LOCUS       c00045_NZ_QRIH..       23212 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_QRIH01000005.1 [Ruminococcus] torques strain AM22-16
            AM22-16.Scaf5, whole genome shotgun sequence.
ACCESSION   NZ_QRIH01000005
VERSION     NZ_QRIH01000005
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:25:40
            Original ID  :: NZ_QRIH01000005.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 72336
            Orig. end    :: 95548
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23212
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[82336:85548]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13212
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..23212
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23212
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             2113..2757
                     /locus_tag="ctg45_77"
                     /transl_table=11
                     /translation="MMKHTIITIGRQFGSGGHEVGNRLAERLDIPLYDHNLIRMAAQEL
                     RISSEDATQVDETILGRFLTAYIVSTGNYTAFMSGDESGEPLSDLVFNRQSAIIRKLAE
                     KGPGIFVGRCADYILGDYSNCINTFIYAYKDDRIRRIMKLYELNEKQAADKIKKTDRER
                     KLYYEARTGREWGGIESNSMMFNTSLLGIDGAVDALEAIYRKWDAGRDVES"
     CDS             2996..3880
                     /locus_tag="ctg45_78"
                     /transl_table=11
                     /translation="MSFISYLINGISLGSVYAIIALGYTMVYGIAKMLNFAHGDVIMIG
                     AYMALITMMKAGMSPILAIVAAVIVCTVLGILIERIAYKPLRNASSSLAVLITAIGVSY
                     LLQNTALLVFGANAQTFPSVIKWKGLSLAGGKLNISGETIVTIAACVVIMIVLMLFVQK
                     SKPGQAMRAVSEDKGAAQLMGINVNGTIALTFAIGSALAAVAGVLLCSAYPSLTPYTGA
                     MPGIKAFVAAVFGGIGSIPGAFIGGILLGVIEIFGKAYISSQMADAIVFAVLIIVLLVK
                     PTGLLGKKIQEKV"
     CDS             3893..4960
                     /locus_tag="ctg45_79"
                     /transl_table=11
                     /translation="MDKLKNMKKTTKNNIITYALVIAAFVIMQSLINAGSISSLLEGLM
                     VPLCIYIIMAVSLNLVVGVLGELSLGHAGFMCVGAFASAFFSKCMRDTIESASLRFFLA
                     LLIGIAAAAIFGILIGIPVLRLKGDYLAIVTLAFGEIIKNLVNVLYIGKDSNGFHFSTK
                     DVMALNMEPDGKVIINGPQGITGTPKDATFFIGFILILITLFIVLNLIHSRDGRAIMAI
                     RDNRIAAESVGINITKYKLMAFTISAAMAGAAGVLYAHNLSTLTANTNNFGYNMSIMIL
                     VFVVLGGIGNIRGSIIAAVILTLLPEMLRGLSDYRMLIYAIVLIVMMLFNWAPKAIEWR
                     EKYLSFGKKKKEAVK"
     CDS             4960..5718
                     /locus_tag="ctg45_80"
                     /transl_table=11
                     /translation="MALLEVKNLGISFGGLRAVNGFDISIEKEALYGLIGPNGAGKTTV
                     FNLLTGVYKPDSGKVLLDGTDITGKNTIEINKAGIARTFQNIRLFKQLSVLDNVKVGLH
                     NKHHYSTLSGVLRLPGYRKVEKEMDEQAMELLKVFNLEDVAHVAASNLPYGQQRRLEIA
                     RAMATEPKLLLLDEPAAGMNPNETGELMDMIRFVREKFHMTILLIEHDMKLVSGICEKL
                     TVLNFGEVLCEGKTSDVLNDPQVVTAYLGE"
     CDS             5730..6440
                     /locus_tag="ctg45_81"
                     /transl_table=11
                     /translation="MAMLEVKDLQVYYGMIQAIKGISFEVNQGEVIALIGANGAGKTTT
                     LHTVTGLISPKSGQVLFEGKDITKTPAHKIVSMGMAHVPEGRRVFAELSVYENLRMGAY
                     TRKDKAEIEETLKSVYKRFPRLQERKNQMAGTLSGGEQQMLAMGRALMSKPRIILMDEP
                     SMGLSPIMVNEIFDIIRAVSESGTTVLLVEQNAKKALSIADRAYVLETGKIVLSGDAKE
                     LLEDDSIKKAYLGE"
     CDS             6456..7085
                     /locus_tag="ctg45_82"
                     /transl_table=11
                     /translation="MRNIVITISRQYGSGGKTIGAMLAKELGINCYSREILRMASEDSG
                     INEKLFGMSDEKVRRAGWFKLLSRPYEGGLIPPEDREFTSDDNLFNYQAKVIKELAAKE
                     SCVIVGRCADYVLKDYPNVVSVFVHADRKFCLDRSMERHSMTEKEMQKYIEKTDQYRGD
                     FYRYHTGHEWVDARNYDLCLNSGKLGFEKCVEEIKAYIKVRFGETL"
     CDS             complement(7113..7607)
                     /locus_tag="ctg45_83"
                     /transl_table=11
                     /translation="MRIRKATQQDLHSIMQLYENARAFMREHGNPGQWGTTYPPQNMIE
                     TDIRFGNLYVCIEKDTIEAVFFYKDGIDPTYLKIYDGQWKNDAPYGVVHRITSSGKVKG
                     AASFCLDWAFSQCGNLKIDTHENNIVMQNMLKKNGFTYCGRIYIDNGGERLAFQKDSPV
                     P"
     CDS             7898..8389
                     /locus_tag="ctg45_84"
                     /transl_table=11
                     /translation="MEGIRMYKEKQKVGFGMNYTQSRELKENNRIYREMESIYHEICVK
                     AGISDTDFIVLYSIVEFEDGCCQRKIAKQYSISRQTVNSSVKKLVQNGCVVLESGKGHD
                     KQIVLTEKGKAMAKQKIIPVMEAEAGVFMHMTEEERKKLLRLNAKYMEIFRQKVGELRL
                     "
     CDS             8386..9717
                     /locus_tag="ctg45_85"
                     /transl_table=11
                     /translation="MNIQLSDHFTYRRLIRFTISTVLMLICTSMYSIVDGLFVSNYVGK
                     MPFAATNLIWPVSMGIAAIGFMLGTGGSAIVAKTLGEGKKEKANQYFSMILYFGIIVSV
                     IFSVICFIFTPQIARMLKADGELLEHCIVYGRILFATQTAFILQNMFQSFLVAAEEPVL
                     SLKINIAAGLTNVVFDYLFIAVFEWGVAGAAIATGMGQIVGGIAPFFFFAKGSRNGLRI
                     TWRTKLYKDILLKTCMNGSSEMVTNLSTSLVNILYNFQLMKLAGADGVAAFGVIMYVNF
                     IFVAVFMGYSVGSAPIVSYHYGAGNDAELHNLYRKSKNILIVAGIVLTIAAEILSMPLV
                     RIFVNYDKELLLMTVRGFRLFSFSFLIMGINIWASSFFTALNNGFVSAAISFLRTFLFQ
                     VAAVCFLPLIIGIDGVWTSVLAAETMALAVTIIFLIKEKKKYRY"
     CDS             10001..12253
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_86"
                     /sec_met_domain="Gly_radical (E-value: 1e-39, bitscore:
                     128.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.4e-273, bitscore:
                     900.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQFDQWAGFSGKNWKNSVDVRDFIQENYTPYDGDESFLEGPTEA
                     TDKLWGRLQELQKEERAKGGVLDMETEVVSGLTAYGPGYIDESMKDLEKVVGLQTDKPL
                     KRAFMPYGGINMAVKACTTYGYEPNERLKEIFTKYHKTHNQGVFDIYTPEMKKARHNKI
                     ITGLPDTYGRGRIVGDYRRVALYGIDFLIEKKQYDFERYARHGMKGTDFRLREEIADQI
                     RALQQMKEMAAIYGYDISQPAKDAKEAVQWLYFGYLAAIKTQNGAAMSVGRISTFLDIY
                     IERDMKNGVLTESEAQELIDHMVMKFRMVKFARIPSYNELFSGDPVWATLEMGGLGQDG
                     RSMVTKNDFRFLHTLENMGPSPEPNLTVLYSERLPENFKKYTSLISVKTSSVQYENDDV
                     MRPVWGDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGVDEKTKVQVAPAYRP
                     ITSEYLDYDEVMEKYDEMMEWLSKLYVDTLNMIHYMHDKYYYEAAEMALIDTDVRRTFA
                     TGIAGFSHVVDSLSAIKYAKVKVIRDEDGLATDFEIEGDFPRYGNDDDRADDIAIWLLK
                     TFMHKLSKCHTYRDSEPTTSILTITSNVVYGKATGTLPDGRKAGEPLSPGANPSYGAEK
                     NGLLASLNSVAKLPYELALDGISNTQTISPNALGHDDDERKVNLARVMDGYFHQGAHHL
                     NVNVFGTDKLIDAMEHPEKPEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHESM"
     CDS             12460..13212
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 79.9;
                     E-value: 7.2e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_87"
                     /sec_met_domain="Radical_SAM (E-value: 2.3e-31, bitscore:
                     102.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQANEIKGYVHSLESFGSVDGPGVRYVIFLTGCAMRCQFCHNPD
                     TWNLKKGTLYTADELLKTALRYRTYWGDKGGITVSGGEPLLQIDFLIELFRKAKEAGVH
                     TTLDTSGNPFTREEPFFGKVQELMKYTDLVMLDIKHIDDEQHKILTGCTNENILDFAKY
                     LDEIKKPVWIRHVLVPQRSDDDGALGKLREFIDGLSNVEKVEVLPYHTLGAYKWKELGY
                     EYPLEGIDPPTKERIENANKILRTAECK"
     CDS             complement(13288..14628)
                     /locus_tag="ctg45_88"
                     /transl_table=11
                     /translation="MNAARQNEQSIFHTFFKYVSSNVLGMIGFSCYILADVFFIARGIG
                     ADALAALNLTLPAYNLMNGIGLMIGMGGAARYSLSSTRPDSDTHRTAFTHALLLAALCA
                     LFFSFAGAFCSEEISAILGADHDTIGYASDYIRILLLFSPLFLGNNLLLCFVRNDGAPR
                     LSMAGMLIGSLANIVLDYIFIYPLGMEMAGAATATATAPVISMLIMSVHFIKKNNRFHI
                     TKIRLSLKRAADICFLGVSSLVLELSSGIVIIVFNFLILKLNGNTGVAAYGILANIALV
                     LTSVFTGIAQGIQPIVSRHADAKGKHVQNSIRKYALITSLLLSLVSYITISLFSVPIAE
                     AFNKADDPLLTTIASGGMRIYFINLFFAGVNIIASAFLCSCDKPKLAFVISVLRGFILI
                     IPAAWILSSLFGLTGIWLTVPVTEAIVCLFSFLFLFRGTHTQIVQST"
     CDS             14960..16123
                     /locus_tag="ctg45_89"
                     /transl_table=11
                     /translation="MNKKEILEIRKQFTPANCAITRICGCYVDHEKEKKMESKEAFLSL
                     PEEEAFKYFDIFKKTLSGTVGKNILNMEFPIDAEMPGGTQEFLLKLRSSKLQDDMLLEE
                     FYDKVIEAYDCAENYYIILIHAMYDVPGKSSDGIEMFDASDEVYEYLLMSLCPVSLSKA
                     GLSYNAESNCIQDRIRDWIVDMPDKGFLFPAFNDRSTDLHSMLYYTKKSEDLQPGMIDQ
                     LFGTKMPMSADTQKETFKMLIEDTLGEDGDYETVRNIHETLNQLIEEHKEEPEPLALDL
                     TDMKKVFEQSGVEAEKMESFDRNFTENAGEKTSLLASNIAETRKFQIETPDIVIKVNPE
                     RADLVETRIIDGRRCLVIPVDDHIEVNGINVQTIKMKEREENQETYN"
     CDS             16260..16715
                     /locus_tag="ctg45_90"
                     /transl_table=11
                     /translation="MFQCDINDAPVIGILGIVSHRAKVAAKDMYSVFDLNRSQASILLT
                     LHHCESMSQKDLAKQLNITAPSITSSIRKMEQFGYIARQTDPADQRVMRLALTEKGRSC
                     IQSIKDVTDKMEEILLKGMSVEEKILFRRLLVHVNNNIDQYERKEKI"
     CDS             16712..19036
                     /locus_tag="ctg45_91"
                     /transl_table=11
                     /translation="MKNLFKYASEHWKALLAIVAILIVQAYCDLSLPAYTSDIVNVGIQ
                     QGGVEDHIPDAISAEDMETLLLFTSEKDGKTVLSAYEKDDKTYEEQAYVLKDTVKEDTD
                     RTEKLSGILAAPMMMAAGFESGSDMTADIEEQLKAQLPPEMISEDMTVLDILKMMPQEQ
                     KQAFVSEIEKKTEELPDTITEQAAVNYVKEAYADLGIDMDELQFRYLFSTGAKMIGLAF
                     LGMVASVLVGFLASRVGAAAGRDLRGRVFKKVVGYSSNEFDHFSTASLITRSTNDIQQV
                     QFIIVMLLRIVLYAPILAIGGIVQVFQTNVSMSWIIGLAVVLIALVVLVLFAVAMPKFK
                     SLQKLVDKVNLVMREILTGLPVIRAFSTEKHEEKRFDKANMDLMKTNLFVNRAMTFMMP
                     IMMLIMNGISVLIMWSGAKGINDGQMQVGDMMAFIQYTMQIIMGFLMICMLSVMLPRAA
                     VAADRVDEVLSSRTVIHDPKTPKKFEEKQKGVLTFDHVSFKYPGADENVLEDITFTAKP
                     GETTAIIGSTGSGKSTLVNLIPRFYDVTDGSIRLDGTDIREVTQHDLRDKLGYVPQKGL
                     LFSGDIASNIMFGNPEGGGQEMKEAAQIAQATEFIEAKPNKYESPISQGGSNVSGGQKQ
                     RLSIARAIAKRPEVFIFDDSFSALDFKTDVALRKALKKRTKESTVLIVAQRISTILNAE
                     QIIVLDDGKIAGIGTHKELLRNCEVYKQIAASQLSEKELQDGMQSEDRKTEDIKSETIK
                     TEERKEAISAKTAEQEVRSDV"
     CDS             19029..20864
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     289.1; E-value: 4e-88)"
                     /gene_kind="resistance"
                     /locus_tag="ctg45_92"
                     /transl_table=11
                     /translation="MSRHGMKGPHGGMRGGAKAKDFKGSLKKLVKYMSVYKVQMLFVAV
                     FAVCGTVFNIVGPKILGKATTEIFNGLVSKVSGGSGMDFGKIGQILLITLGLYVVSALC
                     SFIQGMIMTGISQKTTYRLRKDITEKVNRMPMDYFDTKPVGEVLSRVTNDVDTLGQSLN
                     QSATQLITSVTTLIGVLVMMLSISPLMTVVALLILPISVGLISFVMKHSQKYFSGQQEY
                     LGNVNGQVEEVYSGHNVIKAFNKEDDVIREFDRTNDKLYESAWKSQFFSGMMMPVMQFV
                     GNLGYVGVAILGGFLAIKKTIEVGDIQSFIQYVRNFTQPIQQVAQVTNMLQLAAASSER
                     VFEFLEEKEEDQTVEHPVSVEGLHGNVQFENVHFGYNPEKIIINDFSANVKEGQKIAIV
                     GPTGAGKTTMIKLLMRFYDVNSGSIKIDGHDVRDFNRSELREMFGMVLQDTWLFHGTIM
                     DNIRYGKLDATEEEVIQAAKAAHVHRFVQTLPGGYQMEINEEATNISQGQKQLLTIARA
                     ILADPKILILDEATSSVDTRTEVRIQKAMDNLMKGRTSFVIAHRLSTIRDADLILVMKD
                     GDIIEQGTHTQLLAQNGFYAELYNSQFESTDQTCA"
     CDS             21482..22381
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     68.9; E-value: 8.9e-22)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg45_93"
                     /sec_met_domain="LysR_substrate (E-value: 5.2e-17,
                     bitscore: 54.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.7e-21, bitscore: 68.9,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKKSFYFFMSVVETGSFSQAAKKHYLSQAAISQQISKLEEEVGV
                     RLFDRSKYRPELTEAGKYYYQKIKQLSEEYEKIEKQTRYIQKKNSQKIVVGITGPFENK
                     YLPRIINEYKEGHETHFDVRVYTFEEGKKLLEAGDIDIAFGLSSEFSVNPDISYETIHQ
                     SETCIVCSRKNRLSQYKSINPILVKDEPMITLSSQMGRKFYDDFMKAFILDGFEPNIVK
                     EVNSLSEYFISIKLDEGIGYTGREVVPEEEDLCTVKIVGSHHHADFAVAYLKENKKQSV
                     VQFYEYIVAYFKDYKKNL"
ORIGIN
        1 aagtaaagaa ctggcgtcta tccggggcgg ggaaatgctt cagggactgc tctctatggg
       61 agtgtttgta gttgcggtat tcgcattgat ctttctgtat tatacgaact cgtttcttat
      121 aaggaaaagg aagaaagaac ttggattata taatattctc gggatgggca aacgtaatct
      181 ggtaagaatt cttttgtggg aaaatatact gactgccgtg atttctctgg ttatcggaat
      241 cgtgttcgga attctgttct caaaacttgc ggaacttctg gcaattaagc ttcttgacgg
      301 ggcgaccgga ttcggagttc atatagaaat gaagccgatc cttatgacag tcggtctgtt
      361 tcttgcgatc tttctgctta ttatgatccg catgcttgtg tcggtatata aacttcgtcc
      421 gattgagatg ctcagaagtg agaatgtcgg cgaaaaaccg ccgaaggcaa actggctctt
      481 tgcatttgcg ggagcggtga tccttgccgg agcatattat ctggctgtga agatcatcga
      541 tccgacaact gcgatgcttg tattctttct cgcggttgtt atggtgatca ttgccacata
      601 ccttctgttt attgcaggtt cggtcgctct ttgcaagctg ctgcaaaaga gcaaaaagta
      661 ttattataag acgagacact ttgtatcttt gtcacagatg gtttaccgaa tgaagagaaa
      721 cggagcgggt ctggcgtcga tctgtatttt atctacgatg gtgcttgtga cgatctcgtc
      781 tacgatgtgt atttatgcag atacggaatc gtcgatcaga aaccgttatc cacatgacat
      841 cacgatcgag tggagcggga aaacatccct tccgcaaaat gaggacggaa cagatacaga
      901 attaaaagac agcgtagtgc agcgtttgac gccggagatg accatgacgt ataaagaggc
      961 tgtggaaaag gtgcttgaat ctcataaagt aaaggctgag aacttggaaa attataatct
     1021 ttactctctt tccggagtac agtcagacga tgttttaagt attgattttg aaaagatgaa
     1081 aggggagatt tcctcgatta atgcagggat gtcaggatct gtgaagacga tgtattttac
     1141 aacaatggat gattacaaca aactgaaagg cacagacaag actttggctg aagatgagat
     1201 gatgctctac tcatataaaa cagattatga gtatgattcc tttacgatcg acggcgtcgg
     1261 aacatggaaa gtagagacaa tgaaagaacc tccgataggg gtaggcaacg ccatggcgaa
     1321 tatgcagggg tcatatcagg ttgttgtaaa agatttgtct gtgatcgaaa aaatagcgac
     1381 tgcgtacgaa acgatcaatg caaaaccttt gcaggacgga acattgtacc tgctttccct
     1441 gaaagaatgt tatgactttg atctgaaatg tgatgaagaa aaacagatag agatttacaa
     1501 ggatattttg gaatcttttg agcatatatc cgaagcggca gatgaacagg gcaatcggat
     1561 gggagattcg ctggcaaatt attatgcgga cagtaaagcg tacggtaaag gagatttcat
     1621 tgcgctcaac ggcggattgt ttttcctcgg agtgcttctc ggagcggtat tcctgttcgg
     1681 tactgtgctg attatgtact acaagcagat ttccgaagga tatgaagatc aggatcgctt
     1741 taatattctt atgaaagtgg gaatgacaaa gaaagaagtg aagcagacga tcaactctca
     1801 ggtgcttact gtatttttca tgcctctgat catggcggga attcatcttg cgtttgcatt
     1861 tccgatgatt cagaaaatac tgatgcttat gtcaggcgtg gaagcgaaag tatttgtgat
     1921 cgtgacgatc ggatgttatc tcgtgtttgc actcttctat gtacttgttt atgtcgtaac
     1981 gtcaaaaagc tattatacga tcataagcag taaggaaaaa tagaaaaaat caataaattt
     2041 ctattcatac ccgggaaaca atgttatact tgagtatatc aatacagcga tccgcagaga
     2101 ggagtggcac atatgatgaa acacacgatt atcacgatcg gaaggcaatt cggaagcggc
     2161 gggcatgaag taggaaatcg attggcagaa cggcttgaca ttccgcttta cgatcataat
     2221 ctgatccgca tggcggcgca ggagcttcgg atcagcagtg aagatgcgac gcaggtagac
     2281 gagacgattc tcggaagatt tctcacggca tatatagtca gtacaggaaa ctatactgca
     2341 tttatgagcg gagacgagtc gggagaacct ctaagtgatc tcgtctttaa caggcagtcg
     2401 gcgatcataa ggaaacttgc ggagaaaggt ccgggaattt ttgtcggaag atgtgcggat
     2461 tatatcctcg gagattattc aaactgcatc aatacgttta tttatgcata taaggacgat
     2521 cgtatccgca gaatcatgaa gctttatgaa ctaaacgaaa agcaggcggc agataagatc
     2581 aaaaagacag accgcgaaag gaagctttat tatgaggcaa ggaccggccg cgaatggggt
     2641 ggaatcgagt cgaacagcat gatgtttaat acgagtcttt tagggatcga cggagcggtg
     2701 gatgctctcg aagctattta ccgcaaatgg gatgccggga gagacgtcga gtcataaaat
     2761 gccggcatat atgtaaaatg aatgacacgt catgcagggg agtttttatt tcggaagaaa
     2821 aagccggata gatacaaaat aaagcagtta aaaacgggta cgtgaaaaaa accgagcgta
     2881 ctcgtttttt cttattgata atcctatatt ttttgtggta taatccttat taatcatgat
     2941 aaacagagaa gagatcgttt atcggaacaa taagagaaat gaaagggaat gagacatgag
     3001 ttttatatcg tatttgatta atggaatcag tcttggaagt gtctatgcga tcatagcgct
     3061 tgggtatacg atggtttatg ggattgcgaa gatgctgaac ttcgcccatg gcgacgttat
     3121 tatgatcggt gcgtatatgg cgctgatcac gatgatgaag gcggggatgt cgccgatcct
     3181 tgcgatcgtt gccgctgtaa tcgtgtgtac ggtactcgga atcttgatcg aacgtatcgc
     3241 gtacaaaccg ctgcgtaacg catcgtcttc acttgccgta ttgatcacgg cgatcggcgt
     3301 aagctacctt ctccagaata cggcgcttct cgtattcggg gcgaacgcac agacgtttcc
     3361 gtcggttatt aagtggaaag gtttgtcttt ggcaggcggc aagctgaaca tttcagggga
     3421 gacgatcgtg acgatcgcgg catgtgtagt gatcatgatc gtactgatgc tgttcgtgca
     3481 gaaatcaaag ccgggtcagg caatgcgcgc tgtatcggaa gataaaggcg cggctcagct
     3541 tatgggaatc aatgtaaacg gaacgatcgc tcttacgttt gcaatcgggt cggcgctggc
     3601 ggctgttgca ggtgtgcttt tgtgttcggc atatccgagc ctgacgccgt atacaggagc
     3661 gatgccgggt attaaggcgt tcgtagcggc tgtatttgga ggaataggtt cgataccggg
     3721 agcgtttatc ggaggaattc tgctcggtgt gatcgagatt ttcggaaaag catacatttc
     3781 gtcacagatg gcggatgcga tcgtattcgc ggtacttatc attgtgcttc ttgtgaaacc
     3841 tacaggtttg ttaggtaaga aaattcaaga gaaagtgtag gtgatcagag cgatggataa
     3901 attaaaaaat atgaaaaaaa ctacaaaaaa taatatcatc acatatgctc ttgttatcgc
     3961 ggcatttgtg atcatgcagt cactgatcaa cgccggaagt atttccagcc ttcttgaagg
     4021 attgatggtt ccgctttgta tttatattat tatggctgtg tcgctgaacc tcgtagtcgg
     4081 cgtacttgga gaattgagcc tcggacatgc gggctttatg tgtgtcggcg cgtttgcaag
     4141 tgcattcttt tcaaaatgca tgagagatac gatcgaatcg gcttcactgc gcttctttct
     4201 ggctcttttg atcggaattg cggctgctgc gatcttcggc attctgatcg gaattccggt
     4261 tctgcgtctg aaaggcgact atctggcgat cgtgacattg gcattcggag agatcattaa
     4321 aaacctcgta aacgtattgt atataggtaa agattccaac ggttttcatt tttcgacaaa
     4381 agatgtgatg gcgctgaata tggaaccgga cggaaaggtt atcattaacg gtccgcaggg
     4441 gattacggga acgccgaaag atgcgacgtt ttttatcgga tttatactga ttctgattac
     4501 gttgtttatc gtgcttaatc tgatccattc aagagacgga cgcgcgatca tggcgatccg
     4561 tgacaaccgt atcgcggcgg aatcagtcgg tattaatatt acaaaatata aactgatggc
     4621 gtttacgata tctgcggcga tggcaggagc ggcaggcgtg ctttacgctc acaatctgtc
     4681 tacgctgacg gcgaatacaa acaacttcgg ttataatatg tcgatcatga tccttgtctt
     4741 tgtcgttttg ggcggtatcg gaaatatcag aggttcgatc atagcggcag tgatcctgac
     4801 acttcttccg gagatgctcc gtggattgtc agattaccgt atgctgatct atgcgatcgt
     4861 tctcattgtc atgatgctct ttaactgggc gccgaaagcg atcgagtgga gagaaaaata
     4921 tctttctttc ggaaagaaga aaaaggaggc tgtaaaataa tggcgttact ggaagttaaa
     4981 aatctcggga tttcatttgg cggtctccgt gcggtaaacg ggtttgacat ttcgattgaa
     5041 aaagaagctc tgtacggact gatcggtccg aacggcgcgg gaaagacgac tgtattcaac
     5101 cttcttacag gagtatataa gccggacagc ggaaaagtgc tgctggacgg aacggatatt
     5161 acagggaaaa acacgattga gatcaataag gcgggaatcg cccgtacatt tcagaatatc
     5221 cggctgttta agcagttaag tgttcttgat aacgtgaaag taggacttca caataaacat
     5281 cattattcta ctctttcggg agtcttaaga cttcccggtt acagaaaagt ggaaaaagag
     5341 atggatgagc aggcaatgga acttttgaaa gtgttcaatc tggaagatgt ggcgcatgtt
     5401 gccgcctcta atcttccgta cggacagcaa agaaggcttg agatcgccag agcgatggcg
     5461 acagaaccga agcttttgct gctcgacgag cccgctgcgg gcatgaaccc gaacgagacg
     5521 ggggaattga tggacatgat ccgttttgtg agagaaaaat tccatatgac gatccttttg
     5581 atcgaacatg atatgaaact ggtaagcggc atttgcgaga agttgacggt gctcaacttc
     5641 ggagaggtgc tctgtgaagg taaaacgtcg gatgttttga acgatccgca ggttgttacc
     5701 gcatatcttg gagaataggg ggaatcgtta tggcaatgct cgaagtaaaa gatttacaag
     5761 tatattatgg tatgatccag gcgatcaaag gcatttcttt tgaagtaaat caaggagagg
     5821 tcatcgcttt gatcggagca aacggcgcgg gaaagacgac gacgctgcat acagttacag
     5881 gtctgatctc cccgaagagc ggacaggtgc tgtttgaagg aaaagatatt acaaaaactc
     5941 cggctcataa gatcgtctct atggggatgg cgcatgtacc ggaaggaaga agagtgttcg
     6001 cagaattaag cgtttatgag aatttgagaa tgggcgctta tacacgaaaa gataaggcgg
     6061 agattgaaga aacattaaaa agtgtctata agcgttttcc gcgtttgcag gaacgtaaaa
     6121 accagatggc gggaacatta agcggcggcg aacagcagat gctcgctatg gggcgcgcgc
     6181 ttatgtccaa accgaggatt attttaatgg atgaaccgtc gatgggactt tctccgatca
     6241 tggtaaatga aatctttgat attatccgtg cggtgagcga aagcggaacg acagtccttc
     6301 ttgtagaaca gaatgcgaag aaagctcttt cgatcgccga cagagcatat gtgttggaga
     6361 caggaaagat cgtcctttcg ggagatgcaa aagaacttct ggaagatgat tcgattaaaa
     6421 aggcttatct cggagagtaa aggaggcgtg ttttaatgag aaatatcgtc atcacaattt
     6481 caagacagta cggaagcgga gggaaaacga tcggggcgat gcttgcaaaa gaacttggca
     6541 tcaactgcta cagcagagag atccttcgta tggcttccga ggacagcgga atcaatgaaa
     6601 aactgtttgg tatgtcggac gaaaaggtgc gcagggcagg atggtttaag cttttgagcc
     6661 gtccgtatga gggcggattg atcccgccgg aagacagaga gtttacttcg gacgataacc
     6721 tgttcaatta tcaggcaaag gtgatcaaag agcttgcggc aaaagagtcg tgcgttattg
     6781 tcggaagatg cgcagattat gttttaaaag attatccgaa tgtagtcagc gtattcgtgc
     6841 atgcagacag aaagttctgt ctggatcgtt caatggaacg tcacagcatg acggaaaaag
     6901 agatgcagaa atatattgag aaaacagatc agtacagagg tgatttttac agataccata
     6961 caggtcatga atgggtcgat gcaagaaatt acgatctgtg tctgaacagt ggaaaactcg
     7021 gatttgagaa atgcgtagaa gagatcaaag cgtatataaa agtacggttt ggcgaaacct
     7081 tataacttaa aagaatagct tcaagagact cctcagggta ctggggagtc tttttggaat
     7141 gcaagccgtt cgccgccatt gtctatatag atgcgtccgc agtaagtaaa tccgtttttc
     7201 ttcagcatat tctgcataac gatattgttt tcgtgcgtat cgatctttaa atttccacat
     7261 tgtgaaaatg cccagtcaag acaaaaagag gctgcgccct ttactttgcc ggatgaagtg
     7321 atccggtgga caacgccgta gggagcatcg tttttccatt gtccgtcata aattttcaga
     7381 taggtcggat ctatgccgtc tttatagaag aaaacggctt cgatagtatc tttttcgatg
     7441 cagacgtata aattcccgaa gcggatatct gtttcaatca tgttttgagg aggatacgtc
     7501 gtcccccatt ggccggggtt tccgtgttcg cgcatgaatg cgcgggcgtt ttcatataac
     7561 tgcataatag aatgtaaatc ttgttgtgtt gcttttcgga tacgcataat aaaagtcctt
     7621 tctttcttat aaaaagcgct gacgcctgct ttgtatttta ttattcaaat attctcatgt
     7681 ttttggcgct tcttgttcaa gatgttttgt gttctggcag acttataata atattatgtc
     7741 ataatgtttc ctctttctca acagaaaaac agttattttt agtggacctc atggtaaaga
     7801 catcatagat gaatggttga atttaatctg aaatcggatt ataattaaac gagaaaaatc
     7861 cgatttcgga tttttgaaag gagggaagga taaaagtatg gaaggtataa gaatgtataa
     7921 agaaaaacag aaagtggggt ttggcatgaa ttatacgcag tcgagagaat taaaagagaa
     7981 caacaggatc tatcgggaga tggagagtat ctaccatgaa atatgtgtaa aagcgggaat
     8041 atcggacact gactttattg tgctgtatag tatcgtagag tttgaagacg gttgctgcca
     8101 gaggaaaatc gcaaaacagt attctatcag tcggcagaca gtgaattctt cggtgaaaaa
     8161 attagtgcaa aacggctgcg ttgtattgga aagcggcaaa gggcatgaca agcagattgt
     8221 tttgaccgaa aaaggaaaag cgatggcaaa acaaaagatc attcccgtga tggaggcaga
     8281 ggcaggcgtt tttatgcata tgacagaaga ggagagaaag aaacttttac gtttgaatgc
     8341 aaaatatatg gaaattttca gacaaaaggt aggagaatta agattatgaa catacagctt
     8401 tcggatcact ttacataccg cagactgatt cgctttacaa tatcaacagt tcttatgctt
     8461 atctgtacgt cgatgtacag tattgtagac ggactttttg tgtcaaacta tgtcgggaaa
     8521 atgccatttg cggcgacaaa tctgatctgg ccggtatcta tgggaatcgc agcaatcgga
     8581 tttatgctcg gaacaggcgg aagcgccatc gtagcaaaaa cgcttgggga aggtaagaag
     8641 gaaaaagcga atcaatattt ttcgatgatt ctttatttcg gtattatcgt cagcgttatt
     8701 ttttcggtta tctgttttat ctttacgccg caaattgccc ggatgctcaa agcggatggc
     8761 gaacttttgg aacattgcat cgtatacgga agaattcttt ttgcgacgca gacggcgttt
     8821 attttgcaga atatgtttca aagctttctc gttgccgcgg aagagccggt tttgagcctg
     8881 aagatcaata ttgcggccgg actgacgaac gttgtgtttg attacttgtt tatcgcagta
     8941 tttgagtggg gagtggcagg agctgcgatc gctacaggaa tgggacagat cgtaggaggg
     9001 atcgcgccgt ttttcttttt tgcgaaagga agccgcaatg ggctgcggat cacttggaga
     9061 acgaaactgt ataaagatat tcttctgaaa acatgcatga acggttcgtc ggaaatggtg
     9121 acgaatttgt cgacgtctct tgtgaatatt ctttataact ttcagttgat gaaacttgca
     9181 ggtgcagacg gtgtggctgc gtttggagtc attatgtatg tgaattttat cttcgttgcg
     9241 gtttttatgg gatattcggt cggaagcgct ccgattgtaa gttatcatta cggagcgggg
     9301 aatgacgcag agcttcataa tttatacagg aaaagtaaaa atattttgat tgtagcggga
     9361 attgtactga cgatagcggc ggagatactt tcaatgcctc ttgtcaggat ttttgtaaat
     9421 tatgataaag agcttctttt gatgaccgtt cgcggattcc gcctgttttc tttttcgttc
     9481 ttgattatgg gaatcaacat atgggcgtct tctttcttta cggcattgaa taacggattt
     9541 gtgtcggcgg ctatttcgtt tttgagaacg tttttgtttc aggtggcggc agtatgtttc
     9601 cttcctctga ttatcggtat cgacggagtg tggacgtccg ttttggctgc agaaacgatg
     9661 gctttggcgg tgacaattat atttttaata aaggagaaga aaaagtaccg ctactgaaag
     9721 tatgataatg atttaacaaa cacaatatat agtaaatata agagcgtata caggcaaaat
     9781 tgtactaaat caagaacaaa ggcatttttg agaaggattc tcgttataat ggttgttttt
     9841 tccttcgggt gatgttatac tagcgcatgt ggcaatgaga tacaaattac gatatcattt
     9901 ggactgttta accgctcatt gcatgaaccg aaagcgcaga tgatgtgctt cggtatgaaa
     9961 cgaataaatt tattaagatt tcagaggagg ctttcaaatt atggcacaat ttgatcagtg
    10021 ggcaggattt tccggaaaga actggaaaaa ttctgtagat gtacgcgatt tcattcagga
    10081 gaactacaca ccgtatgacg gagacgaatc attcctggaa ggacctacag aggcaacaga
    10141 taaactgtgg ggaagacttc aggagctgca gaaagaggaa cgtgcaaaag gcggcgttct
    10201 tgacatggag acagaagttg tatccggtct tacagcatac ggcccgggat atatcgacga
    10261 gagcatgaaa gacctggaga aagttgtcgg acttcagaca gacaaaccgc ttaagagagc
    10321 gtttatgcct tacggtggta tcaacatggc agtaaaggct tgtacaactt acggttatga
    10381 gccgaatgaa agattgaaag agatctttac aaaatatcat aaaacacata accagggagt
    10441 attcgacatc tacacaccgg agatgaagaa agcccgtcac aacaagatca tcacaggact
    10501 tccggataca tacggacgcg gacgtatcgt aggcgactac cgtcgtgttg ctctgtacgg
    10561 tattgatttc ctgatcgaga aaaaacagta cgacttcgag cgttatgcaa gacacggcat
    10621 gaaaggaaca gacttccgtc ttcgtgaaga gatcgcagat cagattcgcg cacttcagca
    10681 gatgaaagag atggcagcaa tctacggata tgatatttca cagccggcaa aagatgcaaa
    10741 agaagcagta cagtggctgt atttcggata ccttgcggcg atcaagacac agaacggagc
    10801 tgcaatgagt gtcggacgta tctctacatt ccttgatatt tatattgaaa gagatatgaa
    10861 gaacggtgtt ctgacagaga gcgaagctca ggaattgatc gaccacatgg ttatgaagtt
    10921 ccgtatggtt aaattcgcaa gaatcccgtc atacaacgag ctgttctcag gagacccggt
    10981 atgggcaaca cttgaaatgg gtggtctcgg acaggacgga cgttctatgg taacaaagaa
    11041 cgacttccgt ttccttcaca cacttgagaa catgggaccg tctccggagc cgaacctgac
    11101 agttctttac tcagaaagac ttccggaaaa cttcaagaaa tatacatctt tgatttctgt
    11161 aaagacaagt tccgtacagt acgaaaacga tgatgttatg cgtccggttt ggggcgatga
    11221 ctacagcatc tgctgctgtg tatccgcaac tcagacaggt aaagagatcc agttcttcgg
    11281 agcaagagca aaccttgcaa aatgcctgct ttacgcgatc aacggcggtg ttgacgagaa
    11341 aacaaaagta caagtagctc cggcttacag accaatcaca tcagagtatc ttgattacga
    11401 tgaagtaatg gagaaatatg acgagatgat ggagtggctg tccaaactgt atgttgatac
    11461 attgaacatg atccactaca tgcatgacaa atactactat gaagcagcag agatggctct
    11521 tatcgataca gatgtaagac gtacatttgc aacaggtatc gcaggattct cacatgtagt
    11581 agactcctta agcgcaatca aatatgcgaa agtaaaagta attcgtgacg aagacggtct
    11641 tgcaacagac tttgagatcg agggagactt cccgagatac ggtaacgatg acgaccgtgc
    11701 agacgatatt gcgatctggc tgctcaagac atttatgcac aaattgagca aatgccacac
    11761 atacagagat tctgagccta caacatcgat cctgacaatt acatcaaacg tagtttacgg
    11821 aaaagcaaca ggaactcttc cggatggaag aaaagcaggc gagccgctgt caccgggagc
    11881 aaacccgtct tacggcgcag agaagaacgg tcttcttgct tccctgaact ctgtagcaaa
    11941 acttccgtac gagctggctc ttgacggaat ctctaataca cagacgatca gcccgaatgc
    12001 actcggacat gatgatgacg agcgtaaagt aaatcttgcc cgcgtaatgg acggatactt
    12061 ccatcaggga gcacaccacc tgaacgtaaa cgtattcggt acagataaac tgatcgacgc
    12121 tatggagcac ccggaaaaac cggaatatgc aaactttaca atccgtgtat caggatatgc
    12181 cgttaagttt atcgacctga caagagagca gcagttagac gtaatcgcaa gaacttgcca
    12241 cgagtctatg taataaatag taacagttca gtccgcgcca ttcgtaaaac tgcactgtat
    12301 ggctgaactg ttacaataaa taaaggtctg cagatttctt tagaaagaaa aatgtgacta
    12361 taagatgaag aaagtccggt tcttttgctt gagatatgat ctttggcaga agaaccggtt
    12421 tctttataaa tctttataaa atgaaaagga gacgccggaa tggaacaggc aaacgaaata
    12481 aaaggatacg ttcattcact tgaaagtttt ggatcagtag acggaccggg agtacgatac
    12541 gtgatctttt tgacaggatg cgctatgcgc tgtcagttct gtcataaccc ggatacatgg
    12601 aatcttaaga aaggaacgct gtatacggca gatgagcttc tgaaaacagc tctgcgctat
    12661 cgcacttact ggggagataa aggcgggatc acggtaagcg gaggagagcc tcttcttcag
    12721 attgacttct tgattgaatt gttccgcaaa gcgaaggaag ccggagtcca tacaacgctt
    12781 gatacaagtg gaaatccgtt tacgagagaa gaaccgtttt tcgggaaagt acaggaactg
    12841 atgaaatata cagatcttgt gatgctcgat ataaaacata tcgatgatga gcagcataag
    12901 atattaacag gatgtacgaa tgaaaatatt cttgatttcg ctaaatattt ggatgagatt
    12961 aaaaaacctg tctggattcg tcatgtcctt gttccgcaga ggagcgacga tgacggagcg
    13021 cttggaaaac tccgtgaatt cattgacgga ctaagtaatg tggaaaaagt cgaagtcctt
    13081 ccgtatcata cgctcggagc atataaatgg aaagaactcg gatatgagta tccgttggag
    13141 gggattgatc ctccgacaaa agagcggatt gaaaatgcaa ataaaatact gcgtacagcg
    13201 gaatgtaagt aaaaacgaaa gtatcgggat acagaagatg aattttgtat cccgatactt
    13261 tttgatacgc ctgaaagagt gggcgtttta tgttgactgt actatttgag tgtgtgtgcc
    13321 gcgaaaaaga aacaggaatg aaaacaggca tacaatcgct tcggtgacag gaacggtaag
    13381 ccagatccct gtcaatccaa ataatgacga caaaatccat gcggcaggaa tgatcagtat
    13441 aaagcctctt aaaacagaga tgacaaatgc aagttttggt ttgtcgcatg aacataaaaa
    13501 tgcagatgct ataatgttca ctccggcaaa aaataagttg ataaaataaa ttctcatgcc
    13561 tccggaagcg atagttgtca acagaggatc atccgccttg ttgaatgctt cggcgatagg
    13621 aacagaaaaa agactgatcg ttatgtagga aacaagcgaa aggagaaggc ttgtgatcag
    13681 cgcatatttt cgtatactgt tttgtacatg ctttcctttt gcatcggcat gtctgctgac
    13741 gataggctgt atgccctgcg cgatccctgt aaaaacagaa gtgaggacaa gggcgatatt
    13801 tgcaaggatt ccgtaggcgg caacacctgt atttccgttc aacttaagga tcaggaaatt
    13861 gaatacgata ataacgattc cagaggaaag ctccagtaca agagaggaaa ctcccaggaa
    13921 acaaatatca gcggcgcgtt ttaatgacag ccgtattttt gtaatatgaa accggttgtt
    13981 tttctttata aaatggacag acatgatgag catactgatc acaggagcag ttgcagtcgc
    14041 agtggcggct cctgccattt ccatgccaag cggatagata aaaatatagt ccagtacaat
    14101 gttggcaaga cttccgataa gcattcccgc catagaaagt ctgggagctc cgtcgtttct
    14161 cacaaaacaa agaagaagat tgtttccgag aaagagcggg gagaagagaa gcagtatgcg
    14221 gatgtagtcg gaggcgtaac cgatcgtgtc gtgatcggcg ccgagtatgg cggaaatctc
    14281 ttctgaacaa aatgctcccg caaaggagaa gaaaagtgcg cagagagcgg ccaaaagcag
    14341 agcatgtgta aaagcagtgc ggtgtgtatc gctgtccggg cgtgtcgatg aaagcgagta
    14401 gcgggcggct ccgcccatac cgatcatcag accgatcccg ttcataaggt tgtatgcagg
    14461 gagcgtcaga ttgagcgccg cgagggcgtc tgcgccgatt ccccttgcaa tgaaaaaaac
    14521 gtcggccaga atatagcagg aaaatccgat catgccgagg acgtttgatg atacatattt
    14581 aaaaaaagta tggaagatcg attgttcgtt ttgtcttgca gcgttcataa aagttccttc
    14641 cgtaaaaaag gcatctgacg atgcattttc tctgaaaata tttcaagaaa gagtgcgaag
    14701 ccaaatgcgt tgaaatgtaa gctttctatc aaaagtctat tttgtatggt cttattgttt
    14761 gcgacgctat cgtaccatag aacaaaggga aaatcaaatc ttttttaatt ccccgatcag
    14821 gtgtatgata taatagatcg gcgcaaacgg aaatagcgcc ggaaaatgag caaaacggaa
    14881 gcagatgcga aagaaacaga tgcgatgaaa gcaggcgcga aagaaacaga cagaagaatg
    14941 acggaaaggg gtttataata tgaataagaa ggaaatatta gagataagaa agcagtttac
    15001 tccggcaaat tgtgcgatta cacgtatatg cgggtgttat gtagatcatg agaaagaaaa
    15061 gaagatggaa tcaaaagaag cttttttgtc attgccggaa gaagaggcgt ttaaatattt
    15121 tgacattttt aaaaagacgc tttccggtac ggtcgggaaa aatatattga atatggaatt
    15181 tccgatcgat gcggagatgc ccgggggaac gcaggagttt cttttgaagc ttcgcagcag
    15241 caagcttcag gatgatatgc ttttggaaga gttttatgat aaagtcatcg aggcatacga
    15301 ctgtgccgag aattattaca ttattttgat ccatgcgatg tatgatgttc cgggaaaatc
    15361 ttccgacggg atcgaaatgt tcgacgcgtc tgacgaagtg tatgaatatt tgcttatgag
    15421 tctctgcccg gtgtctttgt cgaaagcagg attgagttat aatgcggaaa gcaactgcat
    15481 tcaggatcgg ataagagact ggatcgtaga tatgcccgat aaaggatttt tgttccctgc
    15541 ctttaatgac cgaagcacgg atttacatag tatgctatat tatacgaaga aatcagaaga
    15601 tttacagccc ggaatgatcg atcagctttt cggaacgaag atgccgatgt ctgccgatac
    15661 gcagaaagaa acgtttaaaa tgttgatcga agacacgctt ggtgaggacg gagattatga
    15721 gaccgtcaga aatattcatg aaacgctgaa tcagttgata gaagaacata aggaagaacc
    15781 ggaaccgctg gcgcttgatc tgacagatat gaagaaagtg tttgagcaaa gcggtgtaga
    15841 ggcggaaaag atggaaagtt tcgaccgcaa tttcacggaa aatgcaggag aaaaaacatc
    15901 gcttttagca tctaatattg cagagacgag aaagtttcag attgaaactc cggacatcgt
    15961 tattaaggta aatccggaaa gagcggatct cgttgagacg aggatcattg acggacgccg
    16021 ctgtcttgtg ataccggtgg acgatcatat agaagtaaac ggaatcaatg tgcagacgat
    16081 caaaatgaaa gaacgggaag aaaatcagga gacatataat taacctacta aataaaatta
    16141 gtcaaaaagt atgaaaaaaa tgtgaagtca acatgtatat gttgactttt ttgtgttata
    16201 ttactaatat attatttagt tatctaacta ataaataaaa agtaagaggg aggcataaca
    16261 tgtttcaatg tgatataaac gatgctccgg tgatcgggat attgggaatt gtgtcgcacc
    16321 gggcgaaagt tgcggcaaaa gatatgtaca gtgtatttga tctaaacaga agtcaggcaa
    16381 gtattttact tacgcttcat cactgtgagt ctatgtcgca gaaggatctg gcaaagcagt
    16441 tgaatattac cgctccgtcg attacatcat cgatccgtaa aatggaacag tttggatata
    16501 ttgcaagaca gacagatcct gcggatcaga gagttatgcg gttggcgctt acagagaaag
    16561 gacgttcgtg cattcaatct ataaaagacg tgacggataa aatggaggag atcctgctta
    16621 aaggaatgag cgtagaagaa aaaatattgt ttcgcaggct tttagttcat gtaaacaata
    16681 atattgatca atatgaaagg aaagaaaaga tatgaaaaac ttatttaagt atgcgtccga
    16741 gcactggaaa gcgcttcttg cgatcgtggc cattttgatc gtgcaggcgt attgtgatct
    16801 gtctttgcct gcatatactt cggacatcgt caatgtggga atccaacaag gcggagttga
    16861 agatcatata ccggatgcga tttccgcgga agatatggag acacttttgc tttttacttc
    16921 tgaaaaagac ggaaaaactg ttttgtcggc atatgaaaag gatgacaaaa catatgaaga
    16981 acaggcttat gtcttaaaag atactgtaaa agaagatacg gataggacgg aaaaattaag
    17041 cggtattctg gcagcgccta tgatgatggc ggcaggattt gaatcaggaa gcgatatgac
    17101 cgcagatatc gaagaacagt tgaaagcaca gcttcctccg gaaatgatat cggaagatat
    17161 gacggttttg gatattttga aaatgatgcc gcaggagcag aaacaggcat ttgtatcgga
    17221 gatagaaaaa aagacggaag aacttcctga tacgatcaca gagcaggctg ccgtaaatta
    17281 tgtaaaagaa gcttatgcag atctcggtat cgatatggat gaattgcagt ttcgctatct
    17341 gttttcaaca ggagcaaaaa tgatcggtct tgcatttctc ggaatggtgg caagcgttct
    17401 tgtcggattt cttgcatccc gcgtcggagc ggcggcagga cgcgatctaa gaggaagagt
    17461 gtttaagaaa gtcgtaggat attcaagcaa tgagttcgat catttttcca cggcgtcttt
    17521 gatcacgaga agtacaaacg atatccaaca agtacagttt attatcgtga tgctgcttag
    17581 aattgtactt tatgcgccga ttcttgcgat cggaggcatt gtgcaggtat ttcagacaaa
    17641 tgtttcaatg tcctggatca tcggtctggc agttgttttg atcgctttag tcgttttggt
    17701 tttgtttgcg gttgcaatgc cgaaatttaa gagcctgcag aaattagttg ataaagtgaa
    17761 ccttgttatg agagaaatat tgaccggact tcctgtgatc agggcgttta gtacagagaa
    17821 gcatgaggaa aagcggtttg acaaagcaaa tatggatctg atgaaaacaa atctgttcgt
    17881 aaatcgcgcg atgacgttta tgatgccgat catgatgctt attatgaacg ggatctcggt
    17941 tttgatcatg tggtccggtg caaaaggaat caacgacgga cagatgcagg tcggagatat
    18001 gatggcgttt atccagtata cgatgcagat tattatggga ttccttatga tatgcatgtt
    18061 gtcggttatg cttccaagag cggctgttgc ggcagatcgt gtggatgagg ttctgtccag
    18121 caggacggtg atccatgatc cgaaaacacc gaaaaaattt gaagaaaaac aaaaaggtgt
    18181 gctcacattc gaccatgttt ctttcaaata tccgggtgcg gatgaaaatg ttcttgaaga
    18241 tattacattt acggcaaaac cgggagaaac gacagcgatt atcggaagta ccggaagcgg
    18301 aaaatcaacg cttgtcaatc tgatcccccg tttttatgat gtgacggacg gaagtatccg
    18361 tttggatgga acagatattc gtgaagtgac acagcatgat ttgagagata aacttgggta
    18421 tgttcctcag aaaggactgt tgttctcagg tgatatcgca tcgaatatta tgttcgggaa
    18481 tccggaaggc ggcgggcagg agatgaaaga agctgcgcag atagcgcagg caacagagtt
    18541 tatcgaagca aagccgaaca aatatgaaag tcctatttcg cagggcggat cgaatgtgtc
    18601 cggaggccag aaacagagac tttcaatcgc aagggcgatc gcaaaacgac cggaagtgtt
    18661 tatttttgac gacagttttt cggcgcttga cttcaagaca gacgttgctc tacggaaagc
    18721 tttgaaaaag cggacgaaag aaagtacggt gctgatcgtg gcacagcgaa tcagtacgat
    18781 tttaaatgca gaacagatca ttgtacttga tgatggaaag attgcaggaa tcggtacaca
    18841 taaagagctt cttagaaact gtgaagttta caaacagatt gcggcatccc agttgtctga
    18901 aaaagaactt caagatggaa tgcaaagtga agacagaaaa acggaagata taaaaagtga
    18961 aacgataaaa acagaagaaa gaaaagaagc aatcagtgca aaaacagcgg aacaggaggt
    19021 gagaagcgat gtctaggcac ggaatgaaag gtcctcatgg aggaatgcga ggaggagcaa
    19081 aagcaaagga ttttaaaggc tcgcttaaaa aacttgtaaa atatatgagc gtatataaag
    19141 tgcagatgct ttttgtcgct gttttcgcag tatgcggaac ggtatttaac attgtcggac
    19201 cgaaaatatt aggtaaggct acaacagaga tttttaacgg gcttgtcagt aaagtatcgg
    19261 gcggatcggg aatggatttc ggaaaaatcg gacagatcct tcttattact ctcggtctgt
    19321 atgtagtcag cgcgctttgt tcctttattc agggaatgat tatgaccgga atctcacaga
    19381 aaacgacgta ccgattgaga aaagatatta cggaaaaggt caatcggatg ccgatggatt
    19441 attttgatac gaagcctgtc ggagaggtgc tctcccgtgt gacaaatgat gtagatactc
    19501 tcggacagag tttgaaccaa agcgcgacgc agcttattac ttctgtgacg actctgatag
    19561 gagttctcgt tatgatgctt tcgatcagtc cgcttatgac ggttgtggcg ctgttgatcc
    19621 tgccgatttc cgttggcctg atctcattcg ttatgaaaca ttcgcagaaa tatttcagcg
    19681 gacagcagga atatctcgga aatgtaaacg gtcaggtcga ggaagtgtac agcggacaca
    19741 acgtgatcaa ggcatttaac aaagaagacg atgtgatccg tgaatttgac cggacaaatg
    19801 ataaattgta tgaatctgca tggaaatccc agtttttctc tggaatgatg atgccggtca
    19861 tgcagtttgt agggaactta ggttatgtag gagtagcgat actcggaggt tttctggcga
    19921 ttaaaaagac aatagaagtc ggagatatcc agtcatttat tcagtatgtg agaaacttta
    19981 cacagccgat ccaacaagtt gctcaggtga caaacatgct tcagcttgcg gcggcatcat
    20041 cggagcgggt gtttgaattc ctcgaagaaa aggaagaaga tcagacggtt gaacaccctg
    20101 tttcggtaga aggacttcac ggaaatgtac agtttgaaaa tgttcatttc ggatacaatc
    20161 cggaaaagat catcattaac gatttctctg caaatgtaaa agaaggtcag aaaatcgcaa
    20221 tcgtcggtcc tacaggagcc ggaaaaacaa cgatgatcaa actgctcatg cgcttttatg
    20281 atgtaaacag cggttcgatc aagatcgacg gccatgacgt aagagacttc aacagaagcg
    20341 aactaagaga aatgttcgga atggtacttc aagatacatg gctcttccac ggaacgatca
    20401 tggataacat ccgttacgga aaactcgacg caacagagga agaagttata caggcagcaa
    20461 aagcagcaca tgttcaccgt ttcgtccaga cacttccggg aggctatcag atggaaatca
    20521 atgaagaagc aacaaacatc tcacaaggac aaaaacagct tcttacgatc gcaagagcaa
    20581 tacttgcaga tccgaagatc ctcattcttg acgaagcgac aagttccgtc gatacaagaa
    20641 cagaagtaag aatccaaaaa gcaatggata atttgatgaa aggcagaaca agtttcgtta
    20701 tcgcccatag attatcgaca atccgagacg cagatctcat tctcgttatg aaagacggcg
    20761 atatcatcga acaaggaaca cacacacaac tcctcgccca aaacggcttc tacgccgaac
    20821 tatacaattc acagtttgaa tcaacagatc agacctgcgc ataaaaaaga ggactccgca
    20881 gcgtaagctt gcttacaagg tgcggagtcc tcttttttaa gcatagggcg gacgcccgtc
    20941 agtgagatga agagcgaagc gatgaaatcg aactggggtc tgatcggacg gagagaaaac
    21001 ataacctgcg cataaaaaag aagttctctg ctgagcaagc ttgcttgcaa aaggcagaga
    21061 cttctttttt aagcataggg cggacgcccg tcagtgagat gaagagtgaa gcgatgaaat
    21121 cgaactgggg tctgatcgga cggagagaaa acataacctg cgcataaaaa agaagttctc
    21181 tgctgagcaa gcttgcttgc ttacaaggtg cggagtcctc ttttttaagc atagggcgga
    21241 cgcccatcag tgagatgaag agtgaagcga tgaaatcgaa ctggggtctg atcggacggt
    21301 ggagttgagt tctgatcgga tgcaaatgat ttttgtatgt ggtatgatgg gagttgaact
    21361 gcactgagtt tttacaaccg aagcttgagt gcaagatctt tcgcacatat aacacgaaag
    21421 aatactaaaa aggaaagcag tttaaagaac gagtattctc aggaacaggt gaggtggcaa
    21481 catgttaaaa aagagttttt atttttttat gtcagttgta gaaacaggaa gcttttcgca
    21541 ggcggcgaaa aagcactatt tgtcgcaggc tgccattagc cagcagattt ctaaactgga
    21601 agaagaagtc ggagttcgtt tatttgacag gagtaaatac cgccctgaat tgacggaagc
    21661 cggtaaatat tattatcaga agatcaaaca gttatctgag gaatatgaga aaatcgagaa
    21721 acagacgcgt tatattcaaa aaaagaattc gcagaaaata gtagtgggga ttacaggtcc
    21781 gtttgaaaat aaatatcttc cccgtattat caatgaatat aaagaagggc atgaaacgca
    21841 ttttgatgtt cgtgtttata catttgaaga ggggaaaaag ctgttggagg caggagatat
    21901 tgatattgct tttggtctgt catcagagtt ttctgtaaac ccggatattt cttatgaaac
    21961 gattcatcag tcggaaacgt gtattgtatg cagcagaaaa aacagattaa gtcagtataa
    22021 aagcatcaac cccattttag taaaagacga gccgatgatc acgttatctt cgcagatggg
    22081 cagaaagttt tatgatgatt ttatgaaggc gtttatattg gatgggtttg aaccgaatat
    22141 tgtaaaagaa gtgaattctc tttcggagta ttttatatct ataaaactgg atgaaggaat
    22201 aggatataca ggcagagagg ttgtgccgga agaggaagat ctgtgcactg taaaaatagt
    22261 aggaagtcat catcatgcag attttgcggt ggcttattta aaagaaaata aaaaacaaag
    22321 tgttgttcag ttttatgaat atattgtagc atattttaaa gattataaga aaaacttata
    22381 gtctttatag aaaagcaggt agtttctttt tgcttgttaa aatattatca ttacagtatg
    22441 aaaagcaaag gagaaatgaa acgatgggta aattattatt gacaggtgtt gacggaaatt
    22501 taggtgaaac tgccgctgaa attttgctta ctttagaacc gaaagagaat ctgatctttt
    22561 gtggttatag tgaagaggcg ctcaaaaaat atgcagatat gggagtcgag actcgtcaga
    22621 caaactttaa caacgcagat ggattgtcgg aggcattcaa aggagcagat gcgctggctc
    22681 ttatttcgat gccgtttgta ggagcgaaaa ggcagaaagc tcataaaaat gcgatagatg
    22741 cggcaaaagc ggcaggagta aaacagatta tttatacttc gttagtgaat gcagacgatg
    22801 agacaaatcc tagtgttgaa aagaaagacc acatttatac agaaaattat ataaaagagg
    22861 tcggcttaga ttatcagttt atgagaaatt cacagtatgc agaggcgatg gtcacaaatt
    22921 actttactta tgtaaaaatg ggaactccgc tcacaaattc acagggcgac ggattgatgg
    22981 cttatatctc cagaaaagac tgtgcgaagg ctgtggcata cgcgctccac agatcgggcg
    23041 agtttacacg gaaagtttgg gacattaacg gaccggagct gatgacgatt actcagttta
    23101 tcgagatcgg aaatgaatct acaggaaata atctgacgtt tcagaatgta acggatgaag
    23161 aaaactatca aatatgggat gctatgggag tgccgagaac gacggacggc gt
//
