LOCUS       c00024_NZ_FQVI..       15423 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FQVI01000029.1 Lactonifactor longoviformis DSM 17459, whole
            genome shotgun sequence.
ACCESSION   NZ_FQVI01000029
VERSION     NZ_FQVI01000029
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:54:57
            Original ID  :: NZ_FQVI01000029.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 39933
            Orig. end    :: 55356
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15423
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[49933:52486]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12553
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..15423
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15423
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             complement(395..1411)
                     /locus_tag="ctg24_28"
                     /transl_table=11
                     /translation="MKSKKSFRMVLTAMAAGTALLAVTAAGMGRYHIDPVTVVKILLSK
                     AVSLPVSWDAQAESVVWTLRLPRILTALMVGGALSLSGAAYQGVFKNPLVAPDMLGVSS
                     GACAGASLAILFGGNSIIVQVAAFAGGILAVGIATLIPKVVKNSSMMTLVLAGVIISGF
                     MNSILGLLKYLADPETQLASITHWQLGSLADSVWRDIVWVGPPVAAAAGILIILRWRVN
                     LLSLGEQEAKTLGVSIGRTRGLIIICATVLTASAVCISGTIGWIGLVIPHFSRIISGAD
                     NCRVIPVSGVLGAAFLLLVDTLARILTSAELPLSILTGLIGAPFYFYLLMKQRMELS"
     CDS             complement(1408..2583)
                     /locus_tag="ctg24_29"
                     /transl_table=11
                     /translation="LTKEGNEDMKNKKWKTKLAAAMMCILMGAAVLGGCGSEGKTQKDS
                     TEGQETQGKENGKEKEVSQGTRTVTDAAGNVVEVPEDLSKIAVVPIPWASVIYAIDGSS
                     ERLTAIHPTAMSAYTGCFLEKLDPHYGTADTSSIGKDFSINMEEWVNLGIQAAVIWDYE
                     TDEARQLKELGIAPIMVKNETVEELQASLKAMGQLLGKEDRAQQFMDAYTDTYEKIKSY
                     SDKVEQADKPKVLYLRNAQLDLQGNDNFIKEALELAGADNVAGDSTQKTMEEILEINPD
                     IILLSNFDTFLPSDLYENKIDGQDWSSVNAVINRRVYKAPMGLYRWDAPGVETPLMMEW
                     LAVLIQPEIFGDIHMETELEEYFKTYFNYELTEEDLGQIMQSEANASSKKP"
     CDS             2951..3877
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     66; E-value: 7.3e-21)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg24_30"
                     /sec_met_domain="HTH_1 (E-value: 4.8e-21, bitscore: 66.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKMTLQNLKYIIEIADSNSFSRAAKNLYVSQSTLSTAVQEVEQSL
                     GIRLFHRSNRGVTLTFDGEDFIRYAREIVEKSEYLENRYQTKNLLLMHFSVSCQHLPFA
                     VRAFNKMLNELELSNFDFAIRECNTASVIHDVASARSEIGILSSTEDHLEALRKNLSSY
                     DLDYTQLAVLPCYIFIRSKHPLAHKKHLSLKDMESFPFVTYDQENSHSHLTEEILFYNI
                     LSRNIHVSDRCTKIALIRNTDCFSIGSDLTNSNADAFHKGLGEIIPIPLEEPLGFLHAG
                     YITKKQYPLSQTGISYLEHLRHEIAAL"
     CDS             complement(4007..5392)
                     /locus_tag="ctg24_31"
                     /transl_table=11
                     /translation="MRETKLESNPEHTKAQWGNSFGYIMVAAGAAIGLGNIWRFPYLAY
                     AGGGGAFLVAYIILSVVFGYPIVKMESTVGRYGKSNAAADYGSVNKKFRFVGAVNILCE
                     FFVGVFYIVVSGWVLKYLVAFATGVDFGTDPSTFFDRHIEKAVSPNIYAGIVMVLVVFL
                     LFSGITELVEKVSKVIMPALLFILLACAVWALIKIPGAAKGLRYYLVPDFHDFTWKVFA
                     DVCSQVMFSVGIGCGIYSTLGASIPESHNIKKDSLMVIFCDTMVAFVAGLLVIPSVVGS
                     GMEMTSGKALVFEAMTMIFGNLPGGRAVGTLFFAALFFAVISTYVTVIEIPTVYVQEIL
                     KTTHKKALVVTSSVVYFLSIFVSLGFGALKNVKLPWPFATGIQMYDFYDWLDCFTGYFL
                     MPLGCLLICFFTVKVWGMDRYGKELLQDGRDGKITWYDKFSACVICPVILVIVLLNVFG
                     FIK"
     CDS             complement(5442..6731)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 90; E-value: 4.8e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg24_32"
                     /sec_met_domain="MFS_1 (E-value: 3.2e-28, bitscore: 90.0,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LEKKLSFKVLFTLVVLGACWSIVYIVPFIQYIWYNPFQDFLGATN
                     VQMGLLLTIYGFGNIFGAPIGGWVADRFNYKYVYVASVFLNGVLSLIFVISPNYVMAVI
                     CWIGFAVSSLFMNYPTHIKIVRELATDENQGKVFGINESMIGLFNIIFNAIMMAVYVKF
                     LEGVAGMKAAIIGIGLLSFVLTAIVAFVLDNPKKKKVSQAEVSPAEAPKGNLGKDFLVI
                     IKNPATWLVGISIFAVYSFLTTMSYFTPYFTDVLGVTVVFTGWVAILRQHGMTLIGAPV
                     GGWLTDKIKSPSKVLIGVYIVGILGFVYLLNAKTGVNAVVLITLTIVLSGIVYVGRGAY
                     YATITEAGVAREYTASTIGIAAALGFSPDLFQFTLFGHWLDNYGKTAYTYMFVFQTIVL
                     VIGIGAAFMIIRMSKKCKKAEDVKLDIESA"
     CDS             complement(6749..7645)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_33"
                     /sec_met_domain="PTA_PTB (E-value: 8.7e-44, bitscore:
                     141.4, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKNFDDLLDQVKRTEPRKVCVAVAEDRAVMTAVRDAAEMGFINP
                     ILVGNEKKIAAVGEEIGFKNYEIVGCSSEEESLVKAVTMVHNREADVLMKGLVNTAVYM
                     RGILNKEYGLRTGRLLSLLAVYQLPQYHKLIYASDSGINVAPDLEQKKVIMTNALEAMK
                     KFGLERPKTAILTANEMLDPKVISTVEAAALTEMAAKGEIPPCIPEGPISFDIAFDKAA
                     AEHKGIQSKIAGDVDLLIFPNIEAGNIMGKSWLHFNQAKWAGIVLGAAAPVILGSRSDT
                     PEIKINSIALACLAAAK"
     CDS             complement(7667..8728)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Butyrate_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_34"
                     /sec_met_domain="Butyrate_kinase (E-value: 5e-127,
                     bitscore: 414.8, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILVINPGGSSTKFSVFEDRQEILKRNIKHTGEDLQPFPTVFDE
                     YEYRTGIITKMLEEAGHSLDSFACVVGRGGLMRPVPGGTYRVNDRMVEDLKNAVNGEHA
                     SNLGAVIARNIGDAIGAPSFVVDPVAVDEMQDVARITGISDLEKKSWFHALNHKAVARK
                     TAEKMGGRYEDFNFIVAHLGSGISIVAHEKGRMIDGSGGRTDGPFSPERSGGLLTYQLI
                     ELCYSGRYSREEMVRKVSSCGGMYDYLGTKDMVEVEEMAESGDEKAGLIFRAFTYQVAK
                     EIALYGASLRGKVDRIIFTGGIAYSQKVVSEVSDRISYLAPIEVVPGEMEMEALALGAL
                     RVLNHEEEAKEYL"
     CDS             complement(8929..9717)
                     /locus_tag="ctg24_35"
                     /transl_table=11
                     /translation="MEGGDFMTDINIINAVDRALDMLIYMYNAGTEVSITKISEDMGVY
                     KSTVFRTLATLEAKGFVTKNPETEKYSLGIRLYIMGTSIGEKIGIQKLVKPYAKALHDE
                     FNEAVNVSILERNEKDIYRSVMIYKEENNQILRFNSEVGSRNDCHCAAVGKCLLAFSEN
                     IDLSIYDQRPMIKYTEHTIMTREALEKELEKVRQQGFAVDDEEREMGLTCIGAPILKNG
                     QYAVAAISLSGPTSRIKDETFQRKIDRLCQVTREISNSLR"
     CDS             10001..10216
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_36"
                     /sec_met_domain="Fer4_7 (E-value: 8.4e-15, bitscore: 46.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.2e-09, bitscore: 29.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.1e-07, bitscore: 22.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVTVKSARCKECGLCYSFCPKGAISFSQDTNASGYHPVMVDDEK
                     CIGCGTCYITCPDGVFHVLKSERGVL"
     CDS             10217..11275
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_37"
                     /sec_met_domain="PFOR_II (E-value: 1.8e-20, bitscore: 64.7,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 4.3e-47, bitscore: 152.2,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEMMKGNVAIAEAAVRAGVRFYAGYPITPSSEIMEYLSWRLSEV
                     GGSFVQAESELAGINMVFGASSCGVRAMTASSGPGISLKQEGISALSDEELPALVINMV
                     RYGNGLGTLFSSQCDYHRETHGGGHGDYRCIVLSPSSIQEAVDLIPTAYELGEKYRVVV
                     VLMSEGALGQMMEPVELPEFLEPKKNYWGFDGKYSYKKIGIFDRDSMKEAVELNKKYAE
                     IKEKEQRWESEGLEDADYVFVAYGLPGRSTLGAVRSLRDQGYKVGLIRPITTWPFPENA
                     FREVNPKVKAMITVEANATGQLVDDVALYTKKILKSDIPVYALPFVYGVPPMKEIQNKF
                     RQILADEIKEVY"
     CDS             11277..12023
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_38"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.6e-26, bitscore:
                     82.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAERKVPEMIDRPMSFCPGCGHGIIIRLICECLEELGQDQNVIF
                     PIGVGCSSNLGGGLVADRLHCLHGRAGAVATGIKRVNPDNLVITYQGDGDAYSIGIAET
                     TNAAYRNENITVITVNNTNFGMTGGQMSLTTMEGQKTSTTVHGRDCSVTGFPIRFPELV
                     ASQFHPAYVARGSVSSPANIKKTKGYIKKALQAQINREGYSMVEVMSPCPVNWGMKPIQ
                     AMERINNDLISYYPLGEFTEKGGETR"
     CDS             12020..12553
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_39"
                     /sec_met_domain="POR (E-value: 1.7e-37, bitscore: 120.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEVVCAGSGGQGVLTCGLILSDIAVREGQNATWCPSYGSAMRGG
                     TANCTVKFGKDVIYNPQQEEPDVLIVMNNPSFEMFIKIVAPNGMAVVGDMVTCDTTVRP
                     DVTIVKVPCSAIADELGNARSANIVMTGAAVKAMGDFSKEEAIAAMNAMFAKKGKSKFE
                     EANKKAFKAGYAAV"
     CDS             12925..14277
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ELFV_dehydrog"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ELFV_dehydrog_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_40"
                     /sec_met_domain="ELFV_dehydrog (E-value: 1.8e-10, bitscore:
                     32.3, seeds: 97, tool: rule-based-clusters)"
                     /sec_met_domain="ELFV_dehydrog_N (E-value: 4e-09, bitscore:
                     27.9, seeds: 410, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKRSLFYPLEQEDLTTLRLQYDWKTGNVFLQASKDWDPDLDWSK
                     YNHDFYVESIKTHNAKFLNDVETRAMFEKYGLTDYLEEVIDLLRQGKHFGIDCFYHKGF
                     DIKYLGNMHNRKRGINNTRHGVMKGGIRRHEKDENELDIIIDGLNLGRAMSFKNIAGEL
                     PVGGCKSCVIMDELDLTDMNVCGFLGFCLDEIRCSTGPDMGFPPAMTDVMKENGFSVQY
                     TCGPRGPLGSSGPPTAYGVFISLEQAVRFLNGSEDMTGMSFAVQGLGEVGAAMVGCIAK
                     FVKNPKIYVADINQQRVDEIVAKYKEQGIDISPASTDEILYLDVDVVSPCAMGAVLNEE
                     SIPKLNCKIIWGSANNQIKASSVEEECRLAKVIADRGILFQTDWWHNTAGVMFGYEEYK
                     YQKDASLERTYADIKRVLPKNTWENLNKAKELGITPTESAYKTCNDELYGA"
     CDS             complement(14808..15293)
                     /locus_tag="ctg24_41"
                     /transl_table=11
                     /translation="MMIPPAMVPADGDSLKTTNPIMVASNGVTNIKLVTSLVFLAINKA
                     FPQVNAAMALGKTPRYMTTRIWESGALDISWIPFGKNGRNKIAPAVILNMVISKGVYPW
                     ESSFLWYRLYPQKSMAVLRVQRIPTFMESTPSHKVRTRIPMNSIPMEIQPMAGIFSR"
ORIGIN
        1 gccagatgga tgatctccat ttcctccaac acttcctccg ccatgcgata atcttctcct
       61 gatggttttt caaatgctct cagataagga gcccggccca taactacaaa gtcacggacc
      121 agataaccgt atgcagctgt gtgtgtctga ggtacatatc cgatttttct ggcaacctct
      181 ctctgttcca tcctgtgcag agaaacaccg tcaagacaaa tttctcctct gcagggtctg
      241 agcagattgg caatacattt taaaagtgtt gattttcccg ctccattagc ccccaggaca
      301 gaaaaaatcc ttcccttgtc cagagtaaaa gatacatttt taaaaagaat tctgtctttt
      361 ccataagaaa aggatacgtc cttaatttct aacttcatga taactccatc ctttgtttca
      421 tcagcaggta aaaataaaag ggtgccccaa tgagtccggt taatatactt aatggaagct
      481 ccgcacttgt cagaattctg gccagtgtat caaccagcag caaaaaagca gcccccagca
      541 cccctgatac cgggattacc ctgcagttat ctgctccgga tattatccgg ctgaagtggg
      601 ggataacaag cccaatccac ccgatagttc cgctgataca tactgcactt gcagtaagca
      661 ccgtcgcaca tatgataatc agccctctgg ttcttccaat agaaacccca agcgtctttg
      721 cttcctgttc gcccagggat agaagattta ccctccatct caaaataatc agtatgcctg
      781 ctgccgctgc aaccggggga cccacccaca caatatccct ccacaccgaa tcagccagac
      841 ttcccagctg ccagtgggtg atggatgcca gctgtgtctc cggatctgca agatacttca
      901 aaagtcccag aatagaattc ataaacccac tgataataac gccggccagc accagcgtca
      961 tcatagaaga attcttcact accttcggaa tcagtgtagc aatccctact gccagaatcc
     1021 ccccggcaaa ggcagccact tgaacaatta tagaatttcc gccgaataat atagccaaag
     1081 aggcccctgc acacgcaccg gaggagacac ccagcatatc cggagctacc aggggatttt
     1141 taaatactcc ctgataagca gctcccgaaa gagagagcgc ccctcccacc ataagggcag
     1201 taagtattct gggcagccga agtgtccaca ccacactttc agcctgcgca tcccaggata
     1261 ccggcaggga taccgccttt gacaacagta ttttgacaac ggtaaccgga tcaatatggt
     1321 atcttcccat cccagcggca gtcactgcaa gaagtgctgt tcctgccgcc attgctgtca
     1381 gtaccatcct aaatgatttt ttgcttttca tggtttttta ctggaggcat tagcttcact
     1441 ctgcattatc tgccccaaat cttcctctgt gagttcataa ttaaagtagg ttttaaagta
     1501 ttcctctagt tctgtttcca tatgaatatc cccgaaaatc tccggctgta tcagcacagc
     1561 aagccactcc atcatcagag gtgtttcaac cccaggagca tcccagcggt aaagtcccat
     1621 aggtgctttg tatacccggc ggtttatcac tgcattaacg ctgctccagt cctggccgtc
     1681 tatcttattc tcatacagat cagaagggag gaaggtatca aagttgctca gtaagataat
     1741 atccggatta atctccagga tttcttccat tgttttctgt gtgctgtccc cggccacatt
     1801 atccgctcct gccagctcca gagcctcttt tataaaattg tcattcccct ggagatccag
     1861 ctgggcattc cgcagataga gaaccttggg cttgtctgcc tgctctacct tatcgctgta
     1921 cgattttatt ttctcatatg tatccgtata ggcatccata aactgctggg cacggtcctc
     1981 ctttcccaac aactgaccca tagccttaag gcttgcctgc agttcctcaa ccgtctcgtt
     2041 ttttaccata atgggcgcaa tgcctaattc cttcagctgc ctggcctcat cggtctcata
     2101 atcccagata accgcagcct gaatccccag atttacccat tcttccatat taatagaaaa
     2161 atctttgccg atactgctgg tatctgcggt accataatgg ggatccagct tttccagaaa
     2221 acaccctgta taggcgctca tagcggtggg atgtatggcg gtcagccgtt cagaacttcc
     2281 gtctatggca tagataaccg aagcccaggg aataggcacc actgcaatct tggagagatc
     2341 ctccggaacc tccaccacat tccccgctgc atctgttact gtgcgcgttc cctgtgatac
     2401 ttctttttct ttcccattct ccttaccctg tgtctcctgc ccctctgtac tgtccttctg
     2461 tgtcttgccc tcagaaccac atccgcccag tacggcagct cccataagaa tgcacatcat
     2521 tgcagctgcc agttttgtct tccacttctt gtttttcatg tcttcattcc cttcctttgt
     2581 caataaaaaa acctctccac gggaacatgg aaaggttaca acgacaacta catcgtcaaa
     2641 cccttatcca atgacccgtt ggatagagtt taccaacaaa atatttaagt atcctggctt
     2701 gacttcaaca tctggatatg acttcccgga cgtaatgtcc agtgtcctgc tatatccgac
     2761 tccgtcttac agtggcggca ccgcatcggt ttttcaccga tttccataaa atattttgct
     2821 tataatttct tgtattgtat cacacaaagg atagggaatc aagaattgtt cctatctgca
     2881 tttttcattg ccagctatca atttttttga tagtatagac tcaaaataac aaagagggaa
     2941 ccatatcata atgaaaatga ccttgcagaa cttaaaatat attatagaaa tagcagacag
     3001 caattccttc tccagagcgg caaaaaacct ttatgtatct cagtcaacct tgtcaaccgc
     3061 tgtgcaggaa gtagaacaga gtctgggcat acgccttttt caccggagca acagaggagt
     3121 aactcttacc tttgacggag aagattttat caggtatgca cgagagatag tagaaaaatc
     3181 tgagtatttg gaaaatcgat atcagacgaa aaatcttctg ctcatgcatt tttccgtctc
     3241 ctgtcagcac ctgccatttg cggtaagagc ttttaataaa atgctgaatg aattagaact
     3301 atccaatttt gatttcgcca tacgggaatg caatacagct tccgttatac acgacgtagc
     3361 atcggcaaga agcgagattg gtattctttc ctccacagaa gatcacctgg aagcgctgag
     3421 aaagaatctt tcttcctatg atctggacta tacccagctt gcagtacttc cctgttacat
     3481 atttattcgg tcaaaacatc ctctggctca caaaaaacat ctctccttaa aagacatgga
     3541 atccttcccc tttgtcacct atgaccagga aaacagccac tcccatttaa cagaagaaat
     3601 actattctac aatatactca gtagaaatat tcatgtaagc gatcgctgta caaagatagc
     3661 cttaatccgg aataccgact gcttcagcat aggatccgat ttaacaaaca gcaatgcaga
     3721 tgcatttcac aaaggtctgg gggaaatcat cccaatccct ttggaagaac cacttgggtt
     3781 ccttcatgca ggatatatca caaaaaagca atatccctta agccagaccg gcatctccta
     3841 cctggagcac ctgagacatg aaattgcagc cttatagtat aatttgggac gtaatttggg
     3901 acgtgttcct tttagaaaga acacgtccca aattaggatc agggtgtccc tttttcggac
     3961 tgacctgtcc cctttttata gtttaccttc tcctatttga cacatgctac tttataaacc
     4021 caaacacatt cagcagcaca atcactaata tcaccggaca gattacacag gcagaaaatt
     4081 tatcatacca ggttatttta ccatcccttc catcctgcag aagctctttc ccgtaccgat
     4141 ccatccccca aacctttacc gtgaaaaagc agataagcag acaacccaaa ggcattaaaa
     4201 agtatccggt aaagcagtcc agccagtcat aaaaatcata catctgaatc cccgtagcaa
     4261 acggccaggg cagctttaca ttctttaatg ccccgaatcc aagagagaca aaaatactca
     4321 aaaaatatac tacactagaa gttacgacca gcgctttttt gtgagttgtc ttcaaaattt
     4381 cctgtacata taccgtaggt atctctataa ccgtgacgta tgtagaaatc accgcaaaaa
     4441 acagcgctgc aaaaaacagt gtccccacgg cccttccccc cggaagattg ccgaatatca
     4501 tagtcattgc ctcgaacacc aaggctttac ctgaagtcat ctccataccg ctgccaacca
     4561 ctgatggtat taccagaagc cctgccacaa aggcaaccat ggtatcacaa aaaatcacca
     4621 tgagagaatc cttctttata ttatgggact ctggtatact ggcccccagc gtggaataga
     4681 tcccgcaccc tatccccacc gaaaacatta cctgagagca gacatcagca aaaactttcc
     4741 aggtaaagtc atgaaaatcc ggtaccagat aatacctcaa tcccttagcc gcccctggta
     4801 tcttaatcaa tgcccagacg gcacaggcaa gcagaataaa gagcaaagca ggcatgataa
     4861 ctttagaaac cttttccacc agctctgtaa ttccgctgaa taacagaaac acaaccagaa
     4921 ccataacaat cccggcataa atattaggtg agacggcttt ttcaatatgc cggtcaaaaa
     4981 atgtactggg atccgtccca aaatcaaccc cggttgcaaa tgccacaaga tacttaagca
     5041 cccatccgct gacaacaata taaaatacac ccacaaaaaa ttcacagagt atattgacag
     5101 cacccacaaa acggaatttt ttatttacgc ttccgtagtc cgcggccgcg ttggactttc
     5161 catagcggcc cacagtactc tccatcttca ctataggata tccaaacacc accgacagga
     5221 taatatacgc caccagaaag gcgccccctc ctcctgcata ggcgagataa ggaaatctcc
     5281 atatattccc aagtcctatg gctgcgccag ccgcaaccat aatatagcca aaactattcc
     5341 cccactgagc cttcgtatgc tccggattac tctccaattt agtttctctc atagatcctt
     5401 ctcctttttt cggattaaaa gatgctggcc ggctttctat attaagcgct ttctatatca
     5461 agttttacat cctctgcttt tttgcacttt ttggacattc tgataatcat aaaagccgct
     5521 ccaattccga ttaccagaac tatagtctga aatacaaaca tatacgtata ggcagtcttc
     5581 ccatagttat ccagccaatg cccaaacaaa gtaaactgaa acaaatccgg ggagaagcct
     5641 aacgctgctg caattccaat ggtagaagca gtgtattccc tggcaactcc tgcttccgta
     5701 atcgtagcat aataggcacc tcttcctaca tatacaatcc ctgaaagtac gatggtaagg
     5761 gtaataagaa ccactgcatt tactcccgtc tttgcattca gcagatagac aaaccctaag
     5821 attcccacaa tatacacgcc tatgagtacc tttgaggggg acttgatttt gtctgtcagc
     5881 catcctccca ccggcgcccc aataagtgtc atgccatgct gtctcaggat cgctacccat
     5941 ccggtaaaca ctacggtaac ccccaataca tcagtaaaat aaggggtaaa atatgacatg
     6001 gtagtcaaaa atgagtaaac tgcaaagata ctgattccaa ccagccatgt ggcaggattc
     6061 ttaataatta caagaaaatc ttttcccaga ttccctttcg gagcctctgc aggggatact
     6121 tctgcctgag acactttctt ctttttcggg ttatccagaa caaaggctac aatagctgtc
     6181 aggacaaagg aaagaagtcc gattccaata atagctgcct tcatgcctgc cacgccttcc
     6241 aaaaatttaa catatacagc catcataata gcgttaaaga ttatattaaa caatccgatc
     6301 atagattcat tgataccgaa aacctttccc tggttctcat ccgtggccag ctcccgcaca
     6361 atctttatgt gagtggggta attcataaac agactggata ctgcgaatcc aatccagcag
     6421 ataactgcca tcacatagtt cgggctgatt acaaagatta atgacagcac accatttaaa
     6481 aacacagatg caacatacac atatttataa ttgaatcgat cggctaccca tccgccgata
     6541 ggtgcgccga atatattccc gaaaccatag atggtcagaa gcagacccat ctgtacattc
     6601 gtcgccccaa gaaaatcctg aaatggatta taccagatat actgtataaa cggcacaata
     6661 taaacaattg accagcaggc ccccagcacc accagggtga aaagtacttt aaaagataac
     6721 tttttttcca attttcgctc ctcctcttct acttggcagc tgccagacag gccaaggcaa
     6781 tagaattgat tttaatttcc ggtgtgtcag atcgggatcc gagaatcaca ggggctgcag
     6841 cacctaatac aattcccgcc cattttgcct gattaaaatg cagccaggat ttccccataa
     6901 tatttcccgc ctctatatta gggaagatca gcaaatctac atcccccgct attttactct
     6961 gaataccctt gtgttctgcc gcagctttat caaaagcaat atcaaatgaa atgggacctt
     7021 ccggaataca gggaggaatc tctccctttg cagccatctc tgttaaagct gcagcctcta
     7081 ctgtggaaat cacttttgga tccagcattt cattggctgt aaggatggct gtcttaggcc
     7141 gctccagtcc aaacttcttc attgcttcca gcgcattggt cataattacc tttttttgtt
     7201 ccagatccgg ggccacatta atcccgctgt cagatgcata gataagcttg tgatactgtg
     7261 gcagctggta aactgcaaga aggcttaaaa gccggccggt ccgcagtcca tattccttgt
     7321 tcagaattcc cctcatataa accgcggtat tcacaagccc tttcataaga acatccgcct
     7381 cccggttatg taccatagtt acggccttca ccagagattc ttcctcgctg ctgcacccta
     7441 caatctcata atttttaaaa ccgatttctt ctccaactgc cgctattttc ttttcatttc
     7501 ccacgagaat aggattgata aatcccatct ctgccgcatc tctgacggct gtcataaccg
     7561 cccggtcctc tgcgactgct acacatacct ttctgggttc tgtccgcttc acctgatcca
     7621 gcaggtcatc aaaattttta agcatactct cctccattcc tcatccctac agatactcct
     7681 tcgcctcttc ttcatgattc agtactctta gagctcccag cgccagcgct tccatctcca
     7741 tttccccagg taccacctca atgggggcca ggtaagagat tctatccgaa acctctgaca
     7801 cgactttctg agaatatgca attcctcctg taaaaattat tctgtcaacc tttcctctca
     7861 ggcttgctcc atagagtgca atttcctttg ccacctgata ggtaaacgcc cggaaaataa
     7921 ggccggcttt ttcatccccg ctctctgcca tttcctctac ctctaccata tccttagttc
     7981 ccaggtagtc atacattcct ccgcaggagc taaccttccg gaccatctct tcccgtgaat
     8041 atctgccgga atagcatagc tcgatcagct gataggtgag aaggccgccg ctgcgctccg
     8101 gtgagaaagg cccgtcagtg cgtcccccgc tgccgtctat catcctgcct ttttcatgag
     8161 ccacaataga gatgcctgac cccaggtggg ccacgataaa gttaaagtct tcatatctcc
     8221 cgcccatttt ctctgctgtc tttcttgcca ctgctttgtg gttcagggca tggaaccagc
     8281 tttttttctc tagatctgat atccctgtta tccttgcaac atcctgcatc tcatccacag
     8341 ctacaggatc taccacaaag gatggtgcgc ctatggcatc cccaatattc cgtgcaatta
     8401 ctgcccccag attcgaggcg tgctctccgt ttacagcgtt ctttaagtcc tctaccatac
     8461 ggtcattcac ccggtaggtt ccccccggaa cgggacgcat aagaccgcct cttcccacca
     8521 cacaggcaaa ggaatctaag gaatgacccg cttcttccag catttttgta atgatacctg
     8581 tccggtattc atattcatca aaaactgtag gaaatggctg taaatcctct cccgtatgct
     8641 ttatgttcct cttcagaatt tcctgtctgt cttcaaagac agaaaattta gtagaggaac
     8701 ccccgggatt aatcactaaa atcttcatgt tccatcctca cttctcagta catacttttg
     8761 attatggatg ttctagctaa tggaacatag ttctattatt gtttagtgta gcacctcttc
     8821 tttcccgatg tcaattcctt ttttgtcccc tttgctgact ttcatgattt tgcacaaaaa
     8881 taaagcatgc tctctggtaa ttaaaccaaa ggcatgctat attcttcttt accttaaact
     8941 gttggaaatc tcccgggtaa cctggcagag cctgtctatt tttctctgaa aggtctcatc
     9001 cttaattctg ctggttggac cagataggct tatggcagct actgcatact gtccattttt
     9061 gagaatcgga gctccaatac aggtaagtcc catttcccgc tcttcatcat caactgcaaa
     9121 cccctgctgc ctcaccttct ccagttcctt ttccagtgct tcccttgtca ttatggtatg
     9181 ctctgtatac tttatcatgg gccgctgatc atagatcgag agatcaatgt tctcgctgaa
     9241 tgctaaaagg catttgccca ctgccgcaca gtgacagtca ttgcgggatc ctacctcgga
     9301 gttgaacctg agaatctggt tgttctcctc cttgtatatc atgacactcc gataaatgtc
     9361 cttctcgttt ctttcaagaa ttgagacatt caccgcctca ttaaactcat catgaagagc
     9421 tttggcatac ggcttaacca gcttttgaat tcctattttt tctccaatgc tggtgcccat
     9481 aatgtacaga cggattccaa gagaatactt ttctgtctct ggattttttg tcacaaagcc
     9541 ctttgcctct aatgttgcca gagttctgaa tacagtactt ttatagactc ccatatcttc
     9601 actgatttta gttatagaca cctcagtgcc cgcattatac atataaatca gcatatccag
     9661 cgcccgatcc accgcattta tgatatttat atctgtcata aaatcacctc cctccatcct
     9721 gcagcttttt cgtcacttat ctttgacact accacaaagt attttaaatt tcaattattt
     9781 tttctgtatc tatgttttta tccttcaatg ggtatccctg cgtttttgtg cacattatac
     9841 ataaaaataa ttaattatta tccatttttc ataattttaa caaaatgata ttgacaaaat
     9901 aaagtcgtgg tgggtataat gcagttgatt atggaacata gttctagtgt ttggaacaaa
     9961 gctatgaaac taacaaagga aacttttagg aggtatttca atgaaagtta cagtgaaatc
    10021 ggccagatgc aaggaatgcg gactctgtta ttccttctgt ccgaaaggag ccatcagctt
    10081 ttcccaggat accaatgcct caggctacca tcctgttatg gtagatgatg aaaagtgcat
    10141 tggctgcgga acctgttata taacatgtcc ggatggcgtc tttcacgttt taaagagtga
    10201 aaggggggtt ttataaatgg cagaaatgat gaagggaaat gtggctatcg ctgaagcagc
    10261 tgtccgtgcg ggtgtccggt tctacgcagg ctatcccatt accccatcca gtgaaattat
    10321 ggagtattta tcctggcgtc tctctgaagt gggaggatcg tttgtccagg cggaaagtga
    10381 gcttgcagga attaatatgg tctttggtgc ttccagctgc ggagtcaggg ccatgactgc
    10441 ctcatcaggg ccgggtatca gcctgaagca ggaaggtatc tctgctctct ctgatgagga
    10501 gcttcccgca ctcgtaatca atatggtacg ttacggaaac ggcctgggaa ccctattttc
    10561 ctcccagtgc gattatcacc gggaaactca cggaggcgga cacggcgatt accgttgtat
    10621 cgttctatcc ccatccagta ttcaggaggc agtggatcta atccccacgg cctatgaact
    10681 gggagaaaaa taccgggtgg tagtggtact tatgtccgaa ggagctctgg gacagatgat
    10741 ggaacccgtt gaacttcccg aatttctgga acccaaaaag aattactggg gttttgacgg
    10801 aaaatattct tataaaaaaa taggtatctt tgacagagac tctatgaaag aggctgtaga
    10861 attaaacaaa aaatatgcag agataaaaga aaaagaacag cgttgggaat ccgaggggtt
    10921 ggaggatgcc gactatgtat tcgtggcata tggtcttccc ggcagaagta cattgggagc
    10981 ggtccggagc ctgagagatc aggggtataa agtgggtctc atccggccaa ttaccacatg
    11041 gcccttccct gagaatgcat tccgggaggt gaatccaaag gtaaaagcaa tgatcactgt
    11101 agaggcaaat gcaaccggac agctggtgga cgatgttgct ctctacacga aaaaaatact
    11161 aaagagcgat atacctgtat acgcacttcc atttgtctat ggtgtgcccc ccatgaagga
    11221 gatccagaat aaattccggc agattcttgc cgatgagata aaggaggtat actgatatgc
    11281 cagcagaaag aaaagtgccg gaaatgatag accggcccat gagcttttgc ccaggctgcg
    11341 gacatggtat cattatccgc ctgatttgcg agtgtctgga agaactgggg caggatcaga
    11401 atgtgatttt tcccataggg gtaggatgtt cttccaatct gggaggagga ctggtggcag
    11461 accggcttca ctgtctgcac gggagagcag gagcagttgc cacaggtatc aaaagagtga
    11521 atcccgataa ccttgtaatc acgtatcagg gagacgggga tgcctacagt ataggaattg
    11581 cagaaacaac caatgcggcc taccgcaacg aaaatataac agtaataaca gtaaataata
    11641 ccaattttgg tatgaccgga gggcagatga gcctgactac tatggaggga caaaagactt
    11701 caacgactgt tcatggacgc gattgttctg tcacaggctt tcctatccgt ttccctgaac
    11761 tggttgcttc ccagtttcat cctgcctatg tagccagagg ttctgtcagc agccccgcta
    11821 atattaaaaa gacaaaggga tacataaaga aagcacttca ggcccagata aacagggaag
    11881 gatactctat ggtggaagtc atgtctccat gtcctgtaaa ctggggaatg aagcctattc
    11941 aggctatgga acggatcaat aatgacctga tctcttacta tcctctggga gaatttacag
    12001 aaaaaggagg agaaaccaga tgaaagaagt agtatgtgcc gggtccggcg gacagggcgt
    12061 acttacctgc gggcttattc tgtcagatat tgctgtaaga gagggacaga atgccacatg
    12121 gtgtccatcc tatggttctg ccatgcgggg gggaactgcc aattgtacag tgaaattcgg
    12181 caaagatgta atctacaatc cgcagcagga agagccagac gttcttattg ttatgaacaa
    12241 cccttctttt gagatgttta ttaagattgt cgcgccaaat ggcatggcag tggttgggga
    12301 tatggttacc tgcgatacca cagtacgccc tgatgtaacc attgtaaaag tgccctgctc
    12361 tgccattgca gacgaactcg gaaatgcaag aagtgctaac attgtcatga ccggcgccgc
    12421 tgtaaaagct atgggcgatt tctcaaaaga ggaagccatt gctgccatga atgcaatgtt
    12481 tgccaaaaag ggaaaaagta aatttgagga agctaataag aaagctttca aggctggata
    12541 tgccgccgtg taactaactc tgcagaaggc atattagtaa aaatgacgaa gattaaaaat
    12601 agaacattgt tccattttta attataaaac atcctttttc ttcgataaat tttataagtt
    12661 ttgcactaat attggaaatc acttctaata ttttgcataa cacagccttt attttgaaat
    12721 tgtatgtcaa atatttttgt gaaaatgcaa gcaaaaattt ctttgacatt ttaaaagggc
    12781 tgtggtactt taaagaaaag gatgttgtct gttccgtaaa aagagcagga catacatcct
    12841 ttttttaaca aaatgagaaa tcatgcgcat gattccataa aagtacaagg gtgtgtagga
    12901 aaacaaataa aggaggattt ttgaatggaa aaaagaagtt tattctatcc attggaacag
    12961 gaagatttga caacattacg tcttcagtat gactggaaaa ccggcaatgt gtttcttcag
    13021 gcatctaaag actgggatcc tgatttagac tggtcaaagt acaaccacga tttctacgta
    13081 gaaagcatta aaacacacaa tgcaaagttt ttaaatgacg tagagacaag agctatgttt
    13141 gagaaatacg gtttaaccga ttatctggaa gaggttatcg accttttaag acagggaaaa
    13201 catttcggta ttgactgttt ctatcacaaa ggatttgaca ttaagtatct gggcaacatg
    13261 cataacagaa aacgcgggat caataatacc cgtcacggtg ttatgaaagg cggtatccgc
    13321 cgtcatgaaa aggacgagaa cgagctggat atcatcattg acggcctgaa cctcggaaga
    13381 gcaatgtcct ttaaaaatat tgcaggtgag cttcctgtag gcggatgcaa atcttgcgtt
    13441 attatggatg aactggatct cacagatatg aacgtatgcg gtttcctggg cttctgtctg
    13501 gatgaaatcc gctgctccac aggacctgat atgggattcc ctcctgcaat gactgatgtt
    13561 atgaaagaaa acggcttcag tgttcagtat acctgcggac cacggggtcc tctgggatct
    13621 tcaggaccgc cgacagctta cggagtattc atctctctgg agcaggccgt acgcttcctc
    13681 aatggcagcg aagatatgac aggaatgtcc ttcgccgttc agggtcttgg agaagtaggc
    13741 gcagctatgg taggatgcat tgccaagttt gtgaaaaatc ctaaaatcta cgttgcagat
    13801 atcaaccagc agcgtgtaga tgagattgtt gctaaatata aagaacaggg aatcgatatt
    13861 tctcctgcat ccaccgatga aatcctctat ctggatgttg acgtagtttc cccatgtgct
    13921 atgggcgctg tgctcaacga agagagcatt cctaaactta actgcaagat catctggggt
    13981 tctgccaaca accagatcaa ggcaagcagc gtagaggaag aatgccgtct ggcaaaagta
    14041 attgctgaca gaggaatcct cttccagaca gactggtggc acaataccgc cggcgtaatg
    14101 tttggctatg aagagtacaa atatcagaag gatgccagct tagagcgtac ttatgcagat
    14161 atcaaacgtg tacttccaaa aaatacctgg gagaacctaa acaaagccaa agagcttggt
    14221 attactccta ccgaatctgc ttacaaaacc tgtaatgatg aattatacgg tgcataaaag
    14281 cattcggtta taatatctgc cgcagggcgg ccggcagaaa actctccaaa ataattacca
    14341 gccgcccgcc agttatcttc ttttttatta gttaaatact acaggaaaag cagagttcac
    14401 aggtaacaaa aatttctcct attgtgttaa ttagaaaaag ttctgtatat gaaaagagtg
    14461 attactatga atgctaaatc gaaagtcaat atattagcaa ttgccaccgt tatcctctgg
    14521 gcctctgctt ttccattttc aaaagttgct atggagcact tttcacctaa ttccttagga
    14581 tgtctgcgta tcaccgcagc ttccatattt cttattctgc tgggaatatt cagccgactg
    14641 catctgccca ggaaaaaaga tatctacaaa ttcttcctct caggtgcact tggttttacc
    14701 ttatatatgc tgaccttcaa cgtagggata cgaaccttaa cgtcggcaac ctcaagtatc
    14761 atcatggcca tgacaccggt aatgaccgca gtaggcgcac tctttatcta ccgggaaaaa
    14821 ataccggcca taggctggat ctccattgga attgaattca tcggtattct ggtcctcacc
    14881 ttgtgggacg gagtactttc cataaatgtc ggaattctct ggaccctgag tactgccata
    14941 ctcttctgtg ggtataatct ataccagaga aaactgctct cccagggata taccccttta
    15001 gagataacca tattcagtat caccgcagga gcaatcttat tccttccgtt cttgccaaac
    15061 ggaatccatg aaatgtccag agctccgctt tcccatattc tggtggtcat atacctggga
    15121 gtctttccca acgccatagc tgcgttcact tggggaaaag ccttattaat tgccaaaaaa
    15181 acaagcgatg taaccaattt tatgtttgta actccattgc tggctaccat aatgggattt
    15241 gtagttttga gagaatcacc atctgcgggt accattgcag gggggatcat cattcttgtc
    15301 ggacttcgcc tatttcaaaa aaagcaaaag gaggctgtga aaaaacagtc cgaataaaaa
    15361 aagaggattt tcaatacact ttagtggttg aaaatcctct ttttgtggta aaatttatct
    15421 gct
//
