LOCUS       c00016_NZ_JHYD..       23300 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JHYD01000025.1 Ruminiclostridium cellobioparum DSM 1351 = ATCC
            15832 T344DRAFT_scaffold00016.16_C, whole genome shotgun sequence.
ACCESSION   NZ_JHYD01000025
VERSION     NZ_JHYD01000025
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:46:04
            Original ID  :: NZ_JHYD01000025.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 25734
            Orig. end    :: 49034
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23300
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[35734:39034]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13300
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23300
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23300
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1061..2272)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ROK"
                     /gene_functions="other (smcogs) SMCOG1034:Repressor, ORF,
                     Kinase (Score: 190.2; E-value: 1.9e-58)"
                     /gene_kind="other"
                     /locus_tag="ctg16_24"
                     /sec_met_domain="ROK (E-value: 4.3e-58, bitscore: 190.2,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGKTGNNKFLKQFNETSLLELIRLNKQISKADLAQLTGLSPTA
                     CGVIVSNLLEKGYIREAGIGISKGGRRPNLYELNPKSYYSIGVDIDVDYIRFILMDITG
                     NVEYRDMISSRFDQSVSESIAFIEKKVRQIIERNAIREDRLLGVGVSVPGMVDNVTHEV
                     IFAPNLGWERVDLESMMSGMGNFPIYVDNEAICSAISENWIGCCTEQRDFVCINMKSGI
                     GSSIFADGNLYRGCSGSAGEIGHIMVDHNGPKCACGNYGCLETLVSSRSMVEKAQKLVR
                     QGLIADFSDELDINSINSIDFIIDAVKAGNESARVILVEAAGYLGLAVANLINTINPSR
                     IVLGKELVKFSEDILEHMRNIALAKALKYPASRVEILASELGEDSSALGAAIVPLKKLF
                     GHRL"
     CDS             complement(2390..3919)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_25"
                     /sec_met_domain="FGGY_C (E-value: 1.1e-42, bitscore: 139.2,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 1.5e-87, bitscore: 286.3,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSFLIGIDLGTSGVKTVLFDESGKPVASSTVEYPLYQPNLGWAEQ
                     DPEEWWRGTCESINNVMLKSGVDKREVKGVGLSGQMHGAVLLDKDDKVLRKAIIWCDQR
                     SAAECDQITELIGKERLIEITANPALTGFTASKIMWVKNNEPQIFEKIAKILLPKDYIR
                     LRLTGEYATEVSDASGMQLMNIAQRKWSDEVVGKLGISTSMLGKMYESQEVTGKVTASA
                     AAITGLNEGTIVVGGAGDQAAGAVGNGIVKPGVVSSTIGTSGVVFAYTDKLTIDPLGRV
                     HTFCHAVPNTYHIMGVTQGAGLSLKWFRDTFCMEELMTAELSDIDVYKLLDAEAETIKP
                     CSDGLIYLPYLMGERTPHLDPNARGVFFGLTAKHTKPHFVRAIMEGVTYSLKDCLEIIK
                     DMGVSVSEVRASGGGGKSGIWRQMQADVFGTGINRIKSDEGPALGVAILAGVGAGVYSS
                     VPEACEAIIQVKDTLAPIEANINRYNDFYKLYTKLYKSMKEDFTQLNNILK"
     CDS             complement(4201..4458)
                     /locus_tag="ctg16_26"
                     /transl_table=11
                     /translation="LKLYGRLVKRGKLLKEAWVVPQNGDGDFHDQLEECLIAVCKELDV
                     EVPIWLKKNTREFGLYRKTSFNSDHFGEAIGFDRLEIVLY"
     CDS             complement(4679..6244)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_27"
                     /sec_met_domain="HMGL-like (E-value: 4.9e-54, bitscore:
                     176.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNKLIIYDSTLRDGAQALGISFTVEDKLKIVNKLDNLGVHYIEA
                     GNPGSNPKDLEFFEKVLKLKLASSKIIAFGATRRANISVEEDANIQSLLKAGTEAIAVF
                     GKSWDFQVTDIIKTTLEENLRMIYDTIKYFKNHGKIVVYDAEHFFDGYNANPEYAMETL
                     KVANRAGADTICLCDTKGAGLPSHIARITGLVRDEVDCAIGIHCHNDNGMAVAGSIAAV
                     EAGAVQIQGTINGFGERCGNANLCTIIPNLQLMMNYECIPAANMEKLTPTARYVSEVAN
                     IIHDERAPFVGNCAFAHKAGMHADAVNKNTSAYEMIHPEVVGNQRNILMSEVAGRSAVM
                     SIINMVDSTLTKDSPETKKIIERLKELEYEGYQYEGAESSFELVIRKMLGKYKTFFELK
                     EFKVIVNEPTVNSVNSSAMIKILVDGQTEITAAEGDGPVNALDKALRKALERFYPRIAE
                     MKLTDYKVRVLDSNFATASKVRVLIETTDGQDAWTTVGVSTDIIEASWRALVDSVEHKL
                     MKEN"
     CDS             complement(6260..7045)
                     /locus_tag="ctg16_28"
                     /transl_table=11
                     /translation="MDTGKGFLLIWVLVTLHVLGDFYLQTEKIARNKKTSYRGVVVHSV
                     QYGIPFILALVFIRFGALLLLCLLLSVLAHFMVDSLKYWTTENNFFKGYHKRPAVVFMA
                     DQLLHIFLLLLIALLYVKVSWQSPLLHLNKIWSDLLGMVNINPVNAIKWLLVGLLIIKP
                     ANITFNLFFSAFKPEEEAARDVKQQRTGAIIGTLERILIVFFISINQFSALGFILTAKS
                     IARYDAIAKDRAFAEYYLIGTLVSVVFSVAAYILVFTGL"
     CDS             complement(7089..7739)
                     /locus_tag="ctg16_29"
                     /transl_table=11
                     /translation="MYFAVIGDIKNSRKIKDRFQVQEQLEQVLEEINSEFDNYIAAKFI
                     VTLGDEFQGLLNSTQPIIRIIERIMLKMYPVKIRFGIGFGDISTKINREMAIGADGTAY
                     HHARRMINEIKKSHKSRRSDQTSVKIAADDNISIVALANSTFSLWSLIQGKWTQKQVRL
                     ILESVICEDNQREVARRLGIVQSTVQRGLKSSGYYSYLHTKRVLEEVLLREWG"
     CDS             complement(8042..9580)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_30"
                     /sec_met_domain="HMGL-like (E-value: 2.1e-100, bitscore:
                     328.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARRIRIFDTTLRDGEQTPGVNLNLQEKMEIAKQLARLGVDVIEG
                     GFAIASPGDFESIMMLSKNIKGVSIASLCRATEKDIDRAWEAVQYAESPRIHTFIATSD
                     IHMKYKLKMTEEEVFERAVAMVRRAKSYCSDVEFSAEDASRTREDFLIRIVEAVIAAGA
                     TVVNIPDTVGYTTPVEFGRLIRNLRNNVPNIDKADISVHCHNDLGLAVANSLAAVENGA
                     VQVECTVNGLGERAGNAAVEEIIMGIDTRKDYYDITHKIDTTQIYRTSRLVSSLTGVGV
                     QPNKAIVGANAFAHESGIHQHGVLSEKSTYEIMTPESVGVGKNRMVLGKLSGHHAFEDR
                     LKEMGYVLSAEEVKAAFEKFKDLADRKKIVTDKDIEALVDENIAVPEIFVIDSFQINSG
                     NKMISTSTVSIRRENEVITEAATGDGPVDAAFNAIERATDVKAELVHYSIKAVTEGKDA
                     LGEVTVKISSNNSVYMGKGVSTDIIEASVKAYLSAINRSISEIGKISEEAIISR"
     CDS             complement(10001..10996)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_31"
                     /sec_met_domain="IlvN (E-value: 1.5e-76, bitscore: 248.7,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 9.1e-70, bitscore: 226.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARMYYDSDCNLKLLEGKTVAVIGYGSQGHAHAQNLKDSGVNVIV
                     GLTPDSARRKQVESDGLKVYDTAAAAKMADVIMILIPDEKQKAMYYESIAPNLEEGNIL
                     MFAHGFNINFNQIIPPADVDVIMAAPKGPGHTVRSQYREGKGVPALIAIAQDASGKARD
                     YALAYAAGIGAGRAGILETTFREETETDLFGEQAVLCGGVTELMKAGFETLVNAGYQPE
                     IAYFECVHEMKLIVDLINQGGFAEMRYSISDTAEYGDYVTGKRIITEETRKEMKKVLKE
                     IQDGKFATNWVTENNAGGRANFLAMRRNEAEHQVEKVGAELRKMMSWLKK"
     CDS             complement(11122..11631)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_32"
                     /sec_met_domain="ALS_ss_C (E-value: 1.5e-32, bitscore:
                     104.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKHTLSVLVENRSGVLSRVAGLFSRRGFNIDSLAVGVTENPEVS
                     RMTIVVNGDEYTVEQVSKQLNKLIDVIKIRELENSDSVSRELALIKVNATAATRSEIIQ
                     IVEIFRAKIVDVSKNTLTVEISGSTDKVEALEDMLKQFGVKEIVRTGTIAIERGNKYIK
                     AGNTEE"
     CDS             complement(11675..13300)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_33"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2e-44, bitscore:
                     144.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLTGAQAMVKALELEGINIIFGYPGAAICPFYDALLDSEITHVL
                     TRNEQGAAHSASGFARVTGKPGVCVATSGPGATNLITGIATAYSDSIPMVAITGQVSLE
                     LIGRDVFQEVDTTGATAPFCKHNYLVKDVRELPRIIKEAFHIASTGRPGPVVIDVPVDI
                     QTQKLDFNYPEIVEIKGYKPNYKGHPQQIKRIAEAISKSKTPVICAGGGVVTAEATDIM
                     TSFAEKCGIPVVTTLMGIGAIEGDHPLNLGMLGSHGVFAANYAVNRTDLLILIGARVGD
                     RALGTAEKIAEKAKIIHIDIDPAEIGKNVSTAIPVVGDAKLILEALSSVIQPGDTSDWV
                     KEVKRVKAEKLEKPKAGDKDTVNPRLVISLLSERLDTSAILATEVGQNQIWAANNFTAK
                     RPGAFITSGGLGTMGYGLPAAIGAKLGSPDSTVVIVGGDGSFQMSMPEMGTIKQSKIGI
                     KILILNNSRLGMVREIQKNKYNRRYSQVFMNDNPDFVKLAEAYGFQAEKITADSQINAA
                     LDRFLADDSTYLLECIVDPDEPTI"
     CDS             14067..19220
                     /locus_tag="ctg16_34"
                     /transl_table=11
                     /translation="MKRILSIIMVIALVLANLSLNVQKVFAASPAPAAGNIIITNNLTG
                     KSDTIYIFGLDPGTLVKVYTASTGNKILTYGTVSKSKSEITLSVPQIGTDEGSLYISVI
                     EKGNTESGRTKADYPAEPRSGAIDPKAVTITNNAQKSDVIYVSGLTPRDVIKVYSAETG
                     GKLLGSKTVSTSGSDVTITVPQVGSAEGSVYVTVTSKGYLESKRTEVPFKAEPASAPLD
                     PDNIVINNNAKSADTVYIPGLSAGDVVKIYNDSGKVLATKTVGSSAYDATISVPQLGVD
                     AGIVYITVTSKELAESSSVPVEFEGELASEKPNSGFITVTNNSGKADTVYVTGLSPSDV
                     VKVYNKETKGSLLGQATVTSSGNEATVSIPQLGSSSGVVYVTVTNAGRNESQRVKISYS
                     QEGSSTDIAPSNITVTNNVGKADTVYVSGLVSGDVVKVYDAEYTGNLLGSATVAKSATD
                     VTISISQLGTDSGSVYVSITTSGKLESSRVPAEYLAESKSNSLDSNSVTVTNNSGAADT
                     IYVTGLTEGTLIKVYNAPASGSLLGSATVATSKTDATVTISQLGIAGGSVYLTITQPGA
                     QESGRTKIDYSAEGTSTEPNINNISISNNVGKADTIYVSNLTPGDIVRIYNAPSQGNII
                     GTATVASSAADVTVSIAQLGTAAGSVYVTVTSTGKAESKRTKADYKAESVYVDVDSSNI
                     TVTNNAGKADTVYFTRLSAGDVVKVYDSLQGGTLLGSATVAAGSTDTTVSIPQLGKGAG
                     SVFVTVSSTDKSESARKEVTYTGEASSVDLSESQIVVTNNISGTPDTIYVSGLSPEDVV
                     KAYSAQNQGILLGSATVPAAGTDATITVTQLGSAKGSVYITVTSSGKLESNRTKADYSD
                     EGKSTEPDSNNITINNNSGAADTVRVTGLTAGDVVRVYSAETGGNLLGSATVTTYSSEA
                     TVTITQLGTAAGKVYVTVAGTNKAESKRITADYDAEPVSGKLDSSRITVTNNAGSADTV
                     RVTGLTPGDVVKVYSLSSGGNLLGSATVAASSTEATVEIAQLGTAEGKVYVTVTSVNKA
                     EGERTDAAYKAEEASTSPDPAKVSVANNYGIASTITVGGLKDNDVVSIYSAESGGTLLG
                     KGTVATYNSEVTISVSQLSDTGGDVYITVTTPGKLESNRAKVTYEAKAASTPPDASNVE
                     IYNNVGFADTITVFGMEPNAVIKVYTQATGGNPIGTATVPADSTEATISITQLGVNDGV
                     VYISVTTKGKTESGRAAISYTKESASEPLAAGNVKITNNSGMSDTIVVTGLLAYDTIKI
                     YNSETDGTRLATAVADENTLAAAANISQLGTGAGKIYITVTNYGRSESARTAVEYEAES
                     TAPLASNIFIVNNAGIADTITVKGLNDTDVVKVYDAASNGNLIGAATVPPGSSMATMSV
                     TQLTSAAGKVYVSVTNYGRAESSLTKAEYISETSTMAPYIGDIYIVNNVDINDTITVYN
                     LLSGDVVKVYDSAVGGNLLGNASVANNKTEATVSVEDLGSAAGTVYVSVITKGKTESVR
                     TEAGYVAESRSTAPYAGNIYITNNVTLSDIIQVSGLTAGDKVKVYDSESGGELLGSATA
                     SSGSDQVKITVKQLGESAGSVYVSVTSKGKTESKRTEAEYVSEQTTNEPYAGYISVSNN
                     PTGTSDTVTVTNLNGGDIINVYSAAAGGSLLGSATVASGSTTGTVVISQLGTASGSVYI
                     SITSAGKAESNRTKADYPAE"
     CDS             complement(19312..19668)
                     /locus_tag="ctg16_35"
                     /transl_table=11
                     /translation="MINRKLITREQAVRAIETGEFGNDILTSKPRVVIILTQDWCPQWH
                     DMRGWLYGHDTREDIDIYELEYNKTDFFDEFRNFKENRLGNDTIPYVRFYKEGVLYRES
                     NYISEGQFFEILSM"
     CDS             complement(19761..20219)
                     /locus_tag="ctg16_36"
                     /transl_table=11
                     /translation="MYTRNEQFMLKALRQAELAFSKGEAAVGAVIVKDGVIISRGHNKK
                     EARLDVTSHAEIEAIKKAAKKLGTWRLDGCDMYVTLEPCPMCAGAVIQSRIRTLYIGAM
                     DNRAGAAGSVVDLFRIPRFNHRVDVVIGLLHEQCTELLKKFFVELRQK"
     CDS             complement(20322..22049)
                     /locus_tag="ctg16_37"
                     /transl_table=11
                     /translation="MLLSRLLGERLKEKPGEASIISHVFLLRGGYVRQVANGIYSMLMP
                     ARRISRKIENIIREEMDRIDGQEVLFPVVLPAELWQESGRFESIGSELMRMKDRSGRDM
                     LLGMTHEEAAVHLARSEAMTYAKYPFMIYQIQTKFRDEPRSRGGLIRVREFTMKDAYSF
                     HTSQEDLELYYNKVFDSYHKIFERAGLPQVVSVASDTGMMGGNVAHEYMLLAESGEDSI
                     IVCDSCDYRANMEVAASKTVCRSGEDSQTAGDAGMDQQIEEVYTPDMKSIDDICRFLKV
                     EAAKLIKATVFSVENSKKPLIVFIRGDLQVNEAKLKRVVKANVFPYDERVDGNCGICFG
                     FIGTRGIDTKNNTILFDESLKGQFNMVTGANKADYHLIGINVERDIRPESYVEVAKVNE
                     GDTCIKCGGRLSVKRGIEVGNIFQLGTKYTESMNMAYTDNDGRQRHPVMGCYGIGIGRL
                     LACIIEAHHDDCGPIWPKSIAPWQIHICMINKKNDDVRKTGFEMYDKLSRRYEVIMDDR
                     DVQAGIQFADADLLGIPLRLIVSSRNLEQGEVEVVSRDKTLREKVRLEELESFLEKVV"
ORIGIN
        1 gcccagaccg cctgccttca atacttcata cattgcaaga gcagcatcat aaaggttggt
       61 cgggaattgg tcggtatccc agcccagcaa tacatcaccc tggttagcat caatgcttcc
      121 cagcatattg ttgattctgc agactgccag ctcgtgctgg aaggtatgtc ctgccaaagt
      181 cgcatggttt gcttcaatgt tgagcttgaa gtatggatcc aaaccgtatg tcttcaggaa
      241 gcctataact gtacctgcat caaagtcata ctggtgtttt gtcggttcct tcggcttggg
      301 ttcgataagg aactgtccgt tgaagcctat ttccctggca taatcaacag ccatcttcag
      361 gaatcttgcc aggttatcca gctcaagctt catatctgta ttcaaaagtg tctcataacc
      421 ttctctgcca ccccagaata catagttttc tccgcccaat tcctttgtga tttccatggc
      481 cttcttaacc tgggctgcag caaatgcaaa gatatcggca tttggtgaag ttgatgcacc
      541 atgcatgaat cttggatttc caaatgcatt tgttgttccc caaagaagtt ttacatcgct
      601 ggatttcatt ctgtccttta tggcagaaac gatcacgtcc aggttcttgt ttgtttcggc
      661 aagagtatct ccttcgggtg caatatccct gtcgtggaag cagaagaatg gaactcctat
      721 tttttcggca aactcgaagt ttgcttcaac cttgaatttt gcgccgtcca tggcagacat
      781 tgtgttccat ggtctttcgt aagaacctgc accgaacata tctgctccgg cagctgcaaa
      841 agtatgccag taagctactg caaatcttaa atgctccttc attgtctttc cgcctataac
      901 cgcatcggga ttatagtact tgaatgccaa tggattatcc gatccaccgc cttcatactt
      961 gatttttgaa attccgctga aaatttccga cataataccc tccatctgcg tgctttgcac
     1021 gctgctaaat agtaaattaa ttatgtttat atttatgctc ctacagcctg tggccaaaga
     1081 gctttttcaa tggtacgatt gcagctccaa gtgccgagga atcctctccc aattccgacg
     1141 cgagtatctc aacccttgat gccggatatt tcagtgcctt tgccagtgca atgtttcgca
     1201 tatgctccaa aatatcctct gaaaatttca ccaattcctt cccaagcact atcctggaag
     1261 ggttgatggt atttattaaa tttgctaccg caagacccag gtatccggca gcttccacca
     1321 gaatgactct tgcggattcg ttacctgcct ttacggcgtc aatgataaaa tcaattgaat
     1381 ttatggagtt tatatccaac tcatccgaga aatcggctat aagtccctgt ctcacaagtt
     1441 tttgcgcctt ctcaaccatc gatcttgagg aaaccagggt ttccaggcag ccatagtttc
     1501 cgcaggcaca tttgggtccg ttgtgatcca ccattatgtg accgatttct ccggcacttc
     1561 cgctgcagcc cctgtagaga ttgccgtctg cgaatatgct ggagccaata ccggatttca
     1621 tgtttataca tacaaaatct ctttgttcgg tacagcagcc tatccaattt tcacttatgg
     1681 ccgaacatat ggcctcattg tccacatata tggggaaatt gcccatgccc gacatcatgc
     1741 tctccagatc gactctctcc caccccagat taggtgcgaa aattacttcg tgggttacat
     1801 tgtcaaccat acccggcacc gacacgccaa cacccagtaa tctgtcttcc ctgatagcat
     1861 tccgttctat aatctgccgt acttttttct caataaacgc tattgactcc gataccgact
     1921 ggtcgaatct actggagatc atatccctgt actcaacatt tccggttata tccatgagga
     1981 taaatctgat atagtcaaca tctatatcaa ctcctatgga ataatagctt tttggattga
     2041 gttcatataa gttgggcctt ctcccgcctt ttgatattcc gataccggct tcacggatat
     2101 agcctttttc cagcaggttt gaaacaataa ctccgcatgc ggtgggagac agacctgtaa
     2161 gttgagccaa atcagctttt gatatctgtt tgttgagcct tatcaattcc agcagggaag
     2221 tttcattaaa ttgcttcaaa aacttattgt tgcctgtttt acccaacttc atattcctcc
     2281 cccctcccac tgtattaata aaatttaaat gatcaactta ttttcagact ttgtaaactc
     2341 agtttataat gtaaaaatca tgcaattcct gcagctgctg cttcaaagtt tatttaagaa
     2401 tgttattaag ctgggtaaag tcttccttca tggatttgta cagctttgta tataacttgt
     2461 agaaatcatt gtacctgtta atatttgcct cgatgggagc aagtgtatcc tttacctgga
     2521 taatcgcttc gcatgcctcg ggcacactgc tgtacacccc ggcgccgaca ccggcaagta
     2581 ttgcaactcc aagagccgga ccttcgtctg attttatcct gttgatgcct gtaccaaata
     2641 catcagcctg catctgtctc cagatgccgc tctttccgcc gccgcccgat gccctaactt
     2701 cggatacgct gactcccatg tctttgataa tttccagaca gtccttcagg ctgtatgtta
     2761 cgccttccat aatggcacgt acaaaatgag gttttgtgtg tttggcggtc aatccgaaga
     2821 aaactcctct tgcatttgga tcaaggtgcg gagttctttc tcccatcagg tacggtaaat
     2881 atataagtcc gtcactgcat ggcttgattg tttcagcctc cgcatccaga agcttgtaga
     2941 catcaatatc ggataattcc gcagtcatga gctcctccat gcagaaagta tccctgaacc
     3001 acttcaagga caaaccggct ccctgcgtaa cgcccattat atgatatgtg ttgggaaccg
     3061 catgacagaa agtatgcact cttcccaggg gatcaattgt cagtttgtct gtatatgcaa
     3121 aaacaacacc cgaggttcct attgtggatg atactactcc cggtttaact ataccgtttc
     3181 caaccgcacc ggcagcctgg tctccggctc ctcccacaac tatcgttcct tcattcagac
     3241 ctgttatggc agctgcggaa gctgtaacct tacccgtaac ctcttgtgat tcatacatct
     3301 tgcccagcat ggaagtggat attcccagtt ttccgactac ttcgtcactc cattttcttt
     3361 gggctatatt catcagctgc ataccgctgg cgtctgaaac ctctgttgca tattcaccgg
     3421 taagcctcaa tctgatatag tcctttggca gtaatatctt tgctatcttt tcaaaaatct
     3481 gcggctcgtt gtttttgacc cacatgatct ttgaagctgt aaaccctgta agtgccggat
     3541 tagctgttat ttcaatcagt ctttccttgc cgataagctc tgtgatctgg tcacactcgg
     3601 cagcacttct ctgatcgcac cagatgattg cttttctgag aaccttgtcg tctttgtcaa
     3661 gcagaacggc tccatgcatt tggcctgata agcccacacc ctttacttcc cgcttatcaa
     3721 cgccgctttt taacataacg ttgtttatgc tttcgcatgt acccctccac cattcctcag
     3781 gatcctgttc tgcccatcca agattgggct gataaagtgg gtactccacg gtggaacttg
     3841 ctacaggttt gccgctttca tcaaacaata cagtcttaac acctgaggtt ccaagatcga
     3901 taccaattag aaaagacaat gtatagtccc cctttccaaa gtttacttta taatattata
     3961 ttataaagta tatcaattat ttgctgttat gtcaaaatga ttttatgaaa aagcacaggt
     4021 ttttatttta actttatcaa caatatccca cataacagca aaaacacgca taggcttcaa
     4081 aaccatgcgt gtttagaatt tgcattttaa ctgctaataa tacattttat agcttgcatt
     4141 tgaaagaatt ttacagcttt cattacccgg tatctgaatt tatgggataa aagttaaaat
     4201 ttaatacagc acaatctcaa gcctgtcaaa gcctattgct tcaccgaaat ggtcgctgtt
     4261 aaagctggtt ttcctgtaga gcccgaattc cctggtattt ttcttcagcc agatgggcac
     4321 ctccacatcc agttccttgc aaaccgctat gaggcattcc tccagctgat catggaagtc
     4381 cccgtccccg ttctggggaa cgacccaggc ttccttcagt aattttcccc gcttgactaa
     4441 tctgccgtat agtttcaact ctttgatccc cttaaactta tttattaata ctattatata
     4501 aagccacctt tattattacg cataggttca atagaaaatt tttacctaaa ctgcgtttca
     4561 atgaggccat atgatgctca tagtactctt tggattacct tgttcttcat aagcctcatt
     4621 atataccaaa attaataata atagaagtca ggaatcaacc ggccgcatat ggctgattct
     4681 aattttcctt catcagctta tgttccaccg aatccaccag tgcccgccag ctggcttcaa
     4741 ttatgtcggt ggatactccg actgttgtcc aggcatcctg tccgtcagtc gtctcgatca
     4801 aaacacggac cttggatgca gttgcaaaat tggaatccaa tactctaacc ttatagtcgg
     4861 tcagtttcat ttcggctatc ctgggataaa aacgctccaa agcttttcta agtgccttgt
     4921 caagagcatt taccggtccg tcgccttcag ctgcggttat ttcagtttgc ccatccacaa
     4981 gtatttttat cattgcggaa gagtttacac tgttcacggt aggttcattt acaataacct
     5041 taaactcctt cagctcaaag aaagtcttgt attttcccag cattttgcgg atcaccagct
     5101 caaaggagct ttcggcgccc tcatactgat agccttcata ctcaagctct ttaagccgtt
     5161 caatgatttt tttggtttcc ggagagtctt tggtcagcgt actgtccacc atgtttataa
     5221 tgctcattac agcacttctt cccgccacct ccgacataag gatattgcgc tggtttccaa
     5281 ccacctccgg atggatcatt tcgtacgccg aggtgttttt gttgacagca tctgcgtgca
     5341 tgccggcttt atgcgcaaat gcacagtttc caacgaaagg cgctctttcg tcatgaatta
     5401 tattggcaac ctcacttaca tatcttgcgg taggtgtgag cttttccata tttgctgcag
     5461 ggatgcactc ataattcatc atcagctgga ggtttggaat gattgtacac aaattcgcat
     5521 ttccgcacct ttctccaaag ccgttgatgg tgccctgtat ctgtacggcg cctgcctcaa
     5581 cagctgcgat cgatccggcc actgccatcc cgttgtcatt gtggcaatgt atccctatgg
     5641 cacaatccac ttcatcgcgt accagaccgg ttattctggc tatatgggaa ggaaggccgg
     5701 ccccttttgt atcacacagg caaatggtat ctgctcctgc tctgttggca acttttaagg
     5761 tttccatggc atattcggga tttgcattat acccgtcaaa aaagtgttcg gcgtcataaa
     5821 ctacaatctt tccgtgattt ttgaaatatt tgatggtatc gtatatcatt ctcaaatttt
     5881 cttccagcgt ggttttaata atatcagtga cctgaaaatc ccatgacttg ccgaatacag
     5941 ctatcgcttc ggtgccggcc ttcagcaggg actgtatgtt tgcatcctct tcgacactga
     6001 tgttggctct cctggtagca ccaaaggcta taattttgga actggccaat ttaagcttca
     6061 gcactttttc gaaaaattca aggtcttttg gatttgatcc cggattaccg gcctcaatat
     6121 agtgaactcc caggttatcc aatttattta ctatcttgag tttatcctcc acggtgaagg
     6181 aaatccccag ggcctgagct ccgtccctca gggttgaatc atatattatc agtttgttag
     6241 tcatactttt ctcctttctt tatagtcccg taaagaccaa tatatatgct gctactgaaa
     6301 acacaacgct tacaagggtt ccaatcaaat aatattccgc aaacgccctg tcctttgcta
     6361 tggcatcata tctggcaatg gattttgccg ttaatatgaa accaagtgca gaaaattgat
     6421 ttatactgat gaaaaataca ataagtatac gttcaagagt acctattatt gccccggtac
     6481 gctgctgttt tacgtccctt gccgcctcct cctccggctt aaaggccgaa aagaacagat
     6541 tgaaggttat atttgcgggc tttattatca gcaggcccac cagcagccac ttaattgcat
     6601 taaccggatt aatgttaacc attcccagca agtccgacca aattttattc aggtgcagca
     6661 aaggactctg ccagctcact tttacataca gtaatgctat taacaacaat aaaaatatat
     6721 gtaacagctg gtctgccata aatacaactg ccggcctctt atggtatcct ttaaaaaaat
     6781 tgttttcggt ggtccaatac ttcagagagt caaccataaa gtgggccagc accgaaagca
     6841 gcaaacacaa cagcagcaaa gcaccaaacc tgataaatac cagggcaagt ataaacggta
     6901 tgccatattg tacggaatgt acaacaaccc cccggtaact tgttttctta tttcgtgcta
     6961 ttttctctgt ttgcagataa aagtcaccta aaacatgcag ggttaccaac acccatatca
     7021 gtaaaaagcc cttacctgta tccatactca accctcccaa aaaatttatc cggtgcccct
     7081 ttgcaggtct atccccattc tcttaaaagc acctcttcca aaactctttt ggtatgcaga
     7141 tagctgtaat accccgaact cttcaagccc ctctgaacag tggactgaac tattccaagc
     7201 ctgcgggcaa cctctctctg gttgtcttcg caaatgacag attcgagaat aagtcttacc
     7261 tgcttctgag tccactttcc ctgaataagg gaccagaggc tgaaagtgct gtttgccagc
     7321 gcaactatac ttatattgtc atcggcggcg attttaaccg aagtctggtc gctcctcctg
     7381 cttttatggc tttttttgat ctcatttatc atgcgccttg catggtgata agcggtcccg
     7441 tcggctccta ttgccatttc ccggtttatt ttagtcgata tatcaccaaa tccgatcccg
     7501 aatcggattt ttacaggata cattttaagc attattcttt caattatcct gattatgggc
     7561 tgtgttgaat tcaagagtcc ctgaaactca tcccccagag tcacgatgaa tttagcagct
     7621 atataattgt caaattccga atttatttct tccaatacct gttcaagctg ttcctgcacc
     7681 tgaaagcgat cctttatttt acgggaattt tttatatccc cgataacagc aaaatacata
     7741 ttctacctcc cggacttact tcgagtatat attcagctat aacagtatca cattcaaaca
     7801 gtaaattcaa caaatttgat gcattatcag gtgcatcaaa tttgttattg catatgtgga
     7861 tgcatcattt cacattttgc attaattcat gcatcataat tcaaagctgc agcagatcaa
     7921 ttttccggtg tacacattca aactcagtat tataagtgcc tcgtcactgc tccaaaagtt
     7981 ataaattccc atatactaaa aaaagcagcc cttttagggg ctgcttcagc ttcaagcgcc
     8041 cctaccggct aattattgcc tcttcactta tcttaccgat ctcgcttata gatctgttta
     8101 ttgcactgag ataggcttta acacttgctt caattatatc cgtgctgaca cctttaccca
     8161 tgtataccga gttgttagag gatattttga cagtcacctc tcccagggca tccttacctt
     8221 cggttacagc tttgatgctg taatgcacca gttcggcctt aacatccgtc gcacgttcta
     8281 tggcattgaa ggcagcatcc acaggaccat ccccggtggc ggcctcggtt attacttcat
     8341 tctctctcct tatgctgaca gttgaggtgg atatcatctt attcccgctg tttatctgga
     8401 agctgtcgat tacaaatatt tcgggcacag caatattttc atccaccagt gcttcaatat
     8461 ccttgtcggt gactattttc tttctgtcgg caagatcctt gaatttctca aaggcagcct
     8521 tgacttcctc ggcagacaat acatagccca tttccttcaa tctgtcttca aaggcatgat
     8581 gacctgaaag ctttcccaga accatcctgt ttttacccac acccaccgac tcgggagtca
     8641 ttatctcata agtggatttt tctgaaagaa ctccatgctg gtgtattcct gattcatggg
     8701 caaaagcatt tgcccccact atggctttgt ttggctgtac acccacacct gtaaggcttg
     8761 aaacaagcct gctggttctg taaatttgtg tagtatctat tttatgagtt atgtcatagt
     8821 aatcttttct tgtgtcaatg cccattatta tttcttcaac agcggcattg ccggctcttt
     8881 caccaagacc gttaacagta cattctacct gtacggcgcc attttccaca gcagccagtg
     8941 aattggccac agccaggcca aggtcgttat ggcagtgaac actgatatcg gccttatcta
     9001 tgtttggtac attgtttctc aggtttctga tcaatctgcc gaactccaca ggtgtggtat
     9061 accccacagt atcgggaata tttactacag ttgcaccggc ggcaataaca gcctcaacta
     9121 tccttatgag aaaatcctca cgggttctgc tggcatcttc agctgaaaac tccacatcgg
     9181 agcaatagct ttttgcacgc ctcaccatgg ctacggcacg ttcaaaaacc tcttcctccg
     9241 tcatcttcag cttgtatttc atgtgtatgt ccgaagttgc tatgaaagtg tggattcttg
     9301 gactttctgc gtactgtacg gcttcccatg ccctgtctat atctttttcc gttgcacggc
     9361 acaggctggc tatcgaaact ccctttatat tttttgagag catcataatg gattcaaaat
     9421 ctcccggtga agctatggca aagcctccct cgataacatc cacgcccagt ctggccaatt
     9481 gcttggcaat ttccattttc tcctggagat tcagattaac acccggagtc tgctctccgt
     9541 ctctcagtgt ggtatcaaat attctgatcc ttcttgccat agaaataccc tccttccagg
     9601 gaacactcag ttcccttcat tctaacattc ataaacgtct aaaatcagta aatttttatc
     9661 agcttgttgt tggcactatt aaaacccttt atacaacaag tacttccgta cagacatata
     9721 taaatggatt gcttacaaaa tagatgctcg tattagtaaa ggcttataac aggccaaatt
     9781 agccgtcgct tacattcgcc atcctggctc atagtaaagc taaaaccagc gtcgtgcagg
     9841 ttttccggct actttgctgt tctcgcctac taatccatgc acctatttta attaagcttc
     9901 ccatttatat atgctacact cgcgtacttg ctgtattatt agattttttc aacaacaaaa
     9961 attaataaaa ttttaatgga atttttccat ctctatatgt ttatttcttc agccagctca
    10021 tcatctttct gagttctgcg cctacttttt ccacctgatg ttctgcttca ttccttctca
    10081 tggcaaggaa attcgccctt ccgcctgcat tgttttcagt gacccagttt gtagcgaact
    10141 ttccgtcctg gatttcctta agtactttct tcatttcttt tctggtttcc tcagtgatta
    10201 ttctcttacc tgtgacataa tcgccatact cggctgtgtc actgattgag tatctcattt
    10261 cagcaaaacc gccctgattt atgagatcta ctataagctt catttcatgc acacattcga
    10321 agtaggcaat ttcaggctga tagccggcat ttacaagtgt ttcgaagccc gctttcatca
    10381 actcggtaac tcctccgcaa agcacagcct gttcaccgaa caaatctgtt tctgtctctt
    10441 ccctgaaggt agtttcaagt attcctgccc ttcctgctcc tatacctgcc gcataagcga
    10501 gcgcgtaatc ccttgccttg cctgatgcat cctgagctat tgctatcaat gcaggaacgc
    10561 cttttccttc cctgtactgg ctccttaccg tatgtcccgg gccctttgga gcggccatta
    10621 taacatcgac atcagccggc ggtatgatct ggttgaaatt gatgttgaag ccatgggcaa
    10681 acataagtat attgccttct tccaggtttg gagcaatgct ttcatagtac attgccttct
    10741 gcttttcatc aggtattaat atcattatga catcggccat tttagcggcg gcagcagtat
    10801 cataaacctt taagccgtcg gactctacct gctttcttct cgccgaatcc ggagtcagac
    10861 ccactataac attaactccg ctatccttaa ggttctgcgc atgtgcgtgt ccctgacttc
    10921 catatcctat taccgccacg gttttacctt ccagtaactt caaattacag tcgctatcgt
    10981 agtacattct tgccatttta acttacctcc tagtttttat attacaattt aaacactgca
    11041 agtatttata tttttaaacc cattataccg gcgaagtatt caggcactta aagcattccg
    11101 tccggtatgt gaggattttg gctattcttc ggtgtttccg gcttttatat atttgttacc
    11161 tctttctatg gcaattgtcc ccgtacggac tatttccttt actccgaact gcttgagcat
    11221 atcctccaga gcttccacct tgtcggtaga gcccgaaatc tccactgtta acgtattttt
    11281 tgatacatca acgatctttg cacggaatat ctcgactatc tgtataattt ccgatcttgt
    11341 cgccgctgtg gcattaactt ttatcagggc aagttcacgg ctgaccgaat cagagttttc
    11401 cagctctctg atttttatga catcaatcag tttgttcaat tgcttgctta cctgttcaac
    11461 agtgtattca tcaccgttta caactattgt cattcttgaa acctccgggt tttcggtcac
    11521 tccaaccgca aggctgtcaa tattgaagcc cctcctgctg aacaggccgg ctactctgga
    11581 caaaactccc gaacggtttt caaccagtac cgatagtgtg tgctttgcca tcttcattcc
    11641 tcctcatcaa gaaaattcta tacgcttata tacgctaaat agtcggctca tccggatcaa
    11701 caatacactc cagcaaataa gtactgtcat ctgccagaaa tctgtccaat gccgcgttta
    11761 tctgggaatc agccgtgatc ttttcagcct ggaagccata ggcttcggcc agttttacaa
    11821 aatcaggatt gtcattcatg aacacctggg aatatctcct gttatatttg tttttctgta
    11881 tctcgcgtac catcccaagc ctcgaattat tcaaaatcag tattttgata cctattttac
    11941 tttgctttat ggtccccatt tcaggcattg acatctggaa actgccgtca ccgccgacga
    12001 taaccactgt actgtccggg ctgcccagct ttgcacctat tgcagccggc aaaccgtacc
    12061 ccattgttcc cagaccgccg gaggttataa atgctccggg ccttttagcg gtgaaattat
    12121 ttgcagccca tatctggttc tgtcccacct ctgtcgcaag gatggccgaa gtatcgagcc
    12181 tttctgagag caggcttatt accagcctcg gattgacagt atccttgtca ccggctttgg
    12241 gcttctcaag cttttccgcc ttgactctct tcacttcctt cacccaatcg gaggtatctc
    12301 cgggttgtat cacactgctg agagcttcca ggatgagttt tgcatctcct accaccggaa
    12361 tggcagtact tacatttttt ccaatctcgg caggatcaat atctatatga attattttag
    12421 ccttctcggc aattttttca gctgtaccca aagcgcggtc ccccactctg gcacctatca
    12481 atataagcag atcggttctg tttactgcgt aatttgcggc aaacacccca tgggacccca
    12541 gcattcccag gttcagcgga tgatctccct ctatggcccc tatccccata agtgttgtta
    12601 ccaccggtat accgcacttt tcagcaaaag aggtcattat atctgtggct tctgcagtca
    12661 caacaccgcc gccggcacaa ataaccggtg ttttggattt tgagattgct tcggcaattc
    12721 tttttatctg ctggggatgt cccttgtaat ttggtttata gccttttatt tccactattt
    12781 ccggatagtt aaaatccagc ttttgtgtct gtatatccac cggaacatcg attaccaccg
    12841 gtccgggcct tcctgttgaa gctatgtgaa aggcttcttt aataatcctc ggcagctccc
    12901 gtacatcctt tacgagatag ttgtgcttgc agaagggtgc tgttgctccc gttgtatcaa
    12961 cctcctgaaa aacatccctt ccgatcagtt ccagggatac ctgccctgtg atagcaacca
    13021 tgggtatgga gtcggaatat gcggtggcta ttcccgttat cagattcgtg gccccgggcc
    13081 ctgaggttgc cacacagaca ccgggcttgc ctgtaaccct tgcaaacccg ctggcagaat
    13141 gagcagcacc ctgttcattt ctggtcagca catgtgttat ttccgaatcc agcagagcat
    13201 cataaaatgg acagattgct gctcccggat aaccaaatat tatatttatt ccttcaagtt
    13261 ccaatgcttt taccatagcc tgtgcacctg tcagcttcat tcccggtcct ccttctatta
    13321 atacttcttt cattattacc caaagttacc caaagttact cccaacacac cacccggtat
    13381 caatatttga tcccggccaa cccccggaat gatgttatgg cgattttaaa atgagattta
    13441 gatataaaaa taccctcggc tctgcaatat gcagggacga gggataattc ctccgtggta
    13501 ccaccctgat ttaatgcaat ctataaaaag actgcactct cagtggacat ctccggcgcg
    13561 cgcctgtgtc cgggctatat cgtagccgcc gctgccgcct accgtgataa aatatcattt
    13621 tggcagcagt cctccggaac gagttataca tgtacctgtc gtatcagctc gcaccatccg
    13681 ctgactctct gacccgaatt caatacatct tacttccttc atcgatcaat taatttaatt
    13741 gtctcttttc agtccataaa aaacttgaaa aagctgtaaa tcctatattt gaaataatta
    13801 tagcatctat tttttttacc gtcaacaaca cacccttaat gttttctgac cagtttcaag
    13861 tacctttttc atgttttata tcatattgct ataaattatt ttgaagtttt tcttttctta
    13921 cactctctta cattataata tatatttcat ttgcaatttt cactaatata tcagccctgt
    13981 tttgccgata taactaagga aaatgtcagt aaccatgact tttttatcta caaaagcgta
    14041 atttctgaaa aggagaccaa tatctaatga aacgaattct atcaatcatt atggttatag
    14101 cattggtgct tgcaaaccta tctctgaacg ttcagaaggt atttgctgcg tcccccgctc
    14161 ctgcggcagg caatataatc ataaccaaca atctcacagg aaaatcggat actatttaca
    14221 tattcggact tgatcccggt actttggtca aagtatatac ggcctcaacc ggaaataaga
    14281 tcctgaccta tggaacggtc tctaagagca agtccgagat taccttatca gttcctcaaa
    14341 tcggtactga cgagggaagt ctttatatat cggtaattga aaagggaaat accgaaagcg
    14401 gcaggacaaa agccgactac cctgccgagc caaggtccgg tgctatcgat cctaaagccg
    14461 tgacaataac aaataacgct caaaaatcag acgttattta tgtctcaggg cttaccccaa
    14521 gagatgtaat taaagtctac agtgcagaga ccggaggaaa actgctgggc agtaaaactg
    14581 tttccacatc aggttccgat gtcacaataa cagtacctca ggttggcagt gcagaaggct
    14641 ctgtatatgt aacagtaaca agcaaaggct atctggaaag taaaagaaca gaagtccctt
    14701 ttaaagccga gccggcctca gcacctcttg atcctgacaa catagtaata aacaataacg
    14761 ctaaaagtgc cgacaccgtt tatatccccg gcctcagcgc cggcgatgtc gtaaaaatat
    14821 ataacgacag cggcaaggtt ctggcaacta aaactgtggg ttcctcagcc tacgatgcaa
    14881 caatatccgt gcctcagctt ggtgttgacg caggaattgt atacattacc gtcacaagca
    14941 aggagcttgc tgaaagttcg tcggtaccag tagaatttga aggtgagctg gcttccgaaa
    15001 aaccgaattc aggatttatc accgttacca acaactcggg aaaagctgac acggtatacg
    15061 ttaccggact gtccccaagc gatgttgtaa aggtatacaa taaagaaacc aaaggtagtt
    15121 tgcttggcca ggcaacagta acttcctcag gaaatgaagc cacagtatca atacctcagt
    15181 tgggttcttc ctcaggtgta gtttatgtaa ctgttaccaa tgccggaagg aatgagagcc
    15241 aaagagtcaa aatcagctac tcgcaggaag gctcttctac agatatagct ccgtccaata
    15301 taactgtcac caacaatgtg ggcaaagccg ataccgtata tgtttccggc cttgtaagcg
    15361 gcgatgtggt caaggtgtat gatgcagaat acacaggaaa tctgctggga agtgcaacgg
    15421 ttgccaaatc agctaccgat gtcaccatat caatttcaca gcttggaact gatagtggtt
    15481 cggtttacgt atccattaca acctcgggga aactggaaag ctccagagtc ccggcagagt
    15541 accttgcaga gtcaaaatcc aattcgctgg attcaaactc ggtaactgta accaataatt
    15601 ccggagcggc tgacacaata tatgtcaccg gtttaacaga gggtaccttg atcaaggttt
    15661 acaatgcgcc agcctcagga tctctgttgg gttctgcgac ggttgcaacc tcaaagaccg
    15721 atgcgacagt gactatttca cagcttggta ttgccggagg ctcggtttat ttaacgatca
    15781 cccagcccgg tgcccaggaa agcggcagga cgaaaatcga ttacagtgcc gaaggaactt
    15841 cgacagagcc aaatattaac aatatttcaa tatcaaacaa tgttggaaaa gcagatacta
    15901 tatatgtaag caaccttact ccgggagata ttgtaagaat ctataacgca ccttcgcagg
    15961 gcaacatcat cggaactgcc actgtagcaa gctcagcggc agatgttacg gtaagcatag
    16021 cacagcttgg cacagcagca ggcagtgtat atgtaaccgt aaccagcacc ggaaaagctg
    16081 aaagcaaaag aaccaaagca gactacaagg cagagagtgt ctatgtcgat gtggattcct
    16141 ccaacatcac tgtgacaaac aatgcaggca aagccgacac tgtttacttt acaagattat
    16201 ccgcaggaga tgtggtaaaa gtatatgatt ccctgcaggg aggtacactt ctgggatcag
    16261 caacggtagc agccggatca accgatacta ctgtcagcat tccgcagttg ggcaagggtg
    16321 ccggaagcgt atttgtaacc gtatccagca ccgataaatc ggaaagtgcc agaaaagaag
    16381 tgacttacac cggagaagct tcatctgttg atttgagtga atctcaaata gttgttacaa
    16441 ataatatatc gggtacacct gataccatct atgtctcagg cttgagtccc gaagatgttg
    16501 tcaaggccta cagtgcccag aatcagggaa tcctcctggg aagtgcaaca gttcctgcag
    16561 caggtacaga tgctactata accgtaacac agcttggatc tgccaagggc tctgtttata
    16621 taactgtaac aagctcaggc aagctggaaa gcaacaggac caaagcggat tattccgacg
    16681 agggtaaatc tactgagcct gatagtaata acattactat aaataataat tcgggtgctg
    16741 ccgatactgt cagagtcacc ggcctgacag caggagatgt ggtcagggtt tattccgccg
    16801 aaacaggagg aaacctgctc ggttcggcaa ccgtgacaac ctatagctct gaagccacag
    16861 taacaataac acagctgggt accgcagccg gtaaagtata tgtcacggtt gcaggcacaa
    16921 acaaggctga gagtaagaga attaccgccg actacgatgc cgagcctgtt tcaggcaaac
    16981 tggacagttc ccgcatcaca gttactaata atgccggttc tgccgatacc gtaagggtta
    17041 caggtctgac accgggcgac gtggttaaag tgtactccct gtcttcaggc ggcaacctgt
    17101 tgggttcagc cacagtagcg gcttcaagta ctgaagcaac tgtggagata gcacagctgg
    17161 gcactgccga aggtaaagta tatgtgactg taacaagtgt gaataaagct gaaggagaga
    17221 gaacagacgc ggcatacaag gccgaggaag cctccacttc tcccgatcct gcaaaagtgt
    17281 cggttgccaa caattacggt atagccagta caataacagt aggcggatta aaggataatg
    17341 atgttgtaag catatacagc gctgaatcag gcggaaccct gctgggtaaa gggactgtag
    17401 ccacctacaa ttcagaggtc accatatcgg tttcacaatt gagcgatacc ggaggagatg
    17461 tttatatcac ggtaaccact cccggaaagc tggaaagtaa tagagccaag gtcacctatg
    17521 aggcgaaggc ggcatcaact cctcctgatg catccaatgt agaaatatac aataatgttg
    17581 gctttgccga taccataacc gtattcggaa tggaacccaa tgcagtaatc aaagtataca
    17641 cccaggctac cggcggtaat cctatcggca ctgctacagt tccggccgac agtaccgagg
    17701 ctactatttc aataactcag ctgggcgtaa acgacggagt tgtttatatt tcggtaacga
    17761 ccaaaggaaa aaccgagagc ggcagagccg ccatctccta cacaaaggag agcgcttcgg
    17821 agccccttgc tgccggcaat gtcaaaataa caaataattc cggcatgtcg gacacaatag
    17881 tcgttaccgg gcttctggca tatgatacca ttaagattta caattccgaa accgacggta
    17941 cgagacttgc aacggcagtt gcagatgaga atactctggc ggctgcggcc aatatatcac
    18001 agctgggtac cggtgcaggt aagatttata ttaccgttac caactacggc aggagtgaaa
    18061 gtgccagaac cgcagtggaa tacgaggccg aatcgacggc acctctggca tccaacatat
    18121 tcattgtgaa taatgctggt atagccgata caataactgt gaagggatta aatgataccg
    18181 atgttgtcaa ggtatatgat gccgcttcca acggaaacct cataggcgcc gccacggttc
    18241 ctcccggaag cagtatggca accatgtcgg tgacacagct tacctcagca gcaggaaaag
    18301 tttatgtatc agtgacaaat tacggcaggg cagaaagcag tctgacaaaa gccgaatata
    18361 tatccgaaac aagcactatg gcaccatata tcggagatat ttacatagtt aataatgtag
    18421 acattaatga tactattacc gtatataatc tgttatccgg tgacgttgta aaggtttatg
    18481 acagtgctgt cggcggaaac ctgctgggta atgcgtcggt tgccaataat aagaccgaag
    18541 caacggtatc tgttgaggac ctcggctcgg ctgccgggac tgtatatgtc tcagttatta
    18601 caaagggtaa gactgaaagc gtcagaacag aggcgggtta tgttgctgag agcaggtcaa
    18661 ccgcaccgta tgcaggcaat atttacataa caaataatgt gactttgtcg gatataatcc
    18721 aggtatcggg tctgacagcc ggtgacaagg tcaaggttta tgattcggaa tccggcggag
    18781 agcttctggg atcggcaaca gcctcttccg gaagtgatca ggtaaaaatc acagttaagc
    18841 agttgggtga gtcggcaggc agtgtatatg tttcagtaac ttcaaagggt aagacagaga
    18901 gtaagagaac cgaagccgaa tacgtttcgg agcagacaac caatgaaccc tacgcaggtt
    18961 acataagcgt aagcaataat ccaaccggta cttcggatac ggtaaccgta acaaacctta
    19021 acggcggaga tattatcaat gtttactctg ctgctgcagg cggaagcctt ctcggttcag
    19081 ccaccgtagc ctcgggcagc acaacgggaa ccgttgtaat ctcccagctg ggaacagcct
    19141 caggcagtgt gtatatcagt attaccagcg caggaaaggc tgaaagcaac agaaccaaag
    19201 ctgattatcc ggctgagtaa gaccggagtt tgttttaatt aatatgcata aagacacaaa
    19261 aagcgtttca aaccctttgt cggtttgaaa cgcttttgtt ttattatctg tctacatact
    19321 cagtatttca aaaaactgtc cttcactgat atagtttgat tccctgtaaa gaactccctc
    19381 tttgtagaat ctcacgtacg ggatggtatc attccccagc cggttttcct tgaaatttct
    19441 gaactcatca aagaagtccg ttttattgta ttccagttca tatatatcaa tgtcttccct
    19501 ggtgtcatgc ccataaagcc agcctctcat atcatgccat tgggggcacc agtcctgggt
    19561 aagaataata acaaccctgg gctttgaagt aagtatatca tttccgaatt ctccggtttc
    19621 aattgccctc acggcctgtt cccttgtaat aagcttcctg tttatcataa gtataccatc
    19681 ctgtccatgc ggtttttatt ttatatttct ttataggtaa tgtatttata ccctctttat
    19741 tcatgcaata tactttatct ttacttttgt ctcaattcca caaaaaactt tttgagtaat
    19801 tctgtacact gttcgtgaag cagtcctata accacatcga ctctgtgatt gaaccgggga
    19861 attctgaaaa ggtccaccac agaacctgcc gcccctgccc tgttgtccat ggcacctata
    19921 tagagagttc tgattctgga ctgaatgaca gctcctgcac acattgggca gggctccagt
    19981 gttacataca tatcacagcc atccagcctc catgtgccaa gtttttttgc cgcttttttt
    20041 atggcttcta tttcggcatg tgaagttaca tcaagccggg cttccttttt attatgccct
    20101 cttgatatta tcactccgtc cttgacgatg accgctccaa cggcagcctc accttttgaa
    20161 aaagccaatt cggcctgtct taatgcctta agcatgaatt gttcgtttct ggtatacata
    20221 gtggaacctt tctatgttgt ttattgatat attaccctct gttgacaatt tacaacacgc
    20281 ctcacgtggg ctattttgcc gcttttctac gaagtttttt tctataccac tttttccaaa
    20341 aagctctcca gctcctccag ccggaccttt tccctgagtg ttttatctct tgatacaact
    20401 tctacctctc cctgctccag atttctgctg ctgactatca atctcagcgg tattccaaga
    20461 agatctgcat ctgcaaattg aatgcccgcc tgcacgtccc tgtcatccat gataacttca
    20521 tacctgcggg aaagtttgtc atacatttca aaaccagttt tcctgacatc atcatttttc
    20581 ttatttatca tgcatatgtg tatctgccag ggagctatac tcttcggcca gatagggccg
    20641 cagtcgtcat ggtgtgcctc aattatacag gccaaaagtc ttcctattcc aatgccatag
    20701 cagcccatga ccgggtgtct ctgtctgccg tcattgtcgg tataggccat gttcatgctt
    20761 tctgtgtatt tggtacccag ctggaatatg ttgcccacct cgatgccgcg cttcaccgag
    20821 agcctgcctc cgcacttaat acaggtatcc ccttcattga cctttgcaac ttccacataa
    20881 ctctcaggtc tgatatccct ttctacatta atgcctatta aatgataatc agctttgttt
    20941 gcacctgtta ccatattgaa ttggccctta agggattcat cgaagagaat tgtattgttc
    21001 tttgtgtcaa ttccccgggt tcctataaaa ccaaagcaga ttccgcaatt gccgtccaca
    21061 cgttcatcat atggaaatac atttgccttt accacccttt taagctttgc ctcattcacc
    21121 tgcaaatctc ctcgtatgaa cacaatcaga ggctttttac tgttttcaac tgaaaatacc
    21181 gtggctttta taagctttgc agcttctact ttcagaaacc ggcatatatc atctatactt
    21241 ttcatgtcag gagtataaac ctcttctatt tgctgatcca ttccggcatc cccggctgtt
    21301 tggctgtctt caccgctcct gcaaactgtt tttgaagctg ccacctccat atttgctcta
    21361 tagtcacagc tgtcacagac tatgatggag tcttctcccg actcagccag cagcatgtat
    21421 tcatgtgcca catttcctcc catcattccc gtgtcggatg caacggaaac cacctgcgga
    21481 aggccggctc tctcaaatat tttatgatag gagtcgaata ccttgttata gtaaagctcc
    21541 agatcttcct gggaagtgtg aaaggaatag gcatccttca tggtaaattc cctgacgcgt
    21601 ataagtccgc ctctggatct gggttcatca cggaacttgg tctgaatctg atatatcata
    21661 aacgggtatt ttgcataggt cattgcctca cttcttgcca gatgaaccgc cgcttcctca
    21721 tgggtcatcc ccagcagcat atcccggccc gatctgtcct tcatacgcat cagctcactg
    21781 ccgatgcttt caaaccttcc ggactcctgc catagttcag ccggcaatac aaccggaaag
    21841 agcacctcct gaccatcgat tctatccatc tcttccctga ttatattctc aattttcctt
    21901 gaaattcttc tggcaggcat aagcatcgaa tatatcccgt ttgcaacctg gcgcacatac
    21961 ccgcccctca gcaggaatac atgacttata atacttgcct ctcccggttt ttccttcagc
    22021 ctttctccta aaagtctgct taataacata gaaacaatcc tttcctaaaa gtaatttaaa
    22081 agacaaaaat cgctgtacat aagctgtaca gcgatggtta ttttactgat caagcacccc
    22141 gcactgcccg gtttcaaatt ctcttgtgac ttaagaaatt gatatcgcag ataaagcact
    22201 tgcaccttat gaaattcaag atgcaaatgc taacctgggc acgggcagct atttattttt
    22261 aaaaaatcaa tcaatatcat aaaatcctca ttaaaaacat atcatcgtat aattttatac
    22321 cagtttatca ccggtgcaaa attatagcaa gccctaaaag ctttttaaac tcccttcagc
    22381 tgtttccttt tgctcatcac aagcgccacc gatgttatgg ctaccgcaaa gccaagctct
    22441 atcaacatgt atgagattat agggcccata ttgtcaaaat tgaagttggt caaattgctt
    22501 gctgccttat tagccttgat ataccaatac gtaggtataa attttgctat agaaagtaca
    22561 ttttccccca gaaactcctg cggcacaaac actccggtca aaaagcacat tccaagggat
    22621 aaaatgttgg aaacacctga ttgggcattt ctgctcctaa tcaggatacc tacaagaaaa
    22681 ctcatactta gtatcgtaaa tgtcagcacc agagagttta tacaaaaaaa taacgcattc
    22741 attttaaaca tatcctgtct gtataatata acgcttatta taaccagtaa tgcccagagc
    22801 gaaactgaga aaacaatgtt gcccagaaga atttgcatat tcaccgaagt attgcttaaa
    22861 ggtgaacaca ggtttctcct cttgagcttt acatcattaa ataccatcat tatagagctt
    22921 acacccagta caataatatt gatcaaaaca tagggcataa agttgtaaaa ggatctggca
    22981 gcgctggcat cttctgcctt gccctcaaac accttcatct ccacatctgt ctcaacagcc
    23041 agatccttgc cgacctgttt aaccagttcc tcctgtgtaa tgcccttata attattaata
    23101 tatagtctgg ccgtattcag gtatttattc accaatatgt cggtataaat accgcttatg
    23161 gagcctgaaa cagttgtttt atcaattccc acagccttcc ccgacatgaa atcctttgtg
    23221 aaatcagcag gtattccggc tatatactca acttccctaa agaacaaagc atcctgtaat
    23281 tcaactgtat tgttaccaag
//
