LOCUS       NZ_LS483427.1          23339 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LS483427.1 Arcanobacterium haemolyticum strain NCTC8452
            chromosome 1, complete sequence.
ACCESSION   NZ_LS483427
VERSION     NZ_LS483427.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:50:16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1690266
            Orig. end    :: 1713605
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23339
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1700266:1703605]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13339
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..23339
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23339
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Pyruvate2acetate-formate"
                     /region_number="3"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             1139..2218
                     /locus_tag="ctg1_1591"
                     /transl_table=11
                     /translation="MKMTFRWYGEGFDPIPLQYIKQIPEMTGIMGTLSGKQAGEVWEDQ
                     EIKDMIAPVHAAGLECEVIESVNVHEDIKMGLATRDEYIANYNTTLENLANNGVKVVVY
                     NFMPVFDWLRTELAHVTDDGSNCLYYDHAEVEGMSPRDIVERTAKDSGGLTLPGWEPER
                     LERLDEVMALYQDIDHEAMRANYRYFLEGIIPTAEKVGIKMACHPDDPAWDLFGLPRIH
                     RNRDDMDKIAKLYDSEYNGFCVCSGSLGSNPDNDVPAIFREFGERGLLNAAHVRNVKYL
                     GEKKFHEAPHPSSTGNLDMHAIMEAIYDTNPDVYIRPDHGRMIWGETGRPGYPLYDRAL
                     GAVYLSGLFESIAKMKSRG"
     CDS             2248..2892
                     /locus_tag="ctg1_1592"
                     /transl_table=11
                     /translation="MAIPSARPFLEKNPIVPVVVLNRVEDAVPTARALLAGGITSAEVT
                     FRTPVAAECIASIARNVPEIAVGAGTVINAEQANAAIDAGATFLVSPGFSATVADVAAE
                     RGVPLLPGVANPTDIMAAVEYGLDVMKFFPAVPLGGLSVIKAFAAPFPQLKFLPTGGIS
                     EKNAAEWLSQPFIAAIGGSWMVTTKLVDNGEFDTITELSAQAMSIAKEVTR"
     CDS             2889..3989
                     /locus_tag="ctg1_1593"
                     /transl_table=11
                     /translation="MTIALRPANECRYDIVSLGEVMLRLDPGEGRIRTARHFAASEGGG
                     EYNVARGSRRAFGRRAAIVTALVRDEVGMLIEDLILQGGVDTSFITWVPSDGVGRSVRN
                     GLNFTERGFGVRGAVGNNDRGNTAVSQMVATDVDWDYLFGTLGVRWLHTGGIFTALSES
                     TAEVAKAAMQAAKKYGTVVSYDLNYRPSLWKSIGGQEKCQEVNRELAQYVDVMIGNEED
                     FTASLGFEVEGANENLDNLEVESFKKMIETVATQFPNFQAIGTTLRQVRSATVNDWGAV
                     AWSREQGFVQAIQRDGLEILDRVGGGDSFASGLIYGLMEFGDIEKAVNYGAAHGALAMT
                     TPGDTSMASLAEVERLVGGGSARVQR"
     CDS             4068..5477
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UxaC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1594"
                     /sec_met_domain="UxaC (E-value: 2.3e-75, bitscore: 251.0,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASPLFLDPDRLFPADEKTRDLARELYTTVKDLPIISPHGHVNPQ
                     MLLDNEPFSDATNLFLTYDHYVFRMLHSAGIDLTKIGVGKSDPVDPRTAWRIFCENWRL
                     LDGTASGYWLTHEFVTLFGIDEEPCAENADKLFDIIAEKLSTPEFRPRALFDSFPISVL
                     ATTDDPLDSLEYHAALAADETFTGQVIPTWRPDAYVNTRKPEWRSKVEALTASVGQPVD
                     SFEGYLEGFRASRARFIENGAVSADFGVAHPLAVDMDDAELGALYHKAVHEGLTAEESD
                     IFEGAMLFRFAGMSVEDGLVMTVHPGVYRNHNTESFTTFGPDTGHDIPVQTEYTKNIQP
                     LLDKYGNDPRLHLVLFTIDETVYSRELAPLAGFYPSVFIGAPWWFIDAPDAVLRFRAAT
                     TETAGFSRSSGFIDDTRAFLSIPARHDMSRRLDSVFLARYVIEGRISRTAAFHWIKALT
                     SDQPRKVFKLD"
     CDS             5636..6643
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LacI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     93.7; E-value: 5.3e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1595"
                     /sec_met_domain="LacI (E-value: 1.6e-15, bitscore: 53.5,
                     seeds: 22, tool: rule-based-clusters)"
                     /sec_met_domain="Peripla_BP_3 (E-value: 1.6e-27, bitscore:
                     93.7, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSKKKTATIYDVASAVGVSPSTVSRAFSNPARVSTDTAERIFAAA
                     RDLGFRTSGAAYASSDKATRVLCLVVADISNPTFAAMYKGFHKAAHEHGYAVVIANSDE
                     SGALEAHTLRRVLPDVDGVALAASRLTPAAILQVEKSKPLVLMNRYLDGHTCVVPDTNG
                     GITAVCRELAERGHKDVMYLSGPEMSWANAMRWRALQDQCAATSLQLTRTKFLSPDLVG
                     GADAARIWNRGRTSAVVAYNDLMAFGFVRQARRLGASIPDDVSVIGVDDSVICHMADPE
                     LSSLSTGSFDIGYKAAMSLIWQAANHTRRERSTIVVPMEFKIRGSIASRGSEKE"
     CDS             6640..9312
                     /locus_tag="ctg1_1596"
                     /transl_table=11
                     /translation="MSLSEPGLNVALDALEDAYGISPSDEAIYDAFASWVESTGKHMYP
                     HQDEALLNIVSGDHVIVATPTGSGKSLIAMQALFAALATGRTAYYTAPLKALVSEKFFE
                     LIRHFGAHNVGMVTGDSSINAGAPIVCATAEILANIALREGASADVGVVVMDEFHFYDD
                     PQRGWAWQVPLLALPQAQQILLSATLGDTRFLVADLERRTGRSVSIVDDAVRPVPLHFT
                     WSTEPIGEVIKELVATHMAPVYVVHFSQKEAVSQALALQSMPIASKEQKERIAAALGSF
                     TFSPGFGKVLSKLLRSGIGIHHAGLLPRYRRLVEKLAQAGLLNVICGTDTLGVGINVPI
                     RTVLMTSLTKFDGTKQRHITAREFHQIAGRAGRAGFDTVGYVVVQAPEHDIENARRLRK
                     AGDDPTKIKRVQRVKAPEGTISWSENTFTTLIEAQPETLTSRMRVDHSLILNLLQRLDP
                     IAGAKTILCDNHEPKKDRNTLVRKAITIYQSLRTAGVITHEDRDWRAQHGDTGAIHFTR
                     DVPSDFALNSPLAPFALAAFDLLEPESATYALDVVSIIEAVSEDPLPALYAQQRQARGE
                     LIGKLKADGVDYDERMALVDEVTWPKPLADLLEPALELYAKTNPWVRGQELKPKSVVRQ
                     LIEEALTFSEFISRYDLSRSEGVLLRYITDVYRAMRQSVPINVRTREVEDIIDWLGRLV
                     RSIDSSLLDEWEALADGRVTLDELTTLGSDDSVHGEEAAFGADADGNVAFTRNKHALRV
                     AVRNAMFERIELLDREDYDALHDLDSAAGWDADTWADAIAPYFDEYDFLGTDNEARSSR
                     FFSILEDPSYADLLQAGMAEDSASDLLESHQTGRVWLALQVLDSGTDDAAWGLWAIIDL
                     DASDAAGTLVVQPIRLGER"
     CDS             9312..10004
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ala_racemase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1597"
                     /sec_met_domain="Ala_racemase_N (E-value: 6e-17, bitscore:
                     58.8, seeds: 314, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAIAESLGRIRDIVDRYAGGRHVDIMLATKHQPIERLIEAYDAG
                     GVLMGHNLVDQLVSANAGLAEHGIHPYTSMIGHVQSNKLSSAMTVADRIDTVDSLKTAQ
                     RINRRQEERVARGEATGPYPVLIQINSAAADTQFGVAIGDVMQLAVAIADLPRVQIRGV
                     MTIGARGSETNIRASFATTRRLSEEMRTLPALADADVISMGMSNDMHLAISEGATVVRV
                     GTAVFGER"
     CDS             complement(10001..10927)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 66.3;
                     E-value: 1.1e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1598"
                     /sec_met_domain="Radical_SAM (E-value: 5.9e-25, bitscore:
                     85.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSIEHQSSDLFDATRYWGSEGSTGEYRPQPIEDEVPRLSGAGL
                     DGVSLAGPMSHHEHVSGVQAGDIGSVHSWELVTAVDGPGTRLTTFFAGCPLRCLYCHNP
                     DTLKMKEGTAVRATDMLEKIARYKAVFTVSKGGVTFSGGEPMMQPKFLARLLAGCKEIG
                     IHTAVDTSGFLGVNMTEEMLANVDLFLLDVKSGVPEQYKRTTGRDLAPTLAFGKRLVEN
                     GKKIWIRFVLVPGLTDAPENVNAVADIVQSWASSVERVEVLPFHQMARDKWASLGLEYQ
                     LNDVEPPSKEATEAVRDIFRSRGLTVF"
     CDS             complement(10951..11199)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1599"
                     /sec_met_domain="Gly_radical (E-value: 4.5e-21, bitscore:
                     72.2, seeds: 99, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATTYEERLESMKAQRAAKGGVQGLYHANINVLNRDTLEDAMEHP
                     EKYPQLTVRVSGYAVNFVRLTREQQLDVISRTFHQGM"
     CDS             complement(11252..13339)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1600"
                     /sec_met_domain="Gly_radical (E-value: 7e-13, bitscore:
                     45.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 4e-260, bitscore:
                     861.1, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTQTAETATHPEWEGFKDGLWQNAIDVRDFIQKNYTPYEGDSSFL
                     AGETDKTRRVWETLEEKYLSVERQKRVYDVDVDTPADVDAFGPGYISEDDNVVVGLQTD
                     VPLKRAMMPNGGWRMVETAIKEAGKEANPEVKKIFTKYRKTHNDGVFDMYTPRIRAARS
                     SHIITGLPDAYGRGRIIGDYRRVALYGVDHLIAEKLKDKDLFADQPFTQDWARDREEIS
                     EQIKALKKLKNMAASYGFDISRPAQTAQEAVQWTYFGYLASVKSQDGAAMSFGRLSAFF
                     DIYFERDLAAGVITEQDAQEIIDQLVIKLRIVRFLRTTAYDEIFSGDPYWATWSDGGFG
                     EDGRPLVTKTSFRLLQTLVNLGPAPEPNITIFWSEKLPMGYKRFCAQVSIETSSIQYEA
                     DEQIRGYWGDDAAIACCVSPMAVGKQMQFFGARVNAAKALLYAMNGGRDEMSGKQIVDG
                     FEGIQGDGPLDFDEVWAKYEDMLDWVVGTYVEALNIIHYSHDKYAYEAMEMALHDSEIV
                     RTMGCGIAGLSIVADSLAAIKYATVTPVRDETGLIVDYKTEGDFPTYGNDDDRADDIAA
                     TIVHTVMEKIKRIPMYRNAIPTQSVLTITSNVVYGKATGNFPSGHRAGTPFAPGANPEN
                     GMDTHGMLASMLSVGKLHYKDALDGISLTNTIVPSSLGRDLAEQVDNLVGIMDAGFIKK
                     G"
     CDS             complement(13607..14755)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1601"
                     /sec_met_domain="Aminotran_4 (E-value: 2.8e-29, bitscore:
                     99.4, seeds: 70, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRSLTSLEQFAQAAWPGADQVAGRFAVASHPNPASQEAYEGAME
                     RLGFGVEFTDHMARGSWTPEQGWHGMRIEPYGPLSLDPAGAVLHYGQEVFEGLKAYRHA
                     DGSVWTFRPAYNAARLNVSNNRLMIPEFPVEDFLGSLAGLVRADERWVPRTPGATLYMR
                     PFIFASEAFLGVRAAHRFEYGVVASPSGPYFTHGFTPIDIWVEREHHRAGPGGMGDVKT
                     GGNYAASFYAKSHAFERGFDEVLFLDAATNTCIDELGAMNVFVVMADGRVRTPALSGTI
                     LPGSTRSAILELLDDDGVAVSEESITLAELWDGIKAGDVAEMFACGTAAAVVAIGSLTQ
                     GDERVVVKHSEFSQSIYRKLTDIQFGVAPDRFGWMYQLAKGE"
     CDS             complement(14820..16265)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1602"
                     /sec_met_domain="Lyase_1 (E-value: 2.2e-95, bitscore:
                     316.4, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 2.8e-17, bitscore:
                     59.7, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVQTRTEEDLLGTREIPDEAYYGVHTQRAIDNFHISGVTINDVPE
                     FIRGMVSVKKAEALANRDKHVLSARVSRAIVDACDLILNDGRCMDQFPVDVFQGGAGTS
                     VNMNTNEVVANLALETLGEPKGKYDVINPNDHVNKSQSTNDAYPTGFRIAVYRMIQQLA
                     EEVDRMRASFAAIGAKNAHVLKMGRTQLQDAVPMTVGQEFDAFGVLMSEEIRNLTRASE
                     LLLEVNLGATAIGTKLNTPDGFQEIVVGRLAEVTGLNVTASPNLIEATSDTGAYISVHG
                     ALKRLAVKLSMICNDLRLLSSGPRAGLNEINLPEMQAGSSIMPAKVNPVIPEVVNQICF
                     KVMGNDTTVMMASEAGQLQLNVMEPVIGQAIFESISLLTRAMVTLRERCVDGITVNEDI
                     CMSYVMNSIGIVTYLNDIIGHHNGDLIGKEAARTGKSVRDIVLERGLMSETELNRTLSV
                     ENLMTPVYMGETFPEESEKEIHD"
     CDS             16492..18093
                     /locus_tag="ctg1_1603"
                     /transl_table=11
                     /translation="MSYLFQLFADNQVLLLFFLVGSGTILSKFRVRGVSLGAAAVLFLS
                     IGITAWALYSGYKIEVEHDLGVLGLALFAFAIGISSGPNFFNTLKSSIVPVLLMLATFA
                     LAGGAAALVGRALGMDWALIAGTFAGATTNTPALSAAGAASGNPALATVGYAIAYLFGV
                     IGMLGFSALALSRRSADQDKPSPICNRTIRVEREDQPTVASLREIIGGTLHFSRIRRGE
                     TGPIWLPADTDVLEKDDLVTVIGTVAEVDQAIKLVGHGSSHSLIANRRYLDFRRITISN
                     SAIAGRKIGELDVEEKFGGTISRIRRGDTDMAASSTIRLQLGDRVRVVAPTHSMSKISK
                     YFGDSSHGLTDINPIALGLGMALGIIIGEWKILTPSGLTFSIGSAAGTLIVGLIMGRLG
                     RIGKFVTTLPFTTCQVLSELGLLIFLAYAGTKAGSQILVAFTGGAWLQILLLGMMVTVI
                     VGGGFYLSMRLFTSTGGTRLAGALGGIQTQPAVLAFANDRTSFDPRVALGYAMVYPVAM
                     VAKIFVGQVLGSFGAM"
     CDS             complement(18219..19544)
                     /locus_tag="ctg1_1604"
                     /transl_table=11
                     /translation="MDHQSTESATSSETIAEKLRSILMLGTMLLACGAGAYRVKAAMAR
                     AAKAIGLTRLDSAVSMTDITATAWNGKESYTSFAEQRRVGVNAEKLDRIMQGVSQLREG
                     MSAADLRLILKETTARDRHYGLWTTVLASAIACAGFCFLNGGRAVECTTVFFAAGIGQL
                     IRKLLLGRGIAHFLIWIVCAVASTLVYITLLAVGSFGGLLYLSQYESGLISSILYLIPG
                     FPLTTAMLDFVRNDVQSALARFSYCLMVIGSAGFSVWIVVHALDWHVEASVVVPLPFWT
                     MTLLRILTSFVAAYGFAVLFNAPWKVCAAAAMAGAFANTGRLLLQNHLHLPWQLGVGLA
                     ALVVGIAATLIAWKTSHSRVSLSVPAVVIMIPGVPFYRGLVALNEGDFQGAIATFAEVF
                     FVIMSIGFGLAIARVLMDNGWRHDMDTSHLPDTLGSDVRDAV"
     CDS             complement(19660..20415)
                     /locus_tag="ctg1_1605"
                     /transl_table=11
                     /translation="MTSLANPFHNAGTSAATYVDVRPGYSRTLLEPLFDDVDGAPCVAD
                     IGAGTGKLTTMLPEIVGLKGSVWAIEPSPDMREQLTNRILDIVRIIDATGEHTTLPDNS
                     CDVVFYAQSWHWVDPRAASAEAARILKPGGKLVILFNQMDVSIPWVKRLTRIMRSGDVH
                     RVTDTPVVVEKFSTPQLTVNVWQDHLTPRNVCKLGTTRSSWITSTPANQERMQANLRWY
                     LHEKLGYEEHHTVEIPYVTYMWVATLPKM"
     CDS             20584..21966
                     /locus_tag="ctg1_1606"
                     /transl_table=11
                     /translation="VTQRPTALRHVLSYGSYAEHLRIGKILRRETTGGIALMIAALVAI
                     IWANSPWAESYTALRDMKLGIDALHLQLSVGHWAADGLLAIFFFLVGLELKQEFVAGDL
                     RSPSRAVVPVVAAVGGVVVPALIYAFFNWNSPETLQGWAIPTATDIAFAVAVLAIIGSH
                     LPSPLRLFLLTLAVVDDLIAITIIAIFYTGEIHGTYFALFLIPAAIFGVLVQRFHVFWV
                     KHRWASWFILFPIAAVAWYFLHEAGIHATIAGVVLGFLVPVAFKHEGAQEALSEHRPDV
                     HGHGDHAPGLISMFEHGIRPISSGFAVPVFAFFSAGVTVGGWDGFVASLSSPVALGILA
                     GLIIGKPLGIVASTFVLTKLTRAKLDDSIAWADMIGVGFLAGIGFTVSLLVGELSFGLG
                     DANNDAAKVGILLASVLAALIAALILVPRNNRYRRIEEAEHADADANGIPDAFERANKE
                     LA"
     CDS             complement(22137..22577)
                     /locus_tag="ctg1_1607"
                     /transl_table=11
                     /translation="MRKLFIAAASYLAVGLISGVFYREFTRAYAYVGDTQLSRIHTHTL
                     VLGTLFFMILIGLNKLFDLSEDKRFNMWFILYNVGLAWTTAAMFTQGVVNIVYGPEEWI
                     PAFSGIAGFGHIILAFGLIRLFQILYTAIRGDSTNADSVLYR"
     CDS             complement(22648..23223)
                     /locus_tag="ctg1_1608"
                     /transl_table=11
                     /translation="MANHLQKHVTNTHASTIQLPTPKPTTETIHPTVLTVVTAVGKRPD
                     PSRTRKLSLPAPMVLHPRECGRVGHRRHHTIEGLTNTPVSPSNTPHNTTTPSPHTWAKS
                     IYNPHQQHAKNDTVVIKQRKTLQQSPYVIKKRHRRQESHIQHSRAISRLFRHRTGLEAV
                     NFGLEVGLEVRIFGPACRGPELIRCFMV"
ORIGIN
        1 taccatgctc acacgatggc gttgatggct ggtttgctgt tccatcgttt tgaggcaggt
       61 ggcgctccga tcaccatgct ttctacggat aacttctccc acaatggcga taagttgcgc
      121 gaatcgatca tgatcgtggc gcgtggttgg gaaggaaacg gcgcagtttc ggccgagttt
      181 attgcgtggc tttcggatga atcgaaggtt gcgttcccga tttcggtgat tgataagatc
      241 acaccgcgtc cgaacgattc ggtttctgcc cagttggcgg agcttggttt ttcggatatg
      301 gatattgagt ttgtgggccg tacgccggtt gcgggttttg tgaatgcgga gcctactgag
      361 tatttgatta ttgaggataa gtttgcgggc gatcgccctc cgttggagga ttacggggtt
      421 cagattgtgg atcgtcaggt gtgtgacgat tttgagaaca tgaaggtcac cacctgtttg
      481 aatccgttgc ataccgcgtt ggctgtaagt ggttgtttgc ttcgtatgcc aacgattgat
      541 tcggagatgc gcgattcggc gttggctgcg atggttcacg agttggggtg gaacgaaggt
      601 ttgcctgtgg ttgtggatcc gggtgtggtt gcgcctgaag atttcttgcg tgaggttctt
      661 gaggttcgtt tcccgaatac gtatcttccg gatgatccgg cacgtatcgc gatggatacg
      721 tctcagaagt tgccgattcg ttttggtgag acgatcaaga agtatattga gcgcgatttg
      781 ccgttggatt cgttgcatac tattccgctt gtttttgcgt tgtggttacg ttatttgacg
      841 gggattgccg acgacggcga ggctttcact ttggcgtctg atcctcttct tgaggagctt
      901 caagggatgt tggctgaagt gtcggttggc atggaactgt ccagcgacga ggctcaccgc
      961 atcgtgcaac ctatcttgtc taacaagcag attttcggtg ttgatttata tacgactccg
     1021 ctagctgcca aggttgaagg ctactttatc gagttggttg ctggcccagg cgctgtacgt
     1081 tccgtgcttg atcgtgaata caccgcctaa aagacgtgac atttttaaag gagatattat
     1141 gaagatgaca ttccgctggt atggcgaagg tttcgatccg atcccgttgc aatacatcaa
     1201 gcagattcct gaaatgacgg gcatcatggg caccttgtcc ggtaagcagg ctggcgaagt
     1261 gtgggaagat caggaaatta aggatatgat cgccccagtt cacgccgctg gcttggagtg
     1321 cgaagttatc gaatctgtga acgttcacga agatatcaag atgggcttgg ctactcgtga
     1381 tgagtacatt gccaactaca acaccaccct tgaaaacttg gcaaacaatg gcgtgaaggt
     1441 tgttgtttac aacttcatgc cagtgttcga ttggttgcgc accgaactcg ctcacgtgac
     1501 tgacgatggt tcgaactgct tgtactacga tcacgctgaa gtcgaaggca tgtctcctcg
     1561 tgacatcgtt gaacgcaccg ctaaggattc cggcggcttg acccttcctg gttgggaacc
     1621 agagcgcctc gaacgcctcg acgaagtgat ggcactctac caagacatcg atcacgaagc
     1681 tatgcgtgct aactaccgtt acttcttgga aggcatcatc ccaaccgctg aaaaggttgg
     1741 catcaagatg gcctgccatc cagacgatcc agcatgggat ctcttcggtt tgccacgtat
     1801 tcaccgcaac cgtgatgata tggataagat cgcgaagctc tacgattcgg aatacaacgg
     1861 tttctgcgtc tgctccggtt cgctcggctc caacccagat aacgatgtgc cagcgatctt
     1921 ccgcgagttt ggcgaacgtg gcttgctcaa cgctgctcac gtccgcaacg tcaagtactt
     1981 gggtgaaaag aagttccatg aagctcccca cccatcctcc accggcaact tggatatgca
     2041 cgccatcatg gaagctatct acgataccaa cccagacgtc tacattcgcc cagatcacgg
     2101 ccgaatgatt tggggcgaaa ccggccgccc aggctacccg ctctacgatc gtgcactcgg
     2161 cgccgtctac ctttctggcc tgtttgaatc catcgccaag atgaagtctc gcggctgatc
     2221 aaccagatgt taaggaatta agagattatg gctatcccat cagctcgtcc atttttagaa
     2281 aagaacccga tcgtccccgt cgtcgtcctc aaccgtgtgg aagacgccgt gcctacggct
     2341 cgtgcgctac tcgcaggcgg aatcactagt gctgaagtga cgttccgtac gccagtggcc
     2401 gccgaatgca tcgccagcat cgcacgcaac gtgccagaaa tcgccgtggg tgcaggaacc
     2461 gtcattaatg cagaacaagc caacgcggca atcgatgcgg gcgcaacctt cctcgtctcc
     2521 cctggcttct cagccactgt ggcagacgtc gctgcagaac gtggcgttcc actcctacca
     2581 ggtgttgcca acccaaccga tatcatggct gcggttgaat acgggctaga cgtgatgaaa
     2641 ttcttccctg ccgtaccact cggtggcctc tcagtaatca aggcgttcgc cgctccattc
     2701 ccacaactga aattcctccc aaccggtgga atctcagaaa agaacgcagc agaatggctc
     2761 agccagccat tcattgcagc aatcggcgga tcctggatgg tcaccacaaa actcgtggat
     2821 aacggcgaat tcgatacgat cacagaactc tctgcacaag ctatgtccat cgccaaggag
     2881 gtaactcgat gaccatcgct ctgcgcccag caaacgaatg ccgttacgat atcgtatcgc
     2941 tcggtgaagt catgcttcgc ctcgatccag gcgaaggccg tatccgcact gcacgccact
     3001 ttgctgcatc cgaaggcggc ggcgaataca acgtcgcacg tggttcgcgc cgtgcattcg
     3061 gccgccgtgc cgccatcgtt acggcgctcg tgcgcgacga agttggcatg ctcatcgagg
     3121 atttgattct ccagggcggc gttgacacgt cgttcatcac gtgggttcca tctgacggcg
     3181 tgggccgaag cgtacgcaac ggcctaaact tcaccgaacg tggattcggc gttcgcggcg
     3241 ctgtaggaaa caacgatcgt ggcaacacgg ccgtttccca gatggttgcc accgatgtcg
     3301 attgggatta tctgttcggc accctcgggg ttcgctggct ccacacaggc ggaatcttca
     3361 ccgctctttc tgaaagcact gctgaagttg ctaaggcagc catgcaggcc gcgaagaagt
     3421 acggcacggt tgtttcatac gatctgaact accgcccatc actttggaag tccattggcg
     3481 gccaagaaaa atgccaagaa gttaaccgtg aacttgcaca gtatgttgac gtgatgatcg
     3541 gcaacgaaga agacttcacc gcttcgctcg gttttgaggt tgaaggggcg aacgaaaacc
     3601 tcgataacct cgaagtcgaa tcgtttaaaa agatgatcga aaccgtggct acgcagttcc
     3661 cgaacttcca ggcaataggc accacactac gccaggtccg ttccgcaacc gtgaacgatt
     3721 ggggcgcagt ggcctggagc cgcgaacagg gattcgtgca agcaatccag cgcgatggcc
     3781 tagaaatcct cgatcgtgta ggcggtggcg attcgtttgc ttccggtttg atctacggtt
     3841 tgatggaatt tggagacatc gaaaaggccg ttaactacgg tgcagcacac ggcgcactgg
     3901 ccatgaccac cccaggcgat acctcgatgg catcgctggc ggaagtcgaa cggctggtag
     3961 gcggcggcag cgcccgcgta cagcgataaa caccaattct gcgggggcgc ttgatcgccc
     4021 aagcgccccc gttcatcttc tatcttttgt gacaaggacg tacacacatg gctagcccac
     4081 ttttcctcga tccagatcgt ctcttcccag cagacgaaaa aacccgtgac ctggcccgag
     4141 aactctacac caccgtaaag gatctcccga tcatctctcc tcacggccac gtgaacccac
     4201 agatgcttct ggataacgaa ccattttcag acgccaccaa cctgttcctc acctacgatc
     4261 actacgtgtt ccgtatgctt cattcggcag gcatcgatct caccaagatc ggtgtgggta
     4321 aatcagatcc tgttgatccg cgaacagcat ggcgtatctt ctgcgaaaac tggcgcctcc
     4381 ttgatggcac cgcatctggc tactggctaa cccacgaatt cgtaaccctc ttcggaatcg
     4441 atgaagaacc gtgcgcagaa aacgccgata agctcttcga tattattgca gagaagctgt
     4501 cgactcctga gttccgccca cgcgcactct tcgattcctt cccaatctcc gttcttgcaa
     4561 ccactgatga tccgctggat tcactcgaat accatgccgc tcttgctgca gatgaaacgt
     4621 tcactggcca agttattcca acgtggcgcc cagatgcata tgtgaatacc cgcaagccag
     4681 aatggcgctc caaggttgaa gcactcaccg cttccgtggg ccagccggta gattccttcg
     4741 aaggctacct ggaaggcttc cgcgcttcgc gtgctagatt cattgagaac ggcgcggtgt
     4801 ccgccgattt cggtgtggca cacccactcg cagttgatat ggatgatgct gaacttggcg
     4861 cactgtacca caaggctgtt cacgaaggct tgaccgctga agaatctgac atcttcgaag
     4921 gtgccatgct cttccgcttc gctggcatga gcgtggaaga cggcctggtg atgacagttc
     4981 acccaggcgt gtaccgtaac cacaacaccg aatcgttcac cacattcggc ccagatactg
     5041 gccacgatat tccagtacaa accgaataca cgaagaacat ccagccactt cttgataagt
     5101 acggcaacga tccgcgcttg cacctggttc tcttcaccat cgacgaaacc gtgtattcgc
     5161 gtgagttagc tccacttgcg ggcttctacc catcggtgtt catcggagcc ccatggtggt
     5221 tcattgacgc tcctgatgcg gttctgcgtt tccgcgcagc caccacggaa accgctggat
     5281 tctcccgttc ttcagggttt attgatgata cccgcgcgtt cttgtccatc ccagcacgcc
     5341 acgatatgtc ccgtcgcctc gattccgtgt tcttggcgcg ttacgtgatc gaaggccgca
     5401 tttcgcgcac tgccgcgttc cactggatca aggcattgac ctctgaccag ccacgcaagg
     5461 tgttcaagct ggactaagaa taactgaaaa gcacgcggat tcttacctcg atcatggtcg
     5521 atggtgggga tccgcgcgct tttccacaac ttgcgtaagg taccaaccta gcatctgtaa
     5581 acattgttat gatgtaggtg tgtaaggcgg atctgttaag aaaactggta ggtacgtgag
     5641 taaaaagaag acagccacga tttatgatgt ggctagcgca gtgggggttt ctccgtctac
     5701 ggtatctcgc gctttttcta accctgcccg cgtatcaaca gataccgcgg aacgtatttt
     5761 tgcagctgcc cgtgatcttg gcttccgcac atcaggagcg gcctatgcca gctcagataa
     5821 agccacacgg gttctatgct tggttgttgc cgatatttct aaccctactt ttgcagcaat
     5881 gtataaaggc tttcataaag ccgcacacga acatggctat gcggtagtga tcgctaattc
     5941 tgatgaatca ggcgctctgg aagcccatac tctccgccgt gtgttgcctg atgtggatgg
     6001 ggttgccctg gcagcctctc ggcttacccc ggctgcgatt cttcaggtgg agaagagcaa
     6061 accgttggta ttgatgaacc gttacttgga cggccacacg tgcgtggtgc cagatacgaa
     6121 cggcggtatt acggcggtct gccgtgaact ggctgaacgc ggccacaagg acgtcatgta
     6181 tctttccggc ccagaaatgt cttgggcgaa tgcaatgcgc tggcgggcgt tacaagatca
     6241 gtgtgccgcc actagtttgc agcttactcg cactaagttt ttatcgcctg atctggtagg
     6301 cggtgctgat gcggcacgta tttggaaccg tggcagaaca tcggcagttg tggcatacaa
     6361 cgatttgatg gcatttgggt tcgttcgcca ggcacgccgc ctgggtgctt cgatcccgga
     6421 tgatgtgtcg gtgatcggcg tggatgattc cgtgatttgc catatggctg atcctgaatt
     6481 gtcatcgctc agcacgggta gttttgatat tggttataag gccgcgatgt cgttgatttg
     6541 gcaagcagct aaccatactc gtagggaacg ttccacgatc gttgttccga tggagtttaa
     6601 gattcgtggc agtattgcgt cacgtgggag cgaaaaagaa tgagcctttc cgaaccaggc
     6661 ctcaatgttg cactagatgc ccttgaagac gcgtatggaa tttcgccatc tgacgaggcg
     6721 atctatgacg ccttcgccag ctgggtcgaa tccaccggta agcacatgta tccgcatcag
     6781 gatgaggcgt tgttgaacat tgtctcgggc gatcacgtga ttgtggctac ccccaccggc
     6841 tctggtaaat cgctgattgc gatgcaggcg ttgtttgccg cgttggctac gggccgcacg
     6901 gcgtattaca cggcaccgtt gaaagcgttg gtttctgaga agttttttga gcttattcgc
     6961 catttcggtg cccataacgt cggcatggta acgggcgatt cgtcgattaa cgcgggtgct
     7021 ccgattgtgt gtgctacggc ggaaattttg gcgaatattg cgttgcgtga aggcgcgagt
     7081 gctgacgtgg gtgtggttgt gatggacgag ttccattttt acgacgatcc acagcgcggc
     7141 tgggcgtggc aggttccgct tttagccttg ccgcaggcac aacagatttt gctttcggct
     7201 acgttgggcg atactcgttt tttggttgcg gatttggaac ggcgcacagg gcgttcggtg
     7261 agtattgtgg acgacgccgt tcggccagtt cccttgcact tcacgtggtc tactgaaccg
     7321 atcggtgagg ttatcaaaga gctcgtagcc acccacatgg ctccagtgta tgtggtgcac
     7381 ttttctcaga aggaagcagt atcgcaagcg ttggcgttgc aatccatgcc tatcgcatcc
     7441 aaagaacaaa aagaacggat tgcggcggca ctcggttcct tcacattttc tccaggcttc
     7501 ggcaaagtcc tctccaaact cctccgatcc ggaatcggta ttcaccatgc ggggctactc
     7561 ccccgttacc gccggcttgt ggagaagctc gcacaagccg ggctcctcaa tgttatttgt
     7621 ggaacggaca cgctcggtgt aggaatcaac gtccctatcc gtactgtgct tatgacctca
     7681 ctgaccaagt ttgatggaac aaaacagcgc cacattaccg cccgtgagtt ccaccaaatt
     7741 gctggccgcg ccggccgtgc aggattcgat acggttggct acgtcgtcgt ccaagcccct
     7801 gaacacgaca tcgaaaacgc acgccgcctg cgcaaagccg gcgacgatcc cacgaagatc
     7861 aaacgcgtgc aacgggtcaa ggcgccagaa ggaacaatta gctggtccga aaatacgttc
     7921 accacactga tcgaagcaca acccgaaacg ttgacctcgc ggatgcgtgt ggaccactcg
     7981 ctcatcctca acttgctcca acgcctcgat cccatcgcgg gcgccaaaac gattctgtgc
     8041 gataaccacg aacccaaaaa agatcgcaac acgctagtac gcaaggcaat tactatctat
     8101 caatcgctgc gcacagccgg cgtcattacg cacgaagatc gcgattggcg tgcccaacac
     8161 ggcgatacgg gcgctatcca cttcactcgt gacgtgcctt ccgatttcgc actcaattcg
     8221 ccgctcgcac cattcgcgct ggccgcgttc gatttactgg agccggaaag cgcgacgtat
     8281 gcactcgacg tcgtctcaat catcgaagct gtctccgaag atccactccc cgcgctctac
     8341 gcacaacagc gccaggcccg cggcgaactc atcgggaaac tcaaagcaga tggcgtggac
     8401 tatgacgaac gcatggcgct cgtagacgaa gtgacctggc caaaaccgct tgccgacctg
     8461 ctcgaacctg ccctcgaact ctatgcgaaa accaacccgt gggtgcgcgg gcaagaactc
     8521 aaacctaaat cggtagtccg ccagctcatc gaagaagcgc tcaccttctc cgaattcatc
     8581 tcacgctacg atctctcccg atccgaaggc gtgctcctgc gctacatcac cgacgtctac
     8641 cgggctatgc gccaatctgt tcctattaac gttcgcaccc gcgaagttga ggacatcatc
     8701 gattggctcg ggcggctggt acgttccatc gattcttcac tcctcgacga atgggaggcg
     8761 ctcgccgacg ggcgcgttac cttagacgaa ctcacaacct tgggatcaga cgattccgtc
     8821 catggtgaag aagccgcctt tggtgctgat gctgacggga acgttgcctt cacacgcaac
     8881 aagcacgcct tgcgggttgc cgttcgcaac gccatgttcg aacggatcga actgctcgat
     8941 cgcgaagatt acgatgcgtt gcacgatctc gattctgctg ccggctggga tgccgacacg
     9001 tgggcagacg cgatcgcccc gtactttgac gaatacgatt tcctcggaac cgacaacgaa
     9061 gctcgcagtt cgcgcttctt ctctatcctg gaagatccaa gctacgccga tcttcttcag
     9121 gcgggaatgg cagaagattc cgcgtccgat ctgcttgaat cacaccagac tgggcgcgtt
     9181 tggttagcgt tgcaggtgct tgattctgga accgacgatg ccgcgtgggg gctgtgggcg
     9241 atcatcgatc tggatgcgtc ggatgcagct ggcacgcttg ttgtacagcc gatccgtttg
     9301 ggagaacgtt gatggtggcc attgctgaga gccttggccg cattcgtgac atcgttgatc
     9361 ggtatgcagg cggacggcac gtggatatca tgctggctac caaacaccag ccgattgagc
     9421 gcctgattga ggcatatgac gctggcggtg ttctgatggg acataatctt gtagaccaac
     9481 tggtgagtgc caatgctggc cttgccgaac atgggattca tccatacacg tcaatgattg
     9541 gccatgttca atcaaacaag ctttctagcg caatgactgt ggctgatcgg atcgacacgg
     9601 ttgattcatt gaagactgct caacgaatca accggcgcca agaagaacgc gtagcacgcg
     9661 gagaagccac cggcccctat cctgtattga tacagattaa ttcagcggca gcagacaccc
     9721 agttcggagt ggctattggt gatgtcatgc aactcgctgt ggctatcgca gatctaccac
     9781 gggtacagat tcgtggtgtc atgaccattg gtgctcgcgg atctgaaacc aatatacggg
     9841 cgtcattcgc tactacccgg cggttgtccg aagaaatgcg cacgttgccc gcattagcag
     9901 atgcggatgt tatctctatg gggatgagca acgatatgca ccttgctatt agcgaaggtg
     9961 caacggttgt gcgtgtagga actgcagttt tcggagaacg ttagaatact gtgaggccgc
    10021 gggaacggaa gatatcccgg actgcttcgg tagcttcctt cgatggcggt tcaacatcgt
    10081 tcaattggta ttccaacccg agcgatgccc acttatcacg tgccatctgg tggaacggaa
    10141 gcacttcaac acgttcaacg ctagaagccc aactttgaac aatatccgca accgcattca
    10201 cgttttctgg agcatcagtg agccccggaa caagaacaaa acggatccag atcttcttgc
    10261 cgttttctac aagacgcttg ccgaacgcca acgttggcgc aagatcgcgg cccgtagtgc
    10321 gcttgtattg ttctggaaca ccagatttca catcaagcaa aaagagatca acgtttgcga
    10381 gcatctcttc agtcatgttt acgcccaaga aaccagacgt atcaactgca gtgtggatgc
    10441 ctatttcttt acagccggcc aacaaacggg ccaagaactt cggctgcatc atcggttcac
    10501 ctccagagaa ggtgacaccg cccttcgaca ccgtgaaaac cgccttgtac cgggcgattt
    10561 tttccagcat atcagtagcc cgaactgctg tgccttcctt catcttcagg gtgtcaggat
    10621 tatggcagta caggcaccgg agcggacaac cagcaaagaa tgtggtcaaa cgcgtaccag
    10681 gcccatcaac tgccgtcacg agttcccagg agtggacaga gccgatgtca ccagcttgca
    10741 caccagaaac atgctcatgg tgtgacatcg gccctgccag ggaaactccg tccagacccg
    10801 ctccacttaa acgtgggact tcatcttcga tcggctgggg gcggtattcg ccagtgctcc
    10861 cttcagagcc ccaataccgg gtagcgtcaa ataagtcgct gctctggtgt tcaatcgatg
    10921 tagtcataaa agcggatcct taaaagattc tcacataccc tggtggaagg tacgggagat
    10981 gacgtcgagc tgctgctcac gggtgaggcg aacaaagttc actgcgtaac ccgaaacgcg
    11041 aacggtgagc tgtgggtact tttctgggtg ctccatggcg tcctcaaggg tgtcgcggtt
    11101 aagcacgttg atgtttgcgt ggtaaagacc ctgaacgcca cccttggcag cgcgctgtgc
    11161 cttcatcgat tcgagacgct cttcgtacgt cgtagccatg atattttcct ttcgtgggga
    11221 tttaaaatgt ttcgttgagc gaaactgggc gtcagccctt cttgatgaag ccagcatcca
    11281 tgatgccaac caggttatcg acctgttcag ccaagtcacg gccgagggac gatgggacaa
    11341 tcgtgttagt caaagaaatg ccatcaagag catccttgta gtgaagcttt ccaacggaga
    11401 gcatcgacgc caacatgccg tgggtatcca taccgttttc tgggtttgca cctggagcga
    11461 acggagtacc tgcacggtga cccgatggga agttaccggt tgccttgccg tatacaacgt
    11521 tcgaggtaat ggtgagaacc gactgcgttg ggattgcgtt gcggtacatt gggatgcgct
    11581 tgatcttctc catcacggtg tgaacgatgg ttgcggcgat gtcgtcggcg cgatcgtcgt
    11641 cgttaccgta ggttgggaag tcaccttcag tcttgtagtc aacgatcaag ccggtttcgt
    11701 cacgaaccgg ggtgactgtt gcgtacttga tagcagccaa agagtcagca acgatggaca
    11761 aacctgcgat gccacagccc atggtgcgaa cgatctcaga atcgtgcaac gccatttcca
    11821 tggcttcgta tgcgtacttg tcgtggctgt agtggatgat gttgagagct tcaacgtagg
    11881 ttccaacaac ccaatcgagc atgtcttcgt actttgccca gacttcgtcg aaatcgagcg
    11941 ggccatcgcc ctggatgcct tcaaaaccat caacgatctg cttcccagac atttcgtcac
    12001 ggccaccgtt catggcgtaa agaagagcct tagcagcgtt cacgcgagcg ccgaagaact
    12061 gcatctgctt accaacagcc attggggaaa cacagcaagc gattgcggcg tcatcgcccc
    12121 agtagccacg gatctgctca tcagcttcgt actggatcga cgaggtttcg atggacacct
    12181 gcgcacagaa gcgcttgtaa cccattggga gcttctcaga ccagaagatg gtgatgttcg
    12241 gttctggagc tgggccaagg ttaacgagag tctgaagcag acggaacgaa gtcttggtaa
    12301 ccaatggacg gccgtcttca ccgaagccgc catcggacca ggttgcccag tatggatcgc
    12361 cggagaagat ttcatcgtaa gcggtggtgc gcaggaagcg aacgatacgg agcttgataa
    12421 caagctgatc gatgatttcc tgagcgtcct gttcggtgat tacaccggcg gccaagtcac
    12481 gttcgaagta gatatcgaag aacgcggaga ggcggccgaa ggacattgcg gcgccatcct
    12541 gagacttcac ggatgcaagg taaccgaagt aagtccactg gactgcttcc tgagcagtct
    12601 gagctggacg ggaaatatcg aagccgtaag aagcagccat gttcttgagc ttcttgagag
    12661 ccttgatctg ttcggagatt tcttcacgat cacgtgccca atcctgggtg aacggctgat
    12721 cggcgaagag atccttatcc ttcagcttct ctgcgatgag gtgatccaca ccgtagagag
    12781 caacacggcg gtaatcgccg atgatgcggc cacggccgta tgcatctggc aagccggtga
    12841 tgatgtggga agaacgtgct gcacgaatac gtggggtgta catatcgaag acgccatcat
    12901 tgtgagtctt acggtacttg gtgaagattt tcttcacttc tggattggct tccttgccag
    12961 cttccttgat agctgtctca accatgcgcc atccgccgtt tggcatcatt gcgcgcttga
    13021 gtggaacatc ggtttgaaga ccaacgacga cgttgtcatc ttcagaaatg tagcctgggc
    13081 caaaagcatc gacatccgca ggagtgtcaa catcgacgtc gtacacgcgc ttctgacgtt
    13141 ctaccgaaag gtacttctct tccaaggttt cccaaacgcg gcgagtcttg tcagtttcac
    13201 ctgcaaggaa cgaggaatcg ccttcgtacg gcgtgtagtt cttctggatg aagtcacgaa
    13261 catcaatggc attctgccaa aggccgtcct taaagccttc ccactctggg tgtgtagcag
    13321 tttcggctgt ttgagtcacg gtttactact ccttctcatt gcaatcaacg cgggacctta
    13381 gatgtacgcc agtccgcact gaccgctttt attccccagc aactactgct ggcgctactt
    13441 ctagattaat agcccccagc acccgatact caactcaaaa agctatcagc gcaaaacaga
    13501 cggtagccct cctcacagtc cgcaattgac ggggactaaa gtccccacca tatcatggga
    13561 ctaaccaaaa tgagaatatg tgatacaaca gccgtatcgc tgaatatcac tcccctttcg
    13621 ccaactgata catccaccca aaacgatccg gcgccacccc aaactgaata tcagtcagct
    13681 tgcgataaat actctgagaa aattcgctat gcttcacaac aacacgctca tccccctgcg
    13741 tcagcgaacc aatcgccacc acagcagcgg ccgtgccaca cgcaaacatt tctgccacat
    13801 cgcctgcttt aataccgtcc cacagctcgg ccaacgtgat gctctcttca ctcaccgcca
    13861 ccccgtcgtc gtccaacaac tccaaaatcg cagaacgcgt ggaaccaggc aaaatcgtgc
    13921 cagaaagcgc aggggtgcgc acacgcccat cagccatcac cacaaaaacg ttcatcgcac
    13981 ccaactcatc gatacacgta ttcgttgcag catcaaggaa aagcacttca tcaaaaccac
    14041 gctcaaacgc gtgcgacttc gcataaaacg acgcggcata attcccgccc gtcttcacgt
    14101 cacccatccc accaggccca gcgcgatgat gttcccgctc aacccaaata tcaatcggcg
    14161 taaaaccatg cgtgaaatac gggccagaag gcgatgccac cacgccatac tcaaaccgat
    14221 gcgcggcacg cacccccaaa aacgcctcag acgcaaaaat aaacggacgc atatacaacg
    14281 ttgcgccagg cgtgcgcgga acccaacgct catcagcacg aaccagtccc gccaaggacc
    14341 ccaaaaaatc ctccaccggg aactccggaa tcatcaaccg attattcgac acgttcaggc
    14401 gcgccgcatt atacgcaggc cgaaaagtcc acacggaacc atccgcatgc cgataggcct
    14461 tgagtccctc aaaaacctct tgcccgtagt gcaaaaccgc ccccgcagga tccaatgaga
    14521 gcggcccata cggctcaatc cgcatcccgt gccacccctg ctcaggagtc cacgaccccc
    14581 gcgccatatg atccgtaaac tccacgccaa accccagccg ctccatcgcg ccttcgtacg
    14641 cttcctgcga tgccggattc ggatgcgagg ccacggcaaa acggcccgca acctgatcgg
    14701 cgcccggcca cgccgcctgc gcaaactgtt cgagtgaagt caaagagcgt accataccta
    14761 tagtctccta aacgttcccg ttgtcaacta acttatggta cgccctttgg cgctggtagc
    14821 taatcgtgga tttctttttc ggattcttct gggaaggttt cacccatata aacgggggtc
    14881 atgaggtttt ctacggagag tgtgcggttc agttccgttt cgctcatcag cccgcgttcc
    14941 agcacgatgt cgcgtaccga ttttccggtg cgagctgctt cttttccgat cagatcgccg
    15001 ttgtggtggc cgataatatc gttgagatat gtgacaattc cgatcgaatt catcacgtag
    15061 ctcatgcaga tatcttcgtt cacggtaatt ccatcgacgc agcgttcacg caaggtcacc
    15121 attgccctgg tgaggagcga aatcgattcg aagattgcct ggccgatcac cggttccatc
    15181 acgttgagtt gaagctggcc tgcttcggat gccatcatca ccgtggtgtc atttcccatg
    15241 actttgaagc agatttggtt cacgacttcc ggaattaccg ggttgacttt cgctggcata
    15301 atcgacgaac cggcttgcat ttcaggcaag ttgatttcat tgaggcctgc gcgcgggcca
    15361 gaggacagca ggcgcagatc gttgcagatc atggatagtt tcacggctag gcgtttgagc
    15421 gcaccgtgga cggaaatata ggctcccgtg tccgatgttg cttcgatgag gtttggagag
    15481 gcggtaacgt ttagaccggt aacttccgcg agtctgccga cgacgatctc ctggaaccca
    15541 tctggcgtgt tcagtttcgt tccgattgca gtggcaccga ggttgacttc aagaagcagt
    15601 tctgaggcgc gtgtgaggtt gcggatttct tcactcatca agacgccgaa ggcatcgaac
    15661 tcttggccga ctgtcatagg taccgcatct tgaagttggg tacggcccat cttgagcacg
    15721 tgggcattct tggcgccgat ggcagcgaac gatgcacgca tacgatccac ttcttcagcg
    15781 agttgttgga tcatccggta aaccgcgata cggaatcctg ttgggtaggc atcgttggta
    15841 gattgcgatt tattgacgtg atcgtttggg ttgatgacgt cgtattttcc cttcggctcg
    15901 ccaagcgttt caagggccaa gttggccacg acttcattcg tattcatatt gaccgacgtt
    15961 cctgcgccgc cctggaacac atcgacgggg aactgatcca tgcaccggcc gtcgttcaag
    16021 atgagatcgc aggcgtcgac gatcgcgcgc gacacgcgcg cggagagcac atgcttatcg
    16081 cgattggcta gggcttctgc ttttttcacg ctcaccatgc cacggataaa ttcaggaacg
    16141 tcgttgattg tgactccaga aatatggaaa ttgtcgatcg ctcgttgggt gtgaacgccg
    16201 taatatgctt catctggaat ttctctagtg ccgagtaaat cttcttcggt acgcgtttgt
    16261 accatcgtcg tctccttgaa tcgatagtga ctcttcacac accagcttaa tccgcttagc
    16321 gacaggtgtc agtataagcg gaaaaatgct cgcaattttg tttgataatg gctttttcta
    16381 gggatttccg ggactatgtg ctcataattt ctcagaacgc cagctatgat taggaagaac
    16441 tatctactat gtcatagtgt cttgtccatc actacgctct tcaggagtcc aatgtcgtac
    16501 ttatttcagc tttttgctga caaccaagtg ctgctgctct tcttccttgt aggaagcggc
    16561 acaattttgt ccaaattccg cgttcgtgga gtttctctag gtgctgccgc cgtcctcttc
    16621 ctttctatcg gaatcacggc atgggcattg tactcaggct acaagatcga agttgaacac
    16681 gatcttggcg tgctgggtct ggcgctcttc gcattcgcga tcggtatttc atccggcccg
    16741 aacttcttta acacactcaa atcctcaatc gtgcctgtgt tgttgatgct cgcaacattc
    16801 gccctcgctg gcggtgccgc agcactcgtg ggccgcgcac taggcatgga ctgggcattg
    16861 atcgccggta ccttcgctgg tgcaaccact aacaccccgg ccctgtcggc tgctggtgca
    16921 gcatccggaa accctgcact ggcaactgtt ggttacgcaa tcgcttacct cttcggtgtt
    16981 atcggcatgc tcggcttctc ggctctcgca ctctcacgcc gtagcgccga tcaggataag
    17041 ccttctccta tctgcaaccg cactatccgt gtggaacgtg aagatcagcc aactgttgca
    17101 tcgttgcgtg aaatcattgg cggaaccctt cacttctccc gtattcgccg tggcgaaact
    17161 ggccccatct ggttgccagc cgatacagat gttctagaaa aggacgatct agttaccgtt
    17221 atcggcactg ttgccgaagt tgatcaggct atcaagctgg ttggccacgg ttccagccac
    17281 tcgttgatcg ccaatcgccg ttacctcgat ttccgccgta tcacgatttc aaactctgct
    17341 attgccggcc gtaagatcgg cgaattggat gtggaggaaa agttcggcgg cacaatttcc
    17401 cgtattcgcc gtggcgatac ggatatggcc gcaagttcca ccatccgcct ccagcttggt
    17461 gatcgcgttc gtgttgttgc gccaactcac tccatgtcaa agatttccaa gtactttggc
    17521 gattcctcac atggtttgac tgacatcaac ccaatcgcac tcggccttgg tatggccctt
    17581 ggtattatca tcggcgaatg gaagatcctc accccttctg gcctaacctt ctcaatcggt
    17641 tctgcagcag gcaccctgat tgttggcttg attatgggcc gtcttggccg tatcggcaag
    17701 ttcgtcacta ctctcccatt caccacctgc caggtacttt ctgaactcgg cttgttgatc
    17761 ttcttggcct acgcaggaac gaaggccggt tcacagattc ttgttgcctt tacaggtggt
    17821 gcatggctac agatcctgct gctcggcatg atggtcacag tgattgtcgg tggcggcttc
    17881 tacctctcta tgcgtctgtt cacatccact ggcggcactc gcttggctgg cgctcttggt
    17941 ggcattcaga ctcagccagc agtcttggcc ttcgcaaatg atcgtacgtc gttcgatcca
    18001 cgcgttgctc tcggctacgc catggtttac ccagtagcaa tggtggccaa gattttcgtt
    18061 ggccaagttc tcggctcatt cggagcaatg taaccccctg taaaaacatt gagaatccgg
    18121 cacaccctcg ccgcatattg caggctgtgc attcctatca aaatgcaggt actagaagga
    18181 ccgggctaga aaagcccggt ccttctagcg ttcaaacctc acacagcatc tcgcacatca
    18241 gaaccaaggg tatctggcaa gtgagaggta tccatatcgt ggcgccatcc gttgtccatc
    18301 aacactcgcg cgatcgccag gccaaagcca atcgacatga taacgaagaa tacctccgca
    18361 aacgttgcga tcgctccttg gaaatccccc tcatttaagg caaccaggcc ccgatagaac
    18421 ggaacacccg gaatcataat aacaacggca ggaacggaca aagatacacg cgaatgcgaa
    18481 gtcttccatg caataagtgt cgcagcaatg ccaacaacaa gtgcggccaa gccaacccct
    18541 agttgccacg gcaggtgaag atggttttgc aacagtaaac ggccggtgtt agcaaaggcc
    18601 ccagccatgg ccgcagcagc acacactttc cacggggcgt tgaatagcac ggcaaaccca
    18661 taggcggcaa cgaacgacgt gaggatccga agaagtgtca tggtccagaa tgggagcggc
    18721 acaacaacag atgcctcaac atgccaatcc aaagcatgca caacgatcca cacggagaat
    18781 ccggcagacc caatcaccat caagcagtat gagaaccggg ccagtgccga ttgtacatcg
    18841 ttacgcacaa agtccaacat ggcggtagtc aatgggaagc caggaatgag ataaaggatt
    18901 gacgagatca ggccagattc atactggctc aggtagagca aaccaccgaa gctaccaact
    18961 gcaaggaggg taatgtatac aagcgtggag gcaacagcac acacgatcca aataaggaag
    19021 tgcgcgattc cgcgccccaa caacagttta cgaataagct gcccgattcc tgcagcgaag
    19081 aacacggttg tgcattccac ggcacgcccg ccgttgagga agcagaatcc agcacaggcg
    19141 attgcggagg ccagcacggt tgtccagagc ccgtagtgcc gatcgcgtgc ggttgtttct
    19201 ttgagaatca ggcgcaggtc agcggcgctc atgccttcgc gaagttgcga gacgccttgc
    19261 atgatccgat ccagcttttc ggcgttcacg cccacgcggc gttgttctgc gaagctggtg
    19321 taggattctt ttccattcca tgcggttgcg gtgatgtctg tcatggacac ggccgaatcg
    19381 agccgcgtca gtccgattgc tttcgcggcg cgtgccatgg cggctttcac gcggtaggcc
    19441 ccagcgccac aggctaggag catggttccg agcatgagga ttgagcgtag tttttcggct
    19501 atcgtttcgg agctagtggc tgattctgtt gactgatggt ccatacttct ctcacaactg
    19561 cttaaaaatg gtggaatatg cgcgaacatt ctattcccgc atgtgagaga tctaccgggc
    19621 cgtaacgccc aattatgatt tttgtccccg atctgtatct cacattttgg ggagggttgc
    19681 tacccacatg tatgtcacgt atgggatttc tacggtgtgg tgttcctcgt atcctaattt
    19741 ttcgtggagg taccagcgca gatttgcttg cattcgctct tggttcgcgg gtgtggaggt
    19801 aatccaggag gatcgcgttg tgccgagttt gcatacgttg cgtggggtga ggtgatcttg
    19861 ccacacgttc acggtgagtt gtggggtgga aaatttttcg acgacgacgg gcgtatcggt
    19921 tactctgtgc acgtctcctg atctcatgat tctagtcaat cgtttgaccc aggggatgga
    19981 gacatccatc tggttgaaca agatcacgag cttgcctcct ggtttgagga ttcgggccgc
    20041 ttcggcactt gccgcacgag gatctaccca atgccagctt tgagcgtaaa acaccacgtc
    20101 acacgagtta tctggaaggg tagtgtgttc tcctgtggca tcaataatcc gaacgatgtc
    20161 caagatccga ttggtgagct gctcgcgcat atctgggctt ggttcgatcg cccacacgct
    20221 ccccttaagc cccacaattt ccggcagcat cgtcgtcaat ttccctgtgc ctgccccgat
    20281 gtccgcaacg caaggcgccc catcgacgtc gtcaaatagg ggctcaagta acgtacgtga
    20341 ataaccgggc cgcacgtcaa cgtacgtggc tgcgctcgtg ccggcgttgt gaaacggatt
    20401 cgctagggaa gtcataccta ttattgtgaa acaaagcggg gaaaatatct cgaactaaag
    20461 aaaacttgac caatctaacc actcgcaacg ctcgataggc gcgcaactcc cgtaaaatgg
    20521 aacataggtg agccgggaag tctggtcggc acgtttaaaa taaccaaccg gaaaagaggc
    20581 accgtgactc aacgccccac tgctctccgt catgttcttt cgtacggaag ctatgcagaa
    20641 cacttgcgta tcggaaaaat cctacgccgc gaaaccacgg gcggaatcgc cctcatgatt
    20701 gccgcgcttg ttgcgatcat ctgggcaaac tcaccgtggg cagaatcgta cactgcgctg
    20761 cgcgatatga aacttgggat cgatgcgctc cacctccagc tgtcagttgg gcactgggcg
    20821 gcagatggtc tgctggcaat tttcttcttc ctggtggggc tcgaactcaa acaggaattc
    20881 gtggcgggcg atctgcgctc cccaagccgc gccgttgttc ccgtagtggc ggcggtgggc
    20941 ggcgtggttg tgcctgcgct catttacgcg ttcttcaact ggaattctcc tgaaacgttg
    21001 caaggttggg cgattccaac cgctacggac atcgcgttcg ctgtggctgt gctggccatt
    21061 ataggatcac atttacctag cccgttgcgg ttgttcttgc tgacgttggc tgtagttgac
    21121 gatttgatcg ctattactat catcgccatc ttctataccg gcgagatcca cggcacctac
    21181 tttgcgctct tcctgatccc tgctgcgatt ttcggggtgc tcgtgcagcg cttccacgtg
    21241 ttctgggtga aacatcgctg ggcgtcctgg tttatcctct tccctatcgc cgctgtggcc
    21301 tggtacttcc ttcacgaagc cggcatccac gctacgatcg ctggtgttgt gttgggcttc
    21361 cttgtgcctg tggcattcaa gcatgagggg gcacaagagg ctctctcgga gcatcggccg
    21421 gatgtgcatg gccacggcga tcacgctccg gggcttattt cgatgtttga acatgggatc
    21481 cggccaattt cgtctgggtt cgccgttccg gtgttcgcgt tcttctctgc gggcgtgact
    21541 gttgggggtt gggacggatt cgtggcgtct ctttcttcgc cagttgctct tggcatcttg
    21601 gccgggctga tcattggcaa gccgttgggt attgtggcgt ctacgttcgt tttaacgaag
    21661 ctgacccgcg ctaagctcga tgactctatc gcgtgggccg atatgatcgg tgtgggcttc
    21721 ttggcaggga tcggtttcac tgtgtcgttg ctggttggcg aactctcctt cggtttgggt
    21781 gatgccaata atgacgctgc caaagtgggt atcctgctgg cgtcggtgct ggctgcgctg
    21841 atcgctgcac tcattcttgt tccgcgcaac aaccgttacc gcaggatcga agaagcagag
    21901 cacgcagacg ccgatgcgaa cggtattccg gatgctttcg agcgcgccaa caaggagctt
    21961 gcctagctct taagccaacg caacgaactc aatcggaacc cacgtgctgc tccactggcc
    22021 tgcgtgttcc accgactcac gctgctccac ccaaccccgc gctgctccac aacgcaggga
    22081 ggccgtatct tgcgatacgg cctcacttgt tactaaacac agatgctagc gataatttat
    22141 cggtataaaa ccgaatccgc gttagtacta tctccacgga tcgcggtgta aaggatctgg
    22201 aacaggcgaa tcaagccgaa agcaagaata atatgtccaa agccagcgat gcctgagaat
    22261 gctggaatcc attcttccgg gccatatacg atattcacaa ctccctgagt gaacatcgct
    22321 gctgttgtcc atgccaagcc cacgttatag agaataaacc acatgttaaa gcgcttatct
    22381 tcggaaagat caaagagctt atttagtccg ataagaatca tgaagaaaag cgtgccgagc
    22441 acgagagtat gagtgtgaat ccggctcagt tgggtatccc ccacataggc gtatgcgcga
    22501 gtgaactcac gatagaagac tccagagata agcccgaccg ccaaatatga tgccgctgca
    22561 ataaataatt tccgcatgcc ttcactgtag cctattttta accatttaga gacgaaatac
    22621 cccttgcgac gtctctatct tcaatattta caccataaaa catcggatta gctcaggccc
    22681 gcggcatgcc gggccgaaaa tacgcacctc taggccaacc tctagaccaa aattcaccgc
    22741 ttctagaccg gtgcgatgtc taaataggcg ggagattgca cgggagtgct gtatatggct
    22801 ctcttgtcgt ctgtggcgct ttttgatgac atatggtgat tgttgtagtg ttttacgctg
    22861 tttgataact actgtgtcgt ttttagcgtg ttgttggtgt gggttatata tagatttagc
    22921 ccacgtgtgt gggcttggtg ttgttgtgtt gtggggtgtg tttgaggggc tgaccggtgt
    22981 gttggttagc ccctcgatgg tgtggtgacg gcggtgtcct actctcccac actctctcgg
    23041 gtgcagtacc atcggcgctg gtaggcttag cttccgggtt cgggatgggt ccgggcgttt
    23101 ccctaccgct gtgaccaccg tcaaaacggt tggatgaata gtttctgtgg ttggtttggg
    23161 ggttgggagt tgtatagtgg acgcgtgcgt gtttgttacg tgtttttgta ggtggttggc
    23221 cattagtacc agtcagcttc acccgttacc gggcttctac gtctggccta tcaaccctat
    23281 ggtctgtagg gggccttccg atcgttagga tcgtggaaac cttatcttaa agcaggctt
//
