LOCUS       NC_004917.1            22720 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_004917.1 Helicobacter hepaticus ATCC 51449, complete sequence.
ACCESSION   NC_004917
VERSION     NC_004917.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:34:49
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 656042
            Orig. end    :: 678762
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22720
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[666042:668762]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12720
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..22720
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22720
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             545..1723
                     /locus_tag="ctg1_660"
                     /transl_table=11
                     /translation="MIIAIVVDSYKDRSNGTSMTAFRFARALIERGHCVRIITTNPTQE
                     ESNEQSSGEEFYFVKERYIPIVTEISHKQHMIFGSPDSHILESALKGCDIAHFYLPFAL
                     EIAGVHLCRKMKIPYISAFHLQPQHISYNMNMNFKWFNAYLFRRFYKAFYRYTHHIHCP
                     SQLMEEEIQKAGYGGKKFVISNGFQINRAQSCVKPFDDTFFHIISVGRFSKEKRQDILI
                     KAITQSKYANNIKLHLHGIGPKEQYLRKLCDKLLINPPEFGFIDNNILIEKLKCCHLYV
                     HSAEVESEAISCLEAVSIGLVPVIADSKISATTQFALDERSLFKTNNIADLSAKIDYWV
                     EHSKEREQMKEQYAKSASKYALEKSIDKIINMYEEAITDFTTNPILFKAINA"
     CDS             1850..2263
                     /locus_tag="ctg1_661"
                     /transl_table=11
                     /translation="MEQTLSIIKPDAVKKGVIGKIIDRFESNNLRICAMKKLQLTRCDA
                     EAFYAIHKERPFFKDLVDFMISGPVVVMVLEGNNAVMKNRDLMGATNPKEAEAGTIRAD
                     FAQSIDANAVHGSDSLENAKNEIAFFFSTREIC"
     CDS             2264..2617
                     /locus_tag="ctg1_662"
                     /transl_table=11
                     /translation="LKIAMRKISHTPKDIALNIEGVNLQAQLYRMDSQMLCLKGKIYGE
                     IELVCDNSGEEYIHKLENPLVLYISDGIWNAQSQSKKLDSFEVVEFFDGFIDLHYILES
                     EIESIRSDYHTKD"
     CDS             2632..2781
                     /locus_tag="ctg1_663"
                     /transl_table=11
                     /translation="MAVPKRRVSKTRAAKRRSHYKIALAKPIKDKDGSWKMPHHINKFT
                     GSYK"
     CDS             2803..3804
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FA_synthesis"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_664"
                     /sec_met_domain="FA_synthesis (E-value: 7.7e-119, bitscore:
                     393.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKIAIDVMGADNGVTPIVQGVIQALKSRDFNAVIIGDEAQIAPL
                     VPPYLQSRAQIVHCTDYIRMEESASAAAKRTQSSIFKTTELLKNGDVDALVSPGHSGAT
                     MSLATLKIGRIKGVSRPAICTTMPNTTDKPSIILDAGANTDCKPEYLVDFAIMGYEYAK
                     NVIGFENPRVGLLSNGEEDNKGNELTKATFKLLKEFSFFKGNVEGRDIFNGSVDVIVCD
                     GFSGNLVLKASEGVASAMSSVLKKDIKSCLCSMFGALFLRGVFKRLKKKMDHSEYGGAP
                     LLGVQKVVIISHGSANARAIECAIYQALNAIESNICSKLSDAFANKPSSAQQ"
     CDS             3814..4812
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiolase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ACP_syn_III"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ACP_syn_III_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_665"
                     /sec_met_domain="Thiolase_N (E-value: 7.4e-10, bitscore:
                     35.3, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III (E-value: 9.4e-32, bitscore:
                     105.5, seeds: 136, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III_C (E-value: 2.2e-33, bitscore:
                     111.1, seeds: 152, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKIYASLKSIASYIPPTCISNVDFEKTLDTNDEWITKRTGIKTR
                     YFALPSQQTSDLAYEAGKKAIERAGIEPKDIDAVIVATLSPDYLTMPSTACITSFKLGI
                     ENKAAFDISAACSGFVYLLSLAKSFIESGTYKQILIIGAEKTSSVLDFSDRSTCVLFGD
                     GAGACVIGSTNDEKAAILGVNVSANGRYQDFLCTPRVHATFGATQAQEKQSFIQMKGNE
                     TFKVAVKTLVSEVKEILNTHHINPQDVSFFIPHQANLRIINAVGENLNFTPEQIVVSIQ
                     KYGNTSAASIPMAMNDLYEEKKLKYGDLMLLDALGGGLTWGSALVHFGGTN"
     CDS             4893..7136
                     /locus_tag="ctg1_666"
                     /transl_table=11
                     /translation="MKEASFYIEQMTCQACSSGIERSLKRKSFCQDIQVHLLSKKAHIV
                     YDETQANLEDIFKLIAKMGYEPHLNDSTLDKRSTSKHTSFSLNALIESFDNRFLSTQTK
                     LIVSIIATIIVVVLSWSEMFIGISLPYTLHYTLLLVLSLAVMHMGRMFYLRGFKALFAR
                     NPNMDSLIAISTSSAFLYSLQGTFNAHFHTYFDSVCVIITLVLVGKSIEERSKKNALDS
                     ASLLLQLNQKTLQKIQLPNNATLDIQTLSNAPCRTVTAQDIQQGDILKVLPGEMIMVDS
                     IMIEGHSSIDTSAINGESLPLLAHKDDRLFSGSINLDGVLYVRAEKNAQQSTLAQILQL
                     VQKAQESKAPIASLADKVAAFFVPLVICLAAGAGVFWWGMRDFEFGLSIFIATLVISCP
                     CALGLATPMAILHAQAISNKMGVFFKDAKSFQTLSQITHIAFDKTGTLTQGLEIAQILS
                     FDKHLSQQEIFNLAYTLESTSTHIIAQAFHTHPMSANVTLYPIINAQNIIGSGIKGTIN
                     DCEYWLGNAHLLPPHLRGELENLPQDDKIILYLATNERILAQFALQDHIKSDALSTLAH
                     FREKNISFSLISGDNLLNTQKIAFALGITDFTALAKPQDKMRLLEQLNANNHKVLMVGD
                     GINDVPALAYAHTSIAFASPQDIATQSADITIYNQHLMSIYNAYSLAKASILNIKQNLV
                     FAFCYNIAFIPLAMGVLGGFGIFLHPMFCAFAMTCSSLSVVANAARLKAFKIL"
     CDS             7156..7368
                     /locus_tag="ctg1_667"
                     /transl_table=11
                     /translation="MTTTLSVSGMRCGKCVDKIEKFIGEIEGVSLIDVNLEKSQVKIEF
                     NAPATQELISEAILDAGFGIDENNS"
     CDS             7352..9067
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     277.4; E-value: 1.5e-84)"
                     /gene_kind="resistance"
                     /locus_tag="ctg1_668"
                     /transl_table=11
                     /translation="MRTILEFFKKFFPYIKGHKLSFAIAIIASLVVGLCTAGTAYLIDP
                     LLDTLSGKVPRANPFFSFDELAQNNTLTFAMMFMIIGTYLGKSLGTYVQAYFMNFIGQD
                     IVRQVRDRMLRHMLSLEMVFFNKMRNGELMARITNDIGIIRSAVSNYITEFIRESITII
                     GLVAIVIYQSPKYALIGLVIVPLALIPINLIIKKLKKYSRNIMEKNADITAKLHEIFNN
                     IEVIKASNGERLELKKFKLQNLTFLKISMKAVRVGELITPLMELLGAIMLALVVYMAII
                     DISKGELSVAQFSSFAGALLFIYTPLKRLVNLYGQMQSAIVASDRIFEILNQTQQIRDG
                     GIQLQAPINEIIFKDVHFRYNEETHALKGISMCFAKNKITALVGKSGSGKSSIINLLLR
                     LYEADSGEVLINSQNIKNYTQKSVRNNMAVVTQRIFIFNDSILHNVAYGSKIDEKKVIE
                     ALKFAHAWDFVQEMPQGIHTILDEFGSNLSGGQRQRIAIARAIYKNPEVLILDEATSAL
                     DSQTEEAIKESIEHLRHNKIIIIVAHRPSTIELADEVLHLQLGQIIKQETRSKK"
     CDS             9230..10000
                     /locus_tag="ctg1_669"
                     /transl_table=11
                     /translation="MREDKIIESYTGVTPQRKKSKIPAKLDFWQSATGLFLGLFMLAHL
                     LFVSSILISKEAMYKVTKFFEGSMIFGEAGEPRLVSVIVAIVIIALVVHAFLALRKFPI
                     NYKQFLALRVHKDLMKHGDTSYWAIQAATGFAIFFLAMPHVFIMLTQPENIGPSASSYR
                     FYHQDFYLLYALLLFAVEFHGSIGLYRLCIKWGWFEGLGIKALRAIKLALTAFCLILGI
                     ASYVAYMQIGHGLDSSYSIQEYRIIDEHTQGKGE"
     CDS             10001..11977
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 415.4; E-value:
                     9.7e-127)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_670"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.8e-125,
                     bitscore: 415.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-38,
                     bitscore: 128.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVYSDALIIGGGLAGLRASIAAKQAGLNTIVLSLVPVKRSHSA
                     AAQGGMQASLGNSVKSDGDNEDLHFADTVKGSDWGCDQNVARMFVTTAPKAIRQLAGFG
                     VPWTRIQKGDRPAVINGEKVTITEDDFRHGYIHSRDFGGTKKWRTCYTADATGHTMLYA
                     VANEAYKLGVDIQDRKEAISLIHQDGRCYGAVVRDLVTGELIAYVSKGTLLATGGYGRV
                     YRNTTNAVICEGTGAAIAMETGVAKLGNMEAVQFHPTPIVPSGILLTEGCRGDGGVLRD
                     VDGYRFMPDYEPEKKELASRDVVSRRMLEHIRNGKGVKSPYGDHLWLDISILGRAHVER
                     NLRDVQDICKTFAGIDPATPGVWAPVRPMQHYSMGGIRTDYRGETYLKGLFAAGEVACW
                     DLHGFNRLGGNSVSEAVVAGMIIGEYFTEYCQGANLDVQTTLLEKFVKKEEEYLASLLN
                     STGNEDVYVLKNAMKDIMDNDVGIFRDGKSLQEAVNKLEDLYKRSKNVRVQNKKLHNNP
                     ELEDAYRTPKMLKIALCVAKGALDRTESRGAHTREDYPKRDDANWLKRTLTSWEDPNQT
                     LPTVTYEDLDIMKMEIAPGFRGYGAKGMIIEHPNSAIRQAEIEKITQEIQAKGGDRYAL
                     QEALMPFNLQPQFKARNQRLGDK"
     CDS             11977..12720
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 105.4; E-value: 5.2e-33)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_671"
                     /sec_met_domain="Fer2_3 (E-value: 1.5e-31, bitscore: 105.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.7e-08, bitscore: 30.9,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0096, bitscore: 13.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATQQKGRTLTIRALKFDPQSAVSKPHFREYQVEEAHSMTVFIA
                     LGMIREQQDPDLSFDFVCRAGICGSCAMMINGRPRLACKTLTQDFPDGVITLMPLPAFK
                     LIKDLSVNTGEWFAGMTKRVESWIHTQHQPDISKLEVPIEPEVADEVFELDRCIECGCC
                     IASCATKVMREDFVGAAGMNRIVRFMIDPHDERTDEDYYELVGNDDGVFGCMSLIACHD
                     TCPKELPLQSKIAYLRRKMLSVGMK"
     CDS             12772..14334
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_672"
                     /sec_met_domain="PLDc_2 (E-value: 1.3e-22, bitscore: 76.9,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSIYSVFFSSTNIALLCLICLFIFAGCSSIVASTKDIKDPLALQ
                     SNPTPVFDPVLTAIGMPYQNKLKQNPTITGGMLVSDGLDAFLHRAYLARMAEKSIVLQT
                     YIYKNDLASRILMHEIWLAAQRGVIVKMLIDDNGLDSDFSDIIALNSHPNIEVKIFNPY
                     KNRSKILRYPEMVFDFNRINHRMHNKLFIVDDIALIIGGRNIADNYFDQNHHINFVDTD
                     VLFIGNVAMEGKKNFYEYWNFHRSIPVSLLKFKTPLKKLKSSMESLKANPEWAHYEEKI
                     NTLIKKYKNKSFEVFWGNAVFIADKPEKIQDPQAPKPIAKALAKILNFTYNNLYISAAY
                     FVPSKEGIKRFKTLIASGVDINILTNSLASTDSLVVYSAWERYRGTLIKEGANIYEYQY
                     QGRGKSKLRDKISKSKASLHSKSIVFDDSITWIGSFNLDPRSTHLNTECVVIFDNPKFA
                     KVFKADLMTDMESAWHVYNKNGKTLWEGDDESKTEIFTYPPDTGIWTRILKTLAKILPE
                     SQI"
     CDS             complement(14352..14723)
                     /locus_tag="ctg1_673"
                     /transl_table=11
                     /translation="MRLLKRVLWAVSIIILDIWGCTGDCKSCHQNLDYKNDIRHRPMLE
                     CKTCHTDEKMAQIDMGGCGEDCFLCHDVKKIQSPALAKEHSVIDACIQCHTQLSTSPIN
                     TGENVFQKSLKSFSNGLAP"
     CDS             complement(14725..14931)
                     /locus_tag="ctg1_674"
                     /transl_table=11
                     /translation="MSGHILLNGKDYEIDEQVTILSLIKKLNITHKAMAIAVNTQVVKK
                     PLWESYILQNGDEVEILDFVGGG"
     CDS             complement(14931..16295)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hexapep"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IspD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_675"
                     /sec_met_domain="Hexapep (E-value: 1.3e-05, bitscore: 21.5,
                     seeds: 216, tool: rule-based-clusters)"
                     /sec_met_domain="IspD (E-value: 4.2e-06, bitscore: 23.4,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVSVVILAAGAGTRMKSHIPKVLHKICGKEMLFYSIDEALKISD
                     DVHIVLFHQENVIKERLLCAYKQAYADGALHFHLQDHAHYPGTGGALMQGQNAGANAKK
                     PFCYQYDEILILNGDMPLVCSQTLKSLCQNKAQIVMSVLHLQNPDGYGRVVMESGVVQR
                     IIEQKDAKESELLIKDVNAGVYKIHKSILDLYLPQVGNANNQQEFYLTDVVFYAKENGI
                     EIAALEVKEEEFMGVNSKIQLACAQEIMLQRLREKAMEQGVIMNLPHTIYLESNVTFSG
                     ECIIEQGVQILGDSHISDSHIKAHSVIEQSIIESSDVGPLAHIRPKSHIKNTHIGNFVE
                     TKSSTLRGVKVGHLSYLGDCEIDEGSNIGAGVITCNYDGKAKHKTTIGKSVFVGSDVQL
                     IAPLNIESNVLIGAGSTITKDIEYGDLALSRVAQQNIKDGFFKFFSDKNEEKKEQ"
     CDS             16427..17191
                     /locus_tag="ctg1_676"
                     /transl_table=11
                     /translation="MLFTYAEPKLEPALPAPSSIPSVPSIPNNPILPSVDLSLTAPKEP
                     TELVATLNIVLIITLLVIAPSLVLVMTSFTRIVIVFAFLRTALGTQQSPPTQVLVSLAL
                     ILTFFIMEPVATKSYEVGIKPYAEKKISYDEAFERAIVPFKDFMIKNTREKDLALFFRI
                     RQLENPQSVNDVPLTVLLPAFMISELKTAFWIGFLLYLPFLVIDMVISSVLMAMGMMML
                     PPVMISLPFKILVFILVDGWNLLIGNLVQGFK"
     CDS             17203..18417
                     /locus_tag="ctg1_677"
                     /transl_table=11
                     /translation="MNCEHFGICGGCTNIQDYSTQLQAKHNLTLQEFQSFLDTKSKNFQ
                     YPTNPLAIEVFASPQEGFRARAEFRFSHVFQNKSGLDFAMNAFGYNHRVPIKKCPILLP
                     TLQDIMPLLLHYLNTYDLLNHKLYACNLLSSLQNEIIITLIYHKSLDSHWESLALKIQK
                     ELEYTLNTNIHIIGRSKNHKHILSNDIICEHLTLFANTPKERTYTFFKQESRFCQPNPF
                     INTQMLEFIVSALSSIYTPQTPCDMLELYCGSGNFTIPLASIFRHIFATEVVKSAITLL
                     QKNMAKNNIENIIPARLNAFESIQALRKERVFFRLKNIDLDAFAFDCVLIDPPRSGVGE
                     EEVLYFLQNFNTIIYVSCNPHTLLNDLRILSQSHYVMRFGLFDQFPHTYHRECIVILRK
                     SNKIL"
     CDS             complement(18420..19592)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 104.2; E-value: 2.3e-32)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_678"
                     /sec_met_domain="MFS_1 (E-value: 6.7e-31, bitscore: 104.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKFALNATSKTILVLALSSFCMGVTEFIIAGVLQDVKAYFGVDS
                     NQAGLLTTMYAVGVVIGAPLLSIPLSGFNRKLQLLLNLGVFALANFVIYISDNFILNVI
                     ARFIAGTQHGVFFVIATLTAIQVSSKEKESRNLALMVSGLTIALVSGVPLGTFIGQIFG
                     FKSIFLLICLCTLIAFISAIAFMPSHLQGCKTHINALFKAFLHIPLLKAYAITICTCGG
                     AFVLYTYVTDLLTQKSHFNEASIVYILLLYGIFAILGNLFGGRLADNKGSRRALQIVLF
                     LQIIFYALVSVSAHSQVFVVINLAIMGFLSFASIPALKVNAMNMARKYTPDSMDSSVSV
                     NEAAFNVGIALANQIGGLVVVAPFLGVSFNPLFASLFALPAFILVLRKME"
     CDS             complement(19621..20331)
                     /locus_tag="ctg1_679"
                     /transl_table=11
                     /translation="MGLRAYLAKKAQSKREIFLKKRLIVPNENYEVLGEEETDFMYERI
                     GFNVMPHWNILEIARKLPYIIYIADFDKVNHKAFQESMPQIFAKVLDKYALTNLKSYAQ
                     KEEQKAANEIIVLDWQHSCYAYYPKKPSGECFPYYCDGDYGYNPYSITYGENEIYNFYF
                     PTFYPNGEHFAFFKYDTKSNQVAFGMVGLFDFESRGKKTTITIFGEHFIEEMRYYDEKI
                     FGFEIIEMAGLLHK"
     CDS             20487..21323
                     /locus_tag="ctg1_680"
                     /transl_table=11
                     /translation="MKNIIYGVCLLCACVFSAYGEVIAGVAIRVNGHAITLYEIASLQS
                     HLKISKQAAIDMLINERLKDDEIERFKISIEDFKIDEEIALLAANANLSKDEFLRKATH
                     TMSLQEYRTQIKKQLQTKELMQRILASNISISSEDELLTYYTRHKKEFLIPSQVRVVRY
                     FSQTDNALQKAIQSPKQNIKGVQKVNETIALSSLNPQIAQVFIHTPNNEFTPVLTTGGN
                     GFVSFLVKERLGETPINFEEAKPLINQKIMAQKEQSIIAEHFNKIRSSANIVNLRE"
     CDS             21326..22411
                     /locus_tag="ctg1_681"
                     /transl_table=11
                     /translation="MLSYTDPLFGIIIFVSLIATAAFIDYWQNRYKEKKKKRSLKNLTK
                     SYEFAGLTQGVEEFLALSQNPIPTLQFIANAYIQSGNTQEAIKIYLSILENLDNSKESA
                     KSKIEILQQLGIAYYTAGFLQRAKNIFLEILKNYPRNPQVLIYLLKTYENLSEYKNAID
                     TLECIEEIYDSHSTPTIAQEQFFHTIALNKAYLHTLLLINQYAMPLSSKIQRLNEIKAK
                     EIKLEKIILVFFKSVSHSLFWEEINKSENIASLIDVLWDFERKNVPLEQITHPQILDIY
                     RAKGWIQDTKSCNIFELENMRILKQHSTLCIDFSFEYRCHSCKQVFPFENARCSHCGEL
                     LNTDVIYKIQKVDNETSYSLL"
ORIGIN
        1 atgcaagtaa aaataccttt attcaaaaag aatgcaaaaa taattttgtc atttcagata
       61 agcttgtcgc agggattggg ctagaggatt taatgattat tgatgaaaac gattgcctct
      121 taatagccaa aaaagggtat tctcaacaag tcaaagatat tgtggctttg ctaaaaacta
      181 cccaccctga acttactcaa attcacaaaa ctgctcatcg cccttgggga acttatacaa
      241 ttttattaga atctcaaaat tacaaaatca agcaaattgt cgttaagcca aagggcaaat
      301 tgagcttaca aaaacattat catcgtaatg aacattggat tattgtaagc ggttgtgcca
      361 taattacact tggagaatca caaaaattcc tcaaagcaaa tcaaagcact tatattccta
      421 tgggtgaggt gcatagactt gaaaatcccg gaatcctgcc acttgtactc attgaagtgc
      481 aaatgggaga atatttaggt gaagatgaca tcgtgcgttt gagcgatgat tatcagcgta
      541 aataatgatt atagccatag tcgtagatag ttataaagat agaagtaatg gcacttctat
      601 gacagccttt cgctttgcaa gagctttgat cgaaagagga cactgtgtgc gcataatcac
      661 aacaaatcct acacaagaag aaagcaatga acaaagtagc ggtgaagagt tttattttgt
      721 caaagaaaga tatattccaa tcgttacaga aatctctcat aaacaacata tgatttttgg
      781 ttcaccagat tctcacattt tagaatctgc ccttaaaggt tgtgatattg cacattttta
      841 tttacctttt gcattagaaa ttgcaggtgt tcatttgtgc agaaagatga agattcccta
      901 tataagtgct tttcatctcc aacctcaaca tatcagttat aatatgaata tgaactttaa
      961 atggtttaat gcttatcttt ttaggagatt ctataaagcc ttttatcgtt acacacatca
     1021 tatccactgc ccaagtcagc ttatggaaga agaaatacaa aaggcagggt atggtgggaa
     1081 aaagtttgtt ataagcaatg gattccaaat taatagagcg caatcttgtg tgaagccatt
     1141 tgatgataca ttttttcata ttatttcagt gggaagattc tctaaagaaa agcggcagga
     1201 tattttgata aaagctatta ctcaaagtaa atatgcaaac aatatcaaat tacatctaca
     1261 cggaattgga ccaaaagagc aatatctgcg caaactctgc gataaacttt taatcaatcc
     1321 gcctgaattt ggttttattg ataataatat actcattgaa aaacttaaat gttgccattt
     1381 gtatgtgcat tctgcggaag ttgaaagcga ggctatttct tgcctagagg cagtttctat
     1441 tggattagtt cctgttattg ctgattctaa aataagtgct actacacaat ttgctcttga
     1501 tgaaagaagc ttatttaaaa caaataatat agcggattta agcgcaaaaa ttgactattg
     1561 ggtagaacac tctaaagaac gagagcagat gaaagagcaa tatgccaaaa gtgcatcaaa
     1621 atatgcactt gagaaaagta ttgataaaat cattaatatg tatgaagaag ctatcaccga
     1681 ttttacgaca aatcctatat tatttaaagc cattaacgct tgataaacgt tacactctta
     1741 aaattatttt ttatttctac ataaatattt atattaaagc aagttttttt tagataaaat
     1801 ttgaggtttt tagcatttgt atccacatac tattagagaa aggaaaatta tggagcaaac
     1861 actctcaatt attaagcccg atgctgtcaa aaaaggtgtg attggcaaaa ttatagaccg
     1921 ctttgaaagc aataatctcc gcatttgtgc aatgaagaaa cttcaactta ctcgttgcga
     1981 tgcagaagct ttttatgcta ttcataaaga acgaccattt tttaaggatt tggttgattt
     2041 tatgataagc ggaccagtgg ttgtgatggt gcttgaaggc aataatgccg taatgaaaaa
     2101 tcgtgatctt atgggtgcaa caaacccaaa agaagcagaa gctggcacga ttcgtgcaga
     2161 ttttgctcaa agcattgatg caaatgctgt gcacggaagt gatagtcttg aaaatgcaaa
     2221 aaatgaaatt gcttttttct ttagcacaag ggagatttgc taattgaaaa ttgcgatgcg
     2281 aaaaatctcc catactccta aagatattgc ccttaatatt gagggtgtga atttacaagc
     2341 gcagctttat cgtatggatt ctcaaatgct gtgcctcaaa ggcaaaatct acggggaaat
     2401 agagcttgtt tgcgataata gtggagaaga gtatattcac aaacttgaaa atcctttggt
     2461 tttgtatatt tcagatggta tctggaatgc acaaagccaa agcaaaaagc ttgatagttt
     2521 tgaagttgtt gagttttttg atggctttat tgatttacat tatattttag aaagtgaaat
     2581 tgaatctata cgaagcgatt atcacaccaa agactaattt aaggagtaga aatggcagtt
     2641 cctaaaagac gcgtaagcaa aacccgagca gcaaaaagac gctcacacta caaaatagct
     2701 cttgcaaaac ccatcaaaga taaagatgga agctggaaaa tgcctcatca tattaataaa
     2761 tttacaggta gctacaagta atttataact caaggagtga agatgctaaa aatagccatt
     2821 gatgttatgg gtgcggataa tggggtaact cctatcgttc aaggagttat acaggcatta
     2881 aaatcacgtg attttaatgc tgtcattatc ggtgatgagg cgcaaatcgc tcctcttgtc
     2941 cccccatatc ttcaatcgcg cgcacaaatc gtgcattgca cagattatat tcgtatggaa
     3001 gaatctgcat ctgcagcggc aaaacgcaca caatcttcta tttttaaaac caccgaactt
     3061 cttaaaaatg gagatgtaga tgcacttgtc tcacctggac atagtggagc aacaatgagc
     3121 cttgctacac ttaaaattgg acgcatcaaa ggtgtatcac gccctgcaat atgcactact
     3181 atgccaaata ctactgataa accgagtatt atccttgatg caggagcaaa tacagactgc
     3241 aaacctgaat acctcgtaga ttttgccatt atgggttatg aatatgcaaa aaatgttata
     3301 ggatttgaga atccgcgcgt agggctttta tctaatggtg aagaagataa taaaggaaat
     3361 gagcttacca aagctacctt caaactctta aaagaattta gtttctttaa aggcaatgtt
     3421 gaaggacgtg atatttttaa tggaagtgtt gatgttattg tatgtgatgg attcagtggg
     3481 aatctcgtgc taaaggcaag tgaaggggta gcgagtgcta tgtcatcggt gctgaaaaaa
     3541 gatattaaat cctgcctatg ttcaatgttt ggcgcacttt tcttacgcgg agtattcaaa
     3601 cgattaaaga aaaaaatgga ccatagtgaa tatggtggtg cccctctact cggtgtgcaa
     3661 aaagttgtca tcattagtca cggaagtgct aatgcgcgcg ctattgaatg cgctatttat
     3721 caagcgctta atgccataga atctaatata tgttccaagc tctctgatgc ttttgcaaat
     3781 aaaccttcga gcgctcaaca ataaggattc tctatgggca aaatatatgc ttcacttaaa
     3841 tcaattgctt cttatatccc tcccacctgc ataagcaatg ttgattttga aaaaacactt
     3901 gatacaaatg atgagtggat taccaaacgc acaggtatta aaacgcgtta ttttgccttg
     3961 ccttcacaac aaacaagtga ccttgcttat gaagcaggta aaaaagcaat agaacgcgca
     4021 ggcatcgaac caaaagatat tgatgcagta atcgtagcaa ctctaagccc tgattatctc
     4081 acaatgccta gcactgcttg tattacttcc tttaaactcg gtattgaaaa taaagccgcc
     4141 tttgatatta gtgcggcgtg tagtggattt gtttatcttc tctctcttgc taaatctttt
     4201 atagaatccg gcacttataa gcaaatcctc atcattggtg cagaaaaaac aagttctgtt
     4261 cttgatttta gcgatagaag cacttgtgtt ctttttggtg atggggctgg agcgtgtgtt
     4321 ataggtagca caaatgacga gaaagcagct atcttgggcg tgaatgtaag tgcaaatgga
     4381 cgatatcaag actttctttg cactccacgt gttcatgcaa cctttggcgc tactcaagca
     4441 caagaaaagc aatcatttat tcaaatgaaa ggcaatgaaa cctttaaagt tgctgtgaaa
     4501 acgcttgtat cagaagtaaa agagattcta aatacccatc acataaaccc tcaagatgta
     4561 tcatttttta ttcctcatca agcaaattta cgtattatta atgcagtggg agagaatcta
     4621 aacttcactc cagaacaaat cgttgtaagc atacaaaaat atggtaatac ttccgcagcc
     4681 tctattccta tggcaatgaa tgacctttac gaagaaaaaa agcttaaata tggggattta
     4741 atgctactag atgcccttgg tggtgggctt acttggggtt cagcacttgt gcactttggt
     4801 ggcacaaact aggcttttta aatattcttt tgcctttcat tttttttttt tttgttagaa
     4861 tgtcgccaaa atatttcaaa ggatataacg caatgaaaga ggcttctttt tatattgaac
     4921 aaatgacttg tcaagcttgt tctagtggga ttgagcgtag tctaaagcgt aaaagttttt
     4981 gccaagacat acaagtgcat cttttaagta aaaaagccca tattgtatat gatgaaacgc
     5041 aagcaaacct tgaagatatt tttaaactca tagccaaaat gggttatgag cctcatttaa
     5101 atgattctac gcttgataaa cgctctacct caaaacacac ttcattttca ctcaatgctc
     5161 ttatagaatc ttttgataat cgtttcttat ctactcaaac caaactcatt gtaagcataa
     5221 tcgccacaat tatagttgta gtgctctctt ggagtgaaat gtttataggc ataagtctgc
     5281 catatacact tcattacacg cttttacttg ttttaagctt ggcagttatg catatgggaa
     5341 gaatgtttta tttgcgtgga tttaaagcac tttttgcgcg aaatcccaat atggattctc
     5401 tgattgccat aagcacttct agtgcatttt tatacagctt acaaggcaca tttaatgcac
     5461 actttcatac atactttgat agcgtatgcg taattatcac ccttgtgctt gttggaaaat
     5521 ctattgaaga acgctccaaa aaaaatgcat tagatagtgc ctcgctactt ttgcagctta
     5581 accaaaaaac gctccaaaaa attcaactcc caaataatgc cacacttgat attcaaaccc
     5641 tatcaaatgc accttgcagg acagttactg cacaagatat tcaacaagga gatatactta
     5701 aagtcttacc tggtgaaatg attatggtag attctataat gatagaggga cattcaagca
     5761 tagatacatc tgctattaat ggtgaatcac tccctctttt agctcataaa gatgatagac
     5821 ttttttcagg gagcataaac cttgatggcg tgctgtatgt gcgtgcagaa aaaaatgcac
     5881 agcaatctac tcttgcacag attctacaac ttgtgcaaaa agctcaagaa agtaaagcac
     5941 ctatcgcctc acttgcggat aaggtggcag cattttttgt gccgcttgta atatgtttgg
     6001 cagcaggtgc tggtgtattt tggtggggta tgagagattt tgaatttggg cttagtattt
     6061 ttatcgctac tcttgttatt tcttgcccgt gcgcacttgg gcttgctaca ccaatggcga
     6121 ttctccacgc acaagctatt tcaaataaaa tgggcgtttt ttttaaagat gctaaaagct
     6181 ttcaaacact cagtcaaatc acacatattg catttgataa aacaggcaca ctcactcaag
     6241 gactggaaat agcacagatt ctctcttttg ataagcactt gagccaacaa gaaattttta
     6301 atctcgccta cactttagaa tccacaagca cacatattat tgcccaagct tttcacactc
     6361 accctatgag tgcaaatgtt acgctttacc ccattataaa tgcacaaaat atcataggca
     6421 gcggtattaa aggcactatt aatgattgtg aatattggct tggtaatgcc catttgcttc
     6481 caccacatct tagaggtgag cttgaaaatc tcccgcaaga tgataaaatc atactttatc
     6541 ttgctacaaa tgagcgcatt ttggcacaat ttgcattaca agaccatatc aaatccgatg
     6601 cactttccac ccttgcacat tttagagaaa aaaatataag ctttagtctt ataagtgggg
     6661 ataatctcct caatacacaa aaaattgcct ttgctctagg tattacagat tttaccgcct
     6721 tagcaaaacc tcaagataaa atgcgcctcc ttgaacagct taatgcaaac aatcacaaag
     6781 ttcttatggt tggcgatggg attaatgatg tgcctgctct tgcttatgca catacttcca
     6841 ttgcttttgc ctcgcctcaa gatattgcta cacaaagtgc cgatattact atttacaatc
     6901 aacatttaat gagtatttat aacgcatact ctcttgcaaa agccagtatt ttaaatataa
     6961 aacagaatct tgttttcgct ttttgctata atattgcttt tattcctcta gcaatgggtg
     7021 tattaggggg atttggcata ttcttacacc cgatgttttg cgcatttgca atgacctgct
     7081 caagcctaag tgtcgttgcc aatgctgcaa gattaaaagc atttaaaatt ttataaaatc
     7141 tcaaaaggag atgaaatgac aacgactcta tcagtaagtg gtatgcgctg tgggaaatgt
     7201 gtagataaaa ttgaaaaatt tatcggagaa atagaaggcg taagccttat tgatgtaaat
     7261 ttggaaaaaa gccaagttaa aatagaattt aatgcccctg ctacgcaaga gcttatttca
     7321 gaagctatcc ttgatgcagg atttggaata gatgagaaca attcttgaat tttttaaaaa
     7381 gttttttcct tatatcaaag gacataaact ttcttttgca atcgccatta ttgcttcact
     7441 tgttgtagga ttatgcacgg ctggaactgc ttatcttatt gaccctttgc ttgatacact
     7501 ctctggcaaa gttccacgtg ctaatccatt cttcagcttt gatgagttag ctcaaaataa
     7561 tacattaaca tttgcgatga tgtttatgat tattggcact tatttgggaa aatctcttgg
     7621 cacttatgtg caagcttatt ttatgaattt tattggacaa gatatcgtgc gacaagtgcg
     7681 tgatagaatg cttagacata tgctttcgct tgaaatggtg ttttttaata aaatgcgtaa
     7741 tggtgagctt atggcgagaa tcacgaatga tattggtatc attcgttcag ccgtttcaaa
     7801 ctatattaca gaatttatcc gagaaagcat tacaattatt gggcttgtag cgattgtcat
     7861 ttatcaaagt cccaaatatg cactcattgg gttagttatt gtgcccttag ctctcatacc
     7921 tatcaatctg attatcaaaa aacttaaaaa atattcacgc aatataatgg aaaaaaatgc
     7981 agatattacc gctaaacttc acgaaatctt caataatata gaagtcatta aagcgagtaa
     8041 tggggagcga ttggagctta aaaaatttaa acttcaaaat ctcacttttc ttaaaatcag
     8101 tatgaaagct gtgcgagtag gagaattaat tacccctctt atggagcttt taggggctat
     8161 tatgcttgca ttggtcgtat atatggcaat tattgatatt tccaaaggag aacttagtgt
     8221 agcacaattc tcatctttcg caggtgcgtt gctttttatc tacacaccac taaagagact
     8281 tgttaatctc tatggacaaa tgcaatctgc cattgttgca agtgatagaa tctttgagat
     8341 tctcaatcaa actcaacaaa tccgtgatgg tgggatacaa ctccaagccc caataaatga
     8401 aattattttt aaagatgtgc attttcgtta taacgaagaa acccacgcac ttaagggcat
     8461 aagtatgtgc tttgcaaaaa ataaaatcac tgctcttgta ggtaaaagtg gaagtggaaa
     8521 aagctcaatt atcaatttgc ttttgcgtct ttatgaagcc gatagtggag aggtgcttat
     8581 caacagccaa aacattaaaa actatacaca aaaaagtgtg cgcaataata tggcagtagt
     8641 tacacaaaga atttttatat ttaatgatag tattttacat aatgttgctt atggtagcaa
     8701 aatagatgaa aaaaaagtca ttgaagctct caaatttgct cacgcgtggg attttgtgca
     8761 agaaatgcct caaggaatac atactatcct tgatgaattt ggctcaaatc ttagtggcgg
     8821 gcaacgtcaa agaattgcca ttgcacgcgc aatttataag aatcctgaag tgcttatcct
     8881 tgatgaagct acttctgcac ttgattcaca aactgaagag gcaattaaag aaagtataga
     8941 gcatctaagg cataataaaa ttattatcat cgtagctcac cgcccaagca caattgaact
     9001 tgctgatgaa gtcttacatt tacaactagg gcagattatc aaacaagaaa ctcgctctaa
     9061 aaaataggat agacatctta agattctcaa aatggcataa aaaaacttta atcaatattt
     9121 tcctataatg tagcttagcc tttttaaaat gctactaagt agttttggga taaaagctcc
     9181 tagagtgctt gtgtaagcta tagaggtcaa actacaaaca ggaggtttca tgcgagagga
     9241 taaaataatt gaaagctaca caggggtaac acctcaaaga aaaaagagta aaatccctgc
     9301 caaacttgat ttttggcaaa gtgcaacagg cctattctta gggttgttta tgttggcaca
     9361 tttacttttt gtatcaagta tcttaatcag caaagaagcg atgtataaag ttacaaaatt
     9421 ctttgagggc agtatgattt ttggtgaggc aggcgagcca cgtcttgttt ctgttattgt
     9481 ggctattgtc attattgctc ttgtagtgca tgcgtttttg gcgttgagaa aattcccgat
     9541 taactacaaa caatttctcg ccttacgtgt tcataaagat ttaatgaagc acggggatac
     9601 aagttattgg gcaattcaag cagcgacagg ctttgctatt ttctttttgg caatgccaca
     9661 cgtattcata atgcttacac aacctgaaaa tatcggtcca agtgcaagtt catatagatt
     9721 ctatcaccaa gatttctatt tgctttatgc acttttactt tttgctgttg aatttcacgg
     9781 ctctattgga ctttatcggc tttgtattaa atggggctgg tttgaagggc ttggaatcaa
     9841 agcattacgt gctattaagc tagctctcac agcattctgc cttatacttg gtattgcttc
     9901 atatgtggcg tatatgcaaa ttggacacgg actagatagt agctacagta ttcaggaata
     9961 tagaataatc gatgagcaca cacaagggaa aggagagtaa atgaaagtag tatattcaga
    10021 tgcactgatt attggcggtg gtttagcagg acttcgtgct tctattgcag caaaacaggc
    10081 agggcttaac accattgtgc tttctcttgt gccagtcaaa agaagccatt cagcggctgc
    10141 tcaaggtggt atgcaagcaa gtctaggtaa ttctgtaaaa agtgatggtg ataatgaaga
    10201 tctacacttt gcagacacgg taaaaggaag tgattggggt tgtgatcaaa atgtagcaag
    10261 aatgtttgtt actaccgcac caaaagcaat tcgccaacta gcaggttttg gggtgccttg
    10321 gacaagaatc caaaaaggcg accgccctgc agttattaac ggcgaaaaag taacaattac
    10381 agaagatgat tttagacacg gttatattca ttcacgcgat tttggtggaa caaaaaaatg
    10441 gcgaacttgt tataccgccg atgctactgg acatacaatg ctttatgcag tagcaaacga
    10501 agcttacaaa ctcggtgtag atattcaaga taggaaagag gctatctctc ttatccatca
    10561 agatgggaga tgttatggag ccgtagtgcg tgatttggta acaggagaac ttatagctta
    10621 tgtatctaaa ggcactttac tcgctacagg aggctatggt agagtatatc gcaacactac
    10681 aaatgccgtt atctgtgaag gaacaggtgc agctattgca atggaaacag gcgtagcaaa
    10741 acttgggaat atggaagctg tgcagtttca ccctactccg attgtgccaa gtggaatcct
    10801 ccttacagaa ggttgtcgtg gcgatggtgg tgttctacgt gatgttgatg gctaccgctt
    10861 tatgcctgat tatgagccag agaaaaaaga acttgcaagt cgtgatgttg tctcaagaag
    10921 aatgcttgaa catatccgca atggtaaagg cgtaaaatct ccttatggcg accacttatg
    10981 gcttgatatc tctatcttag gacgtgctca cgtagagaga aacttgcgtg atgtgcaaga
    11041 tatttgtaaa acatttgcag gaattgaccc tgcaacaccg ggtgtttggg ctcccgtgcg
    11101 accaatgcag cactactcta tgggcggtat ccgtacagat tatagaggag aaacttacct
    11161 taaagggcta tttgctgctg gtgaagtagc ttgttgggac ctacacggat tcaatcgtct
    11221 tggcggaaac tctgtaagcg aagctgtagt agctggtatg attattggag aatactttac
    11281 agaatactgc caaggagcaa accttgatgt ccaaacaacc ttgcttgaaa aatttgtcaa
    11341 aaaagaagaa gaatatctcg cttcattgct taatagcaca ggaaatgaag atgtctatgt
    11401 gcttaaaaat gctatgaaag acattatgga taatgatgtg ggaatcttcc gtgatggcaa
    11461 aagtttgcaa gaggctgtga ataaacttga agatctctat aaacgcagta agaatgttcg
    11521 tgtgcaaaac aaaaaacttc ataacaatcc cgagcttgaa gatgcttacc gcacaccaaa
    11581 aatgcttaaa attgcattat gtgttgcaaa aggtgcactt gatagaacag aatctcgtgg
    11641 tgcacataca cgcgaagatt atccaaaacg tgatgatgcg aattggttaa aacgtacact
    11701 tacaagctgg gaagacccaa atcaaacatt accaacggtt acttatgaag atttggatat
    11761 tatgaaaatg gaaattgcac ccggcttccg tggctatggc gcaaaaggta tgattattga
    11821 acatccaaat agtgctattc gccaagctga gattgagaaa attacacaag agattcaagc
    11881 aaagggcggt gatagatatg ccttgcaaga agccttgatg cctttcaatc tccaaccaca
    11941 atttaaagca agaaaccaac gactaggaga taagtaatga gtgcaacaca acaaaaagga
    12001 agaacactaa ctattcgagc attaaagttt gacccacaaa gtgcagtgtc gaaaccacat
    12061 tttcgtgagt atcaggttga agaagctcat tcaatgacag tttttattgc attgggtatg
    12121 attagagagc aacaagaccc tgatttaagc tttgattttg tatgtcgtgc tggtatctgc
    12181 ggaagctgtg caatgatgat taacggacgt ccaagacttg cgtgtaaaac acttactcaa
    12241 gacttccctg atggtgtcat tacccttatg cctctccctg catttaaact tatcaaagat
    12301 ttaagcgtaa atacaggcga atggtttgca ggtatgacaa aacgagtaga aagctggata
    12361 catactcaac atcagcccga tatttctaaa cttgaagtgc ctattgaacc tgaagtagct
    12421 gatgaagttt ttgaacttga tagatgtatt gagtgtggct gttgtattgc aagctgtgca
    12481 acaaaagtta tgcgcgaaga ttttgttggt gcagctggaa tgaatcggat tgtgcgattt
    12541 atgattgacc cgcacgatga gcgcactgat gaggattatt atgagcttgt aggtaacgat
    12601 gatggtgtat ttggttgtat gagtcttatt gcttgccacg atacttgccc aaaagaactt
    12661 cctctacaga gcaaaattgc ttatttgcgc cgcaaaatgc ttagtgtagg tatgaaataa
    12721 cacgatcttt ctaccctttt acttaaaaag ggtagattct aaagaaacat aatgcaatct
    12781 atttattctg tctttttttc atcaacaaat attgctttgc tttgtcttat atgtcttttt
    12841 atctttgctg gttgttcttc tattgtcgct tctaccaaag acattaaaga cccacttgca
    12901 cttcaatcaa atccaacacc tgtttttgac cctgtgctca ctgctattgg tatgccttat
    12961 cagaataaac ttaaacaaaa cccaactatt acgggaggaa tgctcgtaag tgatgggtta
    13021 gacgcatttt tgcatcgcgc ttatctcgct cgtatggcag aaaaaagcat tgttttacaa
    13081 acttatattt ataaaaatga cctcgcttca cgtattctta tgcacgagat ttggcttgct
    13141 gcacaaagag gggtgattgt taaaatgctc attgatgata atggattaga ttctgatttt
    13201 tcagatatta ttgctcttaa ttctcaccca aatattgaag taaaaatctt caacccctat
    13261 aaaaatcgct caaaaatcct acgttatcca gaaatggtgt ttgattttaa tcgcattaat
    13321 catcgtatgc acaataaact ctttattgta gatgatattg cccttatcat tggtggacga
    13381 aatatcgcag ataattattt tgaccaaaat catcatatta attttgttga taccgatgtg
    13441 ctttttattg gtaatgtagc aatggagggc aaaaaaaatt tttatgaata ttggaatttt
    13501 catcgctcta ttcctgtttc acttcttaaa ttcaaaacgc cacttaaaaa acttaaatcc
    13561 tctatggaaa gtcttaaagc gaatcctgag tgggcacatt atgaggaaaa aatcaatacc
    13621 cttattaaaa aatacaaaaa caaatctttt gaggtatttt ggggcaacgc cgtgtttatt
    13681 gctgataaac cagaaaaaat tcaagaccca caagcgccaa aacccattgc caaagcactt
    13741 gcaaagattc tcaactttac atataacaat ctttatattt ctgccgccta ttttgtgcca
    13801 agcaaagagg gtataaaacg ttttaaaacc ttgattgctt cgggtgtgga tattaatatt
    13861 cttacaaatt ctcttgcctc tacggattct cttgtcgtat atagtgcgtg ggaacgttat
    13921 cgtggcactc ttattaaaga gggtgcaaat atatatgaat atcaatatca aggtagaggt
    13981 aaatcaaagt tacgtgataa aatatcaaag tccaaagctt ctttgcatag taaaagcatt
    14041 gtatttgatg attctattac ttggattggg agttttaatc ttgacccacg ttcaactcat
    14101 ctcaatactg aatgcgttgt tatctttgat aatcctaaat ttgcaaaagt ctttaaggct
    14161 gatttgatga cagatatgga aagtgcgtgg cacgtatata ataaaaatgg aaaaacgctt
    14221 tgggagggag atgatgaaag caagacagag atttttacct atcctcctga tacagggatt
    14281 tggacaagga ttctaaaaac acttgcaaaa attctccctg aaagccaaat ttaaaatctc
    14341 tgcatctgca attagggcgc caatccgtta ctgaaacttt taagactttt ttgaaaaaca
    14401 ttctctcctg tattaatagg tgaggtagaa agctgcgtat gacactgaat acaagcatca
    14461 ataacactat gttctttagc aagtgctgga gattgaatct tcttcacatc gtggcacaaa
    14521 aaacaatcct ctccacagcc acccatatca atttgtgcca ttttttcatc agtatggcaa
    14581 gtcttacatt caagcatagg acgatgtctt atatcatttt tataatcaag attctgatgg
    14641 cacgatttac aatctcctgt gcagccccat atatctaata ttataatact cactgcccat
    14701 agcactctct taagcaatct cattttatcc accaccaaca aaatctaaaa tctccacttc
    14761 atcaccattt tgtaatatat agctttccca taaaggcttt tttacaacct gtgtattaac
    14821 tgcaatcgcc attgccttat gggtaatatt caactttttt ataagcgata gaatcgttac
    14881 ttgctcatct atctcatagt ccttgccatt caataatata tgcccactca ttactgctcc
    14941 tttttctctt catttttgtc agaaaaaaat ttaaaaaacc catctttaat attttgttgt
    15001 gcaacacgtg aaagtgctaa atctccatat tcaatgtctt ttgtaatagt gcttcctgca
    15061 cctataagca catttgattc tatgtttaaa ggtgcgatga gttgcacatc acttcctaca
    15121 aacacacttt tgccaatagt cgtcttatgt tttgccttac catcgtaatt acaagtaatc
    15181 actcccgcac caatattgct tccctcatct atttcgcaat ctccaagata actcaaatga
    15241 cccactttca caccgcgcaa ggtgcttgat tttgtttcaa caaaattgcc aatatgagta
    15301 tttttgatat gactcttagg acggatatgc gccaaaggtc ctacatcact tgattctata
    15361 atgctctgtt caatcacact atgcgcttta atgtgagaat cactaatatg agaatcccct
    15421 aatatctgca caccctgctc tataatgcac tccccactaa aagtaacatt agattctaga
    15481 taaatagtat gaggcaagtt cataatcaca ccctgctcca ttgccttctc acgcaatctt
    15541 tgaagcataa tctcttgagc acaggcaagc tgaatcttag agttcacccc cataaattcc
    15601 tcttctttta cctccaatgc agctatttct atgccatttt cttttgcata aaaaactaca
    15661 tcggtaagat aaaattcttg ctgattattg gcatttccca cttgaggcaa gtaaagatca
    15721 aggattgatt tgtggatttt ataaacacct gcatttacat cttttatcaa aagctcggat
    15781 tcttttgcat ctttttgctc aataattctt tgcactacgc cagattccat cactacacgt
    15841 ccatagccat ctggattttg aagatgcaag acactcatta caatttgtgc tttgttttgg
    15901 cataaagact tgagagtttg tgaacacact aaaggcatat caccattaag aataagaatc
    15961 tcatcatatt gataacaaaa aggcttttta gcgtttgcac ctgcattttg tccttgcatt
    16021 agcgcaccac ctgtcccggg ataatgagcg tggtcttgga gatgaaaatg caatgcccca
    16081 tcagcataag cctgtttata tgcacaaagt aagcgctctt tgattacatt ttcttgatga
    16141 aaaagcacaa tatgcacatc atcacttatt tttaatgcct catcaatgga gtaaaacaac
    16201 atttctttgc cacaaatttt atgtaatact ttaggaatat gcgatttcat acgcgtccct
    16261 gctcctgcgg ctaaaatcac cactgataca ttcataaatt actccttcat ttatattgaa
    16321 ttggcttaat ttatataatt ttaacacact aaatcctata atacgccctt gagtttcaat
    16381 tttggagtga tttttgaaaa aaatattttg cctgcttagt ttatgtatgc tttttactta
    16441 tgcagagcca aaacttgagc ccgcacttcc tgcaccctct agcattccat ctgtgccatc
    16501 aatccctaat aaccctatct taccatcagt agatctctcc cttactgcac caaaagaacc
    16561 aaccgaactt gttgccactc tcaatatcgt gcttatcatc acgcttcttg tcattgctcc
    16621 atcgcttgtg cttgtgatga caagctttac acgtattgtc attgtttttg cttttttgcg
    16681 cactgcactt ggcacacagc aatctccccc aacacaagtg cttgttagcc ttgctctaat
    16741 tttgacattt tttattatgg aacctgtggc aaccaaaagc tatgaagtgg gtattaaacc
    16801 ttatgcagaa aaaaaaatct cctatgatga agcctttgaa agagcgattg taccttttaa
    16861 agattttatg attaaaaaca cgcgtgaaaa agatttggct ctttttttta gaatccgcca
    16921 acttgaaaac cctcaaagtg ttaatgatgt gcccttaaca gtgttgcttc cagcatttat
    16981 gattagtgag cttaaaactg cattttggat tggttttttg ctttatctgc cttttttagt
    17041 tattgatatg gttattagct cggtgcttat ggcaatgggt atgatgatgt tgccacctgt
    17101 aatgatttcg ttgcctttta agattcttgt ttttatactt gttgatggtt ggaatctcct
    17161 cataggtaac cttgtgcaag gctttaagta gctaggtcta gaatgaattg tgagcatttt
    17221 ggcatatgtg gaggctgcac aaatatacaa gattattcca cacaactgca ggcaaaacac
    17281 aatcttactt tgcaagaatt tcaatctttt cttgatacaa aaagcaaaaa ttttcaatat
    17341 cccaccaatc ccttagctat agaagtattt gcttcaccgc aagaggggtt tagagctcgt
    17401 gcagagttta gattctctca cgttttccag aataaaagtg ggcttgattt tgctatgaat
    17461 gcatttggtt ataatcaccg tgtgcctatt aaaaaatgtc ctattttgct ccctacttta
    17521 caggacatta tgcctctttt gctgcactat ctcaatacat acgacttact taatcataaa
    17581 ctttatgcgt gcaatctcct ctcctcctta caaaatgaaa ttatcatcac cctcatttat
    17641 cacaaatccc tagattctca ttgggaatct cttgcgttaa aaatacaaaa agagcttgaa
    17701 tatactctta atacgaatat tcacattatc ggacgcagta aaaatcacaa acatatcctc
    17761 tcaaatgata ttatttgtga gcatctcaca ctttttgcca acactccaaa agaacgcact
    17821 tatacatttt tcaaacaaga atcccgattt tgccaaccta atccatttat caacactcaa
    17881 atgcttgaat ttattgtctc cgcactctca tcaatctata ccccacaaac tccttgtgat
    17941 atgcttgaac tctattgtgg tagcggtaac ttcaccattc cacttgcctc aatattccgc
    18001 catatttttg ctacggaagt ggtaaagtct gcaattacac ttttacaaaa aaatatggct
    18061 aaaaataata tagaaaatat tatacctgcg cgacttaacg catttgaaag tatccaagct
    18121 ctgcgtaaag agcgcgtatt ttttcgcctt aaaaatattg atttagatgc ttttgcgttt
    18181 gattgtgtat taattgaccc acctcgtagc ggtgtaggcg aagaagaagt gttgtatttt
    18241 ttgcaaaact ttaacacaat tatatatgtc tcgtgcaatc cccatacgct actaaacgat
    18301 ttgcgcattc tttctcaaag ccattatgta atgcgatttg ggctttttga ccaattccca
    18361 catacatatc atagagagtg catagtaatt ttgcgcaaat ccaataagat tctataaaat
    18421 tattccatct tacgtagcac taaaataaat gcaggaagtg caaaaagcga agcaaaaaga
    18481 ggattaaaac taacacccaa aaatggtgca acaacgacta agccaccaat ttgatttgcc
    18541 aatgcaatgc ctacattaaa ggctgcttca ttgacactta ctgaactatc catagaatct
    18601 ggcgtgtatt tacgtgccat attcattgca ttcactttga gcgctgggat tgaggcaaaa
    18661 gataaaaaac ccataatcgc taaattaatc acaacaaaca cttgtgaatg ggcgctcaca
    18721 ctcacaagag cgtaaaaaat aatttgtaaa aagagcacga tttgtaaagc gcgtcttgag
    18781 cctttattgt ctgcaagcct accgccaaag agattcccta aaattgcaaa tatgccataa
    18841 agtaacaaaa tatatacaat gctcgcctca ttaaaatggc ttttttgtgt gagtaaatct
    18901 gttacataag tataaagtac aaatgcccca ccacaagtgc atatcgtaat tgcataggct
    18961 ttaagtaatg gaatatgtaa aaaagcctta aaaagtgcgt ttatatgcgt tttgcagcct
    19021 tgcaaatggc ttggcataaa agcaattgcg ctaataaaag caataagtgt gcaaaggcaa
    19081 ataagcaaga aaatagattt aaagccaaaa atctgcccaa taaatgtccc caaaggaacg
    19141 ccacttacaa gtgcaatcgt caatccggac accataaggg cgagattgcg agattctttt
    19201 tccttggaag aaacttgaat agccgtaagt gtagcaataa caaaaaacac tccgtgttgt
    19261 gtgcctgcga taaatcgtgc aatcacattg agtataaaat tatcactgat ataaatcaca
    19321 aaatttgcca aagcaaacac accaagatta agcaaaagct gcaatttacg attaaatcca
    19381 cttagaggaa tgcttaaaag tggtgcgcca attactacac ccactgcata catagtcgta
    19441 agcaatcctg cctgattaga atctacacca aaatatgcct ttacatcttg taaaacacct
    19501 gcaataataa attctgtaac tcccatacaa aaagagctaa gagccaaaac taaaatcgtt
    19561 ttgcttgttg cattcaaagc aaatttgttc atcttatgct ttccattttt taattctttg
    19621 ttatttatgt aaaagacctg ccatctctat gatttcaaag ccaaaaatct tttcatcata
    19681 atatcgcatt tcctctataa aatgttcgcc aaaaatggta attgtagttt ttttgcctct
    19741 gctttcaaaa tcaaataatc ccaccatacc aaaggcaact tgattgcttt ttgtgtcata
    19801 tttgaaaaaa gcaaaatgct ctccatttgg ataaaatgta gggaagtaaa aattgtaaat
    19861 ttcattttct ccataggtaa ttgaataagg attataccca taatccccat cgcaataata
    19921 tggaaaacac tctccgctag gctttttagg ataataagca tagcaagaat gttgccaatc
    19981 aagcacaata atctcatttg ctgctttttg ctcctctttt tgagcatagg attttaaatt
    20041 tgtaagagca tatttatcta aaactttcgc aaaaatttgt ggcatactct cttgaaaggc
    20101 tttatgattg actttatcaa aatccgcaat ataaataata tagggcaatt tacgcgcaat
    20161 ctctaaaata ttccaatgtg gcattacatt aaatccaatt ctttcataca taaaatctgt
    20221 ttcctcttcc cctaacactt cataattctc atttggcaca ataagcctct tttttaaaaa
    20281 tatctcgcgt ttgctttgtg ctttctttgc taaatatgct cttaatccca ttctttctcc
    20341 aaaagcctta tctcattatt gctgcaatga ttgcaaaagc gacattatat tataattttc
    20401 aaatagagtt aagataaaga tagaatcctc tttgctgctt attgctttga atatgataaa
    20461 atatgccgaa tttacaaagg atacaaatga aaaatattat ttatggagta tgtctgctct
    20521 gtgcgtgcgt gtttagcgcg tatggagaag ttatcgctgg agtagccata cgcgtaaatg
    20581 gacacgctat cactttatat gaaattgcct ctttgcaatc acatcttaaa atctccaaac
    20641 aagccgctat tgatatgctc attaatgagc ggctcaaaga tgatgaaatt gaacgtttta
    20701 aaatcagcat tgaagatttt aaaattgatg aagaaattgc tctgcttgcc gcaaatgcta
    20761 atctaagcaa agatgaattt cttagaaaag ctacgcatac aatgagtttg caagaatatc
    20821 gcacacaaat taaaaaacaa ctccaaacaa aagaacttat gcagagaatc cttgcttcta
    20881 atattagcat ttcaagtgaa gatgagcttc ttacctatta tacacgacat aaaaaagaat
    20941 ttctaattcc ctcacaagtg cgtgtagtgc gttatttttc tcaaaccgat aatgccttgc
    21001 aaaaggcgat acaatcaccc aaacaaaata ttaaaggtgt gcaaaaagta aatgaaacta
    21061 tcgctctctc ttcccttaat cctcaaattg cccaagtatt tatacacacg ccaaataatg
    21121 aatttactcc tgtgcttacc acaggtggca atggttttgt gagctttttg gtaaaagaac
    21181 gtttaggtga aacccctatt aattttgagg aggcaaaacc tcttatcaat caaaaaatta
    21241 tggcacaaaa agagcagtct attatcgcgg aacactttaa caaaatccgc tctagtgcta
    21301 atattgtaaa tcttagagaa taattatgct ctcttatact gacccacttt ttggcattat
    21361 tatctttgta tctcttatcg ctacggctgc atttattgat tattggcaaa atcgctacaa
    21421 agaaaagaaa aaaaaacgct ctttaaaaaa cttaacaaaa tcgtatgaat ttgctggact
    21481 aacccaagga gtagaagagt tccttgcact ttcgcaaaac cctattccta ctttacaatt
    21541 catcgctaat gcctatattc aaagcggcaa tacgcaagaa gcaattaaaa tttatcttag
    21601 tattttagag aatcttgata attcaaaaga aagtgcaaaa tcaaaaattg agattctcca
    21661 gcagctaggc attgcttact acactgcagg atttttacaa agagcaaaaa atattttttt
    21721 agagattctc aaaaattatc cccgaaatcc tcaagtgctc atttatttgc tcaaaactta
    21781 cgaaaatcta agcgaatata aaaatgctat cgacacactt gaatgtatcg aagaaatcta
    21841 tgattcacac tctaccccta caatagccca agagcaattt tttcatacaa ttgcactcaa
    21901 taaagcttat ttacacacac ttttactcat caatcaatac gctatgcccc tatcaagcaa
    21961 gattcaaagg ctcaatgaaa tcaaagcaaa agaaataaaa cttgaaaaaa ttattctagt
    22021 cttttttaaa agcgtaagtc attcactctt ttgggaagaa atcaataaaa gcgaaaatat
    22081 agcaagcctc attgatgtat tatgggattt tgagcgcaaa aatgtgcctc tagagcaaat
    22141 tacacatccg cagattcttg atatctatcg tgcaaaaggc tggatacaag atacaaaaag
    22201 ttgcaatatt tttgagctag aaaatatgag aatcttaaag caacattcaa ccctttgcat
    22261 agattttagt tttgaatacc gctgccatag ctgcaaacaa gtatttccct ttgaaaacgc
    22321 acgttgttca cattgtggtg agttgcttaa taccgatgta atctataaga tacaaaaggt
    22381 tgataatgaa acaagttact ctttattgtg atggtagtgc acttggaaat cccggtgctg
    22441 gaggctggtg tggcatactc tcttttggtg ataagcaaaa gattcttaca ggtggcgaaa
    22501 cctatacaac aaataatcgt atggaactcc ttgcagtgat agaatctctc aaagctctta
    22561 atcaaccttg cattgtgaat gtatatagtg attctcgcta tgtatgcaat ggtatcaact
    22621 tatggcttaa atcgtggatt tctaagcaat ttaaaaatgt caaaaatcct gatttatggc
    22681 aactatattt acaagtttca tcacctcatc aagtgattgc
//
