LOCUS       c00055_NZ_JPMD..       15831 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JPMD01000055.1 Clostridium sulfidigenes strain 113A c55, whole
            genome shotgun sequence.
ACCESSION   NZ_JPMD01000055
VERSION     NZ_JPMD01000055
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:17:32
            Original ID  :: NZ_JPMD01000055.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15831
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15831
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2681:5831]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2682..5831
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15831
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15831
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             2..157
                     /locus_tag="ctg55_1"
                     /transl_table=11
                     /translation="GSSALGVGVRLPSPAPIIKIKKMREWLSGRASPCQGERREFESRL
                     PLQMRV"
     CDS             complement(784..1875)
                     /locus_tag="ctg55_2"
                     /transl_table=11
                     /translation="MNKNKNFNKIIQILLIINLILLAIGLFSKMNFVLSPITTILNAMF
                     IPIVLAIFLYYLVRPVKRFLQNRKLSSGIATALSILLIIVLIVYMLIYSSSIIATQGES
                     LTIAIIESVQNLADKYSYLFPQINEFLNIGELLQKAANYLVNSFTDISKNIYVFASSIG
                     NFIAQMILIPIIMFYILKDDKKIYNTFTSFLPRKFKSIILKILHEIDTVLKQYITSQIM
                     VACVIGVLMFIGYVIIGMPNALVLSLFSLITAFIPFLGVILGIIPAILISLSMGFGMVL
                     KIIILTVIVQQLEGNVITPNITGNQLNMHPLTTILVVTISVYFGGFFAAFLAVPIYNIV
                     KILVKNLYCYLINKHNTEITVEK"
     CDS             complement(2027..2476)
                     /locus_tag="ctg55_3"
                     /transl_table=11
                     /translation="MRNNAIEFEKYIEEHRLPLNKGLNVDEFTIFSFPEKITINGVTKP
                     VLGGGQDRRAVISLRDDDTLADIFCFNIASISKAQDKYKLYALFNELNSTYKYVSFYED
                     NEIISAKVSLPFNDNFDADLVFQMLSIIFRAVDEEYPKILSTLHN"
     CDS             complement(2682..3425)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 88.2;
                     E-value: 2e-27)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.7e-28, bitscore:
                     90.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTGRIHSIESMGLVDGPGIRTVVFFQGCKLRCAYCHNPDTWNLK
                     DGKEVTSEEIINKIIRFKPYFQPSGGGVTFSGGDPLVQPEFLLELLKKCKELGIHTAID
                     TAGYGHGDYDEILKYTDLVLLDVKHINSDGYVTLTGRDTRDVNLFLSALRKSKARVWVR
                     HVVVPGYTDTLEHMDKIANIIHEEIPNVDKIELLPYHLLGVNKYESLGIDYRLDGVNQM
                     DKETCSQLQDYLISKVQQSKKSKIS"
     CDS             complement(3600..5831)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_5"
                     /sec_met_domain="Gly_radical (E-value: 1.2e-46, bitscore:
                     147.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 5.8e-294, bitscore:
                     966.2, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTQWNGFKGKTWKKEVNIRDFIQTNYTPYEGDASFLTGATEATN
                     KLWNEVSELFKKEIEHGGVLDVDTKTISKIDAYNPGYIDKNLEKIVGVQTDAPLKRAVM
                     PQGGIRMAETAAKSYGYEIDPLISEIFSKHRKTHNQGVFDAYTDEMKLARKYGIVTGLP
                     DAYGRGRIIGDYRRVALYGIDRLIEDKIQQKKSLEVSTIDADVIQLREELSDQIVALNE
                     LKTMAASYGFDISVPAKNAQEAIQWLYFGYLGAIKQQNGAAMSLGRTSTFIDIYIQRDI
                     DNGILTEEDAQEMVDHFVMKLRLVKFLRTSDYNNLFSGDPTWVTEVIGGMGLDGRTLVT
                     KNSFRMLNTLYTLGASPEPNLTVLWSTRLPQGFKDFCSKVSIDTSSVQYENDDLMTTYW
                     GDDYAIACCVSAMKVGKQMQFFGARVNLAKTLLYTINGGVDEKSGVQVAPKMEKITSEY
                     LSYDEVIEKFDVMVEWLAKLYVNTLNVIHYMHDKYSYESLQMALHDRDVFRTMACGIAG
                     LSVCADSLSAIKYAKVKPIRNEQGIAVDFEIQGDFPKYGNDDDRVDDIAVYLVETMMNK
                     VKKNKTYRNAYHTQSVLTITSNVVYGKKTGSTPCGRKAGEPFAPGANPMHGRDSSGSLA
                     SLNSVAKLPYEYSQDGISNTFSIIPDALGKCSENRISNLSNLLDGYFVQNAHHLNVNVF
                     NRETLLDAMDHPEKYPQLTVRVSGYAVNFIKLTREQQLDVVNRTFHASM"
     CDS             6362..7195
                     /locus_tag="ctg55_6"
                     /transl_table=11
                     /translation="MYSEIIKLTMEVKAVRKKPSMFSKDYRRQLKLRRIKYMIIFLIII
                     MVIGITGLVFTNREGIVAIKNFFIKESTEDNNHKSEENKNKTEENSEEESVVEEKSTKT
                     YSDVVLKSGKKVTINYEEKDQVKKINTIDSDSQVKCSIAPSQEMILILDKEAQDMYILN
                     SNEKLINITNEQYVSTTNEVFNKENVLKYNPSYKWVESAQFIDNTHIAYSSSLPWINNS
                     DDKYLWIYNMESNTHRGFYNVKGKTFEVGQITDKGLTISLDNKEIVVDKDGKIVE"
     CDS             7397..8686
                     /locus_tag="ctg55_7"
                     /transl_table=11
                     /translation="MNVKMEKLEKNVVKFEVTIGADKFAEAVKKSYAKNAKKFNVPGFR
                     KGKAPMNIIKQYYGEGALYEDAINYIYETTYPEVLAENNINPVDYPSIDIVQIGEGKEF
                     IYTASVPVVPEVELGAYKGIEAKKEVVEVTDEDVENKLKELQAQNTRVEVKEGAVEKGD
                     IAVIDFKGYVDEVAFEGGEAKDYELEIGSGSFIDNFEDQLVGLTAGESKDVNVNFPEQY
                     GKEDLNGKPAKFEVTVKSVKKKELPEITDEFASEVSEFETLEELRNNIKEELVKANELK
                     AINDYEMAVIEAVVANANVEIPDAMVNRELDGMLQDLENRLKYQGLDIESYFKFTNTSE
                     ADFREQMKDIATKNVKNELVLSEIAKAEKIEASEDEIREKATEIASKYGEAEKLEETVD
                     RLVQVQREYLGTQIVNEKIKNMIMENSKTI"
     CDS             8809..9393
                     /locus_tag="ctg55_8"
                     /transl_table=11
                     /translation="MSYIPMVVEQTGKGERSYDIYSRLLKERIIFLSDEVNDVTASLIV
                     AQLLFLESEDPDKDIYLYINSPGGSITSGMAIYDTMNYIKPEVSTICVGMAASMGAFLL
                     AAGQKGKRYALPNSEIMIHQPLGGFKGQATDIDIHAKRILKIKETLNEILSERTGKPLD
                     KIKQDVERDYFMSADEAKEYGLVDEVIVKKK"
     CDS             9412..10704
                     /locus_tag="ctg55_9"
                     /transl_table=11
                     /translation="MPRNEEKKKFKCSFCGKSEEQVRRLIAGPGVYICDECIELCSEII
                     VDEREEDVQIDMGTLPKPKEIRKYLDQYVVGQDDAKKALSVAVYNHYKRINSNVMDNDI
                     ELQKSNILLLGPTGSGKTLLAQTLAKMLNVPFAIADATTLTEAGYVGEDVENILLKLIQ
                     NSDYDIERAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVSSVPPQG
                     GRKHPHQEFIQINTSNILFICGGAFDGLEKIITKRTQKSAMGFGAEVVSKEKQDLGELF
                     KQIMPGDLLKFGLIPEFVGRIPVIVTLDNLDEDALVKILSEPKNALVKQYQKLLEIDDV
                     RLEFDENALIAIAKEAIKRSTGARGLRAIIEDIMQEIMYEIPSREEIEKVIIHEETLNT
                     KIPEYIIADSGKREPLKIDSKKGVKRTPELA"
     CDS             10844..12535
                     /locus_tag="ctg55_10"
                     /transl_table=11
                     /translation="MEPVAILIMLIQLLVTIVMGIYFFNALKGQKSSKITINKENTKEI
                     EKLRKLKSICLTEPLTEKSRPRNFEDIIGQEKGIKALKAAICGPNPQHVIIYGPPGIGK
                     TAAARLVLEEAKLIPASPFKATSSFVEIDATTIRFDERGIADPLIGSVHDPIYQGAGPL
                     GVIGVPQPKPGAVTKAHGGVLFIDEIGELHPIEMNKLLKVLEDRKVFLDSAYYNSEDPN
                     MPSYIKEIFEEGLPADFRLIGATTRSPEEIVPAIRSRCVEIFFRALDGDEIEIIAKNAA
                     EKIGISIEEEAAKLVGMFANNGRDAVNLVQLACGIVINENRNTVSINEIQWVIENGQYS
                     PKPNKKICAKPKVGYVNGLAVYGSNVGSVMEIEATATKAREREGIVKITGIVEEEELGD
                     KGRKLKRKSTARNSIDNVITVLERIYNIDTKKYDIHVNFPGGIPVDGPSAGISMTTAIY
                     SAITGRSVDNNTAMTGEISIHGEVKPVGGVTAKITGAIKAGATKVLIPKENWQEVYKDY
                     KDIKVIPVNTIKEVIDEAIIKEQILHISVEKKDQGFEVNMLPQLDA"
     CDS             12852..15185
                     /locus_tag="ctg55_11"
                     /transl_table=11
                     /translation="MENQIMKLPLIPLRGLSIFPHMALNFDIGRKKSIEAINRAMDEDQ
                     KIFIISQRESTTENPTEKDIYNVGCVCTIKQFMKLPGNHLRVLVEGEYRAKLVKYLDED
                     DCISAEVEAVEELDIEDKTESEGYKNSLNDMFINYLELAGEEFKDLIVELEEEEDNSVY
                     CDVISAFLPVKADVKQELLEITSIKERMEKLLVILKKEIEVVKVEKLISNKVKARVSAS
                     QKEYYLREQLKVIQEELGEEDEFGREIANYEKKLGQIKLPKDVKTKIEFEINRLKNIGP
                     SSQEGSVIKTYLDTILGMPWNKLTKDNLDLTNARKVLDEEHYGLEDVKERIIEYLAVRK
                     MSKSLKSPIVCLVGPPGVGKTSIAKSVANSLGRKFVRMSLGGVKDEAEIRGHRKTYVGA
                     IPGRIVSALKEVGYKNPVCLLDEIDKVSKDYKGNVEDALLEVLDSEQNKTFRDHYIDVE
                     FDLSKVLFITTANTLDTISRPLLDRMEVIEVSGYTTEEKYEIAKKYLVPKVMKEYSVED
                     GQIIVNESALRTIIDRYTRESGVRNLERKIASVIRKSITEIIESNKKKITINSLTVKKY
                     LGSELYSYDDLDKEDKIGVVTGLAWTGYGGDTLPVEVAVMDGDGKLQLTGQLGDVMKES
                     AKAGYSYVRAHCDMYGIDKEFYKNKDIHIHIPEGAIPKDGPSAGVTMVTAMVSALSNRK
                     IKYSVAMTGEVTLTGRVLPIGGLKEKSLAAYRMGIKTIIIPKANEKDLKDIPKVIKNRI
                     KFIPVEKIEDVLKNALVGEEKNGN"
     CDS             15175..15765
                     /locus_tag="ctg55_12"
                     /transl_table=11
                     /translation="MEIKQAEFKTSAVKPTQYPEDGMCEIAFVGRSNVGKSSLINTLTN
                     RRKLVKVSGTPGKTRLINFFTINNKLYFVDLPGYGYAKVSKSEKATWGKMMEQYLINRP
                     ELKKVVILVDCRHKPTGDDIMMYEWIKHYGYEVIVVATKKDKLTKSELQRSAKVIKETL
                     KLGKEDKLLFFSSLKKEGKEELLEEIFKDLGIE"
ORIGIN
        1 aggatctagc gccttaggcg tgggggttcg actcccttca cctgcaccaa tcataaaaat
       61 aaaaaaaatg cgggagtggc tcagtggtag agcgtcacct tgccaaggtg aacgtcgcga
      121 gttcgaatct cgtcttccgc tccaaatgcg ggtgtaactc aatggtagag tgctagcctt
      181 ccaagctagt tacgagggtt cgattccctt cacccgctcc aaaatatgcg tctttagctc
      241 agctggatag agcaacgccc ttctaaggcg tgggccaggg gttcgaatcc cttaagacgc
      301 accatatatc ggggtgtggc gcagatggga gcgcgcgtgg tttgggacca tgaggtcgca
      361 ggttcaatcc ctgtcacccc gaccacttta aattaaatat gtgcgggtgt aactcaatgg
      421 tagagtgcta gccttccaag ctagttacga gggttcgatt cccttcaccc gctccatttt
      481 tttatttttt gagaaggtat tttataagga attcatattt tatttttgca cccatagctc
      541 agctggatag agcgctggac ttcgaatcca tcggtggcag gttcaaatcc tgttgggtgt
      601 accatgaatg tagtgatatc gacgatttca gtagatgaaa tcgttggtat ttttttatta
      661 ttaatttatg attaatgatg aaatttactc aggaacaaca atattagaga aaatgataga
      721 gtaaaaagta aaaaaataag cactgatgag ttaaatcaat agtgcttatt ttaatattgg
      781 aagttatttt tcaactgtaa tttccgtatt atgcttattt atcaaataac aatataaatt
      841 cttaacaaga attttaacaa tgttatatat aggaactgca aggaatgctg cgaagaaacc
      901 tccaaagtat acacttatgg taactactaa aatagttgtc agtggatgca tattcagttg
      961 gttaccagtg atattagggg ttataacatt gccttctaac tgctgaacaa taactgtaag
     1021 aattattatt ttaagtacca taccaaagcc catacttaag gatataagga tggctggaat
     1081 aattcccagt attacgccta aaaaaggaat aaaggcagtt ataagagaaa atagagatag
     1141 aacaagagca ttaggcattc caatgattac ataacctata aacataagaa ctccgatgac
     1201 acaagcaacc ataatctgtg aagtaatata ttgttttaat actgtatcaa tttcatgaag
     1261 tattttcaat ataatacttt taaattttct tggaagaaag gaagtgaaag tattatatat
     1321 ttttttgtca tctttaagta tataaaacat tattattggt attaaaatca tctgagctat
     1381 aaaattacct atagaactag caaatacata tatgttttta cttatgtctg taaaagaatt
     1441 tactaaatag ttagcggctt tttgaagtaa ttcaccaata tttaaaaatt cattgatttg
     1501 tggaaataag tagctatatt tatctgctaa gttctgtacg gattcaataa tagctatggt
     1561 taaactttca ccttgagtag ctattatcga tgaagaatat ataagcatat atacaattaa
     1621 tactattatc aatagtattg aaagggctgt agctattcca cttgataatt tcctgttttg
     1681 aagaaatctt ttcacaggtc tcactaaata gtaaagaaaa attgctaaaa ctataggtat
     1741 aaacatagca ttaagaattg tagttatagg agatagtaca aaattcattt tactgaagag
     1801 tcctatagct aatagaatta aatttattat taaaagaatt tgtattattt tattaaaatt
     1861 tttattttta ttcatttttt cctcctctaa tttaaatttt agaacaatga agactttgag
     1921 atctatttaa ctataattaa gctaatgcca ttatatgcca tagcataaat gattaaaaaa
     1981 atacatgcta gaaaattaaa actagcatgt tagttttcta gattatttag ttgtgcaagg
     2041 tagaaagaat tttagggtat tcctcatcta cagctctaaa tataatagaa agcatttgga
     2101 aaactaaatc tgcatcaaag ttatcattaa atggtaggga tacttttgca cttataattt
     2161 cattatcctc ataaaaggat acatatttat atgtagagtt taattcattg aataaagcat
     2221 ataacttata tttatcttga gctttagata tagaggctat attaaagcag aagatgtcag
     2281 ctaatgtatc atcatctctt aatgatataa cagctcttct atcttggcca cctcccagaa
     2341 ctggtttagt aactccgttt atagtgatct tttcaggaaa tgaaaagatg gtaaattcat
     2401 ctacattgag tcctttgttt aatggaagtc tatgttcttc tatatatttt tcaaattcta
     2461 tagcattatt tctcatacta tttccccctt gaataaaatt tatataaata tattttttga
     2521 atattatata tattataatg tattagtaat tatctcataa aagagatggt tagtaaatag
     2581 aattgtataa cttataagta tatgatttaa attataattt attactaacc tgtggataaa
     2641 cttggggatt atgtggaaaa aaatgtaaaa gtattaacgg attaagaaat tttactcttt
     2701 ttactctgtt gaactttaga tattaaataa tcttgaagtt gactacaagt ttctttgtcc
     2761 atttgattta caccatctag cctatagtct atacctaaac tctcatactt atttacacct
     2821 aaaagatgat aaggtaataa ttctatttta tctacattag gaatttcttc atgtattata
     2881 ttagctatct tatccatatg ctctaaagta tctgtataac caggaactac cacatgccta
     2941 acccatacac gggctttaga ttttctaaga gctgacaaga ataagttaac atctcgtgta
     3001 tccctaccag taagagttac atatccatca ctattaatat gttttacatc taataaaact
     3061 agatcagtat actttaatat ttcatcatag tcaccgtgtc catagccagc ggtatcaata
     3121 gctgtatgaa tacctagctc tttgcatttt tttaataatt ctaataaaaa ttcaggttga
     3181 acaagagggt ctccaccaga gaatgttaca ccacctccag aaggttgaaa atagggttta
     3241 aatcttatga ttttatttat aatttcttca gaagtgactt ccttaccatc ttttaagttc
     3301 caagtatctg gattgtggca ataagcacac cttaatttgc atccttgaaa aaatactaca
     3361 gttcttatac caggaccatc gactaagccc atgctttcta ttgagtgaat tctaccagtt
     3421 ttcattataa agcctccttg caatttaaac taaataacat aattaacttt atacaaaaaa
     3481 taaattgaat aatttctcta taaaattaat ttaagttcct ttcaaaatac taaatatagt
     3541 agagatatct aactaagaca tctctactat gttattataa ttaattcttt ttatttagat
     3601 tacattgatg cgtggaaagt tctgttaaca acatctaatt gttgttctct tgttagttta
     3661 ataaagttaa cagcatatcc agaaactctt acagtcaact gaggatattt ttctggatga
     3721 tccatagcat ctaataaagt ttctctatta aatacattta catttaagtg atgagcattt
     3781 tgcacaaaat atccatctaa taagttactt aagtttgata ttctgttttc agagcacttt
     3841 cctaaagcat ctggaataat tgagaaagta ttagaaatac catcttgaga atattcatat
     3901 ggtaatttag ctacagagtt tagagatgct aaagaaccgc tactatctct tccgtgcata
     3961 ggattagcac caggagcaaa tggctcaccg gcttttcgtc cgcaaggtgt tgaaccagtt
     4021 tttttaccat aaactacatt tgaggttata gtaagcactg attgagtgtg atatgcattt
     4081 ctgtatgttt tgttcttttt aaccttattc atcatagttt caactaagta tactgctata
     4141 tcatcaactc tatcatcatc atttccatat ttagggaagt caccttggat ttcgaagtct
     4201 actgctattc cttgttcatt tctaataggc ttaactttag cgtatttaat tgcagataaa
     4261 gagtctgcac atactgaaag tccagctata ccacatgcca ttgttctaaa tacatctcta
     4321 tcatgtaaag ccatttgtaa agattcataa gagtatttat catgcatata gtgaataaca
     4381 ttcaatgtgt taacataaag tttagctaac cattctacca taacatcgaa tttttctata
     4441 acttcatcat agcttaagta ttcagaagtg attttttcca tcttaggagc aacttgtact
     4501 ccagattttt catctacacc accatttata gtgtataata aagtcttagc taagtttact
     4561 ctagctccaa agaattgcat ttgtttacca actttcatag ctgatacaca acaagctata
     4621 gcgtagtcat caccccaata agttgtcatt aaatcgtcat tctcatactg aacagagctt
     4681 gtatcaatag atacttttga acagaaatct ttaaatcctt gaggtaatct tgttgaccat
     4741 agtacagtta agtttggctc aggtgatgct cctaatgtat ataatgtatt aagcattctg
     4801 aaagagtttt tagttactaa tgttcttcca tctaatccca taccacctat tacttcagta
     4861 acccaagttg gatctccgga gaataggttg ttataatcag aagttcttaa aaactttact
     4921 aatcttaact tcattacaaa gtgatctacc atttcttgag catcttcttc agtaagaatg
     4981 ccattatcga tatctctttg aatatatata tcaatgaaag tagaagttct accaagagac
     5041 atagcagcac cattttgttg ttttattgca ccaagatacc caaaatataa ccattgaata
     5101 gcttcttgag catttttagc aggaactgat atatcaaatc cataactagc tgccattgtt
     5161 tttaactcgt taagagccac tatctgatca gataattctt ctcttaattg aataacatca
     5221 gcatctatag tgctaacttc taagcttttc ttttgttgaa ttttatcttc tattaatcta
     5281 tctataccat ataaagcaac tcttctatag tcacctatga ttctacctct tccataagca
     5341 tctggtaaac ctgttactat accatacttt ctagctaatt tcatttcatc tgtatatgca
     5401 tcaaaaactc cttgattatg agttttacga tgttttgaga atatttcaga aatcaaaggg
     5461 tcaatttcgt atccataaga tttagctgcg gtttcagcca ttcttattcc accttgaggc
     5521 ataacggctc ttttaagtgg agcgtcagtt tgaacaccaa caattttttc aagattctta
     5581 tctatatacc ctgggttata tgcatctatc ttagatatgg ttttagtatc aacatctaaa
     5641 actccaccgt gttctatttc ttttttaaat aattcgctta cttcattcca caatttgttt
     5701 gtagcttctg tagcacctgt taaaaatgat gcatcacctt catatggagt atagttagtt
     5761 tgaatgaagt ctcttatatt aacttccttt ttccaagttt tgcctttaaa gccattccat
     5821 tgagtaaaca tatataatcc tcctaaaaaa taatttttaa taaaattaaa gtataaaaca
     5881 gatgtagttt atttgtttta tgtactaaaa ttattaatca ataatttgaa tttaaattta
     5941 attttatctc catctgttat aattgtacaa ctataacaga tgaaaaacaa cagttttttt
     6001 aacagggata aaagattaaa aattgagaaa attcaaacaa gtaaaggatt aaatttgcga
     6061 aattcagtaa aaaagataat tgcaaggaga catttaacaa ttttcattaa aggttaattt
     6121 gaagatgaat ataacagttt aaatgaaatt ttgaaacaga gagaagttaa tttgttgtaa
     6181 aatacaattt catatattaa agtaatacag caatgataaa tgaaaaaata aaataaaaaa
     6241 taaagctggt taatataatt aaataaatta attgtaaatt taaattgatt tggtataaaa
     6301 aaatgttaat ttataataag ttgagttata ataagttatg agaatataat tattaatcaa
     6361 aatgtatagt gaaataataa agttaactat ggaggtaaaa gctgtgagga aaaagccaag
     6421 tatgtttagt aaggattatc gcagacagtt aaagctgagg cgtataaaat atatgattat
     6481 atttttgatt ataataatgg ttattgggat aactggatta gtttttacta atagagaagg
     6541 aatagtggct ataaaaaatt tttttattaa agaaagtaca gaggacaata accataaatc
     6601 agaagaaaat aagaataaaa ctgaagaaaa ttctgaagag gaaagtgttg tagaggaaaa
     6661 gtctactaaa acctattcag atgtagttct taaatcagga aaaaaagtta ctattaatta
     6721 tgaagaaaaa gatcaagtta agaaaatcaa cacaattgat tcagattcac aagttaaatg
     6781 tagtatagcc ccatcacaag aaatgatttt aattttagac aaagaagctc aagatatgta
     6841 tattttaaat agtaacgaga aactaataaa cattaccaac gaacagtatg tatcaactac
     6901 taatgaagta tttaacaagg aaaacgtatt aaaatataat ccttcttata aatgggttga
     6961 aagtgcacaa tttattgaca atacacatat tgcatattct agtagcttgc cttggataaa
     7021 taacagtgat gataagtatt tgtggatata taacatggag agtaataccc ataggggatt
     7081 ttataatgta aaaggaaaaa cttttgaagt gggacaaata acagataagg gtcttactat
     7141 atctttagac aataaggaaa tagttgtgga taaagatggt aaaatagttg aataaatata
     7201 tcatgggaaa aagtattgta cataataata gtattattgt ataatttatt aggtaatatt
     7261 taatttatta tcataaattt agagaatgat gatggatctg actaacagtt aaatgatgaa
     7321 atgtactatt tactttacta aatttatgtt ataattttaa gaaatacaga gttgggaata
     7381 ttaggaggaa gaaataatga acgttaaaat ggagaagcta gaaaaaaacg ttgttaaatt
     7441 tgaagtaaca ataggagcag ataaatttgc agaggctgtt aaaaaatctt atgcaaaaaa
     7501 tgcgaaaaaa ttcaatgtgc ctggatttag aaaaggtaag gctccaatga atataattaa
     7561 acaatactat ggtgaaggtg cattatatga agatgctata aactacatat atgaaactac
     7621 ttatccagaa gtattagcag aaaacaatat aaatccagta gattatccat caattgatat
     7681 tgttcaaatt ggtgaaggta aggaatttat atatactgcg tcagtaccag tagtaccaga
     7741 agttgaatta ggtgcttata aaggaataga agcaaagaaa gaagtagtag aagttacaga
     7801 tgaggatgta gaaaataaat taaaagaatt acaagctcaa aatacaagag tagaagttaa
     7861 agagggagct gttgaaaaag gtgatatagc tgttatagac ttcaaagggt atgtagatga
     7921 agttgctttt gaaggcggag aagctaaaga ttacgaatta gaaataggtt caggtagctt
     7981 tattgataac tttgaagacc aattagttgg attaacagct ggagagtcta aagacgtaaa
     8041 cgttaatttc ccagaacaat atggaaaaga agatttaaat ggaaaaccag ctaaatttga
     8101 ggtaacagtt aaatcagtta agaaaaaaga attaccagaa ataactgatg aatttgctag
     8161 tgaggtttct gaatttgaaa ctttagaaga acttagaaac aatataaaag aagaattagt
     8221 aaaagctaac gagttgaaag caattaatga ctatgaaatg gctgttatag aagctgtagt
     8281 agctaatgct aatgtggaaa ttccagatgc tatggtaaat agagaattag atggaatgct
     8341 acaagattta gaaaatagat taaagtatca aggtttagat atagaaagtt acttcaagtt
     8401 tacaaatact tcagaagctg actttagaga acaaatgaaa gatatagcaa ctaaaaatgt
     8461 taaaaacgaa ttagtattaa gtgaaattgc taaagctgag aaaattgaag catcagaaga
     8521 cgagataaga gaaaaagcta cagagattgc tagcaagtat ggtgaagctg agaaattgga
     8581 agaaactgtt gatagattag ttcaagttca aagagaatac cttggaactc aaatagtaaa
     8641 tgaaaaaatt aagaacatga taatggaaaa tagcaaaact atttaagtta attaataatt
     8701 gccagtatat actggcaatt attttaaata aaataggtta aaataatttt aatgaggata
     8761 taatagtaaa tattctaata tatttacaat agtaaggagg ttgtaattat gagttatata
     8821 ccaatggttg tagagcaaac tggtaagggc gagcgatctt atgatatata ttctagatta
     8881 ttaaaagaaa gaattatttt tttatcagat gaagtaaatg atgttactgc tagtttaatt
     8941 gtagcgcaac ttttattttt agagtcagag gatccagata aggatatata tctatatata
     9001 aatagccctg gtggttcaat aacttctgga atggcaattt atgatactat gaactatata
     9061 aagccggagg tttctacaat ttgtgtagga atggctgcat ctatgggagc ttttttactt
     9121 gcagcaggac aaaaaggaaa aagatatgcg cttcctaaca gtgagataat gatacatcag
     9181 ccgttaggtg gatttaaagg tcaagcaact gacattgata ttcatgctaa aagaatatta
     9241 aagataaaag aaactcttaa tgaaatatta agtgaaagaa caggcaagcc tttagataaa
     9301 ataaaacaag atgttgaaag agattatttt atgtctgcgg atgaagctaa ggaatatgga
     9361 ttagtagatg aagtaattgt taaaaagaaa tagctttaaa ggggtgtcaa catgccaaga
     9421 aatgaagaaa agaaaaaatt taaatgttct ttttgtggaa aaagtgaaga acaagtaaga
     9481 agacttattg caggtccagg tgtatatatt tgtgatgagt gcatcgagct gtgttctgaa
     9541 atcatagtag acgaaagaga agaggatgtc caaattgaca tgggcacatt acctaaacct
     9601 aaagaaatta gaaagtattt agatcagtat gtagtagggc aagatgatgc taaaaaggct
     9661 ttgtctgtag cagtgtataa tcattataaa agaataaatt ctaatgttat ggataatgat
     9721 atagaactac aaaaaagtaa tatacttctt ttaggaccaa caggttcagg taaaacttta
     9781 ttagctcaaa cactagcaaa aatgttaaat gtaccttttg caatagcaga tgctacaacc
     9841 cttacggaag ctggatatgt aggtgaggac gtagaaaata tattattaaa attaattcaa
     9901 aactctgatt atgatataga aagagctgaa agaggcatta tctatatcga tgagattgat
     9961 aagattgcac gtaagtctga aaatccatct ataactagag atgtttctgg tgaaggtgtt
    10021 cagcaagctt tacttaaaat tcttgaggga actgtatctt ctgtaccacc acagggagga
    10081 agaaaacatc cacatcaaga gtttatccaa ataaatacat ctaatatatt atttatttgt
    10141 ggtggagctt ttgatggatt agaaaaaatt ataacaaaga gaactcaaaa atcagccatg
    10201 ggatttggtg cagaggtggt atctaaggaa aaacaagact taggagaatt atttaagcaa
    10261 ataatgccag gtgatttact gaagtttgga ttaattccag agtttgtagg aagaattcct
    10321 gtaatagtaa ctttagataa cttagatgaa gatgctcttg taaaaatatt aagtgaacct
    10381 aaaaatgcat tagtaaagca gtatcaaaag ttattagaaa ttgatgatgt tagacttgaa
    10441 tttgatgaaa atgctcttat agctatagct aaagaagcaa taaagagaag cacaggagca
    10501 aggggattaa gagcaataat agaagatata atgcaggaga taatgtatga gattccttca
    10561 cgtgaagaaa tagaaaaggt tataattcat gaagaaactt taaatacaaa gattcctgaa
    10621 tatatcattg cagacagtgg aaaaagagaa cctttaaaaa tagatagtaa aaagggcgta
    10681 aagagaacac ctgaacttgc ataatataaa aactgctgaa tttcagcagt tttttcttgt
    10741 tatagaatat taatccaata tattgtgaat aatactattg tgacttaaat aattagtaaa
    10801 gggagggaag attagtttgc ttataaagta ggctaatatt gatatggaac cagtagcgat
    10861 tttaattatg ctaatacaac tattagttac aatagtaatg ggaatttact tctttaatgc
    10921 attaaaggga caaaaatcat ctaagattac aattaataaa gagaacacta aagaaattga
    10981 aaagctgaga aagttaaaaa gtatatgttt gaccgagcct ttaacagaaa agagtagacc
    11041 tcgaaatttt gaagatataa ttggtcaaga aaaggggatt aaggctttaa aagcagccat
    11101 atgtggtccc aatcctcaac atgttataat atatggacct ccaggaatag gaaaaacagc
    11161 agcagcaaga ctggtattag aagaggcaaa actaattcca gcttcaccat ttaaggcaac
    11221 ttcttctttt gtagaaattg atgctacaac tataagattt gatgaaagag gaatagcgga
    11281 tccattaata ggatcagttc atgatccaat atatcagggg gcgggtccat taggtgttat
    11341 aggggtacca caaccaaaac ctggagcagt tacaaaagca catggaggag tcctatttat
    11401 tgatgaaata ggtgaattac atcctataga aatgaataag ttattgaaag ttttagaaga
    11461 tagaaaagta tttttggata gtgcatatta taatagtgaa gatcctaata tgccatctta
    11521 tattaaagag atatttgaag aaggacttcc tgctgacttt agattaatag gtgcaacaac
    11581 tagaagtcca gaagaaatag ttccagctat caggtctaga tgtgtagaaa tattttttag
    11641 agctctagat ggtgatgaaa ttgagataat tgcaaaaaat gcagcggaaa aaattggaat
    11701 atcgatagaa gaagaagcag caaaactagt tggaatgttt gctaataatg gtcgtgatgc
    11761 tgtaaatttg gttcaattag cttgtggaat tgtaattaat gaaaatagaa atactgttag
    11821 tataaatgaa atacaatggg ttattgagaa cggtcaatac tcaccaaagc ctaataaaaa
    11881 aatatgtgcg aagccaaagg ttggttatgt aaatggtctt gcggtatatg gttcaaatgt
    11941 tggatctgta atggaaatag aggcaacagc aactaaggca agagaaagag aaggaatagt
    12001 aaaaataaca ggtattgttg aggaagagga attaggagat aagggcagaa aattaaaacg
    12061 aaaaagtaca gcaagaaatt ctattgataa tgtaattaca gtgttggaga gaatatacaa
    12121 catagataca aaaaaatacg atatacatgt taattttcca gggggaattc ctgtagatgg
    12181 tccttcggct ggaataagta tgactactgc aatctatagt gcaataacag gtaggagtgt
    12241 agataataat acagctatga caggagaaat atctattcat ggtgaagtaa agccagttgg
    12301 tggtgttaca gctaagatta ctggtgctat aaaagctggt gcaacaaagg ttttaattcc
    12361 aaaagaaaat tggcaagagg tatataaaga ttataaagat ataaaagtaa taccggtaaa
    12421 tactataaag gaagtaatag atgaagcaat aataaaagaa caaattcttc acataagtgt
    12481 agagaaaaaa gatcaagggt ttgaagtgaa tatgttacct caattagatg cctaaatcta
    12541 atccctatag aagttcaatg gataaaactt ttatagggat tatttaattg aaaaattata
    12601 tttttatagg tataatatac tagtctaatt ataattaata caacaacgac atatcattta
    12661 gatgtttatt aaagtaggat tttcttttat aagttgtatt ttacaataaa aaagaaaaca
    12721 ctgcactgcc ctgaaagatt cctgtataaa tactttaggt tgaattatta gtttgagcaa
    12781 actaggtaag attttataat atgaaattaa gtaagattaa ataatagatt agatagaaat
    12841 gaggagatgt tatggaaaat caaataatga aacttccatt aattcccctt aggggattaa
    12901 gtatctttcc acatatggct ttaaactttg atataggaag aaagaaatct atagaagcaa
    12961 ttaatagagc catggatgaa gatcagaaga tatttataat aagtcaaaga gaatcaacta
    13021 ctgaaaatcc aactgaaaaa gatatatata atgttggatg tgtatgtaca ataaagcaat
    13081 ttatgaagtt gccagggaat cacttgcgag tattagtaga gggagaatat agggctaaac
    13141 ttgtaaaata tttagatgaa gatgattgta taagtgcaga agttgaagct gttgaagagt
    13201 tagatataga agataaaaca gaatctgaag gatataaaaa ctcactaaat gatatgttta
    13261 ttaattactt agaattagct ggtgaagaat ttaaagattt aatagtggaa ttagaagaag
    13321 aagaagataa tagtgtatac tgcgatgtaa taagtgcatt tctaccggta aaggctgatg
    13381 taaagcagga gttattagaa attacttcaa taaaagaaag aatggaaaaa ttattagtta
    13441 ttcttaaaaa agagattgaa gttgtaaaag tagagaagct tataagtaat aaggttaaag
    13501 ctagagtaag tgcatctcaa aaggagtact atcttagaga acaacttaag gtaattcaag
    13561 aagaactagg agaagaggat gagtttggaa gagaaatagc taattatgaa aaaaaattag
    13621 ggcaaattaa attacctaaa gatgttaaaa ctaagataga atttgaaatt aatagactta
    13681 aaaatattgg gccttcatct caagagggat cggttataaa aacttattta gatactattt
    13741 taggtatgcc atggaataag ctaacaaaag ataatttaga cttaactaat gctagaaaag
    13801 ttttagatga ggaacattac ggactagaag acgtaaaaga aagaattata gaatatttag
    13861 cagttagaaa aatgagtaaa tcattaaagt cacctatagt atgcttagtt ggaccgccag
    13921 gggttggtaa aacatctatt gcaaaatcag tggctaattc actaggacga aaatttgtaa
    13981 gaatgagttt aggtggagta aaagatgagg ctgaaattcg aggccacaga aaaacttatg
    14041 taggagcaat tccaggacga attgtatctg cattaaagga agttggttac aaaaatccag
    14101 tatgcctatt agatgaaata gataaagtat caaaggatta taaaggaaat gtagaagatg
    14161 ctcttcttga ggtgctagat tcagaacaga ataagacctt tagggatcat tatatagatg
    14221 tagagtttga tttgtcaaag gtattattta taactacagc aaatacttta gatactatat
    14281 ctagaccact attagataga atggaagtaa tagaggtttc aggctatact acagaagaaa
    14341 aatatgaaat agcaaagaaa tatttagtac ctaaagttat gaaggaatat tctgtggaag
    14401 atggtcagat tatagttaat gaaagtgctt taagaactat aatagataga tatacaagag
    14461 aatcaggagt taggaatcta gaaagaaaga tagcttcagt aataagaaaa tctataaccg
    14521 aaataataga aagtaataag aaaaaaataa ctataaattc tttaactgtt aagaagtatc
    14581 taggttctga attgtatagc tatgatgatt tagataaaga ggataagatt ggagtagtca
    14641 caggtcttgc atggactgga tatggtggtg atacgcttcc cgtagaagta gcagtaatgg
    14701 atggtgatgg taaacttcaa cttacaggcc aactaggaga tgtaatgaag gaatcagcta
    14761 aggcgggtta cagttatgta agggctcatt gtgacatgta tggtatagat aaagaatttt
    14821 ataaaaataa agatatacac attcatatac cagaaggagc tattccaaag gatggtccat
    14881 cagctggagt tactatggtt acagctatgg tttctgcttt aagtaacaga aaaataaaat
    14941 attcagtagc tatgacagga gaagttactt taactggtag agtattacct atagggggac
    15001 ttaaagaaaa aagtctggct gcttacagaa tgggaataaa aactataatt attcctaaag
    15061 ctaatgaaaa agacttaaag gatataccaa aagttataaa aaatagaata aaatttatac
    15121 cagtagaaaa aattgaagat gtattgaaga atgcactagt tggagaagag aaaaatggaa
    15181 attaaacaag cagaatttaa aacttcggct gtaaagccca cccaatatcc agaagatgga
    15241 atgtgtgaaa ttgcctttgt tggtagatct aatgtaggaa agtcgtcact tattaatact
    15301 ttaacaaata gaagaaagtt agttaaggta agtggtacac ctggcaaaac aagacttata
    15361 aatttcttta ctataaataa taagctatac tttgtagatt tacctggata tggatatgct
    15421 aaagtgtcaa aaagcgagaa ggctacttgg ggaaaaatga tggaacaata tttaataaat
    15481 aggccagaat tgaaaaaagt agttatttta gtggactgta ggcataaacc aactggtgat
    15541 gatataatga tgtatgagtg gattaagcat tatggttatg aagttatagt tgtagcaact
    15601 aaaaaagata agttaactaa aagtgaatta cagaggagtg ctaaggtaat aaaagaaacc
    15661 ttaaagcttg gaaaagaaga taaattattg ttcttctctt ctttaaaaaa ggaaggaaaa
    15721 gaagaattac ttgaggaaat atttaaagac ttaggaatcg aataaaataa agggttattg
    15781 attagagaaa tcaataaccc tttatttatg atataataat attgatttac t
//
