LOCUS       NZ_KE386488.1          25453 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KE386488.1 Rikenella microfusus DSM 15922 RikmiDRAFT_RMD.2, whole
            genome shotgun sequence.
ACCESSION   NZ_KE386488
VERSION     NZ_KE386488.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:02:52
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1510170
            Orig. end    :: 1535623
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25453
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1520170:1525623]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15453
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..25453
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25453
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="3"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(500..3172)
                     /locus_tag="ctg2_1205"
                     /transl_table=11
                     /translation="MTPFFLKTLRGTALCAALAVGGQTLHARQTSEGDGNIVAIFGQQK
                     VETTDEGQVFHRFREGLLLPGGVGAGTLYNGQDMVAWLYATDRFKTPAAGDSLAYSYPK
                     QKEAPMAYQSHRERQAAARRKPGQKYRLSYGYTALPNWTWSPIAADSAGTFRSPHMRSA
                     YLYTSYESPRSEIALLETTGGTRTYINGEPHEGDHYDFGYTLIPVRLKAGLNEIVYTPG
                     RFGRVESKLVKPDKPVMFTKRDLTLPDLIAGEDDPKWAAIRVVNATEKPLEGLSIRTTL
                     ILPDGNRAAKSVEYKTDDILPMAVRKVKFRVPGTDRPELKGNVSARLELLRNRKVIDTV
                     TIALRQVAPDVHHERTFVSRIDGSVQYYSVAPALRTEPADTGAKAFILTVHGASVEARN
                     QARAYKQKEWVNIVAPTNRRPYGFNWEEWGRIDALEVLEEAQRIFPTDTARIYLTGHSM
                     GGHGTWFLGTTYPDKFAAIAPCAGYPDIAGYGSGRGDAMHRRHPLFEPFERGAAAGRVQ
                     ALARNLKQSGVYIHHGSADNVVPPEQAHIMRETLGRFHTDFCYHEFPGGEHWFGDASVD
                     WPPIFEFFARHSIPAESRVDEIDFYTASPAISAQDYWLTVEQQESPYRYTNVKVQREGD
                     TTIRVVVAENAALLTFDLPALKMKAAETVIAFGDGQRLTVPTSRKAIVAYRDGKWKVLD
                     KIDPKEKNARRYGGFKQAFDNRMVFVYSTAGTPAENAWWQAKARFDAETFYYRGNGSVD
                     IVPDKAYDMKKYAGRNVVLYGNADNNRAWAQLLKDCPVQVRDGEVSMGGRSYRGDDLGA
                     YFVYPHPEFPDVLVGVVTGTGEAGMRATSPNNYISGITGFPDLMIFRADMLKDGLDAVE
                     TAGFFDNDWSLKKQDFVTR"
     CDS             complement(3306..3659)
                     /locus_tag="ctg2_1206"
                     /transl_table=11
                     /translation="METFLTVILFIFAGFWLLGIIGRWMLRWWIAKKQREFQQQFGGDG
                     TASGGAFGNGAFRGFYTHFGGAGTAAGRKKKKEGEVTVTRAERRSEYQVGKGVGEYVEY
                     EEVETSVLSDGKE"
     CDS             complement(3754..3918)
                     /locus_tag="ctg2_1207"
                     /transl_table=11
                     /translation="MDSYKCDVCDWVYNPEEGYPEGGIAPGTPFEDLPDDFECPLCGVG
                     KDMFSKIEK"
     CDS             complement(3959..5311)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_1208"
                     /sec_met_domain="Lyase_1 (E-value: 1.7e-50, bitscore:
                     169.2, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNRLTAISPVDGRYRGKVEQLGEYFSEYALIRYRVQVEIEYFI
                     ALCEEPLPQLAAFDKKRYGALRGIYKDFSIADAQRVKEIEQTTNHDVKAVEYFIKEKMD
                     AIGLGDEREFVHFGLTSQDINNTATPYSLKAATEAIYYPALDELLGKLEELAEAWSSVP
                     MLAHTHGQPASPTVLGKEIRVFVERLGKQLAQLKAIPFPAKFGGATGNFNAHSVAYPDI
                     DWVAFANRFVNGTLGLDRSQFTTQIEHYDNLAALFDAFKRINTILVDLSRDMWTYISME
                     YFKQKIKAGEVGSSAMPHKVNPIDFENAEGNLGMANAIFEHLAAKLPVSRLQRDLTDST
                     VLRNIGVPVAHTLIAVSSLMKGLGKLIINREAIDRDLDDNWAVVAEGIQTILRREKYPN
                     PYEALKALTRTNKGITQADIAAFIDGLDVPEPVKQELRALTPHTYIGIFAE"
     CDS             complement(5685..6947)
                     /locus_tag="ctg2_1209"
                     /transl_table=11
                     /translation="MADNNNKGQTHEHCSFCGAPATQVGMIIHGQEANICDNCAERAWE
                     IVQQEMESRAKNEAVQTIGEAMSLYTPQSIKAFLDQYVIGQDRAKKYIAVAVYNHYKRL
                     MHGMANPGDQEDAEIELDKSNILLVGETGTGKTLIARTIARLLNVPFAIVDATALTEAG
                     YVGEDVESILSRLLQAADYDVAAAERGIVFIDEIDKIARKSDNPSITRDVSGEGVQQAL
                     LKILEGTVVNVPPQGGRKHPDQKYIQVNTRNILFVAGGAFDGVQKKIAQRLNTRVVGYG
                     QQQKIAEVDRDNLLQYITPKDLRSFGLIPELIGRLPVLTYLEPLGREALRRILTEPKNA
                     IVKQYVRLFELDGVKLTFDADVLDYIVDKAIEYKLGARGLRSICEAIMMDAMFEVPATK
                     RKTFRVKLDYARSRVENMHVA"
     CDS             complement(6961..7641)
                     /locus_tag="ctg2_1210"
                     /transl_table=11
                     /translation="MDPIKEFERYARLGRGISSLAMHRYDRIAAEYISPTIIEERQLNV
                     ATMDVFSRLMMDRIIFLGVPIYDDAANIIQAQMLFLESTDPKSDIQVYLNTPGGSVSAG
                     LGIYDTMQLIAPDVATICTGMAASMGAILLTAGTKGKRSALQHSRIMIHQPLGGVEGQA
                     SDIEITARQILKTKEELYSILADHSGVDIKKIEQDADRDFWMTSAEAAEYGLIDGVLTK
                     REEI"
     CDS             complement(7930..9246)
                     /locus_tag="ctg2_1211"
                     /transl_table=11
                     /translation="MNVVRENLENQTALLRIAVGEADYKEQVDKQLKDYKRKANVPGFR
                     PGMVPMGIINKMYRKSVVADSAYRKATDAAFDYIKENGIETVGDLMPSEKQGELDFDNG
                     TDFEFVFEIGLAPEVELALTKKNSLTKYVIEPNDDMRKGFRSNYMRRFGKLADVDVVAD
                     DEALTGTLTQGETTVEDAYVGLISMDEEARKPFIGKKVGDTIEVDVNEIYKTPSQRASI
                     LGVKEAELEGMDPKYTFTITQIRKFAEPEMNEEFFKLAFPAGDVTTPEQFDAKIDEQVR
                     GELAKETEFKFTADMRKYLLEKTNLSLPEEFLKNWLYRVNEGKFSMEEIEKEFPQFLDM
                     LRWDLIRRKVMKANNLEITQDDVKAEAKEVAMMQFQYYGMHTVADDMLENFVNSILGNK
                     EEVRKIYDKVGERKVIDAVAAQIKVNEKTVSPEEFQKLA"
     CDS             9330..9893
                     /locus_tag="ctg2_1212"
                     /transl_table=11
                     /translation="MTLIYDKAFRRLSGADGLPDGDFEKCTFLECDFTGADFSDADFAD
                     CAFERCRLVMSKFEQAGMRDVLFSGCEVRGVDFGLCRKFGFSTAFRRCHLSFCSFHELK
                     MPKTVFEGCELIECFFSECDLTRADFSACDLERTLFERCKLEKADFRTAFRYAIDPAAN
                     RMRGARFSREGLEGLLVQYGLEIE"
     CDS             complement(10001..11164)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1213"
                     /sec_met_domain="OAD_beta (E-value: 1.1e-152, bitscore:
                     505.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENHSFFEFIGANLQQFLSYTGFANVTPGHLIMICFGLAFIYLAI
                     AKKYEPMLLLPIGFGILVGNIPFVPGLQIGVYEDGSVMNYLYFGVLKGVYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQLGIFGAYIAALALGFTAAEAGAIGIIGGADGPTAIFL
                     SSKLAPDLMGAIAIAAYSYMALVPVIQPPIMKLLTTKKERVIRMKPPRQVSQREKVLFP
                     IIGMLLTCFLVPSGLPLLGMLFFGNLLKESGVTKRLANTASGPLIDIVTILIGLTVGAS
                     TQATTFLTWKSLGIFGLGAASFVVATFGGVLFVKFFNLFLKEGNKINPLIGNAGVSAVP
                     DSARVSQEVGIKYDKTNYLLMHAMGPNVAGVIGSAVAAGILLGFLGS"
     CDS             complement(11171..11623)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 71.8; E-value:
                     1.1e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1214"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.7e-21, bitscore:
                     71.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKIKINGNEYAVSVSNVEDNTALVNVNGTQYEVEVEGMTAPK
                     VTKTPKIVQQPAVADTDPHPATARTASPASTASVAAGNIKSPLPGVVLDVMVHVGDAVK
                     TGQRLMILEAMKMENNIDSDRDGTVKEIKARKGDSVLEGDILITIG"
     CDS             complement(12189..13097)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1215"
                     /sec_met_domain="OAD_gamma (E-value: 4.3e-11, bitscore:
                     40.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKRLLLILCLAVSAGGVLRAQGLKDIRINEVLVDNRTSYVDDHG
                     NHVGWIELYNTGYSSVNIGGAYLTVKQGDATRTYRIPKNDARTLIAPQGYVIFFADSTS
                     NRGTFHTNFVLDETGYLAFMDQGKNVVDSILYDVAAQQPDVSIGWTDDPETGEETFGPL
                     AGITPMQANEIEEKMLASEKFRQRDPSGAVMAITAMSVVFSALILLYLSFKFIGKSMIR
                     ASLKKEQKAVSAMPEAVKTAVKPEPGLIGEEIAAIAVALRRYEEDLHDIESHVLTINRV
                     ARAYSPWSSKIYGIDNQPNRK"
     CDS             complement(13112..14674)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1216"
                     /sec_met_domain="CT_Btheta (E-value: 2.6e-291, bitscore:
                     963.2, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVNQEKIKELVALREKAKLGGGQKRIDSQHAKGKLTARERIDLL
                     LDEGSFEEFDMFVTHRCTNFGIEKESYYGDGVVTGYGTIDGRLVYVFSQDFTVFGGSLS
                     ETFAAKICKVMDMAMKNGAPVIGINDSGGARIQEAVNALSGYTEIFQRNIMASGVIPQI
                     SAIFGPCAGGAVYSPALTDFILMNKGTSYMFVTGPKVVKTVTGEEVTQEQLGGASMHST
                     KSGVAHFVSETEEEGMAMIRKLLSYLPQNNLEDAPLAVCTDDIDRIEDALNEIIPDNPN
                     KPYDVLDVIHAIVDNREFLESQRTFAPNIVTGFARFNGQSVGIIANQPKYYAGVLDINA
                     SRKAARFVRFCDAFNIPIVTLVDVPGFLPGTAQEYGGIITHGAKLLFAYGEATVPKVTV
                     ILRKAYGGAYCVMSSKHLRGDLNYAWPTAEIAVMGAQGAVEVLMAKEAKAIGDDAERAK
                     FLAEKEEEYRTKFANPYVAAKYGYIDDVIEPRNTRFRIIRALQSLVTKKVVNPPKKHSN
                     IPL"
     CDS             complement(15037..15453)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1217"
                     /sec_met_domain="Glyoxalase_4 (E-value: 4.9e-24, bitscore:
                     81.8, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNISHIEHLGIAVKSLEQAIPYYEKVLGLKCYSIEEVADQKVRTA
                     FFKVGQTKIELLEPTSEESTIAKFIEKRGEGIHHLAFAVADGVAEALAECEGKGVQLID
                     KAPRKGAEGLNIAFLHPKSTQGVLTELCEDPAKK"
     CDS             complement(15550..15915)
                     /locus_tag="ctg2_1218"
                     /transl_table=11
                     /translation="MIRKFFFAALFASAWDLLPAQTLSVTPSVIQMGEIAFKSKNRVEL
                     TCVNRSDKPLVIRDIRTDCTCTKPSWPKSPLMPGDSVRVAVTLTPTDRGAFYKTIRFVT
                     VPASDPAPQAVLRGKVY"
     CDS             16138..17352
                     /locus_tag="ctg2_1219"
                     /transl_table=11
                     /translation="MKKISLIASLAAGALLFSCSDPYKGLDPKLAADLQANIAAAGENG
                     QELLAALEQAPENQKEGMAYLIAYMPEGDRDTLKAGFLLEEVGWAYKARETFPWTRTLP
                     DSVFYNDVLPYASMNEHREPWRAMFWEKLYPLVDSITDVRAAIDTINKQLQYLVKVEYN
                     TKRKKPHQSPGESMEIGMASCSGLSILLTDAFRTMGIPSRIAGTPLWVSKEGNHNWTEV
                     WIDGQWYFTEYYPTPALNHSWFLERAGKADKSDPIYWMYATSWKPTGLHFPMVWDKDNE
                     NVPGIDVTDFYIDLYNAQMAEAKNGAPVVIRVFKAEDGGRSSADRVAQDVKVVDADGNM
                     VAAGKTAGPTADMNDYLTLYLPFGKELKAEFTDAAGTVHSAPVSTPKARKGEQPAPIEI
                     ELYLE"
     CDS             complement(17950..19044)
                     /locus_tag="ctg2_1220"
                     /transl_table=11
                     /translation="MAKTKTARRKASAKGKRRKLSARGITIIAALALVFLTIAVAIGWK
                     QYDYRFGTAIVREGTVQVRTGTSFDELSRMLADSGYLKTPRKWDSYARSNGLDSVRAGN
                     YTLREGMAYRTALTRFFYGRETPVRLTFNNIRTMDRLAGVVSRYIEADSAAILRTLNDE
                     SVIGETGLTKATFPSLFIPNTYEVYWTMTPREFVTRMQKEHDRFWNEERRAKAEKLNLT
                     PEQISTIASIVIEETKFSGEMTQVAGVYINRLRAGIPLQADPTVKFALGDPSIRRVLNR
                     HLAYDSPYNTYRYAGLPPGPICVPPVSALDATLAYAEEDRKHDYYYFCAKADFSGRHAF
                     ARTLPEHNRNAAAYAKELNRRGIR"
     CDS             19309..19923
                     /locus_tag="ctg2_1221"
                     /transl_table=11
                     /translation="MIIKLYPENPNERTVRQVADILRRGGVIVYPTDTVYALGCALDQP
                     KAIERLRTIRGGKDSAEMSIVCAEIGEAAEYAKVDNLVFKLLKHNLPGPFTFILPASSR
                     ISDKVMIGRKTVGVRIPDNSIALAIVRELGMPLVTTSVRTDDVGDEVEYITDPELISER
                     YPAVDAVIDGGIGDNFASTVVDCTVSGEVDVVRQGRRELEF"
     CDS             19930..20493
                     /locus_tag="ctg2_1222"
                     /transl_table=11
                     /translation="MDEQTRKQKYRGELLTAGMVLGLVMFAVVVLQYLFRDAGGFVVGL
                     LSFANFAAIVAVLIVYGRRAAALCPPDPVLRPNGFTYGRAFGFSILVSLLSGIVYGVGY
                     FLLTEVIDPRYFGRAMERVAELYISSGLMTAEQVQAGMALMHNLFVVIFANMVAMLFQG
                     GFLSLFTAAIVRYRRPHSSFPPLQ"
     CDS             20504..21451
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_1223"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.7e-32,
                     bitscore: 107.9, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDISLVIPVYNEEESLAPLMEWIARVMGDHGFSYEVIFVDDGSTD
                     ASWEVITRLKGQYPAIRGIRFRRNYGKSPALYCGFDAAQGEVVVTMDADLQDSPDEIPE
                     LYRMVTEEGYDLVSGWKQKRYDPLGKTLPSKFFNMTARVTSGIRLHDFNCGLKAYKKKV
                     VKSIEVYGEMHRFIPILAKQAGFRRIGEKVVQHRARQFGVSKFGWERMIKGYIDLLTVL
                     FMTRFGRRPMYIFGGIGTLMFLVGAVITVYLISEKLYLQHHGLPLRPVTDQPLFYIALL
                     AVGLGVQTFLAGFLGEMVNRSAPERNRYLVDERL"
     CDS             21680..22684
                     /locus_tag="ctg2_1224"
                     /transl_table=11
                     /translation="MSKIKVGINGFGRIGRLVFRAALTKSDIEIVGINDLVPVDYMAYM
                     LKYDTMHGQFKGTIEVKDGKLVVNGQAIRVTAEKDPANLKWDEVGAEYVVESTGLFLTK
                     ELAEKHIQAGAKRVVMSAPSKDDTPMFVMGVNNKEYKGQTIVSNASCTTNCLAPIAKVL
                     NDKFGMVDGLMTTVHSTTATQKTVDGPSMKDWRGGRAAAGNIIPSSTGAAKAVGKVIPA
                     LNGKLTGMSLRVPTLDVSVVDLTCNLAKDVTYDEICQAMKEASEGELKGILGYTEDAVV
                     SSDFLGDARTSIFDAKAGIQLTPRFVKVVSWYDNEWGYSNKVVELIQHMNTVK"
     CDS             complement(23195..23677)
                     /locus_tag="ctg2_1225"
                     /transl_table=11
                     /translation="METIRIGNGYDVHALAEGLPMWLGGIRIEHNKGFVAHSDGDVLIH
                     ALCDALLGALALGDIGLHFPDNAQEFKDIDSKILLRRCIALVQEKGYRLGNADCTILAQ
                     APKLRPYIDRMRKTLAPLLGSAVEDISIKATTTERLGFTGREEGVAVYATVLLYHK"
ORIGIN
        1 tcgacggaca ggtgcgtgaa ttatacgaca agtataaaga caaggggctg gaggtgatag
       61 gactgaccga atccgtcgcc acgatccgcc aagtgtacga gggactgccg aaagacgaaa
      121 agacgccgtc ggccggcgtc gaagacatgc gtcccgtatt ggccggcatg ctggaacatc
      181 cctggaccga agtcgaggtc gagaccgacc atccggacaa ccgatcgttg atggacgcct
      241 ataaattcag cggttggccg tttttcgtgc tgatcggccc ggatgggaag atcgaggccc
      301 gcggctttac cgacgccttt ttcaaggccc ggaccctgct cgacgagaag ttgggcgctc
      361 cggccgagta aacggacgga acggtcaagg cctgacctga ccgggaaggg ccggggaaac
      421 ggccgacgaa taaccgaggg gcggtaaagc acgatgcttt accgcccctc ggttcaaaaa
      481 cggtcggcgc ccgatcttat tagcgggtga cgaaatcctg ttttttcagc gaccagtcat
      541 tgtcgaagaa tccggccgtt tcgacggcat ccaggccgtc tttcaacatg tcggcccgga
      601 agatcatgag gtccggaaaa cccgtgatgc ccgaaatgta gttgttcgga ctggtagccc
      661 gcatcccggc ctcgccggta ccggtcacga cgccgacaag gacatccggg aactccggat
      721 gcggatagac gaaataagct ccgaggtcgt ccccccgata ggaacggccg cccatcgaaa
      781 cttcgccgtc ccgcacctgt accggacaat ctttcaacaa ctgcgcccag gctcggttat
      841 tgtccgcatt gccgtacagg actacattgc ggccggcgta tttcttcata tcgtacgcct
      901 tgtccgggac gatgtccacc gacccgttgc cccgatagta gaacgtctcc gcatcgaaac
      961 gcgccttggc ctgccaccag gcattctctg ccggagttcc ggcagtcgaa tagacgaaca
     1021 ccatccggtt gtcgaaagcc tgtttgaatc cgccgtaacg ccgggcgttt ttctctttcg
     1081 ggtcgatctt gtccagcact ttccattttc cgtcgcggta agcgacgatc gctttgcgcg
     1141 aggtcggaac cgtgagccgc tgcccgtcgc cgaacgcgat aaccgtttcg gcggccttca
     1201 tcttcagcgc aggcaggtcg aaagtcagca acgccgcatt ttcggccacg actacgcgga
     1261 tcgtggtgtc gccttcgcgc tgcaccttta cattcgtgta gcggtaggga ctttcctgtt
     1321 gttccacagt cagccagtaa tcctgtgccg agatggcggg cgatgcggtg tagaaatcga
     1381 tttcgtctac ccggctttcc gcagggatcg agtggcgggc gaagaattcg aaaatcgggg
     1441 gccagtccac gctggcgtcg ccgaaccagt gttcgccgcc cggaaattcg tggtaacaga
     1501 agtcggtatg gaaccggccc agcgtttcgc gcatgatgtg ggcctgttcg ggcggtacca
     1561 cattgtcggc cgatccgtga tggatatata cgcccgactg cttcaggttg cgggccagcg
     1621 cctgtacgcg gcctgccgcc gcgccccgtt cgaagggttc gaagagcgga tgacggcggt
     1681 gcatggcgtc ccccctgccg ctgccgtagc ccgcgatgtc cggataaccg gcgcaggggg
     1741 cgatggcggc gaatttgtcg ggataggtcg taccgaggaa ccaggtgccg tggccgccca
     1801 tcgaatggcc ggtcaggtag atgcgtgcgg tgtcggtggg gaagatgcgt tgtgcctctt
     1861 ccagcacctc cagggcgtcg atgcggcccc actcttccca gttgaaaccg tagggccggc
     1921 ggttggtcgg agcgacgata ttgacccatt ccttttgttt ataggcgcgg gcttggttgc
     1981 gggcttcgac ggaggcgccg tgcacggtca ggatgaacgc cttggcaccc gtgtccgccg
     2041 gttccgtccg cagggccggg gccacgctgt aatattgcac gctgccgtcg atgcggctca
     2101 cgaaagtgcg ctcgtggtgt acgtccgggg ctacctgccg cagggcgatg gtcacggtgt
     2161 cgatgacttt acggttccgg agcagttcca gccgggccga tacgttgcct ttcagttcgg
     2221 ggcggtcggt gccgggaacc cggaatttga ctttccgaac ggccatcggc aggatatcgt
     2281 cggtcttgta ttccacgctt ttcgcggccc ggttgccgtc cggcaggatg agggtcgtgc
     2341 ggatgctcag cccttcgagg ggtttctcgg tagcgttcac cacgcggatc gcggcccatt
     2401 tcggatcgtc ctccccggcg atcaggtcgg gcagggtcag gtcgcgtttg gtgaacatca
     2461 ccggtttgtc gggtttgacc agtttcgatt ccacgcgtcc gaaccggccg ggggtgtaga
     2521 cgatttcgtt cagtcccgct ttcaaccgca cggggatcag ggtataaccg aagtcgtaat
     2581 gatcgccttc atggggttcg ccgttgatgt aggtgcgcgt tccgccggtg gtctccaaca
     2641 aggcgatttc ggaacggggc gattcgtagg aggtgtagag gtaggccgaa cgcatgtgcg
     2701 gactgcggaa tgtgccggcg gagtcggctg cgatcgggct ccatgtccag ttgggcagtg
     2761 ccgtgtaacc gtagctgagc cggtatttct gcccgggttt gcgccgggcc gcggcctgtc
     2821 tctcccggtg cgactgatag gccatgggag cttctttctg tttcgggtag gagtatgcga
     2881 ggctgtcgcc tgctgcgggg gtcttgaaac ggtcggtggc atagagccag gcgaccatgt
     2941 cctggccgtt gtagagggta ccggcgccga cgccgccggg caggagcaat ccttcgcgga
     3001 aacggtggaa aacctgccct tcgtcggtgg tttccacttt ttgttgtccg aagatggcga
     3061 cgatattgcc gtcgccttcg gaggtctgcc gggcgtgcag ggtctgcccg ccgacggcga
     3121 gtgcggcgca taacgccgtg ccgcgcaagg tcttgaggaa gaatggagtc atgccgttgt
     3181 tctctgtggt tattaatgga aaccgtaaaa ataacgattt tcacggaaaa accgcattcc
     3241 ggagtaccgg aatgcggttt cagactgtcg ttcgtgcggg acgaagcgcg tgtgccgcct
     3301 gtcggtcatt ctttgccgtc ggacaggacg gaggtttcga cctcttcgta ttcgacgtat
     3361 tcgccgacgc ctttgccgac ctggtattcg ctgcgccgtt cggcgcgggt gacggtcact
     3421 tcgccctctt ttttcttttt ccgtccggcg gcggttccgg cgcctccgaa atgggtgtag
     3481 aagccgcgga acgctccgtt gccgaaagcg cctccggagg ccgtgccgtc gccgccgaat
     3541 tgttgctgga attcgcgctg tttcttggcg atccaccacc gcagcatcca ccgcccgatt
     3601 attccgagca gccagaatcc ggcgaatatg aacagtatga cggtcaggaa agtctccatc
     3661 tggacgggtt acttgattgt cttgcaaaga taacgcaaag gagcgtattt ttagtacgct
     3721 ccttcgaacc ggcggatgtc cggaaccgga cctttatttt tcgattttgc tgaacatgtc
     3781 tttgcccacg ccgcagagcg ggcattcgaa atcgtccggc aggtcttcga acggtgtccc
     3841 cggggcgatg ccgccttcgg ggtatccttc ttcggggtta taaacccagt cgcatacgtc
     3901 gcatttgtag ctgtccatgg tagtaatgaa tttagttgtt ggttgatcgt tctgtctctt
     3961 attcggcaaa tatgccgatg taggtatgag gggtcagcgc gcgcagctcc tgtttcacgg
     4021 gttcgggcac gtccagaccg tcgatgaaag ccgcgatgtc ggcctgcgtg atccctttgt
     4081 tggtgcgggt cagggctttc agcgcttcgt aggggttcgg gtatttttcg cgccgcagga
     4141 tggtctgtat cccttcggcc acgacggccc agttgtcgtc cagatcgcgg tcgatggctt
     4201 cccggttgat aatcagtttg ccgaggcctt tcatcagcga gctgacggcg atcagggtgt
     4261 gcgccacggg tacgccgatg ttccgcagta cggtggagtc ggtcaggtcg cgttgcagac
     4321 gggataccgg caattttgct gccaaatgtt cgaaaatggc gttggccatt cccagattcc
     4381 cttcggcgtt ttcgaaatcg atcggattga ctttatgcgg catggccgag gagcctactt
     4441 ctccggcttt gattttctgc ttgaaatatt ccatcgagat gtaggtccac atgtcgcgcg
     4501 agagatcgac gaggatggtg ttgatgcgtt tgaaggcgtc gaacagggcg gcgaggttgt
     4561 cgtagtgttc gatctgggtg gtgaactgcg agcggtcgag gcccagggtc ccgtttacga
     4621 accggttggc gaaagcgacc cagtcgatgt cggggtaggc gacggagtgg gcgttgaagt
     4681 tgccggtcgc tcctccgaat ttggcgggga aggggatggc tttcagctgg gcgagctgtt
     4741 tgccgagccg ttcgacgaag acgcggatct ctttgccgag cacggtaggc gaggcgggct
     4801 gtccgtgggt gtgggccagc atgggcacgg aactccacgc ttcggcgagt tcttccagtt
     4861 tccccagcag ttcgtccagg gcggggtagt agatcgcttc ggtcgcggct ttgaggctgt
     4921 atggcgtggc ggtgttgttg atgtcctgcg aggtgaggcc gaaatgtacg aattcgcgtt
     4981 cgtcgccgag tccgatggcg tccatcttct ctttgatgaa gtattcgacg gctttcacgt
     5041 cgtggttggt ggtctgctcg atctctttga cgcgctgggc gtcggcgatg ctgaagtctt
     5101 tgtagatgcc gcgcagggcg ccgtagcgtt tcttatcgaa tgcggcgagc tgaggcagag
     5161 gctcttcgca cagggcgatg aagtattcga tctcgacttg cacgcggtaa cggatcaggg
     5221 cgtattcgga aaaatattcg cctaactgct ccactttgcc gcggtaacga ccgtcgacgg
     5281 gcgaaatggc tgtcaatcga ttcaattcca taaaatgtct atttaaggtt cgtttattcg
     5341 gtacattagg tttgaggtga ctgttctctt tgtgaacaaa gagaaccaga aaaacttttt
     5401 gagatgcttc gcatctcctg agcctggcgg atgacctttc ctttgaaaac ttgttctgta
     5461 acggataggg ggctatcaat gtcgttaccc gatgccctct atccgttaca gaacaaagaa
     5521 gttcgcaaga aaaggcttct ggcaaactga gggggcgcaa acctgctcga aagtttggct
     5581 tcgccttcct cctggcgcct cggctctttg gttctttctt ttcaaagaaa gaacagtgga
     5641 ctctaccctc tacgtacaaa taaacgaacg attaatattt acgtttatgc gacgtgcatg
     5701 ttttcgacgc gggagcgggc atagtccagt ttgactcgga acgttttgcg tttggtcgcc
     5761 ggcacctcga acatcgcgtc catcatgatc gcctcgcaga tcgagcgcag tccccgcgcc
     5821 cccagtttgt attcgatcgc cttgtccacg atatagtcca gcacatccgc atcgaacgtc
     5881 agttttacgc cgtccagttc gaacagccgg acatactgct tcacgatcgc gtttttaggt
     5941 tccgtcagga tacgtcgcaa cgcctcgcgt cccagcggtt ccaggtaagt caataccggg
     6001 aggcggccga tcagttccgg aatcagcccg aagctgcgca aatctttcgg cgtgatgtac
     6061 tgcaacagat tgtcccggtc tacctccgct atcttctgct gttggccgta gcccaccacg
     6121 cgcgtgttca gccgttgcgc gatcttcttc tgcaccccgt cgaacgctcc tcccgccacg
     6181 aacaggatat tccgggtatt cacctgtatg tacttctgat ccggatgttt acgcccgccc
     6241 tgcggcggca cgttcaccac cgtgccctcc aggattttca gcaacgcctg ctgcacccct
     6301 tcgcccgaca cgtcgcgcgt gatggacggg ttgtcgctct tgcgggcgat cttgtcgatc
     6361 tcgtcgatga agacgatgcc ccgttcggcc gcggccacat cgtaatccgc cgcctgcagg
     6421 agccgcgaca ggatgctttc gacatcctcc ccgacgtagc ccgcctcggt cagcgccgtg
     6481 gcgtccacga tggcgaacgg cacgttcagc agacgagcga tcgtccgggc gatcagcgtt
     6541 ttgcccgttc ccgtttcgcc gaccagcagg atgttcgatt tgtccagctc gatctccgca
     6601 tcctcctggt cgcccggatt cgccatgccg tgcatcagcc gtttgtaatg gttgtaaacg
     6661 gctaccgcga tgtatttttt agcccggtcc tgcccgatga cgtattggtc gaggaacgct
     6721 ttgatagact gcggcgtata gagcgacatc gcttcgccga tcgtctgtac cgcttcgttt
     6781 ttggcccggc tttccatctc ctgctgtacg atctcccacg cccgttcggc gcagttgtcg
     6841 cagatgttgg cctcctgtcc gtggataatc attccgacct gcgtggccgg ggcaccgcag
     6901 aacgaacagt gttcgtgcgt ctgtccttta ttgttgttgt ctgccatggc gcaatttcgc
     6961 ttagatctcc tcccgtttgg tcagcacccc gtcgatcagg ccgtattcgg ccgcttcggc
     7021 cgaagtcatc cagaagtccc ggtcggcgtc ctgttcgatt tttttgatgt ccacgccgct
     7081 gtggtcggcc aggatggagt agagttcctc tttggttttc agtatctggc gcgcggtgat
     7141 ttcgatgtcg ctggcctggc cttcgacccc gccgagcggc tggtgaatca tgatgcgcga
     7201 atgttgcagg gccgagcgtt tgcctttggt gcccgccgtc agcaggatgg cccccatcga
     7261 ggcggccatg ccggtgcaga tggtcgccac gtcgggcgcg atgagctgca tggtgtcgta
     7321 gatgcccagt ccggccgata ccgatccgcc cggagtgttg agatagacct gtatgtcgct
     7381 tttggggtcg gtcgattcga ggaaaagcat ctgggcctgg atgatgttgg cggcgtcgtc
     7441 gtagatcggc acgccgagga agatgatgcg gtccatcatc aggcgggaga atacgtccat
     7501 cgtggcgacg ttcagctgcc gctcttcgat gatggtcggc gagatatatt cggccgcgat
     7561 gcggtcgtaa cggtgcatgg ccagcgagga gattccgcgt ccgagccgcg cgtaccgttc
     7621 aaactctttt ataggatcca ttcgtcggtg taaaatgttg caagaagtaa aattacgact
     7681 tttttacaaa ataaggcgca tcttgttgtc aaaatgcgcc ttgcgggttg aatataattg
     7741 cactaaagac tcggagcgcc gggagcatct tgtttacgac gctcatgcgt cgcgaacgat
     7801 tttcctgttc cggcgggggt agcgcgaacc ggcggatgtt gcactcccgc acaggtcggg
     7861 aaagcctgga gggagcgcta tttcgtgccg tccggaatac ctcgtccaat gctaatgccg
     7921 gaacgggtac tacgccagtt tctggaactc ttccgggctg acggtctttt cgttcacttt
     7981 gatttgcgcg gctacggcgt cgatcacttt gcgttcgccc accttgtcgt aaatcttgcg
     8041 tacctcttcc ttattgccga ggatcgagtt cacgaagttt tcgagcatgt cgtcggctac
     8101 ggtatgcatc ccgtagtact ggaactgcat catggccacc tctttggctt cggctttcac
     8161 gtcgtcctgt gtgatttcga ggttgttcgc tttcatcacc ttgcggcgga tcaggtccca
     8221 acggagcata tcgaggaact gcgggaattc cttttcgatc tcttccatcg agaatttgcc
     8281 ttcgttcacg cggtagagcc agtttttcag gaactcttcc ggcagggaga ggttcgtttt
     8341 ttccagcagg tatttccgca tgtcggcggt gaacttgaat tcggtctctt tggccagttc
     8401 gccgcgtacc tgttcgtcga ttttggcgtc gaactgttcc ggggtggtca cgtcgccggc
     8461 cgggaaagcc agtttgaaga actcttcgtt catttccggc tccgcgaatt tacggatctg
     8521 ggtgatggta aaggtgtatt tcggatccat cccttcgagt tcggcctctt tcacgccgag
     8581 gatcgaagcc cgctgggagg gggttttgta gatttcgttc acatcgactt cgatcgtgtc
     8641 gccgactttc ttgccgatga acggcttgcg ggcctcttcg tccatgctga taagccctac
     8701 gtaggcgtct tcgacggtgg tctcgccctg ggttagggtg ccggtcagcg cttcgtcgtc
     8761 ggccacgacg tccacgtccg ccagtttgcc gaaacgccgc atgtagttgc tgcggaaacc
     8821 tttgcgcata tcgtcgttcg gttcgatgac gtatttggtg aggctgttct ttttggtcag
     8881 cgccagctcc acttcgggag ccagcccgat ttcgaatacg aattcgaagt cggtgccgtt
     8941 atcgaaatcc agttcgccct gtttttccga cggcatcagg tcgcccacgg tttcgattcc
     9001 gttttccttg atataatcga acgcggcatc ggtggctttg cggtaggcgc tgtcggccac
     9061 tacgcttttg cggtacatct tgttgatgat acccatcggc accatgcccg gacggaagcc
     9121 cggcacgttg gctttgcgtt tataatcctt gagttgtttg tccacctgtt ccttgtaatc
     9181 ggcctcgccc acggcgatcc ggagcagggc ggtctggttt tcgagatttt ctctgactac
     9241 gttcattgag agtatcttgt tagttttatt tgctttaagg agaggcaaag gtaacggatt
     9301 tttacgaaaa tccgctactt ttggcactga tgaccctgat ttacgacaag gcgttccgcc
     9361 gattgtccgg tgcagacggg ctgccggacg gggatttcga aaagtgcacg ttcctggaat
     9421 gcgattttac gggggcggac ttttcggatg ccgattttgc ggattgtgcg ttcgaacggt
     9481 gccgtctggt catgtcgaag ttcgaacagg ctggcatgcg ggatgtactc ttctcggggt
     9541 gcgaggtgcg gggcgtcgat ttcggtcttt gccgcaaatt cggtttctcc acggcgttcc
     9601 gtcgttgcca cctcagtttt tgctcgttcc atgagctgaa aatgccgaag acggtgttcg
     9661 aggggtgtga gctgatcgag tgttttttct cggaatgcga cttgacgcgg gcggattttt
     9721 cggcgtgcga tctggaacgg acgctgttcg agcggtgtaa gctggagaag gcggatttcc
     9781 gcacggcgtt ccggtatgcc atcgaccctg cggccaaccg gatgcggggc gcccggtttt
     9841 cgcgcgaggg gctggagggg ttgctcgtac agtatggatt ggagatcgaa tagggatggt
     9901 ccggtatcgt gtgccatacc ggcggcaaaa cgggaaatcc ataaaagacg cccccgcggc
     9961 catcaatggc cgcgggggcg tcttttatcg gggaacggca tcaggagccg aggaagccga
    10021 gcaggatacc ggccgctact gccgaaccga tcaccccggc gacgttcggt cccatcgcgt
    10081 gcatcaacag gtagttggtc ttgtcgtatt tgatgccgac ttcctgcgaa acgcgggccg
    10141 agtcgggcac ggccgagacg ccggcgttcc cgatcagcgg gttgatctta ttgccctctt
    10201 tgaggaacag gttgaagaat ttgacgaaca gcacgccgcc gaaagtggcc accacgaacg
    10261 aggcggcgcc caggccgaag atgccgagcg atttccaggt caggaaggtg gtcgcctgcg
    10321 tggaagcgcc cacggtcagg ccgatcagga tcgtcacgat gtcgatcagc ggcccgctcg
    10381 cggtgttggc caaccgtttg gtcactccgc tctctttcag aaggttaccg aagaagagca
    10441 tccccagcag gggcaggccg gagggtacga ggaaacaggt cagcagcatc ccgatgatgg
    10501 ggaagagcac tttctcgcgc tgcgacacct ggcgcggcgg tttcatgcgg atcacccgct
    10561 cttttttcgt ggtgagcagc ttcatgatcg gcggctggat caccggtacc agcgccatat
    10621 aggagtaggc cgcgatggcg atggctccca tcaggtcggg cgcgagtttc gagctgagga
    10681 agatggctgt cgggccgtcg gccccgccga taatcccgat ggccccggct tcggcggccg
    10741 taaagcccag cgcgagcgcg gcgatatagg ctccgaagat gcctaactgc gcggctgccc
    10801 cgatcagcat cagtttcggg ttggaaatca gggccgaaaa gtcggtcatc gctccgattc
    10861 cgaggaaaat cagcggggga tagacgcctt tgagcacgcc gaaatagagg tagttcatga
    10921 cggaaccgtc ttcgtaaacc ccgatctgga ggccgggtac gaacggaatg tttcccacca
    10981 gaataccgaa accgatgggc agcaggagca tcggttcgta tttcttggcg atagccaggt
    11041 agatgaaggc caggccgaag cagatcatga tcagatgccc cggcgtgacg ttcgcaaaac
    11101 cggtatagct caggaactgc tggaggttcg cgccgataaa ttcgaaaaag ctgtggttct
    11161 ccatagtacg ctatccgatt gtgattaata tatcgccttc gagcacggag tcgcctttgc
    11221 gggctttgat ctctttcacg gtgccgtcgc ggtcggagtc gatgttgttc tccattttca
    11281 tcgcttcgag gatcatcagc cgctggccgg tcttcactgc gtcgcctacg tgtaccatta
    11341 cgtcgagcac gacgccgggc agcggcgatt tgatgtttcc tgcggctacc gaggcggtcg
    11401 aagcggggct ggcggtccgg gcggtcgccg gatgcgggtc ggtatcggcc acggcgggtt
    11461 gttgtacgat cttgggggtt ttggtgactt tcggagcggt catcccttcc acttctactt
    11521 cgtattgggt gccgttgacg ttcaccaatg cggtgttgtc ttctacgttc gatacggata
    11581 cggcgtattc gttgccgttg atcttgatct tatactcttt catgtaaatt cttttttaac
    11641 ggtccgttta tccatactct tgggtagagt ccactgttct ttcttttcaa agaaagaacc
    11701 aaagagccga cgcagcagcc gagcgtcatc gaactcgttc ggatggccga ggcgccagga
    11761 ggaaggcgaa gccaaacttt cgagcaggtt tgcgattcct cgtttatcgg aaaccttttt
    11821 cttgcagact tctttgttct gtaacggata ggggcatcag gtatacgctg ttatagcccc
    11881 tatccgttac agaacaagct catttctaaa gaataggtta tccgccaggc tcaggaggtg
    11941 cgaagcatct caaaaagttt ttctggttct cgctaactgc gctgcgcttg ttttgcctgc
    12001 ggcttcctcg tgctaccttg ccaaagaccg tgaacggtct ttggtctcgg aacgctactc
    12061 ggttcctcct cgccgcttac catagcccgc aagcggtctc cggatgcgct ggcagcgtcg
    12121 gttgttcaca aagagaacag ttcacgctac ccaaacaata tggataaacg aacggtgaaa
    12181 gggacggttt atttgcggtt aggctggttg tcgataccgt agattttgga actccacggc
    12241 gagtaagccc gcgccacacg gttgatggtc aggacgtgcg attcgatgtc gtgcagatct
    12301 tcctcgtaac ggcgcagcgc gacggcgata gccgcaatct cctcgccgat cagtccgggt
    12361 tccggtttga cggccgtttt caccgcctcc ggcatggccg atacggcttt ctgctctttt
    12421 ttgagcgacg cccgtatcat cgacttaccg atgaacttga acgacaggta aagcaggatc
    12481 agcgccgaga acaccacaga catggcagtg atcgccatga ccgcccccga agggtcccgt
    12541 tgccggaact tctccgaagc cagcatcttc tcttcgattt cattggcctg catcggagtg
    12601 atccccgcca gcgggccgaa agtctcctct cccgtttccg gatcgtccgt ccaaccgatc
    12661 gacacgtccg gctgctgggc tgccacatcg taaagaatcg aatccacgac attctttcct
    12721 tggtccataa aggccaggta gcctgtttcg tccagcacga aattggtatg gaacgtcccc
    12781 cggttcgaag tgctgtccgc aaagaaaatc acatagccct gcggcgcgat tagcgtgcgg
    12841 gcgtcgttct tcgggatgcg gtaagtccgc gtcgcgtctc cctgttttac agtcaggtaa
    12901 gccccgccga tgttcacgct cgaatacccc gtgttgtaca gttcgatcca gcccacgtgg
    12961 ttgccgtggt catcgacata gctggtgcgg ttgtccacca gtacctcgtt gatccggata
    13021 tctttcagtc cctgcgcccg cagcacgccg ccggcggata cggcgaggca caggataagc
    13081 aatagtctct tcatcatacg ctcccttcgg tttacaacgg tatgttcgaa tgtttcttcg
    13141 gcggattgac cactttcttg gtcaccagcg actggagcgc ccgaatgatg cgaaaacgcg
    13201 tgttgcgcgg ttcgatcacg tcgtcgatat agccgtattt ggccgccacg taggggttgg
    13261 cgaatttggt gcggtactcc tcttccttct cggccaggaa tttcgcgcgt tctgcgtcgt
    13321 ctccgatcgc tttggcttct ttggccatca gcacttcgac ggctccctgg gcgcccatca
    13381 cggcgatttc cgccgtcggc cacgcatagt tcaggtcgcc ccgcagatgc ttggaactca
    13441 ttacgcaata cgccccgccg taggctttgc gcaggatgac ggtgactttc ggcacggtgg
    13501 cctcgccgta ggcgaagagc agcttggcgc cgtgggtgat gatgccgccg tactcctgag
    13561 ccgtgcccgg caggaatccc ggtacgtcca ccagcgttac gatcgggatg ttgaaagcgt
    13621 cgcagaagcg aacgaagcgt gcggctttgc ggctggcgtt gatgtcgagc acgccggcgt
    13681 agtatttcgg ctggttggcg ataatcccga cgctctggcc gttgaagcgg gcgaagccgg
    13741 tcacgatgtt cggcgcgaag gtgcgctgcg attcgaggaa ctcccggtta tcgacgatgg
    13801 cgtggatcac gtccagcacg tcgtagggct tgttcgggtt gtcggggata atttcgttga
    13861 gggcgtcttc gatgcggtcg atgtcgtcgg tgcagacggc cagcggcgcg tcttcgaggt
    13921 tgttctgggg caggtagctg agcagcttgc ggatcatggc catcccctct tcttcggttt
    13981 cgctgacgaa gtgggccacg cccgatttgg tggagtgcat ggaggcgccg ccgagctgct
    14041 cctgcgtcac ctcttcgccg gtcacggtct tgacgacttt ggggccggtg acgaacatgt
    14101 agctggtacc tttgttcatc aagatgaagt cggtcagggc cggcgagtag acggctccgc
    14161 cggcgcaggg gccgaaaatg gcggatatct gggggatcac cccggaggcc atgatgttgc
    14221 gctggaagat ttcggtatat ccgctcaggg cgttcacggc ttcctggata cgtgcgccgc
    14281 cggagtcgtt gatgccgatc acgggggcgc cgttcttcat ggccatgtcc atcactttgc
    14341 agattttggc ggcgaaggtt tcggacaggg agccgccgaa gacggtgaag tcctggctga
    14401 atacatagac gagccgtccg tcgatggtgc cgtagccggt cacgacgccg tcgccgtaat
    14461 aggactcttt ttcgatgccg aagttggtgc aacggtgggt gacgaacatg tcgaattctt
    14521 cgaagctgcc ttcgtcgagc agcaggtcga tgcgttcgcg ggcggtgagt ttccctttcg
    14581 catgttgcga gtcgatgcgc ttctgaccgc cgccgagctt ggctttctcg cggagcgcga
    14641 caagctcttt gattttttcc tgattgacgc tcataaaaaa gtttgtgtgg ttcggttctt
    14701 attcgtgatt aattcgtttg tttattcgtg cggttgagat tggagagaac tgccgctttt
    14761 tggaaaaagc ggcaccaaaa acttttgtga agctccgctg cgccttaggc tccgcagtcc
    14821 ttttgcattg cgagcttttt attttgtcat tgcagggggc tatttgggta taaatgtgtt
    14881 atatagcccc ctgcaatgac aaaataggaa ctgtcaaaga aaagaggtat ccggcaggcc
    14941 caggagatgc gtcagcatct caaaaagttt tttcggttcc ttttgttcac aaaaggaaca
    15001 gtgccctcaa actcgattgt acgaataaac gaacgattat ttctttgccg ggtcttcgca
    15061 cagttcggtc agcacgccct gcgtcgattt cgggtgcagg aatgcgatat tcagcccctc
    15121 cgcgcccttt cgcggcgctt tgtcgatcaa ttgcacccct ttcccctcgc attccgccag
    15181 cgcttcggct accccgtccg ccaccgcgaa tgccaggtgg tggataccct cgccccgttt
    15241 ttcgataaac ttggcgatcg tgctctcctc cgacgtcggt tcgagcagtt cgatcttagt
    15301 ttggccgacc ttgaagaaag cggtgcgtac cttctggtcc gccacttcct cgatgctgta
    15361 acatttcagg cccagcacct tttcgtaata ggggatggcc tgttcgagac ttttcaccgc
    15421 gatgccgagg tgttcgatgt gggagatgtt cataacgtat ggatttttag tcgtttagcc
    15481 tgggcagtac gacctctgcg gccgatgttt acaaagttag ggtttgtttt tgaaataaca
    15541 acccggaaat cagtaaactt ttccgcgcaa aacggcctgc ggcgcggggt ccgaagcggg
    15601 aaccgtcacg aaacggatcg ttttgtagaa cgccccccgg tccgtcggcg tcagcgtcac
    15661 cgcgacccgg acactgtcgc ccggcatgag gggcgacttc ggccacgaag gtttcgtgca
    15721 cgtacagtcc gtccggatgt cccggatgac caggggcttg tccgaccgat tgacgcaggt
    15781 cagctccacc cggtttttgg atttgaaagc gatttcgccc atctgtatga cagaaggggt
    15841 tacggacagc gtctgggccg gcaacaggtc ccatgccgat gcgaaaagcg ccgcaaagaa
    15901 gaattttcgt atcataaata ttcacaaggc agctatatgc gactttaccc tattttattc
    15961 gtatgcttga ttttcaaatg cttccgtcct gctcctctcc ttcggagcgg ctctgccgtt
    16021 ttgcaacagg gccggttggg cagaccgtta tccgattttg ggtaaagtcg tatatactta
    16081 ccattcacaa aattaatatc tttgctcatc cgagactaat ccaaaaacac ataaaacatg
    16141 aagaaaattt cactcatcgc gtctttggct gccggagcgt tgctgttttc gtgctccgac
    16201 ccgtacaaag ggcttgaccc gaaactggcc gccgacctgc aagccaacat cgccgctgcc
    16261 ggcgagaacg gtcaggaact gctcgccgcg ctggaacagg cgcccgagaa ccagaaagaa
    16321 ggtatggctt acctgatcgc gtatatgccg gagggagacc gcgacacgct gaaagcgggt
    16381 ttcctgctcg aagaggtggg ctgggcttac aaggcccgcg agactttccc gtggacccga
    16441 accctgccgg actccgtatt ctacaacgac gtgctgccat acgcctcgat gaacgaacat
    16501 cgcgaaccgt ggcgggctat gttctgggaa aaactctatc cgctggtgga cagcatcacc
    16561 gacgtgcggg cggcgatcga cacgatcaac aagcaactgc aatacctggt taaggtggag
    16621 tacaacacca aacgtaaaaa accgcaccag tcgccgggcg aatcgatgga gatcggcatg
    16681 gcgtcgtgca gcggtctgtc gattctgctg actgacgctt tccggacgat gggtatcccg
    16741 tcgcgcatcg cgggtacgcc gttgtgggtg tcgaaagaag gcaaccacaa ctggacggag
    16801 gtctggatcg acggccagtg gtatttcacg gaatattatc cgacgccggc gctgaaccac
    16861 agttggttcc tggaacgcgc gggcaaggcc gacaagagcg atccgattta ttggatgtac
    16921 gcaacgtcgt ggaaaccgac cgggttgcat ttcccgatgg tctgggataa ggataacgaa
    16981 aacgttccgg gcatcgacgt gacggatttc tatatcgacc tgtacaacgc gcaaatggct
    17041 gaggcgaaga acggagcgcc ggtggtgatc cgggtgttca aggccgagga cggcggacgc
    17101 agcagcgccg accgcgtggc gcaggatgtg aaggtggtgg atgcggacgg caatatggtg
    17161 gctgcgggca aaacggcggg gccgacggcc gacatgaacg attacctgac gctctacctg
    17221 ccgttcggca aagagctgaa agcggagttc acggatgcgg cgggcacggt gcacagcgct
    17281 ccggtctcta cgccgaaggc ccgaaaaggc gaacagccgg cgccgatcga aatcgaactc
    17341 tatctcgaat aagaaccggt agcatatacg gcatcccgat tatacgcctt tggttttctc
    17401 ggacgcttct tcggttcgtg cctttcgtcc ggggttgcct gccatactcg attctggcgg
    17461 cgccgcagag ccggcagcgg gaaattaccg ccggacaggt ctggtatacc aaactataaa
    17521 tcaggtaccg tatgtatcga cctgaaaatc gaggcttccc ggaaacgggg agcctttttg
    17581 gtaagcgacc gtacccggcc cgggcatccg gttcgtgtgt ctgatcgtat gcggacaggg
    17641 aatcgacgga aaaggagcgg gccggagagc ggcagaagat cggacaggcg ttcgatccgg
    17701 agtaacgccg cgttccgtcc tcgccgtttc tgtcccgtgt ccgttcggat acgggcggta
    17761 tagcagggta tgcggcggga ttttcgccgg atgccggggg tctgcctgcc gccgaccggc
    17821 aaaacgacga aaagagttat atacgatggg cgaaccgccg gaaggaggtt cgcccatctc
    17881 agaaaccgtc tgtttcgggg actgccgaaa gaaagcatat gctgtccgcc ggatcgaacg
    17941 gcggagcagt cagcgtatgc ctcgccggtt cagctctttc gcatatgccg ctgcgttgcg
    18001 gttatgttcc ggcagcgttc gggcgaaagc atggcgtccc gagaagtccg ctttcgcgca
    18061 gaaataatag taatcatgtt ttcggtcttc ctccgcatat gccagcgtcg catccagcgc
    18121 cgagaccggc ggcacgcaga tcggtcccgg aggcagaccc gcataccgat acgtgttgta
    18181 cggcgagtcg tatgccaggt gccggttcag cacccgccga atcgacgggt cgcccagcgc
    18241 gaacttgacc gtcgggtccg cctggagcgg tattcccgca cgcaggcggt tgatatagac
    18301 gcccgccacc tgcgtcatct cgccgctgaa cttcgtctct tcgatcacga tcgaagcgat
    18361 cgtagagatc tgctccggcg tcaggttcag tttttccgct ttcgcccgcc gttcctcgtt
    18421 ccagaaccgg tcgtgctcct tttgcatcct ggtcacgaat tcgcgcggag tcatcgtcca
    18481 gtagacctcg taggtattcg gtatgaacag cgacggaaat gtcgccttcg tcagtcccgt
    18541 ttcgccgatg accgattcgt cgttcaatgt ccgcaggatc gccgcagaat cggcctcgat
    18601 gtatcgcgat acgactcccg ccagtctgtc cattgtgcgt atgttgttga acgtcagtcg
    18661 taccggggtt tctcgaccgt aaaagaaacg ggtcagcgcc gtgcggtacg ccatgccttc
    18721 ccggagcgtg taatttcccg cccggacgct gtccagtccg ttcgaacggg cgtaggaatc
    18781 ccatttgcgg ggggttttca ggtatccgct gtcggccagc atccggctca gttcgtcgaa
    18841 agaggttccc gtacggacct gtacggtacc ctcccgcacg atggccgtcc cgaaacggta
    18901 gtcgtattgt ttccagccga tcgcaaccgc tattgtgaga aaaaccagag ccagggccgc
    18961 gatgatcgtt atgccccgcg ccgaaagttt tcgtcgtttc ccttttgcgg aggccttgcg
    19021 gcgggcggtt tttgtttttg ccataggtgg ggatgctcct gttttgcaga gccaaaggta
    19081 cgcaaaaatc gaaaatcgcc ggccggggtt ggggaaatcc gaaaattgcc ttatttttgt
    19141 gccgtgggta agtcttgtac gaccagctcc tgctgaatcc cccagggccg gaaggcagca
    19201 agggtaggcg gttgtagcgg tgcgatgcaa gtagcttacc cactttttta tttgcgtcgg
    19261 caataatccg cgttttatgc gaatctattt attcattacc tttgggtcat gatcatcaag
    19321 ctatatcccg aaaatcccaa cgaacggacc gtaagacagg tggccgacat cctgcgccgc
    19381 ggaggggtga tcgtctatcc caccgatacg gtttacgccc tcggctgcgc gctcgaccag
    19441 cccaaggcca tcgaacggct gcggacgatc cgggggggca aggattccgc cgagatgtcc
    19501 atcgtgtgcg ccgaaatcgg cgaagcggcc gaatacgcca aagtggacaa tctggtgttc
    19561 aaactcctga aacacaacct gccggggccg ttcaccttca tcctgcccgc ttcgtcgcgg
    19621 atttccgaca aagtgatgat cggccgcaag acggtcgggg tgcgcattcc ggacaactcc
    19681 atcgcgctgg cgatcgtgcg cgagctgggg atgccgctgg tgaccacttc cgtgaggacg
    19741 gacgacgtgg gggacgaagt ggagtatatc accgatccgg aactgatcag cgaacgctat
    19801 ccggcggtgg acgccgtgat cgacggcggc atcggcgaca atttcgcctc cacggtggtg
    19861 gactgcacgg tcagcggcga ggtcgatgtc gtgcggcagg gacgcaggga actcgaattc
    19921 tgaaaattta tggacgaaca aacacgcaaa cagaaataca ggggagaatt gctcacggcc
    19981 ggcatggtct tgggactggt catgttcgcg gtcgtggtat tgcaatacct gttccgcgac
    20041 gcgggcggtt ttgtggtcgg cttgctctcg ttcgccaatt tcgcggcgat cgtggcggtg
    20101 ctgatcgttt acggaaggcg cgctgcggcc ttgtgcccgc ccgatcccgt gctgcggccg
    20161 aacggattta cttacggccg ggctttcgga ttttcgatac tcgtttcgtt gctgagcggg
    20221 atcgtgtacg gggtcggtta tttcctgctg accgaggtga tcgatccgcg ctatttcggc
    20281 cgggccatgg aacgcgtggc cgagctgtac atttcgtcgg ggctgatgac cgccgagcag
    20341 gtgcaggcgg gaatggcgtt gatgcacaac cttttcgtcg tgattttcgc caatatggtc
    20401 gccatgttgt tccagggcgg tttcctgtcc ctgttcactg cggcgatcgt gcgttaccgc
    20461 aggccgcaca gttcgtttcc gccgttgcaa taaaatgatc gacatggata tttcgctggt
    20521 cattccggta tataacgaag aggagtcgct cgcgcccctg atggagtgga tcgcccgtgt
    20581 gatgggagat cacgggttct cgtacgaggt gatcttcgtg gacgacggat cgacggatgc
    20641 gtcgtgggag gtcatcacgc gtttgaaagg gcagtatccg gcgattcggg gtatccgttt
    20701 ccgccggaat tacggcaagt cgcccgccct ttactgcggt ttcgatgcgg cgcaagggga
    20761 ggtggtcgtt acgatggacg ccgatttgca ggattcgccg gacgagatcc cggagcttta
    20821 ccggatggtg accgaagagg ggtacgacct ggtgtcgggc tggaaacaga aacgttacga
    20881 cccgctgggg aaaacccttc cttccaaatt tttcaacatg acggcccgcg tgaccagcgg
    20941 catccggctg cacgacttca actgcgggct gaaagcctat aagaagaagg tggtcaagtc
    21001 gatcgaagtc tatggcgaga tgcaccggtt cattcccatt ctggccaaac aggccggttt
    21061 ccggcggatc ggggagaagg tagtgcagca ccgcgcccgg cagttcgggg tgtccaaatt
    21121 cggctgggaa cggatgataa aggggtatat cgacctgctg acggtgcttt tcatgacccg
    21181 tttcggacgg cggccgatgt atatcttcgg cggcatcggc acgctgatgt tcctggtcgg
    21241 ggcggtcatt accgtttacc tgatttccga gaagctgtat ttgcaacatc acggccttcc
    21301 gctgcggccg gtaaccgacc agccgctgtt ctatatcgcc ttgctggcgg tggggctggg
    21361 cgtacagacc tttttggccg gcttcctggg agagatggtc aatcgttcgg cgccggaacg
    21421 caaccggtat ctggtggacg aacggctgtg acgattgttt gtaaggcggc atttcggact
    21481 gccgtcgttt tttcgttgag gtagtgaggc cttccggtcg gagggacggg cgccggcggt
    21541 tctgtgaatc gtatccgtcc ggcgcattta acgaagagaa aaattgtacg gttttaaaaa
    21601 atttattaaa attgcagtcg gaacagtggg tttcctctga tcctcggatt taccaacaac
    21661 acaataaaaa ctcaaagtta tgtctaaaat caaagtaggt atcaacgggt tcggccgtat
    21721 cggtcgtctg gtgttccgcg ctgcgctgac caaaagcgac atcgaaatcg tagggatcaa
    21781 cgacctcgtt ccggtggatt acatggcgta tatgctgaaa tacgacacca tgcacggcca
    21841 gttcaaaggc accatcgaag tcaaggacgg caagctggtc gttaacggcc aggctatccg
    21901 cgtgactgcc gaaaaagacc cggccaacct gaaatgggac gaagtgggcg ccgagtatgt
    21961 cgttgaatct accggtctgt tcctgaccaa ggagctggct gaaaaacaca tccaggccgg
    22021 tgccaaacgc gtggtgatgt cggctccgtc gaaagacgat accccgatgt tcgtgatggg
    22081 tgtgaacaac aaggaataca aaggccagac catcgtgtcg aacgcttcct gcaccaccaa
    22141 ctgcctggcc ccgatcgcca aagtgctgaa cgacaagttc ggtatggtag acggtctgat
    22201 gaccaccgtt cactcgacca ccgctaccca gaaaacggtg gacggcccgt cgatgaaaga
    22261 ctggcgcgga ggccgtgccg ctgccggcaa catcatcccg tcttcgaccg gtgccgccaa
    22321 agccgtgggt aaagtgatcc cggcgctgaa cggcaaactg accggtatgt cgctgcgtgt
    22381 tccgaccctc gacgtttcgg tagtcgacct gacctgcaac ttggccaaag acgttaccta
    22441 cgacgaaatc tgccaggcta tgaaagaggc ttcggaaggc gaactgaaag gtatcctcgg
    22501 ttacaccgaa gatgctgtcg tttcgagcga cttcctgggc gacgcccgca cttcgatctt
    22561 cgacgccaaa gccggtatcc agctgactcc gcgtttcgtg aaggtcgttt cgtggtacga
    22621 caacgaatgg ggctactcga acaaagtagt cgaactgatc cagcacatga acaccgttaa
    22681 ataatcttta cggttcgtcg ttttacaggc gcggcccaca tcgttttcga tgcgggccgc
    22741 gctgattttt tgcgtcggat ggcattccgt tcgttccgga ccgtattttc ggttccgatc
    22801 ttcaggaggt tttcccgcgg ttcctgtttc agaacggaaa caacgaaaga cgacctgcat
    22861 tgtccgggtg gctggcggcg caggtcggtg ttgggttagg cggctatgtc ctttgctttg
    22921 gcttttcggc ctgcaccggc cttttcggac ttgtgtcgtt tcgtccgacg acggtacggc
    22981 atgggggcgg tctcgatcgt tattgcgtaa atcctgcgtt gagttttccg ttaggtaaat
    23041 atatacgact ttaccctata attatatgca tacttgattc tcagcatatt tcggcccgcg
    23101 cccacccccc gaagccgcaa agcggcttgg gcgcagggcc gtttagggag attgttgccc
    23161 gattttgggt aatgtcgtat atacttactt tccgttattt atggtagagc agtacggtgg
    23221 catagacggc tacgccttct tcgcgcccgg taaaaccgag ccgttcggtg gtggtcgctt
    23281 tgatcgaaat atcttcgacg gcgctgccga gcagcggggc aagggttttt cgcatcctgt
    23341 cgatataagg ccgcaacttc ggagcctggg ccagtatcgt gcagtcggcg ttccccagtc
    23401 ggtatccttt ttcctgtacc agtgcgatgc atcgcctgag caatattttg ctgtctatat
    23461 ctttgaattc ctgtgcgttg tctgggaaat gaagccctat atcccccagg gcgagcgctc
    23521 cgagcagggc gtcgcacagg gcgtgtatca gaacgtcgcc gtctgaatgg gctacgaagc
    23581 ctttattatg ttcaatgcga atgccgccta accacatggg cagtccctct gctaaagcgt
    23641 gcacgtcata cccgttcccg atacgtatcg tttccatttc tttttattat ttttattcgt
    23701 tcgtttattc gtattgaggc aaccgctagg ctcaggagat gcgaagcatc tcaaaaagtt
    23761 tggcttcgcc ttcctcctga cgcctcggcc attcgaacga gttcgacggc actcggctgc
    23821 tgcgtcggtt ttctggttct ctttgttcac aaccgacgct gccagcgaat ccagagaccg
    23881 tttacgggct atggtaagcg gcgaggagga accgagtagc gttccgagac caaagaccgt
    23941 tcacggtctt tggcaaggta gcacgaggaa gccgcaggca aaacgagcgt agcgaagtta
    24001 aagagaacag tatcttcaaa ccaaaaagta ccaaataaac gaacgaataa aaataataaa
    24061 aagatgaaga agatagcaga gcttgaaccc cggattgtct ggaagatttt cgaggagatt
    24121 acgcgcgtgc cccgtccgtc caagaaagag gttaagatac aggcctttat cgaatccttt
    24181 gccgatgcgc acgcattgga gcgcaagcgg gatgtcaaag ggaatatcgt cattgtccgg
    24241 cccgcctcgc ccggacgcga agacgaaccc gccttgattt tgcaaagcca tatggatatg
    24301 gtgtgcgaaa aagattccga catacggatc gatttcgaga acgaccctat cgaagcctat
    24361 gtggacggcg aatgggtcaa ggccagggga accaccctcg gagccgactg tggtatcggt
    24421 atggccctgc aaatggcggt tttgatcgat cccgaactgc acggcccgaa aatagaagcc
    24481 ctcttcactg tcgatgaaga acagggtctg accggggcga tgaacctcgg cgaggggatg
    24541 ctgaccggaa accggatgat caatctcgat tccgaagacg aaggcgagat tttcatcggc
    24601 tgcgccgggg gaatcgatac cgtcgctacc ctgacatatg cgccggaacc ggctccatct
    24661 acgcctgatt acgagtatta taccatcgaa gtttccggac tgcacggcgg acattccgga
    24721 gacgacatcg aaaaaggatt tgctaactcc aataaagtgc tgaaccggat cctgtggaac
    24781 ctggctcgga agcacggtct gcgtttgagt cgtttcgacg gaggcaattt gcgcaatgcc
    24841 attccgcggg aagcgcgggc gctcgcagcc cttcctgccg ggcaggttgc cgcggccgga
    24901 accgcgttcc gaacactggc cgatgaaatt atccgggagt tcgcctatac cgaaacttcc
    24961 atgcgcataa cgttcgaacc ttcagcggag agacccgtcc acgcgctgcc tgcggatgca
    25021 cagtcgcgtc tgctgcaagt gctgtatgcc gttccccacg gagttatggc gatgagtttc
    25081 gcgatgcccg gactggtgga aacttcgacc aacctggcct ccgtgaagat gccggaagag
    25141 ggtaggatcg tgattacgac ttcgcaacgc agttcggtgg agagcgccaa gcgcgacata
    25201 gccgaccggg tggccgccgt gttcgctttg gcgggggccg aagtacggca tacggacgga
    25261 taccccggct ggtcgccgaa tcccgcttcg ccgctggtgc gcaaatcgtc cgccatatac
    25321 agggagatgt tcgggcgcga cccgaaagtc agggccattc atgcggggct ggaatgcggc
    25381 ctgtttctga cccggtatcc ggaactcgac atgatttcca ccggtcccac cttgcgaggc
    25441 gtgcattctc cgg
//
