LOCUS       c00056_NZ_FQVI..       14262 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FQVI01000030.1 Lactonifactor longoviformis DSM 17459, whole
            genome shotgun sequence.
ACCESSION   NZ_FQVI01000030
VERSION     NZ_FQVI01000030
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:54:57
            Original ID  :: NZ_FQVI01000030.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14262
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14262
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[199:4262]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      200..4262
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..14262
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14262
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(200..1309)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_1"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 2.2e-16,
                     bitscore: 51.6, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPTPCYVVDISRLKGNLEILKGVADRTGCEILLAQKAFSMYSLYP
                     LIGEYLSGCTSSGLCEARLGAEEMGKENHIYSPAYRAEEFPAICGLCSHIIFNSFAQLE
                     KYGPAAIERGRSVGLRINPQYSTQEAHAIYDPCATGSRLGVTLENFRPDLLENVEGLHF
                     HTLCEQDAYDLDATLEVIEEAFGPYMERMKWINFGGGHHITRPGYHIEVLEKCIRRIQN
                     RYQVQVYLEPGEAIALDAGYLVTEVLEIVKNGTDTAILDTSAACHMPDVLEMPYRPPLR
                     ESGEPGEKSYTCRLAGPTCLAGDIIGDYSFDHRLAPGERLVFEDMAIYSMVKNNTFNGM
                     RLPGIAVLEEDGECRIIKEFGYEDFKMRL"
     CDS             complement(1326..2528)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_2"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 6.6e-42, bitscore:
                     136.0, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 4.8e-40,
                     bitscore: 128.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKALIIGCGGVASAAIHKCCQNSEVFTEICIASRTKAKCDALKE
                     KLEGTTSTKITTAQVDADHVDELTALIKKEKPDVVLNLALPYQDLTIMDACLAAKTHYI
                     DTANYEPEDTAKFEYKWQWAYREKFEKAGITALLGSGFDPGVTGVFSAYAQKHYFDEIH
                     YIDILDCNAGDHGYPFATNFNPEINIREVSARGSYWENGSWVETEPMEIKKVYDFPEIG
                     EKDMYLLHHEELESLALNIKGIKRIRFFMTFGQSYLTHLKCLENVGMTSIEPIEFEGKQ
                     IVPLQFLKAVLPDPSSLGPRTKGKTNIGCIFRGIKDGKERNLYIYNVCDHQECYREVGS
                     QAVAYTTGVPAMIGAMMVMTGKWLKPGVFNVEEFDPDPFMEALNRWGLPWKTEEQPELV
                     D"
     CDS             complement(2546..3421)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_3"
                     /sec_met_domain="Arginase (E-value: 3.3e-75, bitscore:
                     244.7, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNKNIEVFIGCEAEYEEAGIVLYGAPYDSTTSYRPGARFGSKAM
                     RSESFGLETYSPYQDKDLTDLKVFDSGDLELCFGDSSLALEDIERRAEAILEDGKLPVL
                     LGGEHLVTLGAVRAVFKRHPDLHVIHFDAHADLREDYLGARLSHACVLRRCWELLGDKR
                     IHQFGIRSGDREEFCWGERGHVDTRRFDFQGLAETIETLKGRPVYFTLDLDVLDPSVFP
                     GTGTPEAGGVTFDQLRDAVELVCRGTKIAGCDIVELCPGYDPSGISTATACKVLREMLL
                     ALGEQRQVII"
     CDS             complement(3411..4262)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_4"
                     /sec_met_domain="Spermine_synth (E-value: 4.8e-60,
                     bitscore: 193.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 2e-19, bitscore:
                     61.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWFSERHTQNVKFSIRVERQLYSGQSEFQRIDVFDSREFGRFL
                     TLDGYLMLTEKDEFIYHEMMTHVPMAVHPDPRKILVIGGGDGGVIRELTRYEKIERIDM
                     VEIDPLVVEVSKKYLPQTACRLEDPRVHIYYEDGLRFIRSVHEEYDLIIVDCSDPGGPG
                     EGLFTKEFYGSCYKALKDDGIMVNQHESPFYEEDAMTMQRVHKRIVGSFPISRVYQVHV
                     PTFPAGHWLFGFASKKYHPVRDLDAVKWNMFGLSTRYYTTQLHAGAFALPYYVEEMLKH
                     VE"
     CDS             complement(4345..5790)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_5"
                     /sec_met_domain="OKR_DC_1_C (E-value: 7.3e-15, bitscore:
                     47.1, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 1.3e-126,
                     bitscore: 414.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLSQERAPVYEALEEFRRMRVVPFDVPGHKRGRGNKELREFLGE
                     KCVSLDVNSMKPLDNLCHPVSVIREAEELAAEAFGASHAFLMVGGTTSAVQSMVLTACK
                     RGDKIILPRNVHRSVINALVLCGAVPVYVNPDVDHQLGIALGMKVSQVEQAIKENPDAV
                     AVLVNNPTYYGICSDIKSIIALAHAHGMMVLADEAHGTHFYFGDNLPAAAMKAGADMAA
                     VSMHKSGGSLTQSSLLLTGPEVNPGYVSQIINLTQTTSGSYLLLSSLDISRRNLALHGR
                     ETFCQVVELAEYARAEINAIGGYYAYSRELVNGDSIYDFDVTKLSVYTLEIGLAGIEVY
                     DLLRDEYDIQIEFGDIGNILAYLSIGDRRQDIERLASALAEIKRLYQKSRNGMMSQEYI
                     SPQVVVTPQDAFYARKESLPLKETAGRVCSEFVMCYPPGIPILAPGERITDKILDYIVY
                     AREKGCSMTGPEDEKIEALNVLL"
     CDS             complement(6363..8879)
                     /locus_tag="ctg56_6"
                     /transl_table=11
                     /translation="VYSYASVPIIALFCYSFLLVSFLAARKNKIINSFIGLLVIMIMWT
                     GGSFFMRMGLWPYEKFWFHVSLIGMMMMPVGFLGFIREFMEVKSNHRKGFWSVLVLIIM
                     GVNIKTGVFVAAPEMKEIATGQVTYIYDIHWPVIVLFLTEAFILLDCAWMIYKNGHRNA
                     VVMKKLNPILLGIFILFLGHVLLVFPFFKGFPIDLMSGIINAFLMFYALYKKRLFKLTL
                     LISRGNCYALAIVLAVVIFYNLVRPLEELLSGLFHLGDSQRVMAIAVLVMLVTMGMYAI
                     LKKFFDELFVKDELVQTENLRDFSSKVSKSLNIQEILTELIEIIQKTISVEKVYICIED
                     DKGEYKMVQSTSPLNRRDFVLAKDHPVVEYLKKSDGCLLMREFKRTVAYKSMWEEEKHQ
                     LAVWKIECFVALKDEEDIIGIVMLSNKLKHERYTYNDISFLTSVDSVSSIAVKNSRLYE
                     KAYEEARKDELTGLLNRKCFYEVLDEAYERFKDSSLALIILNIDDFKLYNQLYGDQEGD
                     IALQRVAAIIQASAGEKSYVARYSGKEFAIILPQYDLHMAKKLAENIAAQIRDMNRHSK
                     EYALKALTVSCGICGIPFSASNPHELVNNADMAVYHVKRSGKNAVMIYSVGQDQKFAMQ
                     APEQSYKKSVYSEYASTIYALTAAIDTKDHYTFSHSKNVAYYASELAKAYGMNQECVNI
                     VHEAGLLHDIGKIGIPEDILNKPGKLTDEEYEIMKGHVEHSIGIIRHLPSLDYVIPAVI
                     GHHERYDGRGYPRRIAGEDIPIMARMLCVADSFDAMISKRSYKPSMEVDKALGILEEEA
                     GRQFDPKLVPIFTELVKSQTVEIQLD"
     CDS             complement(8872..10497)
                     /locus_tag="ctg56_7"
                     /transl_table=11
                     /translation="MRFEEKLKEFPKEAIWSEYCGFLDLDIREYMQIQNRLLKEQIRLW
                     SSSSLGQSFLKGKFPGTIEEFRAMVPLTTYDDYADVLLARRKEMLPEEPVIWIQTTWEG
                     GKHPIKAAPYTQGMLKTYQNNVLACLILSTSSKKGEFDVSAADNILYALAPLPYPTGLF
                     PVALGDEIGIGFLPPVKDAVEMSFKERNVKGFQMGLKKGIEFFFGMGSVAYYVSLSVAA
                     MGSGGSSKGLKKLAGISPSMLLRLAKAKKICKEENRQLKPKDLFQLKGFMCAGTDNRCY
                     KDDLEDLWGIRPMELFAGTEPSCIGTETWTRNGMYFFPDTCFYEFIPEAEMEKNMEDST
                     YQPRTVLMDEVQEGEKYELVLTIFKGGAFARYRVGDVYRCAGLTNKEDETKIPRFQYVD
                     RVSSIIDIAGFTRISEYSITRAIELSGLPIKDWIAQKEYKDNRRPVLHMYVEMEAGCLA
                     NHAVSQMILKEHLGIYFKYIDEDYQDLKKILGMDPLEITILKCGTFDRYRLETEKNIRH
                     MSPPAREVQDLLRAEGDKGGIRRV"
     CDS             complement(10487..11074)
                     /locus_tag="ctg56_8"
                     /transl_table=11
                     /translation="MTYTIAGVVGFLLFVLYDINSVLWRKKSLHCGFFAGNVLIIGATI
                     MLIKRVWNEAFVSMGSILCGLLALFFLGLLIYTLFFALPFGETYQTMDGRPQVCSAGVY
                     ALCRHPGVLWFFFFYLFLGLSFHSLQLAGAGMVFSLCNLGYVILQDIWTFPRSLGGYEE
                     YKKRTPFLIPTKGSLLACLTTLRERGRKEHEV"
     CDS             complement(11089..11448)
                     /locus_tag="ctg56_9"
                     /transl_table=11
                     /translation="MSVLFIEYPKCSTCQRAKKWLDSHGIEYTDRHIKEENPTSGELAD
                     WYRKSGLPLKRFFNTSGMIYRDMGLKDKLPLMTEEEQLELLGTDGMLVKRPLIIGDDFV
                     LTGFKEKEWEEALCS"
     CDS             complement(11679..12893)
                     /locus_tag="ctg56_10"
                     /transl_table=11
                     /translation="MKKRGTLIALALCTALVFTGCSGSNSKDGKDSKNTGEKIDISDMK
                     DSDDLVKALDLKDLGKYMTLGQYKGLEGTKMVYEITDEDVNAQVNGTLFQNSAVVTDRP
                     VQDGDIVNIDYVGTVDGVEFEGGKGQNYDLTIGSGEFIDGFETGLIGATTGQEVDVNVT
                     FPDPYQNNTDLSGKNAVFHVTVNSISAPPELTDEWVAANTEYKTVDEYKASIRKMIEDS
                     NDDQSIYYLATSLFSQVQENSEIKEYPEDLVKQETQNYKDQIESMYAAAAGMTMDEFIE
                     AQGYTEETFNELAEEKGKERLQQKMIVQAIMNAEDMRITQEDYDKMVEDYAQRYGFESK
                     DTMIQSYGEDMVKDTILWNKVGDVLVENGKITDQTVDEGEADTSGASQGESDGSDAAQQ
                     EETAE"
ORIGIN
        1 ccataatctc tataaaatct ataataagca gatgagactc cgggaagtgg cttaaagaag
       61 aaagagcgca cgtttgttgg ggtaaggggg attatgcgct ttttactgct tttttcttac
      121 gctttccaca aaataaagag gggctgaaaa aatggagtta gagcaactcc attttttcac
      181 agccccccct tttgcccttt tacagacgca ttttaaaatc ttcgtatcca aattccttta
      241 ttattctgca ctccccgtct tcttccagca ctgcaatacc cggcagcctc ataccgttga
      301 aggtattgtt ttttaccatg gagtagatcg ccatatcttc aaacaccagt ctctcccccg
      361 gggcgagcct gtggtcgaag gaatagtcgc ctatgatatc tccggccagg caggtggggc
      421 cggccaggcg gcaggtgtag gatttttctc cgggttctcc gctctctctc agcgggggcc
      481 gatagggcat ttccaggaca tccggcatat ggcaggcggc ggatgtgtcc agaatggcgg
      541 tgtctgtacc gttttttact atctccagca cctcagtgac cagatagccg gcatccaggg
      601 caatggcctc ccccggctcc agatatactt gtacctggta gcggttctgt atccgccgga
      661 tgcatttttc cagcacttct atgtgataac caggccttgt gatgtggtgt ccgcccccga
      721 agtttatcca tttcattctt tccatatagg gaccgaatgc ctcctcaatc acctccaggg
      781 tggcgtccaa atcgtaggca tcctgctcgc acagggtgtg aaagtgaagg ccttcgacgt
      841 tttccaaaag atccggtctg aagttttcta aggttacacc cagacgggac ccagttgcac
      901 agggatcgta gatggcatgc gcttcctggg tggaatactg gggattaatc cgcaatccta
      961 cacttctccc tcgttctatg gccgcagggc cgtatttttc cagctgtgca aaggagttaa
     1021 aaatgatatg gctgcagagc ccgcagatcg cgggaaactc ttcggccctg taggcggggg
     1081 agtagatatg gttctctttt cccatctcct cggcccccag cctggcttcg cagagtccgc
     1141 tggaggtgca tccgcttagg tactcaccta tgagaggata cagagaatac atagagaatg
     1201 ctttctgcgc cagaaggatc tcgcatccgg tacgatctgc tacgcctttt agtatctcca
     1261 gattcccctt tagccgggat atatccacta catagcaggg ggtaggcaat tgttcccagc
     1321 gcatatcagt ctaccagctc cggctgctcc tctgtcttcc acggcagccc ccaccggttc
     1381 agagcctcca taaaaggatc cggatcgaat tcttcaacat tgaatacccc cggcttcagc
     1441 catttgcccg tcattaccat catggcgcct atcatagccg gaacccctgt ggtatatgcc
     1501 accgcctggg atcctacctc cctgtagcat tcctggtgat cacatacatt gtagatatag
     1561 agattccttt cttttccatc ctttattccc cggaaaatac agccaatatt cgtctttcct
     1621 ttggttctag gtcccagaga cgagggatcc gggagcacag cttttaaaaa ctgaagaggc
     1681 acaatctgtt ttccttcgaa ttcaatgggt tcaatggatg tcatgcccac attctccagg
     1741 cacttcagat gggtcaggta gctctgcccg aaagtcataa aaaaacggat tctcttaatg
     1801 cctttgatat tcagcgccag agactccagc tcttcatggt ggagcaggta catatccttc
     1861 tccccgattt ccggaaaatc atagaccttc ttaatctcca taggctccgt ctcaacccag
     1921 cttccgttct cccaatagct tcccctggct gatacttctc tgatattgat ctccggatta
     1981 aagttcgtag caaagggata tccgtgatcc cccgcattgc agtccagtat gtcaatgtaa
     2041 tgaatctcat caaaatagtg cttttgggca tatgcagaaa aaacaccagt cactccaggg
     2101 tcgaacccgc ttcctaaaag ggcagtgatt cccgctttct caaacttctc tctgtaggcc
     2161 cactgccatt tatattcaaa cttggccgta tcctcaggct catagtttgc agtgtctata
     2221 tagtgtgttt tggctgccag gcaggcatcc ataatagtga gatcctgata gggaagcgcc
     2281 agattcagca caacatccgg cttttccttt ttgatcagtg cggtaagctc atccacatgg
     2341 tctgcatcta cctgtgcagt tgtaatcttt gtgcttgtag ttccctccag cttttccttc
     2401 agtgcatcac attttgcttt tgttctgctt gcaatacaga tttctgtaaa tacttcgctg
     2461 ttctggcagc atttatggat ggctgcggat gcaaccccgc cgcagccgat aatcaacgct
     2521 tttcccatac ttatattctc cttttctata tgataacctg tctctgttcc cccagtgcaa
     2581 gaagcatctc ccgcagtacc ttacaggctg ttgctgttga aatcccgctg gggtcatacc
     2641 ccgggcaaag ctccactatg tcacaccctg cgattttcgt gcccctgcag accagctcca
     2701 ctgcgtccct cagctggtca aaggtaacac ctccggcctc cggtgtcccc gttccgggaa
     2761 atacactggg gtccagcaca tccagatcca gggtgaaata cacaggcctg ccctttagtg
     2821 tctcaatcgt ctccgcaagt ccctgaaaat caaatcgtct ggtatccaca tgtccccgtt
     2881 ctccccagca aaactcttcc cgatcccctg agcgtatccc aaactgatgg atccttttgt
     2941 cccccagcag ctcccagcag cgcctgagta cgcaggcatg ggacagtctt gcgcccaggt
     3001 aatcctccct caggtctgca tgggcatcaa aatgaatcac atggagatcc gggtgccgtt
     3061 tgaacactgc cctgacagca ccaagggtca ccagatgttc accgcccaaa agcaccggca
     3121 gcttcccgtc ctccagaatc gcctccgccc gcctctctat gtcttccagc gcaagggagg
     3181 aatctccgaa acacagctcc agatcaccgc tgtcaaagac tttcagatct gtcagatctt
     3241 tgtcctgata gggactgtag gtctccaggc caaaggattc gcttctcata gccttgcttc
     3301 cgaatctggc cccgggccgg taagaagtcg tggaatcata gggtgccccg tacagcacaa
     3361 tccctgcctc ctcatattcc gcctcacagc cgataaatac ttctatattc ttattcaaca
     3421 tgcttcagca tctcctctac ataatatggg agggcaaagg cccctgcgtg gagctgtgtc
     3481 gtataatacc gggtggaaag cccaaacata ttccatttga cagcatccag atcccggacc
     3541 ggatgatatt ttttcgaggc aaacccaaac agccaatgcc ccgccggaaa ggtgggaaca
     3601 tgcacctgat aaacccggct gatgggaaag ctccccacaa tgcgcttgtg tactctctgc
     3661 atggtcatgg catcctcctc atagaagggg ctttcatgct gattcaccat aatcccgtcg
     3721 tccttcaacg ccttatagca gctcccgtaa aactccttgg tgaacagccc ctcccccgga
     3781 cccccggggt ctgaacagtc cacaatgatg agatcatatt cctcgtgcac ggaacgtata
     3841 aaacgcaggc cgtcctcata atagatatgt actctgggat cctccagccg gcaggccgtc
     3901 tggggcagat actttttgga tacctctacc acaagggggt caatctccac catatcaatc
     3961 cgttctatct tctcatacct ggtcagttcc cggattacac ccccgtctcc tcctccgatt
     4021 accaggatct tcctgggatc gggatgcacc gccataggca catgcgtcat catttcatga
     4081 tatataaatt cgtccttctc tgtcagcata agatacccgt ccagggtcag aaaccggccg
     4141 aactccctgg agtcaaatac atcaatccgc tgaaattcac tttgtccgct gtaaagctgt
     4201 ctctctacac gaatggaaaa cttcacattt tgggtatgac gctctgaaaa ccataattcc
     4261 attttccacc tctccttatc ttctatattt tcctaaaatc cccgtctcct gcagacccct
     4321 tttgcgtcct ctcaaaacag gtctctatag caatacattc agtgcttcga tcttttcatc
     4381 ctcgggcccg gtcatggagc agcccttttc tctggcatac acaatatagt ccagtatctt
     4441 atccgtaatc ctctctcccg gagccagaat ggggattccc gggggatagc acataacaaa
     4501 ttcactgcac actcttcccg ccgtctcctt cagcggcagc gattccttcc tggcatagaa
     4561 ggcgtcctgg ggcgttacaa ccacctgggg acttatgtat tcctggctca tcatgccatt
     4621 cctgctcttc tgatacagcc gcttaatctc cgccagggca ctggccaggc gctcaatatc
     4681 ctgcctccgg tcaccgatag acagataggc cagtatattg ccgatatccc cgaattctat
     4741 ctggatatca tattcgtcgc ggagcagatc atagacttca atccccgcca gaccgatctc
     4801 cagggtatag acagaaagct ttgttacatc aaaatcatag atgctgtccc cgttcaccag
     4861 ctcccgggag taggcataat aaccgcctat agcattgatc tccgctcttg catattccgc
     4921 cagttccacc acctggcaaa acgtctctct tccgtggagc gccagatttc ttctggagat
     4981 atccaggctg gataaaagca gataggatcc gctggtagtc tgcgtcaggt taattatctg
     5041 gcttacatac cccggattca cctctggacc tgtaagcaga agagaactct gggtaaggct
     5101 cccccccgac ttgtgcatac tcaccgccgc catatctgca cccgccttca tagctgccgc
     5161 gggcagatta tccccaaaat aaaagtgggt gccgtgggcc tcatccgcca gtaccatcat
     5221 tccatgggca tgcgcaaggg caataatcga ttttatatcc gagcagatgc cgtaataggt
     5281 aggattattt acaagaacag ccactgcatc cggattctcc ttaatcgcct gctctacctg
     5341 tgacaccttc atccccaggg caatcccaag ctgatgatcc acatcagggt tgacgtacac
     5401 aggcactgct ccgcagagaa ccagagcatt aatcacactc ctgtggacat ttctcggaag
     5461 aataatctta tccccccgtt tgcaggccgt tagcaccata ctctgtaccg cagaggtagt
     5521 gccccccacc atcagaaagg cgtgtgacgc tccaaaggcc tctgccgcca gctcctctgc
     5581 ctcccggata acagatacgg gatgacacag gttatccaga ggcttcatgg aattcacatc
     5641 caggctgaca cacttttctc ccagaaattc tcttaattcc ttatttcccc gccctctttt
     5701 gtgtccgggg acatcgaacg ggaccaccct catcctcctg aattcctcca gtgcctcgta
     5761 gacaggagcc ctttcctgtg aaagactcat tggcctcctc tcctttctat tcacctgatt
     5821 atgtgcaata gacgcctgta tccagtcctg catccgtata ttagatggtc tgccgcagtg
     5881 tgagccacgg agggtttttt attacatagg gaacaaaatt acctatgtaa taaaaaaacg
     5941 caggcaacag gcagtctacc gcccatcact tgcgtttcat cgtcttttct gattttgttt
     6001 tatttgaaaa cagaggctat ggcctgcagg cccccctgtt cctatttatt caaaatgcag
     6061 ttgagaatta gagtctatat agcaaacatt ttacttttac cactcttatt gaccgtttca
     6121 caagttgatg tgcagcaatg cactggtttt gagtaaccaa cttataaaat ttgagctttt
     6181 aactcaatca ataaggcaac gaaagttgcc aatcggcagt tgacccggct gtccgtatgg
     6241 ccttaactca taatgagtgg tcaaaaaata tttgcatgga aagctctaat tcaggaacta
     6301 tcatccatac aatggataac gtatcatatt tttatttttc tgtcaagaag aaagaagatt
     6361 tttcagtcca gctgaatttc aacggtctgg cttttcacca gttctgtaaa aataggaacc
     6421 agcttaggat caaattgccg gccggcctct tcctccagaa tgcccagcgc tttgtccacc
     6481 tccatacttg gcttgtagct tctcttggag atcatagcgt caaaggaatc tgccacgcaa
     6541 agcatccggg ccataatagg aatatcttcc ccagcaatcc gtctgggata cccccttccg
     6601 tcatagcgct catgatggcc gataacagcg ggtatgacgt aatccagaga gggcaggtga
     6661 cggataattc cgatggaatg ctccacatgt cccttcataa tctcgtattc ctcgtctgtc
     6721 agctttcccg gtttatttaa aatgtcctca ggaataccta tcttaccaat gtcgtggaga
     6781 agtcctgcct cgtgcacaat attgacacat tcctggttca tgccgtacgc cttagccagt
     6841 tcgctggcat agtatgccac attcttggaa tggctgaagg tatagtgatc cttggtatca
     6901 atcgcagctg taagcgcata gatggtagag gcatattctg aatacacact cttcttatac
     6961 gactgttcag gcgcctgcat cgcaaacttc tgatcctggc ccacagaata aatcatgact
     7021 gcatttttgc cggaacgctt cacatgatag actgccatgt ccgcattgtt caccagctca
     7081 tgagggttgg aagctgaaaa tggtattccg cagatcccgc agctcacggt aagggctttc
     7141 agggcatatt ctttggagtg ccggttcata tcccggatct gtgccgcaat gttttccgcc
     7201 agcttttttg ccatgtggag atcgtactgc ggcagaataa tggcaaattc cttcccgctg
     7261 tatcttgcca catagctttt ctcccctgcg cttgcctgta tgatggccgc cactctctgg
     7321 agggcaatat ccccctcctg gtccccgtac agctgattat acagcttaaa atcatcgata
     7381 ttcaggataa taagcgccag agaactgtct ttaaatcttt cataggcttc gtccagaacc
     7441 tcgtaaaagc atttccggtt gagcagaccg gtgagctcat ccttcctggc ctcctcataa
     7501 gccttttcgt aaagtctgga gttcttaacc gcaatagagc ttacggaatc tacagaggta
     7561 agaaagctaa tatcattgta ggtatacctc tcatgcttca gcttattgga cagcattacg
     7621 ataccaatga tatcctcttc gtcctttaag gcaacaaagc actctatctt ccagacagcc
     7681 agctggtgct tctcctcctc ccacatagat ttataggcaa ccgtccgttt aaattctctc
     7741 atcagcagac agccgtctga ctttttcaga tattctacta cgggatgatc ctttgccagc
     7801 acaaagtccc gacggttgag gggactggtg ctctgcacca tcttatattc ccccttgtca
     7861 tcctctatgc agatatatac cttttccaca gaaatggttt tctgtataat ttcaatcaat
     7921 tcagtaagaa tttcctggat gttcagggat ttggatacct ttgagctaaa gtcacggagg
     7981 ttctccgtct gcaccaattc atccttcacg aacagttcat cgaaaaactt tttaagtatc
     8041 gcatacatac ccattgttac cagcataacc aggaccgcaa tcgccataac tctctgggaa
     8101 tctcccagat gaaacagtcc gctcagcagt tcctccaagg gccgaaccag attatagaaa
     8161 atcaccacag ccagaacaat ggccagggca taacagttcc ctctggaaat caaaagtgta
     8221 agcttaaaaa ggcgcttttt gtacagtgca taaaacatta gaaaagcatt gataattcca
     8281 ctcatgagat caatgggaaa ccctttaaaa aacgggaata ccagcagtac atgtccaagg
     8341 aaaaggataa aaatccccag caggatcgga ttgagcttct tcatgaccac agcgttgcgg
     8401 tgcccattct tatagatcat ccaggcacag tcaagaagga taaacgcttc tgtaagaaaa
     8461 aggacaatca ccggccagtg aatatcataa atataggtta cctgccccgt ggctatctct
     8521 ttcatctccg gtgcagctac aaagactcct gtttttatat tcacgcccat gataatcaga
     8581 acaagaacag accagaaccc tttgcgatga ttacttttaa cctccatgaa ttcccggata
     8641 aatcccaaaa atcccacagg catcatcatc atgccgataa gagatacatg aaaccagaac
     8701 ttttcatagg gccacagccc catgcgcata aaaaaggaac cgccggtcca cattatcata
     8761 ataaccagga ggccaataaa agaattaata atcttatttt ttctggcagc caggaaggac
     8821 accagaagga aggaataaca aaacagtgca ataatcggca cacttgcata actatacacg
     8881 tcttatccct cctttgtcac cctctgcccg cagcaggtcc tgtacttccc gggccggagg
     8941 actcatatgc cggatatttt tctccgtctc cagtctgtag cggtcaaacg tgccgcattt
     9001 taatattgtg atctcaagag gatccatccc cagaattttt ttcaaatcct ggtaatcctc
     9061 atcaatatat ttaaaataaa tccccagatg ctctttcagg atcatctggc ttaccgcatg
     9121 gttggcaaga cagccagcct ccatctccac atacatatgt aatacaggtc tccggttatc
     9181 cttatattcc ttctgtgcga tccagtcctt gatcggaagt ccggacaact ctatggcccg
     9241 cgttatggaa tactcagaaa ttctggtaaa tcccgctata tctatgatcg aggacaccct
     9301 gtccacatac tgaaaacggg ggatctttgt ctcgtcctct ttgttcgtaa gccccgcaca
     9361 ccggtataca tctcccaccc ggtatctggc aaaagcccct cccttaaaaa tggtaagtac
     9421 cagttcatac ttttcgccct cctgtacctc atccatcaga actgtccggg gctggtaggt
     9481 actgtcttcc atattcttct ccatctctgc ctccggaata aattcataga aacaggtgtc
     9541 cggaaaaaaa tacattccat tcctggtcca ggtctctgtc ccgatgcagc tgggctccgt
     9601 ccctgcaaaa agctccattg ggcggattcc ccagaggtct tccaggtcgt ccttgtagca
     9661 tcggttgtcc gtacccgcgc acataaaccc tttcagctga aacaaatcct taggcttcag
     9721 ctgccggttc tcctctttgc atattttctt tgccttagcc aggcgcaaaa gcatagacgg
     9781 ggagatccct gccagttttt tcagtccttt ggaggagccg ccgcttccca tggcagctac
     9841 actcaggctt acgtaatagg ccacacttcc catgccgaag aaaaactcaa ttcccttctt
     9901 caatcccatc tgaaaccctt ttacattccg ctccttaaag gacatctcca cagcatcctt
     9961 caccggaggc agaaagccaa tgccgatctc atccccaagg gcaaccggaa acagcccggt
    10021 agggtagggc agcggggcaa gggcgtacag gatattatcc gctgcactta cgtcaaattc
    10081 cccttttttg ctgcttgtgg acaaaatcag acatgccaga acattgttct gatacgtttt
    10141 cagcatcccc tgggtgtagg gtgctgcttt gatcgggtgt tttcctccct cccaagtggt
    10201 ctggatccag atcacaggct cctccggcag catttccttt cgcctggcca gcagtacatc
    10261 tgcatagtca tcgtatgtgg taaggggtac catagcgcgg aattcttcta tggttccggg
    10321 aaatttcccc tttaaaaagc tttgtcccag ggaagagctg ctccacagac ggatctgttc
    10381 ctttaagagc ctgttttgta tctgcatata ctccctgata tcaagatcca aaaatccaca
    10441 gtactcactc catatcgctt ctttaggaaa ttcttttaac ttttcctcaa acctcatgtt
    10501 ccttccgccc cctttcccgc agtgtagtaa ggcaagccag taagctcccc tttgtaggaa
    10561 ttaaaaaagg agtcctcttt ttatactcct cataaccgcc caagcttctg ggaaacgtcc
    10621 atatatcctg cagaatcacg taccccagat tgcacaggct gaacaccatg cctgcccccg
    10681 caagctgcag ggagtgaaaa gacaggccca gaaacagata aaaaaagaaa aaccacaaaa
    10741 ctcccggatg ccggcaaagg gcgtacaccc ccgcgctgca gacctggggt ctgccgtcca
    10801 tggtctgata cgtctcccca aacggcaggg caaaaaatag agtataaatg agaagcccta
    10861 aaaagaacag tgccaacagg ccgcataaaa tagaacccat tgacacaaac gcctcattcc
    10921 atactctttt tatcaacatt atggttgcac ctataataag tacattaccc gcaaaaaagc
    10981 cacagtggag acttttcttt ctccacagta cactgtttat atcatataat acgaataata
    11041 aaaagccaac aactcccgca atcgtataag tcatactgtt ccctctgctc agctacacaa
    11101 ggcttcttcc cattccttct ccttaaaacc tgtcagtaca aaatcatccc ctataataag
    11161 aggccgcttt accagcatac cgtctgtccc caaaagctcc agctgctctt cctctgtcat
    11221 caaaggcagc ttgtctttca gtcccatatc acggtaaatc attccgctgg tgttaaaaaa
    11281 gcgcttcaac ggcagtccgc ttttcctgta ccaatccgcg agctctccgc tggtgggatt
    11341 ctcttctttt atatgccgat ccgtatattc aattccatga ctgtccagcc acttttttgc
    11401 acgctggcag gtactgcatt tcggatattc tataaataaa acagacatta tcatactcct
    11461 taacttccag taatttgcat atcaaactta ttataatcga aaattctttt tcttacaacg
    11521 actttcatga agaaatttga acctttattg taatttaatg taatgttttg gtaataaatg
    11581 gaaacaatgc acaaaaaagg cccggtgaca aacgggcggt atcttactgt acgcctgctt
    11641 gtcaccgggt ctgtgataga tctgattcac gttctgtttt attcagctgt ctcttcctgc
    11701 tgggcagcat cactgccgtc cgattccccc tgggaggcgc cgctggtgtc tgcttccccc
    11761 tcatccacgg tctgatccgt aatcttgccg ttctctacaa gcacatctcc gaccttattc
    11821 cagagaatgg tatcctttac catatcttcc ccgtagcttt ggatcatagt atctttgctc
    11881 tcaaatccat atctctgtgc ataatcttct accatcttat cgtaatcttc ctgcgtgatt
    11941 ctcatatcct cagcattcat aattgcctgt acgatcattt tctgctgcag tctctctttg
    12001 cccttttcct cagccagctc gttaaaagtc tcttccgtat acccttgagc ctcaatgaac
    12061 tcatccatgg tcataccagc tgccgctgca tacatagatt ctatctgatc tttataattc
    12121 tgggtttcct gcttcaccag atcttccgga tattccttaa tctcggagtt ctcctgcacc
    12181 tggctgaaca gagacgtagc aaggtaatag atggattgat catcattgct gtcttcaatc
    12241 atttttctga tagacgcttt gtattcatcc actgtcttat attctgtgtt cgctgccacc
    12301 cactcatccg taagctcggg aggtgctgag atggaattca ctgtcacatg aaacactgca
    12361 tttttgccgg acagatccgt attattttga taaggatccg ggaaggtaac attgacatca
    12421 acctcctgtc ctgtggttgc ccctataagg cctgtctcaa atccgtcgat aaattccccg
    12481 gagccgatgg taaggtcata gttctgtcct tttccccctt caaactctac gccgtctacc
    12541 gttcccacat agtcaatatt gacaatatcc ccgtcctgaa ccggccggtc tgtcaccaca
    12601 gcagagtttt gaaataatgt accgtttacc tgggcattca catcttcgtc tgtaatctca
    12661 tacaccatct tagtgccttc cagtcctttg tactggccca gagtcatata tttgcccaaa
    12721 tccttaaggt ccagcgcctt taccaggtcg tctgagtcct tcatatcaga tatgtcaatt
    12781 ttttctcctg tattcttgct gtccttgcca tctttggaat tgctgcctga gcatccggta
    12841 aacaccagcg ctgtacaaag tgccagcgcg attaatgtac cccttttttt cattttttca
    12901 tcctttctag gctccctgtt atcgtatgaa tctattccat ttaaagtacg tcttagcgta
    12961 ctttctgcaa gcggggagtc ttatcttgtt tcaagataaa ggcttttcaa gttaaagcca
    13021 cacatgtgtt ataccataca tggctttaaa aagaaagcct ttcccgtcca tttcataatt
    13081 ttttcacatt cattctccca tggggggcac cggaacgggc cttgccgggt cgaatacttc
    13141 ccccacctga aacaggtcag aaagcttatt ggtgccttcc gtcatgtcat agtacatccg
    13201 gtagccatcc acgttccttc tcccctgccg gagatattca tcggtaatct ggacccatga
    13261 cgtatttgaa tctacattgc aaaaataacg gtacccctgg cttttcaaaa acctgtattt
    13321 ttcattctcc tgggtgtagg ggtgccagtc cccgatgtcc tccccgaagg caaagataat
    13381 cacatccgtg tcacccacaa taggcgctac ccttgtcttc cactttcttg tatcctccac
    13441 catctgctgg tagctgcagc tgtaggccct cagatgtccc caggtgtggc tggcgaactc
    13501 ccagccgtcc tttttcagtc cttctgctgc cgccctggcc tcccgaacct catgttcaaa
    13561 gttgaaatcc ggatttgcct ccaaaaactt cttctgatcc tcatccagat tttcacctgt
    13621 ctcatacgcc gtatctgtgc ggtaccctag gacaccgtta tatccggtaa gggcaatggt
    13681 tcccctggcg cctttataag caccgtcggg atgctcacgc agaaacgaat ccagcagagg
    13741 aaccacatcg taatccccca cggtaaccgt cccgtctgcg gcggtatact ggcacttggg
    13801 cctgccgtca ccgtccagaa caattttacc ggcgaatcca tccccgtcca tataatggta
    13861 atagctgaga tcatccacag agaggacaaa tggtttcttt ccctccggga gaaggatttc
    13921 cttcggcgcc atataggtcc tcccattttc atccgtcttt tctccggcca gatcctttag
    13981 ccttaccaac acgtaccccc gctcatacat ctgttccata attttagtga attcactgat
    14041 ggttgtcatc acctgattgt aggccccctc cttactgtcc ccgtcaaagg ccctggaagt
    14101 atctgcaatc agagagtgat aaaatatatg aggaatctcc tccacgtctg caggcctgca
    14161 ggcttctttc ctggccaggt acgccgcagc cgcttcctgc atttctttgg attctgcata
    14221 tccggggctc tttttcaaaa gagaaaccgc accgtcgtag tc
//
