LOCUS       NZ_CP072339.1          23985 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP072339.1 Prevotella nigrescens strain F0109 chromosome 1,
            complete sequence.
ACCESSION   NZ_CP072339
VERSION     NZ_CP072339.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:18:17
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2059149
            Orig. end    :: 2083134
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23985
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2069149:2073134]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13985
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..23985
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23985
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_fatty_acids"
                     /region_number="4"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             860..2032
                     /locus_tag="ctg1_1765"
                     /transl_table=11
                     /translation="MHTISRFIEHALLSLNVEHTTAYVIRHALLVVIVFLLAFLAGFLC
                     RKVLVPLVTKLTSKTSLEWDSVLFDKTALYTACSIVPAVVIWELLPKVFFQYPLVEDAL
                     LRLTAVYIAINSTRLVLQIVDRLRYLRQSEGSAGSQYLRSFLGVLRIIVIFIAVIVVIS
                     ILLNKNPMSLFAGLGATSAVLMLVFKDTIEGLVAGIRLTSNEMVHVGDWITVPGTPVDG
                     NVVDITLTTVKVRQFDNTYTTVSPLTLVNGSFKNWQGMTDSGMRQVVKRIYFDVHSIRL
                     LNSETRQNLTDKNMVAPEETEGEVVNIGLFRHYIETYLRKRDDVSKSATLLVRQLEATQ
                     SGVPIELYFFIGTTDWVSYEQKTSDILEHIYAYANEFGLQIYEGLPVANT"
     CDS             2202..2606
                     /locus_tag="ctg1_1766"
                     /transl_table=11
                     /translation="MIEFEIKSKIQLIGKRKGQTVYFAQATAQQHLTSNMVIDRIVRET
                     SLSAGDVSNAIISLSAVVRDALESGQSVDLADLGSFRIMVPSKMMDSEKEVTAESLKTP
                     KIIFTPKAAMRAAANSVELRVIRKGGDKER"
     CDS             complement(2724..3572)
                     /locus_tag="ctg1_1767"
                     /transl_table=11
                     /translation="MKKLSNFVWLLAIALGAAIALTACSKNSDGPDGGEDKGKVEVNPT
                     KVFVNGMPKIVDGSVFTRDFKGRLSSIYNREENVLIAFAYTSSILGTKDVPNVVMTVTD
                     ADERTVYNLFLNKDGFVKYCDEIDYEEKGNTPKTTTWNFEYNSDGQLIKAVQSKDGVKT
                     SSTIAYNDGDAVETVTMSEKDGKETDHYRIYYTSKKVTSPIENRGCIMSFDVALGLDLD
                     HLQIAYFAGMLGKATKHLPIYNMDKDNDKTTFDWILNGNGFPTKVVVKDDGGREESNFV
                     W"
     CDS             complement(3596..3985)
                     /locus_tag="ctg1_1768"
                     /transl_table=11
                     /translation="MRRRILLDYLMSMLPVGSMLLVGCAGLSKKGGAANDDTLSVMGRW
                     TTEMPADSAAEMGIELKADGVAASVNMPTLPYDRWQKVNDSTVAIHGTSIFDGERTELT
                     DTFHIDKEKQTLNQQGTDIVYRRAN"
     CDS             4208..5383
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AICARFT_IMPCHas"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1769"
                     /sec_met_domain="AICARFT_IMPCHas (E-value: 5.4e-61,
                     bitscore: 203.4, seeds: 747, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKELELKYGCNPNQKPSRIFVDEGELPIEVLNGRPGYINFLDALN
                     SWQLVKELKEATGMPAAASFKHVSPAGAAIGLPLSDTLRKIYFVDDFELTPLASAYARA
                     RGADRMCSYGDFCALSDTCDEATARLINREVSDGVIAPDYTPEALHILKKKRKGNYNVI
                     KIDPTYKPAPIERKQVFGITFEQGRNEIRLDEPKLFENIPTTNKIFPEEARRNLVIALI
                     TLKYTQSNSVCYVKDGQAIGIGAGQQSRIHCTRLAGNKADEWWLRQCPKVMNLPFKDGI
                     RRADRDNSINVYISDEYEDLLQEGTWQLFFTEKPEPLTLTERKAWIAQNKQVALGSDAF
                     FPFGDNIERAHKSGVEYIAQAGGSIRDDHVIETCNKYGIAMAFTGVRLFHH"
     CDS             5419..5604
                     /locus_tag="ctg1_1770"
                     /transl_table=11
                     /translation="MSDIDEIIENGMVFRGAPKAKADDGKIKTKAKKKKYITGAHGSGS
                     AKQKAKYRQQRANRHK"
     CDS             5765..6217
                     /locus_tag="ctg1_1771"
                     /transl_table=11
                     /translation="MKKVFILMAVCATMVACQQKGKQNADAKAGDTTKVEATDSMRYAG
                     EVPAADGPGIRYEIALANDSTNGFSIKETYLKAEKGKDKVLNYTGKAEKIEKDVKGQKK
                     VGYKFTTGKDDALYFLQANDSTLRMVNDQLEEAATKDLNYDLKLVK"
     CDS             6766..7812
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1772"
                     /sec_met_domain="Fe-ADH_2 (E-value: 2.2e-11, bitscore:
                     40.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQQIVFTHKFEQSLSDSIAKCNPDKIFVLADDTTIGMCYNRIKH
                     FECLKKAQPITIPSADVNKNLSSLSCVWKVLQTAKATRHSMLINLGGGMVTDLGGFAAA
                     TFKRGINFVNVPTTLLAMVDASVGGKTGINFDGLKNEIGAFAFPQTVIIDTQWLGTLDR
                     ENLLSGYAEMLKHGLIAEKGALATLLAFDTDTFNLRQLAEMLKESVEIKEKIVEQDPHE
                     KHIRKALNFGHTFGHSFEAWAMTRKPILHGYAVAYGIVCELYLSVVKQGFPTDIMRKTV
                     NFIKANYGEFAISCNDYDALIDLMKHDKKNVNSTINFTLLQDLGRVSINQTATEDEIKE
                     ALDFLREG"
     CDS             complement(7870..8886)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 66.6; E-value:
                     5.5e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1773"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-19, bitscore:
                     66.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLEQFLSEWHSEDPTLLVHTSGSTGQPKPLRVEKARMLNSARIT
                     CDFLKLRPNDTALLCMPLDYIAGKMVVVRSIERKLRLLNVKPSGNPLSDASLAQLSNPD
                     EPITFAAMVPLQVFNTLQNSKERKRLQRIRHLIIGGGSIDNELSAQLKDFPNAVWSTYG
                     MTETLSHIALRRLNGSESSDWYTPFDGVEVSLNDDGCLVINAPAVCSQRLETNDIAELR
                     LTEAGRAEFRILGRKDNAINTGGIKVQMEEVEQALRPYLAVPFLITKRKNKKFGEEIVL
                     LTETNDLEEVRAACVKALPRYWQPAHYQHTDQLPTTETGKIARAKALQMVDQPTDME"
     CDS             complement(8945..9994)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1774"
                     /sec_met_domain="MR_MLE_C (E-value: 1.1e-26, bitscore:
                     90.7, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKITITSKLLHFLQPAGTSRGVYNTRLSFYLKLTSDEQPDVVGV
                     GECATLPDLSCDAMPPNEYERKLRTFCDEYERTGVIDYEAMRAYPSMLFGLETAVAQFN
                     AKGSLNFFDTPFGRGEEGIPINGLVWMGTFEEMFERLEAKLKAGFRCIKIKIGAIDFDR
                     ELQLIRHIRSTFSRNDVELRLDANGGFTPEEALSRMEALVQYDIHSIEQPIKQNQWTEM
                     ARLCTATPLPIGLDEELIGVNERQKKIELLDTIRPQYIVLKPSLHGGMAGTEEWIQLAR
                     ERNIGSWITSALESNVGLNAIAQLTASIYGTNIRHAQGLGTGQLFADNIEMPLKVIGDK
                     LWIMQQLHN"
     CDS             complement(10001..10828)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1775"
                     /sec_met_domain="ECH_1 (E-value: 1.7e-80, bitscore: 266.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANREWKTIEGFDFKEILFEEYNHIAKITINRPRYRNAFTPLTVW
                     EISQAFSYCREALNIRVVLLTGAGDKAFCAGGDMNVKGRGGYVGGDGVPRLNVLDVQMQ
                     IRRLPKPVIAMVNGFAIGGGHVLHVMCDLSIASENAIFGQTGPKVGSFDAGFGASYLAR
                     IVGQKKAREIWFLCRQYSAAEAERMGLVNKVVPFDKLEDKCVEWAETMMERSPLALRMI
                     KAGLNAELDGQAGIQELAGDATMLYYTMDEAQEGGRAFLEKRKPDFDKYPQFP"
     CDS             complement(10846..12516)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1776"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.1e-07, bitscore:
                     27.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSNKENVNILTALLVQHGITQAVVCPGSRNSPLVHNLCECKDIK
                     CYPVTDERSAAFFALGVAISTHSPVVVCVTSGSALLNVAPAVTEAYYQNLPLIVVSADR
                     PQQWIGQSDGQTMPQANALAPFVRKSVHLIEPKTKEEHWYCNRLVNEVLIECKRFAYAP
                     VHINVPISEPLFDYDVATLPTERHISATSVCNDNAAVADVVTMVRQAQRPLLIIGQEAW
                     ADMTEVKAELVRLRQHIVVIQDKLSDVTDTAPQLVDAAITIAEDTEALRPDLIIYMGGT
                     LVSKQCKQFLRSCTPKDSILIDPRGDIRDTFTNLTAVVQCQSDAFIKALASGLEDFATS
                     KFYHGWQKALNNAAATAQSYVPTYSQMLAVKRFHTLLQQNNDAKALVYGNSSAVRLGNF
                     FSSDYIFVNRGVNGIEGTLSTAVGMAAANKDKRVFCAIGDLSFFYDQNALWNSNLGDNL
                     SILLLNNSGGGIFQQLSGLEKSAHRAAIMGAGVSVTAKGVCQTHNIGYLSATNSEELEN
                     CLAAFLNIRKSSVLLEVFTDPEKDAKAWSTFYKQLEKKQ"
     CDS             complement(12532..13548)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1777"
                     /sec_met_domain="Chorismate_bind (E-value: 8.3e-53,
                     bitscore: 176.4, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSFAVYRLPFAEECTMLVQHSAPSELSSLTELDGKEGFVIAPFS
                     PSADCPILLLQPDEVRMMPVKEVQSLAKEKQEASEKEADRAKYHRDFAAFHKELANNKF
                     AKIVLSRCVQEQIPHDLQPEEVFWQACKKYPRQFVALFSTPQSGIWLMATPEILLDGNG
                     TEWRTMALAGTMPYNENGIEWSAKNKAEQQYVSLYIKRCLERCADEIKEEGAYTTQAAD
                     LVHLRTDFSFKLRPDAAIGQLLSDLHPTPAVCGMPKDETKAFILANESNKRLYYSGFAG
                     PLNLQGNTHIYVSLRCMQMQTGVCNLYAGGGILKESTEESEWKETEAKLSTMRQLLR"
     CDS             complement(13566..13985)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1778"
                     /sec_met_domain="HBT (E-value: 1.9e-13, bitscore: 47.5,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVEKYSAILENEEGLSRTLGMHFISTPEPDTLMAKMAVGDRNRQ
                     TFGFLSGGATLALAENVAGLGSMVLCDGKMALGINVSGNHVKAVPYGGMVTAYARILHQ
                     GYKLHVWHIDVKDDEGELISSVQVTNYIVHSNRKL"
     CDS             complement(14338..16089)
                     /locus_tag="ctg1_1779"
                     /transl_table=11
                     /translation="MKKILISMLLSAAITLPTLAVGPMPKVWTVKQSDSTSIKIMVRGA
                     GGRTVYYTTLDGKILSKGANNSFYYAVIRDGKLQPSALIAHEAGDRTAEEKAFLDANKT
                     EKNMHLLKSVAKRTAHNAPLKAISASTADGLGEYNRSGMGGINSIGTPLVPVVMVEFKD
                     KDFLSTTTPEKMMRYYNEAGYHDEPGCVGSVKDFFESQSRGMFVPTFEVIGPIKVNHSY
                     AYYGRDEKTAELVRDVVKEAKAQNISFDKFKNAKTGHVELICLFYAGRGQATEDPNKPG
                     YENYIWPQEQDINETIEGIPFNSYFVGNELNYYGTLMGMGVFCHEFGHALGLPDFYNTD
                     PSVTLSRNPFGYWSIMDAGPYVNNANAPIGYTAYERSYLGWLKIKELTSPQTVKLDPVS
                     NRNGELAAIVRSTRNRAEYFILENRTSDTWYPKAYKERRANGYETFTFGDGLMLSHFAY
                     TKGTWETNSVNTVDSKMRAYIIPADDEQLNYSAHKENLFGVEKKNIDKLTFYDGLTVNN
                     AIQGIEVNADGTILFGYRQQPNAIENISETTTENAGDGYYYDLQGRRVLNPTRGIYIHN
                     GKKIVVK"
     CDS             complement(16333..16833)
                     /locus_tag="ctg1_1780"
                     /transl_table=11
                     /translation="MTEFRTMRRKRQELTETECTEILEKATSGVLSLLGDDGYPYGVPI
                     TPVLVGRKLYFHSALKGHKLDAIHNSNKASFTVIDRNEVKPKEFTTYFRSVICFGKVRL
                     IEDETEKMEALCKLGRRYNPDDEEGLRHEIKKDFSHLVMIEFTIEHISGKEAIELVRMK
                     KAR"
     CDS             complement(16852..17235)
                     /locus_tag="ctg1_1781"
                     /transl_table=11
                     /translation="MKYQTSRNFKITMALALIAGYLFTTMLCYYLFRSNDFDFFAVFWF
                     LGTIAIFIAYYYRMTIKIEGNLLTYKTTNEVKTRTLPLSEIATVSIRKKLFYPVLTITT
                     KQQTKIHLYPEQPEQLEKALIVQ"
     CDS             17821..19590
                     /locus_tag="ctg1_1782"
                     /transl_table=11
                     /translation="LQIIKIIIRLIEKMNVLELSEQEIVRRQSLQELRNMGINPYPAAE
                     FPTNAYSTDIKKEFKEDEKREVVIAGRLMGKRVMGKASFAEIQDSKGRIQVYITRDDLC
                     PGENKDLYNIVFKKLLDIGDIIGIKGFVFKTQMGEISIHAEKLTVLSKSLKPLPVVKYK
                     DGVAYDKFDDPELRYRRRYVDLVVNDGVKETFKKRATVLRTMRRFFDDAGYTEVETPIL
                     QTIAGGASARPFITHFNALNTEMYMRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRF
                     HNPEFTCMELYVQYKDYNWMMSFTEKLIEKICTEVNGKPEIQVGDNLISFKAPFRRLPI
                     LDAIKEKTGFDLDGKTEEEIRNIAVNELKIEGIDNSFGKGKLIDEIFGEFCESTFIQPT
                     FIIDYPVEMSPLSKMHRSKPGLTERFELFANGKELANAYSELNDPIDQEERFKEQMRLA
                     DNGDDEAMVIDQDFLRALQYGMPPTSGIGIGIDRLVMLMTGQEYIQEVLLFPQMKPEAK
                     VPQSSIKEWAEIGVPEEWVYVLRKCGFNLIQNIKEEKAQGLQQKLGEINKKYKLGYDKP
                     SVDEIQRWIDKAQ"
     CDS             19608..20627
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1783"
                     /sec_met_domain="F420_oxidored (E-value: 1.2e-05, bitscore:
                     22.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 3.1e-34,
                     bitscore: 115.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VPFSLEYDMYDVGNIAIIGSGSWATAIAKIVVEHTHHIGWYFRRD
                     ETIEQFRKLGHNPTYLTSAHFDTNEIRLSSDINRLVQDYDTLIFVTPSPYLKGILKKVK
                     HKLHDKFIVTAIKGIVPDENLVCSEYFRKVMKVPEENLAVIGGPSHAEEVAMERLTYLT
                     VGCTDTEKAQALTEVLVSNYVKTKVSHDVLGIEYASVLKNVYAIASGICSGLKYGDNFQ
                     AVIISNAMQEMERLLTSINPIKRNMIDSVYLGDQLVTGYSNFSRNRTFGMMIGKGYSVK
                     SAQMEMEMIAEGYFGTKCMKEINRHLHVNMPILDAVYNILYEGISPKIEIKLLTDSFR"
     CDS             20635..21981
                     /locus_tag="ctg1_1784"
                     /transl_table=11
                     /translation="MENIKLDISKAAQVLNPGTMESYAPQVAAAQEALEKGTCLGNDFL
                     GWLHLPTNITEEFINEINSVAGTLREKCDFVVVAGIGGSYLGARAIIEALSNSFAWLLN
                     DKKNPTILYAGNNISEDYLYELTEFLKDKRFGVINISKSGTTTETALAFRLLKKQCENQ
                     RGKEEAKHVIVAITDAVKGAARTAATREGYKTFVIPDNVGGRFSVLTPVGLLPIAVAGF
                     DIQQLVKGAQDMEKATGTDVPFAQNIAARYAAIRQALYSEAGKKIEIMANFQPKLHFMA
                     EWWKQLYGESEGKEQKGIFPAACDFTTDLHSMGQWIQEGERSIFETVLSIEEPNRKLLF
                     PHDDENLDGLNFLEGKRVDEVNKMAELGTRLAHVDGGVPNIRISIPKLNEYYIGQLIYF
                     FEKACGISGLVQQVNPFNQPGVEAYKKNMFALLDKPGYEEESKAIRKRL"
     CDS             22016..22786
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1785"
                     /sec_met_domain="HAD_2 (E-value: 8.8e-24, bitscore: 81.4,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LGFLVLHVRMFQEAIRKYNKQAAQPFAPKVVLFDMDGVLYDSMPN
                     HAKAWQRAMAEFGIHFTAEDAYATEGARGVDTVRRYAKEQLGKVLTEQEAEEMYQLKAC
                     YFQEMPTTDIFDGVKDLMQKIQNNGLKIGIVTGSGQRQLINRLLSDFKDFINETQITTA
                     FDVKRGKPNPDPYLMGLKKAGNFAPHEGIVVENAPLGVRAGVTAGCFTVAINSGPLPDS
                     ALLNEGADVLFETIRAFSDSWEQLTASVAQSLKR"
ORIGIN
        1 ggtttccaac accgacatca cagccattgc gcaggccata aaagccctga acataaccag
       61 gataaatggc aacatctacg ccgaccagtc gtttaaggac agagacgaat taggcagcgg
      121 ctggtgctgg gacgataaga accccaagct cgtcccgctg cttctgggca gccacgacaa
      181 ctttgtcggc acgctctacc gccggctgcg cgagacaggc gtagaacccg gtggagtgat
      241 gggcgaacgc acactgcctg ccgacggcac gacgctcata actacttgca cacacagcat
      301 cggcgaggtg atggacacca tgatgaagaa gagcaacaac ctctatgccg agtcgatgtt
      361 ctaccagctg gcagccgcca acggaggcag atggaactcg gcaaggcagg cacgcagaga
      421 ggtgaacgca ctgatacgca agttgggctt gtcgccgtcg gactacaaca tagccgacgg
      481 ctccgggctt tcgctctaca actatgtcag tgccgagctc gaagtgcagc tgctgcgctt
      541 cgcctacagc cagccagaca tttacaacac cctgctgcct gcactgcccg ttgcaggcat
      601 ggacggcacg ctgagaaagc gcatgcgtgg cacgcccgca cagggcaacg tgcaggcgaa
      661 gacgggcacg gtgtttggcg taagctcgct ggcaggctac cttacagcat ctaacgggca
      721 caggctctgc ttctccatca tcgtaaatgg cggcatgcgc cagagaccaa tgcgcaactt
      781 gcagaacaag gtgtgcgtgg cactgagcca gtgacataga aaagaacaaa cataaaacaa
      841 ccaaccaaaa cataacgtca tgcataccat cagcagattt atagagcacg cattgctttc
      901 gctcaacgta gagcacacca ctgcctacgt catacgccat gcgttgttag tagtcatcgt
      961 cttcctcctt gcgttccttg caggcttcct ttgccgcaag gtgcttgtgc ccttggtaac
     1021 aaagctcacc tcgaagacaa gtctcgagtg ggactccgta ctgttcgaca agaccgccct
     1081 gtacacggcc tgcagcattg tccctgccgt agtcatctgg gaactgctgc ccaaggtgtt
     1141 cttccagtat ccccttgtgg aagacgccct gctgcggctg acggctgtct atatagccat
     1201 caactccacc cgtctggtcc ttcagattgt agaccgcctt cgctacctgc gacagtcaga
     1261 aggcagtgcc ggcagccagt acctccgttc gtttctgggc gtgctccgca tcatcgtcat
     1321 cttcatagcc gtcatcgtgg taatcagcat cttgctcaac aagaacccca tgtcgctgtt
     1381 cgcaggttta ggtgcaacgt cagccgttct gatgctggta ttcaaggaca ccatagaggg
     1441 actcgtggct ggcatacgcc ttacgagcaa cgagatggtg cacgtgggcg actggattac
     1501 cgtgcccggc acacccgttg acggaaacgt ggtggacatt acccttacaa cggtgaaggt
     1561 gcggcagttc gacaacacct atactaccgt ctcgcccctc accttggtaa atggctcgtt
     1621 caagaactgg cagggaatga cggacagcgg catgcgacag gtagtaaaga gaatatactt
     1681 cgacgtgcac agcatccggc tcctcaacag tgagacaagg cagaacctga ccgacaagaa
     1741 catggtcgcg ccggaagaaa cggagggcga agtggtgaac atcggactct tccgccacta
     1801 catagaaacc tacctgagga agcgcgacga cgtaagcaag tcggcaaccc tccttgtccg
     1861 ccagttggaa gccacgcaaa gcggcgtgcc catagagcta tacttcttca tcggtactac
     1921 cgactgggtg agctacgagc agaagacgtc cgacattctc gaacacatct atgcctatgc
     1981 caacgagttc ggactacaga tatacgaggg acttccagtt gcaaacacat aacacctccg
     2041 attgcccata cggggaagcg acttaggaca ccctcacgag ggtatcaatc aacaccctcg
     2101 tgagggtatc aaccaatacc ctcgtgaggg tattcagaaa cgagaacaat aaacgggaaa
     2161 gaacaacgtt aagtaagtga taaaataaac aactaagagc tatgattgaa tttgaaataa
     2221 agtcaaaaat acaacttatc ggtaagcgca agggacagac ggtgtacttc gcccaagcca
     2281 cagcacaaca acacctgaca agcaatatgg tgatagaccg cattgtgcgc gagacatcgc
     2341 tctcggcagg cgacgtgagc aacgctatca tcagtctcag tgcagtcgtg cgcgatgcgc
     2401 tcgaatcggg gcagagcgta gacttggcag acctcggctc gttccgcatc atggtaccat
     2461 cgaagatgat ggacagcgag aaggaagtaa cagccgaaag cctgaagacg cccaaaatca
     2521 tcttcacgcc aaaggcagcc atgcgcgccg ctgccaactc ggtggaactc cgcgtaatca
     2581 ggaagggagg cgacaaggaa cgctgactga gactccgctt gcagaacaaa acgtaccact
     2641 cggctccaca caacgacaag ggcaacgaaa cattcgcttc gttgcccttg gttcacttta
     2701 tacgacttca gccttatata tctctaccag acaaagtttg attcttctct tcctccatcg
     2761 tctttaacca caaccttggt tgggaatccg ttgccgttga ggatccaatc gaaagtagtc
     2821 ttgtcgttgt ctttatccat attgtatatt ggcagatgct tggtagcttt tcccaacatt
     2881 cctgcaaagt aggcaatttg caaatggtcc aggtctaacc ccaaagctac gtcgaaagac
     2941 attatgcaac ctctgttctc gataggcgaa gtaacctttt tagaagtata gtaaatcctg
     3001 taatggtctg tttccttgcc gtccttttcc gacatggtta ctgtttctac ggcatcgccg
     3061 tcattgtaag caatggtaga cgatgtctta actccatctt ttgactgcac agccttaatg
     3121 agctgtccgt cagaattgta ctcaaagttc catgttgtcg tcttgggagt attgcccttt
     3181 tcttcgtagt cgatttcgtc gcagtatttc acgaatccat ctttgttcag gaacaagttg
     3241 tacacggttc tttcatcggc atcggttact gtcatcacca cgttaggcac atctttggtt
     3301 cctaagatgc tgctggtgta ggcaaatgca attaagacat tctcctctct gttgtatatg
     3361 gaagacaacc gccccttgaa atcccgtgtg aagacgctgc cgtcaactat tttaggcata
     3421 ccattgacaa agacctttgt agggtttacc tctactttac ctttgtcttc gcctccgtcc
     3481 ggaccatcgc tgtttttact acacgctgtt aatgcaattg cagcacctaa ggctatcgcc
     3541 aggagccaca caaaattaga taatttcttc atcgtttcta tattattgtt gttaattaat
     3601 ttgcacgtct gtacactata tcggtacctt gttgattaag tgtctgcttt tccttgtcta
     3661 tgtggaaagt gtcggtaagt tctgtcctct cgccatcgaa gatacttgtt ccgtgaatgg
     3721 caacggtgct gtcgttcacc ttttgccaac ggtcgtaagg caaggtcggc atattgacag
     3781 aggctgccac gccgtctgcc ttcagctcga tgcccatctc tgctgccgag tcagcaggca
     3841 tctcggtagt ccagcgaccc atcacgctaa gggtatcgtc atttgctgca ccgcctttct
     3901 tggataaccc tgcgcaacct acaagcaaca tggagcctac aggaagcatg gacattagat
     3961 aatcaagcaa tattcttcgt cgcatatcgt aatgtttaag tcattttgtc ggcaaagata
     4021 tacataaatg cccacactgt ggcagattgc tttctaaaaa aactaaacaa tagtttaatt
     4081 tcttttatat tagtcgcctg acaaacaatc tataaaaata tggaactata gtttagaaat
     4141 atcgttttat ttgtctatct ttgcaacttc aataaaggtc tgtcattcat atatacatca
     4201 ttgaactatg aaagaattgg aacttaaata tggttgcaat cccaaccaaa agccttcgcg
     4261 catattcgta gacgaaggag agttgcccat cgaagtgctg aatggtcgtc ccggctatat
     4321 aaactttctt gatgcactca acagttggca attagtgaaa gaactgaaag aagccacagg
     4381 tatgcctgcc gcagcatcgt ttaaacatgt cagcccggct ggagcagcca ttggtctgcc
     4441 attgagcgat acattaagga agatatactt cgtagacgac ttcgaactta ctccgctcgc
     4501 ttcggcgtac gcacgtgcca gaggtgccga ccgtatgtgt tcgtatggtg atttctgtgc
     4561 actgagcgac acttgcgacg aagctaccgc ccgacttatc aaccgcgagg taagcgatgg
     4621 tgtcatagcc cctgactata cgccagaggc tctccatata ctgaagaaga agcgcaaagg
     4681 caactataat gtcataaaga tagaccctac ctataaacca gcccccatag aacgcaagca
     4741 agtgttcggc ataactttcg aacaaggcag aaacgaaatt cgactcgatg agcctaaact
     4801 cttcgagaat attcctacta caaacaagat attcccggaa gaggctcgtc gtaatcttgt
     4861 catagcactt attacgctaa aatatacgca aagcaactct gtgtgttacg ttaaagacgg
     4921 acaagccatt ggtatagggg ctggacaaca aagtcgtatt cattgcacac gtctggcagg
     4981 caataaagca gacgaatggt ggttgcgtca gtgtcctaag gtcatgaacc taccttttaa
     5041 agacggaata cgccgtgccg accgcgacaa ctccatcaat gtatacatat ctgacgagta
     5101 cgaagacctt ttacaggaag gaacatggca gctcttcttt accgagaagc ctgaaccatt
     5161 aaccttaacc gaacgtaagg cgtggatagc acagaacaag caagtggctt tagggtcaga
     5221 tgcattcttc ccctttggcg acaatataga gcgtgcacac aagagtggtg ttgaatatat
     5281 tgcccaagct ggaggcagca tacgcgacga ccatgttata gaaacatgta acaagtatgg
     5341 catagcaatg gcatttacag gtgtgcgttt gttccatcat taataaaata taagccagat
     5401 tgagtaaata cataaagtat gagcgatata gacgaaatta tagaaaacgg aatggttttc
     5461 agaggagcac ctaaagccaa agccgatgat ggtaaaataa aaactaaagc aaaaaaaaag
     5521 aaatacataa caggtgctca tggttctgga agtgcgaagc agaaagcaaa gtatagacaa
     5581 caaagggcta accgacataa gtaagtatta caaatatctg tacaataagc attaatataa
     5641 ggctatagag atttgcttta tgtcatattt ttgttagatt aaacgtaatt aacagaaata
     5701 gtttgatgat ataaaagatt atcgtttatc tttgcacata ttatttttaa agcaataaaa
     5761 agatatgaag aaagtattca ttttaatggc agtttgcgcc acaatggttg catgccagca
     5821 gaagggaaaa caaaatgctg atgctaaagc aggcgataca acaaaggttg aagctactga
     5881 ctctatgcgt tatgcaggcg aagttcctgc agccgatggt ccaggtatac gctacgaaat
     5941 tgcattggca aacgacagca caaacggttt cagcataaag gaaacctatc taaaagctga
     6001 aaagggtaag gataaggtgc tcaactatac aggtaaagca gagaagatag agaaagacgt
     6061 taaaggacag aagaaagttg gctacaagtt tacaacaggt aaagatgatg ctctctactt
     6121 cttgcaagct aacgactcta cacttcgtat ggtgaacgac cagttggaag aagccgcaac
     6181 aaaagacctt aactatgact taaagttagt taagtaatac ggataagaaa tttataaatg
     6241 ggagataatg cccgaaagga acattgtctc ctatttttgt ttatatatac cacaagtgca
     6301 aaaagaaatc agtagaaaag aagtggaaaa attataagca gcgtctactg tctacacgct
     6361 aatcaaatgg aatgtcgctg atgtttataa aagcccgtca aatgtagtta tttttctttt
     6421 agatatctgt tgcgttcgct ttagatatct gttattttca aattaaatat cacaacaaac
     6481 tacaactttt attattttat agtctaatac tcgaaatata tttatcagct gagtaatatg
     6541 aaatctttta ttctgcattg ttttaatttg aaaatcatta taagtgtttg ataaacacta
     6601 tgttgttcga tattatgtta cataagagag caattcatta caataatctt ccttcctaaa
     6661 gaatcctcca cttcttttct actgagccac aaaaaagcca accaaagcta ccgagaacac
     6721 aaagaaaagc attacatttg tgagcaatta aaataaaaga agagaatgaa gcagcaaatt
     6781 gtttttacac ataaattcga gcaaagtctt tcagattcca tagcaaaatg taatccagat
     6841 aagatatttg ttcttgccga cgatacaaca atcggaatgt gctataatag gataaaacac
     6901 ttcgaatgtc ttaaaaaagc acaacccata actattccaa gtgcagatgt aaacaaaaac
     6961 ttatcgtcgc tctcctgtgt gtggaaggtt ttgcaaactg caaaggctac caggcattca
     7021 atgcttataa atcttggtgg tggaatggta accgaccttg gtggctttgc agcagctaca
     7081 ttcaagcgtg gcattaactt cgtaaacgta ccaaccacat tgttggctat ggtagatgcg
     7141 agtgtaggag gcaaaactgg tataaacttt gatggattga aaaacgaaat aggagcattc
     7201 gctttccctc aaactgttat tatcgataca caatggttag gaacgctcga ccgtgaaaat
     7261 ctgttgagcg gttatgccga aatgctgaaa cacgggttga tagccgaaaa gggagcattg
     7321 gcaacgctat tggctttcga caccgatacg ttcaacttgc gacagctcgc cgaaatgctg
     7381 aaagagagtg tcgaaataaa agaaaagata gtggaacaag acccccacga gaagcacata
     7441 aggaaggctt tgaacttcgg acatacgttt gggcatagct ttgaagcgtg ggcaatgacg
     7501 cgaaaaccta tccttcacgg ctatgcagtg gcgtacggaa ttgtctgcga gctttatctt
     7561 tcggttgtaa agcaaggttt tccgactgat ataatgcgga aaacggttaa ttttatcaaa
     7621 gccaattatg gagaatttgc catttcctgc aacgactacg atgcgttaat cgaccttatg
     7681 aagcacgata agaagaatgt gaacagcacg attaacttta ctttattgca agatttgggc
     7741 agggtttcca tcaatcagac agcgacagaa gacgagataa aagaagcctt agacttttta
     7801 agagaagggt agggctgggc tttggaggtt ggattgtagg ttgcttgcaa cgcttttgcc
     7861 caagtggggt tattccatat cggtgggttg gtctaccatc tgcaaggctt ttgcacgggc
     7921 aatcttacct gtttcggtgg ttggaagttg gtctgtgtgc tgataatgtg caggttgcca
     7981 gtatcgtggc aatgctttca cacaggcggc acgcacttct tccaagtcgt tagtttcggt
     8041 caggagtact atttcttcac caaacttctt gtttttacgc ttcgttatca ggaatggaac
     8101 agcgagataa ggacgcaatg cctgttccac ttcctccatt tgcaccttta ttccgcccgt
     8161 attgatggcg ttgtctttgc gtcctaatat acggaactcg gctcgtcctg cttctgtcag
     8221 gcgcaattcg gctatgtcgt tggtctccaa acgttgagaa cagacggctg gcgcattaat
     8281 tacgagacag ccatcgtcgt tcaacgacac ctccacgccg tcgaatggcg tgtaccaatc
     8341 gctgctttcg cttccgttta agcgacgaag agcaatgtgc gatagtgttt ccgtcatacc
     8401 gtaagtgctc cataccgcat tagggaagtc ttttagctgt gcagaaagtt cattgtcaat
     8461 gcttcctcca cctattatta aatggcgaat gcgctgcaat cgcttgcgtt ccttgctgtt
     8521 ttgcagtgtg ttgaatacct gcaaaggtac cattgctgca aaggtaatag gctcatcggg
     8581 gtttgaaagc tgagcaagcg aagcatcgga aagcgggttc cctgatggtt tcacgttcag
     8641 caggcgcagc tttcgctcta tgctgcgtac tacaaccatc ttcccagcaa tgtaatcgag
     8701 tggcatacac agtaaggctg tatcgttggg gcgtaacttg agaaagtcgc aagtgatgcg
     8761 tgcagagttc agcatacgtg ctttttcgac acgcaacggc tttggctgcc ctgtcgaacc
     8821 actcgtatga acaagcaaag tggggtcttc gctgtgccat tcgctaagaa attgctctaa
     8881 agtcattgct gttttcttgt tttaaagtcc cactgtcaag cccttctttc ttatctgttt
     8941 atgttcaatt atgcagttgt tgcattatcc aaagcttgtc gccgataact tttaaaggca
     9001 tttctatgtt gtcggcgaac agttgtcccg tgcctaaacc ttgagcgtgg cgtatgtttg
     9061 tgccgtaaat gcttgctgtc aattgcgcta tggcgttaag accgacgttg ctttcgaggg
     9121 cagaagtaat ccaagatccg atgtttcttt cacgagcgag ttgtatccac tcctccgttc
     9181 cagccattcc gccgtgcaaa ctgggtttca aaacaatgta ttgaggacgg attgtgtcta
     9241 ataattcaat ctttttctgc ctttcattca cgccaatcag ttcttcgtcg agtcctattg
     9301 gtaaaggtgt tgcagtgcaa aggcgtgcca tttccgtcca ttggttctgc tttatgggtt
     9361 gctcaatgga atgaatgtcg tattgaacca acgcttccat tcgcgaaagt gcctcttcgg
     9421 gtgtgaaacc accatttgcg tccaatctca actcgacgtc gttgcggctg aaagtggaac
     9481 gaatgtggcg tatgagttgc agttctcggt cgaaatcaat cgctccaatc tttatcttta
     9541 tgcagcggaa acctgccttt agcttggctt ccaaacgttc aaacatttcc tcgaacgttc
     9601 ccatccatac caaaccattg attggaatgc cttcttcgcc acgtccgaaa ggtgtgtcga
     9661 agaagtttaa actgccttta gcgttgaact gtgccactgc tgtttcaagt ccgaagagca
     9721 tagatggata ggcgcgcatt gcttcataat cgattacccc tgtacgttcg tactcatcgc
     9781 agaacgttct cagcttgcgt tcgtattcgt ttggtggcat cgcatcgcaa gaaaggtcgg
     9841 gcagcgtggc acattcgccc actccgacca catcgggttg ctcgtcggag gtaagtttca
     9901 agtagaaact aagacgtgta ttatatactc cacgcgacgt tcctgcaggc tgaagaaagt
     9961 gtaacagctt ggaagtaatc gttattttgc gcatcgctgc ttatggaaat tgagggtatt
    10021 tgtcgaagtc tggcttgcgt ttctctaaga aagcacgtcc tccttcttgc gcttcgtcca
    10081 ttgtatagta aagcattgtg gcatcgccag caagttcctg aatgcccgcc tgaccgtcta
    10141 actcggcatt cagtcctgct tttatcatac gcaaagccaa tggcgagcgt tccatcatgg
    10201 tttctgccca ctccacgcac ttgtcttcga gcttatcgaa aggtacaacc ttgtttacca
    10261 accccatacg ttcagcctca gccgcagagt attgacggca caagaaccat atttcgcgtg
    10321 ccttcttctg tcctactatg cgtgcaagat acgatgctcc gaagcctgca tcgaacgaac
    10381 ctaccttcgg accagtctgc ccaaagattg cattttctga tgcaatgctt aggtcgcaca
    10441 taacgtggag cacgtgtccg ccaccgattg cgaagccgtt taccatagca atgacaggct
    10501 tgggtaagcg gcggatttgc atttgtacat ctaacacatt caaacggggt actccgtcgc
    10561 caccgacata gccgccacga cctttcacat tcatatcgcc acctgcgcaa aaggctttgt
    10621 cgcctgcacc tgtaagtagc actacacgaa tgtttaaagc ctcacgacag tacgaaaacg
    10681 cctgtgaaat ctcccaaacc gttagcggtg tgaacgcatt tcgatagcgt gggcgattga
    10741 ttgttatctt tgctatgtgg ttgtattcct caaaaaggat ttccttaaag tcgaaacctt
    10801 cgatggtttt ccattctctg ttagccatat tatgattgtt tttatttatt gtttcttttc
    10861 taattgcttg taaaatgtgc tccacgcctt ggcatctttt tcgggatcgg tgaacacttc
    10921 caatagtacg gaactttttc tgatgttgag aaacgctgcc aaacagtttt ccaactcttc
    10981 cgaattggtt gccgaaaggt agcctatgtt atgcgtttgg catactcctt tggcggtaac
    11041 gcttacgcca gcacccatta tcgcagctcg gtgtgccgat ttttccaatc ctgacagttg
    11101 ctgaaagata ccgccaccac tgttgttgag cagcaagatg gaaaggttgt cgcccaaatt
    11161 gctgttccac aaggcgtttt ggtcgtagaa aaagctcaag tcgcctatag cgcagaacac
    11221 acgtttgtct ttgtttgccg ctgccatacc tactgcagtg gagagcgttc cctctattcc
    11281 gtttacccca cggtttacaa aaatgtagtc ggacgagaag aaattgccca agcgaactgc
    11341 cgaactgttc ccgtaaacca atgctttggc atcgttgttt tgctgcaata gcgtgtgaaa
    11401 acgctttact gccaacatct gcgaataagt tggaacgtac gattgcgcag tggctgcggc
    11461 attgttcaaa gccttttgcc aaccgtgata gaactttgaa gttgcaaaat cttccaaacc
    11521 gcttgccaac gccttgatga aagcatcgct ctggcactga actacggcgg taaggttggt
    11581 gaatgtgtcg cgaatatcgc cacgtgggtc tatcaaaata gaatctttcg gggtgcaact
    11641 ccgcaagaac tgtttgcact gcttgctcac caacgtgccg cccatatata taataaggtc
    11701 tgggcgcaat gcttccgtgt cttctgcaat tgttattgcc gcatcgacaa gctgcggtgc
    11761 ggtgtcagta acatcggaaa gcttgtcttg tatcaccacg atgtgttggc gcaaccttac
    11821 taattccgcc ttcacttctg tcatatcagc ccacgcttcc tgcccgatga taagcaaagg
    11881 acgttgcgcc tgtcgcacca tcgttacaac atcggctacg gcagcattgt cgttgcagac
    11941 agatgtagca gaaatatgtc gttctgtggg caaggttgcc acatcgtaat cgaataacgg
    12001 ctcgcttatt ggtacgttga tatgtactgg ggcatacgca aatcgcttgc attcaatgag
    12061 aacttcgttt accaaacggt tgcaatacca atgttcttcc ttcgttttgg gttcgataag
    12121 gtggacgctc ttgcgcacaa acggagcgag agcgttggct tgtggcatgg tttgtccgtc
    12181 cgattgccct atccattgct ggggacggtc ggctgaaacc actatcaaag gtaggttttg
    12241 ataatacgct tctgtcacgg caggtgcgac gttcagcagt gccgaccctg acgtaacgca
    12301 aacaacaacg ggcgaatggg tacttatagc aacgcctaaa gcaaagaatg ctgccgaccg
    12361 ttcatcggtt acaggatagc attttatatc tttgcattca caaagattat gcacaagtgg
    12421 cgagtttctc gagccagggc acaccacagc ctgcgttatg ccgtgctgaa cgagcaacgc
    12481 cgtcaggata tttacgttct ctttgttact gaacatcttt attattgcgt tttaacgaag
    12541 tagttgtcgc attgtcgata gcttggcttc ggtttctttc cattcgcttt cttccgtgct
    12601 ttctttcagt attccgccac cggcatacag gttgcagaca cctgtttgca tctgcataca
    12661 gcgcaacgac acataaatgt gcgtgttgcc ttgtaggttt agcggtcctg caaaaccact
    12721 gtaataaagt cttttattcg attcgttggc aagaatgaat gcctttgtct cgtctttggg
    12781 cattccgcaa accgcaggtg ttgggtgaag gtcggacaga agttgtccta tggctgcatc
    12841 ggggcgtagc ttgaaactga agtcggtgcg cagatgcacc aagtcggcag cctgcgtggt
    12901 gtatgcccct tcttccttta tctcatcggc acagcgttcc aagcaccttt ttatatagag
    12961 agaaacgtac tgttgctctg ccttgttctt tgccgaccat tctattccgt tctcattgta
    13021 aggcattgtg cctgccaaag ccattgttcg ccattccgtg ccattgccat cgagcagtat
    13081 ttcgggcgtt gccattaacc aaatgcccga ctgtggggtg gaaaagaggg ctacaaactg
    13141 gcgtggatac ttcttgcaag cctgccaaaa cacctcttcg ggttgtaaat cgtggggaat
    13201 ttgctcctgc acacaacgtg agagcactat tttagcaaac ttgttgtttg ccaattcttt
    13261 atgaaaggca gcgaaatctc tgtgatattt cgctctgtct gcttcttttt cgcttgcttc
    13321 ttgcttttct tttgctaaag actgcacctc ttttacgggc atcatacgca cttcgtcggg
    13381 ctgcaaaagc agtatgggac aatcggctga cggactgaac ggtgcaatta caaagccttc
    13441 cttgccgtct aattcggtaa gcgacgacaa ctctgaaggt gcggaatgct gcaccaacat
    13501 tgtacattct tcggcaaaag gcaagcggta gacagcaaac gaacgcatga ctaaaactcc
    13561 tataactaca gttttctgtt tgaatggacg atatagttcg ttacttgtac cgaagaaata
    13621 agttctcctt catcatcttt tacgtctata tgccatacat gcagcttgta gccttggtgc
    13681 aaaatgcgtg cataagccgt aaccatacct ccgtaaggca ctgcctttac gtggtttccg
    13741 cttacattta tgcccaaagc catcttacca tcgcaaagca ccatggagcc taaacctgcc
    13801 acattctccg ccaatgccaa tgttgcacca ccggaaagga aaccaaacgt ttgcctgttt
    13861 ctgtcgccga cagccatctt tgccatcaac gtgtcgggtt ccggggttga tataaaatgc
    13921 attcccaagg tgcggctcaa cccctcttcg ttctctaaaa tagcactgta cttctctacg
    13981 ttcattcttt ttattctatc taatagctat aattaacaac aaatattatt gagttgattg
    14041 tagttctact actgcaaagt tagcaataaa ctatcagata aagaagccaa agctattaat
    14101 ttgtgttatt ggttagacca cactacaatc acatttcttt cacataagcg gataatgggt
    14161 gttactttgt attccctttt ttattctttc aatattttta cacttgcaga ctgacaacaa
    14221 agaggactaa atatagtgat tgctaatcat ggatttcaac ctacataaca aacaaaatcc
    14281 tcctcgttcg aagtatatcg aacgaggagg aactttatct atacgacttt atattgttta
    14341 cttcactacg attttcttgc cgttgtgaat atagatacca cgtgtcggat tcagcactct
    14401 acgcccttgc aggtcgtagt agtagccgtc accagcattt tctgtagtag tttcgcttat
    14461 gttttcaatg gcgtttggct gctggcgata gccgaaaaga atggtgccgt cggcattcac
    14521 ctcgatgcct tgtatggcat tgttcaccgt aagaccatcg tagaacgtta gtttatcgat
    14581 gttcttcttt tctactccga acagattttc tttgtgagca ctatagttca gctgttcgtc
    14641 atcggcagga ataatgtatg cacgcatctt gctatcaacc gtattcacgc tattagtctc
    14701 ccaagttccc ttggtgtagg caaagtggct aagcattaag ccatcgccga aagtaaacgt
    14761 ttcgtagccg ttagctcttc tttctttata tgctttggga taccacgtgt ccgaagttct
    14821 gttctcaaga ataaagtatt ccgcacgatt acgtgtagaa cgtactattg ctgccaactc
    14881 gccgtttctg tttgaaacag gatcgagctt aactgtctga ggagaagtca gttcttttat
    14941 cttcaaccaa cctaaataag agcgttcgta agctgtataa ccgataggtg cattggcgtt
    15001 gttcacataa ggaccagcgt ccataataga ccaataacca aacggattgc gagacaaagt
    15061 tacagaaggg tcggtgttat agaagtcggg caagcctaac gcatggccga actcgtggca
    15121 gaaaacgccc attcccataa gcgttccata gtagtttagc tcatttccaa cgaagtatga
    15181 attgaaaggt atgccttcta tggtttcgtt aatgtcttgc tcttgcggcc agatatagtt
    15241 ttcatagcct ggtttattgg ggtcttcggt agcctgtccg cgacctgcat agaacaagca
    15301 aataagttct acatgccctg tctttgcgtt cttaaacttg tcgaaactta tgttttgtgc
    15361 tttagcttcc ttcacaacgt cgcgcactaa ctctgctgtt ttctcatctc taccatagta
    15421 tgcatagctg tgatttacct ttatcggacc tattacttca aatgttggca caaacatacc
    15481 acggctttgc gactcgaaaa agtcttttac agaacctacg caacctggtt cgtcgtgata
    15541 acctgcctcg ttataatagc gcatcatctt ctccggtgta gttgtagaaa gaaagtcttt
    15601 atccttaaat tctaccatta caacgggcac aagtggtgtt cctatactgt tgatgccgcc
    15661 cattcccgac ctgttgtact cgcctaagcc atcggctgta gaggcgctta tcgccttaag
    15721 cggtgcatta tgcgctgtac gtttagctac actttttagc aaatgcatat tcttctcggt
    15781 cttgtttgcg tccaagaaag ccttttcttc agctgtccga tcgcctgctt cgtgtgctat
    15841 taaagcagat ggttgtagtt ttccatcgcg tataacggca taataaaaac tattgttagc
    15901 gccttttgac aagattttcc catcgagcgt tgtataataa accgtacgac cgcctgcgcc
    15961 tctaaccatt atcttgatgc tggtgctgtc gctttgtttc actgtccaaa cctttggcat
    16021 tggtccaaca gcaagtgtcg ggagcgtaat agctgccgac aaaagcattg aaattaagat
    16081 ttttttcata tttctttatt gtagatatta cctatattta ataaatgggt ctgcaaatat
    16141 aactaaatcc tatataaaat cccttacaat gttccaatct tttttgtttt tttaagaata
    16201 aacgtttcac gttaaatagg caaattatat gttcaaacgt ttatagaact acgttgtttt
    16261 ctacgagtat aataaaaatg aagagcctct gaaagttttt tgtccagctt tcagaggcac
    16321 ttcaggtaaa tatcatcggg cttttttcat tctcacaagc tcaattgctt ctttcccact
    16381 gatatgttcg atggtgaatt caatcatgac aaggtgtgag aaatctttct ttatctcgtg
    16441 tctgagccct tcttcatcgt cgggattgta ccgcctgccc aatttgcaga gggcttccat
    16501 cttctccgtt tcatcttcta ttaagcggac ttttccgaag catatgacac ttcgaaaata
    16561 ggtagtgaac tctttgggct tcacttcgtt tcgatcgatt actgtaaacg aagccttatt
    16621 actattgtga atagcgtcca gtttatgtcc ttttaatgca gaatggaagt atagtttgcg
    16681 tcccacaagt acaggagtga tgggcacacc atagggatag ccgtcatcgc caagcaaaga
    16741 aagcacaccg gaggttgctt tttccaatat ttccgtgcat tccgtttctg ttaattcttg
    16801 gcgtttgcgc cgcatagttc taaattctgt cataataaaa acgttaatat tttattgcac
    16861 gattaacgct ttctccaact gttcgggctg ttcggggtag agatgtattt tggtttgctg
    16921 tttcgtagtg atggttaaaa cagggtaaaa caactttttc cgaatgctta cagttgctat
    16981 ttcggagagc ggcagcgtgc gcgtcttcac ttcgttcgtt gttttgtacg tcagcaagtt
    17041 gccttctatc tttatcgtca tgcggtaata gtaggcgata aagattgcta ttgtacctaa
    17101 aaaccaaaag acagcgaaga aatcgaagtc gtttgaacga aaaaggtagt aacaaagcat
    17161 tgttgtaaaa agataaccag caattaaagc caatgccatt gtgattttaa agtttctgct
    17221 tgtttggtat ttcatagatt ttttatttgc ttttgcaaag gtaatgaaaa gttcgttgtt
    17281 tctcaaaagt atagttaaaa atagctaaca aaagaggaat ggtttaacat ttaaaaagca
    17341 gcaaaataga accgtgaaac attaagataa gggttgggaa acttaaaaaa cagttttgat
    17401 ttttcaaaag tggcactttt gtcgaccaaa agctatgctt ttacatagaa atagtggctc
    17461 ttttgcaagg cgaaagcgta ggttttgcac agcaaaaatt atcttttctg ttaccttttt
    17521 agttccgttt gtatggtaaa cgctgcgctt agattgcaca gtgctaccca ctaagcgatg
    17581 aacttgttga tgttcagtgt gcttagcgtt gcacgcaaaa attgggctta tttgaaaacg
    17641 gttttatctt tgtgcagaaa actgcccttc ttagcgtgtt tcacgatttt tggtttaact
    17701 tttaaggtat ttctcttaac tttattttac gctattcttg tgcagcaatg caaacgtaac
    17761 ccatatataa aggtataaaa aaggcaaaaa taacaaggaa ttgcaaataa tttattaaat
    17821 ttgcaaatca taaagattat aattcgatta atagagaaaa tgaatgtttt agaattatca
    17881 gaacaagaga ttgtacgtcg tcagagtttg caggaactac gcaatatggg catcaatccc
    17941 tatccggcag cagagtttcc aaccaatgct tactctacag atataaagaa agaatttaaa
    18001 gaagacgaga aacgcgaagt cgtaattgca ggtcgcctta tgggaaagcg tgtaatgggc
    18061 aaggcgtctt ttgcagaaat acaagacagc aaaggcagaa tacaggtcta cattacccgc
    18121 gatgaccttt gtccaggcga gaacaaggat ctttacaaca ttgtttttaa aaagttattg
    18181 gatatcggcg atatcattgg aattaaaggt tttgtgttta aaacacagat gggcgagata
    18241 tctatacacg ccgaaaaact caccgtactg tcgaaaagcc tgaagccact gcccgttgtg
    18301 aagtataaag acggtgtggc ttacgacaag ttcgacgacc cagagcttcg ctatcgccgc
    18361 agatacgtgg acttggtggt gaacgatggc gtgaaggaaa cgttcaaaaa gcgtgccacg
    18421 gtgttgagaa ctatgcgccg tttcttcgac gatgcaggtt acactgaagt ggaaacccca
    18481 atattgcaga ccattgcggg tggtgcaagt gcccgtcctt tcatcacaca cttcaatgcg
    18541 ctgaacaccg aaatgtatat gcgcatcgct acagaacttt atctgaagcg actgattgta
    18601 ggcggtttcg aaggtgttta tgagattggg aagaacttcc gcaacgaagg tatggaccgt
    18661 ttccacaacc cagagtttac ttgtatggaa ctttacgtgc agtacaagga ctataactgg
    18721 atgatgagct ttaccgaaaa gctaatagaa aagatttgta cagaggtgaa cggtaagcct
    18781 gaaatacaag tgggcgacaa ccttatcagc ttcaaggcac cattccgccg ccttccaata
    18841 ctcgatgcta ttaaggaaaa gactggtttc gaccttgatg gtaagacaga agaagaaatt
    18901 cgtaacattg ctgtgaacga gctaaagatt gaaggtatcg ataatagctt tggtaaaggt
    18961 aagctaatag acgaaatatt tggtgagttc tgcgagagta ctttcataca gccgacattc
    19021 attatcgact atccggtgga gatgtcgcca ctctcaaaga tgcatcgttc taagccagga
    19081 cttaccgaac gttttgaatt gtttgcgaat ggtaaggaac ttgccaacgc ttactcggaa
    19141 ttgaacgacc ctatcgacca ggaagagcgc ttcaaggagc aaatgcgatt ggcagacaac
    19201 ggcgacgacg aagcaatggt tatcgaccaa gacttcctgc gtgccctgca atatggcatg
    19261 ccgccaacat cgggtatcgg catcggcatc gaccgtttgg taatgttgat gacaggacag
    19321 gagtacattc aagaggttct gctcttccca cagatgaagc cggaagccaa agttccgcaa
    19381 agcagcataa aggaatgggc agagattggt gtcccagaag agtgggttta cgtgctgcgc
    19441 aaatgcggtt tcaacctcat tcagaatata aaagaggaga aagcgcaagg cttgcaacag
    19501 aaacttggcg agataaacaa gaaatacaag ttgggatacg acaagccatc ggttgacgaa
    19561 attcagcgtt ggattgacaa agcacaatga caacataaag ggaaggcgtg cccttctctc
    19621 ttgaatacga catgtacgac gtaggaaaca tagcaatcat cggaagcgga agctgggcta
    19681 cagccatcgc aaagattgtg gtggaacaca cgcaccacat aggttggtac tttcgacgcg
    19741 acgagacaat agagcaattt cgcaagttgg ggcacaatcc cacctatctg acaagtgctc
    19801 atttcgacac caacgaaatt cgtttgtcgt cagacatcaa tcgtttggtg caagattacg
    19861 atacgcttat cttcgtaacg ccatcgcctt acctgaaagg aatactgaag aaagtaaagc
    19921 acaagttgca cgataagttc atcgtaacag ccattaaagg tattgtaccc gacgagaact
    19981 tggtttgctc ggagtacttc cgcaaggtta tgaaggtgcc agaagaaaac ttggcggtaa
    20041 taggaggacc gtcgcatgcc gaagaagtgg ctatggaacg cctgacgtat cttaccgtag
    20101 gctgcaccga cacggagaaa gcgcaggcgc tgaccgaagt attggtttcc aattacgtta
    20161 aaacgaaagt gtcgcacgat gttcttggca tagaatatgc ttcggttctg aagaacgttt
    20221 atgccatagc ctcgggcatt tgctcgggtt tgaagtatgg agacaacttt caagcggtaa
    20281 ttatttcgaa tgcaatgcaa gagatggaac ggctgcttac gagcataaat cctataaaac
    20341 gcaacatgat agacagcgtt tatcttggcg accagctcgt tacgggatat agcaacttca
    20401 gccgtaaccg cactttcggc atgatgatag gaaaaggata cagcgttaaa tcggcacaaa
    20461 tggaaatgga aatgattgcc gaaggctatt tcggaacgaa gtgcatgaag gaaatcaacc
    20521 gccatctgca cgtgaacatg cctatcctcg atgcagttta caatatactg tacgaaggta
    20581 ttagccccaa aatagagatt aaattattaa cagattcttt cagataacat acaaatggag
    20641 aatattaaat tagacatttc aaaagcagct caggtgctga acccgggcac aatggaatcg
    20701 tatgcgccac aggtggcagc agcacaagag gctttagaaa aaggaacttg cctcggtaac
    20761 gacttcttag gttggttaca cctgcctaca aacatcacgg aagagtttat aaacgagatt
    20821 aacagcgttg ccggcaccct gcgcgaaaag tgcgacttcg tagtcgttgc aggtattggc
    20881 ggatcttatt taggggcacg tgccatcatt gaagccttga gcaatagctt tgcatggctc
    20941 ttgaacgaca agaagaaccc tacaatcctt tacgctggca acaacatcag cgaagattat
    21001 ctgtacgaac tcaccgagtt cctgaaggat aagcgtttcg gtgtcatcaa catttccaag
    21061 tctggaacaa ccacggagac tgcccttgct ttccgtttgc tgaagaaaca atgcgaaaat
    21121 cagcgtggca aggaggaagc aaaacacgtt atcgttgcca ttaccgacgc tgtaaagggt
    21181 gcagcacgta cggcagcaac acgcgaaggt tacaagactt tcgttattcc agacaacgtt
    21241 ggcggtcgtt tctctgtgct tacacctgtt ggcttgttgc ctatcgcagt ggcaggcttc
    21301 gacattcagc agcttgtaaa gggcgcacaa gacatggaaa aggctacggg cacagatgtt
    21361 ccgttcgctc agaacattgc agcacgctat gctgccattc gtcaggcact ttattcagaa
    21421 gctggaaaga agatagaaat aatggcaaac ttccagccaa agctccattt tatggcagaa
    21481 tggtggaagc aactctacgg agaaagcgaa ggaaaggagc aaaaaggcat cttcccggca
    21541 gcgtgcgact ttaccaccga ccttcattcc atgggacaat ggatacagga aggagaacgc
    21601 tcaatatttg aaacggtact ctctatcgaa gaacctaaca ggaaattgct gttcccacac
    21661 gacgatgaaa accttgacgg actgaatttc ctcgaaggta agcgcgtgga cgaagtaaac
    21721 aaaatggctg aattaggcac acgactggca cacgttgatg gcggtgttcc aaacattcgc
    21781 atcagcattc caaaactaaa cgaatactat atcggacagc ttatctactt cttcgagaag
    21841 gcttgcggca tcagcggctt ggttcaacag gtaaatccgt tcaaccagcc gggtgtagag
    21901 gcatacaaaa agaatatgtt tgccctgctc gacaaaccgg gttacgagga agaaagcaaa
    21961 gctatcagaa aacgattata aagataaaag aagcccagtc cattgtttaa atgggttggg
    22021 ctttttagtt ttacacgtaa gaatgtttca ggaagcaatc agaaaataca acaaacaagc
    22081 tgcacaaccc tttgcgccga aggttgttct cttcgatatg gacggcgtat tatacgactc
    22141 tatgcccaac cacgcaaagg cctggcaaag ggcaatggct gaatttggaa tccatttcac
    22201 tgccgaagac gcatacgcaa cagagggtgc aagaggtgta gacactgtcc ggaggtatgc
    22261 aaaggagcag ttaggcaagg tactgaccga acaggaagcg gaagaaatgt accaactaaa
    22321 ggcgtgctac ttccaagaaa tgcctacaac agacatcttc gatggtgtga aagacttaat
    22381 gcagaagata caaaacaacg gcttaaagat aggcattgta acaggaagcg gacagcgaca
    22441 gcttattaac agattacttt ctgatttcaa agactttatc aacgagacac aaataaccac
    22501 cgctttcgat gtaaaacgtg gcaaaccgaa ccccgaccct tacctgatgg gcttgaaaaa
    22561 ggcaggcaat tttgcaccgc acgaaggcat cgtcgtagag aatgccccct tgggagtgcg
    22621 tgcaggtgta acagcagggt gcttcacggt tgccatcaac agcggccccc tacccgactc
    22681 agcccttctc aacgaaggtg cagatgtcct tttcgaaact attcgtgcat tttccgacag
    22741 ctgggagcag ctgacagcca gtgtggcaca atcattaaaa agatagaaga aaaggcagat
    22801 aacaggactg gatttccgac atcaaagcaa tcgataatta cgttgaagaa gcatacagtg
    22861 ccaccttgtc caaacaagaa ggcactgtta tctttctgct ccaccccacc cgtaatctta
    22921 ttatccatac agaaaaaggc tataaagata caaaacgttg ccttatctcc atcaatgaat
    22981 gattaaaaaa gcgcaaacca acactcatca cgagcattgg ttcaccttta ttattatgga
    23041 ttattcagtc taaatataat tatagaggta cgttaaagta cctttccacg ccaggttaca
    23101 ccgacgttga actgcgacat cttgtcttgt actacccctt cggggttcgc attcttgcca
    23161 aatgcgtagc tgtaataacc gtgtattctg acgttcttgt ctttaagtgg gtagtattcc
    23221 acaccagccc ctacacgagt gagttctgtt ccatcatgca aggcaacgtc ggcttcagtt
    23281 cctgcgtggt tcacttcgta gcttgccttt gcgaaaacat tcagcttttc ggtaggttga
    23341 tacgacagct gaccaataac agaacagtct ttaccaatga aaccttgtcc ggaagcggca
    23401 cgattccaat aatccaactc taattgaagg ttgttggtaa agtgaaattt attgcctaac
    23461 gaaatgtagt tgatgaactt atgaggagca tattccgaca tatttaccga ccaaaaagtt
    23521 tcccatattc cgtgtcgtcc attccacaat acattatagg catacatttc ggctgcctta
    23581 cctgccttgt tttcatagac tttttgatat gggctttggc aaatctgtgc cgagaataca
    23641 tcgtttccac tattggtagc cagttcgccc actactcccc attggtaaca agggaagtta
    23701 tagcagaatt cagataagaa ataacagtcg atgggtgctg gcaacaactc gtagcccgcc
    23761 accaatacaa tgtattttcc tgcaataata gctacatttt tattaggttt atattttaag
    23821 tagagccaat cggtggagtt aaagaagttg tagtctttat taataccatt caatcggtta
    23881 cggaaagcat acgagaactt tggagaaatg tcgcctttca gaatgatatt cactatatat
    23941 cctttaaagc cgctttcgtt cttaatgtgc tttccatcta tatct
//
