LOCUS       c00066_NZ_FNHQ..       14657 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FNHQ01000033.1 Megasphaera paucivorans strain DSM 16981, whole
            genome shotgun sequence.
ACCESSION   NZ_FNHQ01000033
VERSION     NZ_FNHQ01000033
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:27:33
            Original ID  :: NZ_FNHQ01000033.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14657
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..330
                     /locus_tag="ctg66_1"
                     /transl_table=11
                     /translation="RGIRLSGPALGRPKKDAVRDKRLEYKDNCDRVEVERAFSLAKRRF
                     GLSQIRTYLKETTQSVIALSILALNLRKLQAIQCTPILFYLQLLLWKVKRALKWLPCQK
                     VVFAQ"
     protocluster    1..14657
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1604:4657]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1605..4657
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14657
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14657
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             270..1346
                     /locus_tag="ctg66_2"
                     /transl_table=11
                     /translation="VESKTGLKMAAVSKSGFCAVDIIYDITTDFQDKKLLYDTYKELNL
                     DVADIHISFVPPYTFDETFITKTVQYHYNQYRFNKNQTCLTIFYDVYKRLYLSNIPVVY
                     LSPTIYDICNDIRKAQADFLLQISRESQLIIIDVVIDERDNYSPLNTNEYQLTFENINV
                     MKQVYLFAKKIQASVISVTETEFLLFSTRAIVENQTDKFHKFSLFDDIQKHTVSTVSVG
                     IGFGKTAMEAKYHARLGVKRAISGGGNQLFLVYDLETIRGPIGNEKEYDLNISNSFLSI
                     SQQTGVSSVTLCKLHNMIVAQGKNEFTTAEIADALHVTPRTIDRIVLKLMQFDYCFESG
                     KKYQQKNGRPSRILKFKI"
     CDS             complement(1298..1402)
                     /locus_tag="ctg66_3"
                     /transl_table=11
                     /translation="MVFCCISMVKYDGCFCHVFYILNFKMRLGRPFFC"
     CDS             1605..3857
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_4"
                     /sec_met_domain="Gly_radical (E-value: 8.8e-41, bitscore:
                     129.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.5e-262, bitscore:
                     863.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHFQEWNGFNGRLWKEECNVRDFIQHNYRIYDGNADFLEGPTEG
                     TSKLWAKLQELQKAERKNGGVLKEETEIVSSLTAYGPGYIDDQLKHWEQIVGLQTDEPL
                     KRAFMPYGGIKMAEEALEMYGYTLNPSLHKIFTEYHKTHNQAVFDAYTEEMQTARHTHI
                     VTGLPDTYGRGRIVGDYRRIALYGIDQLIVWKQEDKTNCGDGVMTDDVIRQREELSEQI
                     RALEDMKKMAAVYGFDISHPATTAKEAVQWLYFGYLAAIKTQNGAAMSVGRISTFLDIY
                     IDRDLQRGILSESTAQELIDHLTLKLRMVKFARIKSYNELFSGDPVWATLEVAGIGMDG
                     RSMVTKTDFRFLHTLENMGPAPEPNLTVLYSSALSNAFKRYAASISVKTSSIQYENDDV
                     MKPVWGDDYSICCCVSATQTGKEIQFFGARANLAKALLYAINGGIDEKFGIQAGPELAP
                     ITSEYLDYDEVLRKYKLMLDWLAGLYVNVLNTIHYMHDKYYYEAAEMALIDTNVRRTFA
                     TGIAGFSHVIDSLSAIKYAKVRVIRNDKGLAEDFAIEGDFPKYGNDDDRADDIGIWLLH
                     EFITDVRKRHTYRNSEPTTSILTITSNVVYGRFTGNLPDGRRAWTPFAPGANPSYGAEE
                     NGMLASLNSVAKLPYIWSLDGISNTQSMNPESLGHTDTERTANLVHVLDGYFDQGAHHL
                     NVNIFEKEMLIDAMEHPEKPEYANLTIRVSGYAVKFIALTREQQLDVISRTFHNKL"
     CDS             3972..4148
                     /locus_tag="ctg66_5"
                     /transl_table=11
                     /translation="MAPVCVLLYSCRDALCAAGIVIIPKPGILTQVQEGHRKMYCSRHY
                     AISHIGRITAVSR"
     CDS             4145..4657
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_6"
                     /sec_met_domain="Radical_SAM (E-value: 3.2e-17, bitscore:
                     54.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSGGEALLQLDFVTELFRLSKEQGIHTALDTSGNPFTRNQPFWEK
                     FQKLCEFTDLFILDIKEMDEEKHKKLTGQRNVNILELASTLSDFGKPMWIRHVLVPGLT
                     DDEEGLHRMAHFIKTLKTVERTEILPYHTLGVPKWEQLGIPYTLKNMQSPTAEQIRRAE
                     IILGIDH"
     CDS             complement(4779..5396)
                     /locus_tag="ctg66_7"
                     /transl_table=11
                     /translation="VVQKEDDDMNFISADIRKKLEPILAKFEHKVILKAWIDDSEFSME
                     LKNFAKEFCSLTANVLYEEGIIEGAPGLEIIREDETSSGIIFHSVPGGHEFNSFVLALY
                     NVGGPGQDLDPAVEKKLEHIQKTVHIQVVVSLSCTMCPEVVIATQRLAAASPKITAEMY
                     DVQHFPALRKKYNIMSVPCMIVNDTEVYFGKKNISEIIDLLL"
     CDS             complement(5369..6403)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_8"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.1e-45, bitscore:
                     145.0, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNMYDAVIVGGGPAGLSAAIYLGRAKYKVLVVEKEKIGGQIAIT
                     SDVANYPGIKQISGAELTDEMYAQAIKFGVEFVDAEVKELTLEQQIKKMDTTKGSYQAL
                     SVILATGANPRKIGFIGEEKFQGHGVSYCATCDGEFFSGRDVFVIGGGFAAVEESIFLT
                     KYAKSVTILVRKNSFSCAGTVVDELKKYPKITVKFNTELVLAGGNQTISYVAFKNNKTG
                     ETWRYDVAGQGGLGVFVFAGYIPNTALFADTINLNQQGYVITDANQKTNLDGVYAAGDV
                     CIKNLRQIVTAVSDGAVAATALDTYISTMHDKLNLSGVSQIKKVENKSKKRMKIKWYKK
                     RMMI"
     CDS             complement(6427..6990)
                     /locus_tag="ctg66_9"
                     /transl_table=11
                     /translation="MSLINKEVADFTVQAYQNGEFKEITKKDILGKWNVFFFYPADFTF
                     VCPTELEDLANSYDKFKAIHCEVYSVSCDTHFVHKAWHDSSKSIEKVTYPMIGDPVAIL
                     ARDFDVYIESAGLAERGTFVVNPEGKIVAYEVNAGNVGRNADELLRKVEASQFVAEHGD
                     QVCPAKWQPGAETLKPSFDLVGAI"
     CDS             complement(7173..8381)
                     /locus_tag="ctg66_10"
                     /transl_table=11
                     /translation="MTEKLYEQDSLARECKAVVTSCVFDGEKYNIVLDRTVLFPEGGGQ
                     LSDTGRIEGDGKIVYVLHGTDKEGTISYCCDALLSPGTEVTVYVDWQRRLDYMQQHCGE
                     HILSYSFWKLFGVHNIGFHMSERMVTIDLDQEITREQAVQAEDFANEEIWQNKKIHVLY
                     ATPSEAAKLAMRKKNEKIKGMVHIVAIDDGDVCTCCGTHPPYTGMIGIIKIMKMIRHRG
                     GMRIEFLCGRWALENIRQDVQYIEEASNILSTKEKLVCEGIRRLQEEVRMLREDVRQQM
                     EVLQRQEMDEIWKKCVNDEQGNVVFTIMKDSYTPKSAKMLLQKLIAVDHAVVAIVYCQE
                     NRIYYMFGSGVEANSDCRAYIKMANTLFNGKGGGSSVLCQGSAPAFSQWKQQAEKLFEC
                     IRK"
     CDS             complement(8795..9619)
                     /locus_tag="ctg66_11"
                     /transl_table=11
                     /translation="MKFKKIGILLFTVIAGATFLMGCGGDDTGSAKKEITYSKSQGPYS
                     ELFEKGIKPILEKKGYKVTGKDMSDLLQADVALNEGEVDFNVEQHTAYMENFNKKQNGH
                     LVALTPIPTVPAGIYAGSKSSLDQISDGAKVAVPNDAANTARCYALLQKVGWIKLNPEK
                     DLSTVTQQDIIENPHHIQFTEMKSLNIPAVRGDFDFIVITGSIVYNANIDPSTALATED
                     ILPHLLLQLVVLDKNKDAQWAKDIVSAYHSDEFKKYMGEHNNGLWYIPKDNQ"
     CDS             complement(9664..10323)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 62.5; E-value: 1.4e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg66_12"
                     /sec_met_domain="BPD_transp_1 (E-value: 6.2e-20, bitscore:
                     62.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIELGVPNSRLILAAEQTIYMVFVSLGIGTLIAVLLSVVLVLTNP
                     GGILKNKYIYVVVNTVVNVIRSIPFIILMVFILPLTKMIVGTRIGTTAALVPLVVFIAP
                     YLTRLFENSILEVNKGIIEAAQAMGASYFEIVRYFLLPEARGSLILSVTTGTIGLIGAT
                     AMAGAIGAGGVGNLALTYGYERLNFPLMLFTVVILIVFVQSIQTVGNYFSTKVRKH"
     CDS             complement(10320..11342)
                     /locus_tag="ctg66_13"
                     /transl_table=11
                     /translation="MINFVNISKTFTVKRQKIKALQHVSLQISDGDIFGVIGFSGAGKS
                     TLLRMVNALEIPTEGRMEVDGRDINALDFSELRKVRKKIGMIFQEFNLLESKSVYDNVA
                     IPLILNHVDKKLIQKRVTELLSFVELSDKALAYPSQLSGGQKQRIGIARALANNPSILL
                     CDEATSALDPETTESILQLLKRINKKLNITILIVTHEIHVIQSICNRVAVMEHGSVVET
                     GTVLEVFSNPQQNMTKRFVQTVIPDEIPPSIVETLHDDVRNYRLLKIRFLGNNAKRNIV
                     YYINTHYKVETNILFASVNELQQTVLGIFIVQVIGDDSEINQVISYIERNKIQWQEVVL
                     "
     CDS             complement(11335..12498)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_14"
                     /sec_met_domain="Peptidase_M20 (E-value: 4.2e-35, bitscore:
                     112.1, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEQLIQRKITEEFYWFHEHPELSYKEVETTKRLRVNLQSAGIKI
                     LQIPLKTGLVAEIGTGSAPIVALRCDIDALPVQEKTELPYRSKIDGHMHACGHDFHAAA
                     ILGAAYILKQHEQEINGTIRLIFQPAEEAPGGALKIIQSGALQDIQVIFGIHSSPLFPI
                     GDIAIREGAVTAAVDRFSITFTGKGTHAAHPQEGFDPIVAAAAFISSVQSIISRNVNPF
                     DANLVSITHFESGSNWNIIPEQAFLEGTVRTLTADDRTYIQKRILDLAKYTAKSYNERA
                     DVQWFSGPPATANDENWVAFAKEEAEKQQLKVRVSPFSLGGEDFAFYQEKIKGVFIQMG
                     TGTSYPNHNPHFQVDPIALYPTSQYTSRLAVQAIEKIRQVSGSGKND"
     CDS             complement(12945..13709)
                     /locus_tag="ctg66_15"
                     /transl_table=11
                     /translation="MAIIEISDLAFSAFNEIEMEKLPEDYGIEFFYEFGSDSYWDVVLH
                     RMRADKKTLSIHGPCVTVNLADPNDTAYLERYRKTFLYAKKTGAKYVVVHTNEQWSGDM
                     EFCRQLVLERLRRIELLANELDGAKMGIENVGLKQNNLFDEEAYVALFEEFQTAGAIID
                     VGHAHINNWDTCRVIRELNRRISALHLQDNNGKIDEHLPLFAGTIAWRSLMEIIKQYAS
                     QAAFVFEYADGNYKNAADMIKELDVVRKKLRI"
ORIGIN
        1 agaggcattc ggttgtcggg acctgcctta ggacggccca agaaagatgc tgttagagac
       61 aaacgattag aatacaaaga caattgcgat cgcgtggaag tagaacgagc tttcagttta
      121 gcgaaacgtc ggtttggcct tagccaaatc agaacatatc tgaaagaaac gacacagagt
      181 gtgatagcgc tgtctatttt ggcactgaac ctgagaaaac tccaggctat tcagtgtacg
      241 ccaattttat tttacctaca gttactactg tggaaagtaa aacgggcctt aaaatggctg
      301 ccgtgtcaaa aagtggtttt tgcgcagtag acattattta tgacattaca acagattttc
      361 aagataaaaa attactatat gacacctaca aagaactcaa ccttgatgtc gcggatattc
      421 atatatcgtt tgtaccccca tatacatttg atgagacttt tatcaccaaa acggttcaat
      481 atcactacaa ccaatatcgt ttcaataaaa atcaaacttg cctaactatc ttttatgacg
      541 tgtataaacg actgtattta tcaaacattc ctgttgtata tttatctccg actatttatg
      601 atatatgcaa tgatatccga aaagcacagg ctgattttct tttgcaaatc agccgggaaa
      661 gccaattgat cattatcgat gtcgtcattg atgaacgaga caactattct cctttaaata
      721 caaatgaata tcaacttacc tttgaaaata ttaatgtaat gaaacaagtt tatctctttg
      781 caaaaaaaat acaggcgtcc gttatttccg taacagaaac agaatttctc ttattttcca
      841 cacgggcgat tgtagaaaat caaacagata aatttcataa attttcatta tttgatgata
      901 tacaaaagca tacagtcagt accgtcagtg ttggcattgg attcggaaaa acagctatgg
      961 aggcaaaata tcatgccaga ttgggagtaa aacgtgccat cagcggcggc ggaaatcaac
     1021 tttttttagt ttatgattta gaaacaatca gaggtcctat cggcaacgaa aaagaatatg
     1081 atttaaatat atcaaattct tttttatcta tctctcaaca aacaggggta agttccgtta
     1141 cattatgtaa actccataat atgattgttg cgcagggaaa aaatgaattc accaccgctg
     1201 aaattgcaga tgcactgcat gtaactcccc gaacaattga taggatcgta ttaaaactca
     1261 tgcaatttga ttattgtttt gaatccggaa aaaaatatca gcaaaaaaac gggcggccca
     1321 gtcgcatttt aaaattcaaa atataaaaca cgtgacaaaa acaaccgtca tatttcacca
     1381 tggagatgca gcaaaaaacc atttctgcat cctctttttg tcatattgac aaattcctct
     1441 tccaacggtt ataatttcat tagaattatg tgactgacgg aagtggagca accacatgaa
     1501 gcataatttc tgataagccg accgtctggg caaagggcca gatttgtcgg tcttttttta
     1561 tcatctattt aaaataaatg gttgtataag aaaggggcat gcacatgctg cattttcagg
     1621 aatggaacgg atttaacggc aggctatgga aagaagaatg taatgtacgg gattttattc
     1681 aacacaatta tcgaatttat gatggaaatg ccgattttct ggaagggcct acagaaggaa
     1741 caagcaaact ctgggctaaa ctgcaggaat tgcagaaagc tgaacgaaaa aacggcggtg
     1801 tcttgaaaga agaaacagaa atcgtttcca gtttaactgc ttatggtccc ggttatattg
     1861 atgatcaatt gaaacactgg gaacaaattg tcggtctgca gacagatgaa ccgctaaaac
     1921 gtgcttttat gccttacggt ggtataaaaa tggcagaaga agcattggaa atgtatggct
     1981 atacactgaa tccatcactt cacaaaattt ttacagaata tcacaaaaca cataaccaag
     2041 ctgttttcga tgcctataca gaggaaatgc aaacagcgcg tcatacacat attgtaaccg
     2101 gtcttccaga tacatacggg cgcggccgta ttgtaggcga ttaccgccgt atagcacttt
     2161 acggaataga ccaattaatt gtgtggaaac aagaagataa aacaaattgc ggtgacggag
     2221 taatgacgga cgatgtaatt cgacaacgtg aagaactttc cgaacaaatc cgtgcacttg
     2281 aagatatgaa aaagatggca gctgtttatg gcttcgacat ttctcatcct gcaactacgg
     2341 caaaagaagc ggtgcagtgg ttgtattttg gctacttagc tgccatcaaa acacaaaacg
     2401 gtgctgctat gtctgttggt cgtatttcga catttttaga catttatatt gatcgggatc
     2461 ttcaacgcgg catactctca gaaagtacag cacaagaact tattgatcac ctgacgttaa
     2521 agctgcgcat ggtaaagttt gcacgtataa agtcctataa tgaacttttc tccggtgatc
     2581 ccgtttgggc tacattggaa gtggcaggaa tcggtatgga tggtcgttct atggtaacga
     2641 aaacagattt tcgttttctc cacacattag aaaacatggg tcctgctcca gaaccaaatt
     2701 tgacagttct ctattcatcc gctctttcta atgcatttaa gcggtacgcg gccagtattt
     2761 ctgtaaaaac cagctccatt cagtatgaaa atgatgatgt catgaaaccc gtatggggtg
     2821 atgattattc tatttgctgc tgtgtttcag ctacacaaac gggcaaggaa attcagtttt
     2881 tcggagctcg ggcaaatctg gccaaagcac tgctgtatgc cattaacggt ggtatagatg
     2941 aaaaatttgg aatacaagcc ggaccggaat tagcaccaat tacatcagaa tatcttgatt
     3001 atgatgaagt gttgagaaaa tacaaactca tgttggattg gctggccggc ttatatgtca
     3061 atgtactgaa caccattcac tatatgcatg acaaatacta ttatgaagcc gcagaaatgg
     3121 cgttgatcga tacaaatgta cgccgaacat ttgcaacagg tattgcaggt ttttctcatg
     3181 ttattgactc tttatcggca atcaagtatg ccaaggttcg cgttatccgt aatgataagg
     3241 gtctggcaga agactttgcc atagaaggcg atttcccgaa atatggaaat gatgatgacc
     3301 gagctgacga tatcggtatc tggctcctgc acgagtttat tacagatgtc cgcaagagac
     3361 atacctatcg caattctgaa cctacaacat ctatcctgac cataacatct aacgtcgtat
     3421 atggacgttt tacaggaaat cttcctgatg gcagacgcgc ttggactcct tttgctcccg
     3481 gagcaaatcc cagctatggg gcggaagaaa atggaatgct ggcttctttg aattccgtcg
     3541 ccaaacttcc ttatatttgg tcgttggatg gcatttccaa tacacaatcc atgaatcccg
     3601 agtccttggg tcataccgat actgaacgaa ccgctaatct cgtccatgtc ttggatggct
     3661 actttgacca gggggcacac cacctaaatg tcaacatctt tgaaaaagaa atgctgatcg
     3721 acgcgatgga acaccctgaa aaaccagaat atgctaattt aacaatccgt gtatcaggct
     3781 atgctgtcaa atttatcgcg cttacccggg aacagcaact agacgttatt tcccgtacat
     3841 ttcataataa actctaacta aaaacacagc cctgaatact ttcagggctg tgccgtttgg
     3901 aataagaggt gaaaaaatgg ctgaacaact tacaggactc attaattcga cagaatcctt
     3961 cggagccgtt gatggccccg gtgtgcgttt tattgtattc atgcagggat gctctatgcg
     4021 ctgccggtat tgtcataatc ccgaaacctg gaatacttac acaggtacaa gaaggacacc
     4081 gcaagatgta ttgcagcagg cattacgcta taagtcatat tggaagaatc acggcggtat
     4141 cacggtgagc ggtggtgaag ccttgctgca attagatttt gtgacagaac tctttcgctt
     4201 atcaaaagaa caaggtatac ataccgcatt agatacctcg ggaaacccct ttacacgaaa
     4261 tcaacctttt tgggagaaat ttcaaaaact ttgcgaattt accgatttat ttatactgga
     4321 tatcaaagaa atggatgaag aaaaacataa aaaattgaca ggacaacgta atgtcaatat
     4381 tctcgaactg gcaagcacat tatcagattt tggtaaacct atgtggattc gccatgttct
     4441 tgtacccgga ttgactgatg atgaagaggg gctgcatcgc atggcccatt ttataaaaac
     4501 cttaaaaacg gtagaacgaa cagagattct gccgtatcac acattaggag ttcctaagtg
     4561 ggaacagttg ggtattccct atacattaaa aaatatgcaa tctcctacgg cagaacaaat
     4621 ccggcgggca gaaataatat taggtataga tcattaatat atgccgtata caattcctta
     4681 tgtttaccgc tcatgtcaaa aaaacatata ccatagtaac aatagaacgt cctcctatac
     4741 aacatgtgta caggaggacg ttctattgtt actatgcctt acaacagcaa atctataatt
     4801 tcagaaatat tctttttgcc aaaataaacc tctgtatcgt ttacaatcat acaaggcaca
     4861 ctcataatat tatatttctt tcttaaagca ggaaaatgct gtacatcata catttctgct
     4921 gtaatcttgg gagatgcggc cgccaggcgc tgcgttgcga tgacaacctc aggacacatc
     4981 gtacatgaca gagataccac aacttgaata tgtaccgttt tttgtatgtg ttctaatttt
     5041 ttttccactg cgggatccag atcttgtcct ggaccgccta cattatataa tgcaagaaca
     5101 aaggaattga attcatgtcc tcccggtaca ctgtgaaaaa taattccgct gctagtttca
     5161 tcttcacgaa taatttccaa accgggtgct ccctcaatta taccttcttc atataataca
     5221 tttgcagtta aactgcaaaa ttccttagca aagtttttca attccattga aaattcgcta
     5281 tcatcaatcc atgctttgag aattacttta tgttcaaatt tagctaaaat cggttcaagc
     5341 ttttttctaa tatctgctga aataaaattc atatcatcat cctctttttg taccacttta
     5401 tcttcatcct tttttttgat ttattttcca cttttttaat ttgactgacc ccagataaat
     5461 taagtttgtc atgcatcgtt gaaatatatg tatccaaagc cgttgcagca acagctccat
     5521 cagatacggc ggttacaatc tggcgtaaat ttttaataca cacatccccg gctgcatata
     5581 ccccatcaag attagttttc tgattcgcat cggtaatcac gtatccttgc tgatttaaat
     5641 ttattgtatc tgcaaaaagt gctgtattag gaatgtatcc ggcaaataca aagacaccca
     5701 aaccaccctg tccagccaca tcataccgcc acgtttctcc tgtcttatta tttttgaacg
     5761 caacatagga tattgtctgg tttccacccg ctagaactag ttctgtgttg aattttacgg
     5821 taatttttgg atattttttt aattcatcaa caaccgtccc tgcacatgaa aagctatttt
     5881 tacgcacaag aatagttaca cttttagcat attttgtcaa aaaaatactt tcttccacag
     5941 cagcaaaacc cccgccgata acaaaaacat ccctccctga aaaaaattcg ccatcacagg
     6001 ttgcacaata ggaaacacca tgtccttgaa atttttcttc tccaataaat cctatttttc
     6061 gtggattggc acctgttgcc aatatgacag atagcgcttg atagcttcct ttggtggtat
     6121 ccattttctt tatttgctgc tccagcgtca actccttcac ctctgcatca acaaattcta
     6181 caccaaattt tattgcctgg gcatacattt catccgttaa ttctgcacca cttatctgtt
     6241 ttattcctgg atagttggca acatctgaag taatagcaat ctgtccaccg attttttctt
     6301 tttccacaac aagaacttta tactttgctc tgcctaaata tatggcggca gagagccctg
     6361 ccgggcctcc gccgacaatt acggcatcat acatatttct catatgcatc gcctcactgt
     6421 tatttcttaa atagcaccaa ctaaatcaaa acttggcttc aatgtttctg caccaggctg
     6481 ccattttgcc gggcatactt gatctccatg ttctgccaca aattgagaag cttctacttt
     6541 gcggagcaac tcatcggcat tacgtccaac gttgccggca tttacttcat atgccactat
     6601 tttcccttcc ggattaacaa caaaagttcc tcgttcggct aaccctgcac tttcaatata
     6661 cacatcaaaa tcacgcgcca atatagccac gggatcacct atcatcggat acgtaacctt
     6721 ttcaatagat tttgaagaat catgccaggc tttatgtaca aaatgagtgt cacacgatac
     6781 actatatact tcacaatgaa ttgctttaaa tttatcatat gaattagcca aatcttctaa
     6841 ttccgtcggg catacaaaag taaagtccgc tggataaaag aaaaatacat tccactttcc
     6901 aagaatatcc ttttttgtta tttctttgaa ttcaccattt tgatatgcct gcacagtaaa
     6961 gtcagctact tctttattaa ttaaagacat aatcgtcact cctttgttaa ttattattaa
     7021 ctaatatata ttatcagttg atgattataa aataccactt ttattcttat aagtcaataa
     7081 taattctcaa tatcttccag ccgtatatat acccataata aattcaaaaa atcgtataaa
     7141 cctgtatttc acaaaacccg cccatttatt tcttattttc taatacattc aaaaagcttt
     7201 tctgcttgct gtttccattg agaaaatgct ggagcagatc cttggcataa aacagaactg
     7261 ccgccgcctt taccgttaaa aagtgtatta gccattttaa tatacgcacg gcaatctgag
     7321 tttgcttcta ccccactgcc aaacatataa taaattcgat tttcctgaca atacacaatt
     7381 gccactaccg catgatcaac agcaattaat ttttgaagaa gcatttttgc cgacttagga
     7441 gtataggaat ccttcataat agtaaatacc acattgcctt gttcatcatt tacgcacttc
     7501 ttccatatct catccatttc ctgccgctga agaacttcca tctgctgacg cacatcttca
     7561 cgaagcatac gcacttcttc ctgcaatcta cgaatcccct cgcagaccaa tttttctttt
     7621 gttgataaga tattacttgc ttcttcaata tactgtacat cctgacgaat gttttccagc
     7681 gcccatcgtc cgcacaaaaa ttcaatacgc ataccgccac gatgtcgtat cattttcatt
     7741 attttaataa ttccgatcat ccctgtatag ggcggatggg ttccacagca agtacacaca
     7801 tctccatcat caatggcaac gatgtgaacc attcccttta ttttttcatt ttttttccgc
     7861 atagccaact tagctgcttc cgagggagtt gcatataaca catgaatttt cttattctgc
     7921 caaatttcct cattcgcaaa atcttccgcc tgtacagcct gctctcgcgt aatttcctga
     7981 tccaaatcaa ttgtaaccat tcgttcactc atatgaaatc caatgttatg cacaccaaac
     8041 agcttccaga acgagtatga taaaatatgt tccccacaat gctgctgcat gtaatccagt
     8101 cgtcgctgcc aatctacata tacagtgact tccgttcctg gtgacagcag ggcatcacaa
     8161 caataagaaa tggtaccttc tttgtctgtc ccgtgaagga cataaacgat ttttccatct
     8221 ccttctattc ttcctgtatc actcaattgc ccgccgcctt caggaaataa aaccgttcga
     8281 tccaatacaa tattgtattt ttctccatca aaaacacacg atgtaacaac tgccttacat
     8341 tcccgggcca aagaatcttg ctcatataat ttttctgtca tcatattacc tcacaaaaat
     8401 aacatagtat aaaccaacct gattaacgta aaagtacata tcgatacatt gacacctgaa
     8461 ttcctgcttt aaatactgct ttttcatcac aataggaata ctagctcaca taattaccgc
     8521 tctttgtttt atcaatcagc aatctaacca gcaacagttt cattcccagt gcaatatcga
     8581 ttgcaatatg attataccta tctcctaaaa aaacagcaca caagaatatt cccccttcac
     8641 ctccttgtgt gccgcccttt gtattttatt ttactatagt atacagactc aaattatatt
     8701 atgcaagaaa acaatttaat atatatgata cttaaaatta tcattttttc tatgcatatg
     8761 actgctgaag ttcttggtat cggtaaaacg ttatttactg gttatcttta ggaatatacc
     8821 acaatccatt gttgtgttcc cccatatact tcttgaattc atcagagtga tatgcagaaa
     8881 ctatatcctt agcccattgt gcatctttat tcttatccaa tacgacaagc tgtaaaagaa
     8941 gatggggtaa aatatcttcc gtagcgagtg ccgtcgaggg atcaatgttt gcattataaa
     9001 caatagatcc tgtaatgaca ataaaatcaa agtcaccacg aacggctgga atattcaaag
     9061 acttcatttc tgtaaattga atatgatgcg gattttctat aatatcttgt tgagttactg
     9121 ttgacaaatc cttttctgga ttgagtttaa tccaacctac cttctgcaac aatgcatagc
     9181 agcgagctgt attggctgcg tcattaggaa cggccacttt agcaccatca ctaatttgat
     9241 caaggcttga cttagaacct gcataaattc ctgccggcac ggttggtatg ggggttaatg
     9301 ccactaagtg accattttgt tttttattaa aattttccat atatgccgta tgttgctcta
     9361 cattaaaatc aacttctcct tcattcaacg ctacatcagc ctgcaaaaga tcagacatat
     9421 cttttcctgt tactttatat cctttctttt ccaaaatagg ttttatacct ttttcaaaca
     9481 attcagaata tggcccttga gacttactgt atgtaatttc ttttttcgca ctgccagtat
     9541 cgtctccgcc gcaccccatc aaaaaagttg ctcccgcaat aactgtaaat aaaagaattc
     9601 ctattttttt aaatttcata ttttttccct ctttctacat aaattatatt tttcaaaaaa
     9661 catttaatgc ttacgtacct tagtcgaaaa ataattgcca acagtttgaa tgctttgtac
     9721 aaaaacaata agaataacaa cagtaaataa catcaatgga aagttaagtc tttcatatcc
     9781 atacgtcaat gccagattcc caacaccacc tgcacctata gccccagcca tagcagttgc
     9841 tccaataagg cctatagtcc cagttgtcac cgaaagaatc aatgacccgc gcgcttctgg
     9901 caataaaaaa tacctgacga tttcaaaata tgaagccccc attgcttgtg ctgcttcaat
     9961 aatccccttg ttcacctcca aaatagaatt ttcaaataaa cgagttaaat atggcgcaat
    10021 aaaaacaacc aatggaacta atgccgctgt ggtgcctata cgtgtaccaa caatcatttt
    10081 tgtaagaggt aaaataaaga ccatcaaaat aataaaagga atactgcgga taacgttgac
    10141 cactgtatta acaacaacat atatgtattt attttttaaa ataccacctg gattcgtcaa
    10201 taccagtaca acagataaaa gtacagcaat aagggttcca atacccaatg aaacaaaaac
    10261 catataaata gtctgttctg ccgctaaaat cagtctggaa ttaggaacac ccaactctat
    10321 catagtacca cctcctgcca ttgaatctta tttctttcaa tgtatgaaat aacttgattg
    10381 atttcactat catctccgat gacctgcaca ataaaaatac ctaacacagt ttgctgcaat
    10441 tcattgactg atgcaaataa aatattcgtt tctactttat agtgagtgtt gatatagtat
    10501 actatgtttc tttttgcatt atttccaaga aaacgtattt ttaaaagcct gtaatttcgt
    10561 acgtcatcat gtaatgtctc aacaatactg gggggaattt cgtcaggaat aacagtctgt
    10621 acaaaccgtt ttgtcatatt ctgctgcgga ttactaaata cttcaagaac cgtacccgtc
    10681 tccaccacgc tgccatgttc cattacggca acacgattac aaatactttg gatgacatga
    10741 atttcatgcg taacaataag aattgtaata ttcaactttt tattgatgcg tttcaatagt
    10801 tgtaaaattg attccgttgt ttctggatcc aaagcactcg tagcttcatc acaaagaagg
    10861 atagatggat tatttgccaa tgctctcgca atgccaatac gctgcttctg tcctcctgat
    10921 aattgagacg gatacgccaa tgctttatct gacaattcaa cgaaagatag taattccgtt
    10981 acccgttttt gtattaattt tttatctaca tgattcaaaa tcaacggaat cgctacatta
    11041 tcataaacag acttggattc taataaatta aattcttgga atatcatccc gattttctta
    11101 cgaacttttc gcaactctga aaaatcaagc gcattgatat cacgcccatc aacttccatt
    11161 cgaccttctg ttggaatttc caaggcattt accatacgca acaacgttga cttaccggca
    11221 ccgctaaaac caataacgcc aaatatatca ccgtcactga tttgtaaaga cacatgttgt
    11281 aatgctttta ttttttgtct ttttacagta aaagttttac tgatattaac aaagttaatc
    11341 attttttcca ctccctgata cctgtcttat tttttcaatt gcttgcacgg ctaatctcga
    11401 cgtatattgt gaagtcgggt atagtgcgat gggatcgact tgaaagtgag gattgtgatt
    11461 gggataagat gttccagtac ccatttgaat aaacacgcct tttatctttt cttggtaaaa
    11521 agcaaaatcc tctccgccta gagaaaatgg tgaaactcga acttttagct gctgtttttc
    11581 tgcttcttct ttggcaaacg caacccaatt ttcatcattt gctgttgctg gcggtccact
    11641 aaaccattga acatctgctc tttcattata agatttagct gtatatttgg ctaaatcaag
    11701 aattcgtttt tgtatatacg tacgatcatc cgcagttaac gtacgtacag tcccctccaa
    11761 aaaagcttgc tctggaataa tattccaatt actgccactt tcaaagtgag tgatactgac
    11821 taaattagcg tcgaaaggat ttacattacg gctaataata gattgcacag aactaataaa
    11881 agcagccgct gcaacaatcg gatcaaatcc ttcttgtgga tgagctgcat gcgttccttt
    11941 cccagtaaaa gttatactaa aacgatccac agcagccgtt acagcgcctt ctcggatagc
    12001 aatatctcct ataggaaata atggagaact atgaatacca aaaatgacct gtatatcttg
    12061 taatgccccc gactgtataa tttttaatgc tcctcccgga gcttcttctg ctggttgaaa
    12121 aataagtctg atcgttccat ttatttcttg ttcgtgttgt tttaatatat atgcagcacc
    12181 taatatagct gctgcatgaa aatcatgtcc acaagcatgc atatgaccat caatctttga
    12241 acgatatggt agttctgtct tttcctgtac aggcagtgca tcaatatcac aacgcaacgc
    12301 gacaatgggt gcactgcctg taccaatttc agctaccaat ccagttttca agggaatttg
    12361 taaaattttg attcctgctg actgtaaatt tactctcaat ctttttgtcg tttctacctc
    12421 tttataagat aattccggat gttcatgaaa ccaataaaat tcttctgtaa tttttctttg
    12481 tattaattgt tcattcatat taaccccctt taatctatac atttttagta tattttttta
    12541 ttactaaaaa tcctattttc gtatactcca aaaacaaaaa aaaccaccat ctctgatata
    12601 cagagacggt ggtccgtggt cccactctgt ttacaacaaa ctgctgtaac tcaaaaccat
    12661 taacggcggc aaccggattt agcctactat aagttcaact aatctgctct caaaggcatt
    12721 ccattgtgct aagattattg tgaattttca gcctttgatt cacatctctg taacactttt
    12781 tcacaatgta cttattttga tcattgcatt tttaatgttt accattatgg tacacttata
    12841 ttttcccctt gtcaagattt tttttatctt ttttaaaaat aactaacaac cctacactca
    12901 aaaatacatt atactgataa gcatatattt aactcaatat ttttttaaat ccttagtttt
    12961 tttcgaacga catccaattc ctttatcata tccgctgcgt ttttatagtt tccatctgca
    13021 tattcaaaaa caaaagctgc ttgcgacgca tactgcttaa ttatctccat aagacttcgc
    13081 caagcaatcg tacctgcgaa taacggcaag tgttcatcaa tttttccgtt attatcctgg
    13141 agatgaagcg cactaatccg tcggtttaac tccctaataa cacggcaagt atcccagtta
    13201 ttaatatgtg catgccctac atcgataata gctcccgctg tctgaaattc ttcaaaaaga
    13261 gcgacatatg cctcttcatc aaaaagatta ttttgtttta atcctacgtt ttctatcccc
    13321 attttagctc catccaactc gtttgctaat agctcaattc tgcgcagccg ttccaatacc
    13381 agttgacgac aaaattccat atctccgctc cactgttcat tggtatgaac aacaacatat
    13441 tttgcccctg ttttttttgc atacaaaaac gtttttctat atcgttctaa atatgccgta
    13501 tcgtttgggt ctgctaaatt tacagtaacg catggcccat gaatagacaa tgtctttttg
    13561 tctgcccgca tgcgatgcaa tacaacgtcc caatagctat cactgccaaa ttcataaaag
    13621 aattcaatgc cgtaatcttc cggcagtttt tccatttcta tttcattaaa tgctgaaaat
    13681 gcaagatcac taatttctat aattgccata tttattttct cctttttcac gaacatataa
    13741 atttatttct gtttctctat caaaaaacaa aacattttcc cataaaaatt gtattcctac
    13801 attttcaccg gcttttattt cataagtttc gcctgcaaac tgactaaata tagctgtacc
    13861 atcagccaaa tacagctgtg tcgtttgtaa atttcctgta ttttccgtat accggcaact
    13921 ccctttgagc atagcccgat catccgtagt aatatgtatg ttttccggac gaataccaac
    13981 aataacacta tgtttccctg ttaacactgc cgtaatccga tccggcagcg gaactgcaac
    14041 tttccctata aaaagatgtc catcgacaat atctgccgtt atcagattca tcgccggcga
    14101 accgataaaa gaagcaacaa atgcattaga tggattatca taaatttcac gaggtgtcgc
    14161 aatctgctgc aatgtaccat cacgaagtac agcaatccgc tgtcctaccg tcatagcttc
    14221 tacctgatca tgggtgacat aaatcatagt cgatttattt atttcatgaa ttctgactaa
    14281 attttgccgg gcttgctgcc gcaattgagc atccaaatta gataacggtt catcaagaag
    14341 aaaataggga gattgcttaa caatcgctcg gcataatgca acacgctgct tttgtccacc
    14401 cgacaaagac tttacaagac gttgttcaaa tccatccaga tgaagcattt ccaacgcatc
    14461 ttttgctctt ttttcaattt cttttttacc cagtttttga atttttaaac caaaaataat
    14521 attttcccat acatccatgt gaggaaataa agcataactt tgaaatacca ttgcaatatt
    14581 tcgttttccc ggtgccatat tattaacaca ggttcccccc ataaacaact tcccgtcagt
    14641 aatatcttca aatcccg
//
