LOCUS       NZ_LR699011.1          25291 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LR699011.1 Roseburia hominis isolate MGYG-HGUT-02517 chromosome
            1.
ACCESSION   NZ_LR699011
VERSION     NZ_LR699011.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:08:44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 590505
            Orig. end    :: 615796
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25291
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[600505:605796]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15291
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..25291
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25291
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="acetate2butyrate"
                     /region_number="3"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             749..1834
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_524"
                     /sec_met_domain="GATase (E-value: 5.9e-47, bitscore: 157.5,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAFLILEDGNVFTGTSIGSTREVISEIVFNTSMTGYLEVLTDPS
                     YAGQAVVMTYPLIGNYGITPDMESGRPWPDGYIVRELSRMPSNFRCEGTIQDFLAKYDI
                     PGIAGIDTRALTKILREKGTMNGMITTNENYNIEEIIPKLKAYTTGNVVDKVTCTEKRV
                     LKKQGNAPETKKVALLDLGAKRNIVQSLRERGCEVTVYPAHTSAEEILAANPDGIMLSN
                     GPGDPKECKEIIAEIRKLYESDTPIFAICLGHQLMALATGADTHKMKYGHRGGNHPVKD
                     LATNRVYISSQNHGYVVDTDTLDPKVATPAFVNVNDGTNEGLSYVGKNIFTVQFHPEAC
                     PGPQDSAYLFDRFINMMGGAK"
     CDS             1834..5040
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CPSase_L_D2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_525"
                     /sec_met_domain="CPSase_L_D2 (E-value: 1.5e-81, bitscore:
                     270.5, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRNQEIKKVLVIGSGPIVIGQAAEFDYAGTQACRSLKEEGVEVV
                     LVNSNPATIMTDKDIADQVYIEPLTVPVLEQIIAKEKPDSILPTLGGQAGLNLGMELSE
                     KGILDKYGVKLIGTTAETIFKAEDRQAFKDTMEKIGEPCAASEVVHNVQDGIKFTNTIG
                     YPVVLRPAYTLGGSGGGIAHDETELIEILTNGLRLSRVGEVLVERCIAGWKEIEYEVMR
                     DANGNCITVCNMENIDPVGVHTGDSIVVAPSQTLGDKEYQMLRTSALNIISELNITGGC
                     NVQYALNPESFEYCVIEVNPRVSRSSALASKATGYPIAKVAAKIALGYTLDEIKNAITG
                     KTYASFEPMLDYCVVKIPRLPFDKFITAKRTLTTQMKATGEVMSICNNFEGALMKAIRS
                     LEQHVDSLMSYDFTGLSREELVKQLHVVDDRRIWVIAEALRRGMDYDVIHDITKIDKWF
                     IDKLAILVEMEQKLKSEPLTVELLKEAKRIEFPDKVIAELTGKTETEIHDMRYANGIVA
                     AYKMVDTCAAEFEATTPYYYSVFGSENEAEETHPNKKVLVLGSGPIRIGQGIEFDYCSV
                     HCTWAFAKEGWETVIVNNNPETVSTDFDIADKLYFEPLTPEDVEAIVKLEKPDGAVVQF
                     GGQTAIKLTESLMKMGVKILGTKAEDVDAAEDRELFDEILEKTKIPRAAGGTVFTAEEA
                     KEVANRLGYPVLVRPSYVLGGQGMKIAFNDDEIEEFIGIINRIAQDHPILVDKYLQGKE
                     IEVDAVCDGTDILIPGIMEHIERTGVHSGDSISVYPAPTISDHVKETIVEYTKRLAQAL
                     HVIGLINIQFIAMNEEVYVIEVNPRSSRTVPYISKVTGIPIVDLATKVIIGNTIRGLGY
                     EPGLAPTADYIAIKMPVFSFEKLRGAEISLGPEMKSTGECLGIAKTFNEALYKAFLGAG
                     VTLPKYKQMIMTVKDADKPEAVGVAKRFEALGYKIYATRSTAKYLQEHGVNALRVNKIT
                     QESPNVMDLILGHKIDLVIDTPTQGNGDKTRDGFLIRRNAIETGVYCITAMDTANALAR
                     SLETAMDTLTPVDIAKVKNL"
     CDS             complement(5295..5396)
                     /locus_tag="ctg1_526"
                     /transl_table=11
                     /translation="MLAKIKAFFMENIDGVAMGVEAMYGVDIHPYYN"
     CDS             5546..6415
                     /locus_tag="ctg1_527"
                     /transl_table=11
                     /translation="MEEQKNTYENVTLEPDVGFDIRFVTMDHNSPFHWHREMEILYILN
                     GHATVHMEGEEYELNPLDAVVMDYARIHEVIYALPQTMGICIHVSRQLLRRYLPEAEPF
                     AIRCAGQRLRPGQQEYYNEICGYLKELTVLYVNQNETYRLKSTARILELLACLVEHFSE
                     PVSMVATQTRAGKMERLEQICMYVDHHYREEMTLQEAADELGLNREYFCRFFKQSTGSS
                     FMRYVNQVRLNYIYQDLLHTDDPVQEIMERHGFFNQKLFYRMFKERYHCTPRQARRMAE
                     NNPYVEAK"
     CDS             complement(6932..8269)
                     /locus_tag="ctg1_528"
                     /transl_table=11
                     /translation="MTIPEEGEISMQFVKTADLKPGMRLAKPIYNRMGVLLYERDTRLT
                     IQGINSIENFGLIGIFILEPAEPLPPLSREDLEFEQFQTIYMFKLKDNMDKLVDNLVPS
                     TLLSLVDDIQRHYGSLDHKLNFTQTLRSSADFVYKHSISVGILSAMISNEMQLPAEDIR
                     ALITASLLYDFGYLYVPQAILDKGDDLSDSDQNFIQMNLERGYESIRPRYEECNLPKIS
                     LEIIQQFIFQKSQTLKIKDPSPETRLLCDILKVADQFDRLTAMNINNPPVSEVAAMSFL
                     RRHSRTYNPRVVAALAECIHILPTGACVDLSDGEKALVLVENAADFTRPMILKFSNNMI
                     YDLSDPVIGDSLRVTDIMKTMDNRIAIDEEALEHFVADQYIRETADRFRQKKLAIAQRK
                     QKAAQKKSMDDLLDNARVLTPPPIAPVPEEDASPIRKAPRKRMKLV"
     CDS             8394..9548
                     /locus_tag="ctg1_529"
                     /transl_table=11
                     /translation="MIQIPWRRVAGAALVMCLLLANTSYAETTQDNINDAKNQIEDLKD
                     QKKDAEDTVNDISGKKDALESDLSGLNGQLSDIVAQINDLEGQISDKQGEIDQAKEDLA
                     AAEAQSAKQYEDMKLRIQFMYENGSTPVWQMLAEAESFSDFLNRTEYITDINAYDRKKL
                     VEYQDLQEQIAAQKEDLESDMTELVAMQDDMKKKQANVSSLINTTKANLAQTQEDLADA
                     QSNVADLEDKINQMVEYEKQLEIQKAKEDAARLAAIKEQEKEDTSTVVYVPTDSDQYLL
                     GAIIQCEAGGESYDGKLAVGSVVINRVKSSYFPNSVSGVIYQSGQFSPVASGRLAYRLE
                     AGVDGSCLQAAQDVLNGNITVGCLYFRQNNGIIQGTVIGNHVFY"
     CDS             10001..11185
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_530"
                     /sec_met_domain="Thiolase_N (E-value: 4.2e-96, bitscore:
                     318.8, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 1.3e-49, bitscore:
                     164.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKVVLAGACRTAIGKMGGALSNTPAAELGSIVIKEALNRAGVK
                     PEQVDEVLMGCVIQAAQGQNVARQASIKAGLPIEVPAVTLNVVCGSGLKCVNEAATMIL
                     AGQADIVVAGGMENMSMAPYAMTKARFGYRMNNATIIDTMVNDALTDAFNHYHMMITAE
                     NVCEKYGLTREELDEFSANSQQKCEKAIAEGKFDDEIVPVPVKVKKETVMFAKDEGPRP
                     GTTAESLSKLKCCSGKEGGLVTAGNASGINDGAAAIVVMSEEKAKELGVKPMATWVAGA
                     LGGVEPEIMGVGPVASTRKVLERTGLTIDDMDLIEANEAFAAQSVAVARDLKFDMSKVN
                     VNGGAIALGHPVGASGCRILVTLLHEMQKRDAKRGLATLCIGGGMGCSTIVERD"
     CDS             11337..12209
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_531"
                     /sec_met_domain="HCDH (E-value: 5.4e-33, bitscore: 111.1,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 3e-59, bitscore: 197.5,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGVIGAGTMGQGIAKAFAQVDGYEVALCDIKQEWADGGKEKIK
                     KGYARLVEKGKMTQEAVDGILAKITPGLKEDLCKDCDLIVEAAFEDMGVKKTTFQELDK
                     IAKPECIFASNTSSLSITEIGNGLTRPMVGMHFFNPADRMKLIEVIAGVNTPEETVEAI
                     KKISVEIGKTPVQVNEAAGFVVNRILIPMINEAAFIKMEGVSDIAGIDAAMKLGANHPM
                     GPLELGDFIGLDICLAIMDVLYKETGDSKYRACPLIRKMVRGGNLGAKSGKGFYVYNAD
                     RTKTPVDAQ"
     CDS             12241..13395
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_532"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.5e-50, bitscore:
                     168.9, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 6.2e-29, bitscore:
                     97.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.2e-38, bitscore:
                     129.0, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTLDKKHEMARSLFREFAENEVKPLAQEVDETEEFPVENVKKM
                     QKLGFMGIPVPKEYGGQGCDPLTYVMCVEELSKVCATTGVIVSAHTSLCIDPIMTYGTE
                     DQKQKYVKPLATGEKLGAFALTEPGAGTDAQGAQTKAVLDGDEWVLNGSKCFITNGKVA
                     DVYIVIAITSVTEDKRGRKKKNFSAFIVDKGAPGFSFGTKEKKMGIRGSSTYELIFEDC
                     RIPKENLLGVEGKGFPIAMHTLDGGRIGIAAQALGIAEGALDRAIAYTKERKQFGRTIA
                     QQQNTQFKLADMAARIEAAQLLVYKAAMAKATQKVYSVEAAKAKLFAAETAMAVTTEVV
                     QLFGGYGYIREYDVERMMRDAKITEIYEGTSEVQRMVISGALLK"
     CDS             13441..14223
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 158.7;
                     E-value: 4.7e-49)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_533"
                     /sec_met_domain="ETF (E-value: 2.4e-47, bitscore: 158.7,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVVCIKQVPDTKGGVKFNPDGTLDRAAMLTIMNPDDKAGLEAA
                     LRLKEQYGAEVTVLTMGLPKADEVLREAMAMGADKGILVTDRVLGGADTWATSTTIAGA
                     LRNLDYDLIITGRQAIDGDTAQVGPQIAEHLGLPVISYAQDIKIDGEYVVVQRQYEDRY
                     HELKAKMPCLITALSELNQPRYMTPGGIFDAYDKEVTVWGRADLKDVDDSDLGLKGSPT
                     KIAKASDKVRKGAGEKVVLDPDESVAYLIGKFKEKHII"
     CDS             14251..15291
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 163.5;
                     E-value: 1.6e-50)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_534"
                     /sec_met_domain="ETF (E-value: 8.5e-49, bitscore: 163.5,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 2.2e-36, bitscore:
                     121.4, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLEEYKGVFVFAQQVDNVLDGVAFELLGKGKELAKDLNTEVTAV
                     LIGSGVKELADQLAEYGADRVIVVDDPQLKDYRTEPYAHALASVINEYKPEIMLVGATA
                     IGRDLGPTVSARVKTGLTADCTMLEIGDFPLNAAAGQEQQHNQLLMTRPAFGGNTIATI
                     ACPYNRPQMATVRPGVMQKIAPIAGAKANVVEYNPGFTPNDRYVEILNIVKAVKNTANI
                     MDAKILVSGGRGVGSKENFKLLEDLAEVLGGTVSCSRAVVENGWLPVDLQVGQTGKTVR
                     PQIYFAIGISGAIQHVAGMEDSDLIVAINKDEDAPIFDVADYGLVGDLNKIVPALTTAL
                     KAELGK"
     CDS             15432..16796
                     /locus_tag="ctg1_535"
                     /transl_table=11
                     /translation="VRQTVTENRLFSKKDLRKLIIPLILEQTLAITVGMADTMMISSAG
                     EAAVSGVSLVDMFNNLIISVLAALATGGAVVTSQCIGAGRREEACRSARQLVFTEAAIT
                     IGISVLVLLFHRQILGLFFGQIEADVMQNAIIYLIISVFSFPLLAVYDSCAALYRSMGN
                     AQITLKISLLMNVINVVGNAIGVYVLKLGVAGVAIPSLVSRGVAGVVLFTLLHNPDNLV
                     FLTRGKFKVDATIVKRILFIGIPSGIENGIFQLGRVLVVSIIAAFGTSQIAANGVANSL
                     DSMGCIVGQAMSLAMITVIGRCVGAGEEGQVRYYTKKLLGETYFYTAVINSIILLLLPW
                     ILQIYGLGEETTRLSYILVMIHDGMAIFLWPASFVLPNMLRACNDVKYTMVVSIFSMIT
                     FRIGFSYVFGVHMGWMAVGVWAAMVIDWVFRVLCFVGRYLAGTWRKKCGLVAPTA"
     CDS             16891..17481
                     /locus_tag="ctg1_536"
                     /transl_table=11
                     /translation="MTKSKFSTKYLVEMALLVAIILLMAFTPIGYIKTAGLEITLIVIP
                     VAVGAVTLGPAAGAILGGVFGITSFIQCFGMSAFGTLLLGVNPVFTFLVCVPTRILDGW
                     LTGLIYKGLKKTKIPSAGSVTLASLCCPLLNTTFFMGTLVTLFAGTMREQFGMTKVIPF
                     IAAFVGVNGVVEAIVCFVIGTAVSMALKKALRY"
     CDS             18175..19257
                     /locus_tag="ctg1_537"
                     /transl_table=11
                     /translation="MDYDTVRLDDENNAVVIIDQTKLPGKIEIISLHTAQEIWNAIYLL
                     QVRGAPAIGVAAAYGIYVLAKRMDTEDYDIFYREFVRQKEYLDSSRPTAVNLSWALNRM
                     QRVVEAHSGETVAQIKEALHRESVAIQEEDIWVCRMIGEHGLTLVKPGDGILTHCNAGQ
                     LATSKYGTATAPIYLGEERGYHFHVFADETRPLLQGARLTAFELQSSGVDVTLICDNMS
                     ATVMKNGWVNAVFVGCDRVAANGDAANKIGTSVVAAVAKYYGVPVYICAPTSTIDLNTP
                     TGAGITIEQRPAEEVTEMWYKERMAPEGVKVFNPAFDVTDHELIAGIVTEYGVARAPYT
                     ESLVAIFAEKEKRAREKKEA"
     CDS             19293..20147
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_538"
                     /sec_met_domain="CbiA (E-value: 1.5e-13, bitscore: 48.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPENSNCSGASSCSKESCEGCPSNAKNKAGGGIAKEPMNAASNVK
                     KVIGVVSGKGGVGKSFVTASLAAAMNRAGYKVGIMDADITGPSIPKMFGIHGQVYGTDD
                     GMVPMETENGIKIMSINLLLDDEEAPVIWRGPVIAGVVKQFWNETVWGDVDYLFVDMPP
                     GTGDVPLTVFQSLPVDGIVIVTSPQELVQMIVKKAYNMAEMMHVPVLGLVENFSYLKCP
                     DCGKEIKLFGESHIDDVAKELGIPVFGKLPLDPAFAEQADKGAFATMENAYLDAGVEKL
                     KTL"
     CDS             20264..20731
                     /locus_tag="ctg1_539"
                     /transl_table=11
                     /translation="MKIKIEIDESAAEDEVIIRCRGLTKQVAAVQRAVRDVTNASEKIL
                     LYKGNTEYYVTLSKILFFETDENGISAHTRDEMYQTRYKLYELEDMLPGVFMRVSKSTI
                     LNTDQIYSIDRNLTASSVVAFLNTHKKVYVSRYYYKPLTQKLEEKRLHHEK"
     CDS             20721..21413
                     /locus_tag="ctg1_540"
                     /transl_table=11
                     /translation="MKSSKVFWGIFFILAAVYVVISKFGILPDIGVFSIILTVFFLWLF
                     VEGIRNVNFWEILFSIAFICIIYDKPLGITALTPWTVLGAAFLGSIGLSLIFGGKKRKW
                     KTVTGNVGTSSSEQYTGEEIRCENSFGSAIRYINSDNFRRAAIENNFGSLSVYFDNAIV
                     QEGSANVSVENNFGETNLYIPKEWKIQNNLDRSFGAIRETGSSIGTSSTVLYLNGSANF
                     GEIHLHYI"
     CDS             complement(21993..23399)
                     /locus_tag="ctg1_541"
                     /transl_table=11
                     /translation="MNEKDGAIRDASVLGVPKMLILGLQHMFAMFGATILVPILVNSYF
                     GEDVLHVQVTLICAGIGTLFFHLCSKFKVPAFLGSSFAFLGGFATIANMDSGVFADMSN
                     ADKLSYACGGIVVAGLLYLILALIIKLVGVKKVMRFLPPVVTGPIIICIGLSLAGSAIN
                     NASTNWLLALIALVTIIIFNIWGRGMFKIIPILMGIIISYIAALIFNAMGMTNADGSAI
                     LSFTDIANASWVGVPAFSLCKFNLSAILVMAPIALATMMEHIGDISAISATVDQNFIED
                     PGLHRTLIGDGLATSLSALVGGPANTTYGENTGVLELSKVYDPKVIRIAACYAIILSFI
                     PKMAAVIGSMPSAIIGGVSFMLYGMISAIGVRNVVENHVDFTQSRNLIIAGVIFVCGLG
                     FSDGLTFTIAGTSVTLTALAVAAIAGIFLNAILPGNDYHFGKDITGDANRGIDMKPNLH
                     EDTSYTDTEE"
     CDS             complement(23482..24255)
                     /locus_tag="ctg1_542"
                     /transl_table=11
                     /translation="MSRSSSELKRISRDILNNRYSVPMAAFLTASLIPTLIEIPFSMTL
                     GDYPGTPQLIISTIADILILLIAQMLETGVMLVHMNMTRGQTYRIRDVFTPFRNGAERF
                     FLAAVLFDVFLVIAGIPAIAGVLYFYKTGVSGLSGALLAAGSILGLIFTFCVLLTYRMV
                     FFFLLDHPHLSVRDAFRTCRKFMRGRRRKLLYILFSFLGWGALAICSFGIAALWISPYM
                     TQTLLTFYLDGTGELDQIPVRDYDQEARRFTGSIF"
     CDS             24678..25121
                     /locus_tag="ctg1_543"
                     /transl_table=11
                     /translation="MEIGMFQTDRRVDRDFYIMGWCAAGIFAALFLFVRVTGIPVWKFL
                     LPCPFHALTGAYCPGCGGTRAVRALLAGKWLRSFVLHPFVPYAALLSGWFMISQTIERV
                     SGSRIRIALRFRDVYIWIALLLIVVNCLVKNLALFVWHVDLLA"
ORIGIN
        1 taatgcttgg aatttatgga acctcgtata cggggcaagt gatatataat ggctacagac
       61 tgggtgaatt ggattataag tggtttatta acaacaatac ggctgttata gagcaggatc
      121 cctatatatt tgatggaaca attcaagaga atatatgttt gaaggggaat cggatagata
      181 tggatgaatt gaaagcatta gtgagccaaa tgaaattgga ttcgctgatg aagtttgtag
      241 atatggatag tacaaagcat agagagaata agatatattc agggggagaa aagcaaaaga
      301 tagcaattgt cagaacattg ttatcggatt catgcatatg gattttagat gaaccgacag
      361 caaaccttga tgaagaaagt aaaattatct tctataagga gttagagcaa cgaaaaaagg
      421 aacacattat attgctgatt tcgcatgaaa cgccattgtg tcggtgggat catattgttg
      481 atataggacg atgaacgtcc aatttgtcca taatgtataa tttttataca tcacagtgta
      541 aaaattatac attatttggt tccggaaaaa ggttgaaaaa tatcctgtga tatgataaac
      601 tttttacaat ttaggaaaaa ggcatagcac tgcccataat ggcacgaaga cgatgcatca
      661 cacaccgtgt gcatgtgcgt tctggaaaaa agaagaaaaa cggaaacgtt tttttttttg
      721 ggaaaaaagt gaaaggacag ggagacgaat gaaagctttt ttgatactcg aagatgggaa
      781 tgtatttaca ggaaccagca ttggttccac cagagaggtc atcagtgaga tcgtgtttaa
      841 cacatcgatg accggttatc tggaggttct gaccgatccg tcctatgcgg gacaggcagt
      901 tgtgatgacc tatccgctga ttggaaatta cggaatcacg ccggatatgg agtcgggacg
      961 gccgtggccg gacggttata tcgtgaggga actgtccaga atgccgagca atttccggtg
     1021 cgaggggacg attcaggatt ttctcgcaaa atacgatatt ccgggaattg ccggaattga
     1081 tacgcgtgcg cttaccaaga tccttcgtga gaagggaacg atgaacggta tgatcacgac
     1141 gaatgagaac tataatatag aagaaatcat tcctaaatta aaagcataca cgacaggcaa
     1201 cgtggtagat aaagttacct gtacggaaaa acgagtatta aaaaagcagg gaaatgcccc
     1261 tgagacgaaa aaagtggcgc ttcttgacct tggagcaaag cgcaatattg tccagtcctt
     1321 acgagagaga ggctgtgagg tgacggtata cccggcacat acttctgcgg aggagattct
     1381 ggcggcgaac ccggacggca ttatgttaag caacggaccg ggagacccga aagagtgcaa
     1441 ggagatcatt gcagagatcc gcaagctgta tgaatccgat acgccgattt ttgcaatctg
     1501 cctgggacat cagctcatgg cgcttgcaac gggggctgac acgcacaaga tgaagtacgg
     1561 acaccgcgga ggcaatcatc cggtcaagga tctggcgacg aaccgcgtct acatttcttc
     1621 acagaatcac ggctatgtgg tagacaccga tactctggat ccgaaggtgg cgacaccagc
     1681 atttgtcaat gtcaacgacg gaacgaacga gggactttcc tatgtcggca agaacatttt
     1741 cacggtgcag ttccatccgg aagcgtgtcc gggaccgcag gattctgcat atctgtttga
     1801 cagatttata aacatgatgg gaggagcgaa ataatgccaa gaaatcagga gattaagaag
     1861 gtacttgtaa tcggttccgg tccgattgtc atcggacagg cggcggagtt cgactatgca
     1921 ggaacacagg catgccgttc cctgaaggaa gagggcgtgg aagttgttct ggtcaattcc
     1981 aacccggcga ctatcatgac ggataaagac attgcagatc aggtctacat cgagccgctc
     2041 accgtgccgg tgttagagca gatcattgca aaggaaaagc cggattccat ccttccgacc
     2101 cttggcggac aggccggatt aaatctcggc atggagcttt ccgagaaagg aattctggat
     2161 aagtacggcg tgaagctgat cggtacgacc gcagagacca ttttcaaagc ggaagaccgc
     2221 caggcattca aagacacgat ggagaagatc ggagagcctt gtgcggcatc cgaggtcgtg
     2281 cacaatgtgc aggatggtat taagttcaca aacaccatcg gctatccggt tgtgctccgc
     2341 ccggcgtaca cgcttggcgg aagcggcggc ggtattgcac acgatgagac cgagctgatc
     2401 gagatcctga caaacggact ccgtttaagc cgtgtcggag aggtgctcgt ggagcgctgc
     2461 atcgcaggct ggaaagagat cgagtatgag gtaatgcgtg atgcgaatgg caactgcatc
     2521 acggtatgta acatggagaa cattgatccg gtcggcgtgc ataccggcga ttccatcgta
     2581 gtcgcaccgt cacagacgct gggcgacaag gaatatcaga tgctccgtac ctctgcttta
     2641 aatattatat ctgaattaaa tatcacgggc ggatgtaacg tgcagtatgc actcaatccg
     2701 gagagctttg agtattgcgt catcgaggta aacccgcgtg tgtcccgttc ctccgcgctt
     2761 gcatccaagg cgaccggtta tccgattgca aaagttgctg caaagatcgc gcttggctat
     2821 acgcttgacg agatcaagaa cgccatcacc ggaaaaacct acgcaagctt tgagccgatg
     2881 cttgactact gcgttgtcaa gattccgaga ctgccgttcg ataaattcat taccgcaaaa
     2941 cgtacactga ccacacagat gaaggcaacc ggagaggtta tgagtatctg caataacttc
     3001 gagggagcct tgatgaaggc gatccgttcc ttagagcagc atgtggacag cctgatgtcc
     3061 tatgatttta ccggactttc cagagaggaa ctggtaaaac agcttcacgt tgtggatgac
     3121 cggagaatct gggtgatcgc agaggcactg cgccgcggta tggattacga tgtgattcac
     3181 gacatcacca agattgataa gtggttcatc gataagctgg caatcctggt tgagatggag
     3241 cagaagttaa agagcgagcc gcttacggta gaactgttaa aagaggcaaa acgaatcgag
     3301 ttcccggata aggtgatcgc agaactgacc ggaaagaccg agacagagat ccatgatatg
     3361 cgctacgcaa acggtattgt ggcagcatac aagatggtag atacctgtgc ggcggagttc
     3421 gaggcgacca caccgtacta ctattccgta ttcggcagcg agaatgaggc ggaagagacg
     3481 cacccgaaca agaaggtgct ggtacttggt tccggaccga tccgtatcgg acagggaatt
     3541 gagtttgatt actgctctgt acattgtacc tgggcattcg caaaagaagg ctgggagacc
     3601 gtcatcgtca acaacaaccc ggagaccgta tcaacagact ttgatattgc ggataagctg
     3661 tactttgagc cattgacgcc ggaggatgtg gaagccatcg taaaacttga gaagccggac
     3721 ggtgcggtgg tgcagtttgg tggacagact gcgatcaagc tgacggagag cctgatgaag
     3781 atgggtgtga agatcctcgg aaccaaggcg gaggacgtcg acgctgcgga ggatcgtgag
     3841 cttttcgatg agattctcga gaagaccaaa attccgagag cagcaggcgg aacggtattt
     3901 accgcggagg aagcgaagga agtggcgaac cgtctgggct atccggtgct tgtgcgcccg
     3961 tcctatgtac tcggcggaca gggcatgaag attgcattta acgatgacga gatcgaggaa
     4021 ttcatcggca tcatcaaccg gattgcacag gatcacccga tccttgttga taaatatctg
     4081 cagggcaagg agatcgaggt cgacgctgtg tgtgatggaa cggacatcct gattccgggt
     4141 atcatggagc atatcgagag aaccggtgtc cattcgggag acagtatttc cgtctatccg
     4201 gcaccgacga tcagcgatca tgtaaaagag acgatcgtgg aatatacgaa gcgcctggca
     4261 caggcactgc atgtcatcgg actgatcaac atccagttta tcgcgatgaa tgaagaggtc
     4321 tatgttatcg aggtaaaccc gagatcttca agaaccgtgc cgtacatcag caaggtgacc
     4381 ggtattccga ttgtcgatct cgcaacgaag gtcattatcg gaaacacaat ccgcggactt
     4441 ggctatgagc cgggacttgc accgacggct gattacattg ccatcaagat gccggtattc
     4501 tcgtttgaga agctgcgcgg agcggagatt tcccttggac cggagatgaa gtccacaggt
     4561 gagtgccttg gtattgcaaa gacattcaac gaggcattat ataaggcttt ccttggtgcc
     4621 ggtgtgacac tgccaaaata taagcagatg attatgacgg taaaggatgc ggacaagccg
     4681 gaggccgttg gcgttgcaaa gcgttttgaa gcgctcggct acaagattta cgcgaccaga
     4741 agcaccgcga aatatttgca ggagcatggg gtgaatgcgc tgcgtgtcaa taagattaca
     4801 caggaatccc cgaatgtcat ggatctgatc cttggtcata agattgatct tgtgatcgat
     4861 actccgacac agggcaatgg agacaagacg cgcgacggct ttttgatccg ccgaaatgcg
     4921 atcgagaccg gcgtgtactg tatcacagcg atggatacgg caaacgcact tgcaagaagc
     4981 cttgagacag cgatggatac gctgactccg gttgatattg cgaaagtgaa gaatttataa
     5041 acaaaaaaaa gaatctcgct tgcgagattc tccgcgcgcg agcggttcgc aaagcgatat
     5101 tttccatacc gcgagctgcg catccgcgcg gagcgattct tatttcatag gaaggaccta
     5161 ctttcgtaca ttaatgtgtc aaggtatttc ttatgaaata agaaagagcc tgtatacgga
     5221 tggatgagaa ctcatcgcac cgttacaggc tcttttttgg taaaattttc tgttgtcatg
     5281 gcgttgctcc gggattagtt gtaatatgga tgaatgtcaa ctccgtacat tgcttcaaca
     5341 cccattgcga ctccgtcgat attctccatg aagaatgctt tgatttttgc taacataata
     5401 atttcctcct ttattgaatt ggtacatttt tgcttgttca tcaaaggttt tccctttgac
     5461 agctattata atacacggaa atatggtaat attatagata agatattagc aaaaagttgg
     5521 gtgatattga cttttaggag aaaaaatgga agaacagaaa aatacatatg aaaatgttac
     5581 gctcgaaccg gacgtcggct ttgatatccg gtttgttacg atggatcata actctccgtt
     5641 tcactggcac cgggagatgg agattctcta catattaaac gggcatgcca ctgtgcatat
     5701 ggagggtgag gaatacgaac tgaatccgtt ggacgcggtt gtgatggact atgccagaat
     5761 tcatgaagtc atctatgcgc tgccgcagac aatgggaatc tgtatccacg tgtcaaggca
     5821 gcttctgcgg cgctatctgc cggaggcgga accttttgcg atccgctgcg cgggacagcg
     5881 tctccgtcca gggcagcagg aatattacaa tgaaatctgc gggtatttaa aagaactgac
     5941 ggtgctttat gtgaatcaga atgagacgta ccggttaaaa agcacggcgc ggattctgga
     6001 attgctggca tgtctggtgg aacatttttc ggaacctgtc tccatggtgg caacgcagac
     6061 gagggcgggg aagatggagc ggctggagca gatctgtatg tatgtggatc atcactacag
     6121 ggaagaaatg acgctgcagg aagcggcgga tgaactgggg ctcaaccggg aatacttctg
     6181 ccggttcttt aagcagagca ccggcagctc gtttatgcgc tatgtaaatc aggtgcggct
     6241 caattatatc tatcaggatc tgctgcacac ggacgatccg gtacaggaga tcatggagcg
     6301 gcatggcttc tttaatcaga agctttttta ccggatgttc aaggagcgtt accactgtac
     6361 tccgcgccag gcgcgccgga tggcggaaaa caatccttat gtggaagcaa aataaccgcg
     6421 ctgtatatgc aggggggagg atataagttc cggatgcagc ccggtgtgaa gcatccttga
     6481 agcaaaatac gagcatttct tccacgtcgt gtttgacatt ttattctgtg tctttgccac
     6541 gttttgacaa tccacaggat gtgtccgaca ggttgcagac aatgggcgga cttcctggtg
     6601 tccctaatgt catcgcttca cagacaatat aaaaccgcgc gaaccgaaac tcgcaggcat
     6661 ctgctattga agacacggca gatacctgct cagacatcgg cttcgcgcgg ttatgttttg
     6721 ttcagcgatg acagtaaggg acacacacga aagtcctaaa attgtctgca acctgcggac
     6781 acacctcgtg gagtgctcaa aacttggaaa gacacggatc atcgagaatg tcaaacacga
     6841 tgcggctaga aatgccggat ttggcggtta gaatgcttca caccgggctg catccggaac
     6901 gatacgccgt tcccaccctt cacataaaat attaaaccag tttcatgcgc ttgcggggag
     6961 ctttcctgat cggggaagcg tcctcttccg gcactggtgc gatgggcgga ggtgtaagca
     7021 ctctggcatt gtccaaaaga tcatccatgc tcttcttctg ggcagctttc tgcttgcgct
     7081 gtgcgatggc aagctttttc tgccggaaac ggtcagccgt ctcacggatg tactggtctg
     7141 cgacaaaatg ctcgagcgcc tcctcgtcga tcgcaatccg gttgtccatg gttttcatga
     7201 tgtccgtcac acgcagggaa tctccgatga ccggatcact cagatcgtag atcatattgt
     7261 tggagaactt taagatcatc gggcgggtaa aatccgcggc attttccacg aggacgagcg
     7321 ccttctcacc gtcggagaga tcaacgcacg cgccggtcgg gagaatgtgg atgcattccg
     7381 ccagtgcggc aacgacgcgc ggattgtagg tccggctgtg tctgcgcaaa aaagacatcg
     7441 cggcaacctc cgagaccggc ggattgttaa tattcatggc ggtaagccgg tcaaactgat
     7501 ctgccacctt taaaatatca cagagcagac gtgtctccgg ggaaggatcc ttgatcttta
     7561 aggtctgact cttctggaag atgaactgct ggataatctc taaggaaatc ttcggaagat
     7621 tgcactcctc atagcgcggg cggattgatt cataaccgcg ttccagattc atctggataa
     7681 aattctggtc gctgtccgag aggtcgtcgc ccttgtcgag gatggcctgc ggaacataca
     7741 gataaccgaa atcatacagc agggaagccg tgatcagcgc ccggatatct tctgccggga
     7801 gctgcatctc attggagatc attgcggata ggataccgac actgatcgag tgtttgtata
     7861 caaagtccgc ggaactgcgg agtgtctgcg taaaattcag cttgtggtca agactgccgt
     7921 aatgccgctg gatatcatcg accagcgaga gcagtgtgga cgggacaaga ttgtcgacaa
     7981 gcttgtccat gttgtccttt aacttgaaca tgtagatggt ctggaactgt tcaaactcca
     8041 gatcttcccg cgaaagcggc ggcagcggtt cagccggctc cagaataaaa atgccgatca
     8101 gaccaaaatt ctcaatactg ttaataccct ggatcgtgag ccttgtatcc cgttcgtata
     8161 acagaacccc catcctgttg tagattggct ttgcaaggcg cataccgggc tttagatcag
     8221 cagttttgac aaattgcatg cttatctccc cctcttccgg tattgtcata ccaaaatcct
     8281 ctttatcttc cctctatgat agcatattga aagctgaaat acaatctgat atgatactct
     8341 tagaaccggg gtttttgaaa gaaaatccta cttttccgga gaaagaggta cttatgatac
     8401 agattccgtg gagacgcgtg gcgggagcag cgctggtaat gtgcctgctt ctggcaaata
     8461 catcttatgc cgagacgaca caggacaaca taaatgatgc gaagaatcag attgaggatc
     8521 tgaaagatca gaaaaaggat gccgaggata ccgtcaatga catctccggc aaaaaggatg
     8581 cactggagtc ggatcttagc gggttaaacg gtcagctttc cgatattgtc gcacagatca
     8641 atgatctgga ggggcagatt tcggacaaac agggggagat tgaccaggcg aaggaggatc
     8701 tggctgcggc ggaggcacag tctgcgaaac agtatgagga tatgaagctg cggattcagt
     8761 tcatgtatga gaacggaagc acgccggtat ggcagatgct tgcggaggcg gaatcttttt
     8821 ccgacttcct gaaccgcacg gaatatatta ccgacatcaa cgcctacgac agaaaaaagc
     8881 ttgtggaata ccaggatctg caggagcaga tagccgccca gaaggaagat ctggagagtg
     8941 atatgaccga gctggtggcg atgcaggatg acatgaagaa aaagcaggcg aacgtcagca
     9001 gtctcatcaa caccaccaag gcgaatctgg cgcagacaca ggaagatctg gcggatgcgc
     9061 agtccaacgt cgcggacctg gaggataaga tcaaccagat ggtcgagtac gagaagcagc
     9121 tggagatcca gaaggcgaag gaggacgctg cgcgtctggc ggcgattaag gagcaggaga
     9181 aggaggatac ctccaccgtg gtctatgtgc cgacggacag tgaccagtac ctgcttggag
     9241 caatcatcca gtgcgaggcg ggcggagaat cctacgacgg gaagcttgcg gtcggaagcg
     9301 ttgtgataaa ccgtgtgaag agttcgtatt ttccgaactc tgtctcgggt gtgatttacc
     9361 agagcggtca gttctcgccg gtggcgagcg gcagactggc gtatcgtctg gaagcgggtg
     9421 tggacggaag ctgccttcag gcggcacagg atgtgctaaa cggcaatatt acggtgggct
     9481 gcctgtattt cagacagaat aacggcatca tacagggaac cgtaattgga aaccatgtat
     9541 tctattagaa gtgaaaaaag tgcggaaaac cgcagaatgg cagcagggcg atttttgtga
     9601 aaagtacaca agaatcgctt tgcttttgtt tggaaaataa aatttgcatg ataaattttt
     9661 aacaaaaaaa agactgtaaa acagacgtat agagggggaa aaaggagcgt aaagaaaaca
     9721 ttagaaagat gaaaaaagaa gaaagttatt gcatttaaga gtgaaatatg gtagcatgaa
     9781 aaagtattaa aaagctagta aaaacgccga ttatttaaaa tgcaccttgt gaaaaaaaga
     9841 gggagaaaca taaattttaa ctgcaaagtt gaatttattt tttttagcaa aaagattgtt
     9901 aaaaaattaa cagcgttttt cggcaaaatt attttttaaa gaggaacaaa ttccccgtac
     9961 atacggggtt ttgtgtgtaa aactgaaagg agaattcaaa atggcaaaga aagtagtttt
    10021 agcaggcgca tgccgtaccg ctatcggcaa gatgggtgga gcactgagca atactccggc
    10081 agcggagctg ggatcaatcg taatcaaaga ggcattgaac agagctggcg taaagccgga
    10141 gcaggtagat gaagtattga tgggatgtgt tatccaggca gcacagggac agaacgttgc
    10201 acgtcaggct tccatcaagg caggacttcc gatcgaagta ccggcagtta ctctgaacgt
    10261 tgtatgtggt tccggactga aatgtgtcaa tgaagcagct actatgattc tggctggtca
    10321 ggcagatatc gttgttgcag gtggtatgga gaacatgtcc atggctcctt atgccatgac
    10381 gaaggctcgt tttggatatc gtatgaacaa tgcgaccatc attgatacca tggtaaacga
    10441 tgcactcacc gatgcattca accactatca catgatgatc acagctgaga acgtatgtga
    10501 gaagtatggt cttacaagag aagaactcga tgagttctcc gcaaacagcc agcagaagtg
    10561 cgagaaggca atcgctgagg gcaagttcga tgacgagatc gttccggttc cggttaaggt
    10621 taagaaagag accgttatgt tcgcaaaaga tgagggaccg cgtcctggca caacagctga
    10681 gtcactgtcc aagttaaaat gttgctccgg caaagagggc ggactggtaa ccgcaggtaa
    10741 cgcttccggt attaacgatg gtgcagctgc aatcgttgtt atgagcgagg agaaggcaaa
    10801 agagcttggc gttaagccga tggcaacatg ggtagccgga gcactcggcg gagtagagcc
    10861 tgagatcatg ggtgtcggac ctgttgcatc taccagaaag gtacttgaga gaacaggact
    10921 taccatcgat gatatggatc tgatcgaggc aaacgaggca ttcgcagcac agtctgttgc
    10981 agttgcaaga gatctgaagt ttgatatgtc caaggtaaac gtaaacggcg gtgcaatcgc
    11041 acttggtcac ccggtaggag cttccggatg ccgtatcctt gttaccttat tacatgagat
    11101 gcagaagaga gacgcaaaga gaggtcttgc tactctgtgc atcggtggtg gtatgggatg
    11161 ctctaccatc gttgagagag actaatgcag ttatgagaac ttctgaaccg gcgccagcct
    11221 gtgggcggca ccggagaagt tcttgctttg cgtaatagga atctttgttc ctattttatt
    11281 aaaaggcata gaatcagtta ttagaatata tatatgatat ttcaggaggt acagacatga
    11341 aagttggagt tattggtgca ggaacaatgg gacagggtat tgcaaaagca tttgcccagg
    11401 tagacggata tgaagtagca ctctgcgaca tcaagcagga gtgggctgac ggcggaaaag
    11461 agaagatcaa gaaaggctat gcaagacttg tcgagaaagg aaaaatgaca caggaagcag
    11521 tagacggcat tctcgcaaag attaccccag gtttaaagga agacctttgc aaggattgtg
    11581 acctcatcgt agaggcggct ttcgaggata tgggcgttaa gaagactaca ttccaggagc
    11641 tggataagat tgcaaagcca gagtgcattt ttgcatccaa cacatccagc ctttccatca
    11701 cagagatcgg caacggactg acccgtccaa tggtaggtat gcatttcttc aacccggcag
    11761 accgtatgaa gttaatcgag gttatcgcag gtgtgaatac accggaagag accgttgagg
    11821 cgatcaagaa gatttccgta gagatcggca agactccggt acaggtaaat gaggcagcag
    11881 gcttcgttgt aaaccgtatt ttaatcccga tgatcaatga ggcagctttc attaagatgg
    11941 aaggtgtatc tgatatcgca ggtatcgatg cagcaatgaa actcggcgca aatcatccga
    12001 tgggaccgct tgagttaggt gattttattg gtctggatat ctgccttgca atcatggatg
    12061 ttctctacaa agagacaggc gacagcaagt accgcgcatg cccgttaatc cgcaagatgg
    12121 ttcgcggcgg caatcttggc gcaaagagcg gcaagggatt ctatgtatac aatgctgacc
    12181 gtacaaagac cccggttgat gctcagtaaa atataaggta ataatggagg aaatgatatc
    12241 atggatttca ctttagacaa gaaacatgaa atggcgcgct ccctgttcag agagttcgct
    12301 gagaacgagg taaagcctct cgctcaggaa gtagatgaga cagaggaatt cccggttgag
    12361 aacgtgaaga agatgcagaa gctcggcttc atgggcatcc cggtaccgaa ggagtacggc
    12421 ggacagggct gtgacccgct cacctatgta atgtgcgtag aggagctgtc caaggtatgc
    12481 gctacaacag gtgttattgt ttctgcacat acttctctct gcattgatcc gattatgacc
    12541 tacggtacag aggatcagaa gcagaaatac gttaagccgc ttgcaacagg cgagaagctc
    12601 ggtgcattcg cactgactga gccgggtgca ggaaccgatg cgcagggcgc acagaccaag
    12661 gctgtattag acggagacga gtgggtatta aacggctcca agtgcttcat cacaaatggt
    12721 aaggttgcag atgtttatat cgtaatcgca atcacaagcg taacagagga taagagaggc
    12781 agaaagaaga agaacttctc tgcatttatc gtagataagg gagctccggg cttctccttc
    12841 ggaaccaagg agaagaagat gggtatccgc ggatcatcta catacgagct gatcttcgag
    12901 gattgcagaa tcccgaagga gaacctgctt ggcgtagagg gcaagggatt cccgatcgct
    12961 atgcacacac tggatggcgg acgtatcggt attgctgctc aggcacttgg tatcgcagag
    13021 ggcgcattag accgcgcaat cgcatacacc aaggagagaa aacagttcgg ccgtacgatt
    13081 gcccagcagc agaatacaca gttcaagctg gctgacatgg ctgcaagaat tgaggctgca
    13141 cagcttcttg tatacaaagc tgctatggca aaggcaacac agaaggtata ttctgtagag
    13201 gctgcaaagg caaaactgtt cgcagcagag actgctatgg ctgttaccac agaggttgtc
    13261 cagctgtttg gtggatacgg ttacatcaga gagtacgatg tagagcgtat gatgcgtgac
    13321 gcaaagatca cagagatcta cgagggaacc agtgaggttc agagaatggt tatctctggt
    13381 gcattactga aatagtcgta atccgtggca taatataaaa atataaggag tgaaaaatac
    13441 atgaatatcg tagtatgtat taaacaggta ccagatacca agggcggcgt taagttcaac
    13501 ccggacggta cattagacag agctgcaatg cttaccatca tgaacccgga tgacaaagca
    13561 ggtcttgagg cagcacttag attaaaagag cagtacggcg cagaagtaac cgttcttacc
    13621 atgggtcttc cgaaggcaga cgaggtgctt cgtgaggcaa tggcaatggg cgcagacaaa
    13681 ggaatccttg taacagatcg tgtgttaggc ggagctgata catgggctac ctccaccaca
    13741 atcgcaggcg cactccgcaa tctggattac gatctgatca tcaccggacg tcaggcgatc
    13801 gatggtgata ccgctcaggt aggaccgcag atcgcagagc atctgggact tccggttatt
    13861 tcctacgcac aggacatcaa gatcgatgga gaatatgtcg ttgttcagcg tcagtacgag
    13921 gacagatacc atgagttaaa ggcaaagatg ccgtgcctga tcacagcact ttccgaactg
    13981 aatcagccgc gttacatgac tccgggcgga atcttcgacg catacgataa ggaagttacc
    14041 gtatggggaa gagcagatct taaggatgta gatgattctg atcttggatt aaagggatca
    14101 ccgacaaaga tcgcaaaggc atctgacaag gtacgtaagg gcgcaggcga gaaggttgtc
    14161 cttgatccgg atgagtccgt agcatacctg atcggcaagt tcaaagagaa gcacattatc
    14221 taacaaatat aaggaaaagt ggtgaataaa atgggtttag aagaatataa aggagtattt
    14281 gtctttgcac agcaggttga caacgtatta gacggcgttg ctttcgagtt acttggaaaa
    14341 ggaaaagagc tggcaaagga tttaaacaca gaagtaactg cagtattgat tggctccggc
    14401 gttaaggagc tggcagatca gcttgctgag tacggcgctg acagagtcat cgtggtagac
    14461 gatccgcagt taaaagacta cagaacagag ccgtacgcac atgcactggc atctgtgatc
    14521 aatgagtaca agccggagat catgctggtt ggcgcaactg caatcggccg tgacctcgga
    14581 cctactgttt ccgctcgtgt gaagacaggt cttactgctg actgtacgat gcttgagatc
    14641 ggcgatttcc cgctgaacgc agcagctgga caggagcagc agcacaatca gcttcttatg
    14701 acacgtcctg catttggtgg taacacgatc gcaacgatcg cgtgcccgta caaccgtccg
    14761 cagatggcta ctgtacgtcc gggtgttatg cagaagatcg ctccgatcgc aggcgctaag
    14821 gcaaatgtgg tagagtacaa tccgggattc accccgaatg acagatatgt agagatctta
    14881 aacattgtaa aggctgttaa gaatacagcg aacatcatgg atgcaaagat cctggtatcc
    14941 ggtggacgtg gtgttggttc caaggagaac ttcaagcttc tcgaggatct ggcagaggta
    15001 cttggcggta ccgtaagctg ctcccgtgcc gtagtggaga acggctggct gccggtagat
    15061 ttacaggtag gacagacagg taagacagta cgtccgcaga tctacttcgc aatcggtatt
    15121 tcaggagcta tccagcacgt tgcaggtatg gaggattctg atctcatcgt tgctatcaac
    15181 aaggatgagg atgcgccgat cttcgacgtt gcagattatg gtctggtagg agatctcaac
    15241 aagatcgttc cggcactgac cactgcgtta aaggcagaac ttggcaaata agcaaagaaa
    15301 agtacatagg tgaaaagaac tcccgcgtgg cagatgtggc gtctgtcatg cgggagtttt
    15361 tatgttttta tttcacgagc ttgacagttg ccgttttgcg tattattgtc attccgaagg
    15421 agtgaaagaa cgtgagacag acagtaacag aaaatcgatt attcagtaaa aaagatttgc
    15481 ggaaactgat tattccgctg atcttagaac agacgcttgc catcaccgtg ggaatggcag
    15541 atacgatgat gatttcttct gcgggagaag cggcagtttc cggcgtgtcg ctggtagaca
    15601 tgtttaacaa cttaatcatc agtgtgctgg cggcgcttgc gaccggcggt gcggtggtaa
    15661 cgtcacagtg tatcggtgcg ggaaggagag aggaagcctg tcggtctgcc agacagcttg
    15721 tgtttacaga ggcggcgatc acgatcggta tcagtgtact ggtacttctt tttcacaggc
    15781 agatcctcgg attattcttc ggacagattg aggcggatgt tatgcagaat gcgatcatct
    15841 atctcattat ctccgtgttc tcatttccgc ttctcgcagt gtatgactcg tgtgcggcgc
    15901 tgtaccgttc gatggggaat gcgcagatca cattgaaaat atcgctgctg atgaatgtca
    15961 tcaacgttgt gggaaatgca atcggcgtgt atgtgctgaa actgggagta gcgggagtcg
    16021 ccattccgtc gttggtttcc cgcggtgtgg caggagtggt gctttttacg cttttgcata
    16081 atccggacaa tctggtcttt ctcaccagag gaaaatttaa agtggacgca acgattgtga
    16141 agcggattct ttttatcggc atcccgagcg gaattgaaaa cggtatcttc cagctgggac
    16201 gtgtgcttgt ggtcagcatc atagctgcgt tcggcaccag ccagatcgcg gcgaacgggg
    16261 tggcgaacag tctggattcc atgggatgta ttgtgggaca ggcgatgagc cttgcgatga
    16321 ttactgtgat cggacgctgt gtgggagccg gagaagaagg acaggtgcgc tattacacca
    16381 aaaagctgct gggagagacc tatttttata cggcggtcat caacagcatc attttacttc
    16441 tgctgccgtg gattttacag atctatggac tgggagagga gacgacgcgc ctgtcctaca
    16501 ttctggtcat gattcatgat ggaatggcga tcttcctgtg gccggcgtcg tttgtgctgc
    16561 cgaatatgct ccgcgcctgc aacgatgtaa aatacacgat ggtcgtgtcg attttttcca
    16621 tgattacctt ccgtatcggc ttcagttatg tgtttggtgt tcacatggga tggatggcag
    16681 tcggggtgtg ggctgccatg gtaattgact gggtgttccg tgtactctgt tttgtgggaa
    16741 gatatctggc gggaacctgg cggaaaaaat gtggtcttgt ggcgccaacc gcttgataaa
    16801 tatttcacat agtgatatac tgcaaaagat gcaaaaagtt cctggcagac aggaaccata
    16861 aacaaagtat acagaaaaga ggaaaagact atgacgaagt cgaaattttc tacgaagtat
    16921 ctcgtggaga tggcgctttt ggttgccatc atcttactca tggcttttac cccgattggt
    16981 tacataaaga cagcaggtct tgagattacc ctgattgtca taccagttgc ggtaggagct
    17041 gtaacattgg gaccggcggc aggagcaatc ttaggcggtg tgttcggtat cacgagtttt
    17101 atccagtgtt ttggaatgag cgcgtttggt acgctccttc tgggcgtaaa cccggtattc
    17161 acatttctgg tatgtgtgcc gacacgtatt ctggacggat ggctgaccgg actgatctac
    17221 aagggactga agaagacgaa aataccttcc gcaggttcgg taacgcttgc cagcctttgc
    17281 tgtccgctgc tgaacaccac atttttcatg ggaacactgg taactctgtt cgcaggaaca
    17341 atgcgtgagc agttcggcat gacgaaagtg atcccgttta tcgcagcatt tgtcggcgtg
    17401 aacggcgttg tcgaggcgat cgtatgtttc gttatcggaa cagcggtttc catggcactg
    17461 aaaaaagcac tccgctacta ggaacaataa gtaatattac gagaagaaat acacttgggg
    17521 atttcatgtg gaaatgcagc tggaaattcg gttcaaaaaa tgtggatttc taaccagccg
    17581 aatgtttgca tctttgatga tccgtgtctt tccaagtttg gagtactccg cgggtcatgt
    17641 ccgcatcccg gaagacaatt tgtaggactt ttgtgtgtgt cccttatgac acctctgagc
    17701 aaaacataac cgcgcgaagc cgatgtctga gtcggcatct gccttatttt caatagcaga
    17761 tgccggcgag tttcggttcg cgcggtttta tactgtctgt gaagaggtgc cattagggac
    17821 accagaaagt ccgcccattg tctccggtgt gtcggacatg cacccgtcgg attttccaaa
    17881 cgtggaagag acacggaatc cgatgcaaac attcagcaga aagaaatgca cacatttttc
    17941 tccaacgaat ttccatttgt atttccatct gaaatcccac ggtgtggtct tctcatatta
    18001 ttacttatca cccaaacgat ctatgcttat tgcggcaatt ccttttttgt ccgcaaaaaa
    18061 gaacacgaga aggcgggcgt attcttggaa acatcgacaa aagagagtat aatagtctgt
    18121 gatgaataag aataaagggg tgaaagtgtg ggagaacagc agagcaggaa tattatggat
    18181 tatgacaccg tgcggctgga tgatgagaac aatgcagtgg tgatcatcga ccagacgaag
    18241 ctgccgggaa aaatagagat catttcgctt cacacggcgc aggaaatctg gaacgcgatc
    18301 tatctgcttc aggtgcgcgg agcaccggcg atcggagtgg cggcggcata tgggatctat
    18361 gtgctggcaa aacggatgga tacggaggat tacgatatat tttaccgtga gtttgtacgg
    18421 cagaaggagt atctggattc ttcgcgcccg acagccgtga acttaagctg ggcgttaaac
    18481 cggatgcagc gtgttgtgga ggcacacagt ggggagactg tagcgcagat caaggaggca
    18541 ctgcaccggg agtctgtggc gatccaggag gaagatatct gggtgtgccg gatgatcgga
    18601 gagcatggtc tgactctggt aaagccgggg gatggcattc tgacgcactg caatgcagga
    18661 cagctcgcca cgagtaaata tggcaccgcg acggcgccga tctatctggg agaggaacga
    18721 ggctatcatt ttcatgtatt tgcagatgag accagacctc tattgcaggg cgccagactg
    18781 acagcatttg aacttcagtc ttccggtgtg gatgtcacac tgatctgtga caatatgtcg
    18841 gcgacagtca tgaagaacgg ctgggtcaat gcggtatttg tcgggtgtga ccgtgtggct
    18901 gcgaacggag atgcggcgaa taagatcggt acgtccgtag tggcggctgt ggcaaaatat
    18961 tacggtgtgc cggtgtatat ctgcgcgccg acgtcaacga tcgacttaaa tacgccgacc
    19021 ggagccggga ttacgatcga gcagcgtccg gcggaggaag tcacggaaat gtggtacaag
    19081 gagcgcatgg caccggaggg cgtcaaggtc ttcaacccgg catttgatgt gacggatcat
    19141 gagctgattg caggcatcgt taccgaatac ggtgtggcga gagcgcctta cacggagtcg
    19201 ctggtggcga tttttgcaga aaaggaaaag cgtgccagag agaaaaaaga agcctgatag
    19261 agaagatgta agcgatttaa ggaggaaaga atatgccaga gaacagtaat tgcagcggag
    19321 cgtccagctg ctcaaaggag agctgcgagg gatgtccgag caacgcgaag aataaagcag
    19381 gcggcggaat tgccaaggag ccgatgaatg cggcatccaa cgttaagaaa gtgatcggtg
    19441 ttgtcagcgg aaaaggcggc gtcggcaaat catttgtcac agcatcactc gctgcagcga
    19501 tgaaccgcgc cggatacaag gtaggcatca tggacgcgga tattaccggt ccgtcgattc
    19561 ctaagatgtt cggaattcat ggacaggtat acggaacgga cgacggaatg gttccgatgg
    19621 agacggagaa cggcatcaag atcatgtcga tcaacctgct gttggatgac gaggaggcac
    19681 ctgtcatctg gagaggtccg gtgattgccg gcgtggtaaa acagttctgg aacgagacag
    19741 tctggggaga cgtggactat ctgttcgtgg atatgccgcc tggaaccggc gatgtaccgc
    19801 ttacggtgtt ccagtcgctt ccggtagacg gaatcgtgat tgtgacgtcc ccgcaggaac
    19861 tcgtgcagat gattgtgaaa aaggcgtaca acatggcgga gatgatgcat gtgccggtgc
    19921 tcggtctggt ggagaatttc agctacctga agtgtccgga ctgcggaaaa gagattaagc
    19981 tgtttggcga gagtcatatc gacgatgtcg caaaagagct cgggatcccg gtattcggaa
    20041 agcttccgct tgatccggcg tttgcggagc aggcagacaa gggagcgttt gcaacgatgg
    20101 agaacgctta tctggatgcg ggcgtagaga agttaaagac actttaatgt gacaggaacg
    20161 ggaaagtgtt accacttacc cggagaaaat aacctcttgg tgtaaaactg tttacaccgg
    20221 gaggttcttt ttttatactg gaaccatcaa aggagttaca gagatgaaaa taaaaattga
    20281 gattgacgag agcgccgcgg aggatgaagt gattatccgc tgccgcggtc tgacgaaaca
    20341 ggtcgctgcc gtgcagcgcg ccgtgcggga tgtcaccaac gcttccgaga agatcctgct
    20401 ttataaaggg aacacggaat actatgtgac attgtccaag atcctgtttt tcgagacaga
    20461 cgagaacggg atcagcgcac acacccggga tgagatgtat cagacccggt acaaactata
    20521 cgagctggaa gatatgcttc cgggcgtttt tatgagagta tccaaatcca cgatcttaaa
    20581 cacggatcag atttactcta ttgaccgcaa tctgacggcg tcaagtgtgg tggcgttttt
    20641 aaacacgcac aagaaggtct atgtatcgcg gtattactat aaaccgttga ctcaaaaatt
    20701 agaagaaaag aggttgcatc atgaaaagta gcaaagtatt ctggggaatc ttttttatcc
    20761 tcgcagcagt gtatgtcgtt ataagcaagt ttggaattct gccggatatc ggcgtgttca
    20821 gcattattct gaccgtattt ttcctctggc tttttgtcga gggaatccgc aatgtgaatt
    20881 tctgggagat tctgttctcg attgcgttta tctgtatcat ctatgataag ccgcttggaa
    20941 ttacagcact cacgccgtgg acggtgctcg gcgcggcatt ccttgggagc atcggtctgt
    21001 cattgatctt tggcgggaaa aagcggaaat ggaagacggt gaccggcaat gtgggaacat
    21061 ccagcagtga acagtatacc ggcgaagaga tccggtgcga gaacagcttc ggttccgcaa
    21121 tccgctacat caactccgac aacttcagac gcgccgccat cgaaaataat ttcggatcgc
    21181 tttcggtgta cttcgacaat gcgatcgtgc aggaaggctc tgcaaatgtg agcgtggaga
    21241 ataatttcgg ggagactaac ctttacatcc cgaaagaatg gaagattcag aataatctgg
    21301 accgttcgtt cggcgccatc cgtgaaaccg gcagcagcat cggaacgagc agcacggtgc
    21361 tgtatctgaa tggctccgcg aacttcggag agattcatct gcactacatc tgataaatac
    21421 cgcggaaagc ggaagcggtg gggatcgcgg gcatcatgta aaaaggttta caacgtttca
    21481 gagtgcaacc ggagacggtc cattctttgg agcaaaatcc ttgtatttct tccgcagcgc
    21541 gtttgacatc ggattctgtg tcttggccac gttttgacaa tccgcgggat gtgttcgtca
    21601 cgccgcagac aatgagcgga cttcctggtg cccctagcgg caccgcttca cagacaatat
    21661 aaaaccgcgc gaaccgaaac tcgctggcat ctgctattga aaatagggca gatgccaact
    21721 cagacatcgg cttcgcgcgg ttatgttttg ttcagcggtg tcgacaaggg gcacacacga
    21781 aagtccttaa attgtctgcg gagtgcggac acatttcgcg gagtgctcaa aacttggaaa
    21841 gacacggatc atcgtggatg tcaaacgcgg tgcggattag aaataccgga ttatgcgatc
    21901 agaatgaccg ccgccggttg catcctgaaa cgttagaaaa cgtttttatg atccggcttc
    21961 gatccctgcc gcatccactt tctgcggcat ttttattcct ctgtatccgt gtagctggta
    22021 tcttcgtgaa gattcggctt catgtcaata ccgcggttcg cgtcacctgt gatgtctttt
    22081 ccgaagtgat agtcgttgcc cggcaggatg gcatttaaga aaatacctgc gatcgctgcg
    22141 actgccagcg cggtgagtgt gacggaggtt ccggcgatcg taaaggtaag accgtcggag
    22201 aaaccaagac cgcacacgaa gatcacgcct gcgatgatca gattgcgtga ctgcgtaaaa
    22261 tccacatgat tttccacaac attgcggacg ccgatggcgg agatcatacc gtagagcatg
    22321 aagctgacac cgccgatgat agcggacggc atggaaccga tcacagcagc catcttcgga
    22381 ataaagctta agatgatggc gtagcaggct gcgatgcgga tgacctttgg atcgtatacc
    22441 ttgctcagct cgagcacgcc ggtattttcg ccgtaggtgg tgtttgcggg acctccgacg
    22501 agagcggaca gggaagtggc gagtccgtca ccgatcaggg tgcggtgaag tcctggatct
    22561 tcgataaaat tctgatcaac cgtcgcggag atggcagaaa tatcgccaat gtgttccatc
    22621 atggttgcga gtgcgatcgg agccatgacc aaaatggcgg acagattgaa tttgcagagg
    22681 gaaaatgccg gtacgccgac ccaggaagcg tttgcgatgt cggtaaaaga aagaatggcg
    22741 gagccgtctg cgtttgtcat gcccatggcg ttgaagatca atgcggcaat ataagaaata
    22801 atgatgccca tcagaatcgg gatgatctta aacattcccc tgccccagat attgaaaata
    22861 atgatcgtaa ccagagcgat gagggcgaga agccagttgg tggaagcgtt gttgatggca
    22921 gaaccggcaa ggctcagtcc gatgcagatg atgatcggac cggttacgac cggcggaaga
    22981 aaacgcatga ccttcttgac accgacaagc ttgataatca gcgcgagaat cagatataaa
    23041 agacccgcga caacaattcc accgcaggca taggaaagtt tgtcagcgtt ggacatgtcg
    23101 gcgaatacac cggaatccat gtttgcaatc gtggcaaaac cgccgaggaa ggcaaaggaa
    23161 gaaccgagaa acgccggaac cttgaatttg gaacatagat ggaaaaataa agttccgata
    23221 ccggcacaga tcaatgtaac ctgtacatgt agaacatctt cgccgaagta gctgttgaca
    23281 agaattggta caagaatggt tgcgccgaac atggcaaaca tatgctgcag gccaagaatc
    23341 agcatttttg gtacgccaag tacgctggcg tcgcggattg ctccgtcttt ttcgttcata
    23401 gtaaactcct cctgatgtaa aatgattggt agttgcgtat atacaaatgg caaatcagaa
    23461 cttctgattt gccataagat atcaaaaaat agatccggtg aaacgtcttg cctcctgatc
    23521 gtaatcacgg acgggaatct ggtccagttc gccggtaccg tcgagataga aagtgagcag
    23581 cgtctgcgtc atataaggac tgatccagag agccgcaatg ccaaaagagc agatggcaag
    23641 cgcgccccag ccgagaaagc tgaataaaat gtaaagcagc ttcctgcgtc gtccgcgcat
    23701 aaatttacgg caggtgcgaa aagcatcccg cacgcttaaa tgcggatggt ctaaaagaaa
    23761 gaagaaaacc atgcggtagg taagcaacac acagaaagta aaaatcagac cgaggatgct
    23821 tccggcagca agcagggcac cggagagacc ggagacaccg gttttataaa aataaagaac
    23881 accggcaatg gcaggaatac ctgcgatcac cagaaataca tcgaagagaa cggcagcgag
    23941 aaagaagcgc tctgcgccat tgcgaaacgg tgtaaaaaca tcacggatgc ggtatgtctg
    24001 accgcgcgtc atattcatat gaaccagcat aacgccggtc tctagcatct gggcgatcag
    24061 aagaattaaa atatctgcaa tcgtgctgat gataagctgc ggagtgccgg gataatcgcc
    24121 gagcgtcatg gagaacggaa tctcgatgag cgtcggaatt aaggaggcag tcagaaatgc
    24181 tgccatcggt acggaataac ggttatttaa aatgtcgcgt gaaatacgtt ttaattcgct
    24241 ggatgatctt gacatgtgta gactcctgtg gatgtgatat ttgtgtatgt tctggtgaaa
    24301 gttttgcttt cgcgaacatt atattcctat agttacgcag tgcctgtggg tttgaaaatg
    24361 caaggcattt tcaaactcac gggcattcgc cctatcatcc atgaatgtta caaaatattg
    24421 tctgcaagca gccggatttt gtaacattca tggatggcac tgctcattgc tttcgcgaac
    24481 attatttccc tgtatctgcg cagatttttg cgcatccgaa gttccgcagg aacttctaat
    24541 atgaactcgc cagagttcat tatagcatgg aagaccgtga tatgctactg gcagttaaag
    24601 agatttggaa tccagaaacg tgcgcgtgct ttacaaccga aaatgcggcg gttataatag
    24661 cagggagtaa gataggaatg gagatcggaa tgtttcagac ggatagacgg gtagaccggg
    24721 atttttatat tatgggctgg tgcgcggcgg gaattttcgc ggcgctgttt ttgtttgtca
    24781 gagtaacagg aattccggtc tggaaatttt tgctgccctg cccgtttcat gcgctgaccg
    24841 gagcgtactg ccccgggtgc ggcgggacaa gagccgtcag ggcgctgctt gccggcaaat
    24901 ggctgcgctc ctttgtgctg cacccgtttg tgccgtatgc ggcgctgctt agcggctggt
    24961 ttatgatcag ccagaccatt gaacgcgtga gcggaagccg gatacggatt gccctgcgct
    25021 ttcgtgatgt ctatatatgg atcgccctgc ttttgatcgt ggtcaactgc ctggtcaaaa
    25081 atcttgccct gtttgtgtgg catgtggatt tactggccta gggaattcat cagtgtatca
    25141 aaatcgatgc cgagcgtgcc gtatacctga cgcgccatat tttccacgcc gccataatat
    25201 aattcggcaa tcgcaaatgt gtaaataatc atggcgagga caatgcccag ggcaatggcg
    25261 ccaaggatca gagcaatttt cgcgcgggag g
//
