggggagtcct accaaacgtt
     5461 ctgccatgat tcataacctc ctacagttcg gcctgatggc cgggtatttg tctatccttc
     5521 atggtatcat cattgagaag gaaaatcaat atggaacgat tacttgttta gaataaatat
     5581 aaactagcaa atcgtttagc ggatcatttc gccaatgcgg ctacgatcaa atcgcccatc
     5641 tcgctcgtgc tgacggcttt gctcttgtcg acggcaatat cgcttgtgcg atggccggcg
     5701 tcaagcacct ttttgaccgc gtcttcgatc gctttccccg cttccagata gccgaaggtc
     5761 agctggaaca tcagcgccac ggacagaatc gtcgcaatcg ggttggcgat gccctggcct
     5821 gcgatgtccg gagccgaacc gtgcaccggc tcgtacagtc cgaagctgcc ttcgccgagc
     5881 gaagcggagg ccagcatgcc gatggagccg gtcagcattg cggcttcgtc gctgaggatg
     5941 tcgccgaaca tgttctcggt aacgatgacg tcaaagctgg acgggcggcg cagcagctgc
     6001 atcgcgcagt tgtctacgag cacgtgctca agctccacgt ccggatattc cggcgcgatg
     6061 cggttgaccg tctcccgcca gagacgggac gtctcgagca cgttcgcctt gtcgacggaa
     6121 gccaggcgtt ttctgcgttt ccgggcgatc tcgaacgcct ggcgaacgat gcgctcgact
     6181 tcggatacgc tatatacgca cgtatcgacc gcttcctggc cgccttcccc ttcgcggcgg
     6241 aatttgtcgc cgaaatagat gccccccgtc agctcgcgga ccacgatcag gtccgtgcct
     6301 tccagcactt ccggcttcag cgtggatgcg tccttcaggc agtcgaacac gacggcgggc
     6361 cggatgttgg agaacaggcc gagcgccttg cggatgccca gcagcccggt ttccggacga
     6421 agctccttcg gattgttgtc ccatttcgga ccgccgaccg cgccgagcag cacggcgtcc
     6481 gccttttggc aaatttccag cgtttcctgc ggcagcggag tacccttctc gtcgatggcg
     6541 atgccgccga acaagccgta ttccagctca aatttgtagc cgtacagctc ctccgttttt
     6601 ttcagcactt taatcgcttc cgccaccact tccggtccga ttccgtcccc ggagatgacg
     6661 gcaatttttt tcacgtctgc catatgcgcg tttcactccc gattttctta gtgtagcgtt
     6721 gtccgaaact ctccattcat ttgtagcaca tttccgtatc cccggcaaaa tagataaatc
     6781 ctatcgtttc gatagtttca acctataatt tcgcgtgacc gtttcgtccc gagcgcctta
     6841 cgaatgctgg cctgagtgcc tcccacgaat gttgtccgag tgcctcgcgt atgccgcctg
     6901 tttgccgccc gtacgccgcg aagatcgccc ccggcggatc gccgccgggg acgaaacgcg
     6961 gtccggttca gaccgctacg cgtttgatcg cgcgattcat cttctccata ccggaataag
     7021 tggcctcgta atcgttgtgc gtgaagttca tgcgcagcgt gttgtgcttc gggttctcgg
     7081 cgtagaacgt tacgcccggc acaaatgcga ctccctcctc cacgcacgcc ttcagcagct
     7141 ccgccgtatc gaccctctcg gggaattcaa gccagaagaa catgccgcct ttcggctcct
     7201 cccacttgac gccgggccaa ttgtgcttgg cgagcagttc ggccatttgc cgcatccgcg
     7261 cctcgtattc cttccgcacg aactcgatgt gcccgtcgag atcgaaatgc gaaagcagct
     7321 gatacagggt ctgctggtcc agcgagctgg aatgcagatc cgcagcctgc ttcgcttgcg
     7381 tcatgttgcg gatcagcttc gaatcgccga tgacccaacc ggttctaagc gccggagcga
     7441 ccgtcttgga gaacgtgctg gtgtagacga cgcccgaacc ttccggatgc tcgtccagcg
     7501 agaaaatcga cggatacgta acggatccgt cgccgaaact cagctcgccg taaggatcgt
     7561 cctcgagaat cagcgtatcc gtcctgcggc acagctcgag ggtgccgcgg cggcgctgct
     7621 cgctccacgc cttgccggtg gggttcgaga acgtcgggat gacataaagc attttcggtt
     7681 tgtaccgctc aagcttggcg gccagatcgt ccagatcggg accgtcggcg tccccctcga
     7741 ccgaaaccgg cacggcgccg taggaacgga acacttgcag ggcggacaaa tacgtcgggc
     7801 gctcgaccag gatcacgtcg cccggatcga gataaatgcg ggaaagaagg tcgatcgcct
     7861 gctgcgatcc ggtcgtcagc agcatatggt cgggcgtcac ccgcacgccc ttgcgcgcca
     7921 ttcgggcgca cagcgcttcc cgcagcggca ggtacccttc ggtcaagccg tactgaagcg
     7981 ctttgttgcc ctgttccatg acccgttgga acgcctccga caccgccgtc accgggaagt
     8041 gctcttcggc ggggagtccg ccggcgaacg agatgatgga attgccttgc gtcagcttta
     8101 aaatttcacg aaccgccgaa gaagagaagc tccccatctt ggcggaaaac cgatagttca
     8161 ttcggggttc cccatttccg gttcctaaaa tatcgcaaag tccccgaacg cttgaggact
     8221 ccgccgaaaa acggatcaga ttaacgttac gttgtcgcgg cggctgcgcg tgggcgcgtt
     8281 ccgcttgtcg atcagacggt tgagcgcgtc gacgtaagcg cgggcgctcg cttcgagaat
     8341 atcggtgctg acgccgcggc cgtgcgcgct tacatcgccc tgccgcagga ccacgtgaac
     8401 gtcgccaagc gcgtccgtgc cgtcggtgac cgatttgatc gtgtagtcgt ccagtataac
     8461 ttcttctttc gtcagctcgt cgatcgcgcg gtaaatggcg tcgaccgagc cgttgccgcc
     8521 cgctttcgtc tcgacaaagc cttcggcggt cttcagccgg acggtagccg tcgggcccgt
     8581 gcggctgtcg aacgagacga caagctgctc cagggcgaac acttccggcg tctcgaccat
     8641 cttctcttcc agcagcgcga tgatatcctc gttgctgacg tccttcttgc ggtcggccaa
     8701 gtccttgaac ttgccgaacg cggcgttgat ctgctcttcc gtcaagttct cgaagccgag
     8761 atcgatcagc ttctcccgga acgcatggcg tcccgaatgc ttgccgagca cgagcttgct
     8821 gtccttgagg ccgatcgtcg ccggggagat gatttcgtac gtcgtcttct ccttcagcac
     8881 gccgtcctga tgaatgccgg attcgtgcgc gaacgcgttg gcgccgacaa tcgccttgtt
     8941 gccgggaacg accatgcccg tcagcttgct gaccagcctg cttgtcttgg cgatctcctg
     9001 caggttaagt gttgtcttcg cctggaaaaa ttccgcccgc gtataaaggg ccagcgccac
     9061 ttcctcgatc gccgtgttgc ccgcacgttc gccgatgccg ttgatcgtgc cttcgatctg
     9121 gtcggccccg ttcaagatgg ccgcaagcgc attcgccgtc gccatgccga gatcgtcgtg
     9181 gcagtgcgcg gacagctgga tgcgctcgat gtccggcacg ttctccttca aggttttgaa
     9241 gatgtttccg aattcctgcg gcgtcatgta gccgacggta tccgggatgt tcacgaccga
     9301 aacgccgttc ttgacggcaa gctcggtgac ctggcacagg aaatccagct ccgtccgtcc
     9361 cgcatcctcg gccgagaact cgattttgct gaaatatttt ttggcgtacc ggatcgcccg
     9421 ttcggccgtc tccagcacct gctccttctc catccgcagc ttgtgcttgc ggtgaatcgg
     9481 ggatgtcgcg ataaaaatat gaatgcaagg gtcctgcgcg cccttcagcg cttcgcgcac
     9541 cgcgtcgatg tcctgctcgc gcgaacgcgc aaggccgacg acggtggcgt tcttcaccgc
     9601 gcgcgcgacc gcgttgaccg cggccaggtc gccgggagaa gcggccggaa agcccgcctc
     9661 gatccggtcg attccgaggc gttccaactg atacgcgatt tcgagtttct cttgggtgtt
     9721 caggttgaca ccgggggact gctccccgtc gcgcagcgtc gtatcaaaaa tgtatatttt
     9781 ccgcatatgg cagcttgatg cccgcacctc ctgaagcagc taatgaagtt cagaccgccc
     9841 tgctgctggt cttggttcga ttataacata atcggaagcg ccttctagcg aaatccgcaa
     9901 gttcggacga gatttgccgg gaatttcgca acccgccgaa tcttgataaa caaccccggc
     9961 tttggccggg gttgtccgat tgcgcgttgg ggcgccggaa ttacttcttg ttgatccagt
    10021 gcatcaggcc gcgcagttgg gagccgacca cttcgatcgg atgctcggct tcgttgcggc
    10081 gggtagccgt aaggaaggcg cgcccggatt ggttttccag gataaagtcg cgtgcgaagc
    10141 ggccggattg gatgtcggcg agcacttctt tcatcgcttt tttcgtttct tcggttacga
    10201 tgcgcggacc ggtcacgtaa tcgccgtatt cggccgtgtt ggagatcgag ttgcgcatcg
    10261 cggcgagacc gccttcatac atgaggtcga cgatcagctt cagctcgtgc aggcactcga
    10321 agtaggccat ttccggagcg tagcccgctt cgacgagcgt ttcgaaaccg gctttgacga
    10381 gcgcgcttgc gccgccgcac agaacggcct gttcgccgaa caggtcggtt tccgtttctt
    10441 cgcggaacgt cgtttcgata acgcccgcac gggtacagcc gatgcctttc gcgtaagcca
    10501 tgccgatttc aaacgctttg ccggtgccgt tttggtgaac ggcgatcaat ccgggaacgc
    10561 cgaagccttc tacgtacgtg cggcgaacca gatggcccgg ggatttcgga gcgacgagca
    10621 gaacgtcggc gtcttgaggc ggaacgattt ggccgtaatg gatgttgaag ccatgggaga
    10681 acatgagtgc ggcgcctttt ttcaggttcg gctcgatttc gtttttgtag acggcggctt
    10741 gcgtttcatc gggcatcagg atttgcacga catccgccct gcgggtcgct tcggcaacgg
    10801 acagcacttc gaagccgtcg ttgcgggccg cttccgcgga tttgccctcg cgcaggccga
    10861 tgatgacgga caggccgctg tcgcgcaggt tttgggcttg agcgtggcct tggctgccgt
    10921 agccgataac ggcgatcgtt ttgcctttca gagcgccgag atcggcgtct ttttcgtagt
    10981 acaatttaac tgccattgga tgtgtttcct ccttctttat gaaaaaacta tataggcaac
    11041 cctcatgaaa cgggcgtccc aagagagaac cgggccgcaa gttttcgatc cgccacaagc
    11101 cggcgcccgc cggaacgtct aggcggcgcc ctccgcatcg gaaggccgca ggacaagcct
    11161 cgggcgcggg acgatcggcc cgctttgcgc ggttctctcc tcgaacaccc gctcccgggg
    11221 gaagcgagcg gataggatga aggcaataag cccgttactt cacgccgcgg gtcaaggcgg
    11281 tgacgccggt gcgggccaac tcgcgaatgc cgtacggctt gagcagctcg atcatcgcct
    11341 cgatcttctc ggaatcgccg accacctgca cgatcaggct ggtcggactg atatcgacga
    11401 cggcggcgcg aaacgtctcg acgatgccca aaatttcggg ccgggcggac ggctcggcgg
    11461 aaaccttgat cagtccgagc tcgcgggcga ccatcggatt ggagccgacg tcgatcacct
    11521 tgatgacgtc gatgagtttg tacaattgtt tctggatctg ttcgagcgtg tggtcatcgc
    11581 ctgtcgtcac gatgaccatg cgggacaatc ccggttcttc cgaagggccg acggtgatgc
    11641 tctcgatatt gaagccgcgt cttccgaaca atccggatac ccgttgcaga acgcccggct
    11701 ggtcgttgac gagaatcgcg atcgtatgtt tccggttcat tccgcatccc ccatgatcat
    11761 ttggtcaatc gtactgccct gcgtaaccat cggatagacg ttctcttcct tgcggaccac
    11821 gaattcgacg accgccggac ccggatggtt cagcgcttcg gtccaggcgc ggcgcgcttc
    11881 ctccttgttc gtcgcgcgga acgccttgac gccgtacgct tccgccagct tgacaaagtc
    11941 cgggctgccg gcaagatcga tgtggctgta gcggttgtcg taaatcagct cctgccactg
    12001 gcgaaccatg ccgagcacct ggttgttcaa aatcgcgact ttgaccggaa tattgttaat
    12061 cgcgcacacc gcaagctcct gggcgcacat ctgcatgccg ccgtcgccgt tgatggagac
    12121 gaccgtccgg tccgggttcc ccatctgcgc gccgatggcc gacgggaagc cgaagcccat
    12181 cgtgccgagt ccgccggacg tgacccagga acgaggcttg ttgaacggat aaaattgcgc
    12241 cgcccacatt tgatgctgtc cgacgtcggt cgtcacgatc gcgtctccgc ccgtcgtctc
    12301 gtgaatcatc gaaatgaccc actgcggctt caattccttg tcggaatcga tatatttgaa
    12361 cggcttggcc gccttccact gctggacctg cgccctccag gcatccgcct tgtccgcccg
    12421 tttggcgctt tcgttggcga ctttgagcac ggctttgaca tcgccgacga tcggaatgtc
    12481 cgtcggcacg tttttgccga tttccgcggg gtcgatgtcg atatggacga tcttcgcgtt
    12541 cggcgcaaag ccgtccagcc ggcccgtaac gcggtcgtca aaccgcgcgc cgatgttgat
    12601 cagcaggtcc gagttctgga tcgcggtgtt ggccgtccag gtgccgtgca tgcccgggaa
    12661 gccgatatgc agttcgtgtc cgctcgggaa cgcgcccaga ccgagcaagg tcgtcgtgac
    12721 cggaatctgc gtcttcgtta cgaattcgta cagttcctcg tgcgcgcccg aatagatggc
    12781 gccgccgccg acaaggagca gcgggcgttc ggcctgctcg atggcccgca gcattttgtc
    12841 cacctgcatc cggttcggct gcacggtcgg attgtaaccg cgaagctgaa cggacgttac
    12901 cggcttaaac agcccctttg ccgccgatac gtccttcgga atatcgatca agaccggacc
    12961 tttgcggccg gtgttggcaa tatggaacgc ctcgtgaatg atacggggca gatcctcgac
    13021 cttgcgcacc aaatagctgt gcttggtgat cggcatcgtg atcccgacga tatcggcttc
    13081 ctggaaagcg tccgtgccga tcaggctcgt cgccacgttg ccggtgatga cgacgagcgg
    13141 caccgaatcc atataggccg ttgcgatgcc ggtgaccagg ttggtcgctc cgggacccga
    13201 ggtggcgatg cagacgccga ccttgcccgt gcttctggcg taaccgtcgg ccgcgtgaat
    13261 cgccccttgc tcgtgacggg tcagcagatg tttaaagtcg tcgaagccgt acatggcatc
    13321 gtaaatatag agaacggcgc cgccgggata gccgaagacg cattcaacgc cctccaacag
    13381 caaacttctc agcagcattt ccgaaccggt aatgacttcc ggtttgctcc atttttcaat
    13441 cagctcttct ttggatttca gcgtggcact ttgcgcgctc atccgtcatc ctcctttcgc
    13501 aatttcggat cgttaggcca aacggtacgc cgctcgcaaa aaaacgctcg tccgtttcgg
    13561 cgacaacgac tcggaaaaag gtcgaaagac cgtttttccg aatcggaaat caaaaaaacc
    13621 ttccgcccct gaacattcaa gcagaacgtt ctgggacgaa aggttgttcc ttccgcggta
    13681 ccacccggat tcgccgcgca tctcgcgatg acggcctcgt cgagtatggg cgccaaacct
    13741 ttagcgctaa aggggcaagc cgcatacttc gggcgcgata acgtgcgcca ttccgattca
    13801 ccctacagcg ccgacaagcg gcggttcaag cgaacagctc caaggagacc cagcgtacag
    13861 ggattaaggc atcggtctca gcaattccga cgctctctga gcttaagagc cctcgcgctt
    13921 cttcctcttc acggccattg cgttaaatgt taattcgata cagctttgat tatattcttt
    13981 gctcaagcgt tcgtcaatac acgtttcgaa ttcgaaaagc gaaataggcg gaggtccgcc
    14041 ggaaggggag gatcatacga tgtagaagcg gccgtttcga ttggcaagtc gtcttcggcg
    14101 gcccaaagga ggtgcgccat gatccggtgg aaaaacaagc gcgacatacc cgacatcgtt
    14161 cgccttgtcc gttcgcagct cgtgccgatc tcgccgtggt tccatcctcg cgacaaaagg
    14221 ctgtacgaca tcgtttcccg gcgaatccaa agcggttcca cgctcgtcgc gtcgcaaagc
    14281 cgcagcggct ccccgtttgc cttcgtccat ttcaatatcc gccaagaccg gctgtttatc
    14341 gatctgcttg cggtcgacgc cgcgttccag ggaaggcgct ggggcacgga gcttatgatg
    14401 caagccgagg cgcatggcct gggcgaaggc tgcacggtcg ctcatctgtt tgtcgacgaa
    14461 aagaacgaac gcgctcttcg tttttaccgg cgtctcggct acaaagtcgc aaggcacgta
    14521 aaagagctgc actgtttcga gctcttcaag ccgttgggcg gtgattgacg gctcaaaccg
    14581 aaaaaggctg cgcggagccg tctccaaaac gccgacggct tgggccggac gattcggaaa
    14641 gagaggcgag ggcttgtcct tttcttttcc gatcgctcag atcgagtagg agggggcggc
    14701 taacccccgt cctctcacaa cacctagcat gcgggtccgc actaggcgtt tccaaaaggt
    14761 tgacaaagtt ccagataacg agaaagcaaa cttttcagcc cttttgcttc ccaataggaa
    14821 gttggaaggg cgttgtttat ggttcgggac atttcccaag gacctcgtct agaattggcc
    14881 atcatgaaga ccatccaatc gggcatgcca agcgcccgga gttcgcggat gcgggttcgt
    14941 acccgtttcc actgtttcca ttggcacatg cgaagcct
//
