LOCUS       NZ_KB907787.1          15744 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KB907787.1 Dyadobacter beijingensis DSM 21582
            H144DRAFT_scaffold00002.2, whole genome shotgun sequence.
ACCESSION   NZ_KB907787
VERSION     NZ_KB907787.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:27:05
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15744
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15744
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2209:5744]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2210..5744
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15744
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15744
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(3..1886)
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="MIFVMALSFSSAFATHFRAGEITARRLALNTPTYELKLTGYFDMA
                     TGKEAADRQTSVVFIINNAEGTGTPVRIEAPRIPPIVDIGNSTTQNVYIATYTFTSVGA
                     YRISVEEDARNQSVLNIGPKPTSSLNFFVNTVLEINAAFGLNRTPVLRNAPIDVAAVGQ
                     RYIHNPAAFDADGDSLAYRMFVPQRIGPNGTGLNLEYQDPNRVTPPGQTETGASPATFG
                     LNPVTGDLTWDAPMTKGYYNVAFVVEEWRDGVLIGQIVRDMQIIVEDAKNDRPVIPPLP
                     DLCVEAGTLINQTVVATDKNGNKLTLTSASGVYDATLIKPELARFTVANQGAQSRVTGT
                     FTWQTSCDHIRPEPYNVLFKVEDGPPPGYPNPSLFQKLADMTTLNIRVYAPRATGLRGL
                     AAADPAGVAYRLTWDPYKCQIPGAKIVIYRAEKCTDLPDPVCTTGIPAGSGYEQIGRVD
                     VNQTTFLDNNAGEGLRAGVSYSYRLVVIFPRPGANPSDPGYLTGGAESLVSAEFCLNLP
                     MVMPVITNVTVDSTSTTRGVITFKWTRPAASAGSPAQYRLYRAIGQNGPTFTQVATINA
                     SLTPGTVDTIFVDRALNTEANAYNYKLEYWTTQNGQLTKFDETETASSVRLE"
     CDS             2210..2881
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_2"
                     /sec_met_domain="SucD_FumR (E-value: 6.6e-19, bitscore:
                     64.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWFSQTLTSSIGKKLLMALTGLFLISFLVIHATINAMIFYNDGG
                     ETFSHWGHFMGTNPIIRTLEIGLVAGFLIHIIDGLMLWKSNRDARPVKYAVNNAAANST
                     WYSRSMGLLGTLLLIFLVIHTSHFWIPNRSNQFATGEELNLYQMMLDIFQNPIVVLIYV
                     LGCVSLFWHLLHGFKSAFQSLGLNHVKYNGAISFVGTAFSIIVPILFALMPISIYLGWV
                     K"
     CDS             2928..4916
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 177.4; E-value:
                     1.7e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.4e-53, bitscore:
                     177.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 6.5e-40,
                     bitscore: 132.4, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATSSRLDAKIPQGPLETKWSKYRSSVPLVNPANKRNLEVIVVGT
                     GLAGASAAATLAELGYKVKAFCFQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDT
                     IKGGDYRAREANVHRLAEVSGNIIDQCVAAGVPFAREYGGLLSNRSFGGTQVQRTFYAA
                     GQTGQQLLLGAYSGLQRQVGMGTVKMYNRHEMLDVVNIDGKCRGIIARNLITGEIERHG
                     GHAVLLCTGGYGNVFYLSTNAMGSNVTAAWKAHKRGAFFGNPCFTQIHPTCIPVSGEHQ
                     SKLTLMSESLRNDGRIWVPKKKDDNRPGNEIPEDERDYYLERRYPAFGNLVPRDIASRA
                     AKERCDAGYGVGTSKLAVYLDFAAAVERYGRGEANKNNIHNASDADIITWGKAVVKEKY
                     GNLFDMYKQITGEDPYEVPMRIYPAVHYTMGGLWVDYNLMTTVPGLYSLGEANFSDHGA
                     NRLGASALMQGLADGYFVIPYTIGNYLASEIRTGKISTDHEAFVKAEAEVKERIDTLLR
                     IQGKTSPELFHRRLGKIMWDKCGMARNAEGLKQAIEEIRQLRRDFWSDVKVMGTASYFN
                     PELDKANRVADFIELGELMCIDALDRNESCGGHFREEYQTEEGEALRDDENYMYVSAWE
                     HKGPENWELHKEELVYENIKIAQRSYK"
     CDS             4992..5744
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_4"
                     /sec_met_domain="Fer2_3 (E-value: 2.5e-25, bitscore: 84.9,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.6e-11, bitscore: 39.7,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.7e-05, bitscore: 19.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLSLKVWRQSDKDAAGGFEDYKLDHVSPDMSFLEMFDVLNEQLI
                     EEGKEPVAFDHDCREGICGMCSMYINGRPHGPLRGVTTCQLHMRSFKDGDTIVVEPWRA
                     QAFPVIKDLVVDRDAFDRVISAGGFVSVNTGNAQDANALPIAKEAADDAFAAAACIGCG
                     ACVAACKNASAMLFVSAKISQLALLPQGQAERSIRAEKMVAQMDAEGFGACTNTGACSA
                     ECPKEISLENIARMNREYIGAKFSSSAV"
     CDS             complement(5880..6506)
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="VNNNTSLIWNVVLSLAVAVLFFLHFSSKSSSDSGAAADGAVVAGR
                     RTVYVQVDSLLKNYDFFKDTRKELENKNFQLENELTTKGRSLQNEVAFFQQRAQTMTPE
                     QARSTEAQLMKKQQDLMAYRDQSAQALGQEEAKKNEELYKNIRSYIDKYNKENGYEYVL
                     GYSLGGGILFANPSLDVTQKIIDGLNKEYKNSGKAAAPADTTKKK"
     CDS             complement(6604..6969)
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MNFLIVAILSAILQIFTPWWVIAIVPFVILLWRPATSPGAFWTGF
                     GGIAVPWLIYGYYQHFISDGALSDRVAKIFMLPSGLLLLLVTAMISGLVGGFSGLSGYW
                     VRQIFRRNPIPLSARTS"
     CDS             complement(6981..9434)
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MKFLKAILCIAITAGLVYVLDKPWGPAPAMGPFLSPYCGLWQNSE
                     QVIDPKTRVTLQLDSLREEITIRFDDYGVPHIFAKNDFDLFYAQGYITAKDRLWQMDLQ
                     TRAAAGRLSEILGPATLAMDQQSRRLGMGYGAEANLKFAMTDPKTREALLGYTAGVNAF
                     IRQLAPKDYPIEFKLLGYKPEPWKPINTMYMLEQMTLTLAGRSNELAMTNALKKYGRET
                     IAKLFPDYPMLQESPIIPSGTAWDFPKLPIPRVIPPMIPGDSNALSRRSALSLPERTPK
                     EEGIGSNNWAVGAEKSVTGYPILANDPHLELSLPSIWYQVQLHSPDMNVYGVSLPGVPS
                     VIIGFNQQVAWGVTNVDADVFDLYKIKFKNEYRNFYWHDDQWKPTHKREEVIHIKGQKP
                     YHEQVIYTHHGPVTDTDGSFGDLPNLAIKWIGHEPGNSFMTFYELNKSRNFADYRKALT
                     HYVGPAQNFVFADNEKNIALTVNGKLPLKYKEQGKFLLDGSTSADDWHGWIPAEQNPFV
                     KNPPRGFVSSANQSSADTTYPYYINWSFAPSERGIRINERLQAMTNANADSLRMLQNDN
                     FSVLGRTLLPKLLGILEKRPLTPKQKAARILLSNWNYQNTPESVAASIFETWFPLLGQA
                     IWNDDFASPEAPMEYPSRDRTLYLILKQPNEKWFDNVNTPEKETLPDLAYTTFNAALDT
                     LTARKGAMSPEWQWSKVKAAEIRHLSRSIKPFNAPPLVTGGGSSIVNAMTKRKGPSWRM
                     VVELGPTPRAYGIYPGGQSGNPGSPYYLNLLKKWEKGELNELIFLSSPDQKVPHMASSL
                     VLQKR"
     CDS             complement(9471..10202)
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MTIEICAYSLESCINAQAGGAGRIELCGGLGEGGTTPSAGLIEIV
                     RKHVDIPVYVMIRPRGGDFVYDFFEEEIMRKDIDLAKKLGANGVVLGILTPEGQVDVAR
                     TKALVDYAAPLKVTFHRAFDLTPDPMKALADVIATGAERILTSGQKPSAIQATDLLARL
                     SQAANSKIEIMAGGGVNHQNAAELKAAGVHSLHLTAKKFRPARQKFFPDGISMAGEIPD
                     EKSVMYADLELIEAMVQAVSE"
     CDS             10738..10959
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MYWTLELASYLEDAPWPATKDELIDFAIRTGAPLEVVENLQELED
                     DGQPYESIEEIWPDYPTKDDFFFNEDEY"
     CDS             11149..11802
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MELRLLKELVKKGEGEHLEFKLKSNHPEKIVREVVAFANSGGGKL
                     LVGVGDDKTIKGLKDAEEDEFALTRAIDKYIYPKISFKRERVAITPDRDVLVLTIPRSI
                     DKPHYVVDDTGARQAYIRVEDKSIQASREMKEIMRRGRGEHDIRFQYGEKEEKLMKLLD
                     EKESVTVDLFATVAGIPRKIASNTLVVMVLARILEVHPHEMIDKFTMSMAYQSN"
     CDS             complement(11809..12192)
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MNNLIIVFVGGGLGSLARYGIGKVFSQWPSVFPFGTLTANILACL
                     ILGVFGGWATFKSTDLVAASRLFVVVGFCGGFSTFSSFSNETIQLFLHDHWFEAGTNIL
                     VSIIACFAATFLGIWLGKTFLAI"
     CDS             complement(12220..12579)
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="MEVSGTVIALLPEVTGQGKNGMWRKQEFILEIPSQYPKKVCISLW
                     GDKIDQANLQVNDSVTASIDVESREYNSRWYTEVRAWKVEKAGASGGNAGHNAGGAPLP
                     PVTTFTEDESDDLPF"
     CDS             complement(12659..13804)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cys_Met_Meta_PP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_13"
                     /sec_met_domain="Cys_Met_Meta_PP (E-value: 1.2e-154,
                     bitscore: 510.7, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFATKAIHAGIEPDPGTGAIMTPIYQTSTYVQESPGKHKGYEYA
                     RSSNPTRTALQTALAALENGKHGLAYASGLAATDAVLKLFHPGDEIIAPSDIYGGTYRL
                     MKRIFEPLGLVFRFIDIDETDNIAQLITDKTRLVWLETPTNPLLKIIDIESITCVCRER
                     NVLTCVDNTFASPYLQNPLDLGADIVMHSVTKYLGGHSDTVMGALVTSDDDLAGRLKFI
                     QNASGAVPGPQDCFLVLRGIKTLHIRMQRHCENAVQVATWLNAHPKVGKVYYPGLPDHP
                     GHALAAKQMRGFGGVVSFELQDDSYEKAVRTMENLQIFALGESLGGVESLCTHPASMSH
                     GGMPREERLKIGLKDTLIRLSVGIEDVADLIADLDQAIGTD"
     CDS             13959..14591
                     /locus_tag="ctg2_14"
                     /transl_table=11
                     /translation="MTIVPLVTTSILTAWAINQEKVLRELPIEWWLGVTFILTLASASA
                     LTPPTFLALVYGYFLGWASVPMLFALNIGAIAIIYVSAHFLHAASVRNYLIQVYPQVGT
                     LLRRFYKNELRLIFFAKLSPVLPFAITNLFFAMAGARFKQVLTGGTLGMIPRTLLAVWA
                     GKEAQDIRYLLEHPNEGLATKIVLIALIVVSTVGIGYFFKDKSMVES"
ORIGIN
        1 tgttcgagcc tgacggagct ggcggtttcg gtttcgtcga acttggtcag ctggccgttt
       61 tgagtggtcc agtattcgag tttatagttg taagcgttgg cctcggtgtt caatgcgcgg
      121 tctacgaaga tggtgtcgac cgttcctggc gtaaggctgg cgttgatggt ggctacctgg
      181 gtaaatgtcg ggccgttctg gccgattgcg cggtagaggc ggtactgtgc aggcgatccg
      241 gcagaagcgg caggccgggt ccatttaaag gtgatgacac cgcgggtagt gctggtcgag
      301 tctaccgtca cgttggtgat gaccggcatt accatcggca ggttcagaca gaactccgcc
      361 gaaaccaggc tttctgcacc gcctgtcagg taaccggggt ccgacgggtt ggcgccgggc
      421 ctcgggaaga tcaccaccag ccggtaagag taggaaacgc ctgcacggag gccctcgccg
      481 gcattgttat ccaaaaatgt agtctggttg acatccaccc ggccgatctg ctcgtaaccc
      541 gagccggccg gaatgcccgt cgtgcaaacc ggatcgggca ggtcggtgca tttttcggcg
      601 cggtaaatga cgattttggc tccggggatc tggcatttgt aagggtccca cgtaagccgg
      661 tacgcaacgc ccgccgggtc ggcagccgct aagccccgca gcccggtcgc cctgggggcg
      721 tatacccgga tgttcagcgt cgtcatatcg gccagtttct ggaacagcga cgggttagga
      781 tagcccggtg gcgggccgtc ttctaccttg aaaagcacat tgtagggctc gggccggatg
      841 tggtcgcagg aagtttgcca tgtgaatgtg cccgtaacgc ggctttgcgc accctggttt
      901 gctacggtga accgcgctaa ttcgggtttg atcagtgtcg cgtcgtatac gccgctcgcg
      961 gaggtcagcg tcagtttgtt gccgtttttg tccgtcgcga ccactgtctg gttgatcagc
     1021 gtgccggctt ctacgcagag atcgggcagg ggtgggatta ccggccggtc gtttttggca
     1081 tcttcgacga tgatctgcat atcgcggact atctgcccga tgagcacgcc gtcgcgccat
     1141 tcttccacga cgaacgcgac attataatag cccttcgtca tcggcgcgtc ccaggtgagg
     1201 tcaccggtga cggggttcag tccgaatgtg gcaggcgaag cgcccgtttc ggtttggccg
     1261 ggcggcgtta ccctgttcgg gtcctggtat tcgaggttga ggccggtacc attcggcccg
     1321 atccgctgcg gtacaaacat gcggtaggcc agactgtcac catccgcgtc gaatgcggcc
     1381 gggttgtgaa tgtaccgctg gcccaccgcc gcgacgtcga tcggcgcatt ccgcagcacc
     1441 ggcgtgcggt tcagcccgaa tgccgcattg atttccagca cggtattgac gaaaaagttc
     1501 aggctgctgg taggtttcgg gccgatattc agcacgcttt gattgcgcgc gtcctcttcc
     1561 acggaaatgc ggtatgcgcc cacggaagtg aaggtgtagg tggcgatgta cacattttgc
     1621 gttgtgctgt tgcctatatc cacgatgggc gggatgcgcg gcgcttctat ccgcacgggc
     1681 gtacccgtcc cttcggcatt gttgatgatg aaaacgacgg atgtctgccg gtccgccgcc
     1741 tcttttcccg tggccatatc gaaatagccg gtcagtttga gttcgtaggt aggggtgttg
     1801 agcgcaagcc ggcgggcggt gatttccccg gccctgaaat gggttgcgaa tgcgctgctg
     1861 aatgacaatg ccatcacgaa gatcatgatc aggctccggg aagatagagg tatacgcatg
     1921 ggtaggttcg ttggtcatcc agttatgtaa caattcaacg aaactcctgt aagaaaatgt
     1981 gtccttaacg gttacaaaat aagttgaggt cgacagctga gcccttcgcc ctgagcgtct
     2041 tgcttttatt aagcctaatc agtctaaata tttcttcata atgattataa ataaacaggg
     2101 cggctggcaa aaatgaaagc gtttttttgt ctcgcatagg tttgtgatat acctttgaaa
     2161 ggttctaaat atacctcaat tttttgcact aaaaccattc gtttttgtta tgtcgtggtt
     2221 ttcacaaacg ttaacgagct ctatcgggaa aaaacttttg atggctctta ccggactatt
     2281 tttgattagc tttctggtga ttcatgccac catcaatgcc atgatttttt acaatgatgg
     2341 cggagagaca ttttcccatt gggggcactt catgggtacc aacccgatta tacgtacgct
     2401 tgaaatcggc ctcgtagcgg gctttctgat ccatattatc gatggtttga tgctctggaa
     2461 aagtaaccgc gatgcccgtc cggtgaaata cgccgtcaac aacgccgctg caaacagcac
     2521 ctggtactcc cgtagcatgg gtttgctcgg aacattgctt ttgatcttcc tggtgatcca
     2581 cacgtcgcat ttctggattc ccaaccgttc caaccagttc gcgacaggcg aggaattgaa
     2641 cctgtatcaa atgatgctcg atatcttcca gaacccgatc gtcgtgctga tttacgtgct
     2701 cggctgtgtg tcgctcttct ggcatttgct gcacggcttc aaaagcgcat tccagtcgct
     2761 ggggcttaac cacgtgaagt acaacggagc gatttcattt gtaggaactg cattctcgat
     2821 tatcgtgccg atcctcttcg cgctgatgcc gatttcgatt tatctgggct gggtgaagta
     2881 atcccggcaa gtttcatttt caaatttctg attaaataat atttgatatg gcaacgtcat
     2941 ctcgtctgga tgccaaaata ccacaaggac cgcttgaaac taaatggagc aaataccgct
     3001 cctcagtacc acttgtaaac cctgccaaca aacgtaacct ggaagtgatc gtcgttggaa
     3061 ccggcctcgc gggtgcttcg gcagctgcta cactggccga gctcggttac aaagtgaaag
     3121 cgttctgttt tcaggattct ccccgccgcg cacactccat cgccgcgcag ggagggatca
     3181 atgccgcaaa gaactaccag aacgacggtg actcggttta ccgtcttttt tatgatacca
     3241 ttaaaggagg tgactaccgc gcgcgtgaag cgaacgtaca ccgcctggcc gaagtttcgg
     3301 gtaacattat cgaccaatgc gtagccgcag gcgtgccttt cgcgcgcgag tacggcggac
     3361 tgctgtccaa ccgctcgttc ggtgggacgc aggtgcagcg taccttctac gcagccggcc
     3421 agacgggcca gcagctcctg ctcggggcct attcaggctt gcagcgccag gtagggatgg
     3481 gtaccgttaa aatgtacaac cgccacgaga tgctcgacgt cgtgaatatc gatggcaaat
     3541 gccgcggtat catcgcacgt aacctcatta ccggcgagat cgaaagacac ggaggtcacg
     3601 cggtactgct ttgtacaggt ggttacggaa acgtgttcta cctttcgacc aatgcgatgg
     3661 gcagcaacgt taccgccgca tggaaagccc acaaacgcgg tgcattcttc ggtaaccctt
     3721 gttttaccca aattcacccg acttgtatcc ccgtatcagg cgagcaccag tcgaaactca
     3781 ccctgatgtc ggaatcgttg cgtaacgacg gccgtatctg ggttcccaag aaaaaagacg
     3841 acaaccgccc gggtaacgaa atccccgaag acgagcgcga ttactacctc gaacgccgtt
     3901 accctgcctt cggtaacctc gtaccgcgtg acatcgcgtc gcgtgcggcg aaagagcgtt
     3961 gcgatgccgg ttacggtgtc ggaacttcca aactggcagt ttacctcgat ttcgctgcgg
     4021 cggtagagcg ttacggacgc ggcgaagcca acaagaacaa tatccacaat gcatccgatg
     4081 ccgacattat tacatggggt aaggcagttg tgaaagaaaa atatggtaac cttttcgata
     4141 tgtataagca gatcacgggt gaggacccgt acgaagtgcc tatgcgtatc tatcctgcgg
     4201 tgcactacac catgggcggt ctttgggtgg attataacct gatgaccacc gtaccgggct
     4261 tgtactcgct gggcgaagcc aacttctccg accacggcgc caaccgcctc ggtgcttcgg
     4321 cgctgatgca gggcctggcc gacggttatt ttgtaattcc ctacacgatt ggtaactacc
     4381 tcgcgagcga aatccgcacc ggaaaaatct cgacagacca cgaagcattc gtgaaagcgg
     4441 aagcggaagt aaaagagcgc atcgacacat tacttcgcat tcagggcaaa acctctcctg
     4501 agcttttcca ccgccgtctg ggcaagatca tgtgggacaa atgcggtatg gcgcgtaatg
     4561 cggagggctt gaaacaggca atcgaagaga tccgtcagct gagaagagat ttctggtcgg
     4621 acgtgaaggt aatgggtacg gcatcgtact tcaaccccga actcgacaag gcgaaccgcg
     4681 tggccgactt catcgaactc ggcgagctga tgtgtatcga tgcactcgac cgtaacgaat
     4741 cctgcggcgg ccacttccgc gaagagtacc agacggaaga gggcgaagca ctgcgcgacg
     4801 acgaaaatta catgtacgta tcggcctggg aacacaaagg cccggaaaac tgggagcttc
     4861 acaaggaaga gctcgtatac gaaaacatta agatcgcgca acgcagctat aaataaaacc
     4921 tccggtggca cggatttatg ccacgcttaa aagttgtatc agaaataaag aatataggta
     4981 tggaaggaaa tatgaggttg tctctgaaag tttggagaca aagcgataaa gacgccgcgg
     5041 gaggtttcga ggactacaag ctggaccacg tttcccccga catgtcattt cttgaaatgt
     5101 tcgatgtact caatgagcag ctcatcgaag aaggaaaaga gccggttgca ttcgatcacg
     5161 actgccgcga aggtatttgc gggatgtgtt cgatgtatat caatggccgt ccgcacggac
     5221 cgttgcgcgg ggtaactacc tgccagctgc atatgcgctc gttcaaagac ggcgatacca
     5281 tcgtggtaga gccctggaga gcacaggcat ttccggtgat taaagacctc gttgtagacc
     5341 gcgacgcatt cgaccgcgtg atctccgcag gtggtttcgt atctgtaaat accggtaacg
     5401 cacaggatgc caatgcattg cccatcgcca aagaagcagc cgacgacgca tttgcggcag
     5461 cggcatgtat cggatgcggc gcttgcgtag cagcttgtaa aaatgcttct gcgatgcttt
     5521 tcgtatcagc caaaatctcc cagctggcat tgttgccaca gggacaggca gaacgcagca
     5581 tccgcgccga gaaaatggtc gctcaaatgg acgcagaagg cttcggcgcc tgcaccaaca
     5641 ccggtgcctg ctcggcagaa tgccctaagg aaatcagcct cgaaaacatc gcccgcatga
     5701 accgcgaata catcggcgcg aagttctcgt cttcggcggt ttaaggatat attaaatgcc
     5761 aatgcagggc agccggtttt ccggctgccc tgtttttgtt ttttgcgcgg gtatagaaaa
     5821 ataatagcag atgatcgtgc gaccatctgc tattgtctta aatggatatt tcagaaatac
     5881 tacttcttct tggtagtatc agccggtgcg gctgctttgc ctgagttttt atattctttg
     5941 ttcaggccgt cgatgatctt ttgcgtaaca tccaaagatg ggtttgcgaa gaggataccg
     6001 ccgcccagcg agtagccgag tacatattcg taaccgtttt ccttgttgta tttatcgatg
     6061 taagagcgga tgtttttgta gagctcttcg ttctttttag cctcttcctg gccgagcgcc
     6121 tgagccgact gatcgcggta ggccatcagg tcctgctgct ttttcatgag ctgcgcctcg
     6181 gttgagcggg cttgctcagg ggtcatcgtc tgagcgcgtt gctggaaaaa tgccacttca
     6241 ttttggagcg agcgtccttt ggtagttaac tcgttttcaa gctggaaatt cttgttttca
     6301 agctcttttc ttgtgtcttt gaagaaatcg tagtttttca aaagcgaatc cacctgaacg
     6361 taaacagtac ggcggcctgc cactactgcg ccatctgcgg ctgcacctga atctgacgac
     6421 gatttgcttg aaaaatgaag gaagaataac accgccaccg caagcgaaag gacgacgttc
     6481 cagatcaatg aagtattatt gttcacgttt ttaaggttta ttgttttttt gaacgagccg
     6541 caaagataat gatttgtgtt taagtacaat gaataagtgg ggcctgagcg ccggtcgcat
     6601 gcatcatgac gtgcgggcgg acagcggtat agggttcctg cgaaagattt gccgcaccca
     6661 atagcccgaa agccccgaaa aaccgccaac aagcccgctt atcatggctg ttaccagcag
     6721 cagcaacagg ccgctgggca gcatgaaaat cttcgcgacg cggtcggata atgcgccgtc
     6781 ggaaatgaag tgctggtagt agccataaat cagccagggt acggcaatgc cgccgaagcc
     6841 cgtccagaaa gcgcccgggg aggtggccgg ccgccataga aggatcacga acggcacgat
     6901 ggcgatcacc caccagggcg tgaaaatttg cagtatggcc gacaggatcg cgacgatgag
     6961 gaagttcata aaaatcgtgg ttaacgtttt tgtaatacaa ggctcgacgc catatgcggc
     7021 accttctggt cgggcgatga caggaatatc agctcattga gctcgccttt ctcccacttt
     7081 ttgagcagat tgaggtagta agggctcccc ggattgcccg attgcccgcc aggataaatg
     7141 ccgtaagccc gcggcgtcgg cccgagctcc accaccatcc gccaagaagg gcctttgcgt
     7201 ttggtcatcg cattgacgat gctgctccct ccgccggtca ccagcggcgg tgcattgaat
     7261 ggcttgatgc tcctgctcaa atgccgtatt tccgccgcct ttaccttcga ccattgccat
     7321 tccgggctca tggcgccttt gcgggcagtg agcgtgtcga gggccgcatt gaaagtggta
     7381 taagcgaggt ccggcagcgt ttctttttca ggtgtattca cattgtcgaa ccacttttcg
     7441 ttgggttgct tcaatatcag gtataatgtc cggtcgcggg acggatactc catcggcgct
     7501 tccggcgagg cgaagtcgtc gttccagata gcctggccga gcagcggaaa ccaggtttcg
     7561 aatatggaag cagccaccga ttcgggggta ttctggtaat tccagttcga aagaagaatg
     7621 cgtgcggctt tttgcttcgg agtaaggggc cttttttcca gaatgcccag caatttgggc
     7681 agtagcgtcc gtccgagcac gctgaaatta tcgttttgca gcatacgcag gctgtcggcg
     7741 ttggcattgg tcatcgcttg cagccgttcg ttaatgcgaa tgccgcgttc ggaaggcgcg
     7801 aaactccaat tgatataata aggataagtt gtatcggccg acgactggtt ggcgctgctc
     7861 acaaagcctc tcggcgggtt tttgacaaac ggattctgct ccgcgggaat ccagccatgc
     7921 caatcgtccg cggatgtaga gccgtcgagc aggaacttcc cttgttcttt atatttcaat
     7981 ggaagcttgc cgttgacggt cagggcgatg ttcttttcat tatccgcaaa gacaaaattc
     8041 tgagccggtc ccacgtaatg cgtcagcgct ttacggtaat cggcgaagtt tcgggatttg
     8101 ttcagctcat agaacgtcat gaaactgttg cccggctcat gcccgatcca tttgatcgcc
     8161 aggttaggca aatcaccgaa cgagccgtcc gtatccgtta ccgggccgtg gtgcgtgtaa
     8221 ataacctgtt catgataagg cttttgccct tttatgtgaa tcacctcttc gcgtttgtgg
     8281 gtcggcttcc attggtcgtc gtgccagtag aaattgcggt attcgttttt gaatttgatt
     8341 ttgtataaat caaaaacatc ggcgtccacg ttggtaacgc cccaggctac ctgctggttg
     8401 aaaccgatga tcacgctcgg cacgccgggc agcgacacgc cgtatacatt catatccggc
     8461 gaatgcagct ggacctggta ccagatcgac ggcagcgaca attccaggtg ggggtcgttg
     8521 gcgaggatag ggtagccggt caccgacttt tcggcgccca ccgcccaatt gttactgcca
     8581 atgccttcct ctttgggcgt ccgttcgggc agcgatagtg ccgaccgccg ggacaatgca
     8641 ttgctatcgc cggggatcat cggcggaata acacgtggaa tgggcagttt cgggaaatcc
     8701 caggctgtac cggaggggat aatcgggctt tcctgcaaca tcgggtagtc ggggaagagc
     8761 tttgcgatcg tttcgcggcc gtattttttc aatgcattgg tcatagccag ctcgttggac
     8821 cgtcccgcta gcgtgagcgt catctgttcg agcatgtaca tggtgttgat cggcttccag
     8881 ggctcaggct tgtagcccag cagcttgaat tcgatcgggt aatccttcgg cgcgagctgg
     8941 cggatgaatg cattcacgcc cgccgtgtag cccagcaacg cttcccgcgt cttcggatcg
     9001 gtcatcgcga atttcaagtt ggcttcggcg ccgtagccca tgcccagccg acggctctgc
     9061 tggtccatcg ccaatgtggc cgggccgagg atctcggaaa gcctgccagc cgcggcgcgg
     9121 gtttgcaggt ccatttgcca gaggcggtct ttggccgtaa tgtagccctg cgcgtaaaaa
     9181 aggtcgaagt cgtttttggc aaaaatatgc ggcacgccat agtcgtcgaa gcgaatggtg
     9241 atttcctcgc gcaggctgtc gagctgtaag gtaacccgcg ttttcgggtc gatcacctgc
     9301 tcgctgttct gccacaggcc gcaatatggg ctcaggaacg gccccatcgc gggcgcaggc
     9361 ccccagggct tgtccagcac gtagacgagc cctgcggtaa tggcgatgca caaaattgcc
     9421 tttaagaact tcatagagag gatgttgatg gatgcgttat aaatggcggg ctattcggaa
     9481 acggcctgaa ccatggcttc gatcagttcg agatcagcat acatgactga tttttcgtcg
     9541 ggaatctcgc cggccattga aatgccgtcg gggaaaaact tctggcgtgc ggggcggaac
     9601 ttcttggcgg tcaagtgcaa tgaatgcacg cccgccgctt ttaactcggc ggcgttctgg
     9661 tggttgacgc ccccgccggc catgatctcg attttactgt tggccgcctg cgaaagtctg
     9721 gccagcaaat ccgtagcctg aatagccgaa ggtttctgac cggacgtcag gatacgctcc
     9781 gcgccggtag cgatcacatc ggccagcgct ttcatgggat cgggcgtgag gtcgaacgcg
     9841 cggtggaatg tcactttcaa cggggccgcg taatccacca atgctttggt acgagctaca
     9901 tccacctggc cttcgggcgt gaggatgccc aggacgacgc cgttggcgcc cagttttttg
     9961 gccagatcaa tgtctttccg catgatttct tcttcaaaaa aatcatacac aaaatcaccg
    10021 ccccgtggcc ggatcatcac ataaacgggt atatcgacgt gttttctaac gatttcaatc
    10081 agtcccgcgc tgggggtggt accaccttcc ccgaggccgc cgcatagttc aatcctgccc
    10141 gccccgccgg cttgtgcatt gatacacgat tccagcgaat aagcgcaaat ttcaatagtc
    10201 ataatctggt atttgtaatg aagagggaaa ttaagggttt ttcggggaga ggggaaatgt
    10261 cgcggttaca aactttgtaa ttcaaaagaa aattaccaat cttccgaagc cggcacacac
    10321 aagcagtatg atcggattac cgatatcagg catatgtgaa tggtctgaaa acgccggaac
    10381 gaatcaggag tgagctgcgg ccaatacgct cggaggccac ttaccgggag tatttaggaa
    10441 ttatcgacgg gctagtggat tgtgcagagg aatactaaag aggaggagct tctggaactg
    10501 gtttctatct tagtcgaaaa ctatgaagcg cagcataagg ggttaggagt ttctgtggaa
    10561 actttattgg cggtttgagt tttaattatt tgattttcaa ttaattaaat taaaaaagaa
    10621 aatatatttt gtaacctgac aattattttt cttttttttc gctttaagct tttaaaagat
    10681 agcaaatttt ttacttttgc agaaaagtga agtaaccatt taataggcga aaatattatg
    10741 tactggactc tcgaactcgc atcgtacctt gaagatgctc cctggccagc taccaaagac
    10801 gagctaattg actttgcaat cagaacaggc gctccgttag aagtagttga aaaccttcag
    10861 gagcttgaag atgatggtca gccttatgaa agcattgagg agatttggcc cgactatccc
    10921 accaaagacg atttcttttt caatgaagat gaatattaaa tgaaaacggc actctatcgg
    10981 tgccgttttt tttgtgataa atggtccgct tttttcacgt aactcgatcc ccataatttt
    11041 ttaaatctga caaaaggaat gtaaattgtt agcgttaact aatgaggagg acgaggtaag
    11101 ttaccgaaag tgatttgtca taactcacaa tttatccatt ccaacccgat ggagcttcga
    11161 ttgttgaaag agctggttaa gaaaggtgaa ggggagcatc tggaattcaa actgaaatcc
    11221 aaccatcccg agaaaatcgt ccgcgaagtg gttgccttcg caaattcagg cggcggcaag
    11281 ctgctcgtcg gggtaggtga cgataagacg atcaaaggcc tcaaagatgc ggaggaggac
    11341 gaatttgccc tcacgcgtgc catcgacaag tacatttatc ccaaaatcag cttcaaacgt
    11401 gagcgcgtag ccatcacgcc cgaccgtgac gtgctcgtgc tgacgatccc gcggagcatc
    11461 gacaagccgc attatgtggt ggacgatacc ggcgcgcgcc aggcgtacat ccgcgtggaa
    11521 gacaaatcca tccaggccag ccgcgaaatg aaggaaatta tgcgacgcgg ccgcggtgag
    11581 cacgatatca ggtttcaata tggtgaaaag gaagaaaagc tgatgaagct cctcgacgaa
    11641 aaggagtcgg tgacggtgga tttattcgcc acggtggccg gtattccccg caaaattgct
    11701 tccaatacat tggtagtgat ggtactggcc cggatactcg aagtgcatcc gcacgagatg
    11761 atcgacaagt ttacgatgtc gatggcttat cagtcgaatt gacctgagtt atattgccag
    11821 aaaggttttt cccagccata ttcccaaaaa tgtagctgcg aagcatgcta tgatgcttac
    11881 cagaatgttg gtaccggctt cgaaccagtg atcgtgtagg aaaagctgga tggtttcatt
    11941 gctgaaactt gaaaacgtac tgaacccgcc gcagaagccg accactacaa aaagtcgtga
    12001 ggcggcgacg aggtctgtgg atttgaatgt ggcccatccg ccgaacacgc caagtatcag
    12061 acaggccaaa atattggccg tcaatgtccc gaaagggaaa actgacggcc attgcgaaaa
    12121 tacttttcct attccgtaac gcgccaggct gcctaatcct ccacctacaa aaacgatgat
    12181 caggttattc atggaagctg gctgtcggtt tcaaacagtt tagaaaggca ggtcgtccga
    12241 ctcgtcttca gtgaaagtgg ttacgggggg cagtggtgcg cctccggcat tgtgccctgc
    12301 gttgccgccg cttgctccgg ctttctcaac tttccaggcg cgcacttcgg tgtaccaacg
    12361 ggagttgtac tcgcggcttt ccacatcaat ggaagcggtt accgaatcgt tcacttgcag
    12421 attagcctga tcgatcttat caccccaaag cgaaatacat acttttttag ggtactgtga
    12481 ggggatttca agaatgaact cctgtttgcg ccacatcccg ttttttccct ggcctgtgac
    12541 ctcaggcagc aaagcaatga ctgttcctga tacttccatt gattaaatat gttttagtgt
    12601 ctggttcaaa aatggtttca aaaataaggc ttttgggtgt cgattgcaaa gcggaatgct
    12661 aatccgtacc gatggcctgg tcgagatcgg cgatcaggtc cgccacgtct tcgatgccta
    12721 cgctgaggcg tatcagcgtg tctttcagcc cgattttcag tcgttcctcg cgcggcatgc
    12781 ccccgtgcga catgctcgcg ggatgtgtgc aaagcgattc cacgccgccc aacgattcgc
    12841 cgagtgcgaa aatttgcagg ttttccatcg tacgcacggc tttttcatag ctgtcgtctt
    12901 gtagttcgaa agacaccacg ccaccgaagc cgcgcatttg tttcgctgcg agtgcgtggc
    12961 cggggtgatc gggcaggccg gggtaataca cttttcctac tttgggatgc gcattgagcc
    13021 acgtggccac ctgaacggca ttttcgcaat gacgctgcat gcggatgtgg agcgttttga
    13081 ttccccgtaa taccagaaag caatcctgcg ggcctggtac cgcaccgctc gcattctgaa
    13141 tgaatttcaa ccggcccgcg aggtcgtcgt cgctggtgac caatgcgccc atcaccgtgt
    13201 cggaatggcc gccaaggtat tttgtcaccg aatgcatcac gatatccgcg ccaaggtcta
    13261 gcgggttttg caggtagggg gaagcgaagg tgttgtcgac gcaggttaat acatttcttt
    13321 cgcggcaaac gcaggtaatg ctttcaatat cgatgatttt cagcagcggg ttggtcggtg
    13381 tttcgagcca gaccaggcgt gttttgtccg ttattaactg cgctatgtta tcagtttcat
    13441 caatatcgat gaacctgaat accagtccca gcggctcgaa aatgcgtttc atgaggcggt
    13501 acgtaccgcc gtagatgtca ctaggtgcga tgatttcgtc gccgggatgg aaaagtttca
    13561 ggaccgcgtc cgtggcggcg aggccggagg cgtaggcgag gccgtgtttg ccgttttcca
    13621 atgcggccag tgcggtttgc aaggcggtgc gcgtcgggtt gctgctgcgg gcatattcat
    13681 agcctttgtg cttgccgggg ctttcctgta cgtaggtgga agtctggtaa atcggcgtca
    13741 taatggcgcc ggtacccggg tccggttcga tgccggcatg tatggctttg gtggcgaatt
    13801 tcattttttt ggtggtggca aatattaatg cagaaaagca agttcacaaa aaccttttgt
    13861 caaaacaact ggttattcaa ataggaaagt aaaccggatt agccttggaa acgtctacac
    13921 caaaaagatt ctcacttccg gtcgtcgtaa gcatattaat gacgatcgta ccattggtga
    13981 cgacctctat cctgacggcc tgggcgatca atcaagagaa agtccttcgc gagcttccta
    14041 tcgaatggtg gctcggcgtt acgttcatcc tcacgctggc gtccgcttcc gcgctcacgc
    14101 cgcctacatt tcttgcattg gtttacgggt atttcctcgg ctgggcgtcg gtgccgatgc
    14161 tttttgcttt gaacatcggc gcgatcgcca ttatatatgt atcggcgcat ttcctgcatg
    14221 cggcttccgt gcggaattac ctcattcagg tgtatccgca ggtgggcaca ttgctgagaa
    14281 ggttttataa gaatgagttg cggctgatct tcttcgcgaa actgtcgccc gtgctgccgt
    14341 tcgccattac aaatttgttt ttcgcgatgg ccggcgcgcg gttcaagcag gtgctgacgg
    14401 gcggaacgtt gggtatgatc ccgcgcacgt tgctggccgt ctgggcgggt aaggaggcgc
    14461 aggatatccg ttacctgctc gaacacccga atgaaggatt agctaccaaa attgtgctga
    14521 tcgccctgat cgtcgtttca accgtgggga tcggttattt cttcaaagac aagagtatgg
    14581 tagaatcatg agcgcgatac aaggctatct gccggttgct ttggtaatat cgtacaataa
    14641 taagctacaa aacgccacaa aaccatcaac ttcatcctgt ttctttgtgg taaagttata
    14701 attacccgaa aagtagaatg aaatccttac ctttcattga tctcctcatc gtgatcgcct
    14761 atctggcggg aatggttgcc gtaggggttt acttttcgag aaagaatacc aatgccgaac
    14821 agtttaccaa agcctcgggc cgcattcccg gctgggccat cggcatttcc atctacgcaa
    14881 cgtttttgag cagcaatact ttcctcggcg tgccgggcaa ggcattcggc agcaactgga
    14941 gttctttcgt tttcagcctg tcgatgccgt tcgcggcgtg ggttgccaca aagtttttca
    15001 taccatttta cagaagtact ggcgaggttt cggcctacac gcacctcgaa caccgtttcg
    15061 ggccgtgggc gcgcacttat gccgtgatct gtttcctgct cacgcagctc gcacgcatgg
    15121 gctcgatctt cttcggcatt gcattgagct tgcaggcgct gaccggctac ccgatgtcta
    15181 cgatcatggt ggtggtgggc atttgcattg tgctgtacac ggtgatgggc ggcatggagg
    15241 cggtgatctg gacggaagta gtacagggcg tgatcaagac gatcggtgcg ctcgtgatcc
    15301 tttacctcgt cgtgaccggg gtttccggcg gtatgccgag cattatcgac attggtaagg
    15361 ccaatgacaa attcagtctc ggaacgctgg caccggattt tacgcaagca tcgttttggg
    15421 tgatcctgct ttacgggttt tttatgaacc tgaacaattt cgggatggat cagaactacg
    15481 tacagcgcta ccataccacg tcgtctgtca aagaagcggc gagctccgta tggctttgcg
    15541 tgtacctgta cgtgcccgtc tcgctgatat tctttttgct cggaacctgc ctttttgcct
    15601 attaccaggg taacccggag ctgctgcaaa ccattaaaat gcaggtagca gccgaaaagc
    15661 tgccgggcgc aacgtcggag gcgattacca acctggcggc aacgctcacc ccggccgatt
    15721 atggcgacaa ggtcatgccg catt
//
