LOCUS       c00170_NZ_PEMR..       13317 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_PEMR01000177.1 Thermus scotoductus strain 6_S6
            NODE_25_length_21242_cov_49.0245_ID_49, whole genome shotgun
            sequence.
ACCESSION   NZ_PEMR01000177
VERSION     NZ_PEMR01000177
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:42:38
            Original ID  :: NZ_PEMR01000177.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 7925
            Orig. end    :: 21242
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13317
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[17925:20366]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12441
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13317
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13317
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             58..732
                     /locus_tag="ctg170_10"
                     /transl_table=11
                     /translation="MTRYRIATRPYLPYPGERLARRKGLGGEFYELRPYAPGDEIRRVH
                     WRAYGKTGRLYTRLETTPERSRFRIYLDESESMRLFGKLAYGEEVARLLLGIARQEDAL
                     ARLERGRPEALRPGRGTLVFITDGLDPLPWPRILPKRVVLVQVLAPLELAPPLEEAFLK
                     DVETGETLPVGPEEVRAYQKALEGHLKALRLLALLRGRYALLRVGEPPLPALLRQGVLE
                     PI"
     CDS             complement(764..2017)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SBP_bac_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1044:Bacterial extracellular solute-binding protein
                     (Score: 90.9; E-value: 4.8e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg170_11"
                     /sec_met_domain="SBP_bac_1 (E-value: 2e-28, bitscore: 90.9,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKALLLAAVLGLALAQQAKPEEVIKEQCAKAKVVAELWHGFTGG
                     APKAALENLVVEFNKTQQGRCVRPVPQGGYRDLSTKIKAAFAAGKVPAMAQAYENNIAL
                     YLEAKALLPIESLGVKLQGVNLAFLNAVRFGGVVYGVPFNKSIQVLYYNKDLLKKHGAK
                     VPATLEEFVALSKKLSQAEGGPVYWFQPDASTFAYFFFNLGGSYLKNGKLVLNSKEAVE
                     ALTLLQNGVKEGWAKAITSGYINQNLGSGPYAFSVDTSAGYTYYRQGAKFDLGVATLPG
                     RTKGQPGFGLVQGTNLVVFRQASKEEQAVAKDFLQFVLSPRAQAVFATATGYVPVTEGA
                     LKDAVYQTYATENPHFATIVRQSRYAKFEPALAEWEQIRFDILGQAIKEAILNKADPKS
                     VLDKAQKLAEDLLSGKIR"
     CDS             complement(2071..3264)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 65; E-value: 2.4e-20)"
                     /gene_kind="transport"
                     /locus_tag="ctg170_12"
                     /sec_met_domain="BPD_transp_1 (E-value: 9.8e-21, bitscore:
                     65.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFRPGVLFVHLLLLLGGLVMAFPFYWMLATSLKSPQEALQAKPV
                     WVPERMKPANWLKAAQLGDSPLWGGLAPGRSVELVFPGREGHPPRALVPRTPGAFFDPR
                     ADGTRVEVVYREGAWRVRLTNATEEAFRFLPLVVLWPKEVPLAAPLPPDAIRSQGEYWR
                     LEWVNAVPGALGYVLHNYLEAWHAAPWGRYFFNSFFTALTQVAVGLFLGALAAFALARI
                     PFPGKEAVFVLILATMMVPGEVLLIPNYVLLARLGWLDTYYALIVPWLASVFGIFLLRQ
                     FYLSLPQDLFDAARIDGAGYLTQLFRIALPLSLPGLVSYGIFTFLGAYNALLWPLIVTQ
                     SPEMRTVQLGLQAFVSEAGSDYGALMAASTFVILPVILGYFFAQRQFIQGIARSGLK"
     CDS             complement(3254..4210)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg170_13"
                     /sec_met_domain="BPD_transp_1 (E-value: 9.9e-13, bitscore:
                     38.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LFGRGLRQKEQAALYGWALVWPALALLLVWHVFPTFYAFYLSLFE
                     RVNFLRPAAFAGLENYRILLQDPLFWKALGNTFWYVVFTVPVGLLLATGVAILLNTQVA
                     FLGFYRTLYFLPYITALTAAAAVWRWIYHPEFGFLNWLLGTPGLDWLNTPKGVFALLLE
                     PLGVQPPGFWAGPSLAFVAIMVMSVWHFLGYQVVILLAGLQAIPKEYYEAAELDGASFG
                     QKHRLITWPLLSPTTFFLFTLGLIGAFQVFTQVYVLTPTGGVLQDTLTLAFYLYNKGFR
                     DSDFSYASAIAMVTFLLILVLTLIQRRVLERRVNYEI"
     CDS             4476..5030
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg170_14"
                     /sec_met_domain="Peptidase_M22 (E-value: 5.4e-18, bitscore:
                     56.3, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VWTLTLDTATPYLSLGLFRGEEGVGRVVRLGRKHEEALFGLLDDL
                     LREVGVEREEIGTLVLGEGPGSYTGLRIALAAGIGIALAHRAKVFGVSSLLAACWPFLE
                     EGGPPLTALFTARNGLYYGATYARREGKPLVLEPPRKLKAPEISRAQLQGSHLLLDAPP
                     DPRALYELLPFARDGVEPLYL"
     CDS             complement(5041..5721)
                     /locus_tag="ctg170_15"
                     /transl_table=11
                     /translation="MRFSAWVIFMSLRVLGVNASARTDGFTAELLDEVLEAARQQGATT
                     ERLDLVRYPFPFCVGNYSQDPTSCGPDTCVQGPWDGFGKIADKLVQADAVVFATPVYWF
                     SVSARMKALLERMTSMENQGLLNLGKPMVLLAVAEEEGASQALSQMLLPLSYMGFVLVP
                     LGLVYAHHRGAVSLKGNTELMEDARIAGENLVLMAEKLRGTAFREPLPSYQYRLPRLPG
                     VAAD"
     CDS             complement(5779..5943)
                     /locus_tag="ctg170_16"
                     /transl_table=11
                     /translation="VALPLVDCLCPPRVGVGLHFVSLDRWKSPLGCTYVLAWPLEGPVM
                     ELKGYPVLA"
     CDS             6014..6160
                     /locus_tag="ctg170_17"
                     /transl_table=11
                     /translation="MALWLVRAGKSGETEAFCLESYERLPEELKAELPLKRIWILVEDE
                     ENA"
     CDS             6157..6912
                     /locus_tag="ctg170_18"
                     /transl_table=11
                     /translation="MTDTHAHLDFLEEAELEDAKAHFPELRAILTLGVDPTRWERTLAL
                     AQENVYAAVGLHPTSAHLLSPEVEEALRYYARHPRVRAVGESGLDYYWTPETKPAQLKA
                     LEFQATLAEEFGLPLVLHVRSKDGQAEEDLAAWLLAHRPQRVVLHAFGGHPALEAAGLE
                     VGAYFSLAGPLTYKKNQALREAAQRLPLDRLLVETDTPFLPPEPHRGKRNLPHYVRHTL
                     NRLAEVRGMTLEEMESITDQNAETCFRWT"
     CDS             6969..8267
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg170_19"
                     /sec_met_domain="PLDc_2 (E-value: 2.4e-25, bitscore: 79.7,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKLFLLLFLLLTALAAPKLVVEPDDGVKPLLDLIASAREEILVK
                     MYLWTPSRLDVVDALGEAVARGVKVKVLLEREPSGGRVDLTVFQALKERGVDVKLTTPF
                     RFVFVHEKSLVVDRKLAWVGTMNLTGSSFTANREYALILDDPRQVAEVVKVFEADWEGK
                     RLDLSQALLVWAPSRILGGVKEGNARETLLALIRGAKREVFLEHQAMADPEVVAALQEA
                     LARGIRVRLVGSPQEPGDTYFLAGAEELRRAGADLRFLPDPYVHAKALVVDGEVALVGS
                     LNLSANSINANRELAVRFTRKEAPEAFARLLSVMERDFQAGLTENTFALPPLEGIIPWQ
                     EAPRYFGRIATVEGLIQQVEDRGTVAFLRFGPGESDLRLVVFPRNYGLFQQPFPQSYLG
                     QKVRAKGRIVLYAGYYEIILEDPSALEVLDGSP"
     CDS             8254..8553
                     /locus_tag="ctg170_20"
                     /transl_table=11
                     /translation="MEALKALGYEISPIEGGFYGEKRRGGVVYQVFYSEEGDLRLRRLR
                     FLKEEARPLSLAGVEGEWAARYQLEENFFAVVPQEDLPSLVLAFERLDLGAETP"
     CDS             8667..9935
                     /locus_tag="ctg170_21"
                     /transl_table=11
                     /translation="MRVLVRDLKKHVGEEVELLGFLHWRRDLGRIQFLLLRDRSGIVQV
                     VTGGQKLPLPESSLRVRGQVVENPKAPGGLEVQAKEIEILSPALEPTPVEIPKEEWRAS
                     PDTLLEYRYVTLRGEKARAPLRVQAALVRGFRRYLDRQDFTEIFTPKVVRAGAEGGSGL
                     FGVDYFEYRAYLAQSPQLYKQIMVGVFERVYEVAPVWRMEEHNTSRHLNEYLSLDVEMG
                     FIEGEEDLMRLEENLLQEMLEEALSSAGNEIRLLEAEWPSFPKEIPRLTHAEARRILKE
                     ELGYPVGQDLSEEAERLLGQYAKERWGSDWLFITHYPRSLRPFYTYPEENGTTRSFDLL
                     FRGLEITSGGQRIHRYPDLVESLKAKGMDPEAFQGYLEVFKYGMPPHGGFAIGAERLTQ
                     KLLGLPNVRYARAFPRDRHRLTP"
     CDS             complement(10001..10699)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 122.3; E-value: 2.8e-38)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg170_22"
                     /sec_met_domain="Fer4_10 (E-value: 1.9e-13, bitscore: 41.2,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.1e-38, bitscore: 122.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.9e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVTLKILRFDPAKDQKPTWHTYQVEAEPWDRVLDLLHKVKWDQD
                     GTLAFRRSCGHGICGSDAMLINGRNRLACKTLVKDLGSVITVEPIRGLPVEKDLIVDME
                     PFFAAYRAVKPYLINDEPPPARERLQSPEERARYEEATRCILCAACTSSCPVYWVNGHY
                     IGPAAIVQAHRFLFDSRDRGKRERFKALGSGSGVWRCRTAYNCTEACPRDIPVTQLIEE
                     VKRAILFDRF"
     CDS             complement(10708..12441)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 382.6; E-value:
                     8.7e-117)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg170_23"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.5e-117,
                     bitscore: 382.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.4e-46,
                     bitscore: 147.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHRHEVIVVGAGGAGLATALYAAREGADVAVVSKLYPTRSHTGA
                     AQGGIGAALGNVEEDHWEWHMFDTVKGGDYLTDQDAAEVFAKEVIEAVIELEHMGLPFD
                     RLPNGKIAQRRFGGHTKDWGKAPVHRAAHAADRTGHMILQTLYQQCVKHNITFYNEFHV
                     TDVIVEDGVAKGLVAYELATGELHLFQAKAIVIASGGFGRIYKVTSNAYTLTGDLQAIL
                     YRKGLPLEDMEFYQFHPTGLYPLGILLTEGARGEGGILRNALGERFMERYAPTIKDLAP
                     RDMVSRAMYLEVREGRGVGPKKDHVLLDLTHLPPEVIEKKLPDITEFSRIYLGVDPLKE
                     PVPVMPTAHYAMGGIPTTLWGQVIRDENNTVVPGLYAAGEAACVSLHGANRLGTNSLGD
                     LVVFGRRAGIHAARFAKDADYHELTEEHLRESRERIERIKNSTGKEKVAALRAELQQTM
                     MDNASVFRTGELLAKQVEILKELMDRYRNISIDDKGDAYNTELVEALELGYLLEVSEAL
                     VHSALNRTESRGAHAREDYPERDDQNWLKHTLAYKVADGKVTFRYKPVVLGRFEPKART
                     Y"
     CDS             complement(12443..12844)
                     /locus_tag="ctg170_24"
                     /transl_table=11
                     /translation="VVMAIKSRRYEEAKLEASTNLELYWWVFMRISGVVLVFLLIGHMW
                     MNAILIDLNQIDYNYVAKRLSQTTWKVYDWLILALALLHGGNGLRYVLDDWVRHPVRRF
                     WTKVVVYSLIAFLFFLGSLSLFNFDFGVK"
     CDS             complement(12828..13193)
                     /locus_tag="ctg170_25"
                     /transl_table=11
                     /translation="MYRGREGQWAFYLHRISGLGILVFLMLHVANIASAMWGPEVSNAL
                     MKFYHQPVFQIGLLLLIAGVLYHGFNGLRIILMDFTAWGVRYQRQLWYGVWVLFVIFYL
                     PFLLKIGGGILGGGHGD"
ORIGIN
        1 ggaggaagtc atcgaacccc tgcccccggt gggggtctgc accttctgcc ggacggcatg
       61 acccgctacc gcatcgccac ccggccctac cttccctacc cgggagagcg cctggcccgc
      121 aggaagggcc tgggaggcga gttttacgag ctccgcccct atgcccctgg ggacgaaata
      181 aggcgggtcc actggcgggc ttacgggaag acgggaaggc tctacacccg cctggaaacc
      241 acacccgagc gaagccgctt ccgcatctac ctggacgaaa gcgaaagcat gcgccttttc
      301 ggcaagctgg cctacgggga ggaggtggcg aggctcctcc tggggatcgc ccgccaggag
      361 gacgccctgg cccggctgga acggggcaga ccggaagccc ttcgcccggg ccggggcacc
      421 ctggtcttca tcaccgatgg gctagacccc ttgccctggc ccaggatcct tccgaaacgg
      481 gtggtcttgg tccaggtcct ggcgcccctg gagctggccc cgcccctcga ggaagccttc
      541 ctcaaggacg tggaaaccgg ggaaaccctc cccgtgggcc cggaggaggt aagggcatac
      601 caaaaggccc tcgaggggca cctaaaagcc ctccgcctcc tcgcccttct tcgggggcgg
      661 tacgccctct taagggtggg ggagcctccc ctccccgccc tcctgcgcca aggggttttg
      721 gagcccatct agggcaatcc cggggcgggg aggggccgtg gccctaacgg atcttgccgg
      781 aaaggaggtc ctcggccagc ttctgggcct tgtccaggac cgacttggga tccgccttgt
      841 tcaaaatggc ctccttgatg gcctggccca ggatgtcaaa gcggatctgc tcccactccg
      901 ccaaagccgg ctcaaacttg gcgtagcggc tttggcgcac gatggtggcg aagtgggggt
      961 tttcggtagc gtaggtctgg tagaccgcat ccttcagggc tccctcggtc accggcacgt
     1021 acccggtggc ggtggcgaag accgcctggg ccctggggga gaggacaaac tgcaggaagt
     1081 ccttggccac cgcctgttcc tccttgctgg cctggcggaa gaccaccagg ttggtgccct
     1141 ggactagacc aaacccaggc tggcccttgg tgcggcccgg cagggtggcc acccctaggt
     1201 caaacttggc tccctggcgg tagtaggtgt agccggcaga ggtatccacg ctgaaggcgt
     1261 aggggccgga gcccaggttc tggttgatgt acccggaggt gatggccttg gcccacccct
     1321 ccttcacccc gttttgcagg agggtgaggg cctccaccgc ctccttggag ttcaggacca
     1381 gcttgccgtt tttcaggtag ctccccccca ggttgaagaa gaagtaggcg aaggtggagg
     1441 catccggctg gaaccagtag acaggtcctc cttccgcctg ggaaagcttc ttgcttaagg
     1501 ccacgaactc ctcgagggta gctggcacct tggccccgtg cttcttcagg aggtccttgt
     1561 tgtagtagag gacctggatg ctcttgttga agggcacccc gtacaccacc cccccgaagc
     1621 gcacggcgtt caggaaagcc aggttcaccc cctggagctt cacccccaag gactcaatgg
     1681 gcagtagggc cttggcctcg aggtacaggg cgatgttgtt ctcgtaggcc tgggccatgg
     1741 ccggcacctt ccccgcggcg aaggccgcct tgatcttggt ggaaaggtcc cggtaccccc
     1801 cttggggcac gggacgcacg caccggccct gctgggtctt gttgaactcc accaccaggt
     1861 tctccaaggc ggccttgggg gccccgccgg tgaagccatg ccaaagctcc gccaccacct
     1921 tggccttggc gcactgctcc ttgataacct cctcgggctt ggcctgctgg gcaagggcta
     1981 gccccaaaac cgccgccaac aaaagcgctt ttcgcatacc caaaacctcc agactaagta
     2041 tatccctcct ggtgtcaagc caaggtcagg ctatttgagc cccgagcggg cgatgccctg
     2101 gatgaactgg cgctgggcga agaagtaccc caggatgacg gggaggatca cgaaggtgct
     2161 ggccgccatc agggccccgt agtccgaccc cgcctcggag acaaaggcct gcaggcccag
     2221 ctggaccgtg cgcatctccg ggctctgggt aacgatgagg ggccaaagga gggcattgta
     2281 ggcccccagg aaggtgaaga tcccgtagga caccaatccc ggaaggctta agggcaaggc
     2341 gatgcggaaa agctgggtca ggtacccggc cccgtctatg cgggccgcat caaagaggtc
     2401 ctggggcaag gagaggtaaa actgcctaag gaggaagatg ccaaacaccg aggccagcca
     2461 gggcacgata agggcgtagt aggtgtccag ccagcccagc ctggccagaa gcacgtagtt
     2521 ggggatgagg agcacctccc ccggcaccat catggtggcg aggatgagca cgaacaccgc
     2581 ctccttgccg ggaaagggaa tgcgggccag ggcaaaggcc gccagggccc ccaggaaaag
     2641 ccccaccgcc acctgggtca aggcggtgaa gaagctgttg aaaaagtagc ggccccaggg
     2701 agccgcatgc caggcctcga ggtagttgtg gagcacgtag cccaaggccc cgggcaccgc
     2761 attcacccac tccagccgcc agtactcccc ctgggagcgg atggcgtcgg ggggcaaggg
     2821 tgccgccaga gggacttcct tgggccagag caccaccagg ggcaaaaagc ggaaggcttc
     2881 ctccgtggcg ttggtcagcc gcacccgcca agccccttcc cgatacacca cctccacccg
     2941 agtgccatcc gcccgagggt caaagaaggc cccgggggta cggggtacca aggccctggg
     3001 gggatgccct tccctcccag ggaaaaccaa ctccacgctc cttccaggtg ccaagccccc
     3061 ccataggggg ctatccccca gctgggccgc cttgagccag ttcgccggct tcatgcgctc
     3121 gggaacccag acgggcttgg cctgcagggc ctcctggggg cttttcaggc tggtggccag
     3181 catccagtag aaggggaagg ccatgacgag cccccccagg aggaggagca ggtgcacgaa
     3241 caggacaccg ggcctaaatc tcatagttca cccgcctctc caacacccgc ctttgaatca
     3301 gggtgaggac caggatgagg agaaaggtca ccatggcgat ggcactggcg taggagaaat
     3361 ccgagtcgcg gaaacccttg ttgtagaggt agaaagccag ggtaagggta tcctgcaaca
     3421 ccccgcccgt gggggtcagg acgtaaacct gggtgaacac ctggaaggcc ccgatgagcc
     3481 ccagggtgaa gagaaagaag gtggtggggg aaagaagcgg ccaggtgatg agccggtgct
     3541 tctgcccaaa gctcgcccca tccagctccg ccgcctcgta atactccttg ggaatggcct
     3601 gaagcccggc caggaggatc accacctggt atcccagaaa gtgccacacg ctcatgacca
     3661 tgatggccac aaaggccagg ctgggccccg cccaaaaacc cgggggctga actcccaggg
     3721 gctcgaggag cagggcgaag acacccttag gcgtgttcag ccagtcgaga cccggggtac
     3781 caagaagcca gttgagaaaa ccgaactccg ggtggtagat ccagcgccac accgccgccg
     3841 ccgccgtgag ggcggtgatg taggggagaa agtaaagggt gcggtagaac cccaggaagg
     3901 ccacctgggt gttcaggagg atggccaccc ctgtggccag gagaaggccc accggcacgg
     3961 taaagaccac gtaccagaag gtgttcccca aggccttcca gaaaagagga tcctggagga
     4021 gaatacggta gttctccaag ccagcgaagg ccgcggggcg caggaagtta acccgttcaa
     4081 agaggctcag gtaaaaggcg taaaaggtgg ggaaaacatg ccagaccaga aggagggcta
     4141 aggccggcca aaccaaggcc cagccgtaga gggctgcctg ctccttttgc ctcaggcccc
     4201 ggccaaacaa gagggcgaac aagagaggag ccagaaaggc caggggtggg aaccagtacg
     4261 caaaaagccc aagccccaaa agggcatggt gccgaccgaa acgaagcccc cacaggacga
     4321 gaagggcgta aagcccaagc cccgccccca cccaggccca cgggagaaag ccgagccgga
     4381 aggcgtacac acccagggca aggagcgccc ccaaggacag aagggcatgg agaggaaagg
     4441 tccgcatccc gtgtcggagt atataggatg gaagggtgtg gaccctcacc ctggacaccg
     4501 ccactcccta cctttccttg ggccttttcc gcggggaaga gggagtgggc cgggtggtgc
     4561 ggctgggccg taagcacgag gaagccctgt tcggcttact ggacgacctc ttaagggaag
     4621 tgggcgtgga gcgggaggag atcggcaccc tggtcctggg ggagggcccg ggttcctaca
     4681 cgggccttcg catcgctttg gcagcaggga taggcatcgc tttagcccat agagccaagg
     4741 tgtttggggt aagctccctc cttgccgcct gctggccctt cttggaggaa ggtgggcctc
     4801 ccctaaccgc ccttttcacc gccagaaacg ggctctacta tggggccacc tatgccaggc
     4861 gtgaggggaa gccgcttgta ctcgagcctc ccaggaagct caaagcccca gagatctcaa
     4921 gggcccagct ccagggtagc caccttctcc tggacgcgcc cccagacccc agggctcttt
     4981 acgagcttct gccctttgcc agggatgggg tggagccctt gtacctttga agcgtccctg
     5041 ctagtccgcc gccactcctg gcagcctggg cagacggtac tggtaactgg gaaggggttc
     5101 ccggaaagcg gttcccctaa gcttttccgc catcagcacc aggttctccc cggcaatgcg
     5161 ggcatcctcc atgagctcgg tgttcccctt gaggctcacg gcaccccggt gatgggcgta
     5221 gaccaacccc aggggcacca ggacaaaccc catgtaggaa aggggcagga gcatctggga
     5281 aagcgcctgg ctggcccctt cctcctcggc taccgccaac aggaccatgg gcttgcccag
     5341 gtttaagagg ccctggttct ccatggaggt catgcgctcc aaaagggcct tcatccgggc
     5401 ggaaacgcta aaccagtaga ccggcgtggc gaaaaccacc gcgtccgcct ggacgagctt
     5461 gtccgctatc ttaccgaagc catcccaggg tccctgcacg caggtgtccg ggccgcagga
     5521 agtagggtct tgggagtagt tccccacgca aaagggaaag gggtaccgca ccaggtccag
     5581 gcgctcggtg gtggcccctt gctgcctggc cgcctcgagg acctcatcca atagctccgc
     5641 cgtaaaccca tccgttcgtg ccgatgcgtt gacgccgagc acgcgtagac tcataaatat
     5701 cacccacgca ctaaacctca tttagcatag cacgcgcact ccaaggccgc caaggtccgg
     5761 ccacaaactc cccatcccct aggccaggac ggggtagccc ttaagctcca tcaccggccc
     5821 ctcgaggggc cacgccagca catacgtgca gcccaagggg cttttccagc ggtccaggga
     5881 aacgaagtgt agccccaccc ccacccgtgg agggcacaag cagtcaacaa gcggcaaagc
     5941 cactgcatgg gttcaatcca cacaaccggt ccgggtggcc agggtggggg acctcccatg
     6001 ctagattgaa gacatggccc tttggctggt gcgggcggga aagagtggag aaacagaggc
     6061 cttttgcctg gagagctacg aacgtctgcc tgaggagctt aaggccgaac tgccccttaa
     6121 gcgcatctgg atcctggtag aggacgaaga gaacgcatga ccgacaccca cgcccacctg
     6181 gatttcctgg aagaagccga gctggaagac gccaaagccc actttccgga actcagggcc
     6241 atcctcaccc tgggggtgga cccaacccgc tgggaaagga ccctggccct ggcccaggaa
     6301 aatgtgtacg ccgcggtggg cctccacccc acctcggccc atctgctttc ccccgaggtg
     6361 gaagaggctt taaggtatta cgcccgtcac ccccgggtgc gagccgttgg ggaaagcggc
     6421 ctggactatt actggacccc cgaaaccaag cccgcccagc tcaaggccct ggagttccaa
     6481 gcgaccctgg ccgaggagtt cgggctacct ttggtgctcc acgtgcggag taaggatggg
     6541 caagcggagg aagacctggc cgcctggctc ctcgcccacc gaccccaaag ggtggtcctc
     6601 catgcctttg gcgggcaccc ggccctcgag gcagcgggcc tcgaggtggg agcctacttc
     6661 agcttggcag gccccctcac ctacaagaaa aaccaggccc tccgggaagc ggcccaaagg
     6721 cttcccctag accggctcct ggtggaaacc gacaccccct tcctgccccc agagccccac
     6781 cggggaaagc gcaaccttcc ccactacgtg cgccacaccc tgaataggct tgcggaggtg
     6841 cggggaatga ccttggagga aatggaatcc atcaccgacc agaacgcgga aacctgcttc
     6901 cgctggacat agcccacccc ctctgtttgc aagcttcctg acccccatgg gtcataatga
     6961 aaggcggtat gagaaagctc tttttacttc tcttcctcct cctaaccgcc ttggccgccc
     7021 ccaagttggt ggtggagccg gacgatgggg tcaagccgct actggacctc atcgcctcgg
     7081 cccgggagga gatcctggtg aagatgtacc tctggacccc aagccgcctg gacgtggtgg
     7141 acgccttggg ggaggctgtg gcccgaggcg tgaaggtaaa ggtccttttg gagcgggagc
     7201 cctccggggg acgggtggac ctcacggtgt ttcaggccct gaaggaacgg ggcgtggacg
     7261 tcaagctcac cacccccttc cgcttcgtct tcgtccacga gaaaagcctg gtggtggacc
     7321 ggaagctggc ctgggtgggc accatgaacc tcacgggaag ctcctttacc gccaaccggg
     7381 agtacgccct catcctggac gatcccaggc aggtggcgga ggtggtgaag gtctttgaag
     7441 cggactggga ggggaaaagg ctggacctat cccaggccct tctcgtctgg gccccaagcc
     7501 gcatcctggg cggggtcaag gagggcaacg cccgggaaac cctcctcgcc ctgatccgtg
     7561 gggccaagag ggaggttttc ctggagcacc aggccatggc cgaccccgag gtggtggccg
     7621 ccctccagga agccttggcc agagggatcc gggtccgcct ggtgggaagc ccgcaggagc
     7681 ccggggacac ctacttcctg gcaggagcgg aggagctaag gcgggccggg gcggatctcc
     7741 gcttcctacc cgatccctac gtgcacgcca aagccctggt ggtggacggg gaggtggccc
     7801 tggtgggaag cctgaacctg agcgccaact ccataaacgc caaccgggag cttgccgtgc
     7861 gcttcacccg caaggaggcc cccgaggcct tcgccaggct cctttccgtg atggaaaggg
     7921 acttccaggc agggcttacc gaaaacacct ttgccctgcc ccccctggaa gggatcatcc
     7981 cttggcagga agcccccagg tactttggcc gcatcgccac cgtggaaggc ctcatccagc
     8041 aggtggagga ccggggcacc gtggccttcc tccggtttgg ccccggggaa agcgacctga
     8101 ggctggtggt cttccccaga aactacggcc tcttccaaca gcccttcccg caaagctatc
     8161 tgggtcagaa ggtaagggcc aaaggacgca tcgtcctcta cgccgggtat tacgaaatca
     8221 tactggagga tccctcggcc ctcgaggtgc tggatggaag cccttaaggc cctaggctac
     8281 gagataagcc ccatagaagg gggcttttac ggggagaagc gccggggggg cgtggtctac
     8341 caggtcttct actcggagga aggggacctt cgcctaaggc gcctccgctt cttaaaggaa
     8401 gaggccaggc ccttaagcct ggccggggtg gaaggggagt gggcggcccg gtaccagctc
     8461 gaggagaact tcttcgccgt ggtgccccaa gaggaccttc cctccttggt cctggccttt
     8521 gaacgccttg acctcggggc agaaaccccc taaactcaag ggcaatatgc gcccgtcttg
     8581 tcttaatgac gcctagacgg ggggcataac cgcctggccc ccccggtccc ctatggccgg
     8641 gggggccaaa gcttaaagga ggagagatgc gggttctggt acgggacttg aagaagcatg
     8701 tgggcgaaga ggtggagctt ttgggctttc tccactggcg gcgggacctg ggccggatcc
     8761 agttccttct ccttcgggac cgaagcggca tcgtgcaggt ggtgaccggt gggcagaaac
     8821 tccccttgcc ggaaagcagc ctgcgggtaa ggggccaggt ggtggagaat cccaaggctc
     8881 cggggggcct cgaggtgcag gcaaaggaaa tagagatcct ctcccctgcc ctggagccca
     8941 ccccggtgga gatccccaag gaggaatggc gggcaagccc cgacaccctt ctggaatacc
     9001 gctacgtcac cctaaggggg gagaaggccc gcgcccccct cagggtgcag gccgccttgg
     9061 tgcggggttt taggcgctat ctagaccggc aggatttcac ggagatcttc acccccaagg
     9121 tggtgcgggc cggggccgag ggaggctcgg ggcttttcgg ggtggactac tttgagtacc
     9181 gggcctacct ggcccagtcc ccccagcttt acaagcagat catggtgggg gtgtttgagc
     9241 gcgtctacga ggtggccccg gtctggcgca tggaggagca caataccagc cgccacctga
     9301 acgagtacct gtccctggac gtggaaatgg ggttcatcga gggggaggag gacctcatgc
     9361 ggcttgagga aaacctcctt caggagatgc tggaggaagc cctttccagc gccggaaacg
     9421 agatccggct tttggaagcc gagtggccct ccttccccaa ggaaatcccc cgcctgaccc
     9481 atgccgaggc caggagaatc ctgaaggaag aactgggcta ccccgtgggc caggaccttt
     9541 ccgaggaagc ggagcgcctc ctcggccagt acgccaagga gcgctggggt tcggactggc
     9601 ttttcatcac ccattacccc cgaagcctta ggcccttcta tacctacccc gaggaaaacg
     9661 gcaccaccag gagttttgac ctcctcttcc ggggcctgga gatcacctcc gggggccaga
     9721 ggatccaccg ctacccggac ctggtggaaa gcctaaaggc caagggcatg gaccccgagg
     9781 ccttccaggg gtacttggag gtcttcaagt acggcatgcc cccccacggg ggcttcgcca
     9841 tcggggccga gcgcctcacc cagaagcttc tgggcctccc caacgtccgc tacgcccggg
     9901 ccttcccccg ggaccggcac cggctcaccc cttagtacca ccccggcgag ccaccccact
     9961 ttgcctagca gcaggatggg gaccccggta taaaggccct ctagaagcgg tcaaagagga
    10021 tggcccgctt gacctcctct atgagctggg ttacggggat atcccggggg caggcctcgg
    10081 tgcagttata ggcggtgcgg cagcgccaaa ccccgcttcc cgagcccagg gccttgaacc
    10141 gctccctttt tccccggtcg cgggagtcaa agaggaagcg gtgggcctgc acgatggccg
    10201 ccgggccgat gtagtgcccg ttcacccagt agacggggca gctggaggtg caggcggcgc
    10261 agagaatgca ccgggtagcc tcctcgtaac gcgcccgctc ctcagggctt tgcaggcgct
    10321 cccgggccgg gggaggctcg tcgttgatga ggtagggctt caccgcccgg taggcggcga
    10381 agaagggctc catgtccacg atgaggtcct tctccaccgg caaaccccgt atgggctcca
    10441 cggtgatcac gcttcccagg tccttcacca gggtcttgca ggccaggcgg tttctgccgt
    10501 tgatgagcat ggcgtcggag ccgcagatgc cgtgcccaca gctccggcgg aaggccaggg
    10561 tgccgtcctg gtcccacttc accttgtgga ggaggtccaa aacccggtcc cacggttcgg
    10621 cctccacctg gtaggtgtgc caggtgggct tctggtcctt ggcggggtca aagcgaagga
    10681 tcttcagggt tacctgcatg gcacctccta gtaggtgcgg gccttgggct caaagcggcc
    10741 caggaccacg ggcttgtagc ggaaggtcac cttgccgtcg gccaccttgt aggccagggt
    10801 gtgcttgagc cagttctggt cgtcccgctc agggtagtct tcccgggcat gggccccgcg
    10861 ggactcggtg cggtttaggg cggagtgcac cagggcctcg gagacctcga ggagataccc
    10921 aagctccagg gcctccacca gctcggtgtt gtaggcatcc cccttgtcgt caatggagat
    10981 gtttcggtag cggtccatga gctccttcag gatctccacc tgcttggcca agagctcccc
    11041 ggtgcggaag acggaggcgt tgtccatcat ggtttgctgg agctcggccc ggagcgccgc
    11101 caccttctcc ttgcccgtgg agttcttgat gcgctcaatg cgctcgcggc tttcgcgcag
    11161 gtgctcctcg gtgagctcgt ggtagtcggc atccttggcg aagcgggctg catggatccc
    11221 ggcgcgccgg ccaaagacca ccaggtcccc caaggagttg gtccccaggc ggttggcccc
    11281 gtgcaggctc acgcaagccg cttccccagc agcgtaaagc ccgggcacca cggtgttgtt
    11341 ctcgtcccgg atgacctggc cccagagggt ggtgggaatc ccccccatgg cgtagtgggc
    11401 ggtgggcatc accgggaccg gctccttcaa ggggtccacc cccaggtaga tgcggctgaa
    11461 ctcggtgatg tcgggaagct tcttctcgat gacctcaggg ggcaggtggg tgaggtccag
    11521 gagcacgtgg tccttcttgg ggcccacccc ccggccctcc cgcacctcca ggtacatggc
    11581 ccgggaaacc atgtccctgg gggccaggtc cttgatggtg ggggcatagc gctccatgaa
    11641 gcgctccccc agggcgttcc tcaggatgcc cccctccccc ctggcccctt ccgtgaggag
    11701 gatgcccagg gggtaaagcc cagtggggtg gaactggtag aactccatgt cctcgagagg
    11761 aagccccttg cggtagagga tggcctgcag gtccccggtg agggtgtagg cgttggaggt
    11821 caccttgtag atgcggccaa agccccccga ggcgatgacg atggccttgg cctggaagag
    11881 gtgcagttct cccgtggcca gctcgtaggc caccagaccc ttggccaccc cgtcctcaac
    11941 gatgacatcg gtgacgtgga actcgttgta gaaggtgatg ttgtgcttca cgcactgctg
    12001 gtaaagggtc tggaggatca tgtgcccggt gcggtcggcg gcgtgggccg cccggtgcac
    12061 cggggccttg ccccagtcct tggtgtggcc gccaaagcgg cgctgggcga tcttgccgtt
    12121 ggggagccgg tcaaagggaa ggcccatgtg ctccagctca atcaccgcct caatgacctc
    12181 cttggcgaag acctcggcgg catcctggtc ggtgaggtaa tcccccccct tcaccgtgtc
    12241 gaacatgtgc cactcccagt ggtcctcctc cacgttgccc agggccgccc ctatcccccc
    12301 ttgggccgcg cccgtgtggc tcctggtggg gtaaagcttg ctgaccaccg ccacatccgc
    12361 accttccctg gccgcataaa gggcggtggc aaggcccgcc ccgcctgcac ccaccacgat
    12421 gacctcgtgc ctgtgcgcca tactacttca ccccgaaatc gaaattgaaa agcgaaagac
    12481 tccccaggaa gaaaaggaag gcgatgaggc tgtagaccac caccttggtc caaaaacgcc
    12541 tcaccgggtg ccgcacccag tcgtccagga cataacggag cccgttcccc ccatggagga
    12601 gggccaaggc caggatcagc cagtcataaa ccttccaggt ggtctgggaa agtctcttag
    12661 ccacatagtt gtagtcaatc tggttcaggt ctattaggat ggcgttcatc cacatgtggc
    12721 cgatgaggag gaagaccaac accaccccgg agatgcgcat gaaaacccac cagtagagct
    12781 ccaggttggt gctggcctcc agcttggcct cctcgtagcg cctggactta atcgccatga
    12841 ccacccccca ggatcccccc tccgatcttc aaaaggaagg gaaggtagaa gatcacgaaa
    12901 agaacccaga ccccgtacca aagctgccgc tggtagcgca ccccccaggc ggtgaagtcc
    12961 atgaggatga tcctgagccc gttgaacccg tggtaaagca ccccggcgat gagaagaagg
    13021 agccctatct ggaaaaccgg ctggtggtag aacttcatga gggcgttgga cacctccggg
    13081 ccccacatgg cgcttgcgat gttggccacg tggagcatga ggaagaccag aatgcccagg
    13141 cccgagatcc ggtgcaggta aaacgcccac tgcccttctc ttcccctgta catggcacct
    13201 ccttgccggg gacatcatac cacctttctt aaggaaacca ccgtctgggg cttatttcct
    13261 ccccatccat accccatccc cgtataagag gcgcatggaa gggagcttcc ctccacc
//
