LOCUS       NC_020291.1            25385 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_020291.1 Clostridium saccharoperbutylacetonicum N1-4(HMT),
            complete sequence.
ACCESSION   NC_020291
VERSION     NC_020291.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:47:19
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2290063
            Orig. end    :: 2315448
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25385
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2300063:2305448]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15385
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..25385
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25385
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="acetate2butyrate"
                     /region_number="6"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             681..1136
                     /locus_tag="ctg1_2012"
                     /transl_table=11
                     /translation="MSFKEIIKNVIGNKGDNKMKEVVEFLQANPVQYLATVGRDGKAKC
                     RPFMFSLEQEGKLWFCTNNTKDVYKDLQENPELEVSISSPEYAWIRLNGKAVFENNMAV
                     KEACMLNPIVKGQYNEASNPIFEVFYLENAKAVIADFSGNPPKEYNL"
     CDS             1355..2422
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2013"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.7e-06, bitscore:
                     26.1, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRIFKKLISFIIVLVITNSILIYCSAKSTNTISAITSNRPVKVGV
                     LLNNFYNSYNLSIKKSLEDIQKEKKNEIQFIFFDGESNPAKQSVIFNNMLQNNYNLLLI
                     STVDKKTPEMIEDFVDKAKQKDIPLIFFNIRPDNLDIIKKYQKAIAINTDSMQAGILQG
                     KMIADYWNENKEMDKNGDGIMQYILIKGQPESYLTETRSNYSISTINEAGIKTQELAAV
                     SANWDEDLAKSVMESLFLKYDGSIEAIIANSDSMAIGAVKALQTYGYNLGDKTKTIPIF
                     GIHATPEVQELIKKGFMAGSVLQDTRELADAFYSVGMNLILGKDPLEGTNYKFDKTGEI
                     INIPFHEYVYQKEDK"
     CDS             complement(2487..2876)
                     /locus_tag="ctg1_2014"
                     /transl_table=11
                     /translation="MIEKILTMKLFKDKYGVCRLTRNESIPKWAQDSDFFSITKTSDEL
                     SIVCLEDSIPSEIKCERDWRILKIEGPLDFSLIGILASISTILAQKGISIFAISTYDTD
                     YILVKNKDLDNAVESLIKERYEVLD"
     CDS             3398..3583
                     /locus_tag="ctg1_2015"
                     /transl_table=11
                     /translation="MDEKKILELLFNTFVKMCDYIETTDEIGCIKCPCKEECILKGNNT
                     DFKYFKPVVESIKKKL"
     CDS             3604..3912
                     /locus_tag="ctg1_2016"
                     /transl_table=11
                     /translation="MKKIMNEQLIYEILSVVEEIPEGKVATYGQIASLIGRDKNARLVG
                     KVLSQSEFYGEYPCHRVVNHSGRLAPGWKEQRFLLLEEGVSFKDENHVDMKENKWDC"
     CDS             4046..5770
                     /locus_tag="ctg1_2017"
                     /transl_table=11
                     /translation="MVKEALFLNYFNDLKIILDNVFNEIVVVDNNNKIIFINRAASILF
                     GIDSKNSLGKAFNELIHNVELSNFLTNKKEEVKKSIVVNNLNLSLSIMSLIEDKDVVGS
                     ILIFSNITNYNELLQKLDKERDSREILNTVIETAYDGMVIIDKKGIITMMSKAYTDFLG
                     IRREDAIGKHVNEVIENTRMPIVLESGKEEVAQLHKIKGNYMIASRIPIIKNGEIIGVV
                     GKVLFRNVKELNSLYKKITVIEKELANYKSRLKEFNTASYSLENIIGESDSILLAKDIV
                     KKAAHTSSNVLILGESGTGKEIFAHAIHSESNRYEGPFVKVNCAAIPSDLLESELFGYE
                     AGAFTGARKEGKIGKFEIANEGTIFLDEIGDMPLHMQVKLLRVIQEREVEKVGGVATKK
                     INIRIIAATNRNLEKLVSEGKFREDLYYRLNVVTIEIPPLRERGNDIILISNHLIKKLS
                     MNLDKKVKGISKEAEHYLKIYEWKGNVRELENILERAINIMGDSDIIDVDDLPKEITGK
                     KAAIIPKRLQDILEESEKNAIILALRAAEGNKTKAAKILEIGRTSLYEKMEKHKIKM"
     CDS             6051..7595
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_trans_230_acto"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2018"
                     /sec_met_domain="CoA_trans_230_acto (E-value: 5.5e-105,
                     bitscore: 348.3, seeds: 30, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKIMSVEQAISLIKNGDTVAVGGFIGIGHPEEITKRIKEIYLEE
                     GKPNKLTLVYAAGQGDGKEKGLNHFGQEGLLSKVIGGHWGLAPKIQKLAIENKIKAYNL
                     PQGVISSLYRDIAAGKPGTITHVGLKTFVDPRVEGGKLNSCTTEDVVKMIEIDGKEYLY
                     YKAFPINVAIVRATYADEEGNASLQKEAATLDGLAMAQAAKNSGGKVILQVEKIVSKGT
                     LDPKLVKIPGILVDAVVVASAENQMQTFGESFNPAFCGEIKMPANTIKCLPMDERKIIA
                     RRCAMELIPNAITNLGIGMPEGISMVANEEHIGDSMRLTIESGPIGGIPAGGLSFGAAI
                     NPDSIIDQSSQFDFYDGGGLDIAFLGLAQCDEKGNINVSKFGPKIAGCGGFINITQNAK
                     KVIFCGTFTVGGLKTNIFEGKLIIENEGKSKKFIKDVEQITFSGDYAKDVKQVVLYITE
                     RAVFRLTSAGVELEEIAPGVDLQKDILDQMDFKPIISEELKTMDKRIFEDKLMNLK"
     CDS             7674..9068
                     /locus_tag="ctg1_2019"
                     /transl_table=11
                     /translation="MAVIGILLSLILLMVMAYRGFSVIVFAPIFAIAAAIFSGMAVMPT
                     YTEVFLPNLGNYVKVYFPFFLLGAVFGKVMEQSGAAKSIAKFIVEKLGKKRAMLSVILS
                     AAILTYGGVSLFVVAFAVYPFAASVFKEADIPKRLVPATIAVGAFTFTMDALPGTPQIQ
                     NSIPMKFFNTDLYAAPVFGTLGAIIVLVCGVSYLEWCKRKAQAKGEGYGENHKNEPVLV
                     EDGSLPNPFISVLPLISVLGLTLVLQKLVFPKWDIVSWVTKAPYNIPEASVVGSMNNWA
                     LMIALVFGILLAISINPKRMKGNLASAINAGAIGSLLAVMNTASEVGFGNVIKTLPGFQ
                     SIAHALTNINPDGSPLLSEAVTVNVLSGVTGSASGGMSIALDTFGKEYLNWANSVGIDP
                     QLLHRVAAMASGGMDTLPHNGAVITLLGIAGLTHKQSYKDIFVITCIKTGSVFILIALQ
                     SILHFI"
     CDS             9151..9567
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MaoC_dehydratas"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2020"
                     /sec_met_domain="MaoC_dehydratas (E-value: 7e-25, bitscore:
                     85.4, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGLTIKELNIGDKASFQKTITETDVYLYAGITGDLNPAHINQVE
                     AEKTMFQGRIAHGMLTAGLVSAVLGMQLPGPGSIYLGQELKFVAPVKIGDTIKAEVEVI
                     EKFEDKNRIKLSTICTNQNGVEVLVGVANIMPPK"
     CDS             10001..10846
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2021"
                     /sec_met_domain="HCDH (E-value: 3e-36, bitscore: 122.3,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 4.4e-67, bitscore: 223.8,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIFVLGAGTMGAGIVQIFAEAGYQVIMRDIEESFVQKGITNITK
                     NLDKAVKKEKITEESKNEVLGRIIATTDINLAKDADLVIEAAIENMNIKKKIFAELDDV
                     CKPETILATNTSSLSITDVASATKRPDKVIGMHFFNPVPVMKLVEVITGMATSAETKDT
                     VIEITKKVGKDPVEVKEAPGFVVNRILIPMINEAVGILADNVATAEDIDIAMKLGANHP
                     MGPLALADLIGNDVCLAIMEILYIEFGDPKYRPNPMLRKMVRAGYLGRKTGKGFYDYSK
                     "
     CDS             10950..12134
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2022"
                     /sec_met_domain="Thiolase_N (E-value: 5.8e-111, bitscore:
                     368.4, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 2.5e-52, bitscore:
                     174.1, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEVVIASAVRTALGSFGGSLKDMPAVDLGAIVIKEALSRAGVNP
                     EIVDEVIMGNVLQAGLGQNPARQSAMKAGIPLEVSSFTINKVCGSGLRAVSLACQMILS
                     GYNDIVVAGGMESMSRAPYVLNDARWGQRMNDGKLIDSMINDGLLDAFNKYHMGITAEN
                     IAEQWNITREMQDEFALRSQLNAEAAIKAGKFKDEIVPVAIPQRKGDPKIFDTDEFPRL
                     GSTKEGLEKLKPAFKKDGTVTAGNASGINDGAAAFVIMSAEKAEELGIKPLAKIVSFAS
                     KGVEPSIMGYGPVPTVKEALKRASLTIEDIDLIEANEAFASQCLSVAKDLEFDINKVNV
                     NGGAIALGHPVGASGARILVTLIHEMIKRDCKKGLATLCIGGGQGTAVIIERCN"
     CDS             12350..13489
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2023"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.7e-52, bitscore:
                     174.1, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.1e-27, bitscore:
                     92.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.4e-34, bitscore:
                     117.5, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFKLTREQELVQQMVREFAVNEVKPIAAEIDETERFPMENVEIM
                     AKLGMMGIPFSKEFGGAGGDVLSYIIAVEELSKVCGTTGVILSAHTSLCASVINENGTK
                     EQREKYLPDLCSGKKIGAFGLTEPGAGTDAAGQQTTAVLEGDHYVLNGSKIFITNGGVA
                     ETFIIFAMTDKSKGTKGISAFIVEKSFPGFSIGKLENKMGIRASSTTELVMENCIVPKE
                     NLLSQEGKGFGIAMKTLDGGRIGIAAKALGIAEGAFEEAVNYMKERKQFGKPLSAFQGL
                     QWYIAEMDVKIQAAKYLVYLAATKKQAGEPYSVDAARAKLFAAEVAMEVTTKAVQIFGG
                     YGYTKEYPVERMMRDAKICEIYEGTSEVQKMVIAGSILR"
     CDS             13503..14282
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 167.1;
                     E-value: 1.3e-51)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2024"
                     /sec_met_domain="ETF (E-value: 1.2e-49, bitscore: 167.1,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVVCVKQVPDTTAVKIDPKTGTLIRDGVPSIMNPEDKHALEGA
                     LQLKEQVGGKVTVVSMGLPMAKAVLREALCMGADEAILLTDRAMGGADTLATSKAIAGV
                     IAKLDYDLVFAGRQAIDGDTAQVGPEIAEHLNIPQVTYVQDVKVEEKSLIVSRALEDGH
                     QVIEVKTPCLLTAIEELNETRYMNVAKIFETSDDEIKVMSAADIDVDVAELGLKGSPTK
                     VKKSMTKEVKGAGEIVREAPKNAAYYVVGKLKEKHYI"
     CDS             14378..15385
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 175;
                     E-value: 4.7e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2025"
                     /sec_met_domain="ETF (E-value: 4.4e-52, bitscore: 175.0,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 4.2e-37, bitscore:
                     124.5, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIADYKGVWVFAEQREGQLQKVSLELLGEGRRIADELGVKLTAL
                     LLGNNIETLAKTLAEHGADEVLVADDKNLEHYTTEGYTKVICDLATERKPGILFVGATF
                     IGRDLGPRIAARLSTGLTADCTSLDVDVTNGDLLATRPAFGGNLMATIACPDHRPQMAT
                     VRPGVFAKITTDPSKCNIEKVNVTLDDSDIRTKVLETIKSKKDIVDIAEADFIVAGGRG
                     VGNKENFTLLKELADALGGTVAGSRAAVEKGWIDGAYQVGQTGKTVKPQIYIACGISGA
                     IQHVAGMQDSELIIAVNKDDSAPIMKIADYAIVGDLTKVVPELIAQVKEIKSAE"
     CDS             15578..17341
                     /locus_tag="ctg1_2026"
                     /transl_table=11
                     /translation="MLEKSVKKSTRFAIKAKLILVMLLLLSIPVLILGLISYYVAKAEL
                     ENNGKILLKNSVEMTLQAIDNNQKLVDQGKLSLEEAQEKVKEYMLGKKQADGTRPINKN
                     LSLGQNGYLLAYTQDGVEAVHPSLEGKNVLDSKDKKNGNLFVKDQIKIANDGGGYLTYY
                     WTIPNSDSIADKITYQKTDPHWGWVICAGTYMNDFNVGSNKIFITTIIILLVVFILGST
                     IIMIFSKHISTPIKEISNAVDAVALGNLNIERLKIKNRDEIGNLSDSFNVMVKNVNSFI
                     SSVKNSVDIVFDSSRLLDEIVYENTASINEVASSVEEIAKGSSQQARETENGVLRVKNL
                     SEKIDLVTRLTVETNDIAIETADISHKGLNAIELLSKKSDENNTATEKTSDIIMEVDKN
                     SVEIGVITEAISQISEQTNLLSLNAAIEAARAGEQGKGFAVVAEEIRKLASQSSRSAEK
                     VKELIIGIQDKSKIAVKTIESGKIIAKEQSKSVLEAKYIFSEILKSVEKITDDLKNLKT
                     YSLEMENEKDELIDVLETLSASTEENSAATEQISATSEQQLASINQVAKHTQDLTQLAE
                     KLKEAVGAFQI"
     CDS             17857..18525
                     /locus_tag="ctg1_2027"
                     /transl_table=11
                     /translation="MDVRDISTESRIERKKRETREKIVKISMNLFQDQGFNNTTMEQIA
                     EKTDIARKTLYNYFPVKEAIVDEYVRGISQKLAGENLETIWNLPNTKSRLVASLNHTYS
                     WVEGNKEIMGICMNYRLRNMCNDSKTQNAETGTQSILNQIISRGQETGEIRKDISVKLL
                     VTHINILRSAMTFEWVNSTSRFELHDEIAKLVDLFLYGADNRLDSSKKSELDNIISQEE
                     "
     CDS             18531..21182
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2028"
                     /sec_met_domain="PPDK_N (E-value: 3.9e-79, bitscore: 264.7,
                     seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYFFTWKEAFKSDASLVGGKGWNLGRLDRYGFSVPQGVVLIAKA
                     YDEYIKYNQFDKVISNLSSIIHLNNLDEGNVKDGLDQLRKKIMNGSMPPAIVEELSGLL
                     NSSGKLKKSWAVRSSAVAEDSVKASFAGIHDSFLNVCGLEEILSAVKECYASLWSPRAV
                     AYRRNMNINDDAATMAVVVMEMVEAQAAGVGFTCDVQTGRQDVMIINANFGLGESVVNG
                     AVEPDTYYLEAETLNSEAKLIQRKIGSRQGMTVLNKEGGTKLIPIDSAVSQVLSDQNVK
                     KLGRLLQRVFDALGNSEQHQDVEWVYNGRDFVLVQARPVTILPRKTFPALQEQNDVWSN
                     GNYRDSVPMVQSPLNRRLMKNIIDIIHHTSFTSLGYKLPVGIQFSKFYNGRLYCNLSAY
                     QWGLYASMGGRPEGFNDFWGGHQPAINIGDQKPEPGFEDRAKKFSELVNEARKNAPKIW
                     DEVSTSIQKITGSRLETWKDQDFIAGYDELGQIAGMLAKEFNFLAAVGSMPVFMLIQSL
                     NKYFEGRELMMLNALMIGGTDGITSAEHGYRLVELAEIARKDVDAAKYLSEISFDALGW
                     RELPDNSPFKKAFCEFVKEYGHRAVYELDIINPRWNEEQTYLLGIIQSTVNIADISKLR
                     KEQKEKREQVWKEIKDKVLDSEQIAIRNLVKECQIGAGVREETKSVLAEVMEAYRIIAK
                     KLGFRFYERNLIKEEEDIFFCTWSEIFSVLNGEWNGIGLQALIDMRKKWKKEMELLAPP
                     DVILGETPRFEKQVSCISSNYLEGVPVAAGKASGLARLIKHPDEGVRLQPEEIMVVPST
                     DPGWTPLFLKARAVVMETGGFLSHGAIVAREYGIPAVVNVPGVMDIIKDGWTISVDGNN
                     GKIFFDDKDIKI"
     CDS             21247..21807
                     /locus_tag="ctg1_2029"
                     /transl_table=11
                     /translation="MLWNQVRKTYPNKWIVFDSLKQYEENNKLIIEDVAIIEVYEAKAY
                     LALLEESPLTGYAVGKNSGVPRSKIYKVLDSLAMRGDILISHGSTQQYVPIPAKELIKN
                     RRVKAEENFKLAEKSLEQYNQSAKNRENIWNITGHDEILDKVKECIISAKHRILIELWK
                     EEFKELESELKKASDKGVVVTII"
     CDS             complement(22221..23381)
                     /locus_tag="ctg1_2030"
                     /transl_table=11
                     /translation="MVEVQDIFIEYGEDYLNKHKLTLVQHKAMSAIRKCRTSHLGGHVD
                     VCDNCGNTQISYNSCRNRHCPKCQALAKERWIYNQKSNLLNVGYFHVVFTIPDTLNSMV
                     YQNQRQLYTILFKATSETLSELSFDKKYLGAKLGFTSILHTWGQNLMHHPHIHCIVPGG
                     GLSSIGKWISSRKKFFIPVKVLSRKFRGKFLYYLKQLYYENNLEFHGNQNYLSDEIEFE
                     KLLSATYSKEWIVYCKPPFKNAACVVEYLGRYTHRVAISNTRILSIDNGNATFKWRDYK
                     DKNKYKVMTISADEFIRRFLIHILPSGFMKIRHYGLLGNRNKTTKLNICKQLTNTPILL
                     RDKIPILELIKEITGRDLSKCTHCGSNKLNRSITFCNSPPITTKTS"
     CDS             complement(23374..24237)
                     /locus_tag="ctg1_2031"
                     /transl_table=11
                     /translation="MTKEQVLEKLTFDVELRGLSKHTQAEYYTKVKIFQDHFNKPATEL
                     DEKDIRKFLHYLSTEKGLTSGSVNSYNSGLRFLYGVTLNATLNYKQIPRHRRQRKFPEI
                     LTKSEIQSLFDACDNLRDKCILMTLYGAGLRLSEVASLKVTDIDSEKMQLFIRNAKGSK
                     DRYALLSQANLEILRVYWKAYRPKEWLFYSRVNTGTHITSKAVQNIFHKYIEKANISKK
                     VTVHSLRHSFATHLLESGISIFHIKQLLGHSDISSTCFYLHLLKIQSLNVQSPLDFLTE
                     TEKTNG"
     CDS             complement(24810..25319)
                     /locus_tag="ctg1_2032"
                     /transl_table=11
                     /translation="MCTISRKEKEKLVREKDIINAAEKVFTMIGYNGASMEAIAKESQF
                     TRKTIYQYFTDKEDLLFSVIIRGFERLFCTLKNAVVNGNNGIEKLKHLTNAYFQFYKDS
                     PNTLNLMNYIGYIKPTAENSAKRIEFNKVSEQLAQEIAKIIDEGKADGSIRTDFDTMKL
                     THSLNF"
ORIGIN
        1 agcttatggg ctagtagcta cctgacaatt tacaaagggg tcgcaactga tacagcagct
       61 agttttgcta gtgtattttt tataggaatt acggtaggaa gggcacttag tggatttatt
      121 actatgaaac taaatgattt gcagatgata cgacttggtc agggaattat tgcaattggg
      181 attatagtaa tgtttttgcc tatgaacgaa aatgtgtcct tagtaggatt aatattgatt
      241 ggacttggat gtgcaccaat ttatccttgc attatacatt caacacctgc acattttgga
      301 gaggataaat ctcaagcaat aatcggtgtt cagatggcaa gtgcatatgt ggggacttgc
      361 ttaatgcctc caatctttgg attgattgct ggtaatatta atgtaggatt attcccagta
      421 tatctattac ttatacttgt cataatgatt gtaatgagtg aattattaac aaagaaaaca
      481 gctttgagta agtgataagc aaagaattaa tgaaagggag aaatatactc atttatttat
      541 attccaatag tatcttatta gaaactataa atcctcaaag tgcctatgcc actttaaagt
      601 gcttacttca cagtagtaaa ctatgcactt ataataaaaa cataggaagt ggccacttcg
      661 tattataagg aacttataat atgagtttta aagaaataat aaaaaatgtt attggaaata
      721 aaggagataa taaaatgaaa gaagtagtag aatttttaca agcaaatcca gttcaatatt
      781 tagcaacagt tggacgcgat gggaaagcaa aatgccgtcc atttatgttc agtttagagc
      841 aagaaggaaa actatggttt tgtacaaata acacaaaaga tgtgtacaag gatcttcaag
      901 aaaatcctga attagaagta tctatttcaa gtccagaata tgcttggatt agattaaatg
      961 gaaaagctgt atttgaaaac aacatggcag ttaaagaagc ctgtatgcta aatcctatag
     1021 taaagggaca atacaatgaa gcttcaaatc caatttttga agtattctat ttagaaaatg
     1081 caaaagcagt tattgcagat ttctctggta atccaccaaa ggaatataat ttatagtaga
     1141 aacttgaaag tcttaagaat tcttaagact ttttttcata aaagcttaat atttgttttt
     1201 tatatagatt aaagataatg tgattgtaaa attagtgatt aacaaatagt aattatttta
     1261 taaatcgtta taattacctt tgctaaagta cataataagt atgcaataaa attattaatg
     1321 gatatgctaa tggtgattgt atggaggagt tagagtgaga atttttaaaa agctaatatc
     1381 ttttattata gttttagtta taacaaatag tatactaata tattgtagtg caaagagtac
     1441 aaatactata tcagctatta cttcaaatag accagttaag gtaggagtgt tactaaataa
     1501 tttctataat tcgtataact taagtattaa aaaaagtttg gaagatattc aaaaagaaaa
     1561 gaaaaacgaa attcaattta ttttctttga tggagagagt aaccctgcga aacaaagtgt
     1621 aatttttaat aatatgcttc agaataatta taatttatta ttgataagta cggttgataa
     1681 aaaaacacct gaaatgatag aagattttgt tgataaagct aaacagaaag acattccatt
     1741 aatttttttt aatataagac ctgacaattt agacataatt aagaaatatc agaaagccat
     1801 tgctataaat actgattcaa tgcaagctgg tattctacaa ggaaaaatga tagctgatta
     1861 ttggaatgaa aataaagaaa tggacaaaaa tggtgatggt ataatgcaat atatattgat
     1921 aaaagggcaa ccggaaagtt atttgacaga aacaagatca aattattcta tttccactat
     1981 taatgaggca ggaataaaga cacaggaact tgcagcagta agtgcaaatt gggatgagga
     2041 cttagctaaa agtgttatgg aatcattgtt tcttaaatat gacggtagca ttgaagctat
     2101 aattgcaaat agtgattcta tggcaatagg tgctgttaaa gcacttcaga cgtatggata
     2161 taatttaggc gataaaacaa agaccattcc catttttgga attcatgcta caccagaagt
     2221 tcaagaatta ataaaaaagg gttttatggc cggttctgtt ttacaggata ctcgcgaact
     2281 tgcagatgct ttctattctg taggaatgaa tttgatttta ggtaaggacc ctcttgaggg
     2341 tacaaattat aaatttgata aaacaggaga aataattaat ataccatttc atgaatatgt
     2401 gtaccaaaag gaagataaat aatataataa ttttaaaggc ctaacattta tttgaaatgt
     2461 tttggccttt ttatcacgaa attttattaa tctaaaactt catatctttc cttgataagt
     2521 gattctacag cattatctag atctttgttt ttaacaagaa tataatctgt atcataagta
     2581 gaaatggcaa atatgcttat tcctttttgt gctaatattg tactaattga agctaaaatt
     2641 ccaattaaag aaaagtcaag tggtccctca atctttaaga tcctccaatc tctttcgcat
     2701 tttatctcgc taggaatact gtcctcaagg catacaattg ataattcatc agatgttttt
     2761 gttatagaga aaaaatcgct atcttgtgcc catttaggaa ttgattcatt tctagtaagt
     2821 ctgcataccc cgtatttatc cttaaataat ttcattgtta atattttttc tatcatcttt
     2881 aagctttatc ctttctttaa ccagtgaaac ccattaatat tagctagcca tatgtgattt
     2941 aagtttcact atattagttt ttatactata aaataaaaaa gcctcagaaa tattataaaa
     3001 atatctccca ggcttttatc cttccgtgta cacaataaat tgtgcgtttt ctctcggacc
     3061 tgccagttat aaactgcgga accctagaaa actaaattat ataaaatttt gataatttat
     3121 aagctgcaac taataaatgg attctagcat aatatcaaat ttgagtcaag tcgatacact
     3181 ttcatctcaa ataatgaagg ttagagttta tagatatttt taatttttaa aactttactt
     3241 gatgaaatcg atatatatat tagtttatat tagtaatttg ttaggatata atataataaa
     3301 gatttattgt agctattgag gttgttttaa ataaaaattc tgcaagttca tagctaattg
     3361 ctgtttaagc tactataata attgggagaa agttataatg gatgagaaga aaattttaga
     3421 attacttttt aatacttttg ttaaaatgtg tgattatatt gaaacaacag atgaaattgg
     3481 atgtataaaa tgtccttgca aagaagaatg cattttaaaa ggaaataata ctgattttaa
     3541 gtattttaaa cctgttgttg aaagcataaa aaagaaatta taattttcag tgcaggtgaa
     3601 tatatgaaaa agattatgaa tgaacaatta atttatgaaa tactttccgt tgtagaagaa
     3661 attccagaag ggaaagtagc tacatatgga caaattgcta gtcttatagg cagagacaaa
     3721 aatgcaaggc ttgtcgggaa ggttttaagc cagtcagaat tttatgggga atatccatgc
     3781 caccgtgtgg taaatcattc aggaagatta gcaccaggtt ggaaggagca acgatttcta
     3841 ctattagaag aaggtgtatc atttaaagat gagaatcatg ttgatatgaa ggaaaataaa
     3901 tgggattgtt aattttgtaa cagttaaaat tacgtttttt cattctagaa cttatacgca
     3961 gtgaaaattt aaattacttt acttattata ttttatagga ggctatttaa aagcgtaaaa
     4021 cttaaaagga agaaggtact ggtagatggt gaaggaagca ttatttttga actattttaa
     4081 tgacttaaaa ataatactag ataatgtatt taatgaaata gttgtagttg ataataacaa
     4141 taagataatt tttattaata gagctgctag tattctcttt ggaatagata gcaaaaatag
     4201 tttagggaaa gcttttaatg aattaataca taacgttgag ttaagtaact ttttaactaa
     4261 taaaaaagag gaagttaaaa agtctatagt agttaataat ttgaatttgt cgttaagtat
     4321 tatgtctttg attgaagata aggatgtagt aggatcaata ctcattttta gcaatataac
     4381 aaactataat gaattgcttc aaaagcttga taaggaaagg gacagtcgcg aaatattaaa
     4441 tactgtaatt gagacggctt atgatggtat ggtgattatt gacaagaagg gaataatcac
     4501 tatgatgagc aaggcatata ctgatttttt aggaataaga agagaagatg caattggcaa
     4561 acatgtaaat gaagttatag agaatacaag aatgccaata gtacttgaaa gcggtaaaga
     4621 ggaagtagcg cagcttcata agattaaagg aaattatatg atagcgtcaa gaatacctat
     4681 aataaaaaat ggagaaatta ttggggttgt aggaaaagta ttatttagaa atgttaaaga
     4741 actaaatagc ctttacaaaa agataactgt tatagaaaaa gaattagcaa attataaatc
     4801 acggcttaag gaattcaata cagccagcta ttcactagaa aatattatag gagaaagtga
     4861 ttctatcctt ttggctaagg atatagtgaa aaaggctgct catacaagtt cgaatgtgct
     4921 tattttaggg gaaagtggta ctggtaagga aatttttgca catgctatac attcagagag
     4981 taatcgttat gaaggacctt ttgttaaagt taattgtgca gcaattccaa gcgatttgct
     5041 tgaatcagaa ctgtttggtt atgaagccgg agctttcaca ggcgcaagaa aagaagggaa
     5101 aataggaaaa tttgaaattg caaatgaagg tacaatattt ttagatgaga ttggagatat
     5161 gcctcttcat atgcaggtaa agcttttaag agttattcaa gaacgagaag tagagaaagt
     5221 tggtggagtt gcaactaaga agattaacat aagaataatt gctgcaacaa acagaaatct
     5281 tgaaaaatta gtttcagagg gcaagttccg tgaagatctg tattatagac ttaatgttgt
     5341 aacaattgaa attcctcctt tgagagaacg aggcaatgat attatactta tttcaaatca
     5401 tctcattaag aagctttcaa tgaatttaga taagaaagtt aaaggaattt caaaagaggc
     5461 ggaacattat cttaaaatat atgaatggaa aggtaatgtt agagaattag aaaatatact
     5521 agagagagct attaatatta tgggagatag tgacataatt gatgtagatg atttgccgaa
     5581 agaaattaca ggtaaaaaag ctgcaataat tcctaaaagg cttcaggaca ttcttgaaga
     5641 aagcgaaaag aatgctatta ttcttgcact tagggcagca gagggaaata agacaaaagc
     5701 agcaaaaatt ttagagatag gccggactag tttatatgaa aaaatggaaa agcataaaat
     5761 aaaaatgtag ttgtacgaat aaacgtacaa ctaatttttt tctcataaat aattgtatag
     5821 aaatccgaac agtatgtaaa tgtttactta aaaatatgta cggaaatcta tacactaatt
     5881 ttagatatcg cagattttat taatgattca caatggacaa acctcctatt ctaggtctat
     5941 tttatctcta aggctttggc acgagtcttg cttatataaa taagtataag tgaacttatt
     6001 aataaatatt acattcttgt ttttagagta tataaaaagg aggaggaaat atgagcaaga
     6061 taatgtcagt tgagcaagca atctccttaa taaaaaatgg agacacagtt gctgtaggtg
     6121 gttttatagg cattggacac ccagaggaaa ttactaagag gattaaggaa atttatctag
     6181 aggaaggtaa gccaaataag ttaactcttg tttatgcagc aggtcaagga gatggaaaag
     6241 aaaaaggttt aaatcatttt ggccaggaag gtcttctttc taaagtaata ggaggacatt
     6301 gggggttagc tcctaagatt caaaagttag caatcgagaa taagataaag gcttataatc
     6361 ttcctcaagg agttatatcc agtctttata gagatattgc agcaggaaag ccaggaacaa
     6421 ttactcatgt ggggttgaaa acttttgtag atccaagagt tgagggagga aaattaaata
     6481 gctgtactac tgaggatgtt gtgaagatga ttgaaattga tggaaaagag tatctttact
     6541 ataaagcttt tcctataaat gttgcaatag ttagggctac ttatgcagat gaagaaggaa
     6601 atgcaagtct tcaaaaggaa gccgcaacgc ttgatggttt agcaatggct caggctgcaa
     6661 agaattctgg tggaaaagta attcttcagg ttgaaaaaat agtatcaaaa ggaactttag
     6721 atccaaagtt ggtaaagatt ccaggaatcc ttgtggatgc agtagttgta gctagtgcag
     6781 aaaatcaaat gcagaccttt ggtgaaagct ttaatccagc tttctgtgga gaaataaaga
     6841 tgccagctaa tactattaaa tgccttccaa tggatgaaag aaaaataata gctagacgtt
     6901 gcgccatgga gcttatacca aatgcaatca caaatctagg aattggaatg ccagagggaa
     6961 tttccatggt ggcaaatgaa gaacacatag gtgatagcat gagacttaca attgaatcag
     7021 gtccaattgg aggaatacca gctggtggct tgagttttgg agcagctatt aatccagata
     7081 gtataataga tcaatcttct cagtttgatt tttacgatgg tggaggttta gatatagcat
     7141 ttttaggact tgcccagtgt gatgaaaaag gaaatatcaa tgtaagtaaa tttggtccta
     7201 aaatagctgg atgtggagga tttataaata taactcaaaa tgcaaagaaa gttattttct
     7261 gcggaacttt tactgtaggt ggacttaaaa ctaatatttt tgaaggtaag ctaatcattg
     7321 aaaatgaagg taagtcaaag aaatttatca aggatgttga gcaaataact tttagtggag
     7381 attatgcaaa agatgtaaaa caggtagttc tttatataac tgaaagagca gtttttagat
     7441 taactagtgc tggagtggaa ttagaagaaa tagctcctgg agtagattta caaaaagaca
     7501 ttctcgatca aatggatttt aaaccaataa tatcagaaga attaaagaca atggataaaa
     7561 gaatttttga agacaaactt atgaatctta agtaatgtat taatgtaaag aatagctaag
     7621 tatggataaa acggttgata aacccaaata atataataat ggaggtttta tatatggcag
     7681 ttataggtat tttattaagt ttaatattat tgatggtcat ggcttatagg gggttctcag
     7741 ttattgtttt tgcacctata tttgcaattg cagcagctat attctctggg atggcagtta
     7801 tgccaaccta tacggaagta tttctaccta acttggggaa ttatgtaaaa gtttactttc
     7861 catttttctt gttaggtgct gtatttggta aagttatgga gcaatctggt gcagcaaaat
     7921 ctatcgctaa atttatagtt gaaaagttgg gtaaaaagcg tgcaatgtta tctgtaattt
     7981 tatcagcagc cattttaact tatggtggtg taagtctttt cgttgttgcg tttgcagtgt
     8041 atccatttgc agcatcagta tttaaagaag ctgatattcc aaagagactt gttcctgcaa
     8101 ctatcgctgt tggcgctttc acatttacta tggatgcact tccaggaaca cctcaaattc
     8161 aaaactctat accaatgaag ttttttaata cagatcttta tgcagcacct gtatttggaa
     8221 ccttaggtgc gattatcgtt ttagtttgcg gggtatctta tcttgaatgg tgtaaacgta
     8281 aagctcaagc aaagggagaa ggctatgggg aaaatcataa aaatgaacca gtacttgttg
     8341 aagatggaag tttaccaaat ccatttatat cagtattacc attaatatct gtacttggat
     8401 tgactttggt tttacaaaaa ttagtattcc ctaaatggga tatagtttct tgggttacta
     8461 aagcacctta taatattcct gaagcaagtg ttgtaggttc aatgaataac tgggctttaa
     8521 tgattgcact tgtatttggt attcttcttg caatttctat taatccaaag cgtatgaaag
     8581 gtaatttagc ttcagcgatt aatgctggtg caattggatc attattagct gttatgaata
     8641 cagcatcaga agtaggcttt ggtaatgtta taaaaacttt accaggattt caatctatag
     8701 ctcatgcttt aactaacatt aatccagacg gtagtccact actttcagaa gcagttacag
     8761 taaatgtgct ttcaggagtt actggttctg catcaggagg aatgagtata gcactcgata
     8821 cttttggaaa ggaatattta aattgggcaa atagtgttgg aatagatcca caattacttc
     8881 atcgtgttgc tgcaatggca tcaggtggaa tggatacatt acctcacaat ggcgcagtta
     8941 taactttact tggaattgca gggttaactc acaagcaatc atataaagat atttttgtga
     9001 tcacttgtat taagacagga tctgtgttta tattaatagc tttacaaagc atattacatt
     9061 ttatttaata agtatttagt atatcaataa agaaatataa atagttttct attgaatgtt
     9121 ataagtaaat tatacaaggg ggaattgaaa atgaacggat taactataaa agaattaaat
     9181 attggtgata aagcatcttt tcaaaagact attacagaaa ccgatgtata cttatatgct
     9241 ggtataacag gagatttaaa tccagctcat ataaatcaag ttgaggcaga gaagacaatg
     9301 tttcaagggc gaattgccca tggcatgtta acagctggtt tagtatcagc agtacttgga
     9361 atgcaattgc caggaccagg ttcaatatac cttggacaag aacttaaatt tgttgctcct
     9421 gtgaaaatag gagatacaat taaagctgaa gttgaggtta tagagaagtt tgaagataag
     9481 aatagaataa aattaagtac catatgtaca aatcaaaatg gtgttgaagt actggtaggg
     9541 gttgcaaaca taatgccacc taaataacct atttaccaga agagctgaaa ataactctag
     9601 tgtgaaaagg atccactgta gtttgaagca actccagaca taggctaata tgatttggca
     9661 aattatagtt caattatagt tactgtatta cttggagctt ttgcatctac catacctagt
     9721 gcaaaagctc ctgatatagt gagtggaaaa gtggagttgg ataataaatg tgtttaataa
     9781 tacctatatg tcttatatat atcatgaatc agaatttcct tggaaaaaat ttaaatgtag
     9841 tttagtaata aaaattataa aacagtataa ttcataaaaa tgttgtgatc gaaaaataga
     9901 gatcttgcag ttatgttttt tattactaaa tatagacgaa tccaatatat taagtatttg
     9961 tggatatcat aatcttataa cgaaaggaat ggatgttaaa atgaaaatat ttgttttagg
    10021 tgccggaact atgggggctg gaattgtaca gatttttgca gaagcaggtt atcaagtaat
    10081 aatgagagat attgaagaga gctttgttca aaaagggatt acaaacatca caaagaatct
    10141 tgataaagct gttaaaaagg agaagattac agaagaaagt aaaaatgaag tacttggaag
    10201 aataatagct acaacagata ttaacttagc aaaagatgca gacttggtta tagaggcagc
    10261 tatcgaaaac atgaatataa agaagaaaat atttgctgaa cttgatgacg tatgtaagcc
    10321 agaaacaata cttgcaacca acacctcatc gttatcaata actgatgtag ccagtgcaac
    10381 taaaagacca gataaggtaa taggaatgca cttctttaat cctgtaccag taatgaagtt
    10441 agtagaggta ataacaggaa tggctacttc agcagaaact aaggatacag ttattgaaat
    10501 tacaaaaaaa gttggtaaag atccagtaga ggttaaagaa gcaccaggat ttgtagttaa
    10561 tagaatacta attcctatga taaatgaagc agtgggaatt ttagctgata atgttgcaac
    10621 agcagaagat atagatatag ctatgaagct aggagctaat catccaatgg gaccattagc
    10681 tttagctgac ttgataggaa atgatgtatg cttggctata atggagatac tatatataga
    10741 attcggggat ccaaaataca gacctaatcc tatgttgaga aaaatggtaa gagcaggtta
    10801 cttaggaaga aagactggca agggcttcta tgactattca aaatagtata ataagttttt
    10861 gttattagca ttaatcacta taaatattta attataataa atacttatag tgaaattttt
    10921 aaaaatatag gttgatgggg gagttaaaaa tgaaagaagt agtaatagca agtgcagtta
    10981 gaactgcact aggttctttt ggtggaagct taaaagatat gccagcagtt gaccttgggg
    11041 ctattgtaat aaaggaagca ctaagtagag caggggtaaa tccagagatt gtagacgaag
    11101 taataatggg aaatgtacta caggcaggac ttggtcaaaa tcctgcaaga caatcagcta
    11161 tgaaggcagg tattccttta gaagtatcat catttacaat aaataaagtg tgcggttcag
    11221 gattaagagc cgttagtttg gcttgtcaaa tgatattatc tggttacaat gatatagttg
    11281 tggcaggtgg gatggaaagt atgtcaagag ctccatatgt gttaaatgat gcaagatggg
    11341 ggcaaagaat gaatgatgga aaactcattg atagtatgat taatgatgga cttttggatg
    11401 catttaataa atatcatatg gggattacag cagaaaatat agcagaacaa tggaacataa
    11461 ctagagagat gcaggatgaa tttgctctta gatcacaatt aaatgcagaa gctgctatta
    11521 aagctggaaa atttaaagat gaaatagtgc cagtagccat acctcaaagg aaaggtgatc
    11581 caaagatctt tgatactgat gagtttccaa ggcttggttc aactaaagaa ggcttagaaa
    11641 aattaaaacc ggcatttaaa aaagatggaa ctgttacagc aggtaatgcg tcaggaatca
    11701 atgatggtgc agcagctttt gtaataatga gtgcagaaaa ggcagaggaa ttaggaataa
    11761 agcctttagc taaaatagta tcttttgcat ctaaaggggt agaaccttca attatggggt
    11821 atggtcctgt acctacagtt aaagaagctt taaaaagggc aagtttaaca attgaagata
    11881 ttgatttaat cgaagcaaat gaagcgtttg catcgcaatg tttatcagta gctaaggatt
    11941 tagaatttga tataaataaa gtaaatgtaa atggtggagc tatagcatta ggacatccag
    12001 ttggtgcatc aggagcaaga atattagtta cgcttattca cgaaatgata aaaagagatt
    12061 gtaaaaaagg ccttgcaact ttgtgtatag gcggaggaca aggaacagca gttattatag
    12121 aaagatgcaa ttgatagagg aatgcaagta gatacagatg tagccatatt aatagaagta
    12181 gaagactttg caacagagga tcaaactgaa ggaatggctg catttttaga aagaagagca
    12241 gaaaagaatt tcaaaaataa ataatattat agaattttgc taaaaatcta ttagaggttt
    12301 atatatagtt tgttataaag taggtttaaa taacaaggag ggtaatttaa tgaattttaa
    12361 gttaactaga gaacaagaat tagtacaaca aatggttaga gaattcgcag taaatgaagt
    12421 taaaccaata gctgctgaaa tcgatgagac agaaagattc cctatggaaa atgttgaaat
    12481 aatggctaag ttaggaatga tgggtatccc attttctaaa gaatttggtg gagcaggcgg
    12541 agatgtactt tcatatataa tcgctgtaga agaattatca aaagtttgtg gtactactgg
    12601 agttatactt tcagctcata catcattatg tgcatcagta attaacgaaa atggtactaa
    12661 agaacaaaga gaaaaatatt tacctgatct ttgtagcggt aagaaaattg gtgctttcgg
    12721 attaactgaa ccaggtgctg gtacagatgc tgcaggacaa caaacaactg ctgtattaga
    12781 aggtgaccat tatgtattaa atggttcaaa aatattcata acaaatggtg gagttgctga
    12841 aactttcata atctttgcta tgacagataa atcaaaagga actaaaggaa tttctgcatt
    12901 tatagtagaa aaatcattcc caggcttctc aataggaaaa ttagaaaata agatgggtat
    12961 cagagcatct tcaaccactg aattagttat ggaaaactgt atagttccaa aagaaaacct
    13021 attaagtcaa gaaggtaagg gatttggaat agcaatgaag actcttgatg gaggaagaat
    13081 tggtatagct gcaaaagcgt taggtattgc agaaggagct tttgaagaag ctgttaatta
    13141 catgaaagaa agaaagcaat ttggtaagcc attatcagca ttccaaggat tacaatggta
    13201 tattgcagaa atggatgtta aaattcaagc tgctaaatat ttagtatacc tagcagcaac
    13261 aaagaagcaa gctggtgagc cttactcagt agatgctgca agagctaaat tgtttgctgc
    13321 ggaagttgcg atggaagtta caactaaagc agtacaaatc tttggagggt atggatatac
    13381 taaggaatat ccagtagaaa gaatgatgag agatgctaag atatgcgaaa tctatgaagg
    13441 aacttcagaa gttcaaaaga tggttatcgc tggaagcatt ttaagatagg aggactttta
    13501 taatgaatat agtagtttgt gtaaaacaag ttccagatac cacagcagta aaaatagatc
    13561 ctaaaactgg tacattaata agagatggtg ttccatcaat aatgaaccca gaggataaac
    13621 atgctttaga aggtgcgtta caattaaaag aacaagttgg aggaaaagtt actgtagtta
    13681 gtatgggact tccaatggct aaagcagttt taagagaagc attatgtatg ggagccgatg
    13741 aagctatcct attaacagat agagctatgg gaggagctga tactttagct acttcaaaag
    13801 caatagctgg tgtaatagca aaattagatt atgatttagt atttgctgga agacaagcga
    13861 ttgatggaga tactgcacaa gttggtccag aaatagctga acatttaaat attcctcaag
    13921 taacttatgt tcaagatgtt aaagttgaag agaaatcatt aattgtaagc agagcattag
    13981 aagacggaca tcaagtaatt gaagttaaaa ctccatgttt attaactgca atcgaagaat
    14041 taaatgaaac aagatatatg aatgttgcaa aaatcttcga aacttctgat gatgaaatca
    14101 aagttatgag tgcagctgat atagatgtag atgtagctga attaggactt aaaggttcac
    14161 ctacaaaggt taagaagtca atgactaaag aagttaaggg cgcaggagaa atcgtaagag
    14221 aagcacctaa aaatgcagca tactatgttg taggaaaatt aaaagaaaaa cactacatct
    14281 aagcagacat ccaaaatcta tgatttggtt atggtcgctt actcattcta cgtaggagaa
    14341 ggagtttcat atataaaaaa taggagggta atttattatg aatatagcag attacaaagg
    14401 cgtttgggtc tttgctgaac aaagagaagg ccaattgcaa aaagtatctt tagaactact
    14461 tggtgaaggt agaagaattg ctgatgaatt aggagtaaag ttaacagctt tattacttgg
    14521 aaataatata gagacactcg ctaaaacttt agcagaacat ggtgcagatg aagttttagt
    14581 tgctgatgat aaaaacttag aacattatac aactgaaggt tacactaaag ttatttgtga
    14641 cttagcaact gaaagaaaac ctggaatctt atttgtagga gctactttta ttggaagaga
    14701 tttaggtcca agaatagctg ctagattatc tactggatta actgctgatt gtacatcatt
    14761 agatgtagat gttacaaatg gagatctttt agcaacaaga ccagcctttg gtggtaactt
    14821 aatggctaca attgcatgtc cagaccatag accacaaatg gctacagtaa gaccaggagt
    14881 atttgccaaa attactactg atccatctaa atgtaacatt gaaaaagtta atgttacatt
    14941 agatgattca gatattagaa caaaagtatt agaaacaatt aagtcaaaga aagatatcgt
    15001 tgatatagct gaagctgatt ttatagttgc tggaggtaga ggagttggaa ataaagaaaa
    15061 ctttacacta cttaaagaac tagctgatgc tttaggtgga actgttgctg gatcaagagc
    15121 agctgttgaa aaaggatgga ttgacggagc ataccaagtt ggtcaaactg gtaaaactgt
    15181 taaacctcaa atatatatag cttgtggtat atcaggagct atccaacacg ttgctggcat
    15241 gcaagattca gagcttataa tagctgttaa taaggatgat tcagctccaa taatgaagat
    15301 tgcggattat gcaatagttg gagatcttac taaggtagtt ccagaattaa tagctcaagt
    15361 taaagaaatt aagagtgctg aataattcag tttaattagg gtttgctaag caagccctaa
    15421 tttctgttaa aatttgcttc tttaagttaa atttaattaa gtgatttttc taaaaagttg
    15481 caaaagagat ataaattttt tagaattatg aaacactttt aacttaaatc aataaccaac
    15541 atttcaataa taaagaaggt atattggggg aatacaaatg ctagaaaaat cagttaaaaa
    15601 aagtaccaga ttcgcaatta aagcaaaact tattttagta atgctactat tattaagtat
    15661 acctgtactt atacttggac taatcagtta ttatgttgct aaagctgagc ttgaaaataa
    15721 cggaaagatt ttattaaaaa atagtgttga gatgacatta caagcaatag ataacaatca
    15781 gaaacttgtg gatcagggaa aactaagcct tgaggaagct caagaaaaag ttaaagaata
    15841 tatgcttggt aaaaaacaag ctgatggcac aagaccaatt aataaaaatt taagtttggg
    15901 acaaaacggt tacctactgg catatactca agatggagtt gaagcagttc atccaagttt
    15961 agaaggtaaa aacgtgttag attcaaaaga taaaaaaaat ggcaatttgt ttgttaaaga
    16021 tcagataaaa atagcaaatg atggtggcgg atatttaact tattactgga ctattcctaa
    16081 ttcagatagt attgcagata aaataactta tcaaaagact gatcctcatt ggggttgggt
    16141 aatttgtgct ggaacttaca tgaatgattt taatgttggt tcaaataaaa tttttattac
    16201 tactataatt atattattag tggtgtttat tctaggttca accatcataa tgattttttc
    16261 aaaacacata tccactccaa ttaaagaaat cagtaatgca gtagatgcgg tggccttagg
    16321 taatttaaat attgaaaggt taaaaatcaa aaatagagat gaaatcggta atttgagcga
    16381 ttcatttaat gtaatggtta aaaatgttaa ttcttttata agttcagtta aaaattcagt
    16441 tgatattgtt tttgactctt ctcgattgtt agatgaaata gtttatgaaa atactgcttc
    16501 aattaatgaa gttgcatcat ctgttgaaga aattgccaag ggctcaagtc aacaagctag
    16561 agaaactgag aacggagttc tcagggtaaa aaatttatca gagaaaatag atttagtaac
    16621 cagactaact gtagaaacca acgatattgc aattgaaaca gctgatataa gccataaagg
    16681 cttaaatgca attgaattac tatcaaaaaa atcagatgaa aataatacag ctactgaaaa
    16741 gacaagtgat ataataatgg aagttgataa aaattctgtt gaaattggag ttattactga
    16801 agcaataagt caaatatcag aacaaacaaa cttattatct ttaaatgctg ccatagaagc
    16861 tgctagagct ggtgaacagg gaaaaggttt tgctgtagtt gctgaagaga ttagaaaatt
    16921 ggcttcacaa tcttcaaggt ctgctgaaaa agtcaaagag ttaatcatcg ggatacagga
    16981 taaatcaaag attgctgtaa aaactataga atctggaaag attatagcta aagaacaaag
    17041 caaatcagta ctagaagcca aatatatatt tagcgaaata ttaaaatctg tagaaaaaat
    17101 tacagatgat ctgaaaaact taaaaactta cagccttgaa atggagaatg aaaaagacga
    17161 attaattgat gttttagaaa ctctttcagc ttcaactgaa gaaaattctg cagctactga
    17221 gcaaatttca gctacaagtg aacagcaatt agcaagtatt aatcaagtag ctaaacatac
    17281 tcaagacttg actcaacttg cagaaaaact taaagaagca gttggtgcgt ttcaaattta
    17341 aaacatgtta aatctattaa aataaaacaa gtggacttaa tatgatcggg agatgcattc
    17401 gttggagctg tgttaaagca gttgtctgaa attgaagata agagagattt gagttttgaa
    17461 gaatggaaat aatgaaatga aaaagctata ataacaagat aaataaaaac ttcgcttata
    17521 agtgatccgg taaatgcaaa ataagtgaat actgacttaa ctaaaattga gacccacgac
    17581 gaattgtcgt gggtcatttg attgtagtta gaataccacc tggtgatact gataatatgg
    17641 tttttcacaa catattaaag gaatgattaa agcaaaagtg cattaacaga taaaaacaat
    17701 ctgattatac taagatagaa aatgagtaaa aattttaatt tttaccaata ttaattcttg
    17761 acaaacgaac tggtaaggaa taatattcaa atatacacaa tgtgtaaaaa tactaaatgt
    17821 ataagaaaat acaaagtgta aaaaagaggt gaagagatgg atgtaagaga tatatctact
    17881 gaaagtagaa ttgagagaaa aaaaagggag actagagaga aaattgttaa gatctctatg
    17941 aatttatttc aggatcaagg cttcaataat acaacaatgg agcaaatagc agaaaaaaca
    18001 gatatcgcaa gaaagacact ttataattat ttcccagtaa aagaagctat agttgatgaa
    18061 tatgtaagag gaatttcaca aaaattagct ggagaaaatc ttgaaactat ttggaatctt
    18121 ccaaatacta aatctcgatt agtggcttcg cttaaccata cttatagttg ggttgaaggc
    18181 aacaaggaaa ttatggggat atgtatgaat tatcgcctgc gaaatatgtg taatgattca
    18241 aagactcaaa atgctgagac tggaactcaa agtatcttga accaaattat tagcagagga
    18301 caggaaacag gtgaaattag aaaggatatt tcagttaaac tattggtgac tcatataaat
    18361 attcttcgaa gcgcaatgac ctttgaatgg gtaaatagta catcaaggtt tgagcttcat
    18421 gatgaaatag caaaattggt agatttgttt ctgtatggag cagataaccg attagatagt
    18481 tccaaaaaat ctgagctaga taatataata agtcaggagg aataatagag atgaagtatt
    18541 tttttacctg gaaagaggca tttaaatcag atgcatcact ggtaggaggt aagggatgga
    18601 atctaggacg cttagacaga tatggcttta gtgttccaca aggagtagtt cttattgcta
    18661 aggcttatga tgagtatata aaatacaacc aatttgataa agtaatcagc aatttatctt
    18721 caataattca tctaaataat ttagatgaag gcaatgttaa ggatggactg gatcaattaa
    18781 gaaaaaaaat aatgaatggt tcaatgccgc cagctattgt tgaggaatta tcagggcttc
    18841 taaatagcag tggaaaatta aaaaaatcgt gggcagtaag atcttcagca gttgcagagg
    18901 attctgtaaa ggcttcattt gctggcatac atgattcatt tttgaatgtt tgtggtttag
    18961 aggagattct atcagctgtg aaagagtgtt atgcttcatt gtggtcacct cgggcagttg
    19021 cataccgtag aaacatgaat ataaatgatg atgctgcgac catggcagta gtggttatgg
    19081 aaatggtgga agcgcaggca gctggagtag ggtttacgtg cgatgtccaa acaggacgtc
    19141 aggatgttat gattattaat gccaattttg gattaggtga gtcagttgtg aatggtgcag
    19201 tggagccaga tacatattat ctagaggctg aaacattaaa ctctgaagca aagctaatcc
    19261 aacgaaaaat tggaagcagg caagggatga ctgtgttaaa taaggaaggt ggaactaaac
    19321 ttataccaat tgactcagct gtttcgcagg tgttgtctga ccagaacgtc aaaaagctag
    19381 gtcgtctttt gcagagagta tttgatgctc ttggaaatag tgagcagcat caggatgttg
    19441 agtgggttta taacggtagg gattttgttt tagtccaagc cagacctgtg actattcttc
    19501 caagaaagac ttttcctgct ttacaggaac agaatgatgt ttggtctaat ggcaattacc
    19561 gagattctgt tcctatggtg caatctcctt taaaccgtcg gttaatgaaa aacattattg
    19621 atatcataca tcatacgagt tttacaagct taggttataa actacccgtt ggaatacagt
    19681 tttctaagtt ttataatgga aggctttact gtaacttatc agcttaccag tggggtctgt
    19741 atgcttctat ggggggacga ccagagggat ttaatgattt ttggggaggt catcagccag
    19801 cgattaatat tggtgatcag aaaccagaac ctggatttga agatcgtgca aagaagttca
    19861 gtgagctggt taatgaggct aggaaaaatg ctcctaagat ttgggatgag gtgtcgactt
    19921 caattcaaaa gataactgga agcaggcttg aaacttggaa ggatcaggat tttattgctg
    19981 gttatgatga gttaggacaa attgccggaa tgcttgctaa ggaatttaac tttttagctg
    20041 cggttggtag catgccagtg tttatgctga ttcaaagtct gaacaaatac tttgagggca
    20101 gagagctgat gatgctgaat gcattgatga taggtggaac agatggcatc acaagcgctg
    20161 aacatgggta taggctggtg gaattggctg aaattgcaag aaaagatgta gatgctgcaa
    20221 aatatcttag tgaaatctct tttgatgcat tgggatggag agaactgcct gataattctc
    20281 catttaagaa ggctttttgt gaatttgtca aagaatatgg gcatcgtgca gtatatgaat
    20341 tagatatcat caatcctcgt tggaatgagg agcagaccta tcttctaggt attattcaga
    20401 gtactgtgaa tatagcagat attagtaaat tgagaaaaga gcagaaagag aagcgagaac
    20461 aggtctggaa ggagattaaa gataaagtcc tagattctga gcaaattgct ataagaaatt
    20521 tagtcaagga gtgtcagatt ggggctggag ttcgtgagga gacaaaatca gtattagctg
    20581 aagtcatgga ggcttatcga ataattgcca aaaaattagg tttccgtttt tatgaaagaa
    20641 atctcattaa ggaagaagaa gacatatttt tctgtacttg gtcggaaatt ttttctgtat
    20701 taaatggaga atggaacgga attggacttc aggctctgat tgatatgaga aaaaaatgga
    20761 agaaagaaat ggagttgtta gctccaccag acgtaatttt aggagagaca ccaaggtttg
    20821 aaaaacaggt tagttgtatt tcaagtaatt atctagaagg tgtaccagtt gctgctggga
    20881 aagcctcagg attagctaga ttaatcaaac atccagatga gggagtacga ttacagccag
    20941 aagagattat ggtggtccca tccactgatc cagggtggac gccgctattt ttaaaagcaa
    21001 gggctgttgt tatggaaaca ggaggatttt tatcacatgg agctattgta gcaagggaat
    21061 atggaatccc ggcggtagta aatgtaccag gagtaatgga tattattaag gatggatgga
    21121 caatatccgt agatggaaat aacggtaaaa tattttttga tgataaagac attaaaattt
    21181 gataggggag aattttgata tatgtgccat aattaagtag aatacaaaag aaggagatgc
    21241 tcagttatgc tatggaatca agtaagaaaa acatatccaa ataaatggat tgtatttgat
    21301 agtttaaaac aatatgaaga aaataataaa ttaatcattg aagacgtagc aataatagaa
    21361 gtttatgaag caaaagcata ccttgcatta ttagaagaat caccattaac aggctatgca
    21421 gtagggaaaa attcaggtgt accacgttca aaaatatata aggttttaga tagtcttgct
    21481 atgcgtggag atattttaat tagccatgga agtacacaac agtacgttcc aattccagca
    21541 aaagaactta ttaaaaatcg tcgggtaaaa gctgaagaaa attttaaact tgcagaaaaa
    21601 tctttagaac aatataatca atctgcaaag aatcgtgaga atatctggaa tataactggt
    21661 catgacgaaa tacttgataa agtaaaagaa tgcatcatct cagcaaaaca tagaattctg
    21721 attgaacttt ggaaagagga attcaaagaa ttagaatctg aattaaaaaa ggcatctgat
    21781 aaaggagtag tagtaaccat tatttagaaa atttatagag gtaaaactta ttaagttgaa
    21841 tgatttaaat caattactat gttcggtact aaaagttcta ttacttacta ccgatacggt
    21901 gaacagtatc ataaataaaa taaaacttcc aattattcat agcaaattat acgaagttag
    21961 gcagaaaaaa actcaagcct tgaatttaag cttgagttca aaagttatag aagtccgcct
    22021 aactttggat aattacaata gcacgaaacc gcggaaatat aagcagttat tatggggatt
    22081 gaatagtctc attcccttta attttaaaaa caaattaaaa attaaagttt aaaaatatag
    22141 gggtaaagat ataaaaacgt attaaatagt gcaaaaccgg catagtttcc ccctccccat
    22201 tacaggctat attacgaatg ttatgaagtt ttggtggtta taggaggaga gttacaaaat
    22261 gtaatagacc tattgagttt gtttgagccg cagtgagtgc attttgataa atctctacct
    22321 gtaatttctt taattagttc aagaattgga attttatctc taagtaaaat aggtgtatta
    22381 gtaagttgtt tacaaatatt cagttttgta gttttatttc gattacctag caagccgtag
    22441 tgcctaattt tcataaatcc acttggaagt atatgaataa gaaatcttct aataaattca
    22501 tcagcagaaa tagtcattac cttatactta tttttgtctt tgtaatcacg ccatttaaat
    22561 gtggcattgc cattgtcaat gcttagaata cgggtgtttg atatagcaac tctatgtgta
    22621 tatctaccta aatattcgac gacgcaggca gcatttttaa aaggtggttt acagtaaaca
    22681 atccattctt tagaatatgt agctgaaagt aatttttcga attcaatttc atctgaaaga
    22741 taattttgat tcccatgaaa ttcaagatta ttttcatagt ataattgctt aagataatac
    22801 agaaacttgc ccctaaattt acgagataat actttaaccg gaataaaaaa cttttttctg
    22861 ctgcttatcc atttgccgat cgacgatagt ccgccgccag gtacaatgca gtgaatatgt
    22921 ggatgatgca taagattctg accccaagta tgtagaattg atgtaaaacc aagttttgca
    22981 ccaaggtatt ttttatcaaa ggataattca gataaagttt cagaagtagc cttaaataaa
    23041 atggtataga gttgtctttg attttgatat accatagaat ttagagtatc tggaatagtg
    23101 aatacgacat ggaaatagcc aacgttaagt aaattggatt tttgattgta aatccagcgc
    23161 tcttttgcaa gagcttggca tttggggcag tgcctgttac ggcaggagtt ataagaaatc
    23221 tgagtatttc cacagttatc acaaacatct acatgaccac ctaaatgcga tgttctgcat
    23281 tttcgtattg cagacatagc tttatgttga acaagagtaa gcttatgttt attcaaataa
    23341 tcttcaccat attctataaa tatatcttga acctcaacca ttagttttct ccgtttctgt
    23401 caagaaatct agaggacttt gtacatttaa agattgaatt ttaagtaaat gcaaataaaa
    23461 acatgtagaa ctgatatctg aatgcccaag taattgttta atatgaaata tacttatgcc
    23521 agattctagt agatgtgtag caaaactatg ccttaagcta tggacggtaa cttttttaga
    23581 aatattagct ttttctatgt atttgtggaa tatattttgt acagccttag aagtaatgtg
    23641 tgttccggta tttactcggc tgtaaaaaag ccattctttt ggacgataag ctttccaata
    23701 aactcttaga atttcaaggt tagcttgtga aagcaatgca tagcgatctt tagagccttt
    23761 ggcattgcgg ataaataact gcattttttc actatcaata tcagtaactt ttagagaagc
    23821 aacttcacta agtcttagtc cagcgccata tagagtcatt aatatacatt tatctctaag
    23881 attatcacat gcatcaaaaa ggctttggat ttcactttta gtaagtattt ctggaaattt
    23941 acgttgcctg cggtggcgag gtatttgttt gtaattcaaa gtagcattta aagttacacc
    24001 atataagaat ctaaggccgc tattgtatga atttacactt ccggaagtaa gacctttttc
    24061 tgttgaaaga tagtgcagga attttctaat atctttttcg tcaagttcag tagcgggttt
    24121 gttaaagtgg tcttgaaaaa ttttaacttt agtataatat tcagcttggg tatgtttgct
    24181 tagacctcta agttccacat caaatgtcaa tttttctaag acttgttctt ttgtcataat
    24241 taaaacatct cctttaaatt tagaattatc tatatattaa aggatttata gaaaaaataa
    24301 actggtataa ttaaaatatg agttctagat gtaaatgtat tacatattac caccgcgcta
    24361 gcggtttagt gctattcata caatgggtag ttatataaac agaaaactaa ttaaatgata
    24421 gataaagttt agggcaagta taataagtga atgcgaaagt tattaaaatt ggagaatagt
    24481 gcaggggtta gttacgcttc gcctccacca tgaaacccac gaaaatctaa aatttggatt
    24541 ttcgtgggtc ttttattttg tagatttaaa attattaata gtgaatcgtg ctgtaagtaa
    24601 catagaatat tttaattgat agaaagtagt aaaaaagtaa cacactcact atgaacaaga
    24661 ggagtgtaat aaattaaaaa aactattttt ttcgctaaat atatcacata ataaactcat
    24721 gctaaagttt ataaaatcat cctcattgag tgaaaaatga tctgtgaatg ttttgcctga
    24781 tatagaaaac atatgaaaga atcctgttat taaaaattca gagaatgagt taatttcatt
    24841 gtgtcaaaat ctgttcttat acttccgtct gcctttcctt catcaattat ctttgcaatt
    24901 tcttgagcca attgctcact aactttatta aactcaatac gtttagcaga attttctgct
    24961 gtaggcttaa tatacccaat atagttcatt aagttcaatg tattaggaga gtccttataa
    25021 aattgaaaat aagcatttgt taagtgttta agcttttcaa ttccgttatt tccatttaca
    25081 actgcattct taagcgtaca gaaaagtctt tcaaatcctc taattataac tgagaacagt
    25141 aaatcttctt tatcagtaaa atactgataa atagtttttc tggtaaattg cgattcctta
    25201 gctatcgctt ccattgaggc tccattatag ccaatcatag taaagacttt ttcggcagca
    25261 tttatgatat ctttttctct tactaatttt tctttttctt ttctagaaat tgtacacata
    25321 aaatatttgc aggtatttta tatgagactt cttaggtagt acacctctaa gttttggata
    25381 aaatt
//
