LOCUS       NC_020291.1            22096 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_020291.1 Clostridium saccharoperbutylacetonicum N1-4(HMT),
            complete sequence.
ACCESSION   NC_020291
VERSION     NC_020291.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:47:19
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2349341
            Orig. end    :: 2371437
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22096
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2359341:2361437]"
                     /cutoff="10000"
                     /detection_rule="(Flavoprotein and Phea_decarb and not
                     ubi_syn)"
                     /neighbourhood="10000"
                     /product="hydroxybenzoate2phenol"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12096
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Flavoprotein and Phea_decarb and not
                     ubi_syn)"
                     /neighbourhood="10000"
                     /product="hydroxybenzoate2phenol"
                     /protocluster_number="1"
     cand_cluster    1..22096
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Flavoprotein and Phea_decarb and not
                     ubi_syn)"
                     /kind="single"
                     /product="hydroxybenzoate2phenol"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22096
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydroxybenzoate2phenol"
                     /region_number="7"
                     /rules="(Flavoprotein and Phea_decarb and not ubi_syn)"
                     /tool="gutsmash"
     CDS             1011..1808
                     /gene_functions="resistance (resist) BCII (Score: 312.8;
                     E-value: 1.1e-95)"
                     /gene_kind="resistance"
                     /locus_tag="ctg1_2066"
                     /transl_table=11
                     /translation="MKKYKHVFTKFLSVLLSIFILSLIACSNNVKENSKAKESVLEIGS
                     DDSNFVQLTKINDNVWVHTTYYSYNGSRTLSNGLLILTSKGLVLIDTPWTDEQTKELIK
                     LTKEKFKQDIIAAVITHAHIDRIGGIKTLLDKKIDVKSTTLTAQLAEKYGFDKPNSLIN
                     NDDEVLEFGKTKLEVYFPGKGHTIDNIVVWLPEDKILFGGCIVKPVESNSIGNTADADI
                     KEWPNSIKNLMNKFSDSEIVITSHGSWGNKQILTHTLDLLKKA"
     CDS             2079..3248
                     /locus_tag="ctg1_2067"
                     /transl_table=11
                     /translation="MKNNVDFNSGEYQLHSNPNFNYQLNRTYNVSNGNLDEILELAKKI
                     TDIKVWEKEMMVLAKKALKEERIKDAIAYFRMTEFFMYDGNPDKIKTYDKAIELFYKYH
                     EELFQSGILKFDRVPYDQGYLPVIHAVPEGECIDTILIHGGFDSYMEEFLPSLLYLREN
                     GFDVYLFEGPGQGNVLRKQGITFSIKWERPVKALLDYYNLNDVTIIGISMGAILAPRAA
                     AFENRIKRVVAWSVCVNMFELLLDAIPTAEQEVLKELLGQNDKDTINNIMYNQMEKEPL
                     IDWAMHHGFYNMGVNNPYDYMLAANKYEYRDVADRITQDFMLLGAEKDHLIRIEKYKDA
                     IDSLKNVKSLTYRMFTEKENAASHCNTGNPKLVLDTIISWIKIIKNREK"
     CDS             3263..3508
                     /locus_tag="ctg1_2068"
                     /transl_table=11
                     /translation="MESILRAVKLIKDIVKNKIQREKLCRLNSKVKQMRTYKKSAKHNT
                     ELNIKNLRIHSHLRFFYRTAADKKLRKNTLNIKTTL"
     CDS             3818..4327
                     /locus_tag="ctg1_2069"
                     /transl_table=11
                     /translation="MLEYIILGFLMSGEMSGYDLKQKMIESTSNFFDAGYGSIYPALKR
                     MEAKCVISLREIIEGGKYKKLYAITELGKSEFLNWLELPVEFSRTKPDHLIKIFFFKFL
                     PKEKAITHLKFFIKEVESFISIFGKYENQVKEQFDVYQFSTFLFGLGYYEYIVKYCNDL
                     LNKLND"
     CDS             4340..5095
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2070"
                     /sec_met_domain="Fer4 (E-value: 8.9e-06, bitscore: 23.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0013, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRRQNVRNAFLIISFLLFPITQFYFSPFLIIWGASKGLITASAV
                     IFSMFFLFSLLFGRVFCGWLCPCGAMQEILFKVNNKNPKTGKLDYIKFFIWVPWMITIV
                     TVALLAGGFKRADYFFVMDHGISVSNIYMYIPYYIVILLFFLNSIIFGKRANCHYLCWM
                     SPFMIIGRKISNFFNIPSLRIKSEKDKCINCKKCNSECPMSLDVNNMVKCDKLENHECI
                     LCGKCADICPKNVIKFNFGRIQFAKKNRI"
     CDS             5117..5686
                     /locus_tag="ctg1_2071"
                     /transl_table=11
                     /translation="MKVITILGSPKRHGKTAKALDMFEENLISQGHEVERVQLSEHIIK
                     GCVGCYACMANNDGPGCILKDDAVLIFKRMISADAVVYASPIYCYDFTSQLKTFIDRHY
                     CLTINFGSPNHTSSIEGKKVALLITCMGREEGNADLAEEIFDRSMRNVLKCNLVGKYTV
                     PLSEAPDFNDRAKKVVDKLAKDIIQK"
     CDS             5827..6252
                     /locus_tag="ctg1_2072"
                     /transl_table=11
                     /translation="MMDKNIKSKTVSKRIMQLIFVIIGILAIYTAYLGFAYGAVNWYYG
                     FPVGQEYSKGFLMLDSNLRFYSGLWLGVGIIMLWMIPRIDKDKDMLRVIAILFFFGGIG
                     RLISILTCGLPSYMYMVFVLLELSFPLLTLWQKRILK"
     CDS             6668..8851
                     /locus_tag="ctg1_2073"
                     /transl_table=11
                     /translation="MKSKKIITVIISAALCLGMLVGNNNFQTIAKAAEVNVNLIKNGNF
                     DKNLDGWGSYTAYGGDGRISLKDGAINIQVDNCGTVSYGVQVYNDGFKMYKNGKYHLEF
                     DVSSTTDRKIDYRIQRNGGDYRSYFGETIDISKDVKKVSQDFVMNDENDMSPRFAFNLG
                     NVTGKNINPHSIKIDNVKLVLIDDTGVQYDEEKPEQKIVLNQVGYKPGDKKKVVFRAQS
                     EDSKFRVVSAETKKVVYEGNINGNSYNEAAGETDRFGDFSSVTVPGKYTIETDGLGSSY
                     EFTIGQDVYKNVFKDLVRFFYMQRCGQEIPKEFGGTWSHPACHTDLAKIYGSDKKIDVS
                     GGWHDAGDYGRYVVATSKAVADLLSAYEDNKGAFGDDFNIPESGNGIPDVLDEVKYQLE
                     WMLKMQEPLSGGVYHKVTCANFPGTVMPQEEKEELIVCPISTTATGDFAAVMAMGYQNF
                     KDVDPSLAQKCLVAAEKAWAYLEKTPNAVVKNPDGIVTGEYGDSDDTDERYWAAAQLFK
                     ATGESKYDNAFTEMAKAKIQNGYDWALVGDYGNMAYLSAKDANQNVANNIRNNILNEAQ
                     KIVALDRNDGYNVPNGKDYSWGSNMGMNNNAVLLAQAYKLSPNPEYLEYAKEHINYCFG
                     KNSLSKCFVSGYGSDSLKNPHHRPSIVQGKAIPGMIAGGPNKNLEDPIAKNLLEGKAPA
                     KCYLDNSESYSTNEVDIYWNSPIVHAMAELNMD"
     CDS             complement(8989..9879)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     78.5; E-value: 9.2e-25)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2074"
                     /sec_met_domain="LysR_substrate (E-value: 1.8e-27,
                     bitscore: 94.4, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 8.5e-23, bitscore: 78.5,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIRQLKYFVVIAEEGSITKAAERLFMAQPPLSRQLQTIEDKLGV
                     TLFNRTNKKSMSLTPQGRIFLKNARRILYTMDEAITEVQEYNLQMSKKLSIGTTIYCSE
                     IMLPVLKNFRKKYPFTIPEIHEGNISHLMDLLKNHTIDLVVSARPFNTKGYITKELELD
                     KCVFVASKDFEWKKEHISLEEISTVPLLLLNAPDSTSLYKKIISEFEKKELKLNVSCLC
                     HDSGLLLKMILSNFGATILPNSMVDNMLGEFMHVIPIKNNPWTTTPNLIWRSEGYISST
                     LGEFIKTFESQFKVN"
     CDS             10001..10570
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydroxybenzoate2phenol: Flavoprotein"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2075"
                     /sec_met_domain="Flavoprotein (E-value: 4.4e-27, bitscore:
                     93.2, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNVIVSITGATGSIFGIRILEILKDIKEVKTHLILSSWGKKTLEA
                     ETNYTMEEVEQLADFIYETADLGARISSGSFQVDAMIIAPCSMKTLASIRIGLADNLVS
                     RAADVILKERRKLILLTRETPLNTIHLENMLALSKMGTIILPPMPAFYNNPQTINDIVN
                     HIAYRTVDQLGIILPNLKRWDGLREK"
     CDS             10669..12096
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydroxybenzoate2phenol: Phea_decarb"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2076"
                     /sec_met_domain="Phea_decarb (E-value: 1.7e-184, bitscore:
                     611.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAYRDLREFLELLEKEKQLVRIKDEVMPEPDLSAIGRCAPDMESA
                     PAIFVENIKGYKSPVVLNVHGSWQNHALMLNMPKDTPVKDQFFRLKELWGKYPVKPVWV
                     DKKNAPVKEVVIEEDINLFDVLPLFRINEFDAGFYLSKALIVTRDPNKPENYDEQNCGI
                     YRIQVKGKDKVAIQPMPFHDIAVHLRNAEEKNERLPIAICLGNDPVLSFMASTPIAYVQ
                     SEYDFAGALKGEPIELTKTENSNLDIPARSEVILEGYIEPRVREIEGPFGEFPGSYSGA
                     RLQPIVKITKITHRKNPIFENLYLGMPWTEVDYLIALNTSIPLYDQLKRDFPEVQAVNA
                     MYTHGIGAIVSTKSRFGGYGKAVAMRLLSTPHGMSYTKIVIVVDEFVDPFNLEQVMWAL
                     TTRVRPDKDVFKVPYAPGMLLDPSSEPAGMHTKLVIDATTPVAPDFGRDTELLGSPIGV
                     EKWTKILRDLVKEGGNK"
     CDS             12096..12326
                     /locus_tag="ctg1_2077"
                     /transl_table=11
                     /translation="MKCPRCDSELVSVMVKSPVGNAWEVYLCDTCKFSWRSTEGENITD
                     PEQYDKRFKLNSEEFNKLDQIPPVPPLLKKK"
     CDS             13239..14570
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2078"
                     /sec_met_domain="Aldedh (E-value: 2.1e-30, bitscore: 104.0,
                     seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQLGVFETATEACVAATVAQKELVLKYTLEDRDRFIGNIRKNII
                     GNMEMLAEMEFDETGYGRLEDKLAKNTGAVMLSQGTEAIPQNMYASDKGLTVEYYAPFG
                     VVGAVTPVTNPVATVVGNGIANVAAGNAIVFNAHPSAKKTSARAVHLINKAVIEVGGPG
                     NLFTMPAEPTLDSLNEIMAYPSVKLLIGTGGPGMVKTLMCSGKKVIAAGAGNPPSIIDE
                     TVDLAKAAAGIYESASFDNNLLCIAEKELFVVDTIFDEFMKRLESVGAYRVNTEEGKRL
                     TDICVVKASGGSYAANKKYVGKCANIILKAAGIKINNDPRMVIFEAQNDDKLVHTEQMM
                     PIIPVVRCKNFEEAVERAVAAEHDCKHSASIWSNDINRVTAFGKVINTTIFVQNGGTMA
                     AFGIGGTGTNAPTIATPTGEGVTGPQSFVRRRRFCMAGGGNYLL"
     CDS             14634..15545
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2079"
                     /sec_met_domain="PTA_PTB (E-value: 5.6e-44, bitscore:
                     149.1, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIESFQDLVKNAQSIEKKSRIAVVAAHDKHTLQSIVKAKKDNLI
                     IPILIGNEMVIVKMLIELGEDSREYKIVHARNIDECLVIAVEMIHKHIADLLMKGKLET
                     STMMKVILKKENDLKKDRTMSVVGFFETEKYHKLLSVSDVAVNIYPDVERKKDILLNAV
                     KILNLMGVENPKVALLTATENINPKMPETEHANDLKQMNKNGEIQGCIVEGPISFDLAT
                     SREATRIKGYESQVAGDADLLLMPDLVSANVLGKCLTGFAGAQTAGLLVGAKVPIILTS
                     RSAEASDKYYSIALAAYVAQNY"
     CDS             15570..16673
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Butyrate_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2080"
                     /sec_met_domain="Butyrate_kinase (E-value: 1.5e-112,
                     bitscore: 374.3, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKTYVILAVNTGSTSTKIAVFENEKEVFNKNISHDIDKLKEFKQI
                     QDQLGYRKEIVEQELKAHRISIKNIEIFVGRGGGLVPIKGGTYLVNSKLIEHASKGMSG
                     QHPAQLASQICNIFVKKYGGRAYVVNPPDVDEFEEIARITGLYGVYRESKVHALNQKEV
                     ALRYCNTNNKKYENSKLIVCHIGGGISVTAHNNGRMVDSNDIINGDGPMTPTRAGALPI
                     TKVVRMCYSGRFTEKELYNKLTKESGLIDHLGTSDIRKIEKRIMLGDRYAKLVYNAMIY
                     QIGKSVGAAACVLKGKVDAIILTGGIANSDYLVSKLDEYISWISKIKVIPGEFEMEALA
                     AGALRVVRGEEEAILYTGHPIWSGVTA"
     CDS             17575..18987
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2081"
                     /sec_met_domain="PTS_EIIC (E-value: 2.3e-18, bitscore:
                     64.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METNKSSLKGNVQRLGSFLSGMVLPNIGAFIAWGLITALFIPTGW
                     MPNEYLGKLVGPMITFLLPLLIGFTGGKMVYGHRGGVVGAIATAGVIIGASIPMFLGAM
                     IMGPVGGYVIKKFDKLIEDKVPTGFEMLVNNFSAGIIGGIVAILAYTCIEPVVSTFSNT
                     LGSLATIVTNLGLLPLIDIFIEPAKILFLNNAINHGILTPLGVQQAADAGKSIFFLLEA
                     NPGPGLGILLAYSLYGKGNAKQSAPGAIIIHFLGGIHEIYFPYILMKPILILAAIAGGI
                     SADLVFVLTHAGLRAASSPGSIFAILAMTASDSYVGVIGGVAVGAIVSFLVGSLILKAS
                     KDNAEEENFDDAQAKIKDMKAESKGAKVEEAKVSLSKTDVKMIVFACDAGMGSSAMGES
                     ILKKALKDAGITGIDVKHSSVDSIPQEANVIFTQENLIERARSSANNAASIITIKNFLD
                     RSKYDEFINTLK"
     CDS             19360..20130
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     244.5; E-value: 5.1e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2082"
                     /sec_met_domain="Fe-ADH (E-value: 4.7e-73, bitscore: 244.5,
                     seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LIIKDEKSGVKYPLADYELTPDMAIVDVELMINMPKNLTAASGID
                     ALIHAIEAYVSVLASEYTNGLALEAIRLIFKYLPQAYEEGTTNVKAREKMAHASTIAGM
                     AFANAFLGVCHSMAHKLGAEHHIPHGVANALLINEVIRFNAVDNPLKQTAYPQYKYPNV
                     KTRYARIADYLNLGGKTEDEKLELLIKAIDELKEKLDLPKNIKEAGVTEKKFYRTLDEM
                     SEQAFDDQCTGANPRYPLIKEIKQMFINAYDAAE"
ORIGIN
        1 ctgtttgcct ctttaccact gcctaatgta gaagatagta tagaagaaat tcgatatgca
       61 aaggaaattt tgcaggttga tggttttgct ttacctacta acacgcaagg agtttatcta
      121 ggaaaccctt gcttaaatcc tatatttgaa gagttaaaca ggcacaaagc cgtggttgtt
      181 cttcatccca ataagccaag cagtgttcct gaaaatgttg tggaagggtt acccattcct
      241 atgatggaat ttttctttga tacaactcgt actgtaatta atctgatatt aaaagggaca
      301 ttaaagaaat ttcctgatat taaattcatc attccccatg cgggtgcttt tctgccaata
      361 cttgctgata ggattgcttc tgcaattcaa atggcaccgg actcatttgg tgagaatata
      421 aaaggagaag cagataggat agatatctat gatgctttaa aaaatttata ttatgatgta
      481 gctggagttt gtctacctag acaattagcg gctcttttac agattgttaa tgttgatcat
      541 ttattatatg gaagtgatta tccttatacc ccgaaatttg gatgtattat actagctgat
      601 gctttagata aaaccaattt gcttaataat gaacagcgtc atgctgtcta ccatgataat
      661 gcattaaaat tattttcaca tttaaaagat gagtaaaatt tattaagaga aaaattaaaa
      721 gttatcaata aataatacag ttaatttatt gataacttta atgttaatga ttatgacact
      781 acttattttg ggagtacaga atattttaga catgcaggcc gctcaacaat accttatatt
      841 cttcgcttga aaatggagta tttataaaaa tagacagtga ttgctgaaat cctgttgtta
      901 taagaatatt atctgatgtg ttaaaatata gattaattat tggaattcat aagataaact
      961 tacagcaata ggaaattata atatgatatt agaaggaaag gattttattt atgaaaaaat
     1021 ataaacatgt atttactaaa ttcttaagtg ttttactaag tatattcatt ttatctctaa
     1081 tcgcttgctc taataatgtc aaagaaaata gtaaagcaaa agagtctgta ttggaaatcg
     1141 gatctgatga ttctaatttt gttcaattaa ctaaaattaa tgataatgtc tgggtacata
     1201 caacatacta tagctataat ggaagtagaa ctttatcaaa tggtttgtta attttaacat
     1261 ctaaaggatt agtactaata gatactcctt ggactgatga gcaaacaaaa gaattaatta
     1321 aattaacaaa ggaaaaattc aagcaggata ttattgccgc agtaataaca catgctcata
     1381 tagatagaat tggtgggatt aaaacattat tagataagaa aatagatgta aaatctacca
     1441 cattaacagc acagctagct gaaaaatatg gttttgataa acctaattcg ttaattaata
     1501 atgacgatga agtgttagag ttcggaaaaa ccaagctaga ggtatatttt cctggtaaag
     1561 gtcatactat tgataatatt gttgtttggt taccagaaga caagatttta tttgggggat
     1621 gtattgtaaa gccagtggaa tctaattcaa ttggaaatac tgcagatgct gatataaaag
     1681 aatggcctaa ttctattaaa aatttgatga ataagttttc tgattctgag atagtcataa
     1741 catcacatgg aagttggggg aataaacaga tattaacaca tactcttgac ttattaaaaa
     1801 aagcataaag atatatggta ataatctcat ttaagtttaa ctaaatatca aataatgata
     1861 ttcacctcta taagtagttc gtttgcaact actataattg gcatagaaaa tatacaagca
     1921 ttgctatcta tgccaattta acttgatata tgagatatat ttttaaggga aagttattat
     1981 tatctgttca aacattttta aaacaattat atatactaaa gttcatatag aagtatattt
     2041 atgatacttt gagtatagtg agaggaatgg tagttaatat gaaaaataat gttgatttca
     2101 attcaggcga atatcaatta cactctaatc ctaattttaa ttatcaatta aaccgcacct
     2161 ataatgtaag taatgggaac cttgatgaaa ttttagaact cgctaaaaaa ataactgata
     2221 ttaaagtgtg ggaaaaagaa atgatggttc ttgctaaaaa agctttaaag gaagagagaa
     2281 taaaagatgc tattgcttat ttcagaatga cagaattctt tatgtatgat ggtaatccag
     2341 ataagataaa aacatatgat aaggcaatag aattgtttta taaatatcat gaggaattgt
     2401 ttcaatctgg aatattaaag tttgaccgtg ttccatatga ccaagggtat cttccagtaa
     2461 tacatgcagt gcctgaagga gagtgtatag atacaattct aatacatggc ggatttgatt
     2521 cctatatgga agaattcctt ccttcgctgt tgtatctcag ggaaaatggc ttcgacgtat
     2581 atctatttga agggccaggt cagggaaatg tcttaaggaa acaaggaatt acattttcaa
     2641 ttaaatggga aaggcctgta aaagctttac tagattatta taatttaaac gatgtgacaa
     2701 taataggtat atccatgggg gctattctag caccaagggc agcagcgttt gaaaatcgaa
     2761 taaagagagt tgtagcatgg agtgtatgtg ttaacatgtt tgaattactt ctcgatgcta
     2821 ttcctacagc agaacaagag gttttaaaag aattgctagg acaaaatgat aaagatacta
     2881 taaataatat aatgtataac cagatggaga aagaaccttt aatagattgg gcaatgcatc
     2941 atggctttta taatatggga gtaaataacc cttacgatta tatgctggcc gcaaataaat
     3001 atgaatatag agatgttgcg gataggatta cacaggattt tatgttacta ggcgctgaaa
     3061 aagaccattt aatacgtata gaaaaatata aagatgctat tgatagtctt aaaaatgtaa
     3121 aatcattaac atacagaatg tttacagaga aagagaatgc agcaagtcat tgcaatactg
     3181 gaaatcctaa attagttctg gatactatca tttcatggat aaaaataatt aaaaatagag
     3241 agaagtagtt tttaaggcac ttatggaaag cattttaaga gctgttaaat taattaagga
     3301 tatagtaaaa aacaaaattc aaagagaaaa gctatgtcgg ctaaactcaa aagtgaagca
     3361 gatgcgcacc tataaaaaga gtgcgaagca caatacggaa cttaatatta aaaatcttcg
     3421 gatccacagt cacctgcgat ttttttatag aacggcagca gataagaaat taagaaaaaa
     3481 tactttaaac ataaaaacaa cattataaat gataatgtag tgtatttaga taatggagga
     3541 gaacgaaatc cagacagagg aggttctcct tttttgttgc gaaaaaaatg ttgatgatag
     3601 gtcttgtgaa tataacaata agtagataat taataatgca aatataaaat attcctttag
     3661 ttatatggaa tgtttattaa ggtaagcttg gtttttattg gttaatttta aattaagtgg
     3721 attaataata ttgacaatgt tattataacg agttaatatg tatctataat atatatatcg
     3781 aaatgatata tatcataaat atatatggag gtgaaaaatg ttagagtata ttattcttgg
     3841 ttttttaatg agtggtgaaa tgagtggata tgatttaaag caaaaaatga ttgaaagtac
     3901 atcaaacttt tttgatgcag gttatgggag catatatcct gctttgaaaa gaatggaagc
     3961 taagtgtgtt ataagtttaa gggaaattat cgagggcgga aaatataaaa aattatatgc
     4021 tataactgag ctgggaaaat cagagttcct gaattggctt gaactaccag tggaattttc
     4081 aaggacaaag ccagatcatc ttataaagat attcttcttc aagtttttgc cgaaggaaaa
     4141 ggccataaca catttaaaat tttttattaa agaagttgaa tcttttataa gcatttttgg
     4201 aaaatatgaa aatcaagtta aagaacaatt cgatgtttat caattttcta catttttatt
     4261 tggacttggt tactatgagt atatagtaaa atattgtaat gacttattaa ataaactaaa
     4321 tgattaggga ggatttataa tgttacgacg acaaaatgta agaaatgcct ttttaataat
     4381 atctttttta ttattcccaa tcacgcaatt ttatttttct ccttttctta ttatatgggg
     4441 tgcttcaaag gggttgatta ctgcaagtgc tgttatattc tcaatgtttt tccttttttc
     4501 attattgttt ggacgagtat tttgtggctg gttatgtccc tgtggtgcta tgcaggaaat
     4561 attatttaaa gtaaataata agaaccctaa aactggcaag cttgattata ttaaattttt
     4621 tatatgggtt ccgtggatga ttacaatagt aactgtagca ttattggcag gtggatttaa
     4681 aagagcagat tatttttttg taatggatca tggaatttca gtaagtaata tatatatgta
     4741 tattccatat tatattgtaa ttttattatt ttttcttaac tctataattt ttggtaaaag
     4801 agcaaactgc cattatttat gctggatgag tccatttatg attattggaa gaaaaattag
     4861 taactttttt aatattcctt cattaagaat taaatctgaa aaggataaat gtattaattg
     4921 taaaaaatgt aatagcgaat gtccaatgag tcttgatgtt aacaatatgg ttaagtgtga
     4981 taaattagaa aatcacgagt gcattttatg tggcaaatgc gccgatatct gcccgaagaa
     5041 tgtaattaaa tttaattttg gaagaataca atttgctaaa aaaaatagaa tataatcatt
     5101 ggaaggaagt ttttttatga aagtaataac aattttagga agtccgaaaa gacacggcaa
     5161 aacagcaaaa gctcttgaca tgtttgaaga gaatcttatt tcacaaggac acgaggtaga
     5221 aagggtgcag cttagtgagc atattattaa aggatgtgtt ggatgctatg cgtgtatggc
     5281 aaataacgat ggacccggat gtattttgaa agatgatgcg gtattgatat ttaaacgaat
     5341 gatatcagca gatgctgttg tatatgcttc tcctatttac tgttatgatt ttacctcaca
     5401 gttaaaaact tttatcgaca ggcattattg tcttacaata aattttggtt ctccaaatca
     5461 cacatcatca attgagggaa agaaggttgc tcttttaatt acatgcatgg gtagagaaga
     5521 aggaaatgca gatcttgcgg aggaaatttt cgataggtca atgagaaatg tactaaaatg
     5581 caatttagtt ggaaaataca ctgtcccgtt aagtgaggca cctgatttta atgatagagc
     5641 taagaaagtt gtcgataagt tggcaaaaga tatcatacaa aagtaactct tgtaaaaagt
     5701 attgaatcta atgcagtgaa gtttgtttat cttgaattgg taaaagaaat aaatagttgg
     5761 attataataa tttgtgtttt gtaatttata agagaggaag agtgaattaa tttgagtaaa
     5821 atagatatga tggataaaaa catcaagagt aagactgttt cgaaacgcat catgcagttg
     5881 atatttgtta taataggaat tttagctata tacacagctt atctaggatt tgcttatggt
     5941 gcggttaact ggtattatgg atttccagtt gggcaggaat attcaaaagg atttcttatg
     6001 ctagatagca acctgcgttt ttacagtgga ttatggttag gcgttggaat tataatgttg
     6061 tggatgattc cacggattga taaggataag gacatgcttc gtgttattgc aatattattt
     6121 ttttttggtg gaatagggcg cttaatatca atattaacat gtggcctgcc ttcgtatatg
     6181 tacatggttt tcgtgctact tgaattgagt tttccgcttc tcacgttgtg gcaaaagcgt
     6241 attttgaaat gatgtatacg ttaatgtacg aatagttaat ttaatatatt ataatgtttc
     6301 aacttaatat ttaaaattat gtttaagaag ccaaattttc atactgggaa tttggctttt
     6361 tatatagttt ggcatagatg attaattaat ttatagtacc aaatataata gaattttcag
     6421 gaatatcaag ccctgaaatg agatttaaag ctagctgact cagtattatt caatctttga
     6481 taactaactc atgagatgat aatctacata ataatcataa aatgtatatt tttcatcgta
     6541 aaattggaag tgatgaattt atatattttt gataagtgat tttatgcatt tcaaggaata
     6601 agaatttact tgatttttgt attatgagaa tatgtagtag taaatattag atgaggagga
     6661 atagtatatg aagtcgaaaa agataatcac agtaataata agtgcagctt tatgtctagg
     6721 tatgcttgta ggcaataaca attttcaaac aatagcaaaa gctgctgaag ttaatgttaa
     6781 tttaattaag aatggaaatt ttgataaaaa cttagacggt tgggggagtt atacagctta
     6841 tggtggagat ggcagaataa gtttaaaaga tggagcgatt aatatacaag tagataactg
     6901 tggaacagta tcatatggtg tacaagttta taatgatggt tttaaaatgt acaaaaacgg
     6961 aaaatatcat ttagaatttg atgttagttc tacaactgat agaaaaattg attatagaat
     7021 tcaacgtaat ggaggagatt atcgttctta ttttggagaa acaattgata taagtaaaga
     7081 tgtaaaaaaa gtgtcacaag attttgttat gaacgatgaa aatgatatgt caccaagatt
     7141 tgctttcaat ttaggtaatg taacaggaaa aaatattaat ccgcactcta ttaaaattga
     7201 taatgttaaa ttagttctta ttgatgatac tggagtacaa tatgatgaag aaaaaccaga
     7261 acaaaaaatt gttttaaacc aagttggtta taaaccagga gataagaaaa aggttgtatt
     7321 tagagcacaa agtgaagata gtaaatttag agttgtttca gcagaaacaa agaaagttgt
     7381 ctatgaagga aacattaacg gtaactctta caatgaagca gctggagaaa cagatagatt
     7441 tggtgatttt tcttctgtta cagtgccagg caaatatact attgaaacag atggtttagg
     7501 cagttcctat gaatttacta taggacaaga tgtctataaa aatgtattta aagatttagt
     7561 tagatttttc tatatgcaaa gatgtggaca agaaatacca aaagaatttg gtggtacatg
     7621 gtcacatcca gcttgtcaca cagaccttgc taaaatatat ggttcagata aaaaaattga
     7681 tgtatctgga ggctggcatg acgctggtga ctatggacgt tatgtggttg ctacatcaaa
     7741 agcagttgca gatcttttat ctgcttatga agataacaaa ggagcctttg gagatgattt
     7801 caacatacct gaaagtggga atggaattcc tgatgtttta gatgaagtaa aatatcagct
     7861 agagtggatg ttaaagatgc aagaaccatt aagtggtggt gtttatcata aagtaacttg
     7921 tgctaacttc ccaggaactg ttatgccaca agaggagaaa gaagaactta ttgtatgtcc
     7981 catttcaaca actgcaacag gagactttgc agcagttatg gcaatgggtt atcaaaactt
     8041 taaagatgta gatccatcac ttgctcaaaa atgtctcgta gcagcagaaa aggcttgggc
     8101 ataccttgaa aagacaccaa atgctgtggt taagaatcca gatggtattg taactggaga
     8161 atatggtgac tctgatgata cagatgaaag atattgggca gctgcacaac ttttcaaggc
     8221 cactggtgag agtaaatatg ataatgcctt taccgaaatg gccaaggcaa aaattcagaa
     8281 tgggtatgat tgggctcttg taggcgacta tggtaatatg gcttaccttt cagcaaagga
     8341 tgccaatcaa aatgttgcta ataatattag aaataacatt ttaaatgaag ctcaaaaaat
     8401 tgtagctttg gatagaaatg atggttataa tgttcccaat ggaaaagatt attcttgggg
     8461 tagtaatatg ggcatgaata ataatgctgt acttcttgcg caggcatata aactttcacc
     8521 taatccagag tacttggaat atgcgaaaga acatattaat tattgctttg gtaaaaattc
     8581 attaagcaag tgctttgttt caggttatgg ttccgattca ttaaaaaatc cacatcatag
     8641 accatctata gtacaaggta aagcaatacc aggtatgatt gcaggtggcc caaataagaa
     8701 tctagaggat ccaattgcaa aaaacctgtt agaaggtaaa gctcctgcta aatgttattt
     8761 agacaattca gaaagttatt caactaatga agtagatatt tactggaatt caccaattgt
     8821 gcatgcaatg gctgaattaa atatggatta gaataattga aatgaataga gtaaatgaag
     8881 gtagattaga tagaaatatt taatctgcct tcatctttca ataagggatt gaaagatttg
     8941 aaaattttgt tattaaggac aggtcaacat taataaataa taatagttct aatttacttt
     9001 aaattgagat tcaaaagttt taataaattc tcctaatgtt gaggaaatat atccttcgct
     9061 tctccaaatt aaatttggag ttgtagtcca aggattattt ttaattggaa tgacatgcat
     9121 aaattcgcct aacatattat caaccattga attcggcaaa attgttgcac caaaattact
     9181 taaaatcatt tttaaaagta aaccagagtc atggcataga catgaaacat ttaactttag
     9241 ttcttttttc tcgaattcac ttatgatttt cttatataag ctggttgaat ctggtgcatt
     9301 aagaagaaga agtggaacgg tggaaatttc ttcaagagaa atatgttctt ttttccattc
     9361 gaaatcttta gaagcaacaa agacacactt atctagttcc agctccttgg ttatgtaacc
     9421 ttttgtatta aaaggtcgtg ctgaaacaac taggtcaatt gtatgatttt ttaataaatc
     9481 cattagatga gatatattcc cctcatgaat ttcaggaata gtgaagggat attttttacg
     9541 gaaatttttt aaaacaggaa gcataatttc tgaacaataa atagtggtac caattgatag
     9601 cttttttgac atttgcagat tatattcttg tacttccgta atagcttcat ccattgtgta
     9661 aagtattctt ctagcatttt ttaaaaaaat tctgccttgt ggagtaagtg acatactttt
     9721 tttgtttgta cgattaaaaa gagtgactcc aagtttgtct tctattgttt gtagctgtct
     9781 agataagggt ggctgagcca taaataagcg ttctgctgct tttgtaatac taccttcttc
     9841 tgcaattaca acaaaatatt ttaactgacg aatatccatg atatagttaa ctcctttctg
     9901 ttatacctta aaggtattaa aacatacatt attgatattt tcaatgtatg ttttctaagc
     9961 ttataataat aatgcagaaa caagaaaaag aggtgataca ttgaatgtta tagtatcaat
    10021 tactggagca acaggatcaa tttttggaat acgtattcta gaaatattaa aggatattaa
    10081 agaagtaaaa actcatctta tattatcaag ctggggaaaa aagactttgg aagcagaaac
    10141 aaactataca atggaagaag tggaacagct tgctgatttt atatatgaaa cagcagacct
    10201 tggagcaaga atctcaagtg gatcatttca ggtagatgct atgattattg caccatgcag
    10261 catgaaaaca cttgcatcca ttcgcattgg gcttgcagat aatcttgtat cacgtgccgc
    10321 agatgttatt ttaaaggaaa gaagaaaatt aattctctta acaagagaaa cacctctgaa
    10381 tacaattcat ttagaaaata tgcttgcatt atctaagatg ggaacaatta tattgccacc
    10441 aatgccagca ttctataata atcctcaaac aataaatgac atagtaaatc acattgcata
    10501 tagaacagtg gatcaacttg gaatcattct tcctaattta aaacgttggg atggattaag
    10561 agaaaaatag gtttaaatat actgggagat ataacaagaa atgaaacagg tatatttctg
    10621 ttttaaataa ataccatata attctatgat aaatcaggag gttaaaaaat ggcttacaga
    10681 gacttaagag aatttttaga actattagaa aaagaaaagc aattagttag aataaaggat
    10741 gaggttatgc ctgaaccaga ccttagtgca atcgggcgat gtgccccaga tatggaaagt
    10801 gcacctgcaa tttttgtaga aaatattaaa ggatacaaaa gtcctgttgt gcttaatgtc
    10861 cacggatcat ggcaaaacca tgcactaatg ttgaacatgc ctaaggatac tccagtcaaa
    10921 gatcaatttt ttaggctaaa agaactttgg ggtaagtatc ctgtgaaacc ggtctgggtt
    10981 gataaaaaaa atgctccagt aaaggaagtt gtaatagaag aggatataaa tcttttcgat
    11041 gtacttccgt tatttagaat taatgaattt gatgctggat tttatctttc aaaagcactt
    11101 atagttacta gagatcctaa taaacctgaa aattatgatg agcaaaattg cggaatatat
    11161 cgtattcaag taaaaggaaa ggataaagtt gcaattcagc cgatgccatt ccacgatatc
    11221 gcagttcact taagaaatgc tgaagaaaag aatgaaaggc ttccaattgc aatttgtctt
    11281 gggaacgatc cggttctaag cttcatggct agtacaccaa ttgcatatgt acaatcagaa
    11341 tatgactttg caggtgctct taaaggagaa ccgatagaac ttacaaaaac tgaaaatagc
    11401 aaccttgata ttccagctcg ttcagaagtt atacttgaag gttatattga accaagggtt
    11461 agagaaatcg aaggaccatt cggtgaattc ccaggaagtt attcgggcgc acgtcttcaa
    11521 ccaattgtga aaataacaaa gattacacat cgtaaaaatc ctatatttga aaacttgtat
    11581 cttggaatgc cttggacaga ggttgactac ttaatcgcgc ttaacacaag tattcctctt
    11641 tatgatcaat taaagagaga cttcccagaa gtacaagccg taaatgctat gtatacacat
    11701 ggtataggtg caattgtatc tacaaaatct cgttttggag ggtatggaaa agctgttgca
    11761 atgagacttt tatcaactcc tcacggaatg tcatatacaa agattgttat tgttgtagat
    11821 gaattcgtag atccatttaa cttagaacaa gtaatgtggg ctcttacaac aagagtacgt
    11881 ccagataaag atgtattcaa agttccatac gctccaggta tgctactaga tccatcttca
    11941 gagcctgcag gaatgcatac taaattggtt attgatgcaa caacgccagt agcacctgat
    12001 tttggaagag atacagagct tttaggaagt ccaatagggg tagaaaaatg gacaaaaatt
    12061 cttagagatt tagtaaaaga aggaggcaac aaataatgaa atgtcctaga tgtgattcgg
    12121 aattagtaag cgtaatggta aaatcaccag ttggtaatgc atgggaagta tatttatgtg
    12181 atacatgcaa attctcatgg agaagtacag agggtgaaaa tataacggac ccagaacaat
    12241 atgataaaag gttcaaatta aattcagaag aatttaataa attagatcaa attcctcctg
    12301 tcccaccatt gctaaaaaag aaataatgat ttgtaagttt aacaatatag ggattctttt
    12361 gcaatgaaat tgtaaatgca ccaataatga gctatattag gatgagtcaa aataaattga
    12421 aaaataatta cagagtttgg gagtgttatt attgagttaa gaaagacctg tttctaagaa
    12481 ttattcttga atcaagtctt ttttgttttg aagggagata tacatgtaga actttcaact
    12541 ttagaggatt tacgggaatg ttaataatac aaaaattttg tctgttcaga attgtattat
    12601 tgaataaata atacagttat atgtctttag aaattacgat atgtaaatat atggaaaaga
    12661 cgtgaaatga taacgtttta tctcgcttaa tctaatttta ttgcatatag ggattgtttt
    12721 tatagtatac agtgctatga tactagcata taatgattta ctatttaatc atttgacgat
    12781 gaaatgtctt cagcattaaa tctaaagtat tcattataga ggataacaat aggttctaat
    12841 atttactgat tttagagtat ataagttgca ataaaaactt tttatttgac tgctttgtat
    12901 aggtttaaag ctaaataata aatataaatt atttgttgag acttatattc attgagtgat
    12961 taaaaaataa aaagtggtgg atgaaattaa aaaatgctaa ttacagtctt gaacattgtt
    13021 gtatataagt gattagaatc tatattgtta aaaaaataac aatgtttttt attttaggaa
    13081 ctatggtatt aaaagatctt caagtttttt tcaaaatcag ttttgaacct attgaaatat
    13141 gattcatatt tagccttaaa aagttagata aactaaggct tgaggaattc cacaaacaga
    13201 taaattaata tttattaaaa atttaggagg ggaaaattat ggaacagtta ggagtatttg
    13261 aaacagcaac agaggcatgc gtagcagcta cagttgcaca aaaggagcta gtgctcaaat
    13321 atacacttga ggacagggat cgttttatag gtaatatccg taagaatatt attggtaaca
    13381 tggaaatgct tgctgagatg gaatttgatg agacaggtta tggcagatta gaagataaat
    13441 tagcaaagaa tacaggtgcg gttatgctat ctcagggtac agaagctatt ccacaaaata
    13501 tgtatgcctc tgataaggga cttacagtag aatattatgc accatttggt gtcgtaggtg
    13561 ctgttacacc tgtaacgaat cctgttgcta cagttgtagg aaatggtatt gcgaatgtcg
    13621 cagcaggaaa tgcaattgta tttaatgctc atccttcagc caagaagact tcagcaaggg
    13681 cagtacattt aataaacaaa gctgttattg aagttggtgg acctggtaat ttatttacaa
    13741 tgccagcaga acctacttta gattcactta atgaaattat ggcgtatcca tcagttaaat
    13801 tattgatagg aacaggtggg cctggaatgg ttaaaactct gatgtgttca ggtaagaagg
    13861 ttattgcggc tggggcaggt aatccaccat caattattga tgaaacagta gatttagcaa
    13921 aagcagcagc aggaatttat gagtcagctt cttttgataa caatctgctt tgcatagcag
    13981 aaaaagagtt gtttgtagtt gatactatat ttgatgagtt tatgaaaagg ttagaatcag
    14041 taggagctta tcgcgtaaat acggaagaag gaaaaagatt aacagatatt tgtgttgtaa
    14101 aagcatcagg tggtagttat gctgcgaata aaaagtatgt aggtaagtgt gcaaatataa
    14161 ttttaaaggc ggcaggtata aaaattaata atgatcctag aatggttatt tttgaagcac
    14221 agaatgatga taaattagtt catacggagc agatgatgcc tattatacct gttgttaggt
    14281 gtaaaaattt tgaagaagca gttgaaagag cagttgcagc agagcatgat tgcaagcatt
    14341 ctgcatctat ttggtcaaat gatataaaca gagtaactgc ttttggaaaa gttataaata
    14401 caactatttt tgttcaaaat ggagggacaa tggcagcatt tggtattgga ggcactggaa
    14461 ctaatgcacc gactattgct acaccaacag gtgaaggtgt aacaggaccc caatcattcg
    14521 taagaagaag gaggttctgc atggcaggtg gcggaaatta ccttttataa caggataaat
    14581 aataaagaaa tgctctgtta aaaggttatc aatatacaag gagtgatacg aaaatgcaga
    14641 ttgagagttt tcaagatttg gttaagaatg ctcaaagtat agaaaagaaa agtaggattg
    14701 cagtggtggc tgctcatgat aagcacactc tacaatctat agtgaaagcc aaaaaagata
    14761 atttaataat tcctatattg ataggaaatg aaatggtaat tgtaaagatg ttgatagaat
    14821 taggagaaga ttctagagaa tataaaattg tacacgcaag aaatattgat gaatgtttgg
    14881 ttattgcagt tgaaatgatt cataaacaca ttgcagattt acttatgaaa gggaaacttg
    14941 aaacgtctac tatgatgaaa gtaatcttaa aaaaagagaa tgatttgaaa aaagatagaa
    15001 ctatgtccgt agtcggcttt tttgaaactg agaagtatca taaattgctt tctgtaagtg
    15061 atgtggcagt taatatatat ccggatgtgg aaagaaagaa ggatattttg ttaaatgcag
    15121 taaagatttt aaatttaatg ggagtagaaa atcccaaggt agctcttttg acagcaaccg
    15181 aaaatataaa tcctaagatg cctgaaactg agcatgcaaa tgatttaaag cagatgaaca
    15241 aaaatggaga gatacagggg tgcattgtgg aaggacctat ttcctttgac ttggcaacca
    15301 gcagggaagc aacacgaata aagggatacg aaagtcaagt tgcaggagat gcagatttat
    15361 tattgatgcc agatcttgtt tctgcaaatg tattaggaaa atgtttgaca ggatttgcag
    15421 gtgcgcagac tgctggttta ttagttggcg caaaggttcc aataatatta acatctcgtt
    15481 ctgccgaagc ttctgataaa tattattcaa ttgcacttgc tgcctatgtt gcacaaaatt
    15541 attaatttag gaaagaagtg gtggatatag tgaaaactta cgttattcta gctgtaaata
    15601 caggatcaac atctacaaag attgctgtat ttgagaatga aaaagaagtg tttaataaaa
    15661 atataagcca tgatattgat aaattaaaag aatttaaaca gatacaggat caattaggat
    15721 atagaaaaga aatagttgaa caggaactta aggctcatag aatttctata aagaatattg
    15781 agatttttgt aggaagaggg ggcggtttgg taccaattaa aggtgggacg tatttagtaa
    15841 atagtaaact tattgaacat gctagcaaag gaatgtcagg acagcaccca gcacagctgg
    15901 catctcagat ctgtaatatc tttgtaaaaa agtatggtgg aagagcttat gttgtaaatc
    15961 cgcccgatgt tgatgaattt gaagaaatcg caagaattac tggattatat ggtgtataca
    16021 gagaaagtaa agttcatgcg ctaaatcaaa aggaagttgc attgagatat tgtaatacaa
    16081 ataataaaaa atatgaaaat agtaaactta tagtttgtca tattggaggg ggaatttcag
    16141 tgacagccca caataatggc aggatggtag attctaatga tattattaat ggtgatggac
    16201 ctatgacgcc tacaagagct ggtgcattac ctattacaaa ggtagtaaga atgtgttata
    16261 gtggaaggtt tacagaaaaa gagctgtaca ataaattgac taaagaaagt ggtttgattg
    16321 atcatctagg aacatcagat attagaaaaa ttgaaaagcg tattatgcta ggtgatagat
    16381 atgcaaaact ggtatataat gcaatgattt atcaaattgg gaaaagtgta ggagcagctg
    16441 cttgtgtttt aaaaggaaaa gtagatgcaa ttattttaac cggtggaata gcgaacagtg
    16501 actatttggt gtcaaagctg gatgaatata ttagctggat ttctaagatc aaggttatac
    16561 ctggagaatt tgaaatggaa gcgctggcag ccggggctct tagagtagtg cgtggtgagg
    16621 aagaggctat attatacaca gggcatccta tttggagtgg agttactgct taaaaattgt
    16681 taaaaagata ttgatatttc atgattatat ttagacgctt tttagtatat ttgtaggaaa
    16741 ttaagaggga catttggaac tttgtggaat attaacatta agatttattt ttgataatta
    16801 atagtagatg tagggatggc aacaaaaaca ttatttttat ttagtggcaa tagggtcact
    16861 cacattttct acatttcctg ttttcgttac ttttcttgaa tcatgttttt tttaagagaa
    16921 aatcaagttg tcagatattg tgattgcaac tattacattc ttgggtgttg tgtttgttat
    16981 tccgaagttt gaattcggaa gtaatctaac tcaaggtgtt gttttttatt caaccattaa
    17041 atctaaataa ttcatattat tgttggttaa tgctttaatt taaaaatgaa caacttatta
    17101 aacaccatat tattcacaaa aattttacgg tgttttttat atcgtaatat ttttattgca
    17161 ttataaaagc aatccgttaa ttgattttat tgaatcgctt ttttcatgct aatttatcta
    17221 gtctaggtgc ggatattaat tggttttaag aatttagtca atctactcaa cttacttaga
    17281 gtaataataa aagtttaaaa ttaaagacat tgataaaagt gtatttatac aatatatcag
    17341 tataagtaca ctttttttga ttgagaatat aataaggcct aagaaagata aatacatttt
    17401 acatagtatt tacgctcctt ttaatagttt ttagatagaa attttaaatt tgtcattgaa
    17461 aacgtaacac aattttgaag ttgtttaaat tgaaaaggtt ttatacatac tataagataa
    17521 taactgaaag aactaatgtt aaagtatata aataaaataa atggaggttt tattatggaa
    17581 actaacaaat cgtctcttaa aggaaacgta caaaggttag gtagtttttt aagtggtatg
    17641 gtattaccta atattggcgc atttattgct tgggggttaa ttacagcttt attcattcca
    17701 acagggtgga tgccaaatga atatttgggc aagctagtag ggcctatgat aacgttctta
    17761 ctaccattac ttattgggtt cacaggtggt aaaatggttt acggacatag aggtggagtt
    17821 gttggtgcaa tagcaacagc aggggttata ataggtgctt ctattccgat gttcttagga
    17881 gcaatgatca tggggccagt tggtgggtac gtaatcaaaa aatttgataa attaatagaa
    17941 gataaagtac caacaggttt tgaaatgcta gttaacaact tttcagctgg aatcattggt
    18001 ggaattgtag caattttagc ctatacatgt attgaaccag tagtttccac attttcaaat
    18061 acattgggaa gtttggctac tatagttact aatttagggc ttttaccatt aatagatata
    18121 tttatagaac ctgctaagat attattccta aataatgcaa ttaatcacgg aatattaact
    18181 cctcttggag tacaacaagc agcggatgca ggtaaatcaa tattcttctt acttgaagca
    18241 aatccaggac caggtcttgg tatactttta gcttattctt tatatggaaa aggaaatgca
    18301 aaacaatcag ctccaggagc tataattatt cacttccttg gaggaataca tgaaatatac
    18361 ttcccataca ttttaatgaa accaatatta atattagcag caatagctgg tggaatatct
    18421 gcagatttag tatttgtgtt aactcatgca gggcttagag cagcatcttc tccaggaagt
    18481 atatttgcaa tattagctat gacagcaagt gattcatatg taggtgttat aggaggtgtt
    18541 gcagtaggcg caatagtgtc tttcttagta ggttcattga ttcttaaagc atcaaaagat
    18601 aatgcagaag aagaaaactt cgatgacgca caagctaaaa taaaagatat gaaggcagaa
    18661 agtaaaggtg caaaggttga agaagctaaa gtcagcttat caaaaactga tgttaagatg
    18721 atagtttttg cttgtgatgc aggcatggga tcttctgcaa tgggagaatc tattctaaag
    18781 aaagcattaa aagatgctgg aattactggt attgatgtaa agcactcatc agttgatagt
    18841 attccgcagg aagctaatgt gatatttact caagaaaact taattgagag agcaagaagt
    18901 tcagcaaata atgctgctag cataattaca attaaaaatt tcttggatcg ttctaaatat
    18961 gatgaattta taaatacatt aaaataatac ataagtttat cattgtcaaa tataaaaaat
    19021 tactagtaat aaagggcaat tggtttaatg attgtccttt attgtaataa gtgtaggcta
    19081 gagaaaaaaa tgatatcttt aagatattat ttttttaaga atgatagtta aaaaaatatc
    19141 aaacaattgt ggatatatga aggtatttat aaatgagtac aaaaaagaaa aggtcattaa
    19201 catagatata aatttataag aatacaaaaa ataaattaga tgtcttaaat taaatactta
    19261 atagcactta tcaagaaagg aaaggcaaat gcttttcctt taaaaataaa aaagattgat
    19321 taatatttaa caagcaatct tttaggacta atataaatat tgattattaa agatgaaaag
    19381 tcgggagtta aatacccatt ggctgattat gaactaaccc cggatatggc aatagttgat
    19441 gttgaactta tgattaatat gccaaagaat ttaacggcag cttcaggaat agatgcatta
    19501 attcacgcta tagaagcata cgtgtcagta cttgcatcag aatatactaa tggattagca
    19561 cttgaagcaa taaggttaat attcaagtat ttaccacagg catacgagga aggcacaact
    19621 aatgtgaagg caagagaaaa aatggctcat gcatcaacta tagcaggcat ggcatttgct
    19681 aatgcattct taggagtatg tcactcaatg gctcataaat taggagcaga acatcacata
    19741 cctcacggtg ttgctaatgc actattaatt aatgaagtaa taagatttaa tgcggtggac
    19801 aatccattaa aacaaacagc atatccacaa tataaatatc caaatgttaa aacaagatat
    19861 gctagaattg cagattactt aaacttgggt ggaaaaacag aagatgaaaa attagaatta
    19921 ttaattaaag ctatagatga attaaaagaa aagttagatt taccaaaaaa cattaaagaa
    19981 gctggagtaa cagaaaagaa attctataga accttagatg aaatgtcaga gcaggctttt
    20041 gatgatcaat gtacaggagc aaatccgaga tatccattaa taaaggaaat aaagcagatg
    20101 tttataaatg cttatgatgc agcagaataa ataggcggta ttttatataa atagtagttt
    20161 ggtaaatatt aattgattta caaaactact ctatgtagta gtttttattt aaaaggatgg
    20221 atagtgacta taagattttt ataactttaa atttgtcatt agaaacgtac cacaaatttg
    20281 aacttgttta aattgaaacc gtatttagga tgatttaata tataaagtga aggaggcaat
    20341 attaattaac attgatgtag ttgcttaaaa attaatcaag actcaagtta ttttagcagt
    20401 atggtctcca aatgaatgtt gactaaaatg atataaaaac ttgaaataag tctgtgtcaa
    20461 gttaatgatt ttgtttctaa tggatgcatg gaattttttg tgattggaaa atctattttt
    20521 aaagaaacta aaaaattaca gccaataatg attcaagcat tcatgaaaat agaatattac
    20581 aaatatgatc agtttgtgaa tataaaaaat aaaaagtaag tcaggtgata tattatgaat
    20641 agtttaacgc cgagacagca atttatattg aacacagtgt taaatgaaga aacttttaat
    20701 attaagcgac ttcataaaga tcttgatatc agtgaaagaa ctattttaag agaaatttct
    20761 tctattaata aaaggttgaa aaaaaatagt gtgactatat ttaatgatga aaatatgaat
    20821 ttaagcattt caggtaaaaa agaaaatata gaagatataa agaaatcatt ggaaatagtt
    20881 ccgattccgt ggctgtttag caaagagcaa agacaagtag taattatatg tgaattgtta
    20941 gttagtaagg aaccattaaa ggcttcatat ttttctcaca aatttaatgt tgtaatggga
    21001 agcataagtc tagatataga tagtattgaa gaaaggctta tttctaagaa cttatgcatt
    21061 attaggaaga gaagttatgg cataagtatt caaggatcag aatggaataa aagaaatgca
    21121 ttagtggaat tgatttttga atttaaacca tttgaggatc tattagcatt cctttatgat
    21181 gaaaaagttg atcctataat taagaatttt tttaatatta tttttggaag tgaagatatt
    21241 aaattaataa aagatatatt aaaagataat gatttaggtt accttaaggg aaatgatgta
    21301 aagtatttca gtctatttat ccaattatta ctatcaataa aaaagacaaa aaatggagaa
    21361 aatatatatt tacctaacca tattaaagaa aatatcttat cattagagga atataagaaa
    21421 atacagtact taggtgaatt attacaagaa aaaaatatac atataactga agatgaactt
    21481 gtttatttgt gcttgtactt aagtgactat aaatattaca ttagtaatga gcaatttgta
    21541 gaatcagaca ttaattatga gaatatagct aaggaagtta cggaagaagt atcaaaaaaa
    21601 atacatgtta atattgcaga ggatgggcaa ttaataaagg atttggccca acattttaga
    21661 caaacatttt atatgttaaa tttaggatta aaagtaataa atccattaat taatgaaata
    21721 aaagagcatt atacaaattt atattcagtt ataaaaaata cttgtagatt aatattttct
    21781 agatataatt taaaaattcc accagaagaa gcgggatata taaccatgca tattgctgtt
    21841 gcaatacaaa agcagcaagc aatgttagga aatattaaag tgcttgtaat atgtccaagt
    21901 ggtataggaa gctcaagaat cttatgtaat aaaataaaag aactttttag cgaaatagga
    21961 attattgatg tagtatcact acacgacatt aataatacta tcgataaaaa taattatgat
    22021 ttgatattgt caacagtacc agtaaactta aagatgaaag ataatttaat tgtaatttca
    22081 cattttatga cggaaa
//
