LOCUS       c00039_NZ_JRMW..       16507 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JRMW01000040.1 Anaerococcus lactolyticus S7-1-13 contig40, whole
            genome shotgun sequence.
ACCESSION   NZ_JRMW01000040
VERSION     NZ_JRMW01000040
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:30:07
            Original ID  :: NZ_JRMW01000040.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16507
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16507
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3517:6507]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3518..6507
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16507
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16507
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(333..974)
                     /locus_tag="ctg39_1"
                     /transl_table=11
                     /translation="MDLREIKIFKNLIDQDLDLIRSKTEFIEKTYGKSEYIFMAGDKSG
                     DLFYLMEGVLNVYQIDSNGKRFIFQNFTKPTLFGEVYSYLGEPFEFDCECASSCKILII
                     KDFRKIFEPPCPESFLRSYINFLSHKCLALSKKNQITSQASLRQKICKYLLETENQGKV
                     KLSMKREDLADYLSTTRPSLSRELSKMADEGIIKVGGDFIEILNREGIEF"
     CDS             complement(1220..2836)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Prismane"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_2"
                     /sec_met_domain="Prismane (E-value: 1.2e-176, bitscore:
                     580.3, seeds: 159, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFCYQCQETAGNKGCSKVGVCGKNESVANLQDLLIYTTKGLAGLV
                     VKKGKACAKVYDRISNNLFITITNANFDESAILDAIKKTMAFKEKIMGKIGTEGLTDIE
                     KYISYDDEELIRKAVEVGVLNIINEDERSLVELITYGLKGMAAYNHHANVLGYRDEEVD
                     FFIASALAKTTHNDKEITDLIDLVMETGSHGVKAMALLDKANTETYGNPEITEVDFSAG
                     KNPGILISGHDLHDMKMLLEQTQGTGVDVYTHSEMLPANYYPAFKKYDNFHGNYGNAWW
                     KQNEEFEKFNGPILMTTNCIVPPKKDNTYLDRMFTTSNAGYPGAFHIEADENGFKDFSQ
                     IIEMAKKCQAPENLEDITVVGGFAHNQVLALADKVVEEVKAGNIRKFVVMAGCDGRNPK
                     RSYYTDFAKSLPEDTVILTAGCAKYRYNKLGLGDINGIPRVLDAGQCNDSYSLVQIALA
                     LKDVFGLDDVNDLPIAYNIAWYEQKAVIVLLALLSLGVKNIHLGPTLPAFLSPTVIDFL
                     VENFNIAPNSTVEEDLEKMIG"
     CDS             3086..3283
                     /locus_tag="ctg39_3"
                     /transl_table=11
                     /translation="MRISIKRAIGLNIVVIFILAITFFEDLQMNSPHQKEALLIIFLGE
                     FAYWLTIIIGLYVIKRKNNL"
     CDS             3518..5773
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_4"
                     /sec_met_domain="Gly_radical (E-value: 8.6e-43, bitscore:
                     137.4, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 7.2e-304, bitscore:
                     1000.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVKAYDGFKGELWKDEINVRNFIQENYTPYEGGDDFLAGKSEKT
                     TKLFAVVEDLINKEIRESYRNADTSRFSSIDGFDAGYIDKENEVIVGLQTDEVLKRIVN
                     PYGGYRMVEQSLEAYGQEMDPVQAKYFKEFRKTHNEGVFDAYTKDMRTARHVGLLTGLP
                     DAYGRGRIIGDYRRVALYGIDRLVEEKKKDLDKIEIDENNLEATIRLREEVSEQIRALG
                     KIKNMAAKYGIDISKPATNAREAAQFLYLGYLAAVKENNGAAMSIGRNAGFLDIYIKRD
                     MDRGILDEVGAQEIIDQLVIKLRLVRHLRTPDYDEVFGGDPTWVTESIGGMGLDGRTLV
                     TKTAFRYLNTLINLGSAPEPNMTILWAEKLPEGWKKFCSKVSIMTDSIQYENDDLMRNM
                     YGDDYAIACCVSAMEVGKEMQFFGARANLAKSLLYAINGGVDEKKKNKDGSIIRLFNDV
                     EPITTEYLDYDKVLANYKKVLSELAGLYVKTLDVIHFMHDKYAYEAGQMALHDTYVKRN
                     LATGVAGLSIAADSLSAIKYAKVKPVRDENGIAIDFETEGDFPKYGNDDDRVDQIAVDI
                     LTYFSNELKKHATYKNAKLTLSALTITSNVMYGKKTGTTPDGRKAGEPFAPGANPMHGR
                     DESGALASLNSVAKLPYECVCEDGISNTFSIVPDALGKEDEVRIDNLVNIMDGYFGQDA
                     FHLNVNVLQREKLLDAYHNPDKYPNLTIRVSGYAVHFNRLTDEQKREVLERTFHNHQ"
     CDS             5788..6507
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 59.8;
                     E-value: 1.2e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_5"
                     /sec_met_domain="Radical_SAM (E-value: 5.6e-30, bitscore:
                     97.0, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKLHSIETMGLVDGPGIRTVFFLSGCPLRCVFCHNPDTQSLDYG
                     RDVTVDEIVKRALRMKPYFKNGGGVTLSGGEPLASGAFVLETIRALHKEAIHVAVDTSG
                     VGDEKYYDDIAREADLILLDIKHYDPYFFYEITKNYQDKLIKFMESIKKTDTRVWIRHV
                     MMPFVTDTKEDMDGLVDFIRPIKANIDKIEILPYHKLGVCKYADLGKPYRIKNMEAMDK
                     DKAKNFEIYANNMLKSL"
     CDS             6517..7197
                     /locus_tag="ctg39_6"
                     /transl_table=11
                     /translation="MNDYKKDEKSFLAFLSDQELQRFKYRPQVLAYRRGDMIFSFGDSA
                     DFMYIILEGFIKISTYLSDGREQILYIYGEGDFVGAHNLLTEEEYIYEARALTKAKLLI
                     ISRIDFNSILKKNNKVLIKILDQSFRRIRRSEELIDRLSTINADMKVAKLLLDLADDVG
                     IVKKDGVLITSHLSREELGSYSGVVRETLSRKLSNFEKMGLIKIIGRNEILITNIRALE
                     KMTS"
     CDS             7370..8635
                     /locus_tag="ctg39_7"
                     /transl_table=11
                     /translation="MNKQTFKIMLAYVGVLTGAGLASGQELLQYFVSLGINGLVGISLV
                     GILHMVIGGILLILGSHYLATDHSDVFDEITNKFISKFMDISLIFTCFVVGFVMLAGAG
                     SNLNQAFGLNVNVGRVLCALLIIVVGMMDFSKVSKIIGSFTPFIVGFVLIGSVYTFIKF
                     KPDWQALNAFAVKLPSNFDNVGFAVLNYFGMCLMTAVSMGLVLGGDELSTENAGKGGLM
                     GGAIVGIMGVLITLTLLIRVEEVYNLDIPMLYIIEDISPILGFVMALVVFGMIFNTGIS
                     LFYALARRFSNGEERRFKIMLVTITGVGFILSFLGFKKLVSIFYPIIGYIGIFMMALLV
                     FAYFKERSAIRRESMKRLGIRHYMRKKLDDDLDFTKQDEERLNKLIDRSHIDNDQIEEK
                     TEETVQEAIDNDEEPLTDHGEN"
     CDS             8771..9502
                     /locus_tag="ctg39_8"
                     /transl_table=11
                     /translation="MEVSYQAIKTGRFINRGFLNGPLCPIYGFGALGVIYFLTDIAKTN
                     KLYLFFGSIFIATSLELVGGFLLEKIFHKKWWDYSDMRFNLGGYICLEFSILWGLACFV
                     LYEAIHPLIVRFFAFLNPKFIFYANIILLAIFAVDMAQTILTLVGLNKKFKKLQAASED
                     IREVSDDIGKRVYDRTMSIKEKREEIKPRVKELEAKRNKIRMDIANKFDKMSEKRLIKA
                     FPNLIEDLVEKIDKDIENIEK"
     CDS             9593..10210
                     /locus_tag="ctg39_9"
                     /transl_table=11
                     /translation="MLDNKGFDLWADGYDESVGLCDEENTYPFAAYKDILNAIYKDVLG
                     AEAKNVLDIGFGTATLASRLYDKGLTIYGQDFSEEMMKIAKEKMPNANLYVGDFGRGLV
                     SSLLNHKYDAIVATYSLHHLSDEDKVSFIKTLLSLLNVGGKIYIGDVAFKTRRDLEATR
                     EKFKNEWDEDEFYFVYDELKNHFSNLDFITYSYCSGILTITN"
     CDS             10354..11514
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_10"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 6.5e-32,
                     bitscore: 102.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 4.5e-28, bitscore:
                     89.5, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIIVMGMGYVGLSNAVLLAQTNEVIGLEIDQKKVDLINNKKSPL
                     KDDYLIDYLANKKLNLIAKTSGEEDFKDCDLAILALPTNYDEVEKFFDTSFLDDAIKMI
                     KSIRKDLPILIKSTIPIGYTEGKNKEFNCENIIFSPEFLREGRALYDSLHPSRIIVSDK
                     TEIGKKIADLYKSEALNNPDVILMGRSEAEAVKLFANTYLAMRVSFFNELDNYAIAKGL
                     DSKSIIEGVSADPRIGDHYNNPSFGYGGYCLPKDSKQLYANYENIPSALFKSIIDSNEV
                     RKDFVSEDILAKNPQTIGVYRLVMKKGSDNFRKSAIFDVINNLKSKGANLVIYEPNLDG
                     DDFEGMKLIRNLEDFKKVDLIIANRVEDDLKDVKNKLYTRDLFERD"
     CDS             11515..12192
                     /locus_tag="ctg39_11"
                     /transl_table=11
                     /translation="MTEKKNVPQVHSKLRKSFISVPEEIYKASGIKIFDKRIKSLLFTT
                     DLAIIRNSNADSIMAVYPYTPLNSITEAIISIASVPCFIGVGGGTTQGPRSRFVAYYAE
                     LAGAYGVVVNGPIPHEDIREISKFVDIPVIATVSSLKDDYKAKIEAGAEILNVSGGKYT
                     ADLVRHIRADIGDDFPIIATGGKDGESILETIKAGANAISYTPPSSSDVFGSMMDTYRN
                     EDI"
     CDS             12192..13124
                     /locus_tag="ctg39_12"
                     /transl_table=11
                     /translation="MYSGYFTDVGNIKVGHAQDLEGGTGLTIIIPDSGNTAGVDVRGGA
                     PGTRETDLLNPINQVSEVSSIILSGGSAYGLEAASHLMKILEKEGRGFNVGVGVVPIIS
                     QAVLFDLSYKDSKARPDAKMTEKAYNNARYEDKSQGIVGAGTGATVAKALGPDHLVKSG
                     LGQASIKKGDLVVSAIVAVNAFGDIFDYHKALQLAGPIVDGKMLRTVDMIDKILGSFAD
                     IKPANTTIGAVATNATFTKTELTKIAGMAHDGYARSINPVHTLFDGDTIFSLATNKVQA
                     NINLVGTLAAEAMSMAIANAIYSSREKNN"
     CDS             13710..14057
                     /locus_tag="ctg39_13"
                     /transl_table=11
                     /translation="MKYLKEFCYILFFLLLGFIAKKLTGLPIPEPVFGMIFLFIALCSK
                     FLKVDDIGETSDFLTSILAFTFTPLGVALMVQFDVIKDNAVKILIVMTVSCLITMAVTA
                     KVVELVQKVRK"
     CDS             14059..14799
                     /locus_tag="ctg39_14"
                     /transl_table=11
                     /translation="MSEFLNTYVADNDFFGIILSIVMFRIGMVINKKTKIAVLNPLLLA
                     IVFCIIFLKLTGISYENFNKGGKYISFMIAPITVALVVSLYRNIEKLKANLIPILIGVI
                     VGSFVAILSAYLLSKLFGFDRDLTLSMMPQSVTTPIAKSLTEEYVAKFGADEVTIKTFA
                     AITAITVILRGTVGAIAAPTVMKVMRVKDPVAQGIGIGTSSHAMGTSKAIEMGEVEGAM
                     SGLSIAVAGICTVVLMPLFIILLF"
     CDS             14823..16007
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_15"
                     /sec_met_domain="CbiA (E-value: 2.8e-08, bitscore: 26.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKKIFMYTGKGGVGKSTLASSTALISAKKNIETILISIDSAHSL
                     SDIFSIKIGNTLTKVRDGLTAIEFDSSKILEEEFPSIKASLANEFRKVDFSKISYNSSF
                     DMPFVVNILSLLKILDIYENYDFENIVVDCPASASTFAYLKIPEMLSWYLEKFFGVGKG
                     IIRTLRPISKYKYQIDLPDKEALDKLEVTYQRLKKLEDILKNKTISTIRLVGLAEKMVI
                     EESKRDFAYLSLFDYNVDGFFANRLLADEDIDFIKKRIQIQNKRLEEIKVCFYNLPIYK
                     IGLMNKDLNSLVDLEDFADSLDFKDNLLDIRPFKEGHYFEKIPYGYILKINIPAVEDVE
                     VYKKGSDINIKLKDIKRIISLPNVCINSEIGKYYCQGDELFIYLESKDQEELSV"
ORIGIN
        1 aaatctcgta gaactgagac aatcaataga tagtccagca aatgcctaga aggagcaaag
       61 cttcttcgaa aggatatgga ttatttacaa taataattga tatttaaaaa gacaagtcaa
      121 ttaaggcttg tctttttttg tggtaaatat ttttgaaaaa tattctataa atctatttat
      181 tattatattt tatctttatc ttttattaaa tttttctatt tacggttgaa tctttataaa
      241 aaggggaggc ccaagggaac tcttacgtag gctcaaaagc aaaatatagt catgcattca
      301 gcataatttc aaattaaaat caccacaaaa aactaaaact caattccttc tctatttaaa
      361 atctcaataa aatctccacc gacttttata atcccttcgt ctgccatttt tgatagctcc
      421 cttgataggc taggtctggt ggtggagagg tagtctgcta gatcttccct tttcattgaa
      481 agttttacct tgccttgatt ttcagtttct aggagatatt tacagatttt ttgacggaga
      541 cttgcttggg aggtgatttg gtttttcttt gatagggcca ggcacttgtg ggataggaag
      601 tttatatagg atcttaaaaa actttccggg catgggggct cgaagatttt cctgaaatct
      661 tttatgatta aaattttgca agagctggcg cattcgcagt caaattcaaa gggctctccc
      721 agataggaat aaacttcgcc aaaaagtgtg ggttttgtaa agttttggaa gataaacctc
      781 ttgccatttg aatctatctg gtagacattt aggacgcctt ccattaggta aaataagtca
      841 ccactcttat caccggccat aaaaatatac tcgctcttac cataagtttt ttctataaat
      901 tctgtctttg accttatgag gtcaaggtct tggtctatta aatttttaaa aatttttatt
      961 tctcgtaaat ccattaatat gtcctttcta agtcctatta tactttattt ctaaagttaa
     1021 aagtcggcac gcttgtgccg acaattataa atattacata gtaaatccta agttcatgag
     1081 attcttcctc gccttgctcg tctgcctctg cacgctctat gccgctaggg caattttcct
     1141 accatacatt tgtctcctcg agccgacggg cttgccttaa atgtggttag ggcttcaaga
     1201 atgacaggtg agaagtaatt tagccaatca ttttttctaa gtcttcttct actgttgaat
     1261 ttggagcgat gttgaagttt tctaccaaaa agtcaataac tgttggactt aaaaaggcag
     1321 gaagagttgg tcctaggtgg atgtttttaa ctcctagtga aagtagggca agtaagacta
     1381 tgactgcctt ttgctcatac caagcgatgt tgtaggcgat tggtaaatca tttacatcat
     1441 caagtccaaa gacgtctttg agggcaaggg caatttgaac cagtgagtaa gaatcgttac
     1501 attgacctgc atctaagact cttggaatcc cgttgatatc cccaagacct agcttgttgt
     1561 aacggtattt tgcacaacct gctgttagaa taacagtatc ttctggcaaa gatttggcaa
     1621 aatctgtgta ataagatctc ttaggatttc ttccgtcaca gcccgccatt acaacaaatt
     1681 tcctaatatt gccagccttt acttcttcca caaccttatc ggcaagggca agaacttggt
     1741 tgtgggcaaa accacctaca accgttatat cttcaagatt ttctggagcc tgacatttct
     1801 ttgccatttc aattatttgt gaaaaatctt taaaaccatt ttcgtcagct tctatgtgga
     1861 aagctcctgg gtaacctgcg ttagatgttg taaacatcct atctaggtaa gtattatctt
     1921 tttttggtgg tacaatacaa tttgttgtca taaggattgg gccgttaaat ttctcgaatt
     1981 cttcgttttg cttccaccaa gcattgccgt aattaccatg gaagttgtcg tattttttga
     2041 aggctgggta ataatttgca ggaagcattt ctgagtgggt gtaaacgtca actccagttc
     2101 cttgggtttg ttcaaggagc attttcatat cgtgaaggtc gtggcctgaa attaaaattc
     2161 caggattttt tcctgcagaa aaatctactt cggtaatttc tggattgccg taagtttcgg
     2221 tgttggcctt atctagtagg gccatagctt tcacaccatg agatcctgtt tccattacaa
     2281 ggtcgattaa atctgtaatt tccttgtcat tgtgagttgt ttttgcaagg gcagatgcta
     2341 tgaagaagtc gacttcttcg tccctatagc caagcacgtt tgcgtggtgg ttgtaggctg
     2401 ccatgccctt tagaccgtag gtaattagct caacaaggct tctttcatcc tcattaataa
     2461 tatttaaaac cccgacttca actgcctttc ttattaattc ctcatcgtcg tatgatatgt
     2521 atttttcaat atcagttaga ccttctgtgc caattttacc catgattttt tccttaaagg
     2581 ccatggtttt cttaattgca tctaaaatcg cactttcatc gaaatttgca ttggtaatgg
     2641 taatgaaaag attgtttgaa atcctatcgt agaccttggc acaagccttg ccttttttta
     2701 ccacaagtcc tgctagaccc ttggttgtat aaattaaaag gtcttggagg ttggctacag
     2761 attcattttt accacaaacc ccaaccttac tgcatccttt atttccagct gtttcttgac
     2821 attgataaca aaacatatat ttttcctcat ttcttttttt ctcaaacttt tatcttataa
     2881 tcctattata aaaaaattta ggaaagatat ccgtaactaa tgttacaagg atagcttttt
     2941 aattttgaaa ataatataaa aattgtttta atattatctt tcataagaaa agaatcttgt
     3001 ggttcaaaaa ctaatcaagt attataatac caaaataaat aggaagactt tggcaaagga
     3061 atcatcaatt agtaggagtt agaaaatgag aattagtata aagagagcta ttggacttaa
     3121 tatagtggta atttttattc tagctataac tttttttgaa gatttacaaa tgaatagtcc
     3181 ccaccagaaa gaagccttat taattatttt cttaggagag tttgcttatt ggctaactat
     3241 tataatcgga ttatatgtga ttaaaagaaa aaataattta taagatgttg ttcttacaaa
     3301 tgtagttaag cttaaaatta caaaaacaat agaacttggt ggatataact attatttagt
     3361 ataaaattta tatttattta ctataggcga gcaattgtgc ttgtcttttt ttatgttgaa
     3421 gtgattcaaa tcacatacaa gaaagctttt tccagataga ataggggcag atagtcaaaa
     3481 aaacttcggt ttttaaaata tatattagga ggaaaaaatg gaagtaaaag catatgatgg
     3541 atttaagggc gaactttgga aagatgaaat caatgttcgt aactttatcc aagaaaacta
     3601 caccccatat gaaggtggag atgatttttt agctggtaag agcgaaaaga ctacaaaatt
     3661 atttgctgtt gtagaggatt tgattaataa agaaatcaga gaatcttaca gaaatgcaga
     3721 tacaagcagg ttttcttcta tagacggttt tgatgctggc tatattgaca aggaaaacga
     3781 ggtcatagtt ggtcttcaaa ctgatgaagt tctaaaaaga atagttaacc cttacggtgg
     3841 ttacaggatg gttgagcaat cccttgaggc ttatggccaa gagatggatc ctgttcaagc
     3901 aaaatatttc aaagaattta gaaagactca caatgagggt gtttttgatg cctataccaa
     3961 ggatatgaga acagctagac acgttggtct tttaacaggt ttgccagatg cctatggtcg
     4021 tggtaggatt atcggcgatt atagaagagt tgccctttat ggtattgata ggctagttga
     4081 agaaaagaaa aaagacctag ataagattga aattgatgaa aataacctag aagcaactat
     4141 cagactaagg gaagaagtta gcgagcaaat cagagccctt ggcaagatta aaaatatggc
     4201 agctaagtat ggtatagata tttctaaacc tgctacaaat gcgagagaag cagcccaatt
     4261 cttatacctt ggctaccttg cagctgttaa ggaaaacaat ggtgcagcta tgtcaattgg
     4321 tagaaatgca ggcttcctag atatttatat caagagagat atggataggg gcatccttga
     4381 tgaagttgga gctcaagaaa taattgacca acttgttatc aaattaagac ttgttcgcca
     4441 cctaagaact ccagactatg atgaagtttt cggtggagat ccaacttggg ttacagaatc
     4501 aatcggtggt atgggtctag atggtaggac tcttgtaaca aagacagcct tcagatacct
     4561 aaataccctt ataaacctag gatcagctcc agaaccaaac atgacaatcc tttgggctga
     4621 aaaacttcct gaaggttgga agaagttctg ctctaaggtt tctatcatga cagattctat
     4681 tcaatatgaa aatgatgacc taatgagaaa tatgtacggc gatgactatg ctatagcttg
     4741 ttgtgtatct gctatggaag ttggcaagga aatgcaattc tttggcgctc gtgccaacct
     4801 tgcaaaatca ctcctttatg caataaatgg tggagttgac gaaaagaaga aaaacaagga
     4861 tggtagcata attaggttat ttaatgatgt tgagccaatt acaacagaat atcttgacta
     4921 tgacaaagtt cttgcaaatt acaaaaaagt cttatctgaa ctagcaggcc tatatgtgaa
     4981 gaccctcgat gttatccatt tcatgcacga taaatatgct tatgaagcag gtcaaatggc
     5041 ccttcatgat acctatgtta agagaaatct agcaacaggt gtggctggtc tttcaatcgc
     5101 agctgactca ctttctgcaa tcaaatatgc aaaagtaaaa ccagttaggg atgaaaatgg
     5161 catagcaatc gactttgaaa cagaaggcga cttccctaaa tatggtaacg atgatgacag
     5221 agtagaccaa atcgctgttg atatcctaac ctatttctct aatgaactta agaaacacgc
     5281 tacctacaaa aatgctaaac taaccctatc tgcccttaca attacatcaa atgtaatgta
     5341 tggtaaaaag acaggtacaa caccagacgg cagaaaggca ggcgaaccat ttgctccagg
     5401 tgcaaaccca atgcacggta gggacgaatc aggtgctctt gcaagtctta actctgtagc
     5461 taaacttcct tatgaatgtg tatgtgaaga cggtatttca aacaccttct caatcgtacc
     5521 tgacgcttta ggcaaggaag atgaagtgag aatagataac cttgtaaaca tcatggacgg
     5581 atattttggc caagatgcct tccacctaaa tgtaaacgtc cttcaaagag aaaaactcct
     5641 agacgcttac cacaacccag acaagtatcc aaacctcact atcagagttt ctggctatgc
     5701 tgttcacttc aacagactta cagatgaaca aaagagagaa gttctagaaa gaaccttcca
     5761 caaccaccaa taagataagg aggccttatg gcaaaattac attcaattga aacaatgggc
     5821 ctggtagacg gaccagggat aaggacagtg ttcttccttt ctggttgccc actaagatgt
     5881 gtattttgcc acaatccaga cacccaatcc ctagactatg gtagggatgt aacggtagat
     5941 gagattgtaa aaagagccct aagaatgaaa ccctacttca aaaacggagg tggagtcacc
     6001 ctttcgggtg gcgagcctct ggcaagtggg gcttttgtgc ttgaaaccat aagagccctc
     6061 cacaaggaag ccatccatgt ggcagtggat acttcaggtg tgggtgatga aaaatattac
     6121 gatgatatag ccagagaagc cgacctaatt ctcttggata tcaaacatta tgatccctac
     6181 ttcttttatg aaataacaaa aaattaccaa gacaaactca taaaatttat ggaatcaatc
     6241 aaaaaaactg ataccagggt ctggataaga cacgtaatga tgccctttgt cacagatacc
     6301 aaagaggata tggatgggct tgttgacttt attaggccaa taaaggcaaa tattgataag
     6361 atagaaattc ttccctacca caagttggga gtgtgtaaat atgcagattt gggcaagcca
     6421 tacaggatta aaaacatgga ggccatggat aaggataagg caaaaaactt tgaaatttat
     6481 gctaacaata tgttaaaatc tttgtaggag caaattatga acgactacaa aaaagatgaa
     6541 aaaagttttt tggccttttt atccgatcaa gaattacaac gttttaagta cagaccccaa
     6601 gttttagcct acaggagggg agatatgata ttttcctttg gtgactcggc tgattttatg
     6661 tatataatcc tcgagggttt tataaaaata tccacctacc tttctgacgg cagggagcag
     6721 attttgtata tttacggcga gggagacttt gttggtgccc acaaccttct taccgaagag
     6781 gaatacatct atgaggcgag ggccttaacc aaggccaaac tcttgataat atcaaggatt
     6841 gacttcaata gtatcctcaa aaaaaataac aaagttctaa tcaaaatcct agaccaatcc
     6901 ttcaggagga ttaggagatc tgaagagctt atagacaggc tttcgaccat aaatgcagac
     6961 atgaaagtcg ccaaactcct cttggacttg gcagatgatg ttggcatagt caaaaaagac
     7021 ggagttttga ttacatccca ccttagccgt gaggaactgg ggtcttattc gggtgttgtg
     7081 agagaaaccc tttcgaggaa gttatcaaac tttgaaaaga tgggcttaat caagattatc
     7141 ggtaggaatg aaatcctaat aaccaatata agagcccttg aaaagatgac ctcataagca
     7201 acgactgttt aatttgtcga aaagtggggg gaatcttaca aacattaggc tcggtttttg
     7261 agtcaataaa tttgataata gcacgaatga aaagacttcc ttgtggagtc tttttttgtt
     7321 taatttgata aaaacttctc ttccggtatc atggtgggac ggaggaaata tgaataaaca
     7381 aacatttaag ataatgctcg cctatgttgg cgtcctcaca ggtgcaggac ttgcctcggg
     7441 ccaagagctt ttgcaatact ttgtctcgct tggaataaat ggacttgtcg gtataagcct
     7501 agtaggcatc ctacatatgg taatcggtgg gattttatta attctcggta gccactatct
     7561 ggcgaccgac cattccgatg tatttgacga aatcactaac aaatttattt caaaatttat
     7621 ggacatatcc ttgatattca cctgctttgt agttggtttt gtcatgcttg caggggcggg
     7681 gtctaaccta aaccaggcct ttggtctaaa tgtcaacgtt ggtagggtct tatgtgccct
     7741 tttaataatt gtcgttggca tgatggattt ttccaaggta agcaagataa taggatcatt
     7801 tacacccttt atcgtgggtt ttgtcctaat cgggtctgtc tacaccttta ttaaattcaa
     7861 gccagactgg caagccctaa atgccttcgc ggtaaaactt ccatcaaact ttgataatgt
     7921 aggctttgca gtcctaaatt attttggaat gtgcctaatg acagcagttt ccatgggcct
     7981 tgtactaggt ggagatgaat taagcacaga aaatgccggc aaaggtggcc taatgggagg
     8041 cgctattgtt ggaatcatgg gagtcttaat aaccttgacc ctcttaataa gagtcgaaga
     8101 agtatataat cttgacatac caatgcttta catcatagaa gatatcagtc caattctagg
     8161 atttgtcatg gctctggtag tatttgggat gatatttaat acaggaattt cactttttta
     8221 tgccctagca aggagatttt caaacgggga agaaagacga tttaaaatca tgcttgtaac
     8281 aatcacaggc gtaggcttta tcctttcctt cctaggcttt aagaaattag tttcgatatt
     8341 ttacccaata atcggctata ttggaatatt catgatggcc cttttagtct tcgcctactt
     8401 caaagaaaga tcagccatca gacgagaatc catgaaaaga ctgggaatca gacactacat
     8461 gagaaaaaaa ctcgatgacg acctagactt caccaaacaa gatgaagaaa gactaaacaa
     8521 actaatagac cgctcccaca tagacaacga ccaaatcgag gaaaagacag aagaaaccgt
     8581 ccaagaagcc atagacaacg acgaagaacc tcttactgac catggggaga attgagaaaa
     8641 gtgtccgaaa gggcactttt ttgttaaatc tttctcaatc tgggtataat agttagaagg
     8701 atctaaagga ggtgttttta ttaggtttta tataggatat ttttttgttt atgcctttat
     8761 tggtcggatt atggaggttt cttaccaggc tattaagact gggcgtttta ttaatagggg
     8821 gtttttgaat gggcctcttt gtccgattta cggttttggg gccttgggtg tgatttattt
     8881 tttgactgat atagcaaaga ccaataaatt atacttattt tttggatcga tttttatagc
     8941 cacatccctt gaacttgttg gggggtttct tttggagaag attttccaca agaaatggtg
     9001 ggattattct gatatgagat ttaatcttgg tggctatatt tgccttgaat tttcaattct
     9061 ttggggcctt gcttgctttg ttttgtatga ggctatccac cctttgattg taagattttt
     9121 tgccttttta aatccaaaat ttatttttta tgctaacata attttattgg caatttttgc
     9181 tgtggatatg gcacagacta ttctgaccct ggttggactt aataagaagt ttaaaaaact
     9241 ccaagctgca agcgaagata ttagagaagt ttctgatgat attggcaagc gtgtctacga
     9301 caggaccatg tctatcaagg agaagagaga agaaatcaaa ccaagggtta aggaacttga
     9361 ggcaaagaga aataaaatta ggatggatat agctaataaa tttgataaga tgagtgaaaa
     9421 acgacttata aaggcctttc caaatttaat agaagacctt gttgaaaaaa ttgacaaaga
     9481 tatagagaac atagaaaaat agggccctag gtcctatttt ttaatattta cttgctaaaa
     9541 ggagtataat ttaaacaata aaacttatac aatttattta ttggaggtaa ggatgcttga
     9601 taataaaggt tttgacctat gggcagatgg atatgacgaa agtgtcggtc tttgtgatga
     9661 ggaaaatacc tatccatttg cagcttataa ggatatttta aatgctattt ataaggatgt
     9721 cttaggagct gaagcaaaaa atgttttgga tataggtttt ggtacggcaa cgctcgcaag
     9781 tcgtttatat gacaagggcc taactatcta tggccaagat ttttctgagg aaatgatgaa
     9841 aatcgccaaa gaaaagatgc cgaatgcaaa tttatatgta ggtgactttg gaagagggct
     9901 ggtttcatcc ttgttaaacc ataagtatga tgcgatagtt gcgacatatt cacttcatca
     9961 tttaagtgat gaggataagg tttcattcat aaaaactttg ctttcccttt tgaatgttgg
    10021 tggaaagata tatattggag atgtggcttt caaaacaagg agagatttag aagctacaag
    10081 ggaaaaattt aagaacgaat gggatgagga tgaattttat tttgtctatg acgagctaaa
    10141 aaaccacttt agtaatctag acttcatcac atattcttat tgttcaggca tcttaactat
    10201 cacaaactaa acttagctaa gttttattat agtataagct tttctagagc caaggagagc
    10261 taggatttag caggcttcag tgggggagtt gtgaattgta aataaatttt ataaatgtaa
    10321 aatgatatta agtttcttaa aaaaggagtt atgatgaaaa ttatagtaat gggtatgggt
    10381 tatgttggtc tttcaaatgc agtcctactc gcccaaacaa atgaggttat aggccttgaa
    10441 attgaccaaa aaaaggttga tctaatcaat aataaaaaat cacccctaaa ggacgattac
    10501 ctaatagatt atctggccaa taaaaaattg aatcttatcg ctaaaacaag cggagaggag
    10561 gactttaagg attgtgacct tgccatcctt gccctaccaa caaactacga cgaagtggag
    10621 aaatttttcg acacttcctt cttagatgac gctataaaaa tgataaaatc tattagaaaa
    10681 gatttaccaa tcctaatcaa atcaactatt ccaatcggat atactgaggg aaaaaacaaa
    10741 gagtttaact gtgagaacat aattttctcg ccagaatttt taagggaggg cagggctctt
    10801 tacgattccc ttcacccttc aaggataatt gtctcagata agactgaaat cggcaaaaaa
    10861 attgctgacc tttataagtc tgaagcttta aataatcctg atgtgatttt gatgggaaga
    10921 agtgaggcag aggctgtaaa actttttgct aacacctacc ttgctatgag ggtgtcattt
    10981 tttaacgaac ttgataacta cgccatagct aagggccttg attccaaatc tattatagaa
    11041 ggtgtttctg ccgatccaag gataggtgac cactacaaca acccatcctt cggctatggt
    11101 ggctattgtc ttccaaaaga ttccaagcaa ctttacgcca attacgaaaa tattccgtca
    11161 gcccttttta agtcaattat cgattcaaat gaagtgagaa aagactttgt aagcgaggac
    11221 atccttgcta aaaatcctca aaccatcggc gtttataggt tggttatgaa aaagggttcg
    11281 gataatttta ggaagtctgc gatttttgat gtaataaata acctaaaatc caagggcgca
    11341 aaccttgtaa tttacgagcc aaacctagat ggcgatgact ttgaaggcat gaagttaatt
    11401 cgcaacttag aagactttaa gaaggttgac ctgataattg caaacagggt tgaagacgac
    11461 cttaaagatg taaaaaacaa actttatacc agagatttat ttgagaggga ctaaatgaca
    11521 gaaaagaaaa atgtgcccca agtccattcc aagctcagaa aatcatttat ttctgtgcca
    11581 gaagaaattt ataaggcaag tggcatcaaa atttttgata agaggataaa atccttgctt
    11641 ttcactaccg accttgccat aattagaaat tcaaatgctg actcaatcat ggcggtctat
    11701 ccttacacac cattaaattc catcactgag gccattattt ccatagcttc agttccatgt
    11761 tttatcggag ttggtggtgg cactacccaa ggcccaagat caaggtttgt ggcttattat
    11821 gcagaacttg caggtgccta cggggttgtg gtaaatggtc caattccaca cgaagatatt
    11881 agggaaattt caaaatttgt tgacatacct gttatagcta ctgtttcgtc tttgaaggat
    11941 gattacaagg cgaagattga agctggagca gaaattttaa atgtgtctgg tggtaaatat
    12001 acagccgatc tcgttcgcca tattagggca gatattgggg atgattttcc aataatagct
    12061 acaggtggca aggacggtga gtctatactt gagacaatta aagctggagc taatgccatt
    12121 tcctacactc caccatcttc atctgatgtt tttggctcaa tgatggatac ttacagaaat
    12181 gaggatatct gatgtatagt ggatatttta cagatgttgg aaatataaaa gtgggccacg
    12241 cccaagactt agaagggggc acaggcctta caatcatcat tccagattcc ggaaatactg
    12301 caggtgttga tgtgagaggt ggggcgccgg gcactcgtga gactgaccta ttaaacccta
    12361 taaaccaagt atctgaagta agttcgatta ttttatcggg aggctctgcc tacggccttg
    12421 aagcggcaag ccaccttatg aaaattctcg aaaaagaagg taggggcttt aatgtgggag
    12481 tcggggttgt gccaatcatt agccaggctg tcttattcga cttatcctac aaagattcca
    12541 aggcgagacc agatgcaaag atgactgaaa aagcctataa caatgctagg tatgaagata
    12601 agagtcaagg aatagttggc gctggcacag gtgccacagt tgccaaggca cttggaccag
    12661 accacttggt aaaatcaggt ctagggcaag cttctataaa aaaaggggac ttggtagtct
    12721 ctgctatagt tgctgtaaac gcctttggag atatttttga ctaccataag gctctccagc
    12781 ttgcagggcc aattgtggat gggaaaatgc ttaggactgt tgatatgatt gataaaatcc
    12841 taggatcttt tgctgacata aaaccagcca acacaacaat cggcgctgta gccaccaacg
    12901 ctactttcac caagacagag ctaacaaaaa tagcaggcat ggcccacgat ggctatgcaa
    12961 ggtcaataaa tcctgtgcat accctctttg acggcgatac aattttttca ttagcgacca
    13021 acaaagtgca agcaaatatc aatctcgtag gaacactcgc agcagaagcc atgtccatgg
    13081 cgattgcaaa tgcgatttac agctcgagag aaaaaaataa ttaagtttaa gactagttta
    13141 gctagtcttt tttgttgcta aagaaaagaa gcttatattt gccttcacat cttaaaacgt
    13201 agaataaaat attacttata aaattatgat caaggttaga aggatttgat ggttaagcta
    13261 gccgtttttt taattagaat ttaattaaaa ttctactaat actaaatttt ttttagaagc
    13321 gaagctaaaa tataaggggt gtaggcttta ggaatatgta aaaaacacgt ttttctaatg
    13381 attttttgct taatttagag tattaattac tttcctataa aaccttttca ttaacaaaaa
    13441 attatgatat aatgaaaaaa aatgataagc taaaaggtga taagttttgt catgtaaaat
    13501 aaaaatgata aattaatctc tacatatcca ataatatttt taattttact tgttaaatct
    13561 tatttttttg atatttatca ttttgtttgc gaatctaatt tttaaagtag aaatatgtaa
    13621 tagaaggggt ggttagaatg ttcacataag aaatccagct aattacaaag gacgatactg
    13681 tattattttt gaaaatttta ggagaattta tgaaatattt aaaagaattt tgttatatac
    13741 tttttttctt attgttgggc tttattgcta agaaactaac aggactacca attccagaac
    13801 cagtttttgg tatgattttc ttatttattg ctctttgcag caagttccta aaggtagacg
    13861 atattgggga aacatctgat tttctaacat caatcctagc ctttaccttc acaccacttg
    13921 gtgttgccct tatggttcaa tttgatgtga ttaaggataa tgctgtgaag attcttatag
    13981 ttatgacagt ttcttgccta ataaccatgg ctgttacagc aaaggttgta gaattagtac
    14041 aaaaagtgag gaaataatat gagtgaattt ttaaatacat atgtagcgga taatgatttt
    14101 tttgggatta tcctaagtat agtaatgttt agaattggga tggtaataaa taaaaaaacc
    14161 aaaatcgctg tcttaaaccc acttttactt gctattgttt tttgcataat cttcctaaaa
    14221 ttaactggaa tttcttatga aaacttcaac aagggtggca agtatatttc ttttatgatt
    14281 gccccaatca ctgttgccct agtagtaagc ctttacagaa atattgaaaa attaaaggcc
    14341 aacctcattc cgattttaat tggcgtaata gttggatcct ttgtggctat cctttcagct
    14401 tatcttttat caaagctttt tggttttgat agagatttga ccctttcaat gatgccacaa
    14461 tcagttacaa caccaatcgc taagtcattg acagaagaat atgtagccaa attcggtgct
    14521 gatgaagtaa ctatcaaaac ttttgcagct atcacagcta tcacagttat cctaagggga
    14581 actgtaggtg cgattgctgc tccaactgtg atgaaggtaa tgagagtaaa agaccctgtt
    14641 gcccaaggta ttggaattgg tacatctagc cacgctatgg gtacatcaaa ggctatcgaa
    14701 atgggtgaag ttgaaggagc catgagtggt ctatctatag cagtagctgg tatttgcact
    14761 gttgtattga tgccattatt tataattcta ttattctaat atttcccaag gtttaatatt
    14821 agatgactaa aaaaattttt atgtacacag gaaagggcgg ggttggcaag tcaacccttg
    14881 ccagctctac tgcccttatt tctgctaaaa aaaatataga aactatcttg ataagtatag
    14941 attcagccca tagtttatcc gatatttttt ctataaaaat aggaaatacc ttaacaaagg
    15001 tcagagatgg tctaactgca attgaatttg atagctcaaa gattttagaa gaagaatttc
    15061 caagcataaa ggcaagccta gctaacgagt ttaggaaggt tgatttttca aaaatctcct
    15121 acaattcaag ttttgatatg ccctttgttg tgaatatcct ttccttgctt aaaatccttg
    15181 atatatacga aaattacgac tttgaaaata tagttgtgga ttgtcctgct tcggcatcta
    15241 cctttgccta cttaaaaatt cctgagatgc ttagctggta tctggaaaaa ttttttggtg
    15301 ttgggaaggg tattattagg accttaaggc ctatatccaa gtataaatac cagattgatt
    15361 tgccggataa ggaagctttg gataagctgg aagttactta tcagaggttg aaaaaattag
    15421 aagatatctt gaagaataag actatttcga caataaggtt ggtaggactt gctgaaaaaa
    15481 tggtaattga agagagcaaa agagattttg cctacctaag tttatttgat tataatgtgg
    15541 atggattttt tgcaaacagg ttgttggcag atgaagatat cgattttatc aaaaaacgca
    15601 tccaaataca aaataaaagg cttgaggaga ttaaagtttg cttttataat ttgccaattt
    15661 ataagatagg tctaatgaat aaggacctaa atagtttggt tgatctagaa gattttgctg
    15721 atagtttaga ctttaaagat aatcttttag atataaggcc tttcaaagaa ggtcattact
    15781 ttgaaaaaat tccttatggg tacatcctta aaattaatat tccggctgtt gaggatgtgg
    15841 aagtttataa aaaaggttct gacataaata ttaagcttaa ggatataaaa aggataatta
    15901 gcctgccaaa tgtatgcata aattcagaga ttggcaagta ttattgtcag ggtgatgaac
    15961 tttttatcta cttagaaagt aaggaccaag aggagctatc tgtatgagaa ttattataaa
    16021 cactggcaag ggaggggttg gcaaaacaac catttctgcc cttacagcta taaatatttc
    16081 aaaaagatac aagaccttgg ttattagcag tgacctagcc cacagcttaa gtgatttgtt
    16141 agacataaaa ttagatgata cacctcgaca ggtttctaat aacttgtatg cgcttgagat
    16201 aaatgcaatt aaggagagca agaaggcttg gggcaatctt aatctttaca taagacaatt
    16261 ggtagaagaa aatgccttgg atgacattca attagatgaa ttgctgttat tgccaggttt
    16321 ggacgatgtg ttttcccttt taaaaatttt agagatttat aagagtggag aatttgaagt
    16381 ccttgttgtg gattgtggac ctagtggtga gactatttct ctcttgtcta cgggagaaaa
    16441 attcaagaat ttggcagatt ctttagtgcc tttagttaag agatttaacc gacttttcgg
    16501 tagtttt
//
