LOCUS       c00003_NZ_UHIY..       24679 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_UHIY01000001.1 Yersinia kristensenii strain NCTC11471, whole
            genome shotgun sequence.
ACCESSION   NZ_UHIY01000001
VERSION     NZ_UHIY01000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:42:35
            Original ID  :: NZ_UHIY01000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1383088
            Orig. end    :: 1407767
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24679
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1393088:1397767]"
                     /cutoff="10000"
                     /detection_rule="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /neighbourhood="10000"
                     /product="Formate_dehydrogenase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14679
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /neighbourhood="10000"
                     /product="Formate_dehydrogenase"
                     /protocluster_number="1"
     cand_cluster    1..24679
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /kind="single"
                     /product="Formate_dehydrogenase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24679
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Formate_dehydrogenase"
                     /region_number="9"
                     /rules="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /tool="gutsmash"
     CDS             complement(605..1369)
                     /locus_tag="ctg3_1223"
                     /transl_table=11
                     /translation="MQDLNNAMLIKKNNQLNNILVAIAFLFSAGVSEAAISLDRTRIIF
                     NSTDTSASIVLQNKSATSPYLAQSWLENTAGQKVDSPLSVLPPIQRIDAGQKTLVRIIS
                     LPDVKQLATDRETLFYFNVREIPPKSEMTDAVQIAIQSKIKLFYRPEAIKADYKAIWQE
                     KLQFSQKIESLKIHNPTPYYVTLGHLNRDNRGNFPGFDSVMIAPFSTESIKTPGYNGDY
                     YSIGYMDDFGQMIIRHVNCSIGHCQIQAVEKK"
     CDS             1601..2161
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_1224"
                     /sec_met_domain="Isochorismatase (E-value: 2.3e-24,
                     bitscore: 84.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNSALLIIDVQQSFEHKSFWQQDDLPAFSAALNQLITGCKQRGV
                     ALVDVFHVAPEGPFSLASGYVKPMSLVSHQADVTVQKRVHNALTDSGLDQWLKERQINH
                     LIIAGMRTEQCCETTARVASDLGYQVTFVTDATLTFPMTQPNGIVLSSAELKLRTETVL
                     IDRFAAVRTVAETLHALDESCNK"
     CDS             2181..3161
                     /locus_tag="ctg3_1225"
                     /transl_table=11
                     /translation="MSLSSKGDISTGNGELTMRRNVYFLLLPGVLSLDLTGPAETLRLA
                     GAFNLCYISPLPQVMSSTEMMLGQLQPLPDSLPEGSLLVVPGVSDSRHYFATETAAIAR
                     HWLQQQTVAIKQQKTILVCVCSGALLAAQAGLLDGYQCTTHHHVLERLRQQAPAAQTKE
                     NRIFVEDRGVYTSAGITAGIDLSLHLISRYCSPQTALEVAREMVVYFRRSGDDPQLSPW
                     LRYRNHLHPAVHRAQDVMSAAPQEEWSLLQVAQKAHVSSRHLTRLFREHVGISVREFHE
                     QLRVAVAEVRLQEGLNLEKAALAAGFSSARQLRRAQQRGRPQLTD"
     CDS             complement(3150..4142)
                     /locus_tag="ctg3_1226"
                     /transl_table=11
                     /translation="MTNKIGWIDNLRAVACIMVVMIHATTYYVTRGAQVGEVNWDIANL
                     LNSASRACVPLFFMISGYLFFGEKSAQKKHFTRIGLCLLFYSLIALIYISTLTPINGWA
                     ALNNILQKPVFYHLWFFYAIIVVYLVSPLINVKPVSGRYLAVVILLLAVVANPQTSQYT
                     VGDFHLLPINLYIYGDTFYYLLYALLGRAIGMLDTRGRGISWGAALLFIMSVVFIAIST
                     EKQTRINGSFADTFYMYCGPLVFVAAVSLLVWFKNCLNQPIAWLSWLAGHSLAIYGFHA
                     LIIHFIRTHHYDFTDYPVLDIFYVFALALALSTLLSMGLQRIDRRRLVS"
     CDS             4387..5616
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 114.7; E-value: 1.4e-35)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_1227"
                     /sec_met_domain="MFS_1 (E-value: 9.7e-34, bitscore: 114.7,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTSFSPATRLGRRALLFPLCLVLFEFATYIANDMIQPGMLAVVA
                     DFNASVEWVPTSMTAYLAGGMFLQWLLGPLSDRRGRRPVMLVGVAFFVVTCLAILLVTS
                     IEQFIAMRFLQGIGLCFIGAVGYATIQESFEEAVCIKITALMANVALIAPLLGPLAGAA
                     LIHVAPWQSMFVIFAVLGAISFAGLWRAMPETASRKGEKLSVGAMWHDYKQVLANRRFL
                     CGSLALGFASLPLLAWIAQSPVILISGEKLSTVEYGVLQVPIFGALIIGNLTLARLSGK
                     KSIPQLIRYGAGPMIIGLMIAAGSTLYSSHAYLWMTAGLSLYAFGIGLANAGLVRLTLF
                     ASDISKGTVSAAMGMISMMVFTLGIEFAKVAYLWGNSGIFNLFNLISGLLWLGLVMIFI
                     RRQPDSLATE"
     CDS             complement(5680..7572)
                     /locus_tag="ctg3_1228"
                     /transl_table=11
                     /translation="MIIATAGHVDHGKTTLLQAITGVNADRLPEEKQRGMTIDLGYAYW
                     PQPDDSIIGFIDVPGHEKFLANMLAGVGGIDHALLVVACDDGVMAQTREHLAILRLTGH
                     PTLTVALTKADRASGERIEQVRQQVMAELSAQGWPAEQVTLFVTAATADRGISELREHL
                     AQCHQQDENNSRLQRRFRLAIDRAFSVKGAGLVVTGTALAGKVAVGDTLWLTGSDCPVR
                     VRGIHAQNQDTQQAQAGQRIALNITGDISKQQIDRGDWLLAQQPPESVDRVLVIVDADE
                     PIQHWQPLHLHHAASHITGRFSLLNSSQQEGDKPQWILAEILLDTPLWLAENDRLILRD
                     IAAKKTLGAARVIHLAVPKRGKRQPAFLAWLTALAQAKSDSEVLGLHLAQGPLSVGKFS
                     WARQLSSHDMAALLTGTDCVIAGDIALSSPHAQQAQQTLLHVLCLYHQQHNDQLGLGRA
                     RLRRMALPTLDETLVFRLIDDLLTQGALKNTRGWLHLPEHGLGFTEQEQARWQQVAPYF
                     SDDPWWVRDLATELVMDEGEMRSLLRKAAQLGYITAIVPDRYYLSQRIEQFADLIRELD
                     ASQGSASAADFRDKLGIGRKLAIQILEFFDRSGFTRRRGNDHFLRDRGLFSAVN"
     CDS             complement(7569..8957)
                     /locus_tag="ctg3_1229"
                     /transl_table=11
                     /translation="MSAESHHLYSQLPAIDSLLRSSEMAPLLDEYGAALLTETLRLMQA
                     EAREYIGQFHTLADWCADWPAALRQRLNQRQPALKPVFNLSGTVLHTNLGRAPLAESAI
                     AAVTDAMRGAVTLEYSLSNAVRGHRDRAVADLLCELTGAEDACIVNNNAAAVFLMLTVM
                     VAGKQVVVSRGELVEIGGAFRIPDVMRQAGCELVEVGTTNRTHLKDYHQAINEHTGLLM
                     KVHTSNYSIEGFTASVTEQQLAALGHEFAIPTATDLGSGSLVDMTRYGLPAEPMPQQLI
                     AAGVDLVTFSGDKLLGGPQAGIILGKKQWIEQLQQHPLKRVLRADKMTLAALDATLRLY
                     QQPDRLSELLPTLRLLTRSAQNIAESAQRVLAALNGSYGADFTLAAEPCWSQIGSGSLP
                     VDRLPSWAVTFMPKEGSGSALEALTARWRGLAKPVIGRVADGRLWLDLRCLEDETALLR
                     ELAP"
     CDS             complement(9072..10001)
                     /locus_tag="ctg3_1230"
                     /transl_table=11
                     /translation="MSIRIVPKDQLGKQSEKGTTAGNIPPLLFANLKSLYTRRTERLQQ
                     LALDNPLADYLDFAAKITQAQQKALHDHPLVLDMQAELAQSAASGKPPLDLSVFPRTDH
                     WRKLLSALIAELRPDAPDPIAAVLDNLDKASVHELELDADALLNREFANVGSEKAPFIW
                     AALSLYWTQMASQIPGKARAEYGEHRQFCPVCGSIPVSSVVHIGTHSGLRYLHCNLCES
                     EWHVVRIKCSNCEQTRDLNYWSLDSELAAVKAESCGDCGTYLKILYQEKDPMVEAVADD
                     LASLILDAKMEGEGFARSSINPFVFPGE"
     CDS             complement(10001..10651)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Ni_hydr_CYTB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_1231"
                     /sec_met_domain="Ni_hydr_CYTB (E-value: 4.4e-23, bitscore:
                     79.8, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKEKRIQRYSAPERINHWIVAFCFMLAAISGLGFFFPSFNWLMN
                     IFGTPQLARILHPFAGVIMFAAFLIMFFRYWKHNLINKEDLEWAKNIHKIAMNEEVGDT
                     GRYNFGQKCVFWAAIISLVLLLASGVVIWRPYFAPSFPIPLIRLALLVHSLAAVGLIIV
                     IMVHIYAALWVKGTITAMVEGWVPAAWAKKHHPRWYREVNAKRQLQNKQEEKP"
     CDS             complement(10648..11619)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Fer4_11"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Form-deh_trans"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 24; E-value:
                     1.5e-07)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_1232"
                     /sec_met_domain="Fer4 (E-value: 1.6e-05, bitscore: 22.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_11 (E-value: 2.2e-25, bitscore: 86.7,
                     seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0038, bitscore: 15.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Form-deh_trans (E-value: 1.9e-22,
                     bitscore: 76.8, seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLQTQDIIRRSGTNSLTPPPQARNHQEEVAKLIDVTTCIGCKAC
                     QVACSEWNDIRDEVGHNVGVYDNPADLTAKSWTVMRFSEVEDEESGKLEWLIRKDGCMH
                     CADPGCLKACPSEGAIIQYANGIVDFQSEHCIGCGYCIAGCPFDVPRMNKDDNRVYKCT
                     LCVDRVGVGQEPACVKTCPTGAIHFGTKEAMKEVAAGRVSELKTRGFDNAGLYDPAGVG
                     GTHVMYVLHHADKPQLYHGLPENPTISPTVTFWKGIWKPLAAIGFAATFAASIFHYVGV
                     GPNRVEEEEDEDDKSDSTPSDTASKAPEPTTAEHSDDGETRK"
     CDS             complement(11632..14043)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molydop_binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molybdopterin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_1233"
                     /sec_met_domain="Molybdopterin (E-value: 3.4e-23, bitscore:
                     80.2, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 2.8e-17,
                     bitscore: 60.7, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNHWVDIKNADLIIVMGGNAAEAHPVGFRWAMEAKIHNNAKLLV
                     IDPRFTRTASVADFYTPIRSGSDIAFLSGVLLYLMTNNKINREYVEAYTNASLLVREDY
                     TFDDGLFSGYDAENRKYDKTSWNYQLDENGFAKRDVTLQDPRCVWNLLKEHVSRYTPDV
                     VSNICGTPKADFLQVCEYLAETSVSNKTATFLYALGWTQHSVGAQNIRTMAMIQLLLGN
                     MGMAGGGINALRGHSNIQGLTDLGLLSQSLPGYLNLPSEKQPDIDIYLKANTPKTLLPG
                     QVNYWSNYPKFFVSLMKSFYGDNAQKENGWGYDWLPKWDKGYDVLQYFEMMSQGKVNGY
                     ICQGFNPVASFPNKNKVVASLSKLKFLITIDPLNTETSNFWQNHGEFNDVDPSKIQTEV
                     FRLPSSCFAEENGSIVNSSRWLQWHWKGADSPGEALNDGAILAGIFSRLRDMYRREGGA
                     VPEQVLNMTWDYLTPDNPEPEEVAQESNGKALADITDADGKVLVKKGEQLSTFAHLRDD
                     GTTASGCWIFAGSWTPAGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQG
                     KPWDPKRQLLEWDGAKWGGVDIPDYSAAAPGSDVGPFIMQPEGMGRLFAIDKMAEGPFP
                     EHYEPFETPLGTNPLHPNVISNPAARVFKDDLAAMGSHEQFPYVGTTYRLTEHFHYWTK
                     HALLNAIAQPEQFIEIGEKLAAKKGIKQGDTVKVSSNRGYIKAKAVVTKRIRTLNVHGQ
                     EVDTIGIPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKAFLVNVEKV"
     CDS             complement(14092..14679)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molybdopterin"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molybdop_Fe4S4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_1234"
                     /sec_met_domain="Molybdop_Fe4S4 (E-value: 4.3e-20,
                     bitscore: 69.4, seeds: 55, tool: rule-based-clusters)"
                     /sec_met_domain="Molybdopterin (E-value: 1.2e-06, bitscore:
                     25.7, seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVSRRQFFKICAGGMAGTTVAALGFTPSVALAETRNYKLLRARE
                     TRNTCTYCSVGCGLLMYSLGDGAKNAKESIFHIEGDPDHPVNRGALCPKGAGLVDFIHS
                     ESRLKYPEYRAPGSDKWQRITWNDAFDRIAKLMKEDRDANFIKTNDAGVTVNRWLSTGM
                     LCASASSNETGYLTQKFSRALGMLAVDNQARV"
     CDS             14863..15717
                     /locus_tag="ctg3_1235"
                     /transl_table=11
                     /translation="MGYNFQGRIVSQIKPSDIDLSTGICGARQLNVLQRHQMAEPQLDW
                     LAEEVPVALVYNGISHVVMMATPKDLEAFALGFSLSEGIISTPQEIYAIDVNPGCNGIE
                     VNIELSSRRFVGLKERRRAMAGRTGCGVCGIEQLDDIFRPITPLPFTQSFDFNHLDHAL
                     AQLKQVQTVGQLTGCTHAAAWINPQGELLGGCEDVGRHVALDKLLGIRAKQPWRQGAVL
                     VSSRASYEMVQKAAMCGAEILFAVSAATTLAVEVAERCNLTLVGFSKPGRATVYTHPQR
                     INT"
     CDS             15841..16464
                     /locus_tag="ctg3_1236"
                     /transl_table=11
                     /translation="MSYSLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANTVLES
                     FPELAKFSVEDLIKDLDKVPAEKRTFMRNNAGGHANHSLFWKGLKLGTTLTGDLKAAIE
                     RDFGSVDSFKEKFEQAAATRFGSGWAWLVLKDDGKLAVVSTANQDSPLMGEAVSGASGF
                     PIVGLDVWEHAYYLKFQNRRPDYIKAFWNVVNWDEAAARFAQAK"
     CDS             16784..18733
                     /locus_tag="ctg3_1237"
                     /transl_table=11
                     /translation="MAGFSKIFGNFENVKVGKKLGLSFFLMLLLVGIIAGTTAYHFSVI
                     EEHAYKVDLSYKINDEANQAKYNRALYERTYDLKYIEENSEHINKIKSLLDQSETLGWS
                     ADNRKTISSISDVVEEYLQQQSNFVNAVAHKDDVRKSWNISETQKNLNELQQSLLNEGA
                     DTNTQILLAEMNQKLMTVRYNARGLLLDRNQDAESSLITSINIANSAANAFMPVLSADQ
                     QKLLAPVISSLSAYKDNVLAYLPAYQQELEVGKVMEDNANELNKLATHLFTQELQGTHD
                     EIDNAQLQLTITVIAALLFGLLISWRMTRQITVPLRTTLAMAERIANGDLTAETTSTRT
                     DELGLLMNTVARMNENLRAMIDEIRIGVSQVSHASGEIAAGNTDLSSRTEQQAAAVEET
                     AASMEQLNATVKQNADNAHHANQLATEASQTAQQGGKLVNDVVRTMNDISGSSKRISEI
                     TSVINSIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSAQAAKEIEGLIGE
                     SVSQVNAGTSLVQNAGQTMEDIVRSVTHVRDIMAEIASASDEQSRGITQVSQAISEMDS
                     TTQQNAALVEESAAAADSLAEQAILLEQAVAVFRLSEAEVETVQSNTSASRVATPRPAP
                     DASRNDQQDNWETF"
     CDS             complement(18898..19254)
                     /locus_tag="ctg3_1238"
                     /transl_table=11
                     /translation="MKEHAEIKRLSDMLDALNHKDPAVIQQGNMELIAQHMKEKEKLAA
                     EIQRLKEVRVKNLSAEAQKLAQLPFSRAITKKEQADMGTLKKAVRGIVVVHPMTALGRE
                     MGLKEVTGYAKKAF"
     CDS             complement(19347..20828)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_1239"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7.6e-24, bitscore:
                     82.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLVMNEIRYLQVADNLAQAIKNGSLLAGSRLPSVRSYAQSHQVS
                     INTVVAAYRTLEDRGLIEARPQSGFYVCSPSTAVVPTATVGKPVDEVLDLIDTVFAAQQ
                     NPHFTNISLACPQTGDFYPSAKLGRIMASLLRRQPQLISQYALPPGNQRLRQQIARRAM
                     TLGMLADPADITITHGCMEALQLALRVTTKPGDCVGLESPTYFYLMPLLASLGLKAVEI
                     PTDPQQGLSLDVLELLLKEGRLNALIAMPTVQNPMGYTMPLTAKKRLAQLMNDHQVPLI
                     EDGLYAEIQFGSTLSPAVKAFDRDGWILFCSSFTKTLAPDFRIGWIDGGRFAEALHKLK
                     AVSSMAEPMLLSETLALFLESGGYDHHLRSLRRRYAQQVQQAQQLITRYFPRGTTVTQP
                     AGGFVFWVEFPDSVDTVALFHQLLQEQICLTPGTLYSPSGRYRNAFRLSCCYPFNSRYT
                     GALERLGAVACEISGLPAGMQWQPVQEAAAERPTS"
     CDS             20934..21599
                     /locus_tag="ctg3_1240"
                     /transl_table=11
                     /translation="MLNLLVIRFLKNKKIGVYIMLDSAFISYVTVMSITPGPNNLLLAA
                     SGVNFGLRRTFPMMLGITFGCALQCALMTTLLAFILSWVGVVRLPLVTLGGGYLLWLSW
                     KIFNSGTPNARDSEQPMGFIQGALFQAINPKAWLMAMNVAILFTPREGATLSHTLLIVG
                     GFALLNLPCVAVWAVMGDQLRHALRVNWKLRLFNGVMGGLMAITALWLLADEWLTALA"
     CDS             complement(21600..22076)
                     /locus_tag="ctg3_1241"
                     /transl_table=11
                     /translation="MAAVDLLAEALNILVVQVFRKDDYAVKYAVEPLLVGDGPLGELSV
                     RLKLVYALGVITRHEYEDAELLMALREELNHDGTEYRFTDDEILGPFGELHCVAELPPV
                     PTFLRPDEADASLIAMQRQRYQQMVRSTMVLSITELLSRISQKQVSKLSPLGHA"
     CDS             complement(22180..22299)
                     /locus_tag="ctg3_1242"
                     /transl_table=11
                     /translation="MSLLLLVIRVIECSQRTCGLKYDGDKYRVGLRGIYPLIA"
     CDS             complement(22368..23531)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mannitol_dh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mannitol_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_1243"
                     /sec_met_domain="Mannitol_dh (E-value: 3.9e-25, bitscore:
                     86.7, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Mannitol_dh_C (E-value: 1.1e-66, bitscore:
                     222.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALHFGAGNIGRGFIGKLLADAGAQLTFADVNQPLLDELNKRKS
                     YQVNVVGEQARVEEVKNVSAVNSGSPEVVALIADADIVTTAVGPQILARIAGTVAQGLV
                     TRHQQGNTRPLNIIACENMVRGTSQLKQHVFAALPESEQAWVEQHVGFVDSAVDRIVPP
                     SEAGSTDILAVTVETFSEWIVDGTQFKGQPPQIAGMELTDNLMAFVERKLFTLNTGHAI
                     TAYLGQLAGHQTIRDAILDPAVRQTVKGAMEESGAVLIKRYAFDPQKHAAYIDKILSRF
                     ENPYLHDDVERVGRQPLRKLSAGDRLIKPLLGTLEYQLPHNNLVTGIAAAMSYRSEQDP
                     QAQELVELLAKLGPKATLAQISGLPADSEVVEQAVSVYNAMQDKLAH"
ORIGIN
        1 cacaggagcc gagagtgtcc ctgcgctgat tgatgaagtc gaaaatacgc cgcaagctgc
       61 cacgccagtg tggtttttgc cctatctttc tggcgaacga actcctcata ataatccgaa
      121 tgctaaaggg gctttctggg gctttaccca tgaacatggc cgggcagatt tagcccgtgc
      181 ggtattggag ggagtaggat ttgctttagc tgacggaatg gatgctctgc atgccagcgg
      241 gttacaaccc aaatcggtca ccttaattgg tggcggagcg cgaagcccat attggcggca
      301 aatgctggca gatattagcg gccaaacact ggagtatcga actggcggtg atgtcggccc
      361 tgctttaggt gccgcccgat tagcccaaat tgccctcaat ccggatattc cattagctga
      421 tttattacct gcactgccac tggagcaaac acatttgcca gatgcacagc gccatcagaa
      481 ttatgccgct cgtcgtgtca cctttaaaaa gctttatcag caattactgc cattatgtga
      541 ataagataaa ttgtgtaaat aagctaaagt tcaggttata acgcataaca ggttgtagag
      601 aggattattt cttttccaca gcctgaatct ggcaatgacc tatcgagcag ttaacatggc
      661 gaatgatcat ctggccaaaa tcatccatat agccgatgct ataatagtca ccattatatc
      721 cgggagtctt aatggactca gtgctaaatg gcgcaatcat gacactgtca aaaccgggga
      781 agttaccgcg attatcccga tttaaatgcc ctagcgtgac gtaatatggt gtaggattat
      841 gaattttaag agattctatt ttctggctaa actgtaattt ctcctgccag atagccttat
      901 aatccgcttt aatcgcctct ggccgataaa atagttttat tttgctttga atagctattt
      961 gtaccgcatc agtcatttca ctcttcggcg gtatttcccg cacattaaaa tagaacaaag
     1021 tttcacgatc ggtggctaac tgcttaacat ctggtagcga gataatgcgc accaaagttt
     1081 tctgacccgc atcaatccgt tgtatcgggg gtaatacaga caatgggcta tctacttttt
     1141 gcccggctgt attttccaac caggattgcg ccaaataagg cgatgtcgcg cttttatttt
     1201 gcaaaacaat actggctgat gtgtcggtac tgttgaaaat aatccgtgtt ctatccagac
     1261 ttattgccgc ttcactcact ccagcactaa acaaaaatgc tattgccact aggatgttat
     1321 ttaactgatt atttttcttt atcaacatcg cgttattaag gtcttgcatg gtttattcca
     1381 ttccaatgta tatcgtctta tcgtgaataa catttttcct taatcagtgt tttcggccaa
     1441 taaactgttt taatgagtct tttttcatta actttttaat ctacttgggg cggaagtaaa
     1501 atctggtccc ttttattccc tatgatggcc ggatttggca tttcactcag ctcaaaaccc
     1561 gccaataatg gagccatacc cctacggcgg agggccggaa atgactaaca gcgcattact
     1621 gatcattgat gttcaacaat cattcgaaca taagtctttt tggcagcaag atgatttacc
     1681 cgctttctct gcggctctga accagctgat tacaggctgt aaacagcggg gcgttgcgct
     1741 agtagatgtc ttccatgttg ctcctgaagg cccgttttca ctggcttctg gctatgtgaa
     1801 acccatgtct ctggtgtccc atcaggcgga tgtcaccgtg caaaaacggg tgcataatgc
     1861 gctgaccgat tccgggctgg atcaatggct gaaagagcgg caaataaatc acctgattat
     1921 tgcgggcatg cgcactgaac aatgctgtga aaccactgcg cgcgtggcgt cggatttagg
     1981 ttatcaagtc acttttgtca cggatgccac attgacgttc cctatgactc aacctaatgg
     2041 catcgtcctg agcagtgctg aattaaaatt acgcaccgaa accgtgctca tcgaccggtt
     2101 tgctgctgtt cgtaccgtcg cggaaacatt gcatgctctg gatgaatcat gcaataaatg
     2161 atatctaacc agagagcctt atgtccctat cgtcaaaagg ggatatatca accggtaacg
     2221 gtgaattaac aatgcgacga aatgtctatt ttctcttgct gcctggcgtg ttgtcactag
     2281 atttaaccgg cccggctgaa acgctacggc tggcaggggc gtttaatctt tgttatatca
     2341 gccccttgcc acaagtgatg tcatccactg agatgatgtt gggccagttg cagccgctac
     2401 cagacagctt accggaaggc agtttactgg tagtgccggg tgtgagtgat tcacgccact
     2461 attttgcgac cgagactgca gcaatagctc gccactggct acaacagcag acagtcgcga
     2521 ttaaacaaca aaaaacgatt ctggtttgtg tctgttccgg ggcgttgttg gcagcgcaag
     2581 ccgggctatt ggatggctat caatgcacca ctcatcatca tgtgcttgaa cggttgcgcc
     2641 aacaagctcc ggcggcccaa accaaagaaa accgtatttt tgttgaagat cgcggggtct
     2701 ataccagtgc ggggattacc gccggtattg atctctcttt gcatctgatc agccgctatt
     2761 gcagcccgca aaccgcgctg gaagtcgcgc gggagatggt ggtttatttc cgccgctcgg
     2821 gggatgaccc gcaactttcg ccgtggttac gttaccgcaa ccatctccat ccggcggtac
     2881 accgagcgca ggatgtgatg tccgcagccc cccaagagga gtggtcgctg cttcaggttg
     2941 cacagaaagc ccatgttagt agccgtcatt taacccgatt attccgcgaa catgttggga
     3001 tcagtgtgcg cgaatttcac gagcaattac gggtagccgt ggctgaagtc cgcctgcaag
     3061 aggggcttaa tctggagaaa gcagcactgg cggcgggttt ttcctccgcc cgccagcttc
     3121 gacgcgcgca acagcgcggc aggccacagt taactgacta atcgccgccg gtcaatgcgc
     3181 tgtaatccca tggacagtaa ggtgctcagt gccagtgcta gcgcgaagac atagaaaata
     3241 tccagcaccg gatagtctgt aaaatcataa tgatgggtgc ggataaaatg aataataagc
     3301 gcatggaaac cgtaaatcgc cagtgaatgc ccggccagcc aactcaacca ggcaataggc
     3361 tgattcaggc aatttttaaa ccacaccagc agtgataccg ccgcaacaaa aaccaacggg
     3421 ccgcagtaca tatagaatgt atccgcaaag ctgccattga ttcgcgtctg tttctccgtt
     3481 gagatagcaa tgaataccac actcataatg aacaacaatg ccgcgcccca actgataccc
     3541 cgcccccgag tatcgagcat accaatggcc cgccccagca gcgcatacaa taagtaatag
     3601 aaagtatcgc cgtagatata gagatttatc ggcaataaat ggaagtcgcc aacggtgtat
     3661 tgactggtct gtgggttagc caccaccgcc aacaacagaa tgaccaccgc cagatagcgg
     3721 cctgataccg gtttaacatt aatcagcggt gaaaccagat aaaccacgat aatggcgtag
     3781 aaaaaccata aatgataaaa caccggtttt tgcaggatat tgttcagcgc cgcccaacca
     3841 ttgatggggg tcagcgtcga aatataaatc agcgcaatca aactgtagaa caacaagcat
     3901 agccctatgc gggtaaaatg ctttttctgc gcgctttttt caccaaaaaa tagataaccg
     3961 gagatcataa agaacaaagg cacgcaagct cgagaggccg aattcagcaa gttggcaatg
     4021 tcccaattca cttctcctac ctgcgcacca cgggtgacgt aataagtcgt ggcatggatc
     4081 atgaccacca taatgcaggc gacggcgcgc aagttatcaa tccagccaat cttattggtc
     4141 atgcatactc tctatcacct gtttttatac ttaaaagcgc ctagttattt aggacgccaa
     4201 taatcaggct gcaaacaata acgtaaattc ggctgatacc caaagtaaat gaaacggcat
     4261 caagcacgaa gggtaattgt tgccataacg ttatattgac ggcaaaatag ccgtcctaac
     4321 atgctctgac tgtacatcct gcctgagcag ttcccttttt tatgtttatt attaatagct
     4381 taacttatgc aaacttcatt ttcacccgcg acgcgcttag gtcgacgggc gcttttattt
     4441 cccctgtgtt tggtattatt cgaatttgcc acctatatcg ccaacgatat gattcagccc
     4501 ggtatgctgg cggtggtcgc cgattttaat gccagcgttg agtgggttcc gacttccatg
     4561 acagcttatc tggctggcgg gatgttcttg caatggctgc tggggccatt atcggatcgc
     4621 cgtgggcgtc gcccggtgat gctggttggc gtcgcatttt ttgtggtgac gtgccttgcc
     4681 atattattgg tcacgtctat tgaacagttt atcgccatgc gcttcctgca agggatcggc
     4741 ctgtgcttta tcggtgctgt cggctacgcc actattcagg aatcatttga agaagcggtc
     4801 tgtattaaaa tcaccgcgct gatggcaaat gtggcattaa ttgccccgct actcggcccc
     4861 ctggctggtg ccgccttgat acatgtcgcc ccgtggcaat ccatgtttgt gatatttgcg
     4921 gtgctgggtg cgatttcatt tgctggatta tggcgggcaa tgccagaaac cgcctcgcgc
     4981 aaaggggaaa aactgtcggt aggggcgatg tggcacgatt ataagcaagt gctcgctaac
     5041 cgccgtttcc tgtgcggatc gctggcgttg ggctttgcca gcttgcctct gctggcatgg
     5101 attgcgcaat cgccggtgat tctgatcagc ggtgagaaat tatcgacggt ggaatacggc
     5161 gtgttgcagg tgcccatttt cggcgcactg attatcggta acctaacact ggcgagactg
     5221 agcggcaaaa aaagtattcc gcagcttatc cgctatggcg caggcccaat gattattggc
     5281 ctgatgattg ccgctggctc gaccctctat tcatctcatg cttatttgtg gatgacggcc
     5341 gggttaagtc tgtatgcctt tggtattggc ctggcgaatg ctggcttggt gcgcttgacg
     5401 ctgtttgcca gtgacatcag taaaggcaca gtgtcggccg ccatggggat gatcagtatg
     5461 atggtcttca ccttggggat tgaattcgcc aaagtggcgt atctgtgggg caacagcgga
     5521 atcttcaatc tgttcaactt aatcagtggg ttgctgtggc taggtttggt gatgattttt
     5581 atccgtcgcc agccagattc attggctaca gagtaatatt gccgaggcgt gtcacttaat
     5641 atctgttaaa cagacttaat gcacgcctcg ctcagaagct caattcacag cagaaaacag
     5701 ccccctgtcg cgcaggaaat ggtcattacc ccggcggcgg gtaaacccac tgcggtcaaa
     5761 gaattcaagg atttgaatcg ccagtttgcg gccaatgccc aatttgtcgc ggaaatccgc
     5821 tgcactggca ctgccttgac tggcgtccag ctcacgaatt aaatcagcaa actgctcaat
     5881 acgttggctc agatagtagc ggtcagggac aattgccgtg atgtagccca gttgcgcggc
     5941 tttgcgtaat aagctgcgca tctcgccttc atccatgact aactctgtgg ctaaatcacg
     6001 cacccaccag ggatcgtcag agaaataggg ggcaacctgt tgccatcgtg cttgttcttg
     6061 ctcggtaaat cctaatccat gttcgggcag gtgcagccag ccgcgagtat tctttagcgc
     6121 gccctgtgtc agcaaatcat caatcaaacg aaacactaaa gtttcatcca gtgtcggcaa
     6181 tgccatgcgc cgcaaacgcg cccgacctaa ccctaactga tcattatgtt gctgatgata
     6241 aaggcataaa acatgcaata aggtttgttg cgcttgttgg gcatgagggc tagacaatgc
     6301 aatatcaccg gcaataacgc agtcagtacc ggttaataat gcagccatat catggctact
     6361 cagctggcgc gcccaactga acttacccac agagagcggc ccttgcgcca aatgcagccc
     6421 cagcacttca ctgtctgact tcgcctgcgc taacgcggtt aaccacgcca aaaatgccgg
     6481 ttgccgctta ccgcgttttg gcaccgccag gtggatgacc cgtgcagcac ccaaggtctt
     6541 tttcgcggcg atatcccgta ggatcagccg atcattctca gccagccaca gaggggtatc
     6601 cagcaatatc tcagccaata tccattgggg tttatcgccc tcctgctgag aactgttaag
     6661 cagtgaaaag cgcccggtaa tatggctggc agcatgatgc aaatgcagcg gttgccaatg
     6721 ctgtatcggt tcatcggcat cgacaataac caaaacccga tcaacggatt ctggtggctg
     6781 ttgcgctaat agccagtcgc cgcgatcgat ttgttgtttg ctaatatcgc cagtgatatt
     6841 cagcgcaatg cgctgccccg cttgtgcttg ctgcgtatct tggttttgag cgtggatgcc
     6901 ccgaacccgc accggacaat cgctgccagt gagccatagg gtatcgccca ccgcgacttt
     6961 acccgctaac gccgtccctg tgaccactaa accggcacct ttcacactga atgcgcggtc
     7021 aatcgccagc ctaaaacgcc gctgtagccg gctattattt tcatcttgct gatgacattg
     7081 cgccagatgc tcgcgcaatt cgctgatacc gcgatcggct gtcgctgccg tgacaaacag
     7141 agtgacttgc tctgctggcc agccttgagc tgacagttca gccatcactt gctggcggac
     7201 ttgctcaatc cgctcgccag atgctcggtc agctttagtc agtgcgaccg tcaatgtcgg
     7261 gtggcccgtc agccgtaaaa tcgccagatg ctcgcgagtt tgcgccatta cgccatcatc
     7321 acacgccacc accagcaaag cgtgatcaat gccgcccacg ccagccaaca tattggcaag
     7381 aaatttctca tgtccgggaa catcaataaa cccaatgata ctgtcatccg gttgtggcca
     7441 ataggcatag cccaagtcaa tggtcattcc gcgctgcttt tcttccggca agcggtcagc
     7501 attgacccca gtaatcgcct gtaaaagcgt agttttaccg tggtcgacat gtcccgcagt
     7561 tgcaataatc atggtgccag ctccctgagc aacgccgttt catcctccaa acagcgcaaa
     7621 tccaaccata aacgcccatc agcgacgcgg ccaatgacgg gtttagccaa tccacgccag
     7681 cgtgctgtga gtgcttccag cgcacttcca ctgccctctt taggcataaa tgttaccgcc
     7741 caactgggta aacggtctac aggtaatgaa ccactgccaa tctgcgacca acatggctca
     7801 gcagccagtg taaaatccgc accatagctg ccattgagtg cagccaacac ccgctgtgcg
     7861 ctctcggcaa tattctgcgc cgagcgcgtc agtagccgca gggtcggtaa taactcactc
     7921 aagcggtcgg gctgctgata gagacgtaaa gtagcgtcca gcgccgccaa tgtcatttta
     7981 tcggcccgca atacccgctt gagcggatgc tgctgcaatt gctcaatcca ctgtttttta
     8041 ccgagaatga tccccgcctg tgggcctcca agcagtttat cacccgagaa agttaccaaa
     8101 tcgacacccg ccgcgatcaa ttgctgtggc atcggttcag ccggtaagcc gtagcgggtc
     8161 atatccacca gcgaaccgct gcccagatct gtcgcggtcg ggatagcaaa ttcatgcccc
     8221 aaagccgcca attgttgctc cgtcactgag gccgtaaaac cctcaatgct gtaattgctg
     8281 gtgtgcactt tcatcagcag gccggtgtgt tcattaatag cctggtggta atctttcagg
     8341 tgggtgcggt tggtggtgcc gacttcaacc agctcacaac cggcctgacg catcacatcc
     8401 ggaatgcgaa aagcaccgcc aatttcgacc aactcgccac gagaaaccac gacttgcttc
     8461 ccagccacca tgactgtcag catcaaaaac accgcagcag cattattatt gacgatgcag
     8521 gcatcttccg ccccggtcag ttcgcagagc aaatcggcca ccgcgcgatc acgatgaccg
     8581 cgaacggcat tactcagaga atattcgagg gtaaccgcgc cacgcatggc gtcagtcacc
     8641 gcagcaatag cggattccgc taaaggcgct cgccctaaat tggtgtgtaa aaccgtgccg
     8701 gagaggttaa aaacgggttt caatgcgggt tgacgttgat ttaatcgctg acgtaaagcc
     8761 gctggccagt ctgcgcacca atcagccaat gtatggaatt gaccaatata ttcacgggcc
     8821 tcagcctgca tcaaacgcag ggtttcagtt aacagagctg cgccatattc gtcaagcaaa
     8881 ggggccattt ctgacgaccg caacaagctg tctatggcgg gtaactggct gtaaagatga
     8941 tgggattctg cgctcatagt cactcagcgg gggttattaa atgctacggg aactcatatt
     9001 atatatgact caccgggaag ttgactcccc ggggaactta ttcactcgcg accctattga
     9061 ctcgaaaaaa gttattcacc tggaaacacg aacggattaa tactgctgcg ggcaaaacct
     9121 tcaccttcca tcttggcatc gagaatcagc gaggctaaat cgtcggcaac tgcttcgacc
     9181 atcgggtctt tttcttgata taagattttc aggtaagtgc cacaatcgcc acaactttct
     9241 gctttcacag cagccaattc gctgtccagc gaccagtagt tcaaatcacg agtttgctcg
     9301 caattactgc atttaatccg caccacatgc cactcgctct cacacaaatt gcagtgtaaa
     9361 taacgcaaac cgctgtgggt gccaatgtgt accacactgg agacaggaat actgccgcat
     9421 accgggcaaa attggcgatg ttcaccatac tcagcccgcg ctttaccggg gatttggctg
     9481 gccatttgcg tccaatacaa ggatagcgcc gcccagataa agggcgcttt ttcgctacct
     9541 acattggcaa attcgcggtt taacagcgca tcggcgtcca actccagctc atgtaccgat
     9601 gccttatcca gattatccag caccgctgca atagggtcgg gcgcatcagg gcgtagctcg
     9661 gcaatgagcg ctgacaatag cttgcgccag tggtcagtac ggggaaaaac gcttaaatcc
     9721 agcggcggtt taccactggc cgcggattgc gccaactccg cttgcatgtc caacaccagc
     9781 gggtggtcat gcagtgcttt ttgctgcgcc tgtgtaattt tagccgcaaa atccagatag
     9841 tccgccagcg gattatccag cgctagctgc tgcaaacgct cggtacgccg ggtatacagg
     9901 ctttttaaat tcgcgaaaag taacggcggg atattccccg ccgtcgtgcc tttttcgctc
     9961 tgttttccta attgatcttt agggacaatg cgaatactca tcagggtttc tcttcctgtt
    10021 tgttctgaag ttgccttttg gcgttaactt cacgatacca acgcggatgg tgctttttag
    10081 cccatgctgc cggtacccaa ccttccacca tcgcggtaat cgtgcctttc acccacaggg
    10141 cggcatagat atgcaccata atgacaataa tcaatcctac cgccgccagc gaatgcacca
    10201 gcagcgccag gcgaatcagt gggatcggga aggagggcgc aaagtaaggt cgccaaatca
    10261 ccacgccact ggccagcaat aacaccaggc tgataatagc agcccagaat acgcatttct
    10321 gaccaaaatt atagcgcccc gtgtcaccca cttcctcatt catggcgatt ttatggatat
    10381 ttttagccca ctccaggtct tccttgttga tcaagttatg tttccagtaa cggaaaaaca
    10441 tgatcaggaa ggcggcgaac ataatcaccc ccgcgaaggg gtgaaggatg cgcgccaact
    10501 gcggcgtacc aaaaatattc atcagccagt tgaatgacgg gaagaagaac cccaaaccac
    10561 tgatggcggc caacataaaa caaaaggcca ctatccagtg gttgattcgc tccggcgcac
    10621 tgtagcgctg gatccgcttt tcttttttca tttccgcgtc tccccgtcgt ctgagtgttc
    10681 agcggtggtt ggctcaggag ccttggatgc cgtatcagaa ggggtggaat ccgatttatc
    10741 gtcttcgtcc tcctcttcct caacccggtt cgggccgacg cccacataat ggaagatact
    10801 ggcggcaaag gtcgcagcaa agccgatcgc cgccagtggt ttccagatac ctttccagaa
    10861 agtgactgtc gggctgatgg tcgggttctc cggcaagcca tgataaagct gaggtttatc
    10921 agcatgatgt agaacataca tcacgtgagt gcccccaaca cccgctgggt catataaccc
    10981 ggcgttatca aagccacgcg ttttcaactc actaacccgg cctgcggcca cttctttcat
    11041 cgcctcttta gtaccaaagt gaatcgcccc ggtcgggcag gttttcacac aagccggttc
    11101 ctgacccaca ccgacacgat cgacgcacag agtacatttg tacacccggt tgtcgtcttt
    11161 attcatgcgc ggcacgtcaa atgggcaacc ggcgatacag tagccacagc cgatacagtg
    11221 ttctgattgg aaatcgacga tgccattcgc atactgaatg atagcgcctt ctgacgggca
    11281 ggctttcaaa cagcccggat ccgcgcaatg catgcagcca tccttacgga tcagccactc
    11341 cagcttgccg ctctcttcgt cttcaacttc agagaagcgc atcaccgtcc atgacttggc
    11401 ggtcaaatca gcggggttgt catacacccc gacgttatga cccacttcat cacggatatc
    11461 gttccattcc gaacacgcca cctgacaagc tttacagccg atacaggtgg tgacgtcgat
    11521 aagcttggcc acctcttcct gatgattacg tgcctgtggc ggcggcgtaa gggagttggt
    11581 gccggagcgc cggataatgt cttgagtttg cagtgacata ggttatctcc gttacacctt
    11641 ttccacgttg accaggaacg ccttgaactc tggcgtttgc gtattagcat caccgacaaa
    11701 gggtgtcagg gtattggcaa taaagccttt tttcgctacc ccttcataac cccagtggat
    11761 cgggatacca atagtgtcaa cttcttgccc atgaacattc agcgtgcgaa tacgtttggt
    11821 caccaccgcc ttggctttga tatagccgcg gttggaactg actttcacgg tatcaccctg
    11881 cttaatgcct tttttcgccg ccagtttctc gccaatctcg ataaactgtt ctggctgcgc
    11941 gatagcattg agcagcgcat gcttagtcca gtaatggaaa tgctcggtca gacgataagt
    12001 ggtaccgaca tacgggaact gctcatgaga acccatggca gccaaatcgt ctttaaagac
    12061 gcgtgcggct gggttggata tcacattcgg atgcagtggg ttggtgccca gcggcgtttc
    12121 gaacggctca taatgttccg ggaacggccc ttctgccatt ttgtcgatgg caaacagacg
    12181 gcccatgccc tctggctgca tgataaatgg cccaacatca ctgcccggtg cggcggcgct
    12241 gtaatcggga atatccacgc ccccccattt agctccatcc cattccaaca gctggcgttt
    12301 cggatcccaa ggtttaccct gtgggtcagc agacgcgcgg ttgtatagaa tgcggcggtt
    12361 aagcggccat gcccatgccc agcccaaggt attgcccaaa ccggatgggt cagcattatc
    12421 gcgccgtgcc atttggttac cggctggagt ccagctaccg gcaaaaatcc aacaaccact
    12481 ggcggtggtg ccgtcatcgc gcaagtgagc aaaggtgctg agctgctcgc cttttttgac
    12541 cagcactttg ccatcggcat cggtgatatc ggccagcgct ttaccattgc tttcctgtgc
    12601 cacttcttct ggctctggat tatctggcgt caggtaatcc caagtcatat tgagcacctg
    12661 ttctggcact gcaccccctt cccggcggta catatcacgt agacgactaa agatacccgc
    12721 caaaatggca ccgtcgttca atgcttcgcc cggtgaatcc gcacctttcc agtgccattg
    12781 cagccagcgg ctagagttaa cgatggaacc gttttcttca gcaaaacaac tggatggcaa
    12841 gcggaatacc tcggtttgaa ttttcgatgg atcgacatcg ttaaattcac cgtggttttg
    12901 ccagaaattc gaggtttccg tattgagcgg gtcaatcgtg atcaggaact tcagtttcga
    12961 cagtgaggcc actactttgt ttttattcgg gaatgaagca actgggttaa agccctggca
    13021 aatatagcca ttcactttgc cctgcgacat catctcgaaa tactgcaata cgtcgtagcc
    13081 tttatcccac ttcggtaacc aatcgtagcc ccagccgttc tctttctggg cgttgtcacc
    13141 gtagaaactt ttcatcaggc tgacgaagaa tttcgggtaa ttgctccagt agttaacttg
    13201 gcccggcaac agggttttcg gcgtgttggc cttcaggtaa atatcaatat ccggctgttt
    13261 ttctgacggc aagttcaggt agcccggcaa gctttgcgac agcaagccca ggtcagttaa
    13321 gccctgaata ttagagtgac cgcgcaaggc gttaatcccg ccccctgcca tgcccatatt
    13381 gccgagcaac aactgaatca tcgccatagt gcggatgttc tgcgcaccaa ctgagtgctg
    13441 tgtccagccc agcgcataca ggaatgtggc ggttttattg gacacactgg tttcggcgag
    13501 atattcgcaa acctgcaaga aatcggcttt tggcgtaccg caaatgttgg agaccacatc
    13561 cggcgtgtaa cggctgacgt gttctttcag caagttccac acacagcgcg gatcttgcaa
    13621 ggtgacgtcg cgtttcgcaa agccgttttc atccaactgg taattccagc tggttttatc
    13681 gtatttgcgg ttttcggcgt cataaccact gaacaaacca tcgtcgaaag tatagtcttc
    13741 ccgcaccagc aagctggcgt tggtataagc ttcgacatat tcgcgattaa ttttgttgtt
    13801 ggtcatcaga tacaacaaca cgccggacag gaacgcgata tcgctaccgg atcggatcgg
    13861 cgtatagaag tccgccaccg aagcagtacg agtaaagcgc gggtctatca ccagcagctt
    13921 ggcattgttg tggattttgg cttccatcgc ccagcggaac cccaccggat gcgcttctgc
    13981 cgcattaccg cccatgacga taattaagtc tgcgttcttg atgtcaaccc agtggttggt
    14041 catcgcaccg cgaccaaatg ttggagcaag acttgctacc gttggtccgt gtcagacacg
    14101 tgcttggttg tctacggcaa gcatgccgag agcgcgacta aatttctggg tcaaataacc
    14161 cgtttcatta ctggatgccg aagcacacaa cataccggta ctcagccaac ggttgacggt
    14221 cacacccgca tcgttggtct taatgaaatt agcatcccgg tcttctttca tcagcttggc
    14281 aatgcggtca aatgcatcat tccaagtgat tcgctgccat ttatctgaac ctggcgcgcg
    14341 atattctggg tatttcaagc ggctttcact gtgaatgaaa tccaccagcc ccgcaccttt
    14401 agggcacagt gcaccacggt ttaccggatg atctgggtcc ccttcaatgt ggaaaatact
    14461 ctctttggcg tttttagcac catcgccgag gctatacatc aaaagcccgc aaccgacgga
    14521 gcaatatgtg caggtattcc gcgtttcacg ggcgcgcagc aacttataat tgcgcgtttc
    14581 cgctagcgcc actgacggcg taaagccgag tgccgcgacc gtggttcctg ccataccgcc
    14641 agcgcagatc ttaaagaact gccttctgct gacctgcatg ggtctctcct tcattcattg
    14701 tcacattgta tgaatttaaa attcagttcg cgcttccctc aacaaaacca gaagcgctaa
    14761 aatcgctaaa gcgatatcac ctttatcggt gtgggataca ttcctattga aatggaatca
    14821 tacccatacc attcttaatg tgaatgttac cacattgtga ttatgggtta taactttcag
    14881 ggccgcatag tgagccagat caaaccttca gatattgacc tttcaaccgg aatttgcggc
    14941 gcccgacagc ttaacgtgct acagcgccat caaatggccg agccgcagtt ggattggttg
    15001 gcagaggaag taccggtagc tctggtgtac aacggcattt ctcatgtggt gatgatggcc
    15061 acccccaagg atttagaggc tttcgcgctg gggttttcgt tatcagaggg aattattagt
    15121 acgccgcaag aaatctacgc cattgatgtt aatcctggct gtaatggcat agaagttaac
    15181 attgagttat ccagccgccg ttttgtcggt ttaaaagaac gccgccgggc gatggctggc
    15241 cgcactgggt gtggtgtctg tggtattgag caactggacg atattttccg cccaattacg
    15301 cccttgccgt tcacgcaatc ttttgatttt aatcatttag accatgcact tgcacaactc
    15361 aaacaggtgc aaaccgtggg ccaactgacc ggctgcaccc atgccgccgc ctggattaat
    15421 cctcaagggg aattattagg tggctgcgaa gatgtgggcc gccatgtcgc actggataag
    15481 ctgctcggga ttcgagctaa acagccgtgg cggcaaggtg cagtgctggt ttccagccgc
    15541 gccagctatg agatggtaca gaaagccgcc atgtgcggtg ccgaaatttt atttgctgtt
    15601 tcagctgcca caaccttagc ggtggaagtc gctgagcgct gtaatctcac cttggttggt
    15661 ttcagtaaac ccggtcgcgc aacggtatat acccacccgc agcggattaa cacataaaaa
    15721 ccacacaatt tgtacggcat tgataatcat tttcaatatc atttaattaa ctataatgat
    15781 ccgaatgctt acgcggtgct tacttttttg cgccgcccta cacctacgga gacgatgatt
    15841 atgagttact cactgccatc cctgccttat gcttatgatg ctttagaacc ccacttcgat
    15901 aagcagacga tggaaatcca tcataccaaa caccaccaaa cctatgttaa caatgcaaat
    15961 acggtgttgg agagcttccc tgagctggct aaattcagtg ttgaagatct gatcaaagat
    16021 ctggacaaag ttccggcaga aaaacgcacc tttatgcgta ataacgctgg cggccatgct
    16081 aaccacagct tgttctggaa aggcctgaaa ctgggcacca ctctgaccgg tgacctgaaa
    16141 gccgcgattg aacgcgactt cggcagtgtt gacagcttca aagaaaaatt tgaacaagct
    16201 gcggcaacgc gtttcggttc aggttgggct tggctggttc tgaaagacga tggcaaactg
    16261 gctgttgttt ctactgctaa ccaagacagc ccgctgatgg gcgaagcggt ttctggcgcg
    16321 tctggcttcc cgattgttgg cctggatgtg tgggaacatg cttactatct gaaattccaa
    16381 aaccgccgcc cagactacat caaagcattc tggaacgtgg ttaactggga cgaagcagcc
    16441 gctcgtttcg ctcaagctaa gtaattctca gctagccatt ctgcggcttc aagtccgcag
    16501 agtataaagc cgaaaaccat gccagcaagg ccctcttgct ggcatttttt ttgctaaagt
    16561 ttcgccaatt tctgccgata gattgcacaa gagggatact gacatttatg gcatgaatct
    16621 atgaatcatc agccctaaat atcgcgacaa aaacgtgaga aaaagcactc ttgccaaggc
    16681 gacctcacgc ccagccctcc atcattattc taataattag acctacccct attcacctac
    16741 actgattaat ttgcatcaga aacaccgtat aacggagcag aacatggcag gatttagcaa
    16801 aatttttggt aattttgaaa acgtgaaagt cggtaaaaag ctgggattaa gctttttcct
    16861 gatgttgttg ttagttggga tcatcgcggg taccactgcc tatcatttct ccgtcattga
    16921 agaacatgct tataaagtcg acttgagtta caaaattaat gatgaagcca accaggcaaa
    16981 atataatcgc gcgctatatg aacgcaccta tgatttgaaa tatatcgaag aaaactcaga
    17041 acatatcaat aagataaaaa gtctattaga ccaaagtgaa acacttggct ggtcggcaga
    17101 taaccgtaaa acgatcagta gtatttccga tgtggtagaa gaatatctgc aacaacaaag
    17161 taactttgtg aatgcagtag cccataaaga cgatgtgcgt aaaagctgga atatctctga
    17221 aactcaaaag aatctcaatg agttacagca aagcttgctc aatgagggcg cagataccaa
    17281 cacccagatt ctactggcgg aaatgaacca aaagttgatg accgtgcgct ataacgcgcg
    17341 gggtttattg ctggatcgca accaagatgc agaatcttcg ttgataacct cgatcaatat
    17401 tgccaacagt gcggcgaatg ctttcatgcc agtgttatcc gctgaccaac aaaagttatt
    17461 agccccggtt atctccagcc tcagcgccta taaagacaat gttctggcct atttaccggc
    17521 ttatcaacaa gagttggaag tcggtaaagt gatggaagat aatgccaatg aattgaataa
    17581 gttggcgacc cacctgttca cccaagaact gcaaggcacc cacgacgaaa tcgataatgc
    17641 acaattgcag ttaactatta ctgtcattgc cgctttgcta tttggcttac tgatttcatg
    17701 gcgcatgacc cgccagatta ccgtgccact gcgcaccaca ctggcgatgg ctgaacgcat
    17761 tgctaacggc gatttaaccg cagagaccac atcaactcgt accgatgaac tgggcctgct
    17821 gatgaatacc gtcgcccgga tgaatgaaaa cctgcgcgcc atgattgatg aaattcgtat
    17881 cggcgtcagt caggtgtctc atgcttccgg cgagattgcc gcgggcaata ctgatttatc
    17941 ctcccgcacg gaacaacaag ccgccgccgt agaagaaact gccgccagta tggagcaatt
    18001 gaatgccacg gttaaacaga atgccgataa tgctcaccac gctaatcaac tggccaccga
    18061 ggcatcacaa actgcgcaac aaggtggcaa gctggttaat gatgtggtgc gcaccatgaa
    18121 tgatatctcc ggcagctcta aacgcatttc tgaaatcacc tcagtgatta atagcattgc
    18181 tttccagacc aatattttgg cactgaatgc cgcagttgaa gcagcacgcg ccggtgagca
    18241 aggccggggc tttgccgtgg tcgccagtga agtgcgtaat ttggcgcagc gtagtgcaca
    18301 agcggcgaaa gaaattgaag ggttgattgg cgagtcggta tctcaagtca atgctggtac
    18361 ctcgctggta caaaatgcgg gtcaaactat ggaagatatc gtccgctccg tcacccatgt
    18421 gcgcgatatt atggcagaaa tcgcctcggc ctctgatgaa caaagccggg gtatcaccca
    18481 agtcagccag gctatttccg aaatggacag caccactcaa caaaacgccg cattggtgga
    18541 agaatcggcc gcagctgctg actcactggc tgaacaagcc atcttactgg agcaagcggt
    18601 cgcggtattc cggctgtccg aagcagaagt tgaaactgtt caaagcaata ctagcgcctc
    18661 acgtgtagcc acaccgcgcc cggccccaga cgctagccgt aatgatcagc aggataattg
    18721 ggaaactttc tgattattta tttcgagtac agacaaggag aatagtcagt caaaacaata
    18781 ttgccaagga cggcaaactt atatgggaga tatgcttagc atatatcaag agtcatacaa
    18841 atccgcaaaa accgggcagt ggctatgcca cacacccggc tttatcgaaa gtcgcaatca
    18901 gaacgctttt ttggcgtaac cagtcacttc tttcaggccc atctcgcgac ctaatgctgt
    18961 cattgggtga accaccacaa tgccgcgcac tgctttcttc aaagtgccca tatccgcttg
    19021 ctctttcttg gtaatcgctc ggctgaatgg cagttgcgcc agcttttggg cttcagcact
    19081 caggttttta acccgcactt ctttcaaacg ctgtatttca gcagccagtt tctctttttc
    19141 tttcatatgc tgtgcgatta actccatatt accctgctgt ataacagccg gatctttatg
    19201 gttcagcgca tccagcatat cgcttagacg tttgatttct gcatgttctt tcatagtatt
    19261 ggcccgtaca tgccgctgat gggcacgata tttcgctaaa gttggagata agatagcact
    19321 gattgtgcat caagatggat agtgtatcag gatgtaggcc tttcggcagc agcctcctgt
    19381 actggttgcc actgcattcc ggcgggtaaa ccgctaattt cacatgcaac cgcccctaac
    19441 cgctccagcg ccccagtata gcggctattg aatggataac agcacgatag gcgaaatgca
    19501 ttgcgatacc ggccactggg tgaataaagc gtccccggcg tcaagcaaat ctgctcttgc
    19561 agcaattgat gaaacagcgc gacagtatcg acgctatcag ggaattcgac ccaaaataca
    19621 aacccaccag ccggctgtgt cactgtagtt ccccgcggaa aatagcgggt aatcagttgt
    19681 tgagcttgct gaacctgctg cgcataacgg cggcgcaaac tgcgcagatg gtggtcatag
    19741 ccgccagact caaggaacag tgccagtgtt tccgacaaca gcatcggctc cgccatcgac
    19801 gataccgctt ttagcttgtg caacgcttct gcgaagcggc ccccatcaat ccaaccaata
    19861 cggaaatccg gtgccagcgt tttggtgaag ctggaacaaa acagtatcca gccgtcacga
    19921 tcgaatgctt taactgccgg agataacgtc gagccaaatt gaatttcggc atataaacca
    19981 tcttcaatta atggcacttg atgatcgttc atcaactgcg ccaatcgttt tttcgcagtg
    20041 aggggcatgg tataacccat gggattttgc accgtcggca tagcaatcag tgcattcagc
    20101 cgcccttctt tcagcaataa ttccaacaca tccaatgaga gcccttgctg cgggtcagtc
    20161 ggaatctcca cggctttcaa gccaaggcta gctaataagg gcatcagata gaaataagtc
    20221 ggcgactcca gcccgacaca atcgcccggc ttggtggtca cccggagcgc taattgcagc
    20281 gcctccatac atccatgggt aatggtgata tctgccggat ccgccaacat acccaacgtc
    20341 atcgcgcggc gagctatttg ctggcgtagg cgctggttac cggggggcag cgcatattga
    20401 ctgatcaact gcggctgacg gcgtaacaaa gaagccataa tgcggcccag tttggcgctg
    20461 ggatagaaat cgccagtctg cgggcaggcc aacgagatat tggtaaagtg cgggttttgt
    20521 tgtgcggcaa agactgtatc aatcaaatcc agcacttcat ctaccggctt ccccactgtg
    20581 gcggttggca ccacggcggt tgatgggcta cagacataaa aacccgactg cgggcgagcc
    20641 tcaatcaggc cacggtcttc caatgtgcga tacgcggcga ccacagtatt gatactcacc
    20701 tgatgactct gcgcgtaact ccgcaccgaa ggcagacggc tccccgccag aagactgcca
    20761 tttttaatgg cttgcgccaa attgtctgcc acttgtaagt agcgaatttc attcataaca
    20821 agggacatgg tgacagttct ccacaggatc gatgggtaca gtttggatac acttaaactg
    20881 tacccataac aatagataac ttctgcttct gacgccatca cggattgatg tttatgctaa
    20941 atctcttggt catacgcttt ttgaaaaata agaaaatcgg ggtttatatt atgttagaca
    21001 gcgctttcat cagttacgtc accgtcatgt cgatcacgcc cggcccgaac aatctgttgt
    21061 tggcagcatc cggcgttaat tttggcttgc gccgcacttt cccgatgatg ctggggatta
    21121 cctttggttg tgcgctgcaa tgcgcgttaa tgaccacact gctggccttt atcctcagtt
    21181 gggtgggcgt ggttcgcttg ccattggtga cattgggcgg cggttattta ctgtggttat
    21241 cctggaagat ttttaattcc ggcaccccca atgcgcgcga cagcgagcag ccaatggggt
    21301 ttattcaggg ggcattattt caagcaatta atccaaaagc ttggttgatg gcaatgaatg
    21361 tcgccatctt attcactcca cgtgaaggcg caacactgag ccatactttg ctgattgtcg
    21421 gtggtttcgc tctattaaat ctgccttgtg tggcggtttg ggcggtgatg ggtgatcaat
    21481 tgcgtcatgc gctgcgcgtc aattggaagt tgcggctatt taatggtgtg atgggcggct
    21541 taatggcaat caccgcactc tggctattgg cagatgagtg gttaaccgca ctagcataat
    21601 taggcgtggc cgagtggtga gagcttagaa acttgttttt gactgatacg ggagagtaat
    21661 tcagtaatcg atagcaccat ggtggagcgc accatttgct gataacgctg gcgttgcatg
    21721 gcaatcagcg aagcatctgc ttcatccggg cgtaagaatg tcggaactgg tggcaattca
    21781 gccacacaat gcaattcacc aaatggcccg aggatttcgt catcggtaaa gcgatactcg
    21841 gtgccatcat ggtttagctc ttcacgcagc gccattaata gctcggcatc ttcatactca
    21901 tgccgggtta tgacgcccaa agcataaacc aacttcaatc gtactgatag ctcacccaac
    21961 ggcccatccc cgaccagcaa tggctccacg gcatatttca ccgcatagtc atctttacga
    22021 aaaacctgca ccacgagaat gtttaatgct tctgccaata agtcgacagc agccatcaag
    22081 aaactccgaa cggtcttccc cgcgttcaga tgttcaagta cccgattctc aaatgcctgt
    22141 gttttttcaa tcattgtttg tcactggggt tgcagattat caggctatca aaggataaat
    22201 accgcgtaat ccgacacggt atttatcccc gtcatacttc aagccgcatg tgcgttggct
    22261 acattcaatc acccgaatca ctaacaacag taagctcatc gggatcctct gcttgccgcc
    22321 ttcctgcaac ttgaactatt tagggtatat cccctaacga aacggaatta gtgcgccagc
    22381 ttgtcctgca tggcgttata cacactcacc gcctgttcca caacctcgct atcagctggc
    22441 agaccggaaa tttgagcaag agtggctttt ggccctaatt tagccagtaa ttcaaccagt
    22501 tcctgcgctt gcggatcttg ctcactgcga taactcattg cggcagcaat gccggtcacc
    22561 aggttattat gtggcaattg atattccaac gtccccaaca gcggcttgat caatcggtca
    22621 ccggcactca atttacgcaa tggctgacgg ccaacgcgct caacatcgtc atgcaggtaa
    22681 gggttttcga aacgggagag aatcttatcg atataagccg catgtttctg cggatcaaaa
    22741 gcatagcgct tgatcagcac tgcgccgctc tcttccatcg cgccctttac tgtctggcga
    22801 acggcgggat caagaatggc atcacgaatg gtttggtgcc cggcaagctg gcccaaatag
    22861 gcggtaatgg catgcccggt gttcagcgtg aagagtttgc gctccacgaa ggccatcagg
    22921 ttgtcagtca gttccatacc ggcgatttgc ggtggctgcc ctttaaactg ggtaccatca
    22981 acaatccact cgctgaatgt ttctacggtc acggccagaa tatcagtgct gcccgcttct
    23041 gatggcggca cgatgcggtc taccgcagaa tcaacaaaac caacatgttg ctccacccac
    23101 gcctgctcac tttctggcaa ggcagcaaaa acatgttgtt ttaactggct ggtgccgcgc
    23161 accatattct cacaggcaat aatattcagt gggcgggtat taccttgttg atgacgggtc
    23221 accaaacctt gtgccacggt gccggcgatg cgagctaaaa tttgtgggcc aaccgcggtg
    23281 gtgacaatat cagcatcagc aatcagtgcc accacttccg ggctaccact gttcactgcg
    23341 ctaacatttt tcacttcttc aacacgggct tgctcaccca ccacattaac ctgataactc
    23401 ttacgcttat tcagttcatc caacaacggc tggttcacat cggcgaaagt gagttgtgca
    23461 ccggcatcag caagaagttt accaatgaag ccccggccaa tgttacctgc gccaaaatgt
    23521 aatgctttca tattcgttac ctttaactgt gtggctgtga aagggccgcg tactccccac
    23581 ggccctatac tcgtcatact tcaagctgca tgtgcgttgg ctgctatctc caacccgaat
    23641 cattgactcg agtcaactca tcgggattaa tgaggctcac cctgcgggct agcataaatg
    23701 ctgttcaaat cggttcctga ccaatttgtt attcgcttgc cgccttcctg caactcgaat
    23761 tatgtaaagt atgttcagtt acaactgggt gacttttcca cccagtgact ttttaccgcc
    23821 aagctatttt ttaccgccta ataagtccaa cacttcttgt acgtcagtcg ttttacttaa
    23881 gcgctcaatg acagagtcat catccagcgc gttggtcagg ctggtaatca catgaatatg
    23941 ctcattgtta cgggcggcaa taccaatcac caagcgcgcc acttcgtctt cttcttcgcc
    24001 aaaacgtaca ccctcagggt attggcagaa caccacaccg gtcttcagta cgcggtcttt
    24061 agcttcaatg gtgccgtgtg gtacggcgat agattcgccc agataagtgg agctcagttt
    24121 ttcacgttcc aacatcgctt caacatattc tggctcgaca taaccgcctt ttaccaactg
    24181 ctcaccggcg aagcgaatag cttgctcttt atctgtagca tgttgattga gaaaaatatt
    24241 tcccgcactc agtttgaaca ggttggcttc tgatggctca aagctatcat ccagcgtttc
    24301 aatcactttt tgtgtggtcg ccgtcgcgtt actcacttcg actaaacgtg ccgtcaggtt
    24361 ggtatacagc tggctgtcga ggaagttagt cagcgagata tgctgtgctt gcggtgcatg
    24421 acgcattgct cgctcagtca aatcacggtg cgtgataact aaatcaacat cttccggcaa
    24481 gttattgatg gcgcagttcg tgaccgagat gtgcttcagg cccgcatctt gcactttctt
    24541 acgcaacaca ccggcaccca tcgcactgga acccataccg gcatcacagg caacaatgat
    24601 tttccgcaca gtgctcaagt cacccgcagc cgctgctgca ttggctgctt gtgcgccttt
    24661 agattgcgct ttcatgtct
//
