LOCUS       c00025_NZ_JAQC..       17073 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAQCOQ010000025.1 Phocaeicola coprocola strain AF02-37
            AF02-37.Scaf25, whole genome shotgun sequence.
ACCESSION   c00025_NZ_JAQC..
VERSION     c00025_NZ_JAQC..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:33:33
            Original ID  :: NZ_JAQCOQ010000025.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17073
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17073
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3524:7073](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3525..7073
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..17073
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17073
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             85..288
                     /locus_tag="ctg25_1"
                     /transl_table=11
                     /translation="MKALNVVAAFLGGLALGAAAGVLFAPEKGEDTRSKIAELLRKKGI
                     RLNREEMDDLVDQIASEVKDAE"
     CDS             370..741
                     /locus_tag="ctg25_2"
                     /transl_table=11
                     /translation="MFANDKSIDNLTELFKEVKKYLKLQGEYVKLDLVEKLTILLSTLT
                     LIFVLIILGTMAAFYLSFMLVYVLASATGSLVAGYAIIGGILILLAFIIYRLRQKLIFQ
                     PMVNFLARLFLDDSSNNSL"
     CDS             752..1015
                     /locus_tag="ctg25_3"
                     /transl_table=11
                     /translation="MKTEQPITYSIESIRERRLAKQEELKLSKDRMHNLSQQLFAPQQG
                     QNKIDSLMQQINMGIAAYDGLMTGIKILRRVRGFFGGKNKKY"
     CDS             complement(1012..2187)
                     /locus_tag="ctg25_4"
                     /transl_table=11
                     /translation="MRNEIYLFNPENDMALANFTPYYKAPSEIIRMANDLSVLPAWYAP
                     EGSTIKVDSLSRVSLWREQCPASDFLPDVIWSAEWENMPYKPWGWSPSLLYTLRKAGVN
                     DSFLLSDMQMGQIRVLSGRQCCVKILESFSRMDGLCGKAMTCNSMTQVKKYITSLERCV
                     LKAPWSGSGRGIMYVPSKEWNDSAEGWVSRVLRVQGEIMVEPLYNKVCDFAMEFYADGN
                     GCVSFVGYSLFDTDAHGNYKGNFLLSDGQIKKILSQYIPDEVFNNVCRTMEESLASLLN
                     KGYCGFLGVDMMICLEDGKYLLHPCVEINLRMNMGVVSHTIFNRYVHCLSHGKYIVKYY
                     SEDGEAWDAFCQMKATYKLHLCDGKLAEGYMPLTPVKQDTHYHAFLLLDRI"
     CDS             2300..3478
                     /locus_tag="ctg25_5"
                     /transl_table=11
                     /translation="MEVFYRTHNYLVEHTNAPVRRDLMDEIDWSARLIGIKGTRGVGKT
                     TFLLQYAKEKFGFDRSCLFVNMNNFYFSQCSLVDFAGEFVKRGGKVLLIDQVFKLPHWS
                     HDLRTCYERYPNLKIVFTGSSVMRLKDENPELNGIVRSYNLRGFSFREFLNLQTGNHFS
                     SYSLEEILNNHEHIAKTILPHTNPLNYFQDYIHHGFYPFFLEKRNFSENLLKTMNMMIE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPVAPNVSQLATDIQTSRATVMNYIKYLADAR
                     LINMVYPKGEVFPKKPAKIMMHNTNLMYSIYPVKVEEQDVLETFFVNSLWKDHKVNKGE
                     KGTSFIVDENLNFRICNEGYKFKNNPNIYYAMHKSELGHGNQIPLWLFGFLY"
     CDS             3525..7073
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_6"
                     /sec_met_domain="PFOR_II (E-value: 4.1e-18, bitscore: 57.1,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.4e-82, bitscore: 268.3,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.2e-32, bitscore: 102.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-12, bitscore:
                     38.6, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.3e-13, bitscore: 42.4,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00011, bitscore: 14.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 3.2e-25, bitscore: 79.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSCRQTGFAMLCEGSVQEVMDLAGVAHLSTI
                     KSRVPFLNFFDGFRTSHEIQKIEMLENEDLAPLVDQKALAEFRERALSPNKPVARGMAE
                     NPDHFFQHRESCNPFYEAVPAIVEEYMNEINKITGRNYGLFNYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGLVSVHLYRPFSAKHFLAAVPKTATRIAVLDRTKEPGANGE
                     PLYLDVKDCFYGQENAPLIVGGRYGLGSKDTTPAQILSVYENLALPTPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTNKYCQAYFSYDS
                     KKSGGFTCSHLRFGDHPIRSTYLVTTPNFVACHVQAYLHMYDVTRGLRKNGTFLLNTIW
                     EGEELAKNLPNKVKKYFAENNITVYYINATKIAQEIGLGNRTNTILQSAFFRITGVIPV
                     DLAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKQLTVDPAWASLEVEAAAANNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWHQGTAKYEKRGVAAFVPEWNPETCIQCN
                     KCAYVCPHAAIRPFVLDANEQAGANFPTLKAVGKQFDGMTFRVQVDVMDCLGCGNCADV
                     CPGNPKKGGKALTMKPLETQLAEAANWTYCAENVKSKQHLVDIKANVKNSQFAQPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNEKGQGPAWANS
                     LFEDFCEFGLGMELANKKLRNRLEEAMKAAIAAEGTPAEYKEAFQEWIDGRNDADKSKA
                     AAEKIIPMVEAAKDKCSYCATIAEFKDYLIKRSQWIIGGDGASYDIGYGGLDHVIASGE
                     DVNILVLDTEVYSNTGGQSSKATPLGAIAKFAASGKRVRKKDLGMIATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLVIAYAPCINHGLKAGMGKSQAEEAKAVECGYWHLWR
                     FNPALEEEGKNPFSLDSKEPNWEGFQDYLKGEVRFASVMKQYPTEAADLFAACEDMAKK
                     RYASYKRMAAMDWSEE"
     CDS             7429..7968
                     /locus_tag="ctg25_7"
                     /transl_table=11
                     /translation="MKYLIVSDIHGSLPALEKVLEFYKEQACHMMFILGDILNYGPRNS
                     IPEGINPKGIAERLNSMADEIIAIRGNCDSEVDQMLLDFPILADYALVADNGKRLFLTH
                     GHVYNEEKLPKGKHDYLFYGHTHLWKLEKKENMVICNTGSVTFPKGGNVPTFAIFEDGK
                     VSIYDLNGTKLKEVSK"
     CDS             complement(8085..9494)
                     /locus_tag="ctg25_8"
                     /transl_table=11
                     /translation="MWTSTLKKGLFLIGGLFLGGAVHAQYLRTSYFMEGASSRLQLNPG
                     LQPSGGYFNIPVLGSFNIGAYSDVLGMSDIVGVLDSGSDLFTNDDLYGRLKADNRLNVN
                     LNTDILSFGWYKGKGFWSVNVGLRTDIGASIPKNMFDYLRDADQFDLSRGTLQGNITDM
                     NFKVNAYAEVGLGYSRPVNDKLTVGGRVKVLLGVAHAEMQVDEFAVDMNIPQNPDDPNS
                     WNGTYGGSTTACAHIMTSIKGGGLSFADSYDSNGNAIRQIDGFDFDGGGFGIAGTGFGV
                     DLGASYKLLDNLNLSAAVLDLGFIKWNSSNTTVASVNENADVKIDQSNYQEYLNGDFLN
                     LERFNLAEDKEAASSYKTKLSSTLLLAGEYTFWDNKLSVGAMYGVHFVQPKALNELTFL
                     ATIRPKSWFNAALSYSPIQAGGKSFGLALKLGGLFIGTDYMYFGSNSKAVNGFIGLSIP
                     LGKNKPTDDAI"
     CDS             complement(9852..10604)
                     /locus_tag="ctg25_9"
                     /transl_table=11
                     /translation="MEKVYRTVIIDDEESAIDNLCFELQRYSYISVEGKAKTGTLGLKI
                     IERVRPDLVFLDVELPDMLGMDVVARLEGYVSWNMKIVFYTAHDRYVIDALRAKAFDFL
                     LKPVEPAELQTVLSRLCKPEYIVHNYMPPVTADAGKPFVVTTPTGDLRFLHTSEIGYFR
                     YQSARKIWEVALTNGTFLPLKRNTTAEQLCAYDTAFTQIHQSYIINLHYLIMVQDNRCI
                     MYPPFNSLEELVVSKKYKKKMIERFYQL"
     CDS             complement(10553..12649)
                     /locus_tag="ctg25_10"
                     /transl_table=11
                     /translation="MKGNKMCRLHLILLYVCLILCTGCISGERKDAHVVTDEWKIKQME
                     LLLENDPGTAMDKMDSLLPYLKDSMSYYRGIVFKSKAYMLMSRIGDASRMLRQAGSFCT
                     SPSEEDKSDLYASVCNMEGNILARQAKFDSARVKFLQAYELYMHTGNKLKRFNVMLNLA
                     DAFLREGACDKGALWYHRSLRLADSLGLPKSQCFPVYYGLGQVYMQLHDFERCDFYFDR
                     AGEYYDEMKPYEKGIYLNNRGNSYYYRQDYKTALKYFRRSLAHALAHPEMEYERNLTMI
                     NLGEVFLLMNQTDSASYYLSRCRDFFQKEDNNSALYYIDTQLIELALKEGNLSLAKKRL
                     DEAVVPDFVEPNMVHIRNRYLQHYFEESKDYRRAYYYLVENSRIDDSIRSERIKMRTQE
                     IAMKYRRDSILMKKEMLIQQAENKVLHLNQWLYGGEIVLLVFMLIAGAWIAYRSRKRDK
                     EEWMMRNAMTSLRLKNIRNRISPHFIFNVLNREISSLKDRESNHRLYELVKLIRYNLEL
                     TESLAVTLAEELDFVKTYIGLEEQVLQPGFEFHIDIDPALDIHRVKIPVMLLQIPVENA
                     VKHALSCKDGIRMLWIEVKKDKDCIKALVRDNGGGFKVKSNSYGTGTGMKVLSQTIQLL
                     NSYNRYPLIMQINNVEIKERGELGCEVKFTIPLDYSYLLGRAKDTNLWKRCIEQLSLMM
                     KRVQ"
     CDS             12816..13700
                     /locus_tag="ctg25_11"
                     /transl_table=11
                     /translation="MKNLSNDKISIQIADHGAELVSIYANGTEYLWQADPQFWGRHSPV
                     LFPIVGRVWNNTYRHKGQTYSLGQHGFARDMDFQLTYEEENAAIYTLESNEETMKVYPF
                     PFVLEIGYRLKGNRIEVMWSVQNTGDKDLHFQIGAHPAFYYRDLNPETNERGFLDFGKK
                     IKTLEYISPAEKGCVLPQRHTLTLHEGLMELRRDTFACDTYMFDNSQLKKITLLDKKQQ
                     PYISLEFNSPLVAVWSPSATYPNVPFVCIEPWYGRCDTVGYEGEFKDREWMQHLAPGKS
                     FEASYSIILEDIE"
     CDS             13721..14488
                     /locus_tag="ctg25_12"
                     /transl_table=11
                     /translation="MIIFQYDKTFEGLLTAVFEAYRLKKFPDSIIKEGDTLPLFYDETY
                     TVITDDEKAERVWKSLEKKLSKGALSMLTYSWLSEASDIAIVLFRYIRKITDASRSIET
                     NFADPDILTISKLGKKVADERYRILQFMRFQKTTEGIYYGAMEPLYDVFPLTIRHFRDR
                     FADQKWLIYDVKRHYGYYYDGKEVNEITFADPKQTHLQTGKLDESLLDKNEKLFQTLWK
                     SYFKSICIKERLNPVKHKKDMPVRYWKYLTEKN"
     CDS             complement(14491..15249)
                     /locus_tag="ctg25_13"
                     /transl_table=11
                     /translation="MFRYFIYLAYDGANYHGWQIQPNGNSVQETLTRALITFLRDDAIE
                     VTGAGRTDAGVHARLMVAHFDIERMLDCDSVTDKLNRLLPPDISVYQVRRVRQDAHARF
                     DATYRTYKYYITTRKDPFNRNYAWRVFQSLDFDKMNEAAKVLFEYTDFTSFSKLHTDVK
                     TNNCRIMHARWEQIGEDEWVFTIQADRFLRNMVRAVVGTLVEVGRGKLTVEGFRKVIEE
                     KNRCSAGTSVPGHALFLVDIGYPDDLFAVC"
     CDS             complement(15256..15897)
                     /locus_tag="ctg25_14"
                     /transl_table=11
                     /translation="MIALVAAGILGSCGHEDKSIKLNNPRNIRGVVSYKRSFGDLNDVQ
                     LASARRIGIRPISSREAAVDLDGDLKEIVSCERYDVDSLTHSIPFLVPRAAALLDTLGI
                     NFLDSLESKGLNPNKIIVTSVLRTKDDVKKLRRTNGNASLNSCHFYGTTFDVSWKRFTK
                     VEDPGGRPMQDVSADTLKLVLSEVLRDLRKAERCYVKYELKQGCFHITTR"
ORIGIN
        1 ctcattttat ttactgccag agccgcttag gcttggcgaa tttttaacga actattaaat
       61 gtaataacaa taaagaccat acttatgaaa gcattaaacg tagtagctgc attcttaggt
      121 ggactagcat taggagcagc agcaggtgtt ttattcgcac cagaaaaagg tgaagatact
      181 cgtagcaaaa ttgcagaact tttacgtaaa aagggaatcc gactgaaccg tgaagaaatg
      241 gatgatttgg tagaccaaat cgcatcagaa gtaaaagatg cagaataacc gaattaatga
      301 aaaccaaagg cagactttta cagaaacgaa tgaaaaagtc tgcctttctt catctaaaaa
      361 ccaatgccta tgtttgctaa tgataaaagc atcgacaatc taactgaatt atttaaagaa
      421 gtaaagaaat atctaaaatt acaaggagaa tatgtcaagt tagacttagt agaaaagcta
      481 actattctgt tatctactct gacccttata tttgtcctta ttatattagg cacaatggca
      541 gcattctacc tttcttttat gctggtatat gtattagcat cggctacagg cagtttagtt
      601 gccggatatg ctattatagg cggaatactc atattacttg cgtttataat ttacagattg
      661 cgccaaaaat taatatttca gccaatggtt aattttttag caagattatt tttagatgac
      721 tcttccaaca actcacttta agtttcaaac aatgaaaaca gaacagccta ttacatacag
      781 tattgaaagt atcagagaac gtagacttgc caaacaagaa gaattgaaac tttccaaaga
      841 ccgaatgcat aatctgtcac aacaattatt tgcccctcag caaggtcaga acaaaataga
      901 cagtttaatg caacaaatca atatgggtat tgctgcatat gatggtttaa tgaccggtat
      961 caaaatatta cgtagagtac ggggattctt tggaggaaag aataaaaaat attaaatcct
     1021 gtctagtaac aaaaatgcat gataatgcgt atcctgcttc acaggagtaa gaggcatata
     1081 tccttcagcg agtttaccat cgcataaatg caatttataa gttgccttca tttgacaaaa
     1141 tgcatcccaa gcctctccat cttcagaata atatttcaca atatacttac catggcttaa
     1201 gcaatgcaca taacgattga atatcgtatg tgatacgact cccatattca tacgcaaatt
     1261 aatctctaca caaggatgaa gtaaatattt tccatcttct aaacagatca tcatatctac
     1321 tcccaaaaat ccacaataac ctttattcaa cagcgaggca agactttctt ccatagtccg
     1381 gcaaacatta ttaaaaacct catcaggtat atactgcgac agaatctttt ttatctgtcc
     1441 atctgataat aaaaaattcc ccttgtagtt tccatgtgcg tcagtatcaa acagagagta
     1501 gccaacaaaa ctaacacaac catttccgtc cgcataaaac tccattgcaa aatcacatac
     1561 cttattatat aaaggttcta ccataatttc gccctgcacc cgcaatacac gcgacaccca
     1621 tccctcagca gagtcattcc attccttaga aggcacgtac ataatacctc ttccacttcc
     1681 tgaccacgga gcttttaaga cacatctttc caaagaagta atatactttt tcacttgggt
     1741 catagaatta catgtcattg ccttaccaca taaaccatcc atgcgcgaaa agctctccaa
     1801 tattttcaca caacattgcc gtccagaaag tactcttatt tgccccatct gcatatccga
     1861 caaaagaaag ctatcattta ccccagcctt ccttaaagta taaagcaaag aaggactcca
     1921 gccccatggt ttataaggca tattttccca ttcagcactc catattacat caggaagaaa
     1981 atctgacgcc ggacactgtt ctctccacaa agacacacgt gacaaggagt ctacttttat
     2041 cgtacttcct tctggtgcat accatgcggg aagcacagat aaatcattcg ccatacgaat
     2101 tatttcagaa ggagctttat aataaggagt aaaattggct aaagccatat cattttccgg
     2161 gttaaagaga taaatttcgt ttcgcataaa aacacttttt ttacaagata caaagttaac
     2221 gtaaaaaaga atattttgtc aactccagtt tgcaaattga tgaactatta ctatatttgc
     2281 accgaagaaa cagagattca tggaagtatt ttacagaaca cataattatt tggtcgaaca
     2341 taccaatgcc cctgtgcgac gcgacctgat ggatgaaata gattggagtg ctcgcttgat
     2401 aggtatcaaa ggtacacgag gagtaggtaa aacaacattc ttattgcaat atgcaaaaga
     2461 aaaatttggt tttgatcgct catgtttgtt cgtaaacatg aataacttct atttctctca
     2521 atgcagtctg gtcgattttg ccggcgaatt cgttaagcga ggaggtaaag tgctgcttat
     2581 cgaccaagta ttcaagttgc ctcattggag tcatgatttg cgtacttgtt atgaacgcta
     2641 ccctaattta aaaattgttt ttacgggttc ttctgtaatg cgcctgaaag acgaaaatcc
     2701 agagctgaat ggaattgtcc gttcctacaa tctacgcgga ttttcattca gagagttctt
     2761 aaatctccaa acaggcaatc atttttcttc ttattcattg gaagaaatat tgaataacca
     2821 cgaacatata gctaaaacaa tattacctca cacaaatccg cttaactatt ttcaagacta
     2881 catacatcat ggattttatc ctttttttct ggaaaaaaga aacttctcag aaaacttatt
     2941 aaaaaccatg aatatgatga tagaagtaga catacttctt atcaaacaaa ttgaactaaa
     3001 atatctatcc aaaataaaaa aattattata tttgttggca gtggatggtc cagttgcccc
     3061 taatgtcagt caactggcta ccgacataca aacctctcgt gctacagtaa tgaactatat
     3121 caagtatctt gccgacgcac gactcataaa tatggtttat cccaaaggtg aggtcttccc
     3181 caaaaagccg gctaaaatca tgatgcataa tacaaatctg atgtacagta tttatccggt
     3241 aaaagtagaa gagcaagatg ttctggaaac atttttcgtt aattcactat ggaaagacca
     3301 taaagtaaac aaaggagaaa aaggaacatc tttcatagta gacgaaaatt taaacttccg
     3361 catttgcaat gaaggatata agttcaagaa caatcctaat atctattatg ccatgcataa
     3421 atcagaatta ggacatggaa accaaatacc tttatggttg ttcggttttc tttattaacg
     3481 tttaacggca cagattttat tacctaaata taattagtaa ttgtatgact aaacaaaaaa
     3541 aattcatcac ttgtgatggt aaccaagctg cagcacatat ttcatatatg ttctcagaag
     3601 ttgcagctat ttatcctatc accccatctt ctacaatggc tgaatatgta gacgaatggg
     3661 cagccgcagg tcgtaaaaac atcttcggtg aaactgtttt ggttcaagaa atgcaatctg
     3721 aaggtggtgc tgctggtgct gtacatggtt ctcttcaggc tggtgcattg acaactactt
     3781 atacagcttc tcagggtctt ctgttgatga ttcctaacat gtacaaaatt gcaggtgaat
     3841 tcttgccttg cgtattccat gtatcagctc gtacattggc ttcacatgca ttgtgtatct
     3901 tcggtgacca ccaagatgtt atgtcttgcc gtcagactgg tttcgctatg ctttgcgaag
     3961 gttctgtaca ggaagttatg gatttggctg gtgtagctca cttgtcaaca atcaaatctc
     4021 gcgttccatt cctgaacttc ttcgacggtt tccgtacctc tcatgaaatt cagaagattg
     4081 aaatgcttga aaacgaagat ctcgctccgc tggtagacca aaaagcttta gctgaattcc
     4141 gtgaacgcgc acttagccct aacaagccag ttgctcgtgg tatggctgaa aacccagatc
     4201 atttcttcca acacagagaa tcttgcaatc cgttctatga agcagttcct gctatcgtag
     4261 aagaatatat gaatgaaatc aataagatta caggacgtaa ctatggtttg ttcaactact
     4321 atggtgctga agatgctgaa cgcgtaatca tcgctatggg ttctgtaaca gaagctgctc
     4381 gtgaagctat cgaccacttg gtagctaatg gcgaaaaagt tggtttggtt tcagttcact
     4441 tgtatcgtcc gttctctgct aaacatttct tggcagctgt acctaagact gctacacgta
     4501 ttgcagttct tgaccgtaca aaagaaccgg gtgcaaacgg cgaacctttg tatcttgacg
     4561 taaaagactg cttctacgga caggaaaatg ctcctcttat cgtaggtgga cgttacggtt
     4621 tgggttctaa ggatacaact cctgctcaga ttctttctgt atacgaaaac ttggcattgc
     4681 caactcctaa gaaccacttc actatcggta tcgtagatga cgttacattt acttctcttc
     4741 cacaaaaaga agaaatcgct ttgggtggcg aaggtatgtt cgaagctaaa ttctacggtc
     4801 tgggtgctga cggtactgta ggtgctaaca agaactctgt taagattatc ggtgacaaca
     4861 ctaacaaata ctgccaggct tacttctctt atgactctaa gaagtcaggt ggtttcactt
     4921 gctctcactt gcgtttcggt gatcatccta tccgttctac ttacttggta actactccta
     4981 actttgtagc ttgccacgta caggcttatc tgcacatgta cgatgtaact cgcggtctgc
     5041 gtaagaacgg tacattcttg ctgaacacta tttgggaagg cgaagaattg gctaagaacc
     5101 tgcctaacaa ggttaagaaa tatttcgcag aaaacaatat cactgtttac tatatcaacg
     5161 caactaagat tgctcaggaa attggtttgg gtaaccgtac caacactatc ctgcagtctg
     5221 cattcttccg tatcacaggt gtaattcctg ttgacttggc tgtagaacag atgaagaaat
     5281 tcatcgttaa gtcttacggt aagaagggtg aagatgtagt taacaagaac tacgctgctg
     5341 ttgaccgtgg tggtgaatac aaacaactga cagtagatcc tgcatgggct agcttggaag
     5401 ttgaagctgc tgctgcaaac aatgatccag cattcatcaa cgaagttgtt cgtcctatca
     5461 acgctcagga cggtgacttg ttaccagtat ctgcattcaa gggtatcgaa gacggtacat
     5521 ggcatcaggg tacagctaaa tacgaaaaac gtggtgtagc tgcattcgtt ccagaatgga
     5581 atcctgaaac ttgtattcag tgtaacaagt gtgcttatgt ttgtcctcac gctgctatcc
     5641 gtccattcgt attggatgca aacgaacagg ctggtgcaaa cttcccgaca ctgaaagctg
     5701 taggaaaaca gttcgacggc atgacattcc gtgtacaggt agacgttatg gactgcttgg
     5761 gttgcggtaa ctgtgctgac gtatgtccgg gtaacccgaa gaagggtggc aaggctctga
     5821 caatgaagcc gcttgaaact cagttggctg aagctgctaa ctggacttac tgcgctgaaa
     5881 acgtgaagtc taaacagcac ttggtagaca tcaaggctaa cgttaagaac tctcagttcg
     5941 ctcagccatt gttcgagttc tctggcgctt gctctggttg tggtgaaact ccatacgtta
     6001 aattgatttc tcagttgttc ggtgaccgtg aaatggttgc taacgctact ggatgttctt
     6061 ctatctactc tggttctgtt ccttcaactc cttacacaac aaacgaaaaa ggtcagggtc
     6121 ccgcttgggc taactcattg ttcgaagact tctgcgaatt cggtttgggt atggaattgg
     6181 ctaacaagaa actgcgtaat cgtctggaag aagctatgaa agctgctatc gctgcagaag
     6241 gtactccagc agaatacaaa gaagcattcc aggaatggat cgacggccgc aacgatgctg
     6301 ataagagcaa agctgctgct gaaaagatca tcccgatggt ggaagctgca aaagataaat
     6361 gctcttactg cgctactatc gctgaattca aggactatct gatcaaacgt tcacaatgga
     6421 ttatcggtgg tgacggtgct tcatacgata tcggttacgg aggtttggat cacgttatcg
     6481 cttctggcga agatgtaaac atcctggtat tggatactga agtttactct aacactggtg
     6541 gtcagtcatc taaggctact cctctgggtg ctatcgctaa gttcgctgct tcaggtaaga
     6601 gagtacgtaa gaaagacttg ggtatgattg ctactactta cggttatgtt tacgtagctc
     6661 agattgctat gggtgctgac caggctcaga ctttgaaagc tatccgcgaa gcagaagctt
     6721 atccaggtcc atcattggtt atcgcatatg ctccatgtat caaccacggt ttgaaagctg
     6781 gtatgggtaa atctcaggct gaagaagcta aggctgtaga atgtggttac tggcacttgt
     6841 ggcgcttcaa cccagcattg gaagaagaag gtaagaatcc gttctcactt gactctaaag
     6901 aaccaaactg ggaaggcttc caagactact tgaagggtga agttcgtttc gcttctgtaa
     6961 tgaaacagta tcctactgaa gctgcagact tgttcgctgc ttgtgaagac atggctaaga
     7021 aacgttatgc ttcttacaag cgtatggctg caatggactg gagtgaagaa taattctcct
     7081 gttttattaa acaagtattc tgataaataa taaaagagat tcaagaacta tttcttgaat
     7141 ctctttttta tttatccatt ctcctcattt cctcaccaat attacagcta ctgattacta
     7201 taaaaacata ataataagat atcattgctg tgcgatattt ttctaatcat caataactta
     7261 ttgacacaat aaaattaagc agtaacttta acaagggaac ttatctataa aaacaatact
     7321 ttttaataat atctgttttt ttctaataac accgaaaata tcgtaaaaat acttctgtat
     7381 gttttcagaa aactttctat ttttgcgcaa atttataata acattatcat gaaatattta
     7441 attgtatccg acatacatgg ctcactgcca gccttggaaa aagtcttaga gttttataaa
     7501 gagcaagctt gccacatgat gttcatacta ggtgatatct tgaattatgg cccccgaaac
     7561 agcatccctg aaggaattaa tcccaaagga atagcagaac gcctcaacag catggcagat
     7621 gaaattattg ccatacgagg caactgtgat tctgaggtag atcagatgct gctcgatttt
     7681 cctattctag cggattacgc tttggtagca gataacggaa aacgactttt cctgacacat
     7741 ggacatgtat ataatgagga gaaacttcca aagggaaaac atgattacct cttctacgga
     7801 cacactcact tgtggaaact tgaaaagaaa gaaaatatgg tgatatgtaa cacaggttct
     7861 gtcactttcc ccaaaggtgg aaatgtacct acgtttgcaa tattcgaaga tggaaaggtt
     7921 tctatttatg acttaaacgg tacgaaactg aaagaagtaa gtaaataaaa aaagagaagg
     7981 ctgtttctca ttatcatagt tctaagacag acaagaacaa gaaccatgaa atgagcagac
     8041 agcccctcta taaaaaaatc ttagaatata acttatcatc tatatcaaat agcatcatcg
     8101 gtgggtttat tctttcccaa tggaatcgac aaacctataa atccattaac agccttggag
     8161 ttgctgccaa aatacatata atcagtacca ataaacaatc ctcccagttt taaggcaagt
     8221 ccgaatgatt ttccgcctgc ctgaatagga gaataactta gagctgcatt aaaccagctt
     8281 ttcggacgta tagttgccaa gaacgtaagt tcatttaatg ctttaggctg aacaaagtgt
     8341 acaccataca tagctccaac actcaactta ttgtcccaaa atgtatattc accagctaac
     8401 agaagtgtag acgatagttt tgttttatat gaagaagcag cttctttatc ttcagccaaa
     8461 ttaaaacgtt caagattaag gaaatctcca ttcaaatatt cctgataatt gctttggtcg
     8521 attttgacat cggcattttc gtttacagaa gctacagtcg tattgctgct gttccatttt
     8581 atgaagccta aatcgagtac agcagctgat aggttcaggt tgtcgagtaa cttatagctt
     8641 gctcccaaat caactccgaa tccagtaccg gcaataccaa aacctcctcc atcgaagtcg
     8701 aatccgtcaa tctgacggat agcatttcca ttactgtcat acgaatcggc gaaactaagt
     8761 ccacctcctt ttattgaagt cataatatgc gcacatgccg ttgtagaacc accgtatgta
     8821 ccattccaac tattaggatc atccggattc tgaggtatat tcatatctac agcaaattca
     8881 tcaacttgca tttctgcatg agcaacacct aacagaacct ttacacgtcc tccaacagtc
     8941 aatttatcat ttacaggacg agaataccct aatccaacct cagcatacgc attcacttta
     9001 aagttcatgt ctgtaatatt accttgaagg gttccgcgac ttaaatcgaa ctgatctgca
     9061 tcacgcaaat aatcaaacat gtttttagga atagaagctc caatatcggt acgcaaacct
     9121 acatttacac tccaaaaacc ttttcctttg taccatccaa aagacaagat atctgtattc
     9181 agattaacat tcaaacggtt gtccgcttta agtcggccat acaagtcatc attagtaaac
     9241 aaatctgaac cagagtcgag aacacccaca atatcactca tacccaacac atcagaatat
     9301 gctcctatat tgaacgaccc caaaaccgga atattaaaat atcctcccga tggttgtaaa
     9361 cccggattca actgcaagcg tgaacttgct ccttccataa aataagaggt acgaagatac
     9421 tgagcatgta ctgctccccc taagaacaat cccccaatta aaaataaacc tttttttaat
     9481 gtactagtcc acataattac tctctattat ttaacggatg caaaaataag aattttcctg
     9541 ttaacaaaaa gttacaaaaa acagattgtt ggactatgta gaactaatca tgtactaaac
     9601 atacaaaaaa cgcgactatg tgaaaaatat tctgtctatg tcattacccg atatgttcgg
     9661 ctaaccatca ataaaagatc caaatatcaa gctacagtca agcataaaac ctcagcaaaa
     9721 cacctgattt tttcgtacaa agattccgga caattgtacg aattttaaaa aaatatcagc
     9781 atgtttttcc taaaatatgc tgatatttta gacagaatat cctgcacttg tttcaagcag
     9841 atatttttgt ctcaaagttg ataaaaacgc tctatcattt tctttttata ctttttagaa
     9901 acaacaagtt cttccaaaga attaaaaggt ggatacatga tacagcgatt atcttgaacc
     9961 ataataagat aatgtaaatt gataatatac gactgatgta tttgagtgaa agcagtatcg
    10021 tatgcacaaa gctgttcggc agtagtattt ctttttaaag ggagaaaagt tccattggtc
    10081 aatgctactt cccaaatctt ccgcgcagac tgataacgga aataaccgat ttcagaagta
    10141 tgcaaaaaac gtaagtcacc agtaggagtt gttaccacaa acggttttcc ggcatccgca
    10201 gtaacaggag gcatatagtt atgcactata tattcaggtt tacacagacg tgacagaaca
    10261 gtctgaagct cagctggttc tactggcttt agaagaaaat cgaaagcctt tgcccgaagt
    10321 gcatcaatca catatctgtc gtgtgcagtg taaaacacga ttttcatatt ccaggaaaca
    10381 tagccctcca gtcttgccac tacatccata cccagcatat cgggtagttc tacatccaaa
    10441 aacactaaat caggacgaac tctctctatt attttcaatc ctaatgtacc agtctttgct
    10501 ttaccctcta ccgaaatata agaataacgt tgtaactcaa agcacaaatt atctattgca
    10561 ctctcttcat catcaatgat aactgttcta tacacctttt ccataaatta gtatcctttg
    10621 ctcttcctaa cagatatgaa tagtcaagcg gaatagtaaa cttaacttca catcctaact
    10681 ctcctctttc ttttatctca acattgttta tttgcataat caacggataa cggttgtacg
    10741 aattcagtaa ctgaatagtc tgcgacagca ctttcatccc agtaccagtt ccgtaactgt
    10801 tgcttttcac tttaaagcct ccaccattat cacgtaccaa agccttaata caatctttat
    10861 ctttttttac ttcaatccac aacatccgga ttccgtcctt acaacttaaa gcatgtttta
    10921 ctgcattttc aacagggatc tgtaataaca tcacaggtat cttcacccta tgtatgtcta
    10981 atgctggatc tatatcaata tgaaattcaa atcccggttg taaaacttgc tcctcaaggc
    11041 caatataagt cttcacaaaa tccaattctt ctgctaaagt tacagccaga ctttccgtca
    11101 attccagatt atatcttatt aacttaacca gctcatataa acggtgatta ctttctctat
    11161 cttttaaaga gcttatttct ctgttcagta cattaaaaat aaaatgcggc gaaatacggt
    11221 tacgaatatt tttcagtcgc aaagacgtca tggcatttct catcatccac tcttctttgt
    11281 cccgcttgcg acttcgataa gctatccatg ctccagcaat aagcataaat accaataaca
    11341 caatttcccc tccgtacagc cactgattta aatgaagcac cttattttct gcctgttgaa
    11401 taagcatttc ttttttcatc aaaatactgt cacgacgata cttcatagca atttcctgtg
    11461 tacgcatttt tatacgctca cttcgtatag aatcatctat ccggctattt tccaccaaat
    11521 aatagtaagc acgacgataa tctttacttt cctcaaaata atgttgcaaa taacggttac
    11581 ggatatgtac catgttaggc tctacaaaat ccggaaccac agcctcatcc agacgtttct
    11641 ttgcaagcga cagatttcct tctttcagag ccagttcaat aagttgcgta tcaatataat
    11701 aaagagcact attattatct tctttttgaa agaaatcacg acatcttgac aaataataag
    11761 aggcggaatc ggtctgattc atcagcaaaa atacttcgcc caagtttatc attgtcaagt
    11821 tacgctcata ctccatttca ggatgcgcca aggcatgtgc caacgaacga cgaaaatatt
    11881 ttaacgctgt tttataatcc tgacgataat aataagaatt acctctgtta ttcagataga
    11941 tacctttttc ataaggtttc atttcatcat agtactctcc agcacggtcg aaataaaaat
    12001 cacaccgttc aaaatcgtgc aactgcatat aaacttgtcc cagtccataa tatacaggaa
    12061 agcactgact tttaggcaaa cccaatgaat cagccaatct cagcgaacga tgataccaca
    12121 aagctccttt atcacatgct ccctcacgaa gaaaagcatc ggccagattc aacataacat
    12181 tgaatcgctt taacttatta cccgtatgca tataaagttc atatgcctga agaaatttaa
    12241 ctcgtgcaga gtcaaacttt gcctgacgcg ccagtatatt tccctccatg ttacagacag
    12301 aagcatataa atcgctttta tcttcttcag aaggagaagt acaaaacgaa ccagcctgcc
    12361 gaagcatacg agatgcatca ccgatacgtg acatcaacat ataagctttc gacttaaaca
    12421 caatgccacg gtaataagac atgctgtctt tcagataagg cagcagacta tccattttgt
    12481 ccatagctgt ccccggatca ttttccagca acaattccat ctgctttatc ttccattcat
    12541 cggtgacaac atgagcatct tttctttcgc cggaaataca acctgtacac aatattagac
    12601 aaacatataa taatataagg tgtaatctac acatcttatt tcctttcatc ccgattaaca
    12661 agacaaatgt atgtaaaaac aatcaacata caaaaataag tttaaaaatt atacacaacc
    12721 atcctataaa atcattactt ttgaatagtg gattttaact acactatttc aatcaatgaa
    12781 caacaagaat aaactaacaa taaaaaatag aatatatgaa aaacctgtcg aacgataaaa
    12841 tcagtattca aattgccgat cacggtgcag aactggtaag tatttatgca aacggaaccg
    12901 agtatttatg gcaagccgat cctcaatttt ggggacgtca ttctcctgta ttgttcccga
    12961 tagtaggacg agtatggaat aatacctacc gtcataaagg acaaacatat tcgttaggac
    13021 aacacggatt tgcccgcgac atggacttcc agcttacata cgaggaagaa aatgcagcaa
    13081 tctatacctt agaaagcaac gaagagacaa tgaaagtata tccatttcct ttcgtgctcg
    13141 aaataggata ccgcctgaaa ggcaaccgta ttgaagtaat gtggagtgta caaaatactg
    13201 gcgacaaaga ccttcatttt cagataggtg ctcatccggc attttactac cgtgacctga
    13261 atcctgaaac aaatgaaaga ggattcctcg attttggaaa aaaaatcaaa acattagagt
    13321 atatttctcc tgcagaaaaa ggatgtgtac tacctcagcg tcataccttg accttgcatg
    13381 aaggtctgat ggaattaaga cgagatacat ttgcatgcga tacgtacatg ttcgacaata
    13441 gccagctgaa aaaaataact cttctggata aaaagcaaca accatacatc agtctggaat
    13501 tcaacagtcc gctggttgca gtatggtcac caagcgcaac ttatcccaat gttccttttg
    13561 tatgtatcga accctggtac ggacgttgtg acacagtagg ttatgaagga gaattcaaag
    13621 acagagaatg gatgcagcat cttgctcccg gaaaaagctt tgaagcaagt tactctatca
    13681 ttctggaaga tatcgaataa cacctatcta tccggaatct atgataattt tccagtacga
    13741 taaaacattt gagggacttc ttacagctgt atttgaggca tacagactta agaaattccc
    13801 cgattctatc ataaaagagg gagacactct ccctcttttt tatgatgaaa catatactgt
    13861 tataactgat gatgaaaaag cggaacgagt ctggaaatca ttggaaaaaa agttatcaaa
    13921 aggagcactc tccatgctaa cttacagctg gctgtcggaa gcttccgaca tagctatcgt
    13981 gctattccgt tatatacgga aaataactga cgcttcacgc tcaatagaaa ctaattttgc
    14041 agatcctgat attcttacca tttcaaaatt agggaaaaaa gtagccgatg aacgttaccg
    14101 cattttacag ttcatgcgtt tccagaaaac taccgaaggc atatattacg gagccatgga
    14161 accgctatat gatgtgtttc ctcttactat ccggcatttt cgtgatcgtt ttgccgatca
    14221 gaaatggctt atttatgatg taaaaagaca ttacggttac tattatgatg gaaaagaagt
    14281 aaatgaaatc acatttgcag atcctaaaca gacgcatctg cagacaggaa aactggacga
    14341 aagtctgctg gataaaaacg aaaagctttt ccaaacatta tggaaaagct attttaaatc
    14401 tatctgtatc aaagaaagat tgaatcctgt caagcataaa aaagacatgc cggtacgata
    14461 ctggaaatat ctgacagaaa agaattagcc tcaacaaaca gcaaacaagt cgtcgggata
    14521 gccaatatca acaagaaata aggcatgtcc cggaaccgat gtacctgcac tgcagcgatt
    14581 cttttcttct attaccttac ggaatccctc tacagtaagt ttacctcgtc ccacttccac
    14641 cagtgtacca actacggcac gaaccatatt acgcaagaaa cggtcggctt gaatagtgaa
    14701 tacccattca tcttccccta tctgttccca acgtgcatgc atgatacggc aattgtttgt
    14761 ctttacatct gtatgcaatt tactgaagct ggtaaaatct gtatactcaa acaaaacctt
    14821 tgctgcctca ttcatcttat caaaatccaa tgactgaaaa actctccagg cataattccg
    14881 gttgaaggga tctttacggg ttgtgatata atatttataa gtgcgataag tcgcatcaaa
    14941 acgggcatga gcatcttgtc ttaccctgcg aacctgatat acagatatat ctggaggcag
    15001 taaacgattc agtttgtctg tcacactatc acaatccagc atccgctcga tatcaaaatg
    15061 agctaccatc aggcgggcat gtactccagc atctgttctt ccggcaccag ttacttctat
    15121 tgcatcatca cgcaaaaaag tgataagtgc acgagtcaat gtttcctgca cactattgcc
    15181 atttggctga atctgccagc catgataatt ggcaccatcg taagctaaat aaataaaata
    15241 tctgaacatt tctgattatc ttgtcgttat gtgaaaacat ccctgcttca attcatactt
    15301 tacgtagcag cgttctgctt tgcgcaaatc acgcaagact tccgacagga ccagtttcag
    15361 tgtatcggcg ctcacatctt gcatcggacg tccgcctgga tcctccacct tagtaaaacg
    15421 tttccagctt acatcgaaag tagtaccata aaaatgacag gagttcaacg acgcatttcc
    15481 gttagtacga cgcagttttt tcacatcatc cttagtacgt aaaacagaag ttacgattat
    15541 tttattaggg ttcagtcctt tactttccag agaatccaga aaatttatac caagggtatc
    15601 cagtaaagct gctgcacgag gaacaagaaa cggtatggag tgagtcaggg aatctacatc
    15661 atagcgttcg cacgatacga tctcttttaa atcaccatcc aagtcgactg ctgcttcacg
    15721 cgaggatata ggacgtatcc ctatacggcg tgcagaagcc agctgtacat catttaaatc
    15781 accaaaactt cttttgtaac tcaccacccc acgaatattg cgtggattat tcagtttgat
    15841 agacttgtct tcatggccac agctacccaa tataccagct gcaaccaaag ctatcataca
    15901 tgttattcct gttagtcttt tcatgtttcc agtcaatctt tttcccaaaa ttcatagaaa
    15961 atacaagggc acaaagataa aaaagaaagc tgtcttttaa aaattcatga agagaaactt
    16021 ccttagttca cctcacattg cggtaatcgt acaacagata gacagaaaac agctggcaga
    16081 aagcagaaat taatttaccg tatatcgtgt acagataaaa aggaatgatt aaatttgcag
    16141 aaaaataaac aaacgagcat atcaaaataa tctgaatgat cgaaaaacat attgtattag
    16201 aagatattga tccggttatt ttttacggtg taaacaatgc caatatgcaa atgattaagg
    16261 cattgttccc caagttacgc attgtggcac gcggagatgt cataaaagta atgggggatg
    16321 aagaagaaat gtgtgcattc gaagaagcaa tactcgcttt ggaaaaacat tgcgcacgtt
    16381 ataattcgct gaacgaagaa gcgatattgg acatcataaa aggaaacaaa ccgcaaatcg
    16441 aaaagaccgg cgatgtaatt gtatatagcg tcaccggaaa acccattacc ccccgaagta
    16501 ccaaccagct gaaactggta aaagaattcg ataagaatga catgatcttt gctatcggtc
    16561 cagccggatc gggtaaaacg tatactgcta tcgcattggc agtacgtgct cttaagaata
    16621 aagaaatcaa aaaaatcata ttaagccgtc cggcagtaga agcaggcgaa aagttaggtt
    16681 tcttgcctgg agatatgaaa gacaagatag acccttatct gcaaccattg tacgatgccc
    16741 ttcaggatat gatacctgct gccaaactga aggaatacat ggagctgaac atcatacaga
    16801 ttgctcctct tgctttcatg cgtggacgaa cattaaatga tgcaattgtc atccttgacg
    16861 aagcacaaaa cactaccaca caacaaatca agatgtttct tacccgaatg ggtatgaata
    16921 ccaaaatgat cgttacaggg gatatgacac agatagacct tccctcatca caaacatcgg
    16981 gactggtaca ggctatcaag attcttaaag gtgtaaaagg tatcagcttc atagaactga
    17041 acaagaaaga cattgtacgc cataagctgg taa
//
