LOCUS       c00001_NZ_JAJF..       25362 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAJFOJ010000001.1 Roseburia inulinivorans DSM 16841 strain
            FDAARGOS_1587 ctg.s1.000000F_arrow_pilon, whole genome shotgun
            sequence.
ACCESSION   c00001_NZ_JAJF..
VERSION     c00001_NZ_JAJF..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:31:07
            Original ID  :: NZ_JAJFOJ010000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2186569
            Orig. end    :: 2211931
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25362
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2196569:2201931]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15362
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..25362
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25362
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="acetate2butyrate"
                     /region_number="4"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             complement(1762..2370)
                     /locus_tag="ctg1_2026"
                     /transl_table=11
                     /translation="MIIIRGLNKAFGEKIIFSNFNLEIPDGSFVVISGDSGSGKSTLLN
                     MIGGIEKPDSGSIIIEGLNITRLKNKNSFFADTVGFLFQNFALLENKTVKENLSLIKKS
                     SRTKVSLKEALNRVGLSKEVNKKVYQLSGGEQQRVALARLMMKKCSVVLADEPTGSLDK
                     KNRDIVMRLLHELNEEGKTVIIVTHDQGIIEDEPYVVKI"
     CDS             complement(2367..4331)
                     /locus_tag="ctg1_2027"
                     /transl_table=11
                     /translation="MKHIRNILLLITIIFAFVMQAEVYQNMLWNFNGAYYLSSRYTTTN
                     DDMDSFLANAEDTAEKHGVHIFSTFNQRVSNYQTRLYIYGDDTVVRDSLKSTMDIEEKT
                     YTALIGGITVIEFEDFREVKNTGNGQEIMISYIGDDDDIIATYQDLAKEYSISQPEFWQ
                     STETDMMFIVWGLVAILMIVLNVIEVIRRQKEVVVRASLGENAAVLALKAVVADMISYA
                     ALFVLAKLLVSQFISGAYEDYLILAVYCAGAVLSVIPYAAFVCFDVKKAFANASDKKGM
                     FYLLNGLKVFATAMTIFTITTNLSSIQGNLLTNTTLLENHYNDYYFGVMQLEPPFEENE
                     EESTESKFWNDLYENEYNTINPVVCIGSRISDTDNYIFVNHNARDMLQGFSDMLTEDDE
                     KEDIVVFVPKGRNAESYKDIAKEEIGSLTQNAEELRVVYKEYSGREQFYYLNSNREEAI
                     DGLSRVTNPIVIYQANEAVALNGSYIETGTYNSEVIYGCDESTIRNAAKKYAEQLDSHY
                     FMLTNVGEDYIYSHSFLVKLISFISSLCVLVLLLDIAIIVSEAKMEFRLSSMEISLKKV
                     LGYSFYERHKRFISVNLIENIAGVILICIVSIFISNASVGIALLIGSLLTIIEMAIIFT
                     NIMWVEKTNISKSLKGGCL"
     CDS             5217..6788
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_25"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2028"
                     /sec_met_domain="Glyco_hydro_25 (E-value: 1e-28, bitscore:
                     98.0, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFDDDLEFESLNNEPRDTRFILPIIIVAVLLVIVIVALVLLGK
                     NSKNKDTSADLMSTEQSETTETETQTTEVMGNIATTESTEEVEADDPQNGNMGTDTGAS
                     VDVTALLSAGNVTESGETTFGIDVARYQGTIDWSQVAASGVQFAMIRVGYRTQKTGEIV
                     ADTNAKYNMQEAQANGIKIGAYFFSTAVTTDEAVQEADWVADYISQYQITYPVAFNCEG
                     FENADSRQYAMTQSERTDIAIAFLNEIYNRGYTPMFYAAKNEMLGDAKWDTSRIEKTYK
                     IWVSQYPSVPYPQTAQSDYTGTHAMWQYTNQGTVAGISKPVDVDIAYFGYEGTADAKSD
                     VTPETVSADAEALMNFSDVNETVTAKQSTNLRNIPSQGSDATVVATLQNGETATRTGVS
                     SSGWSRVSYNGQTLYAVSSYLTTDLGYTAPAANTTAETTAADGSGSGDGLKTKFTACND
                     VVTAKIEVNLRTLPSVTNPDAAVAAVLKNGETVTRTGINTDYGWSRVDYNGQTLYCVSS
                     YLTSAQ"
     CDS             complement(6860..8182)
                     /locus_tag="ctg1_2029"
                     /transl_table=11
                     /translation="MQFVRSQDLKPGMRLAKPIYNKMGVLLYERNTKLTLQSINSIDNF
                     GLIGIFILEPAEPVPPLSKEDLEFEQFQTIYMFKLKDCMDKLLAQKNIPAITELVQNIY
                     THYGALDHKLNFTQNLRSSADFVYKHSISVAILSAMIANEMHIELEDSQSLIAASLLYD
                     FGYLSVPKSILDKNEDLSASDRDLIQLKSEHGYEIIRPHFAELGLNDTSLEIIQNIIFE
                     DHATISPRPPKSPVQLLIDILKAADKFDRLTAMNINHAPMSELAAMTFFYSHIAEYNRS
                     VITALADSIQILPTGACLDFANGEKGLVLADNPADFLHPMILNFKDNRIYDLSDPETSD
                     QLQIVDIMKTMDNRIAIDSDTLKHFVADPYIKATADRFRAQKEKISRRKNGTSAIPHAK
                     QPVMDKPVLPASPVSAVSIASRNEVTPPVKKQRPAKRKKLI"
     CDS             8281..9540
                     /locus_tag="ctg1_2030"
                     /transl_table=11
                     /translation="MVLERNFLGADAGIFRQNEVLMKKIPLKRIFAAAALVCCLTVTTA
                     YADVTQEDIDNAKNQINNLKNQQKDAQDAVDDINGKKGQLESDLNNLNGQMTNIVSSMN
                     ALESQINDKKKELSDLEDEIDQTQDNLEAAKQQSASQYEDMKIRIRYMYENGNTPMLEM
                     LLSASSFSDFLNRTEYISEINSYDRQKLEEFIQVQEQIAAEEASLEEQKKDLESEQQEL
                     LAMQDDMKVKQNSVNSLISSTQANISQTNSELSSAQGKVNDINSQIAQMEELEKQLEIQ
                     KAKEDAARMAEIKRQEAENNGEFSYVPSDSDLYLLGAIIQCEADGEPYEGKLAVGSVVM
                     NRVRSSYFPNTVSGVIYQSGQFSPVASGRYALRLEQGVNNTCMQAAQEVLNGNITNSCL
                     YFRTVIDGLEGTIIGHHIFY"
     CDS             10001..11182
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2031"
                     /sec_met_domain="Thiolase_N (E-value: 5.9e-95, bitscore:
                     314.7, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 7.1e-49, bitscore:
                     161.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARKVVLAGACRTAIGKMGGALSNTPAADLGAIVIKEALRRAGVK
                     PEMVDEVKMGCVIQAAQGQNVARQASIKAGLPIEVPAITINVVCGSGLKCVNDAATMIM
                     AGEADIVVAGGMENMSMAPYAMTKARFGYRMNNATIIDTMVNDALTDAFNHYHMMITAE
                     NVCDKYGITREELDEFSANSQQKCEKAIAEGKFADEIVPVPVKVKKEIVDFVTDEGPRA
                     GTTAESLAKLKCCSGKEGGLVTAGNASGINDGAAAIVVMSEEKAKELGVTPMATWVAGA
                     LGGVEPEIMGVGPVASTKKVLAKTGLTIDDMDLIEANEAFAAQSIAVARDLHFDMSKVN
                     VNGGAIALGHPVGASGCRILVTLLHEMQKRDSHRGLATLCIGGGMGCSTIVER"
     CDS             11278..12150
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2032"
                     /sec_met_domain="HCDH (E-value: 4.2e-33, bitscore: 111.1,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 9e-60, bitscore: 198.8,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGVIGAGTMGQGIAKAFAQVEGYEVALCDIKQEWADGGKAKIQ
                     KGYARLVEKGKMTQEAVDAILAKITPGLKEDLCADCDLIVEAAFEDMGVKKTTFQELDK
                     IAKPECIFASNTSSLSITEIGNGLTRPMVGMHFFNPADRMKLIEVIAGVNTPDETVEAI
                     KKISVEIGKTPVQVNEAAGFVVNRILIPMINEAAFIKMEGVSDIAGIDAAMKLGANHPM
                     GPLELGDFIGLDICLAIMDVLYKETGDSKYRACPLIRKMVRGGNLGAKSGKGFYVYNAD
                     RTKTPVDAQ"
     CDS             12186..13340
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2033"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.2e-50, bitscore:
                     166.8, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.2e-29, bitscore:
                     97.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.2e-39, bitscore:
                     131.9, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTLDKKHEMARSLFREFAENEVKPLAQETDETEQFPAETVKKM
                     AKYGFMGIPVPKEYGGQGCDPLTYVMCVEELSKVCATTGVVVSAHTSLCIDPIMTYGTE
                     EQKQKYVRPLATGEKLGAFALTEPGAGTDAQGAQTKAVLDGDEWVLNGSKCFITNGKVA
                     DVYIVIAITSITEDKRGRKKKNFSAFIVEKGAPGFSFGTKEKKMGIRGSSTYELIFEDC
                     RIPKDALLGPEGKGFPIAMHTLDGGRIGIASQALGIAEGALERAIAYTKERKQFGRSIA
                     QQQNTQFKLADMATRIEAAQMLVYKAAMAKANQKVYSVEAAKAKLFAAETAMAVTTEVV
                     QLFGGYGYIREYDVERMMRDAKITEIYEGTSEVQRMVISGALLK"
     CDS             13507..14289
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 157.9;
                     E-value: 8.2e-49)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2034"
                     /sec_met_domain="ETF (E-value: 3.3e-47, bitscore: 157.9,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVVCIKQVPDTKGGVKFNPDGTLDRAAMLAIMNPDDKAGLEAA
                     LRIKDETGAKVTVLTMGLPKADAVLREAMAMGADDAILVTDRVLGGADTWATSTTIAGA
                     LRNLDYDLIITGRQAIDGDTAQVGPQIAEHLGLPVISYAADIKVDGDSVIVKRQYEDRY
                     HELKAKMPCLVTALSELNQPRYMTPGGIFDACDKEVTVWGRADLKDVDDSDLGLKGSPT
                     KIAKASDKVAKGAGEKVNLDPAESVAYLIGKFKEKHII"
     CDS             14307..15362
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 164.3;
                     E-value: 9e-51)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2035"
                     /sec_met_domain="ETF (E-value: 3.6e-49, bitscore: 164.3,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 1.3e-36, bitscore:
                     121.7, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNKMSLEEYKGVFVFAQQVDNVLDGVAFELLGKGKDLAKDLNTEV
                     TAVLIGSGVKGLADQLAEYGADRVIVVDDPELKEYRTEPYAHALASVINEYKPEIMLVG
                     ATAIGRDLGPTVSARVKTGLTADCTSLEIGDFPLVAAPGKESEQKHNQLLMTRPAFGGN
                     TIATIACPDNRPQMATVRPGVMQKIAPIAGAKANVVEFNPGFTPDNRYVEILNVVKAVK
                     STANIMEAKILVSGGRGVGSKENFKLLEDLAEVLGGTVSCSRAVVENGWLPVDLQVGQT
                     GKTVRPQIYFAIGISGAIQHVAGMEDSDLIIAINKDEDAPIFDVADYGLVGDLNKIVPA
                     LTAALKTELGK"
     CDS             16124..17413
                     /locus_tag="ctg1_2036"
                     /transl_table=11
                     /translation="MQTNNSKEKVRQLQNKLYLTAKKCDSRRFHALYDKVYRDDVLFEA
                     WKRVKANKGSSGVDGIGIEDIEEMGIEKYLSEIKSELMDGKYKPSPVKRVMIPKPDGSE
                     RPLGIPTVKDRIVQMATKIAIEPVFEADFRDCSYGFRPKRSARQALEVVRKACNNKGYY
                     VVDADIEKFFDNVNQDKLMKLAEQRISDRRILKLIRQWLVSGVLYGNVLTISELGTSQG
                     AVISPLLANIYLNTLDRLWEKYGLTHGILVRYADDTVIICKNKKNANHALNLLQYIMAK
                     LDLKLHPVKTKIVSMWDGKEGFDFLGMHHRRMTTETSKGQLYKETYQYPSRKAMKKMKA
                     EIKKNVNGRSLLVAKEEDLIKNLNPKIIGWKNYYSTKTNETWMQELDWYIICTFTRWYN
                     KKHQRCKHMSRVGFVRNSIYEKGLKKMARA"
     CDS             17932..18525
                     /locus_tag="ctg1_2037"
                     /transl_table=11
                     /translation="MNKNKFSTKYLVEMALLVAIILLMAFTPIGYIKTAGLEITLIVVP
                     VAVGAVTLGPTAGAILGGVFGITSFIQCFGMSQFGALLLGINPFLTFLVCVPTRILMGW
                     LTGLIYHGLRKTKIPSAASVTIASLCCPLLNTTFFMGTLVTLFASTMRESFGMGKVLPF
                     IFAFVGVNGVVEAIVCFVVGTAISMALKKALRYS"
     CDS             complement(18620..19126)
                     /locus_tag="ctg1_2038"
                     /transl_table=11
                     /translation="MKTDQYSILFSSLTGNTKKLADAIHETLPEEGCEYFGAIKTPVPS
                     SELLYIGFWTDKGNADNETLTLLSTLKNRRIFLFGTAGFGGSDAYFQKILGQVRQSIDP
                     SNTIIGEYMCQGKMPQSVRERYMKMKENPEHPANLDALIKNFDCALSHPDSDDLEKLRN
                     LCRLR"
     CDS             19400..20248
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2039"
                     /sec_met_domain="CbiA (E-value: 2.4e-12, bitscore: 44.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPENSSCSSASTCSRESCEGCPSKAKGGSGIAKEPMNKASNVKKV
                     IGVVSGKGGVGKSFVTSSLACAMNKAGYKVGIMDADITGPSIPKMFGVHGQVYGTEDGM
                     VPMAAENGIKIMSVNLLLDNEEDPVIWRGPVIAGVVKQFWNETVWGDIDYLFVDMPPGT
                     GDVPLTVFQSLPVDGIVVVTSPQELVQMIVKKAYNMANMMHIPVLGVVENFSYLECPDC
                     GKKINVFGQSHVDEAAQELGIPVFGKLPVDPAYAEKADEGKFFEIDNPYLAAGVETLKN
                     L"
     CDS             complement(20303..20866)
                     /locus_tag="ctg1_2040"
                     /transl_table=11
                     /translation="MDNQKLGIFITELRKEKGLTQAQLAQKLNVTDKAVSKWERGVGFP
                     DIKLLEPLADVLDISLLELMKSERLPKTTVSAPDTTDAFQNVIDLASYERKIERQRIAL
                     VTLFIVLLIALIFLVDIMQSFGFLFVCLPIILFFLGIWFLRLSHKKSTHKHAFLFAGLL
                     AFAYPLCLILLFCFAFALGGPVPN"
     CDS             21223..21684
                     /locus_tag="ctg1_2041"
                     /transl_table=11
                     /translation="MKIKIEIDEGLPEDEVLIRCRGLTEQISDVQKAVSEVINTSQKFV
                     FYRGNTEYYLTLDEILFFETDSDGINAHTRDNIYQTKYKLYELEELLPGSFMRISKSAI
                     VNTSHIYSISRNLTASSVVAFADTHKQVYVSRYYYKPLINKLEEKRLHQ"
     CDS             21681..22394
                     /locus_tag="ctg1_2042"
                     /transl_table=11
                     /translation="MKLRKNSGKILWGLFFILAAVYVVVSKLWIMPEISVFSVLLTVFF
                     IWLFLNGIRNVNFWEILFSIAFICIIYDDWLGITALTPWTVLGAALLGSIGLSLIFKKK
                     SGHSPSISFEFDSDSDNEDGKYIGENIKIDNNFGTAIKYVNSDNFCMADVDNSFGSLTV
                     YFDNAIIQSGSAKIKVDNSFGETNLYIPKEWKTENNLGQAFGSVKTHGVCEGSSNNTLK
                     LKGETSFGEINIYYI"
     CDS             complement(22553..23959)
                     /locus_tag="ctg1_2043"
                     /transl_table=11
                     /translation="MNEKNGAIRDASVLGVPKMLILGLQHMFAMFGATILVPILVNSYF
                     GEDVLHVQVTLICAGVGTLFFHLCSKFKVPAFLGSSFAFLGGFATIANLDTGVFADMSN
                     ADKLSYACGGIVVAGLLYLILALIIRLAGVKKVMRFLPPVVTGPIIICIGLSLSGSAIN
                     NASTNWLLAFIALATIIVFNIWGKGMFKIIPILMGVVVSYAAALIFNALGMTNADGSAI
                     LDFTNIASAAWVGVPKFSICKFNISAILVMAPIALASMMEHIGDMSAISATVGENFIED
                     PGLHRTLIGDGLATSLSALVGGPANTTYGENTGVLELSKVHDPKVIRIAALYAIILSFI
                     PKMAEVIGSMPSAIIGGVSFMLYGMISAIGVRNVVENHVDLTKSRNLIIAGVIFVCGLG
                     FSNGLTFTVAGTDITLTSLAIAAIAGILLNAILPGNDYHFGKDVEADSNRGIDMMPNLH
                     EDTSYGDHDE"
ORIGIN
        1 tcggaactga tggatggaaa gtataaacca tccccagtaa agcgagttat gataccaaaa
       61 ccagacggaa gtgaaagacc tcttggaata ccaacagtca aggacagaat tgtgcagatg
      121 gctaccaaga tagcaataga gccagtattc gaagctgact ttagagattg ttcctatgga
      181 ttccgaccga aaagaagtgc caggcaagca ctggaagtgg taaggaaagc gtgtaacaac
      241 aagggctatt atgtagtaga cgcagatatt gagaagtttt ttgataacgt aaaccaagat
      301 aaactgatga aactggtaga gcagagaata tcagaccgta ggatattgaa gctgataaga
      361 caatggttag tatcaggagt attatacgga aatgtactga caatttccga actgggaaca
      421 agccaaggtt cagttatatc tccgttattg gcaaacatct acttaaatac actggacaga
      481 ctgtgggaaa agtatggact tactcacggt attcttgtaa ggtacgcaga tgatacagtc
      541 atcatttgca agaataagaa aaatgcaaat cacgcactga acttattgca gtacatcatg
      601 gcaaaactgg atttaaagct acacccagta aaaacaaaga ttgtcagcat gtgggacgga
      661 aaagagggat ttgactttct tggaatgcac cacagaagaa tgacaacgga aacaagcaaa
      721 ggacaattgt ataaagaaac ttatcagtac ccgagcagga aagccatgaa gaagatgaaa
      781 gcagaaatca aaaagaatgt aaacggtcga agtctgttag ttgcaaagga agaggattta
      841 ataaagaatc taaatccgaa aatcataggt tggaagaatt attattccac caaaacaaat
      901 gagacatgga tgcaggaatt agactggtat attatctgca cctttacaag atggtataac
      961 aagaaacacc aaaggcgtaa acatatgtca agagtgggat ttgttagaaa tagcatttac
     1021 gaaaaaggat taaagaaaat ggctagagca tgacgtaatg ctgtagaaag aagaatgtcg
     1081 gaaagccgtg tgagggagaa cctcatgcac ggtttgatga ggggcggatg aaattttcat
     1141 ccgcctactc tacatggatg acttgtgaga ggacgcttat atttgcccaa tttacactgt
     1201 gaattgcacc acagaatctg caatttacgt tatggaactc acggttatgg agtgtctata
     1261 aaagaggtag gataagctgc tttgacttca tgaatattgt ttgtacaata atcacataaa
     1321 tcttcacttc ttatttgatt gtaatatgat ttggtttttt caatatccaa agtgttcacc
     1381 tcctcaaata agaatttaca aaatcattaa tatcatattc taccataatc acatatacaa
     1441 ttctatttta ttccattaaa atttattaaa aaacctaatt catttatttc atgagatgag
     1501 atttgtcaag ggcattttct gtgaggtgtt caaaactact aaatagttat ttagaaaaca
     1561 ctgtagtcca ttctatctgt taaaaagttc catacatcaa actatcgatt tcatctacaa
     1621 aacattttga acttacctaa taacttctga aaaaacaaaa aacctgtaga ttgtatctaa
     1681 taaaaagatg aaatctacag gttttcgttt ttactcgtat ttcagctaat gccgtcaatg
     1741 aatatcacag aaaatgaaag cttaaatttt tacaacataa ggttcatctt caataatacc
     1801 ctgatcgtgg gtaacaatga taaccgtttt accttcttca ttgagttcgt gcaataacct
     1861 cataacaata tctctatttt tcttgtcaag tgagccagta ggttcatctg ccaaaacaac
     1921 agaacatttt ttcatcataa gacgagctaa agcaactctc tgttgttcac caccggaaag
     1981 ctgataaact tttttgttaa cttcctttga taaccccaca cgattaagag cttctttaag
     2041 tgatacttta gttcggcttg attttttaat caaacttaaa ttttctttaa ctgtcttatt
     2101 ttcaagcagt gcaaaattct gaaaaagaaa ccccactgta tccgcaaaaa aactgttttt
     2161 atttttaagc cgggtaatat tcagcccttc gattatgata ctgccgctat ccggcttttc
     2221 gataccacca atcatattga gcaaagtgct ttttccactg ccgctatccc cgctgattac
     2281 tacaaaactt ccatccggaa tttccaaatt aaagttggag aaaattattt tctctccaaa
     2341 tgctttattt aagccacgaa ttataatcat aaacatcctc ccttcaatga ctttgagata
     2401 tttgtttttt caacccacat aatatttgtg aaaatgattg ccatttcaat aatggtgagc
     2461 aatgatccaa tcagtaaagc aatcccgaca cttgcgttag atataaaaat cgaaacaatg
     2521 caaatcaata tcacaccggc tatattttct atgagattaa cggaaataaa tcttttgtgc
     2581 ctttcataaa agctataacc taaaaccttt ttgagggaga tttccataga gctaagtcta
     2641 aattccattt tcgcttcaga tacgatgata gctatatcta acagcaatac taatacgcaa
     2701 agagagctta taaagctaat caattttaca aggaaactat gactataaat gtaatcctct
     2761 ccgacattcg tcagcataaa atagtgtgaa tcaagctgtt ctgcatattt tttcgcagca
     2821 ttacgaattg tgctttcatc gcatccgtag attacctcac tattatatgt tcctgtttcg
     2881 atataacttc catttaaagc aacagcctca tttgcctgat aaatcacaat cggatttgtt
     2941 actcttgaca atccgtcaat agcctcttct ctgttcgaat tgagataata aaattgctct
     3001 ctgccagaat attctttata aacaacacgc agttcttctg cattttgggt aagagagcca
     3061 atttcctctt ttgcgatatc tttgtatgat tccgcatttc ttccctttgg cacgaagacc
     3121 acgatatcct ctttttcatc atcttcagta agcatatcag aaaacccttg tagcatatct
     3181 ctggcattat gatttacaaa aatataatta tccgtatcgc ttatccggct gcctatgcag
     3241 accaccggat ttatagtgtt gtattcattt tcgtaaaggt cattccaaaa tttgctctct
     3301 gtagattcct cctcattttc ttcaaaagga ggttcaagct gcataactcc aaaataataa
     3361 tcattataat gattttctaa aagagtagtg tttgtaagta aattaccttg aatgctactg
     3421 agatttgtag ttattgtaaa aattgtcata gcagtagcaa atactttaag accattcaga
     3481 agataaaaca tacctttttt atctgaagca ttggcgaagg ctttttttac atcaaagcag
     3541 acaaaagcag cataaggaat tacggaaaga actgctccgg cacaatacac tgccaaaatg
     3601 agataatctt catatgcacc cgatataaat tgagaaacaa gcaactttgc taaaacgaat
     3661 aacgcagcgt acgaaatcat atcagccact acagctttta gagcaagcac agcagcattt
     3721 tcgcccaagg aagctcgtac aactacttcc ttttgtctgc gtatcacctc aatcacatta
     3781 agtacaatca tcaatatggc aaccaatccc caaacaatga acatcatatc agtttcggtt
     3841 gattgccaaa actctggctg cgatatagaa tattcttttg ccaaatcttg atatgtggca
     3901 atgatgtcat catcatcacc gatatagctg atcattattt cctgtccatt gcctgtgttt
     3961 tttacttctc taaaatcttc aaattctatt acggtgattc cacctattaa agccgtatat
     4021 gttttttcct caatatccat cgtgctttta agactatccc gaacaacggt atcatcacca
     4081 taaatataaa gtcttgtctg ataattagaa actctctgat taaaagtcga aaaaatatga
     4141 acaccatgct tctcagctgt atcttctgca ttggctaaaa atgaatccat atcgtcattg
     4201 gtagttgtgt atctggacga taaataataa gcaccattaa agttccatag catattttga
     4261 tatacttcag cttgcataac aaaagcaaaa ataatcgtaa tcaacagcaa tatatttctt
     4321 atatgtttca ttcaaatccc tccaatttca tttggcatag ttaaattcaa atcatccaaa
     4381 agcatcaaag tttttctgta attgcctttt gctttttata aaaatatttt ccctttcaga
     4441 cattttgagg gttcgattta gtacagcttg cccccaacaa ctcaataaat attataaaca
     4501 aagctgtaaa tgaaatcaat cttttgttcc tgtttaaaat tcattaaaaa aaccttaatt
     4561 catttatttc aagaatgcag attgagtttt aatcctatag acactcatcc cataatcgtg
     4621 agttccataa cgtaaattgc agattttgta gtgcgcttca tagcataaat tgggcaaata
     4681 taagcgtcct ctcacaagtc attcgtaacg taaatgaaag aaaaacggtg cagacaaata
     4741 tgatttcctt tgtgagccat ggagctggga ttctaacaat catggaagct tcagctgaac
     4801 atgattgttg ttcagaagcc cagcggaatg cctggcgaac aggaacatca catttcgtct
     4861 gtaccgtttt tcttttcata aacctataaa atcacgactt gcgagagaac gcttatatct
     4921 gcccttcaca acctgtaaaa gcaccacaga atctgcgaca ctacgtccgt caaactccgg
     4981 tttaaaacat ttatttcgat aatgaaaata taaattagtt gctggcgggt tttgaaaaag
     5041 tatagcgcac taagtgaaaa tatggtattg ttaccgtgta atagcatata tgacaatcgt
     5101 attatcagat acgcatacaa catctgaaat acagagagtg tagcttgtga tttcctaatt
     5161 atgttagaat aaatgaaaaa caagctatat aatgggaaga aggaaggaaa cagattatga
     5221 agaaatttga tgatgatctt gaatttgaat cattgaataa cgaaccgcgg gatacccgct
     5281 ttatattacc aattatcatt gtggcggttt tgcttgtcat tgtgattgtg gcactggttt
     5341 tgttaggaaa aaatagtaaa aataaagaca caagtgctga cttaatgtct acagagcaga
     5401 gtgagacaac agagacagaa acacagacca ccgaagtaat ggggaatatt gccacaaccg
     5461 agagcactga agaagtggag gcagacgatc cacagaatgg taatatggga actgacacgg
     5521 gagcgagcgt tgatgtgact gcactgttat cggcaggaaa tgtgacggaa tcgggtgaga
     5581 caacctttgg tatagatgtg gccagatatc agggaaccat cgactggagt caggtggcgg
     5641 cttccggggt acagtttgcc atgatacgtg tcggatatcg cacgcagaag actggcgaga
     5701 tcgttgcgga taccaatgca aaatacaaca tgcaggaagc gcaggcaaat gggataaaaa
     5761 taggggcata cttcttttcg acagccgtca caacggatga agcggtgcag gaggcagact
     5821 gggtggcaga ttatatttcc cagtatcaga tcacctatcc ggttgcattt aactgtgaag
     5881 gatttgaaaa tgcagacagc agacagtatg ctatgacaca gtcggagaga actgacattg
     5941 cgatcgcatt tttaaatgag atttataacc gcggctacac gccaatgttt tatgcggcaa
     6001 aaaatgagat gcttggcgat gcaaaatggg atacttcaag gattgaaaaa acatataaaa
     6061 tctgggtgtc tcaatatcca tctgtaccgt atccacagac tgcacagtcc gattacactg
     6121 gaacgcacgc aatgtggcag tataccaatc agggaacagt ggcagggatc agtaagccgg
     6181 ttgatgttga tattgcctat ttcggttatg agggaactgc agatgcgaaa agtgatgtga
     6241 caccggaaac agtcagtgca gacgcagaag cattgatgaa tttctccgat gtaaatgaaa
     6301 ctgttacggc aaaacagtcc acaaatctca gaaacattcc gagtcagggc tccgatgcaa
     6361 cggttgtggc aaccctgcag aatggcgaga cggcgacaag aaccggcgta agcagcagtg
     6421 gctggtcaag agtaagttac aatggacaga ctttatatgc agtgtccagt tatctgacga
     6481 cagatcttgg atatacagca cctgcagcca atacgactgc agagacaaca gcagcggacg
     6541 gctcaggatc cggagacgga ctgaaaacaa aatttactgc atgcaatgac gtggtaacag
     6601 cgaagatcga agtgaattta agaacacttc cgagtgtcac aaacccggat gcagcagttg
     6661 cggcagtttt aaaaaatggc gagaccgtga cgagaaccgg aatcaataca gactatggct
     6721 ggtcaagagt tgactataat ggacagacac tgtactgcgt gtcaagttat ctgacaagtg
     6781 cacagtaaaa aagaagctgg tgcattcaga cgaaaaagat gtaacgtctg aatacatcag
     6841 cttttttatg ctatgcacat caaattaatt ttttcctctt tgctggacgc tgtttcttta
     6901 caggaggtgt tacctcattt ctggaagcaa tggatacggc tgaaactggt gacgcaggca
     6961 ggacaggttt gtccataacc ggctgttttg cgtgcggaat ggcagatgtt ccatttttgc
     7021 gacggctgat tttttctttc tgggcacgga aacggtcagc ggtcgcttta atatatggat
     7081 ctgcaacaaa atgcttaagt gtatcgctgt ctatggcgat acggttatcc attgtcttca
     7141 taatatctac aatctgtaac tgatccgagg tttccggatc gctcagatca taaatccggt
     7201 tatccttgaa attcaggatc ataggatgca gaaaatcagc cggattgtca gcaagcacca
     7261 gacctttttc tccattggca aaatcgagac aggcacctgt aggaaggatc tggatgctgt
     7321 ctgccagagc ggtgatcaca gaacggttat attctgcgat gtggctgtaa aaaaatgtca
     7381 tggcagccag ttctgacatt ggtgcatggt taatgttcat ggcagtcagg cggtcaaatt
     7441 tgtccgcagc cttcaaaata tcgatcagaa gctggactgg tgattttgga ggtcttgggc
     7501 tgatcgttgc atggtcttca aatataatgt tctggatgat ctcaagactt gtgtcattta
     7561 agccgagttc tgcaaaatgc ggacggatga tctcataccc atgttctgat tttaactgga
     7621 tgagatcccg gtcggaagca gagagatctt cgttcttatc taaaatgctc tttggaacgg
     7681 agagataacc aaaatcatat aataaagaag ctgcgatcag cgactgggag tcttccagct
     7741 caatatgcat ctcatttgcg atcatcgcag agaggatcgc aacactaatc gaatgcttgt
     7801 atacaaaatc ggcagaactt ctgaggttct gtgtgaaatt aagtttgtgg tctaatgcac
     7861 cataatgtgt gtatatattc tgtacgagtt ccgtgattgc cggaatattt ttctgtgcga
     7921 gaagcttgtc catgcagtct ttcaatttga acatatagat agtctggaac tgctcaaatt
     7981 caaggtcttc tttggaaaga ggaggaacag gctccgccgg ttccagaata aaaatgccaa
     8041 tcagaccgaa attatcaata ctgtttatac tctgaagtgt taattttgtg ttgcgctcat
     8101 acaataaaac ccccatttta ttgtaaatgg gttttgccag ccgcattccc ggctttaaat
     8161 cctgtgatct tacaaactgc atatatcccc atacctttcc tgatgcaaat atgataaaat
     8221 aaaaacaagc tgatacatac caaatatagc atattgaaag gttaaataca atctgctatc
     8281 atggtgcttg aaagaaattt tttaggagca gatgcaggaa tatttcgaca gaatgaggta
     8341 cttatgaaaa aaatcccctt aaaaagaata tttgcagcgg cagcattagt gtgctgtctt
     8401 accgtgacaa cagcttatgc agatgtcacg caggaagata ttgacaatgc aaaaaatcag
     8461 atcaacaatc tgaaaaacca gcagaaagat gcacaggatg cggtcgatga tatcaatgga
     8521 aaaaaaggcc agctagagag cgacctgaac aatttaaatg gacagatgac caacattgtt
     8581 tcgtccatga atgcccttga gtcacagatc aatgataaga aaaaagaact gtcagatctt
     8641 gaggatgaga tcgatcagac gcaggataat ctggaagctg caaagcagca gtcagccagc
     8701 cagtatgagg atatgaagat acgtatccgc tatatgtatg aaaatggaaa tacaccgatg
     8761 cttgagatgc tgttatcggc atcatccttt tctgattttc tgaaccggac ggagtatatt
     8821 tcggagatca attcgtatga cagacagaaa ttagaggaat ttatccaggt gcaggaacag
     8881 attgcggcag aggaagcttc tcttgaagaa cagaagaagg atctcgagag tgagcagcag
     8941 gaactgctcg ccatgcagga tgacatgaag gtaaaacaga attctgtaaa cagccttatc
     9001 agttcaacgc aggcaaatat cagccagacc aattctgaat tgagcagcgc ccagggaaaa
     9061 gtcaatgata tcaacagtca gatcgcacag atggaagaac tggaaaaaca gttagagatc
     9121 cagaaggcaa aagaagacgc tgcgagaatg gcggagatca agcgtcagga ggctgagaac
     9181 aacggcgaat tttcttatgt cccaagtgac agtgatcttt acctgttagg tgcgatcatc
     9241 cagtgtgagg cagacggtga accatatgag ggaaagcttg cagtcggaag tgttgtcatg
     9301 aaccgtgtgc gaagctctta tttcccgaat accgtatccg gtgtgattta tcagagcgga
     9361 cagttttctc cggtagccag tggacgatat gcgctccgcc tcgagcaggg agtcaataat
     9421 acctgtatgc aggcggcaca ggaggtgctt aacgggaaca tcacaaacag ctgtctctat
     9481 ttcagaactg tgatcgacgg attggaagga acgatcatcg gacatcacat attctactaa
     9541 tacggctgtc aatgcgcaaa ttacataaaa atcatttttg aaaccaaatg gaaaaagaga
     9601 cgtttttgtg agaaatatac aaaaaacgtc tcttttttgt ggaattgagc ggttgcgcat
     9661 gataattttt taacgaaaaa cagtatataa aataggtaaa aaccaaattt aaatactgaa
     9721 aaaagtgtga aaaaaaaaga aagctattgc atttgaaaat aaaatatggt agcatgagaa
     9781 agtactgaaa agccaataaa aaagccgaat acataaaaac gtagaaaatc aggaaaaaga
     9841 aaatttaaat ttaaaagaag aaattttaga tttatttttt ttactaaaag attgttaaaa
     9901 aaataacaac gtttttcggc agatttatta tgaaggaaac aaaatatact gcatattatg
     9961 agcggtgttt tgtaccacaa aaccgaaggg agaattcaaa atggcaagaa aagtagtttt
    10021 agcaggcgca tgccgtacag caattggtaa aatgggtgga gcattaagca atactccagc
    10081 agcagactta ggtgcaatcg ttatcaaaga ggcattaaga agagcaggtg ttaaaccaga
    10141 gatggttgac gaagttaaaa tgggttgtgt aatccaggca gctcagggac agaacgttgc
    10201 acgtcaggct tctatcaaag caggactccc aatcgaagtt ccagcaatca caatcaacgt
    10261 tgtatgtggt tctggtttga aatgtgtcaa tgatgcagct accatgatca tggcaggaga
    10321 agctgatatc gttgttgcag gtggtatgga aaatatgtca atggcaccat atgctatgac
    10381 aaaagcccgt ttcggatatc gtatgaacaa tgcaacaatc atcgatacaa tggttaacga
    10441 tgcattaaca gatgcattca atcattatca tatgatgatc acagcagaga acgtatgtga
    10501 taaatatgga atcacaagag aagaattaga cgagttctca gcaaacagcc agcagaaatg
    10561 tgaaaaagcg atcgctgaag gtaaatttgc agatgagatc gttccggttc cggttaaagt
    10621 gaaaaaagag atcgtagatt tcgtgacaga tgaaggacct cgtgcaggta caacagcaga
    10681 gtctttagca aaattaaaat gctgctctgg taaagagggt ggacttgtta cagcaggtaa
    10741 cgcttccggt attaatgatg gtgcagcagc aatcgttgtt atgagcgaag agaaagcaaa
    10801 agaacttggt gttacaccaa tggctacatg ggtagccgga gcacttggcg gtgttgaacc
    10861 agaaatcatg ggtgttggac ctgttgcttc cactaagaaa gtattagcta agacaggact
    10921 tacaattgat gatatggatc tgatcgaagc aaacgaagct ttcgcagctc agtctatcgc
    10981 agttgcaaga gatttacatt tcgatatgtc caaagttaac gttaatggtg gtgcaatcgc
    11041 acttggacat ccagtaggag cttccggatg ccgtatcctt gtaacattat tgcatgagat
    11101 gcagaagaga gattcccaca gaggtcttgc tacattatgt atcggtggcg gaatgggatg
    11161 ctctacaatc gttgagagat aattaatcag acaaaactgt ccggaaagcg ggtgactgct
    11221 tttccgggcg tttccattac atattaaaaa ttcagaatga attcaggagg tactaacatg
    11281 aaagttggtg ttattggtgc aggaaccatg ggacagggta ttgcaaaagc atttgctcag
    11341 gtagaaggat atgaggtagc tctctgcgat attaagcagg aatgggctga cggcggaaaa
    11401 gccaaaatcc agaaaggtta tgcaagactt gtagaaaaag gaaaaatgac acaggaagct
    11461 gttgatgcta tccttgctaa aatcactcca ggattaaaag aagacctttg cgcagactgc
    11521 gatctgatcg tagaagcagc attcgaagat atgggagtaa agaaaacaac attccaggaa
    11581 ttagataaga tcgcaaaacc agagtgtatc tttgcttcaa atacatcaag cctttccatc
    11641 acagagatcg gaaatggtct tacacgtcca atggttggta tgcatttctt caaccctgca
    11701 gaccgtatga aattaatcga agttatcgct ggtgtaaata caccggatga gactgttgaa
    11761 gctatcaaga aaatctctgt tgagatcgga aaaacacctg tacaggtaaa tgaagcagca
    11821 ggattcgttg taaaccgtat tttaatccca atgatcaacg aagcagcatt catcaaaatg
    11881 gaaggtgtat ctgatatcgc aggtatcgat gcagctatga aacttggtgc aaaccatcca
    11941 atgggaccat tagagttagg agatttcatc ggtcttgata tctgccttgc tattatggac
    12001 gttctttaca aagagactgg cgacagcaaa taccgtgcat gcccattgat ccgcaaaatg
    12061 gttcgtggtg gtaaccttgg tgctaagagc ggaaaaggat tctatgtata caatgctgac
    12121 cgcacaaaaa caccagttga cgctcagtaa ttaacagata ttaaggttta ggaggatttg
    12181 aaatcatgga tttcacttta gacaagaaac atgaaatggc gcgttctctg ttcagagaat
    12241 tcgctgaaaa cgaagtaaaa cctcttgcac aggaaactga tgagacagaa cagttcccgg
    12301 cagagacagt taagaaaatg gcaaaatatg gattcatggg aatcccggta ccaaaggagt
    12361 acggcggaca gggatgtgat ccattaacat atgttatgtg tgtagaagag ttatcaaaag
    12421 tttgcgctac aacaggtgtt gttgtttccg cacatacttc tctctgcatc gatccaatta
    12481 tgacttacgg tacagaagaa cagaaacaga aatatgtcag accacttgct acaggcgaga
    12541 aacttggtgc tttcgcattg acagaaccag gtgctggtac agatgctcag ggtgctcaga
    12601 caaaagctgt tttagacggt gacgaatggg tattaaacgg atcaaaatgc ttcattacca
    12661 atggtaaagt tgcagatgtt tatattgtaa tcgctatcac aagcattaca gaggacaaga
    12721 gaggaagaaa gaaaaagaac ttctccgcat ttatcgtaga aaaaggtgct ccaggattct
    12781 ccttcggaac aaaagagaag aagatgggta tccgtggatc ttctacctat gaattaattt
    12841 ttgaagactg cagaattcca aaggatgcgt tacttggacc tgaaggaaaa ggattcccaa
    12901 tcgctatgca tacattagat ggtggacgta ttggtatcgc ttcccaggca cttggtattg
    12961 cagaaggtgc attagagcgt gcaattgctt atacaaaaga aagaaagcag tttggtcgtt
    13021 ctatcgcaca gcagcagaat acacagttca agttagctga tatggcaaca agaattgaag
    13081 ccgctcagat gttagtttat aaagcagcaa tggcaaaagc aaaccagaaa gtttactctg
    13141 tagaagctgc aaaagcaaaa ttattcgcag cagagacagc aatggctgtt acaacagaag
    13201 ttgttcagtt attcggtgga tatggataca tcagagagta cgatgtagag cgtatgatgc
    13261 gtgatgctaa gatcacagag atctatgagg gaacaagcga agtacagcgc atggttatct
    13321 caggtgcatt gcttaaatag acgtgatcta gcggattgaa aatggatgga agaaatatag
    13381 aatcacgctt gcgagaatga aatatttctg acagacattt gagagcgcaa cgcgcacgag
    13441 aaacacgaag tgtttcgagt aatccgcgat taatgaaaat ataataacat aaggagtgga
    13501 aaatacatga atatcgtagt atgtattaaa caggttcctg atacaaaggg tggagtaaaa
    13561 ttcaatccag atggaacact tgatagagca gcaatgcttg ctatcatgaa cccagatgac
    13621 aaagcaggtc ttgaagcagc attaagaatc aaagatgaga caggagcaaa agttacagtt
    13681 cttaccatgg gacttccaaa ggctgatgca gttcttcgtg aagcaatggc aatgggagca
    13741 gatgatgcaa tccttgtaac agacagagta ttaggtggag cagatacatg ggcaacatct
    13801 actacaatcg ctggtgctct tcgtaactta gattacgatc ttatcatcac aggacgtcag
    13861 gctatcgatg gagataccgc acaggtagga ccacagatcg ctgagcatct tggtttacca
    13921 gttatctctt acgcagcaga catcaaagtt gatggagatt ctgttatcgt taagagacag
    13981 tatgaagaca gatatcacga attaaaagca aaaatgcctt gcttagtgac agcactttct
    14041 gaattaaatc agccacgtta catgacacca ggtggaatct ttgatgcatg tgacaaagaa
    14101 gtgactgttt ggggaagagc agacttaaag gatgttgatg attctgacct tggattaaaa
    14161 ggatcaccaa caaagattgc aaaagcatct gataaagtag caaaaggagc tggtgagaaa
    14221 gtaaatcttg atccagcaga atccgtagca tacttgatcg gtaaattcaa agagaaacac
    14281 attatctaaa aaaataagga aaagtggtga ataagatgtc attagaagaa tataagggag
    14341 tatttgtctt tgcacagcag gtagataacg tattagacgg tgttgcattt gaattgcttg
    14401 gcaaaggtaa agatttagca aaagacttaa atacagaagt tacagcagta ttgatcggct
    14461 ctggcgtcaa aggattagca gatcagttag cagagtatgg tgcagaccgt gttatcgttg
    14521 tagacgatcc tgaattaaaa gaatacagaa cagagccata tgcacatgca ctggcatctg
    14581 taatcaatga gtacaaacca gagatcatgt tagttggtgc aacagctatc ggacgtgatc
    14641 ttggtcctac tgtatcagca agagttaaaa caggtcttac agcagactgt acttctcttg
    14701 aaatcggaga tttcccattg gttgctgctc caggaaaaga atctgagcag aaacacaatc
    14761 agttgttaat gactcgtcca gcatttggtg gtaacacaat cgctacaatc gcttgcccgg
    14821 ataaccgccc acagatggca accgttcgtc caggtgttat gcagaagatt gctccaatcg
    14881 ctggtgcaaa agcaaacgtt gttgaattca atccaggatt cacacctgac aacagatatg
    14941 ttgaaatcct caatgttgta aaagctgtaa aatctacagc aaatatcatg gaagctaaga
    15001 ttttggtatc tggtggacgt ggagtaggtt ccaaagagaa cttcaaactg ttagaggact
    15061 tagcagaagt tcttggcggt actgtaagct gctctcgtgc tgttgtagag aatggctggt
    15121 taccagtaga tcttcaggtt ggacagacag gtaaaacagt tcgtccacag atttactttg
    15181 caatcggtat ttctggagca atccagcacg tagcaggtat ggaagattct gatcttatca
    15241 ttgcaatcaa caaagatgaa gatgcaccga tcttcgatgt agctgattat ggtcttgttg
    15301 gagatttaaa taagatcgtt ccggcattga cagcagcttt aaagactgaa cttggtaaat
    15361 aaaccggagt ttaatttacc gtagtgtcgc agattttgta gcgcttttat aggttgtgaa
    15421 gggcagatat aagcgtcctc tcacaagtcg tgattttata ggtttatgaa aagaaaaaac
    15481 ggtacagacg aaatatgatg ttcctgttcg ccaggcattc cgataagtct ctaaagagtc
    15541 ttatctccat ggctcacgaa ggaaatcata tttgtctgta tcgtttttct ttcatttacg
    15601 ttgtgtgtcc agcgaagctg gaccacacta gccggtgtaa gtccggtcac ggtaatcgcc
    15661 agtgagccgt gtagctaaac tcggtgcgtt gcagtaatgc agggtactaa gcgagtggat
    15721 aaagtaacct cggtaagagg ggcgagcaat tatgcagacc gtaacataaa gtgaattctg
    15781 ccgtatcgtt agaaaggtct ctgaaaagag agcaaaggga agctgaacct tgggcgtatg
    15841 ggtgaaagcc atggaacgtg tgaagaaact ggaaagcagc acggaggaat ccctcggtat
    15901 ataggaaacg gtatgtatga aaagtgtggt tcggaactgg agagacccta cccatcaccg
    15961 aaaggtaaaa agaaagcgta taagcttggc gaaatcgtat ttctgatggg agggagtcgg
    16021 agaggaacat agtaccaata atgactgtgc aagaaaacgc agtctatggg aaggttcctt
    16081 gcttcattca tgtttgtaga gagggtaaga gtgagagaat gtcatgcaga ctaataactc
    16141 caaggaaaaa gttcgacaac ttcaaaacaa actatatctg acagccaaga aatgtgatag
    16201 ccgaagattt catgcacttt acgacaaggt atatcgtgat gatgtacttt ttgaagcatg
    16261 gaaacgggta aaagctaaca aaggttccag tggtgtagat ggtatcggaa tcgaagatat
    16321 tgaagagatg ggaattgaaa aatacctgtc agaaatcaaa tcggaactga tggatggaaa
    16381 gtataaacca tccccagtaa agcgagttat gataccaaaa ccagacggaa gtgaaagacc
    16441 tcttggaata ccaacagtca aggacagaat tgtgcagatg gctaccaaga tagcaataga
    16501 gccagtattc gaagctgact ttagagattg ttcctatgga ttccgaccga aaagaagtgc
    16561 caggcaagca ctggaagtgg taaggaaagc gtgtaacaac aagggctatt atgtagtaga
    16621 cgcagatatt gagaagttct ttgataacgt aaaccaagat aaactgatga aactggcaga
    16681 gcagagaata tcagaccgta ggatattgaa gctgataaga caatggttag tatcaggagt
    16741 attatacgga aatgtactga caatttccga actgggaaca agccaaggtg cagttatatc
    16801 tccgttattg gcaaacatct acttaaatac actggacaga ctgtgggaaa agtatggact
    16861 tactcacggt attcttgtaa ggtacgcaga tgatacagtc atcatttgca agaataagaa
    16921 aaatgcaaat cacgcactga acttattgca gtacatcatg gcaaaactgg atttaaagct
    16981 acacccagta aaaacaaaga ttgtcagcat gtgggacgga aaagagggat ttgactttct
    17041 tggaatgcac cacagaagaa tgacaacgga aacaagcaaa ggacaattgt ataaagaaac
    17101 ttatcagtac ccgagcagga aagccatgaa gaagatgaaa gcagaaatca aaaagaatgt
    17161 aaacggtcga agtctgttag ttgcaaagga agaggattta ataaagaatc taaatccgaa
    17221 aatcataggt tggaagaatt attattccac caaaacaaat gagacatgga tgcaggaatt
    17281 agactggtat attatctgca cctttacaag atggtataac aagaaacacc aaaggtgtaa
    17341 acatatgtca agagtgggat ttgttagaaa tagcatttac gaaaaaggat taaagaaaat
    17401 ggctagagca tgacgtaatg ctgtagaaag aagaatgtcg gaaagccgtg tgagggagaa
    17461 cctcatgcac ggtttgatga ggggcggatg aaattttcat ccgcctactc tacatggatg
    17521 acttgtgaga ggacgcttat acatgcccga tcaacgtcat gaatcgcacc acaaaatctg
    17581 caatttacgt tatggaactc acggttagtg gatgagtgcc tatattgggt tctgatgctc
    17641 gtaattcgga ttgacggatt ttcacaactg agatattgta tgctacacag tcttggctca
    17701 ataaaaaata gaactgattt gttttcagga ttttgggagc ggccggtcct tagaaagcag
    17761 acattgcgat ttcaaaagac aatgtaattg gattttgaaa gtgtataaaa attaaaaaca
    17821 aattgataaa cctttcacaa agtgctatgc tataaatgcg agcctgaacc gacctgatat
    17881 ggcggttaca ggcatgataa aatacatcat catagaaaag aggaagagac tatgaacaaa
    17941 aacaaattct ccacaaaata tcttgtggaa atggcattat tagttgccat cattttactc
    18001 atggctttta ccccgattgg ttacatcaaa acagcaggat tagaaattac cctgattgtt
    18061 gtaccggttg cggtaggagc tgtaacatta ggaccgacag caggtgcaat cttaggaggg
    18121 gtatttggaa taacaagctt tatccagtgc ttcggaatga gccagtttgg tgcattactg
    18181 cttggaatta acccattcct gacattcctt gtatgtgttc cgacacgtat tctgatggga
    18241 tggcttacag gacttattta tcatggattg cgaaaaacaa agattccgtc agcggcatcc
    18301 gttacgatcg ccagcctttg ctgcccatta ttgaatacaa cattctttat gggaacgctt
    18361 gtgacattat ttgcatccac catgcgtgaa tcttttggta tgggaaaggt acttccgttt
    18421 atctttgcat tcgtcggagt aaatggtgtt gtcgaggcaa ttgtatgttt cgttgtggga
    18481 actgcaattt ccatggcttt gaaaaaagca ttgcgttaca gctaaaacat tgcttaactt
    18541 aagaaatgcc gcttgcagga tgtggtgcgg atttttagat tgaattttat gaatccggct
    18601 atgaacggag tattgctccc tagcgcaggc ggcagagatt tctcaacttt tccagatcgt
    18661 cagaatccgg gtgtgacaaa gcacagtcaa aatttttgat caatgcatca aggttagccg
    18721 gatgctcagg attttctttc attttcatat agcgctcccg cacagactgc ggcatttttc
    18781 cctgacacat atattctccg ataatggtat tgcttggatc tatggactgt ctgacctgtc
    18841 cgaggatctt ttgaaaatat gcatcacttc caccaaaacc ggctgttccg aaaagaaaaa
    18901 tccgtcggtt ttttaaagtt gataacagag ttagtgtctc gttgtcagca tttcccttat
    18961 ctgtccaaaa tccgatatac aataattctg atgatggtac tggtgtcttg atcgcaccaa
    19021 aatactcaca gccctcttcg ggcagcgttt catggatcgc atcggcaagc ttctttgtat
    19081 tacctgttaa actgctgaat aaaatcgaat attgatctgt tttcatatgt tatcgtctcc
    19141 ttatgtaaaa gctgaatcac tggatgaacc tgcttcataa aagcgcaatt tggcagatcc
    19201 atcacatcat gatattatca caatcgtaaa tacttgtcta tttgattgaa gttttgtact
    19261 tcaaaaagaa cgttgtattt tctttgtatt attggaaaaa ttagatttat aggttataat
    19321 agaaatcaga caaattgtga ggtgacttta taaaatagga cagtagtcgt gcctcacaga
    19381 gacgaaggag ggcgtaaaaa tgccagaaaa cagcagttgc agcagtgcat ctacctgtag
    19441 cagggaaagc tgcgagggat gtccaagcaa agcaaagggc ggaagcggaa ttgccaaaga
    19501 gccaatgaac aaagcttcta atgtaaaaaa agtgattggt gttgtcagtg gtaaaggtgg
    19561 agttggaaaa tcatttgtga catcttccct tgcatgtgcc atgaacaagg ctggatataa
    19621 agtgggaatt atggatgctg atattacagg accgtccatt ccgaaaatgt tcggagtaca
    19681 tggacaggtt tacggtacag aggatggcat ggttccaatg gctgcagaga atgggatcaa
    19741 gatcatgtcc gtcaatctat tgttagacaa cgaagaagat ccggtgatct ggagaggacc
    19801 ggtgatcgcc ggtgttgtaa aacagttctg gaatgagaca gtatggggcg atattgatta
    19861 tttatttgta gatatgccgc cgggaaccgg tgatgttccg cttacggtat tccagtcact
    19921 tcctgtagat ggaatcgtcg ttgtgacatc accacaggaa ttggtacaga tgatcgtgaa
    19981 gaaggcttac aatatggcga atatgatgca tatcccggta cttggcgttg tggagaactt
    20041 cagttatctg gaatgtccgg actgtggtaa aaagatcaat gttttcggac agagccatgt
    20101 cgatgaagca gcacaagagc ttggaatccc ggtatttgga aaactgccgg tcgatccggc
    20161 ttacgcagag aaagcggatg aaggaaaatt ctttgagatc gacaatccat atttagcagc
    20221 cggtgttgaa actctgaaaa atttataaga tgtagaaaag gaaggtattg catgcgatat
    20281 cttccttttc tattgtatcc aatcaattcg gaaccggacc gccaagcgca aaggcaaaac
    20341 agaaaagcag aataaggcag agcggatatg caaacgcgag caatcctgca aacaaaaaag
    20401 catgtttgtg tgtggacttc ttatgactta accgtaaaaa ccatatgcca agaaaaaata
    20461 aaataatagg aaggcataca aatagaaaac cgaaggattg cattatgtca accagaaata
    20521 tcagtgcaat caacaggacg ataaagagtg tcacaagggc gatgcgttgc cgttctattt
    20581 ttctttcgta agatgcaaga tcaatcacgt tttgaaatgc atctgtggta tctggagcgg
    20641 aaacggttgt ttttggcaga cgctctgatt tcatcagttc aagcaggctg atatcaagaa
    20701 catctgctaa tggttcaaga agtttgatat caggaaagcc aacaccacgt tcccactttg
    20761 agacagcttt gtcggtcacg ttcaatttct gcgctaactg tgcctgtgtc aagccctttt
    20821 cttttcttaa ttcagtgata aaaattccta atttctgatt atccatagaa gttttccttt
    20881 cgatgtttcc tgatgtacta tattgtgaaa aaatgctcac ttttgccttc aggcaaatga
    20941 tacgatatgc aaaaccagct acttatatct tataaaaacc tcagaaaaat agcaatcgac
    21001 gaatcgtaga gccccctttt ttacgtctta tcaccgaaaa attacctctt acctcaaatc
    21061 tatttacagg atctggagca tcgaatatac taaactcagt taagaaatca aagagagctc
    21121 gcataaaata cattaacagt ttagacatat aaaaatctta agacgagaca aaaatcagca
    21181 attgaaaaat gacagaggag aaaaagagag cgcgaaaaag ttatgaaaat caaaattgaa
    21241 atcgatgagg gactcccaga ggacgaagta ctgatccggt gcaggggact gacggaacag
    21301 atttcggatg tgcagaaggc ggtgagcgaa gtgatcaaca cctcgcagaa attcgtcttt
    21361 tacagaggaa atacagagta ctacctgacc ttggatgaaa tcctgttctt tgaaacagac
    21421 agtgatggga tcaatgcaca tacgagagac aacatttacc agacaaaata caaactttac
    21481 gagcttgagg aacttcttcc gggaagtttt atgcggatat cgaaatctgc aatcgtgaat
    21541 accagccaca tttattcaat cagccggaac ctgacggcat caagtgtggt ggcatttgca
    21601 gacacacaca agcaggtgta tgtctcaaga tactattaca aaccattaat caataaatta
    21661 gaagaaaaga ggttacatca atgaaattaa gaaaaaacag tggaaaaatt ttatgggggt
    21721 tatttttcat ccttgcagca gtttatgtgg tagtcagcaa actctggatc atgcctgaga
    21781 tcagtgtgtt cagtgtttta ttgacggtat tctttatctg gctcttttta aatggtatcc
    21841 gcaacgtgaa tttctgggaa atcctgtttt ccatcgcatt tatatgtatc atatatgatg
    21901 actggcttgg aatcacagcc ctcacaccgt ggactgtttt gggcgcagcg ttactcggaa
    21961 gcattggact ttctttgatc ttcaaaaaaa agagcggaca cagcccttcc atttcttttg
    22021 agtttgacag tgacagcgac aacgaggatg gaaagtacat tggtgaaaat atcaaaattg
    22081 acaacaattt tggcacagcc atcaaatacg tgaattccga taacttctgt atggcggatg
    22141 tggataatag ctttggttcg cttaccgtat actttgataa tgccattatc cagtccggaa
    22201 gtgcaaaaat caaagttgac aatagctttg gcgaaaccaa tctttacatt ccgaaagaat
    22261 ggaaaacaga gaacaacctt ggtcaggcat tcggaagcgt caaaacacat ggcgtatgtg
    22321 agggaagcag taataacact ttgaaattaa aaggcgaaac aagctttggc gagattaaca
    22381 tatactatat ctagctaaga ctttcttaca agttattcac agtgtaaata aaagaaaaac
    22441 cgtacagaca aatatgattt cctttgtgag ctttgcgaac aggaacatca tatttcgtct
    22501 gtacggtttt tctttttcat taacctaaga tatcacttag ttaagttttg atttattcat
    22561 cgtgatcccc atagcttgta tcttcatgca ggttcggcat catatcaata ccacggtttg
    22621 aatccgcctc aacatccttt ccaaagtgat aatcattgcc aggtaaaatt gcatttaaga
    22681 gaataccggc aattgcagca attgcaaggg aagttaaagt aatatcagtt ccagcaacgg
    22741 taaaagtaag tccgttagaa aatccaagac cacatacgaa aataacaccg gcaatgatca
    22801 ggttgcgcga ttttgtcaag tctacgtggt tttctacaac gttacggaca ccgatcgcag
    22861 agatcatacc gtaaagcata aagctgacac ctccgatgat cgcagaaggc atagaaccga
    22921 tcacttctgc catctttgga ataaagctta aaataattgc atacaaagca gcgatacgga
    22981 taaccttcgg atcgtgtacc ttacttaact caagaacacc tgtgttctcg ccataagtag
    23041 tatttgcagg accaccgact aatgcggaga gggaagttgc aagaccgtca ccgatcaaag
    23101 tgcggtgaag tcccggatct tcgataaagt tttctccgac agttgcagag atggcagaca
    23161 tatcaccgat atgctccatc atggaagcaa gggcgatcgg agccataacc aaaatagcgg
    23221 agatattgaa tttacagata gaaaatttag gaacacctac ccatgcagca gatgcgatat
    23281 ttgtaaaatc aaggattgcg gaaccatctg catttgtcat tccaagtgca ttgaaaatca
    23341 gtgcggcagc ataggaaaca acaacaccca tcaggatcgg gatgatctta aacattcctt
    23401 ttccccagat attaaataca ataatggtag ccagtgcaat aaatgcaaga agccagtttg
    23461 tggaagcgtt gtttatggca gagccggaaa gacttaaacc gatacagata atgatcggac
    23521 ctgttacaac aggtggaagg aaacgcataa ctttttttac acctgcaaga cggatgataa
    23581 gagcaagtat tagataaagt aaacctgcta cgacgatacc gccacatgcg taggaaagtt
    23641 tgtctgcgtt ggacatatcg gcaaaaacgc cggtgtcaag atttgcgata gtcgcaaatc
    23701 cgcctaaaaa ggcgaaggat gaaccgagaa atgcaggaac cttgaatttg gaacacagat
    23761 ggaaaaataa tgttcccaca cctgcgcaga tcaaagtaac ctgaacgtga agtacatctt
    23821 caccaaagta gctgtttact aaaatcggta cgagaatggt tgcaccgaac atagcgaaca
    23881 tgtgctgtaa tcctaagatt aacatttttg ggacgccaag aacgctggcg tcacggattg
    23941 ctccgttctt ttcgttcata aaaaacttcc tccttaaaag taaaatgaaa atgataaggt
    24001 tttatgattt acctcaaatt aatttattat agcataggaa aacgggatgt tacaataaaa
    24061 aaatgcaatt gcttttactt gaagcgtgag aagggaacgt ggtacaatgg gtatcagcag
    24121 gattccgacg ggaaaacgtc agaacattgg attggcagat tgaggataag tctgtaaaac
    24181 aattcagaaa gaaaggattt accatggata ttattttgaa actctctgaa gaacttggta
    24241 tcagaaaaag tcaggcagag gcagcagtga aattgatcga tgaggggaat accattcctt
    24301 ttatcgccag atatcgtaag gaagtgaccg gttctttaaa tgatgaggtg ctccgtaatc
    24361 tatatgagcg tcttacctat ctccgaaatc ttgaagagcg taaggagact gttttaaaca
    24421 gcattgagga acagggaaaa ctgacagatg aattaaaggc acagattctt gcggctgaga
    24481 cgatggttgc agtggaggat ttataccgcc cttacaaacc aaagcgcaga acaagagcta
    24541 cgattgcaaa ggagagggga ctcgaacccc ttgccaatgt gatcactcta cagatgttaa
    24601 acacaccgct tgaggcagag gctgccaaat tcatcaatcc ggaaaaagaa gtcaattccg
    24661 cagaggatgc gattgccgga gcaaaagata ttatcgccga ggcggtttca gacgaggcgg
    24721 attaccgtac gagaatccgt gaccttacca tgaaaaaagg tcatgtgact tccacggcaa
    24781 aagatccgga ggcggaatct gtttatgaga tgtattatga gtttgatgag cctgtgaata
    24841 agctggctgg gcaccgcata cttgcgttaa accgcggtga gaatgagaag atccttaacg
    24901 tgaaagtgga ggcgccggag gaagatattt tacgttttct tgagcggaaa gtgatcacaa
    24961 gagacaatcc gaatacaaca cctgtattaa aagaagttgt ggcagatgct tacgaccgtc
    25021 tcattgcgcc tgcgatcgag cgtgagatca gaagcagtct cactgagatg gcagaggatg
    25081 gtgcgatccg tgtgtttggc aagaacttag agcagttatt gatgcagccg ccgatcgcag
    25141 gacaggttgt gcttggctgg gatccggcat tccgcaccgg atgtaaactc gcagtggtcg
    25201 atccgaccgg aaaagtgtta gatacgactg tcatttaccc gaccgcacca cagaacaaag
    25261 tggaagaggc aaagacggta ttaaaaaaac ttatttccaa atatcatatc acattgatat
    25321 cacttggaaa tggaactgcg tcaagggaat ctgagcaggt ga
//
