LOCUS       c00121_NZ_LNAM..       15276 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LNAM01000155.1 Acetivibrio ethanolgignens strain ACET-33324
            ACET-33324.Scaf31, whole genome shotgun sequence.
ACCESSION   NZ_LNAM01000155
VERSION     NZ_LNAM01000155
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:34:22
            Original ID  :: NZ_LNAM01000155.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 19355
            Orig. end    :: 34631
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15276
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[29355:34460]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15105
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15276
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15276
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             103..591
                     /locus_tag="ctg121_19"
                     /transl_table=11
                     /translation="MKREVQVYYGSGKGKTTAAVGHCIREASLGHQVIIIQFLKGRNAD
                     ELGFLVKLEPDIKLFRFEKEEAFYLDLPEDKKLEEKKNILNGLNFAKKVIETGECDFLV
                     LDEILGLIDLGIITEDELISLIELRNDPYKLLLTGQNLSPRLLEYVDVAAEIRQVKGE"
     CDS             793..1815
                     /locus_tag="ctg121_20"
                     /transl_table=11
                     /translation="MECYLKKLKNRISISLGADISRLFLCLEPYFYRRPVYYFIIWEEK
                     NMAIFKGAGVALVTPMNEDGSVNFEKLEELVELHIANGTDAIIACGTTGESATLPIEEH
                     LEVIRVCIEVAKKRIPIIAGAGSNSTSSAIYTSTQSEKLGADGLLLVTPYYNKATQNGL
                     IAHFTTIANSVKIPAILYNVGSRTGVNMAAATTAKLVKTVDNIVGIKEASGNISQVAEI
                     MSLTDGNIDLYSGNDDQIVPILSLGGIGVISVLSNVAPRDTHDIVAKYLAGDVEGSRKL
                     QLKYIPLIKALFSEVNPIPVKKAMSLMGMDTGVLRLPLTEMEPEHAAVLETELRNTGLL
                     "
     CDS             1866..2606
                     /locus_tag="ctg121_21"
                     /transl_table=11
                     /translation="MHGCNGAMGQTITRLVREDENAEIVAGIDTRNTIDNGYPVFQSLR
                     RCDVKADVIIDFSSALAVDSLLDNGIAKQLPIVLCTTGLSEEQLKKVKMSSGMIPILRS
                     ANMSLGINMLMKLLQDAVRTLEPAGFDVEIVEKHHNQKIDAPSGTALALADSINAAMND
                     QYEYVYDRSQVRQKRQKKELGISAVRGGTIVGEHEVIFAGTDEVIEFKHTAYSKAVFAK
                     GAVAAAKFLAGRRPGLYDMSDVIR"
     CDS             2799..4883
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg121_22"
                     /sec_met_domain="PTS_EIIC (E-value: 1.3e-94, bitscore:
                     307.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDKIFGILQRVGRSFMLPIAILPVAGLLLGIGGSMTNETMLTTY
                     GLLGLLGPGTAFHAIFEVMSEAGNIVFANLPIIFALGVAIGMAKKEKEVAALAAAIAFF
                     IMHASISAMITIHGGAEQMLAGATASVCGITSLQMGVFGGIIVGLGVAALHNRYYKIEL
                     PQVLSFFGGTRFVPIICSLVYTAVGIAMFFLWPVVQNGIYAVGDVVLNSGYAGTWVYGL
                     MERLLIPFGLHHVFYLPFWQTAVGGTLEVGGQMVEGAQNIFFAQLADPSVEHFAVSATR
                     FMSGKFPLMIFGLPGAALAMYHTAKPEKRQAVGGLLMSAALTSMLTGITEPLEFTFLFV
                     APLLYGIHCVMAGLAYMLMHVFQVAVGMTFSGGLIDLFLFGILQGNAKTNWIWVAIVGI
                     GYFTVYYFLFRLLIVKLDLKTPGREDSEEVKLYRRSDVEEKKKGQKTEEKDALSAAICR
                     GLGGKKNISDVDCCATRLRCTVKDSALVEDRVLKGTGASGVVHKGNGVQIIYGPRVSVI
                     KSNLEDYLETAPEKVEIKEERKLVRTEIISSPITGTAMDLSKTPDEAFAGRMMGDGAAV
                     APEDAVVRAPEDGEVCFIFDTKHAIGFETAAGIGLLIHLGIDTVKLGGSGFEVLVEGGQ
                     KVEKGTPLIKMDLEYLKQNAPSLVSPVICTELGDNEKVRLLKEGTVQAGESLFAVDFYE
                     "
     CDS             4931..5773
                     /locus_tag="ctg121_23"
                     /transl_table=11
                     /translation="MYRVTKVLNHNAVIVVSDDNQQEYMIMGKGAGFGKRVGEQIELRQ
                     QDIVYSLQESTERGAVKELVKSITPVYLEIAAELLEEAKKTFGKIDQRILFPLADHLEF
                     AVARIRKGEQISNPLTEDIRVLFPEEFKTAKSAGGILKNRLQAEISEDEIGYIALHIHS
                     AIEDDKVSEAMQMARAVRECISLIEGEGGLTIQTASLSYNRLMNHIRYMIARAVSGEQL
                     KVNMNDYMGVRFPKAFQMAENVCDEIARNLKCELSEEEIGYLAMHIERVLSDEEKALR"
     CDS             5776..6576
                     /locus_tag="ctg121_24"
                     /transl_table=11
                     /translation="VKMVILFLDRMTIYVMIEVDFTGYGKSERRQSMYEFVDLRDVVKE
                     YHMGEVSIKAVNGINFQIKEGEFVVIVGPSGAGKTTVLNILGGMDSATFGQIIVGGQDI
                     GKFNEKQLTSYRRDDIGFVFQFYNLVQNLTAKENVELALQICKNPREAEEVLTEVGLGE
                     RLDNFPSQLSGGEQQRVAIARALAKNPKLLLCDEPTGALDYNTGKQILKLLQDTCRERK
                     MTVIVITHNSAIAPMADRVIKIKNGTVSKVTENIEPMSVEDIEW"
     CDS             6592..9882
                     /locus_tag="ctg121_25"
                     /transl_table=11
                     /translation="MKTKALRKEFYMEIKKTYNRFLSIFLIVALGVAFFSGIRASEPDM
                     ELSADKFYDENNYMDIRVLSTLGLTKEDVSALKAVKGVEAVVPSYSTDVLSFREDGMYT
                     LKVFSVSEQLNEITPIKGRLPEKSGECILDSGLEEFGYKLGDRITIESGTEAAISDSFA
                     VTEYTVVGMGITPAYLSVQRESSRIGRGYVDGFMAVPEEDFDMEAYTEIYLSVAGAKEL
                     VSYRADYQDLVDGVIDAVRVIQPERENARYQEVKTEADEKIADAEKELADGKKEAEEKL
                     LDGYKKITDAKQELSDGKKEIADGKKEIAENKKKLTDAQKEIDAGEKKLADGKKNYEKG
                     KKELEVNKLELKEKKAELLKGKSKLEAGKKELETKKEELKAQEVQFEQAKAAGLLDEAT
                     VAATQQGLEAGKQQLAAAEAELSKSEKEILAGERQLSEGEKQLAAGERELAKAKETLEA
                     SEKELSKGQKEIDKGLRELAKAEKEIKDGEKELLEGEEELAEKEAKYWEEKAKADKEIA
                     DAEEELSDAKRELADLEMPKWYVLGREYSQVYTEFGQNAERIGAIGEVFPVFFFLIAAL
                     VCLTTMTRMVEEERTQIGTLKALGYSRSSIAAKYLLYAGLASLSGGIFGALVGQKILPM
                     VIVNAYRMMYVNLPYCLLPYNMWYSVTSIAIVMACTVLAAYFACMKELRTNAAQLMRPE
                     APKAGKRVLLERMEFIWRRLSFGQKSSVRNLFRYKKRFFMTIIGIGGCMALLLVGFGVK
                     DSIFNIARFQYEELFHYSGSIIKKEAASEKELSQLYEYLDSNKNIQSYLPVYQTSVNLT
                     AGTTEKNAYLVCPENTGEFGNYIRFRDRLSQEEYALTEDMEGIILTEKMASMLGVGVGD
                     TVTIKLDDTTRADATITYITENYALHYVYLSAGVYEKLFGEYPEFNLLFYETYDSSEIA
                     RDTFAKEVLNYEAASEVQSNAEAKKNVEDMLDSLNVVVYVLIICAGLLAFVVLYNLNNI
                     NINERRRELATLRVLGFYNREVAAYVYRESIMLTGIGIVVGIFLGIVLHRYVILTAEID
                     MLMFGRNINKISFLYSAILTAVFSALINWIMYFKLKKIDMVESLKSIE"
     CDS             10001..11323
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_26"
                     /sec_met_domain="Fer4_10 (E-value: 9.5e-11, bitscore: 32.8,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 6.3e-08, bitscore: 23.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.5e-16, bitscore: 51.1,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 4e-52, bitscore:
                     167.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 7e-38, bitscore: 119.8,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.4e-05, bitscore: 14.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAGTFKGGIHPFEGKDLSKDLPTKVVLPKGDLVYPLSQHIGAPA
                     TPVVAAGDKVLVGQRIGESAGFVSANICSSVSGTVKAIEKRLMVSGAMGDAIVIENDNE
                     YTPIKGLGEERDYTKLTKEEIRQYIKDAGIVGMGGAGFPTHIKLTPKDENAIDYVLVNG
                     AECEPYLTSDYRMMLEEPEKIVGGLKVILRLFDNAKGLICIEDNKPEAIKILTDLVKKE
                     DRVEVKVLKTKYPQGAERQVIYAATGRSINSSMLPADAGCVVNNIDTVISVYMAVCKST
                     PLIRRIVTVTGDAVKTPQNFNVKTGTNYAELIEEAGGFTAEPAKIVSGGPMMGMALFDI
                     NVPVTKTSSALLCLTKDEVAEQEPTACIRCGRCAEVCPSHLIPQKMLEYAEKFDDEGFQ
                     RLYGMECYECGSCTYVCPARRRLTQAFKQTRRSILDSRRKK"
     CDS             11337..12350
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_27"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.8e-117,
                     bitscore: 382.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSNLLNVSASPHVRSQVTTRVIMRDVAIALLPAAAFGVFNFGIKA
                     LITILTCIAASVLSEYIYEKVLHKPITTGDYSAVVTGLLLAMNLPATAPIWMSIIGSVF
                     AIIVVKQLFGGLGQNFMNPALAARCFLLISFTGRMTDFNIKTIEISTSTVDSVVSATAS
                     ATAADALATATPLGVLEGGGAVNVLDMFLGLTKGTIGETSAICILIGAAYLLARRVISF
                     RIPGAYLGAFAVFILIFGGHGLDMNYLAAQLCGGGLLLGAFFMATDYVTSPITPRGQLV
                     FGVLLGILTGIFRIFGGSAEGVSYAIIFCNLLVPLIERVTIPTPFGIRKEAASNAK"
     CDS             12340..12963
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_28"
                     /sec_met_domain="FMN_bind (E-value: 1e-18, bitscore: 58.8,
                     seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNKNTMWKDTLSLFAITLVAGGLLGLVYQVTKEPIALAKYNKKQ
                     EAYKAVYADAASFEENSDLSSAVASAEEALANAGITGVYISEALEARDASGETIGYVMN
                     FGSNEGYGGAVDLSCGIAKDGTLTGLSVLSMSETAGLGAKCTEEAFQAQFAGIKADSIA
                     YTKTGRSADNEIDAIGGATITTTAVTKAVNGALAFIHANGELSK"
     CDS             12938..13732
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_29"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.3e-68, bitscore:
                     221.4, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPMGSSVNNTGGRKLNKYLERLYNGITKENPTFVLMLGMCPTLAV
                     TVSGMNGLGMGLTTTAVLVLSNAMISLLRKVIPDKVRIPAFIVVVASFVTIIQFLLEAY
                     IPALNEALGLYIPLIVVNCIILGRAEAYASRNGVLLSIFDGLGMGFGFTVGLTCIGIVR
                     ELIGSGKIFGFGLMPASYEPATIFVLAPGAFFVLALLTALQNKFKAPSATNATGDVAIA
                     CGGNCASCSGTACAANHGILEAERAAKKAETLRALKERRSNS"
     CDS             13729..14304
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_30"
                     /sec_met_domain="Rnf-Nqr (E-value: 7.3e-65, bitscore:
                     209.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKELIIILIASALVNNVVLSQFLGICPFLGVSKRVETAAGMGAAV
                     LFVITIASAVTYLIYAFVLEKLDVTYLQTIVFILVIAALVQFVEMVLKKLMPALYSALG
                     VYLPLITTNCAVLGVAINNVKKEYTFLESMANGIGTSIGFLISIVIMAGIRERIEDNDI
                     PNVMKGSPIVLVTAGLMAIAFCGFAGLL"
     CDS             14320..15105
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1020:4Fe-4S binding domain (Score: 29.7; E-value:
                     1.2e-09)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_31"
                     /sec_met_domain="Fer4_7 (E-value: 1.6e-10, bitscore: 32.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.4e-10, bitscore: 30.6,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2.8e-17, bitscore: 53.2,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-06, bitscore: 19.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGIVLAALVIGITGVLIGLLLGVAGKIFAVEVDERVVKVREQLP
                     GNNCGGCGFAGCDALAEAIVKGEAPVNGCPVGGPNVAAAIGEIMGSAAGDMEKQVAFVK
                     CNGTCDKTEIKYNYYGIHDCRKLALIPGHGEKKCAYGCMGYGSCVSECNFDAIHIVNGV
                     ALVDKEKCVACGQCIKACPNHLIELVPYGAKHLVRCSSHDKGKDVKAACETGCIGCGIC
                     AKQCEVGAITLENNLAYIDQSKCTKCGKCAEKCPAKIIL"
ORIGIN
        1 ataaggcaaa agaaggcata gcaatttgag tacatctatg gtataatagc cttaagtgat
       61 gtctggtgct ctaataagaa aagcaggcag gaaggtgaga agatgaaaag agaagttcag
      121 gtatattatg gaagcggtaa gggaaagaca actgcagccg tgggacattg catcagggaa
      181 gcgagtcttg gccatcaggt aattattatt cagtttttga aaggaagaaa tgcggatgaa
      241 ctgggattct tagtaaagct ggagcctgat attaaactgt tccggtttga aaaggaggaa
      301 gccttttatc tggatttgcc agaggataaa aaactggaag aaaagaaaaa tattctcaat
      361 ggccttaatt ttgcaaaaaa ggtaatagaa acaggagaat gtgacttttt agtgctggat
      421 gagatcctgg ggcttattga cctggggatt atcacagagg atgagctgat ttcactgatt
      481 gaacttagaa acgatcctta taagcttctg ctaacagggc agaacttatc accaaggttg
      541 ttagagtatg tggatgtagc tgctgagatt cgtcaggtaa agggagaata aatctttggt
      601 tgacaaactg tagcaggaat gatagtatat agaaaattgg tagaggtgca agaagcaaag
      661 agtagatcat tggatatggt tcaggacata gaggaaagtg attgaaaggt gtgattgccg
      721 aagggaaatg gacctgggac attttgcctg gtcatagggc taagagctct atgactgtca
      781 tcatacaatt tgatggagtg ctacctaaag aagctaaaga acaggattag tatatcttta
      841 ggagccgaca taagtcggct ttttctatgc ttagaaccat atttttatag aaggccggtt
      901 tactatttta ttatttggga ggaaaagaat atggcaattt ttaaaggagc aggtgtagcg
      961 ttagtaacac cgatgaatga ggatggaagt gtaaattttg aaaagctgga ggagctggta
     1021 gagcttcata ttgcaaatgg aacagatgct attattgcct gtggaacaac gggagagtca
     1081 gcgactctgc cgattgaaga gcatctggag gtaatccgtg tctgcattga ggtggcaaag
     1141 aaaagaatac cgattattgc aggagcaggc tctaactcta caagcagtgc aatttatacc
     1201 tcaactcagt ctgaaaagct gggagcagac gggcttttac tggtaacacc ttactataat
     1261 aaggctacgc agaatggcct cattgcacac tttacaacga ttgcaaattc tgttaagatt
     1321 ccggctattt tatataatgt aggaagccgt actggtgtaa atatggcggc agctactacg
     1381 gcaaagcttg ttaagacggt ggataatatt gtcggtatca aggaagctag tggaaatatc
     1441 agccaggttg cagaaatcat gagcctgacc gatggaaata tcgatttata ctctggaaat
     1501 gatgaccaga ttgtgcctat tctgtcttta ggaggtattg gtgttatttc cgtgctttct
     1561 aatgtggctc caagggatac tcacgatatt gttgcaaaat atctggctgg tgatgtggaa
     1621 ggaagccgaa agcttcagtt aaagtatatt ccactgatta aggcattatt ctcagaggta
     1681 aacccaatcc cggtaaagaa ggctatgagt ctgatgggaa tggatacagg agttttaaga
     1741 ctgccattga cagaaatgga accggagcat gctgctgttt tagagacaga gcttagaaac
     1801 acaggtcttt tataagagct gggaagcaaa ggaaaagagg gacaaaagaa atgacaagga
     1861 taatcatgca tggctgtaat ggtgccatgg gacagacaat tacccggctg gtgagagagg
     1921 acgaaaatgc tgaaatcgta gccggtattg atacaagaaa tacgatagat aatggctacc
     1981 cggtattcca gagtcttcgc cggtgtgatg ttaaggcaga tgttattatt gatttcagtt
     2041 cagccctagc ggtagattcg ttgctggaca atgggattgc aaagcagctt ccgatagtgt
     2101 tatgtacgac aggcttatct gaggagcagc taaaaaaggt gaaaatgagc tcaggaatga
     2161 taccgatttt aaggtcagca aatatgtcac tgggaattaa tatgcttatg aagcttttgc
     2221 aggatgctgt gagaacgctg gagccagcag gctttgatgt ggaaatcgtt gaaaaacacc
     2281 acaatcagaa aatagatgca ccatctggta ctgccctggc tttagcagat tctatcaatg
     2341 cggctatgaa tgaccagtat gagtatgttt atgaccgcag tcaggtccgc cagaagcgtc
     2401 agaaaaaaga gcttggtatt tctgctgtcc ggggaggaac gattgttggt gaacatgagg
     2461 ttatctttgc cggaaccgat gaagtaattg aatttaagca caccgcctac tccaaagccg
     2521 tgtttgccaa gggtgcggta gcggcagcga agtttttggc aggcagaagg ccgggactgt
     2581 atgatatgag cgatgtaatc cggtaattta caataaaaaa gcttgacaga gtttttttgg
     2641 tatgataagt taattatatg atatagtatg taacttattt gagaatgagg cattaactat
     2701 acataaatat tttaggatgt ttatgtgggc taatgccttt ttttattcga taggaaagtg
     2761 cgtcacatca gcatctgtat aaaaaggaga aagagacgat gaaagacaaa atttttggta
     2821 ttttgcagcg tgtaggaaga tcctttatgc ttccgattgc cattctcccg gttgcagggc
     2881 ttttactggg aattggcggt tctatgacaa atgaaaccat gcttaccacc tatgggcttt
     2941 tggggctttt aggaccgggc acggcattcc atgcaatttt tgaggtaatg agtgaggcag
     3001 gaaatattgt atttgccaat cttccgatta tttttgcctt gggcgttgct attggtatgg
     3061 caaaaaaaga aaaggaagtg gctgccctgg cagcagcaat cgcctttttt atcatgcatg
     3121 cttctatttc tgccatgata acgattcatg gtggagcaga gcaaatgctg gcaggagcga
     3181 cagcctcagt ctgcggaatc acttccttac agatgggagt gtttggtggt attatagtag
     3241 gacttggcgt agcagcactg cacaacaggt attataaaat agagctgcca caggtattat
     3301 ccttttttgg cggcacccgt tttgttccga ttatctgttc tctggtatat acggcagtag
     3361 gtattgctat gttctttcta tggccggttg ttcagaatgg gatttatgct gtaggagatg
     3421 tggtattaaa ttctggttat gcgggaacct gggtctatgg tcttatggag aggcttttaa
     3481 ttccattcgg actgcatcat gtattttacc tgccattttg gcagactgca gtaggtggta
     3541 cccttgaagt tggtggacag atggttgagg gagctcagaa cattttcttt gctcagctgg
     3601 cagatccatc tgtagagcat tttgcagtat cggcaaccag atttatgtca ggaaaattcc
     3661 cgctgatgat ttttggcctt ccgggagctg ctctggcgat gtatcataca gcaaaaccgg
     3721 aaaaaagaca ggcagtagga ggacttttga tgtctgcagc ccttacctcc atgcttaccg
     3781 gtattacgga gcctctggaa tttacctttt tatttgtcgc accgcttctt tatggaattc
     3841 actgcgttat ggcaggtttg gcttatatgc tgatgcatgt attccaggtt gcagtaggaa
     3901 tgaccttttc cggcgggctg attgatttat tcctgttcgg tattttacag ggaaatgcta
     3961 agacaaactg gatctgggta gcgattgttg gtattggata ttttacagtg tattatttcc
     4021 tgttccggct cctaattgta aaactggatt taaagactcc agggcgagag gacagtgagg
     4081 aagtaaagct gtatcgaaga agtgatgtag aggaaaagaa aaagggccag aagacagaag
     4141 aaaaagatgc tttgtcagcg gcaatctgcc ggggactggg cggtaagaaa aatatttctg
     4201 atgtggactg ctgtgcgacg aggcttcgtt gcaccgtaaa ggattcggca ctggtagagg
     4261 atagggtgct gaagggaaca ggagcttccg gtgttgttca taagggaaat ggagttcaga
     4321 ttatttatgg accgcgggta tctgtgatta aatccaatct ggaggattac ttagagacag
     4381 cacctgagaa ggtggaaatt aaggaagaaa gaaagctggt aagaacggag attatttcca
     4441 gtccaattac cggaacggca atggacttat ccaaaacacc agatgaggcc tttgcaggac
     4501 gcatgatggg agatggtgca gcagtagcac cagaggatgc agttgtaaga gcaccagagg
     4561 atggagaggt gtgcttcatc tttgatacaa agcatgcgat tggctttgaa acagccgcag
     4621 gcatcggcct tttaatccat ttaggcattg atacagtaaa gcttggcggc agtggctttg
     4681 aggtattggt ggaaggcgga cagaaggtag aaaagggaac ccctttaatt aagatggatt
     4741 tggagtatct gaagcagaat gctccttccc tggtttctcc ggttatttgt acagaattgg
     4801 gagataatga aaaggtgcgt ttgctaaagg aaggtacggt tcaggcggga gagagcctgt
     4861 ttgcagttga tttctacgaa taagcagaat aaaatagaag tgaaaaaagg tcagaaacgg
     4921 ggaagagttt atgtacagag taacaaaggt gctgaatcat aatgctgtaa ttgtggttag
     4981 tgatgataat cagcaggaat acatgattat gggaaaggga gccggctttg gaaaaagagt
     5041 cggtgaacag attgagctaa ggcagcagga tatcgtttat tcgctccagg agtctacaga
     5101 gcggggagct gtaaaggagc tggtgaaatc cataacgcct gtttatctgg agattgcagc
     5161 agagctttta gaggaagcaa aaaagacctt tggaaaaatc gatcagagaa tactctttcc
     5221 cctggctgac catctggaat ttgcagtagc ccggattagg aagggagagc agattagcaa
     5281 ccctctgaca gaggatatcc gtgttttgtt tcctgaggaa tttaaaacag caaagtccgc
     5341 cggtgggatt ttgaagaatc gtcttcaggc agagatttca gaggatgaga taggctatat
     5401 tgctctgcat attcattctg ctattgagga tgataaggtt tcagaggcga tgcagatggc
     5461 ccgggcagtt agagaatgta tttctctgat tgaaggggaa ggcggattga caatccagac
     5521 ggcgtccttg tcatataacc gattgatgaa tcatatccgt tatatgattg cgagggctgt
     5581 aagtggagaa cagcttaagg ttaatatgaa tgattatatg ggtgttaggt ttccaaaggc
     5641 atttcagatg gcagagaatg tctgtgacga gattgcaagg aatttgaaat gtgaattaag
     5701 tgaagaagaa atcgggtatc tggcaatgca tatcgaaagg gtgctgagtg acgaagaaaa
     5761 agccctgagg tgagagtgaa aatggtcatt ttgttcttgg acagaatgac catttatgtt
     5821 atgatagagg tagattttac tgggtacgga aaatcagaaa ggaggcaaag catgtatgaa
     5881 tttgttgatt taagagatgt ggtaaaggaa tatcatatgg gagaggtatc aattaaagcc
     5941 gttaatggga ttaattttca gataaaagag ggagaatttg tagttattgt aggaccgagc
     6001 ggtgcaggca agacaacggt tctaaatatt ctgggaggca tggattcggc gacttttgga
     6061 caaattatcg ttggtggcca ggatattgga aaatttaatg aaaagcagct gaccagttac
     6121 cgcagggatg atattggctt tgtgttccag ttttacaatc tggtacagaa cctgacggca
     6181 aaggaaaatg tggagctggc tctgcagatt tgtaaaaatc cgcgggaggc agaggaggtg
     6241 cttacagagg ttggcttagg agagcgtttg gataattttc cgtcacagct gtccggtggt
     6301 gagcagcagc gtgtggcgat agccagggca ctagccaaaa atccaaagct tcttttatgt
     6361 gatgagccca caggggcact ggactataat acagggaaac agattttaaa gctccttcag
     6421 gatacctgcc gggagcggaa gatgacggtt attgttatta cccataactc ggcgatagca
     6481 ccaatggcag accgggtaat taagattaaa aatggtacgg taagtaaggt aacagagaat
     6541 atagagccga tgtctgttga ggatatcgaa tggtaagagg ataggtaggg aatgaagaca
     6601 aaagcactga gaaaagaatt ttacatggag ataaaaaaga cctacaaccg gtttctgtcc
     6661 atttttctta ttgtagctct aggtgtagcc tttttctctg gaatccgggc ttctgagccg
     6721 gatatggagt tgtctgcaga taagttttat gacgagaata attatatgga tatccgtgtt
     6781 ttaagcacat tgggacttac caaagaggat gtcagtgcac taaaggcggt aaagggtgtt
     6841 gaagcagttg ttccttctta ttcaacggat gtgctttcct tccgggaaga tggaatgtat
     6901 actttaaagg tattttctgt gtcggagcag ctaaatgaga ttacaccaat caaaggaagg
     6961 ttgccggaaa agtccggaga atgtattctg gacagtggct tggaggaatt tggctataag
     7021 ctaggagata ggattacgat agaatcggga acggaggctg ctatttcgga cagctttgct
     7081 gtgacagagt acacggttgt cggtatggga attacaccgg catatctttc tgtacaaaga
     7141 gagagcagcc ggattggcag aggctatgta gatggcttta tggcggttcc ggaagaggac
     7201 tttgacatgg aggcctatac ggaaatctat ctttctgtgg ctggggcaaa ggagcttgta
     7261 agctaccggg cggattatca ggatctggta gatggtgtaa ttgatgctgt tcgggtcata
     7321 cagccagagc gggagaatgc caggtaccag gaggtaaaaa cagaggcaga tgaaaaaata
     7381 gcagatgcag aaaaagagct ggctgatggt aaaaaagagg ccgaggaaaa gcttttggat
     7441 ggttataaaa agataaccga tgcaaagcag gagctttccg atggaaagaa agaaatcgct
     7501 gacggcaaaa aagaaattgc agagaataaa aagaagctta cagatgccca gaaagaaatc
     7561 gatgccggcg aaaaaaagct ggctgatggt aaaaagaatt atgagaaggg aaaaaaggag
     7621 ctggaggtaa ataagcttga actgaaagaa aagaaagcag agcttttgaa gggaaagagt
     7681 aagctggagg ctggtaaaaa ggagctggag acaaaaaaag aagagctgaa ggctcaggaa
     7741 gtacagtttg aacaggcaaa ggctgcagga cttttagatg aggcgacagt tgcggctacc
     7801 cagcagggcc tggaagcagg aaagcagcag ctggcagcag cagaggctga gctttctaaa
     7861 tcagaaaagg aaattttagc tggtgagagg cagctttcgg aaggcgaaaa gcagctggct
     7921 gctggtgaaa gggagcttgc taaggcgaag gagactctgg aagcctctga aaaagagctt
     7981 tccaagggac aaaaggagat tgataaggga ctcagagagc ttgccaaggc agagaaggaa
     8041 ataaaagatg gagagaagga gcttttagag ggcgaggaag agcttgctga aaaggaagca
     8101 aaatactggg aagaaaaagc aaaggcagat aaggaaatag cagatgccga agaggagctt
     8161 tctgatgcaa agagggagct ggcagatctg gaaatgccaa agtggtatgt actgggtagg
     8221 gagtattccc aggtatatac agaatttggg cagaatgcag agcgaattgg agcgattgga
     8281 gaggtgttcc ctgtattttt cttcctgata gcagccttgg tttgcctgac tactatgacc
     8341 cgtatggtag aggaggagag aactcagatt ggcaccttaa aggcactggg ctacagccgg
     8401 agctcgattg ctgccaaata tcttttatat gcaggacttg ccagtttaag tggcggtatt
     8461 tttggagctt tggttggaca aaagatatta ccgatggtta ttgtaaacgc ttaccggatg
     8521 atgtatgtaa atcttcccta ctgcctgctt ccatataata tgtggtacag tgtgacgtct
     8581 attgcgatag ttatggcatg cacagtgctg gcagcttatt ttgcttgtat gaaagagctt
     8641 cgtacgaatg cggcccagct gatgaggccg gaggctccaa aggcaggtaa gcgggtgctt
     8701 ttagagcgga tggagtttat ctggaggcgg ctgtcctttg gacaaaaatc cagtgtgcgg
     8761 aaccttttcc gttataagaa gcggttcttt atgactatta ttggaattgg cggttgcatg
     8821 gcattacttt tggttggctt tggcgtaaag gattctattt ttaatatagc aaggtttcag
     8881 tatgaagagc tgttccatta cagcggctct attataaaaa aggaggctgc cagtgaaaaa
     8941 gagctttccc agctgtatga gtatttggat agtaataaaa atatccagag ctatcttccg
     9001 gtgtatcaga cctcggttaa tctgaccgca ggcacaacag aaaaaaatgc ctatctagtg
     9061 tgtccggaaa acacagggga attcggtaac tatatcaggt ttcgtgaccg actttcccaa
     9121 gaggaatatg cactaacaga ggatatggag ggcattatcc tgacagagaa gatggcatcc
     9181 atgctgggtg tcggagttgg agatacggtt acgattaagc tggatgatac gacgcgggca
     9241 gatgcaacaa ttacatatat tacggaaaat tatgcactgc attatgtata cttaagtgca
     9301 ggtgtttatg agaagctgtt cggagaatat ccggaattta accttttatt ttatgagact
     9361 tatgatagct cagaaatagc cagggatacc tttgcaaaag aagtccttaa ttatgaagca
     9421 gcctctgaag tccagtcaaa tgcggaggca aagaagaatg tagaggatat gctggactct
     9481 ttaaatgttg tggtttatgt attgattatt tgtgctggac tccttgcctt tgttgtcctg
     9541 tacaatctta acaatattaa tatcaacgaa agacgccggg agctggcaac cttacgggta
     9601 ctgggctttt ataatcggga ggtggcagct tatgtatacc gggagagtat catgctgacc
     9661 gggatcggta ttgtagtagg tatattttta ggaattgtac tccatcgcta tgttatttta
     9721 acagcagaga ttgatatgct gatgtttggt agaaatatta acaaaatcag cttcctgtac
     9781 agtgcaattc taaccgctgt attttcggcc ctgattaact ggattatgta ttttaagctg
     9841 aaaaagatag atatggtgga atctctgaaa agtattgaat aggcgaaaaa ggtcgttagt
     9901 taaatatcta acgacctttt ctcttgaata gtgcataaaa atacgataga ataaagaggt
     9961 atgaaatttg ggaataagaa cagaagggag acgcgttaaa atgtcagcag gaacatttaa
    10021 agggggcatt catccttttg agggtaaaga tttatcaaag gatctgccca caaaggttgt
    10081 tctgccaaag ggtgatttgg tatatcccct gtcacagcat attggtgctc cggcaactcc
    10141 ggttgtagcc gcgggtgaca aggtattggt aggacagcgt attggtgaaa gtgccggctt
    10201 tgtttcggca aatatctgca gctccgtatc aggaaccgta aaggcaatcg aaaaacgtct
    10261 gatggtgtca ggtgcgatgg gagatgctat tgttatcgaa aatgataatg agtatactcc
    10321 aatcaagggc ctgggcgagg aaagagacta tacaaagctc accaaggagg aaatccgtca
    10381 gtacattaag gatgccggta tcgtaggtat gggtggagca ggtttcccaa cccatattaa
    10441 gctgactccg aaggatgaaa atgccattga ttatgtactg gtaaacggag ctgagtgtga
    10501 gccgtatctg acctccgatt accgtatgat gttagaggag ccggaaaaga ttgttggtgg
    10561 tttaaaggtt attttaagat tatttgataa tgcaaaggga cttatctgta ttgaggataa
    10621 taagccggag gcaattaaga ttttaactga tttggtaaag aaggaagacc gtgtggaggt
    10681 aaaggtatta aaaaccaagt atccacaggg tgcagagcgt caggttattt atgcggcaac
    10741 cggcagaagc attaattctt ctatgctgcc agcagatgca ggctgtgttg taaataatat
    10801 tgataccgta atctctgtat atatggcagt atgtaagtca actccattaa ttcgtagaat
    10861 tgtaacggta acaggagatg ctgtgaagac tcctcagaac tttaatgtta aaacaggaac
    10921 caactatgca gagttaattg aagaggctgg tggttttact gctgagcctg caaaaatcgt
    10981 ttctggtgga cctatgatgg gtatggcatt gtttgacatc aatgtgcctg tgacgaaaac
    11041 aagctccgca cttctctgcc ttacaaagga tgaagtggct gagcaggagc cgacagcatg
    11101 cattcgttgc ggacgttgtg cagaggtctg tccaagccat ttgattccgc agaaaatgct
    11161 ggaatatgca gaaaaatttg atgatgaagg cttccagagg ctttacggta tggaatgcta
    11221 tgagtgtggc agctgtacct atgtatgtcc tgccagaaga cgtctgacac aggccttcaa
    11281 gcagacaaga agaagtattc ttgacagcag aagaaagaag taggaggtag agaaaagtga
    11341 gcaatttatt aaacgtatcc gcatctcctc atgtcagaag ccaggtgaca acaagggtta
    11401 tcatgagaga tgttgcgatt gcacttttgc cggctgcagc ctttggagtc tttaatttcg
    11461 gaataaaggc tctgattaca atccttacct gtattgcagc cagtgtatta tcagaataca
    11521 tatatgaaaa agtgttgcat aagccgatta ctaccggaga ttacagtgcc gtagtaaccg
    11581 gacttttgct ggcgatgaac ctgccggcta cagctccaat ctggatgagc attattggca
    11641 gcgtatttgc gattattgtg gtaaagcagc tgtttggtgg attgggacag aactttatga
    11701 acccggcact ggcagccaga tgcttccttt taatttcctt taccggaaga atgacggatt
    11761 ttaatataaa gactatagaa atttccacat caacggtgga ttcagtggta tctgcaacag
    11821 cctctgctac cgctgcagat gctctggcaa cagcaacacc tttaggcgta ttagagggcg
    11881 gtggagctgt taatgtgctg gatatgtttc tgggacttac aaagggtact attggtgaaa
    11941 cctctgcaat ttgcatttta attggagcgg cttatctttt agcgagaagg gtaatttcct
    12001 ttagaattcc gggagcttat cttggagcct ttgctgtttt tatcttgatt tttggagggc
    12061 atggccttga tatgaactac ctggctgcac agctttgtgg tggcgggctt ttgctgggag
    12121 ccttttttat ggcgaccgat tatgttacca gtccgattac accaaggggg cagctggtat
    12181 ttggcgtact gttaggtatc cttaccggca ttttccgtat ttttggtgga agtgcagagg
    12241 gtgtatccta tgccattatt ttctgtaacc tgttagtgcc tctgattgaa agagtgacaa
    12301 ttccgacacc attcggtatc agaaaggagg ctgcaagcaa tgcaaaataa aaatacaatg
    12361 tggaaggaca ccttaagtct ttttgccatt actttagtag ctggcggtct gttgggtctt
    12421 gtttatcagg tgacaaagga gccgattgct ctggcaaaat acaataaaaa gcaggaagcc
    12481 tacaaagcag tctatgcgga tgcagcttct tttgaagaaa atagtgattt aagttctgca
    12541 gtagcttctg cagaggaagc tcttgccaat gcaggtatta ccggtgtgta tatttcagaa
    12601 gctctggaag ccagggatgc ttccggtgaa accattggct acgttatgaa ctttggttcc
    12661 aatgaaggct atggcggggc tgttgattta tcctgcggaa tcgcaaagga tggaaccttg
    12721 accggccttt ccgtgctttc catgagtgaa acagcaggtc tgggagcgaa gtgtacagaa
    12781 gaagccttcc aggcacagtt tgccggaatc aaggctgata gtatagcgta taccaagact
    12841 ggaaggtctg cggataatga aattgatgct atcggtggtg caaccattac aacaacagca
    12901 gttaccaagg ctgtgaatgg agcgttagct tttattcatg ccaatgggga gctcagtaaa
    12961 taacacagga gggagaaagt tgaataagta tttagaacgt ttatataacg gtattaccaa
    13021 agaaaacccg acctttgtcc tgatgctggg tatgtgtccg acattggcgg taacagtttc
    13081 tggtatgaat ggcctgggta tgggtctgac aacgacagcg gtactggtat tatctaatgc
    13141 catgatttcc ctgcttcgta aggtaattcc ggataaggtt cgtattccgg cctttatcgt
    13201 agtagtagca tcctttgtaa caatcattca gttcttatta gaggcatata ttccggcatt
    13261 aaacgaagct ttgggcttat atattcctct gattgtagtt aactgcatca ttttaggccg
    13321 tgcagaggct tatgcttcca ggaatggtgt gcttttatct atctttgatg gtcttggtat
    13381 gggatttggc tttaccgtgg gtcttacctg catcggtatt gtccgcgagc tgattggaag
    13441 cggcaaaatc tttggatttg gtctgatgcc ggccagctat gagcctgcga ctatttttgt
    13501 cctggcacca ggtgctttct ttgttctggc tttgctgacc gcactgcaga acaagtttaa
    13561 ggctccgtct gcgaccaatg caactggtga tgtggcaatt gcctgtggcg gtaactgtgc
    13621 aagctgcagt ggtacagcct gtgcggctaa ccacggtatc ctggaggcag agcgtgcagc
    13681 gaagaaggca gagactctga gggcactaaa ggaaaggagg agtaattcat gaaggagtta
    13741 attattatcc tgattgcatc cgcactggta aataacgtag tattgagcca gtttttaggt
    13801 atctgccctt ttcttggtgt atcaaagaga gtggaaactg cagccggtat gggtgcagca
    13861 gttctattcg ttattacgat tgcatcagca gttacttact taatctatgc ttttgttttg
    13921 gagaagctgg atgttactta tctgcagacg attgtattta ttctggtaat tgcagccctg
    13981 gttcagtttg tggaaatggt tttaaagaag ctgatgccgg cactttacag tgctctgggc
    14041 gtatatctgc cattgattac aacaaactgt gcagtgctcg gtgttgcgat taacaatgtg
    14101 aagaaggagt atactttttt agagagcatg gcaaatggta tcggaaccag tattggtttc
    14161 ttgatttcca ttgttatcat ggctggtatc cgggaacgga ttgaggataa tgacattccg
    14221 aatgttatga agggctctcc gattgtttta gtgacagctg gacttatggc aatcgcattc
    14281 tgcggttttg ccggattatt ataataggag gtcatgaaaa tgaacggaat tgtattagca
    14341 gcactggtaa ttggtattac cggcgttcta attggcctgc ttttaggtgt ggccggcaag
    14401 atttttgcag tcgaggtaga cgaaagagta gtcaaggttc gtgaacagct tccgggcaat
    14461 aactgcggtg gctgtggttt cgcaggctgt gatgctctgg cagaagccat tgttaaaggc
    14521 gaagccccgg taaatggctg tcctgttggt gggccgaatg tagcagcggc tattggagaa
    14581 attatgggct ctgctgctgg tgatatggaa aagcaggtgg cttttgtaaa atgtaatgga
    14641 acctgtgata aaacagaaat caaatataat tattatggaa tccatgactg tcgtaagctg
    14701 gcattgattc cgggacatgg tgagaagaag tgtgcctatg gatgtatggg ctatggctcc
    14761 tgtgtcagtg agtgtaattt tgatgccatc cacattgtaa atggtgttgc gctggtagac
    14821 aaggaaaagt gtgtagcctg tggtcagtgt atcaaggcct gtccaaacca cttaattgag
    14881 ctggtgcctt atggggcaaa gcatctggta cgttgtagct ctcatgacaa gggtaaggat
    14941 gtaaaggcag cctgtgaaac gggatgcatc ggctgtggta tctgtgcaaa gcagtgtgaa
    15001 gtcggtgcga ttaccctgga aaacaatctg gcctatattg atcagagcaa gtgtaccaag
    15061 tgtggtaaat gtgctgagaa gtgccctgca aagattattt tataggaaga tattcagaat
    15121 ggaagaaaag aggaatgcct tgtaacgagg tgctcctctt ttcttccatt ctaaattcag
    15181 ttcctttgtg ttgttaaatg gatggtattt aatctatgta gtgtctgctg attaagcaga
    15241 catttgcaac ttccaactct tacatctgct ccagtc
//
