LOCUS       c00006_NZ_UGTL..       23984 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_UGTL01000001.1 Prevotella disiens strain NCTC11157, whole genome
            shotgun sequence.
ACCESSION   NZ_UGTL01000001
VERSION     NZ_UGTL01000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:24:27
            Original ID  :: NZ_UGTL01000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 752386
            Orig. end    :: 776370
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23984
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[762386:766370]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13984
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..23984
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23984
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_fatty_acids"
                     /region_number="3"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             811..1104
                     /locus_tag="ctg6_645"
                     /transl_table=11
                     /translation="MGKALKKFIVEFERKIPQYAHLSVDYERVSAILRKRNIHLQSKSL
                     RKLWGYVLTKDKPSKKTLDRLALFAGFQNWHDLQEALHGETDGQINYEDNED"
     CDS             complement(1416..1904)
                     /locus_tag="ctg6_646"
                     /transl_table=11
                     /translation="LIDYQIICRNFAALFGITAGHGRVVFHVVLERQTILINRKMDLIK
                     IAEEAFATGKKHPEFRAGDTVTVAYKIVEGNKQRIQLYRGVVIKINGEGEKKRFTVRKM
                     SGTVGVERIFPMESPNIDSIEVNKHGKVRRAKLYYLRNLTGKAARIKERRVITAKNDK"
     CDS             2177..2980
                     /locus_tag="ctg6_647"
                     /transl_table=11
                     /translation="MTKKMNLLGGIAVALSFASCASHYKLENVQRSRITIDARFDNNKD
                     AQAAAFLAPYKHQVDSIMSPIVAQSDHYMKVQRPESDLSNLLADILVWAAKDYNEQVDF
                     AVYNIGGIRAALPKGDVTVGDVNDIAPFENKICFLTLTGDKVLELFRQIAHVGGEGVSE
                     GVQIGLSQDNLLQFARLHNKEIVPTAKYRIATIDYLAQGNDKMEAFKMKTEFNSPQDAS
                     NNTRFIILNYFKAMTAQGKKINSKTEGRIAYFANEDKIPPVIILK"
     CDS             3002..3838
                     /locus_tag="ctg6_648"
                     /transl_table=11
                     /translation="MEKKILLVALCMFSMVGFAQKKQLTILHTNDTHSQIMPFNTTLAD
                     TMRAGRAGFERRISMLKEERIKDPDLLLFDSGDFCQGSPYFTMFKGDVEVGLMNQMHYD
                     AGTIGNHEFDFGLDNMTRMFKALNFPIVCANYDFADTELAKIVKPYIILNKKGLKIGVF
                     GVSPELKGLVLEANYGPLKYMNPIPCAQKCVNELKKQKCDLIICISHLGVNIEGISDEE
                     LVAGTRGIDLVLGGHSHTFLQELLYVKNLDGKEIGIDQNGKSAIFVGKMILDLKKK"
     CDS             3994..5157
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_649"
                     /sec_met_domain="Peptidase_M20 (E-value: 1.2e-32, bitscore:
                     110.3, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQELINSLSVLQSEMKEWMSALHQHPELSMEEHWTSQYIASKLE
                     EWGYDVAKGVGGTGIVASMTVGNGTKSIGLRADFDAVPIAEDNNLPYKSQNEGIAHLCG
                     HDSHSTMLLGAAKYLSEHNDFNGTVRFIFQPGEETMQGGTSMIADGLFERFPVDAVYGM
                     HNMPGLELGKFYFHENETMSAVDNWEIELIGKASHGSMPELSIDPLVCGASLVMALQTI
                     VSRNISPWSNTVVNVGAFNAGVAGNSVPQTATLQLSIRNMDSKVRQFVLDRIRFITKAQ
                     AESYNCEYKIHEGVAGTVLINTPENTRWAAQVARDTFGNDQVSEDMHPYMSSEDFAFML
                     QKKPGNYCVMGNGDTQMVHHPHYVFNQQMLSRGATYWVALVQEYLKK"
     CDS             complement(5460..5831)
                     /locus_tag="ctg6_650"
                     /transl_table=11
                     /translation="MNGFYTIGLLIVANIFMTFAWYGHLKLQQIKVISDNTPLYFVILM
                     SWGLALAEYCCQVPANRIGYVGNDGTFSLMQLKVIQEVISLVVFTIFTVVFFNGESLHW
                     NHFAAFACLILAVFLAFMK"
     CDS             5967..7013
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_651"
                     /sec_met_domain="Fe-ADH_2 (E-value: 4.3e-08, bitscore:
                     30.1, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHPIIFTAELECTLSQFIDECKPDKVFILTDDVTIEACYPIVQH
                     FYCLKNSVCITIPSSDNNKTLGSLTQVWNYLQKEKATRHSLLINLGGGMITDLGGFAAA
                     TFKRGMRFINLPTTVLAMVDASVGGKTGINFGGLKNEIGAFCDAEAVLIDTKWLKTLDK
                     ENILSGYAEMLKHGLLSERSHLTELLTFDIDDIDLKKLFALLEKSVEVKKKIVEKDPHE
                     QNIRKALNYGHTFGHAFESWAMRRNQILHGYAVAYGIVCELYLSVVLQGFPTEVMRHVV
                     NFIKAHYGVLPISCDDYLELISLMQHDKKNHGGTINFTLLQDVGKIAINQTASEEMIRE
                     ALDFLREG"
     CDS             complement(7194..7469)
                     /locus_tag="ctg6_652"
                     /transl_table=11
                     /translation="MLAYEYEKETEDGIKTTSNAFKIAPFVRWYYVHNGPFNLFLDSGL
                     GFDFGKTKTNGVKNDRHGFEIGIRPGACVDLTEGLCLCLRMGFMGY"
     CDS             complement(7791..8798)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 57; E-value: 4.3e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_653"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-16, bitscore:
                     57.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLQEFLAEWHNVSPTLTVHTSGSTGKPKPICVEKARMLNSARIT
                     CNFLGLEKGDTALLCMPLDYIAGKMMVVRSIERNLKLLSVKPSGNPLSNDSLADLNNPD
                     ESITFAAMVPLQVFNTLKNKEECERLKAIKHLIIGGGSIDTDLSNQLKDFPNAVWSTYG
                     MTETLSHIALRRLNGEEKSEWYTPFNGVKVSLNNDGCLTIAAPMVSQLPLLETNDIAEL
                     QQTASGKTKFRILGRKDNTINSGGIKIQMEEIERALRPYLIAPFAITKRPNKKFGEEIV
                     LITESNSLDSVRSICQDKLPRYWQPAFYKTVQSLPTTETGKIARAKVLEIACNS"
     CDS             complement(8824..9885)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_654"
                     /sec_met_domain="MR_MLE_C (E-value: 3.1e-27, bitscore:
                     92.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKITIISKILHFLQPAETSRGVYKTRQSFYISLTSDEEPGVVGI
                     GECVTLPDLSCDAMPEKEYENKLRAFCNDYERTGIIDYEAMRNYPSMLFGLETAVAQLG
                     SKGSLNFFDTPFGRGKEGIPINGLVWMGTFDEMFQRLETKLKQGFHCVKLKIGAINFER
                     ELDLIRHIRQSFSAKDVELRVDANGGFSPKEALSRLEALAKYDIHSIEQPIKQHQWAEM
                     AQLCANTPLPIALDEELIGVNEHDEKVELLETIRPQYIILKPSLHGGMAGTKEWIELAN
                     ERNMGSWITSALESNVGLNAIAQLTAKIYGSGITHAQGLGTGQLFADNIAMPLEIRGDQ
                     LWISQKEAHIHIV"
     CDS             complement(10001..10828)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_655"
                     /sec_met_domain="ECH_1 (E-value: 7.8e-79, bitscore: 261.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANREWKSIEGFDFKEILFEEYNHIAKITINRERYRNAFTPLTVW
                     EISQAFSYCREALDIRVVILTGAGDKAFCAGGDMNVKGKGGYVGGDGVPRLNVLDVQMQ
                     IRRLPKPVIAMVNGFAIGGGHVLHVMCDLSIASDNAIFGQTGPKVGSFDAGFGASYLAR
                     IVGQKKAREIWFMCRQYSAVEAERMGLVNKVVPFDRLEDECVAWAETMMERSPLALRMI
                     KAGLNAELDGQAGIQELAGDATMLYYTMDEAQEGGRAFLEKRKPDFDKYPQFP"
     CDS             complement(10840..12513)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_656"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.4e-09, bitscore:
                     34.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSNKDNVNILTALLIQHNITDIVVCPGSRNSALVHNFCEAEDMV
                     CYPVTDERSAAFFAVGVSLAKHKPVVVCVTSGSALLDVAPAVAEAYYQNVPLIVISADR
                     PAQWIEQGDGQTMPQANVLSPFVRKSVNLPEPKDEEEHWFCNRLVNEALIECSRMEYGP
                     VHINVPISEPLFNYDVEKLPLERKITCSQQINDSNAARKIVENIGKCDRPLIVIGQEAR
                     NRMEAVKHEINALRKRFVIVQDKLSDATEAEPQAIDALLASTDNIEALRPDLIIYMGGT
                     IVSKLLKRFLRNSNPEHSILIDPRGEIRDTFMNLTDAVQCSTIDFIKLLATETKAIKSS
                     NYYNLWQKEGQRVGNIAKNYVPTYSQMLATKLFHEKLNQYKVERQVVYGNSSAVRLGNF
                     YSSDYIFVNRGVNGIDGSLSTAVGLAAANPTVKTFCIIGDLSFFYDQNALWNNNLHKNL
                     AILLLNNSGGGIFLQLPGLEKSAHRATIMGSGLPVTAQGACQTHGIHYLSATNSKELKT
                     GLEQFFNQKDSPILLEIFTDTATDAAAWQTFNEEIKKNNK"
     CDS             complement(12530..13546)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_657"
                     /sec_met_domain="Chorismate_bind (E-value: 1.5e-53,
                     bitscore: 178.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSFAIYRLPYAKECTKMVQQTAPLEVASLQDLNGKTGFVIVPFM
                     PSAQCPILLLQPEEVVTLAVKQPETILKKEVKPTERKEYRDDYHKDFAVFHEQICNGRF
                     SKIVLSRCVEEEKSSNLQAEEIFWRACQRYPRQFVALFSTPQTGTWLMATPEILLDGNS
                     SNWKTMALAGTMPYQSDEIIWSEKNKAEQQYVAKYIRQCLEQHATDIEEQGVYTAQAAN
                     LAHLRTDFKFQLKDNTQIGTLLNTLHPTPAVCGIEKEIARKFILDNETTPRRYYSGFAG
                     ALNLNGNTHLYVSLRCMEIMETKCRLYAGGGLLTDSTEESEWQETEAKLATMRQLLE"
     CDS             complement(13565..13984)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_658"
                     /sec_met_domain="HBT (E-value: 6.2e-12, bitscore: 42.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIEKHRIALENEDGLSRTLGMRFLSTPEPDTLMAKMAVDDRNKQ
                     IFGFLSGGATLALAENVAGVGSLALCPGKVALGINVSGSHVKAMPYGGTVTAFGKLVHK
                     GKTLHVWQVDVKNDEGEIISTVSVTNYVINPKQKK"
     CDS             complement(14191..15930)
                     /locus_tag="ctg6_659"
                     /transl_table=11
                     /translation="MKRILLSALFAAATILPTFAIGPSPRIWTTKQSDGTLLKFRQHGV
                     ERVEYFTTLDGKFMVKNANGDLAYAMIQDGKLVASQYIAHEAGNRSNEEKAFLNNNDVA
                     NKLSILHTTHRHARHAPLKAIHASTDDGLGKFNTTGAGGVNSIGTPTIPVIMVEFTDAK
                     FDAKTTKEKLERFYNEVGYKDELLCKGSVKDYFTSQSRGKFVPTFEVLGPVNVNKSYKT
                     YGKRTIYDEDSDIDGLVRDAVNAATAKGYKFDNFKDKDGKVQLVCILYAGKGQATESNA
                     DPNTADLIWPCQNDINETIGNTHFNSFFVGNELDHENKLMGMGIFCHEFGHALGLPDFY
                     KTDYYTDGDDPFGFWSIMDGGAYVNDARAPIGYTAYERSYLGWLDIKELKKTEEVVLDP
                     VSNPNGTLAALVRNPENNKEYFIMENRHTDTWYPASYTYGDICTFGNGLLLTHFSYDKY
                     TWDKNVVNNDYNFKHAYVVTANNEKLSFNARREHLFGVNKKQIDIFDFWTGKSIGQPVN
                     NIVVNPDGTIKFTYSILDPAGIENVTTTQQQGDGYYYDLQGRRVTHPTHGIYIHNGKKI
                     VVK"
     CDS             16862..18592
                     /locus_tag="ctg6_660"
                     /transl_table=11
                     /translation="MNVLELSEQEIVRRQSLQELRNMGIDPYPAAEFPTNAFSTDIKSE
                     FKEDEKREVVIAGRLMGRRVMGKASFAEIQDSKGRIQVYITRDDLCPGENKDIYNVLFK
                     KLLDIGDFVGIKGYVFKTQMGEISVHAQELTLLSKSLKPLPIVKYKDGVAYDKFDDPEL
                     RYRQRYVDLVVNEGVKETFQKRATVLRTMRNFFDEAGYTEVETPTLQTIAGGASARPFI
                     THFNALNTEMYMRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRFHNPEFTCMELYVQ
                     YKDYNWMMSFTERLIEKICTAVNGKPEIQVGDKLISFKAPFRRLPILDAIKEKTGFDLN
                     DKTEEEIRNIAVNELKLEGIDASFGKGKLIDEIFGEFCEGSYIQPTFIIDYPVEMSPLT
                     KMHRSKPGLTERFELMVNGKELANAYSELNDPIDQEERFKEQMRLADNGDDEAMIIDQD
                     FLRALQYGMPPTSGIGIGIDRLVMLMTGQEYIQEVLLFPQMKPEAKIPQSSIKEWAEIG
                     VPEEWAYVLRKCGFNLIQNIKDEKAQGLQQKIGEINKKYKLGYEKPSVDEIQQWIDKAQ
                     "
     CDS             18633..19628
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_661"
                     /sec_met_domain="F420_oxidored (E-value: 1.5e-05, bitscore:
                     22.5, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 2.8e-33,
                     bitscore: 112.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDVGNIAIIGSGSWATAIAKIVVEHTHHIGWYFRRDESIEQFKR
                     LGHNPTYLTSAHFDINEIRLSSDINRLVQDYDTLIFVTPSPYLKGILKKVKHKLHDKFI
                     VAAIKGIVPDENLVCSEYFNKVCHVPEENLAVIGGPSHAEEVAMERLTYLTVGCTDQEK
                     AHALTDKLVSNYVKTKVSRDVLGIEYASVLKNVYAIASGICSGLQYGDNFQAVIISNAM
                     QEMERLLSSINPMQRSMVDSVYLGDQLVTGYSNFSRNRTFGMMIGKGYSVKSAQMEMEM
                     IAEGYFGTKCMKEINRHLHVNMPILDAVYNILYERISPQVEIKLLTDSFR"
     CDS             19641..20981
                     /locus_tag="ctg6_662"
                     /transl_table=11
                     /translation="MIKLDISKAAQVLNPGTVEAYAPQVAAAQEALEKGTCAGNDFLGW
                     LHLPSSVTEEFINEVVGVANTLREKCDYVVVAGIGGSYLGARAIIEALDNSFAWLLKEK
                     KNPTILYAGNNISEDYLYELTDFLKDKRFGVINISKSGTTTETALAFRLLKKQCENQRG
                     KNEAKGVIVAITDAEKGAARTAATREGYKTFVIPDNVGGRFSVLTPVGLLPIAVAGFDI
                     QQLIKGAQDMEEATSANAPFAQNIAARYAAIRQALYSQAGKKIEIMANFQPKLHFMAEW
                     WKQLYGESEGKEQKGIFPAACDFTTDLHSMGQWIQDGERSIFETVLSVEETNKTLLFPH
                     DDENLDGLNFLEGKRIDEVNKMAELGTRLAHVDGGVPNIRISIPKLNEYYIGQLIYFFE
                     KACGISGLVQEVNPFNQPGVEAYKKNMFALLNKPGYEEESKAIRKRL"
     CDS             21040..21771
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_663"
                     /sec_met_domain="HAD_2 (E-value: 3.9e-24, bitscore: 82.6,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQEAIAQYNEKTQQFFAPKVVLFDMDGVLYDSMPTHAKAWQKAM
                     KECGITFTAEDAYATEGARGVDTVRKYAKEQWGKEISESEAEKMYQLKAHIFQEMPKTH
                     IFDGVIDLMKKIKSSGLKIGIVTGSGQRLLIERLLSDFKDFIDESQVTTAFDVKRGKPN
                     PDPYLAGLKKAGNFAPWEGIVVENAPLGVRAGVAAKCFTIAVNSGPLSDETLINEGANI
                     LFHTIKDVANGWDELLKVTKA"
     CDS             complement(21912..22010)
                     /locus_tag="ctg6_664"
                     /transl_table=11
                     /translation="MKMMKKLASNKIIPYFVKALEMYNIGRINCPS"
     CDS             22277..22396
                     /locus_tag="ctg6_665"
                     /transl_table=11
                     /translation="MFIIYYGDFLQSKIDEFLRKSDSFDMNIEQLEGNICKCT"
     CDS             22510..22959
                     /locus_tag="ctg6_666"
                     /transl_table=11
                     /translation="MKKKIIFGLALIAMVLSFTSCNKDNDEIVETNALVHTTWSYEKSN
                     FNLQGNLKRWGSLQFQTNKDVVVTAGYEYQGEQDNFGNYHGAYNRNETSLHGIYEYKAP
                     NLTITLNAEDGQPAKTLKYIVDEKAKTILPVSNANSSDEVVYRKK"
ORIGIN
        1 aactcggcag gagctgataa cgatttaccc aataagctgt tgtgcgtact tttcgggtaa
       61 caatggaatc tgcattggta actcctccgc tgaattcttt atccttgtaa tcggcaaaga
      121 atagaattgg cttgctgttt atctccaatt ggtagtaaga ttgctgttcc actattgttg
      181 tgcaatcctc tatgtcggct tgtgaaggag gtaataatct gccaattata aatactaatg
      241 aaggtagcag aagcattccc ccgccaatga aataatatcg tttgaatttt tgaaaatgaa
      301 acatttagat gttatttttc tattggttgc aaaggtaaca atatttgcag aatttatgac
      361 gatagcattt cctttttcta tagctaaatg tgacttattc catggtcagt actctcgtga
      421 aagtactgta gtcctcccag gagagtattg taatcctctc atgagagtac tattatttct
      481 ttacttggga aactattgtg gatcaaaaga atggttattc aggtaatgca agttatgctg
      541 acgaccctta tttgggggaa tattgctcaa aaccaaatta tttcaaaact gcatttgaca
      601 cgtggctatc tacgagttaa attctcgtta tggtgtcttt ttgcttatat gaaagtaaaa
      661 tctatcatgt gaataaaaaa gagaaacgat ttaataagaa actcagaata gacaaaacta
      721 atttttagcc ccgcctaaaa ttcttttcat aaatggttct atattccaat cttttcgtaa
      781 ttttgcagtc gaaaagttga gttatagaaa atgggaaagg ctttgaaaaa atttattgtg
      841 gagtttgaac gcaaaatacc gcaatacgct catctctcgg ttgattatga aagagtttca
      901 gctatattgc gtaagcgcaa tatacacttg caatcaaaat cattgcgtaa actttggggc
      961 tacgttctta ccaaagacaa accatcaaag aagacgttag accgcttagc actctttgct
     1021 ggttttcaaa attggcacga tttgcaagaa gcactgcacg gagaaaccga tgggcagatt
     1081 aattatgagg ataatgaaga ttgattttta tttccaattg agtgtttaaa aaatattttt
     1141 gcatctttaa aatggtatct aaaacatcat taatgaacaa gggcgttagc cgtaggggcg
     1201 tgattttttc gctttgctca acaactcgat tcacgttcct aacaccctaa attttgctta
     1261 gaggaacgtg ataaatcacg cccctacgaa ggatactttt tgcttgtaac ttgctgataa
     1321 taaggaagta ggggagatat aaaactgttt ttaattaaaa aaggttcaga acaaaattgt
     1381 tccgaacctt ttttattttt ggatttgcaa gggaattact tgtcgttctt agctgtaata
     1441 actcttcttt ccttgatacg agcagcctta ccagtaaggt tacgtaagta gtagagctta
     1501 gcgcgacgta ctttaccatg cttgttcact tcgatagagt caatgtttgg agattccatt
     1561 gggaaaatac gttctacacc aacagtacct gacatcttgc gaacagtgaa acgcttcttt
     1621 tcaccttcac cattaatctt gattacaaca ccacggtaaa gctgaatacg ttgcttgtta
     1681 ccttcgacga ttttgtaagc gacagttaca gtgtctccag ctctgaattc tgggtgcttc
     1741 ttgccggttg caaatgcttc ttcagcaatt ttaattaaat ccatttttct attaattaat
     1801 attgtttgtc gttccaatac aacatggaac acgactcttc cgtgtccagc ggttataccg
     1861 aaaagcgctg caaagttacg acaaataatt tgataatcta tcaaatctta tattattata
     1921 aatgttcttt aactatattt tgtacattaa gcgcaaaaac aaatgaaatg aatagggagt
     1981 ttttctcagt ttttagtatc tttgcataag atatagctgc actcagcaat gcgtaagggc
     2041 gtgatttatc acgttcctaa ataagtaaaa gagatttttc gtaggtgtta ggaacgtgat
     2101 aaatcacgcc cctacaaaga aaaacaagtt tgcattgcgc tcgtttgcaa tatctttgat
     2161 aagaaaaaat atagatatga ctaaaaagat gaatttattg ggtggcattg ccgtagcatt
     2221 atcatttgca tcgtgtgcct ctcactacaa attagagaat gttcagcgtt caagaataac
     2281 tattgacgca cgttttgaca acaacaaaga tgcgcaagca gcagcttttc ttgctcctta
     2341 taagcatcag gtagacagca taatgagtcc gattgtggca cagtctgacc attatatgaa
     2401 ggtgcaacga cctgaaagcg acctttcaaa tttgcttgcc gacatcttag tttgggcagc
     2461 aaaagactac aatgagcagg ttgattttgc tgtttataat attggtggca ttcgtgcggc
     2521 attgcctaaa ggcgatgtta ctgtgggcga tgtgaacgat attgctccgt ttgaaaacaa
     2581 aatatgtttt cttacgctca cgggcgacaa ggttttggaa ctttttagac aaatagccca
     2641 cgttggtggc gagggagtta gcgagggagt acaaatcgga ttgtcgcaag ataatctact
     2701 gcaattcgca cgtttgcaca ataaagagat tgtccctact gccaaatatc gcattgcaac
     2761 cattgattat ttagcgcaag gaaacgacaa aatggaggcg ttcaagatga aaacagaatt
     2821 caattcgcca caagacgcat cgaataatac acgctttatc attttgaact atttcaaagc
     2881 aatgaccgca caagggaaaa agattaatag taagaccgag gggcgcatcg cttattttgc
     2941 taatgaagat aaaatccctc cagttataat tttaaaataa tctataaaac gacttgaaac
     3001 aatggaaaag aaaatattat tagtagccct ttgtatgttc agtatggtgg gtttcgcaca
     3061 aaaaaagcaa cttaccattt tgcataccaa cgatacgcac agccaaatta tgccttttaa
     3121 tacaacgctt gccgatacaa tgcgtgctgg acgtgctgga tttgaacgcc gtatctccat
     3181 gttgaaggaa gaaagaatca aagaccccga tttgttgcta tttgatagtg gtgatttctg
     3241 tcaaggttcg ccttatttta ctatgtttaa aggcgatgtt gaagtagggt taatgaacca
     3301 aatgcactac gatgcgggta cgataggcaa ccatgagttc gactttggac tcgacaatat
     3361 gacgcgaatg ttcaaggctt tgaactttcc aattgtatgt gccaactacg attttgccga
     3421 taccgaatta gcaaaaatag tgaaacccta cattatatta aataaaaaag gacttaaaat
     3481 tggtgttttc ggtgtttctc ccgaactaaa aggtttagtt ttagaagcca attatggtcc
     3541 tttaaagtat atgaatccaa ttccatgtgc gcaaaaatgt gtcaatgaat tgaagaaaca
     3601 aaaatgcgac cttattatat gtatttccca tttgggggta aacattgagg gcattagcga
     3661 tgaagaactc gtggcaggaa ctcgcggcat tgacttagta ttgggcggac actctcacac
     3721 cttccttcaa gaactccttt atgtgaaaaa tcttgacgga aaagaaatcg gaatcgacca
     3781 aaatggcaaa tcggcaatct ttgtaggcaa aatgatttta gatttgaaaa agaaataatt
     3841 gagcggtaaa aagcacgata atgtaaaatc taataattgc ttcattctgt ttataaccag
     3901 agagttgcac aataatagta tcaggatata agtgaaagaa taagtgagta aaatactaac
     3961 ttcatttttt tacttctaag aattaaaaaa aatatgaatc aagaattaat caactctctt
     4021 tcggtattac aatccgaaat gaaagaatgg atgagtgccc ttcatcaaca cccagaattg
     4081 tcaatggaag agcattggac ttcccaatat attgcatcaa aacttgaaga atggggctac
     4141 gatgtggcaa aaggggttgg tggaacaggc attgtggctt ccatgactgt tggcaatgga
     4201 acaaagtcta tcggattaag agcagacttt gatgcagtgc ctattgctga agacaacaat
     4261 ttaccttata aaagccaaaa cgaaggcata gcccatcttt gtggacacga ttcacactct
     4321 accatgttgt tgggagcggc taaatattta tccgaacata atgattttaa cggaactgtt
     4381 cgtttcatct tccaaccagg agaagaaacc atgcaaggag gaacatcaat gattgccgat
     4441 ggactctttg aacgtttccc cgtagatgct gtatatggta tgcataatat gcctggattg
     4501 gaacttggaa agttttattt tcatgaaaat gaaaccatgt cagcggtaga caattgggaa
     4561 atagaactca ttggtaaggc ttcgcatggc tcgatgcctg aactcagcat tgacccattg
     4621 gtatgtggtg cttcgttagt catggcattg caaactattg tgagtagaaa tatttcacca
     4681 tggagcaata cggttgtaaa tgtgggcgca tttaatgctg gcgtggctgg taattcagta
     4741 cctcagacgg caacccttca acttagtatc cgcaatatgg attcgaaagt acgtcaattc
     4801 gtgcttgacc gtattcgttt cattaccaaa gctcaagctg aaagctataa ttgtgaatac
     4861 aaaattcacg aaggtgtagc aggaacagtc ttaatcaata cacccgaaaa cactcgctgg
     4921 gcggctcaag tggctcgaga tacctttgga aacgaccaag ttagcgagga tatgcacccc
     4981 tatatgagta gcgaagactt tgctttcatg ctacaaaaaa aaccaggaaa ttattgtgtg
     5041 atgggcaatg gcgatactca gatggttcac catcctcatt atgttttcaa tcaacaaatg
     5101 ctttcgagag gtgcaaccta ttgggttgca ttagtgcaag aatacttaaa gaaatagttt
     5161 tttattttat ttataggctg gttctataaa ttagctttaa acgtatttca taaaaattta
     5221 atgactatat gcggtggtaa tttatagaac cagcctataa tatctttttt gataaaagtt
     5281 actattttgt actccaaaac agcctatttt acacttcaaa acaggctgtt ttggacgaca
     5341 aaataggctg tttcgactaa caaacaaata gctttcataa aatagtatgt attaactgac
     5401 tgaataagct gtataaataa agcctttttt attatttttt tataaagaaa cgacttggct
     5461 tatttcatga aggcaaggaa aacggctaag atgaggcagg cgaaggctgc gaaatggttc
     5521 caatgaaggc tctcgccatt gaaaaaaaca actgtaaaaa tggtgaatac gaccaaagaa
     5581 atgacttctt gaatgacttt tagttgcatg agtgaaaaag ttccgtcatt gccaacgtag
     5641 cctatacgat tggctggcac ttggcaacaa tattcggcta aagccaatcc ccaactcatg
     5701 agaatgacaa aataaagggg cgtattgtcg gatataacct tgatttgttg caatttaaga
     5761 tgcccatacc atgcaaaagt catgaaaata tttgctacaa tcaataggcc tattgtataa
     5821 aatccgttca ttttaatttg ttatttttgt ttttcgaccg caaaagtaag taaaaaagca
     5881 tagattatgg cacaattccc actttaacat actgctatta ggaagaaaaa atgtattttt
     5941 gtggcaaaca atagacccac gaagcaatga aacaccctat tatttttacc gctgaattgg
     6001 aatgtacgtt gtcgcaattc atagatgaat gcaagcccga caaggtgttt attcttaccg
     6061 acgacgtaac cattgaggct tgttatccaa tagttcagca tttctattgt cttaaaaatt
     6121 ccgtctgcat caccattccg agcagcgata acaataaaac tttagggtca ttgacacagg
     6181 tttggaacta tttgcaaaag gaaaaagcaa cacgccactc actgctgata aatcttggtg
     6241 gcggaatgat aaccgatttg ggaggctttg cggctgcaac tttcaaacgt ggaatgcgtt
     6301 ttatcaatct tcccacgact gttttagcga tggttgatgc aagtgttggc gggaaaacag
     6361 gaataaattt cggtggtctg aaaaatgaaa ttggggcttt ttgcgatgcc gaagccgtgt
     6421 tgattgacac gaaatggctc aaaacgttgg ataaggaaaa cattttgagt ggttatgcag
     6481 agatgttgaa acacggattg ttatcagaac gaagtcattt gacagaactt ttaaccttcg
     6541 atatagacga tattgacttg aaaaagttgt tcgctcttct ggaaaaaagt gttgaagtaa
     6601 agaaaaaaat agtagaaaaa gacccacacg aacagaacat tcgcaaggca ttgaactatg
     6661 gtcatacatt tggtcatgcc tttgaatcgt gggcaatgcg ccgaaatcaa atcttgcatg
     6721 gttatgctgt ggcttacgga atcgtttgcg aattgtatct ttcagtggtg ttgcaaggtt
     6781 ttccaacgga agtaatgcgc cacgtcgtaa actttattaa agcccattat ggtgtgcttc
     6841 caatttcgtg cgatgattat ttggagttaa tttcgctcat gcagcacgat aaaaagaatc
     6901 acggtggcac cattaacttc acgcttctgc aagatgttgg taaaattgct atcaatcaaa
     6961 ccgcaagcga agaaatgata agagaggcat tagacttttt gagggaagga taaaaacata
     7021 tatcgcctat ttttcatcat gaaaagtagg cgatatatgt ttaaaaaata tgatttagaa
     7081 tcgtattttt attaaaattc taattctaac cctatcatta attcttcggg agcaaagcgc
     7141 aaaccaaaac cagttgtgcc tattttaggc tcttcgccac catgatagtc gtttcaatag
     7201 cccatgaaac ccatacgcag acaaaggcaa agtccttcgg ttaggtctac acaagcacct
     7261 ggacgaatgc ctatttcaaa gccgtggcgg tcgtttttca ctccattagt ctttgtttta
     7321 ccaaaatcaa aacctaaacc gctatctaaa aataagttga acggtccatt gtgaacataa
     7381 taccaacgca cgaaaggagc tattttgaaa gcattagaag ttgtttttat tccgtcttct
     7441 gtttcttttt catattcgta agcaagcata atccctgcgc cccaagtatt attaaaaaga
     7501 taaccaactt ctggactaaa gtcaaaagta agacttttgt catctggatt gttccaaaat
     7561 gttaaggcac ctcctgcaaa tagtcaccca tgagggtcat cattgtgcga aattgtagtc
     7621 tgtggaaaag tgttttgtgc ttggatagat aatccaacga acatacaaat taagagtaaa
     7681 agttgctttt tcatttatta aaatatattt gtgatgcaaa aatacataga cctttttgaa
     7741 tgggcaatac ctaataattg tgatttgtgt aatttttcgt cagccgtaga ttagctgtta
     7801 catgcaattt ctaaaacttt tgcccgtgca attttgccag tttcagtagt tggtaagctt
     7861 tgtacggttt tgtaaaatgc tggttgccaa tagcgtggaa gcttatcttg acaaatagaa
     7921 cggacagaat cgagcgagtt tgattcggtt atgaggacta tttcctcacc aaattttttg
     7981 ttaggacgtt tggttattgc aaatggcgca attagataag ggcgcaaagc acgttcaatt
     8041 tcttccattt gaatttttat tccaccagaa ttaatggtgt tatctttgcg acctaagatg
     8101 cgaaatttag ttttgcctga tgctgtttgc tgcaattcag ctatgtcgtt ggtttctaaa
     8161 aggggaagtt ggctcaccat aggggctgct attgttaggc aaccatcgtt attgagcgac
     8221 acttttacac cattgaaagg tgtgtaccac tcgctttttt cttcgccatt aaggcgtctt
     8281 aaagcgatgt gcgataaggt ttcggtcata ccgtaggtac tccacaccgc atttgggaag
     8341 tcttttaatt ggttagatag gtcggtgtca atacttccac cacctataat caaatgtttt
     8401 atggctttca gtcgttcgca ttcttctttg tttttcagcg tgttgaagac ttgcaaaggc
     8461 accattgcgg caaaggttat gctttcatca gggttgttta aatcggctaa cgagtcgttt
     8521 gaaagaggat ttcccgaagg tttcacactc aataatttaa ggtttcgctc aatacttctt
     8581 accaccatca ttttgccagc aatatagtct aaaggcatac agagtagggc agtgtcgcct
     8641 ttttctaaac ctaaaaaatt gcaagtgatg cgtgcagagt tgagcatgcg tgctttttcc
     8701 acacaaatag gtttcggttt ccccgtagac ccactcgtat gtacggttag ggtaggggaa
     8761 acgttgtgcc attcagcgag aaattcttgt aaagtcatct tgtttttgcc agcaaataat
     8821 tgattatacg atatgtatgt gggcttcttt ctgggaaatc catagttggt cgccacgaat
     8881 ttcgagtggc attgcgatgt tgtcagcaaa caattgtccc gttcctaagc cttgtgcgtg
     8941 agtaattcca ctgccataaa tctttgcagt gagttgggct attgcgttta accccacgtt
     9001 actttcgaga gcagaagtaa tccacgaacc catatttcgc tcgttagcca attcaatcca
     9061 ctcttttgta cctgccattc cgccatgtaa tgaaggttta aggataatgt attgtgggcg
     9121 aatggtttct aataattcca ctttttcgtc atgttcgttt accccaatga gttcttcgtc
     9181 aagcgcaata gggaggggag tattggcaca aagctgcgcc atttctgccc attggtgctg
     9241 tttgatgggt tgttctatgg aatgaatatc atatttggct aaggcttcca atcgtgagag
     9301 agcctctttg ggcgaaaaac caccattggc atcaactctt aattccacat ctttggcact
     9361 aaacgactga cgaatgtggc gtattaagtc caattctcgc tcgaaattga ttgctccaat
     9421 ttttagtttt acgcaatgaa aaccttgttt taactttgtt tctaaacgtt gaaacatttc
     9481 gtcaaaagtt cccatccata ccaatccgtt gattggaata ccttctttgc cacgcccaaa
     9541 aggagtatcg aagaagttta aactgccctt tgaaccgagt tgagcaactg ctgtttcgag
     9601 tccaaagagc atagaaggat aattgcgcat ggcttcataa tcgataattc ctgtcctttc
     9661 gtaatcgtta caaaaggctc ttagtttgtt ttcatactcc ttttcgggca tagcatcgca
     9721 cgaaaggtcg ggcaaagtaa cacattcgcc aatgccaacc acccctggtt cttcgtcgga
     9781 agtgagcgaa atgtagaaac tttggcgtgt cttatagaca ccacgcgatg tttccgcagg
     9841 ttgcagaaag tgtaatattt tagaaattat cgttattttg cgcatcatta tggttgtttt
     9901 tagagaagta atattatttt ctcttaatcg gttgtaatgt tgtcggtaag atgtaggggc
     9961 gtgatttttt acgcaaacaa gtttttgtaa gcataattac ttatgggaat tgaggatatt
    10021 tgtcgaagtc tggtttacgt ttttctaaga aagcacgccc tccttcttgc gcttcgtcca
    10081 tcgtatagta gagcattgtg gcatcgccag ccaactcttg gatacccgct tgaccgtcta
    10141 attcagcatt gagtcctgcc tttatcatgc gtaaagccaa tggagaacgc tccatcatgg
    10201 tctctgccca cgctacacac tcgtcttcga ggcgatcgaa tggtacaact ttgtttacca
    10261 atcccattct ttcagcttca acggcagagt attggcgaca cataaaccat atttcgcgtg
    10321 cttttttctg tccaacgatg cgtgccaaat aagaggctcc gaagccagca tcaaacgaac
    10381 ccacctttgg acctgtctgt ccgaaaatag cattgtctga cgctatggac aaatcgcaca
    10441 ttacatgcaa cacgtgtccg ccacctattg caaaaccatt gaccatagca atgactggtt
    10501 taggcaaacg gcgaatttgc atttgcacat ctaaaacatt caaacgaggt acaccgtcgc
    10561 ccccaacata gccgcctttt ccctttacat tcatatctcc gccagcgcaa aaagccttgt
    10621 cgccagctcc agtaagtatc acaacacgaa tgtcgagtgc ttctcggcaa tacgaaaagg
    10681 cttgcgaaat ttcccaaacg gttagcggtg tgaacgcatt acgataacgt tcacggttga
    10741 tagtaatctt tgcgatgtga ttatattcct cgaaaagtat ttctttgaag tcgaaacctt
    10801 caatgctttt ccattctcta tttgccatat ctgtatgttt tatttattgt tcttttttat
    10861 ttcttcattg aaagtttgcc acgctgctgc atcggtggca gtatcggtaa atatttccaa
    10921 taggattgga ctatcttttt gattgaaaaa ttgttccaat cctgtcttca attcctttga
    10981 attagtagcc gaaagatagt gaatgccatg ggtttggcat gcgccctgtg cggttacagg
    11041 tagcccactg cccataattg tggcacgatg tgccgacttt tccaatcctg gaagttgcag
    11101 gaaaattccg ccaccgctat tgttgagcaa gaggatagca aggtttttat gtaaattgtt
    11161 gttccatagt gcattttggt cgtagaaaaa actcaaatcg cctatgatac agaatgtttt
    11221 tacggtagga ttggcagctg ctaagcccac tgccgtagac aaagaaccat ctattccgtt
    11281 tacgccacga ttaacaaaaa tgtagtcaga ggaatagaaa ttgcccaaac gaactgctga
    11341 actgttgcca taaaccactt gtcgttcgac tttatattgg tttaattttt cgtgaaatag
    11401 ctttgtggca agcatttgcg aataggttgg gacatagttt ttggcgatat tgccaacgcg
    11461 ttgtccctcc ttttgccaca aattataata attagaagat tttatcgcct ttgtttcagt
    11521 tgccaaaagt ttgataaaat cgatagtaga gcattgaaca gcatcggtaa gattcataaa
    11581 cgtatcacga atttcgcctc gtgggtcaat taaaatagag tgttcgggat tgctattcct
    11641 taaaaaacgc ttcaaaagtt tgcttacaat cgttccgccc atatatataa taaggtctgg
    11701 tcgcaaggct tctatgttat cggtcgatgc caaaagcgca tcaatggctt gtggctcggc
    11761 ttcagtagcg tcggaaagtt tgtcttgaac aatgacaaat cgtttgcgta acgcattgat
    11821 ttcatgcttc accgcctcca ttctatttcg tgcttcttgc cctatgacga tgagaggacg
    11881 gtcgcatttg ccgatgtttt caacgatttt gcgtgctgca ttgctatcgt ttatttgttg
    11941 cgaacacgtt atttttcgtt caaggggtag tttttccaca tcatagttga acaatggttc
    12001 gctaataggc acgttgatat gcacggggcc atactccata cggctgcatt ctatcaaggc
    12061 ttcgtttacc aaacgattgc aaaaccaatg ttcctcctcg tcttttggct caggcaggtt
    12121 tacacttttg cgcacaaacg gacttaaaac attggcttgt ggcatggttt gtccgtcgcc
    12181 ttgttctatc cattgcgcag gtcggtcggc agaaataacg attaaaggaa cgttctgata
    12241 gtaagcctct gccactgctg gtgcaacatc taatagggca gaccccgaag taacgcatac
    12301 cacaacaggt ttatgtttgg ctaagctaac gcctacggca aagaatgctg ccgaacgttc
    12361 atcggtaaca gggtaacaaa ccatgtcttc cgcctcgcaa aagttgtgaa ccaaagccga
    12421 attgcgcgag ccagggcaga ccacaatatc ggtaatgttg tgttgtatga gcaatgcggt
    12481 aagaatatta acgttatctt tgttactgaa cataattcct tttctttttt tattcaagca
    12541 attggcgcat agtagccaac tttgcttcgg tttcttgcca ttcgctttcc tctgtactat
    12601 cggtcaataa tccgccacca gcatataatc ggcattttgt ttccatgatt tccatgcaac
    12661 gtaatgatac gtaaagatgc gtgtttccgt ttaaatttaa cgctccagca aagccactat
    12721 aatagcgacg tggggttgtt tcgttgtcaa gtataaactt tcgtgctatt tccttttcta
    12781 ttccacaaac cgcaggggta gggtgtaatg tgtttaagag tgtccctatt tgcgtgttat
    12841 ctttcaattg gaatttaaaa tcggtgcgta ggtgtgccaa attagctgct tgtgcggtgt
    12901 aaactccttg ctcttcaatg tcggtggcgt gctgttccaa acactggcga atgtattttg
    12961 ccacgtattg ttgctcggct ttgttctttt ccgaccatat tatttcgtcc gattgatagg
    13021 gcattgtacc tgctaatgcc attgttttcc aattcgaact gttgccatcg agcaatattt
    13081 cgggtgttgc catgagccat gtacccgttt gaggagttga aaacaaggct acaaattgac
    13141 gtggatagcg ttggcaagca cgccaaaata tttcttctgc ttgcaagttg cttgattttt
    13201 cttcttcaac gcaacgtgat agaacaattt tagagaatct tccattgcat atttgttcat
    13261 gaaaaactgc aaaatccttg tgataatcgt ccctatattc cttcctttcg gttggcttaa
    13321 cctccttttt taatatggtt tcgggttgct ttactgccaa ggtaacgact tcttctggtt
    13381 gcaaaagaag aatagggcat tgagcagaag gcataaaagg cacaatgaca aaacctgttt
    13441 taccattcaa atcctgtaac gatgcaacct cgagtggtgc agtttgttgc accatttttg
    13501 tacattcttt ggcgtaaggc aatcgatata tggcaaaaga cctcatagat aatttctttt
    13561 taccttattt tttttgtttc ggattgatga cataattggt tacactcaca gttgaaatga
    13621 tttctccctc atcgtttttc acgtctactt gccacacatg gagcgtttta cctttatgta
    13681 caagtttgcc aaaagcagta acagtgccac cgtagggcat ggcttttaca tggctgccgc
    13741 taacgtttat acctaaagca accttgccag ggcagagtgc taacgaccct acgccagcga
    13801 cattttcagc caatgctaac gtagcaccac ctgaaagaaa gccaaaaatc tgtttatttc
    13861 tatcgtctac cgccattttt gccatgagcg tatcaggttc gggtgtagat aggaagcgca
    13921 ttcctaacgt acgacttaat ccgtcttcgt tttccaaagc tatgcgatgt ttttctatat
    13981 ccattatttt tctatattat aaaatatgaa atccttgtta ttggcaacca ttttcgtgta
    14041 cgagtgaaat tatgccttat gcaaagataa taaataaatt gcgcattcgt aaaggaaata
    14101 ctgtttttgt ttcctataaa ttaaaataag gtagcaaccc ttggcggata gctaccttta
    14161 tttcttttcc gttgttatct atttggaata ttattttaca acaattttct ttccattatg
    14221 gatataaata ccgtgagtag ggtgggttac acggcgtcct tggaggtcgt aatagtatcc
    14281 atcaccttgt tgttgcgtgg ttgttacgtt ctctattcca gctgggtcaa gtattgaata
    14341 agtgaattta atcgttccat caggattaac aacaatgttg tttacaggct gtccaataga
    14401 ctttcctgtc caaaaatcaa agatatctat ctgctttttg ttcactccaa ataaatgttc
    14461 acggcgagca ttaaaactta acttctcgtt attagctgta acaacgtatg cgtgtttaaa
    14521 attgtaatcg ttgtttacta cgtttttatc ccaagtatat ttatcgtatg agaagtgggt
    14581 gagcagcaaa ccattaccaa aagtgcaaat atcgccgtag gtatatgatg ctggatacca
    14641 tgtatctgta tggcgatttt ccataatgaa gtattctttg ttattttctg ggttgcgaac
    14701 caatgctgct aatgttccat ttggattgct tacagggtcg agaactactt cttctgtttt
    14761 tttcaactct ttaatatcca accaacctaa gtaagaacgt tcgtatgcag tatagccgat
    14821 aggtgcacgt gcatcgttta cataagcacc accgtccatg atagaccaaa aaccgaatgg
    14881 gtcatcgcca tctgtgtaat agtctgtttt atagaagtcg ggtaaaccta aagcatgtcc
    14941 aaactcatgg cagaatatac ccatacccat taatttgttt tcatggtcta attcgttacc
    15001 aacgaagaag gaattaaagt gcgtattgcc aatggtttcg ttgatatcgt tttgacatgg
    15061 ccagattaag tctgctgtat tagggtctgc attgctttct gtagcttgtc cttttccagc
    15121 ataaagaatg cacaccaatt gcacttttcc atctttatcc ttaaagttgt caaatttata
    15181 tcctttggct gttgccgcat ttacggcatc tcttaccaat ccgtcaatat cagaatcttc
    15241 atcataaatc gttcttttgc cgtatgtttt atagctttta ttaacgttta caggacctaa
    15301 aacttcaaaa gtaggtacaa attttccacg actttgcgaa gtaaagtaat cttttaccga
    15361 ccccttgcat agtaattcgt ccttgtatcc cacttcgtta taaaagcgtt ccaacttttc
    15421 ttttgttgtt ttcgcatcaa attttgcatc ggtaaattcg accatgatta caggaatagt
    15481 tggggtgcca atgctattaa cacctcccgc tcctgttgta ttgaatttac ctaatccgtc
    15541 atctgttgag gcatgaatgg ctttgagagg tgcatggcgg gcatgtcggt gagtggtatg
    15601 taatatactc aatttattgg ctacatcatt attgttcaaa aatgcttttt cttcgttaga
    15661 acgattacca gcttcgtgcg caatgtattg tgaagcaacc aattttccat cttgtatcat
    15721 agcgtaagct aaatcaccat tggcattttt taccatgaat ttcccgtcca atgtggtgaa
    15781 atattctact cgttctactc cgtgttggcg gaatttcaat aatgtgccat cactttgctt
    15841 tgtagtccaa attcgtggcg aaggaccaat tgcgaatgtt ggaagtattg ttgcagctgc
    15901 gaaaagtgct gaaagtaata ttcttttcat aaaattgttt tgtagatgtt actttttaaa
    15961 aaatgaataa tgttacaaat gtaaccatta tttttaaaaa atccttatgt ttgaagaaac
    16021 aaatcacaat tagttatgtt ttttacattt tatctacaga aataaaggta acactccttg
    16081 ggggaatgcc acctttatct ctattttatt gtaacctatt tgtacaatta ttttataaca
    16141 attttctttc cgttgtggat ataaatacgg tgagtgggtt ggttacgcgg tgaccttgga
    16201 gggcataagt tttatttctt tgtaattgaa aaatatattt cgagagaaat tttccaatac
    16261 gttttatagt taaaaatagt tttattttag attaaatgtt aattttaaag ttgctaaaat
    16321 tttggctcta ataattccta aaatgtgtag taaattgtgt agatggctat tttgaaatgc
    16381 aaaagcatag gttttgaact gcaaaagcat aggttttgaa gggagaaaag gtgattttta
    16441 gatagaaaca tgtggctgat ttatttgaaa aatagttctt ttggtattat gttttgttcc
    16501 ataggtaata taaatactgt atgattattg cacaaaaata atttctttga agcaaggtgt
    16561 tgatatgtaa tgttttatca ttgcacacga atagagacta aattcataga aaaatatttt
    16621 ttatttttga atacgggacg tatgatagtt atatgttgga tttaaattaa caaatagctt
    16681 gtgtggtaaa cagaaattaa cgtaattagg ataagcgaat ttatttgtta atttcaatat
    16741 attgcacgct ttcggaaggt cttgcataag ttcttgacac taaaaaaggc taaaacacca
    16801 attatttgca aataatttcg tacttttgca aattataaga ttatacttcg attaaaataa
    16861 aatgaacgtt ttagaattat cagaacaaga gattgtacgc cgtcagagct tgcaggaatt
    16921 gcgcaacatg ggcattgacc catatccagc agcagagttt ccaaccaatg ctttttcaac
    16981 ggatataaaa tcggaattta aagaagacga aaagcgtgaa gttgtcattg caggtcgcct
    17041 tatgggtcgc cgtgtaatgg gtaaagcttc atttgcagaa atacaagata gcaagggtag
    17101 aattcaagtt tacattactc gcgacgacct ttgcccaggt gaaaacaagg atatttacaa
    17161 tgtgttattc aagaaattgc ttgatattgg cgatttcgta ggcattaaag gctatgtctt
    17221 taaaacacag atgggcgaga tttctgtcca tgcccaagag cttactttgc tttcaaagag
    17281 cttaaaaccg cttcctattg tgaaatacaa ggacggtgtt gcttacgata aatttgacga
    17341 cccagaactc cgctatcgcc aacgctatgt cgatttagtg gtaaacgaag gcgtaaagga
    17401 gactttccaa aagcgtgcta ccgttttgag aaccatgcgt aacttctttg acgaagcagg
    17461 ttacacagaa gtggaaacac caactttgca gaccatagca ggtggagcaa gtgcgcgtcc
    17521 atttattacc catttcaatg cgttgaacac tgaaatgtat atgcgtattg ctaccgaact
    17581 ttatctgaag cgattaatcg taggtggctt tgaaggcgta tacgaaatcg gaaaaaactt
    17641 ccgtaacgaa ggtatggacc gtttccacaa tccagagttt acttgcatgg aactctatgt
    17701 gcaatacaag gattacaact ggatgatgag tttcacagaa cgtttgatag aaaagatttg
    17761 cacagcggta aatggaaaac ctgaaataca agtgggcgac aaactcatta gctttaaagc
    17821 accattccgt cgccttccta tcctcgatgc tatcaaagaa aaaacaggct tcgacttgaa
    17881 cgataagacc gaagaagaaa ttcgcaacat agctgtaaac gaattaaaat tggaaggtat
    17941 tgatgcaagt tttggtaagg gtaaactcat tgacgaaatc tttggagagt tttgtgaagg
    18001 ttcttacatt cagccaacgt tcatcataga ctatccagtt gaaatgtcgc cattgacaaa
    18061 gatgcaccgt tctaagccag gacttacaga acgtttcgaa cttatggtaa atggtaagga
    18121 attggccaac gcttactcgg aattgaacga ccctatcgac caagaagaac gtttcaaaga
    18181 gcaaatgcgt ttggctgata atggcgatga tgaagcaatg ataatcgacc aagacttcct
    18241 tcgtgctttg caatatggta tgccaccaac atcgggtatc ggtattggta ttgaccgttt
    18301 ggtcatgttg atgacaggtc aggaatacat tcaagaagta ttgctcttcc cacaaatgaa
    18361 gccagaggca aaaataccac aaagcagcat caaagaatgg gctgaaatag gtgtgccaga
    18421 agaatgggct tacgttttgc gcaagtgcgg tttcaatttg attcagaata tcaaagatga
    18481 aaaagcacaa ggtttgcaac aaaaaattgg cgaaatcaat aagaaatata agcttggtta
    18541 tgaaaaacca tcggttgatg aaattcaaca gtggattgat aaagcacaat aataaaacaa
    18601 ggaggggcta agctcttcct tatcctaaaa acatgtatga cgtaggaaat atagcaatca
    18661 tcggaagcgg aagttgggca acagctatcg ccaagattgt ggtggaacat acccaccaca
    18721 taggttggta ctttcgacgc gacgaatcga tagagcaatt taagcggtta ggacacaatc
    18781 ccacctattt gacgagtgct catttcgata tcaacgagat tagattatcg tcagacatca
    18841 atcgtttagt gcaagattat gatacgttaa ttttcgtaac accatcgcct taccttaaag
    18901 gtatattgaa aaaggtaaag cataaattgc atgataaatt tatcgtagca gccattaaag
    18961 gcattgtgcc agacgaaaat ttagtatgtt cggaatactt taataaggtg tgtcatgtgc
    19021 cagaggagaa tttggcagtt attggtggtc cctcacatgc cgaggaagtg gctatggaac
    19081 gtctcactta tctaacagta gggtgtaccg accaagaaaa agcacacgct ttgaccgata
    19141 agttagtgtc caattatgtg aaaacaaagg tttcacgcga tgtgcttggc attgaatatg
    19201 cttcggtttt aaagaatgtt tatgccattg cctcgggtat ttgctctgga ttacaatatg
    19261 gcgataactt tcaagcagtc atcatttcga acgcaatgca agaaatggaa cgcttgttaa
    19321 gtagcatcaa tccaatgcaa cgtagcatgg tggatagtgt ttatttgggc gaccaattgg
    19381 ttacaggata cagcaatttt agccgaaacc gcactttcgg catgatgatt ggtaaaggat
    19441 acagcgtgaa atcggcacaa atggaaatgg aaatgattgc agaaggttat ttcggtacaa
    19501 agtgtatgaa ggaaataaac cgacacttgc atgttaatat gcctatcctt gatgccgttt
    19561 acaatatatt atacgagcga ataagcccgc aagtggaaat aaaattatta acagattcat
    19621 tcaggtaaaa taacatggaa atgattaaat tagacatttc aaaagccgca caggtattaa
    19681 atcctggtac ggtagaagcg tatgcaccac aagtagctgc tgcacaagag gctttggaga
    19741 aaggaacatg cgcaggaaac gactttttag gttggttgca tttgccttca agtgttacgg
    19801 aggagttcat caatgaagta gtgggcgtag ctaacacatt gcgcgaaaag tgtgattatg
    19861 tggtagttgc aggtattgga ggttcttatt tgggtgctcg tgccattatc gaagccttag
    19921 ataatagctt cgcatggttg ttgaaggaaa agaaaaatcc tacaattctt tatgctggca
    19981 acaacattag cgaagattat ctttatgaac ttactgactt tttgaaagat aaacgatttg
    20041 gtgtcattaa tatttctaag tcaggaacaa caaccgaaac tgcgctcgct ttccgtttgt
    20101 tgaagaaaca atgtgaaaat caacgtggaa agaatgaagc aaaaggtgtt attgtagcca
    20161 ttacagacgc tgaaaaaggt gctgctcgca ctgctgcaac acgtgaagga tacaaaactt
    20221 ttgttattcc tgacaatgtt ggtggtcgtt tctctgtgct tacacctgtc ggattgttgc
    20281 ctattgcagt agcaggattt gatattcagc aactgattaa gggcgcacaa gatatggaag
    20341 aggctacatc tgccaatgct ccatttgctc aaaacattgc tgctcgttac gctgcgatac
    20401 gccaagcact ttattcacag gcaggaaaga agatagaaat catggctaat ttccaaccaa
    20461 agctacactt tatggctgaa tggtggaaac aactttacgg cgaaagtgaa ggaaaggaac
    20521 aaaaaggtat tttccctgcg gcttgtgatt ttacaactga tttgcactct atgggacaat
    20581 ggattcaaga tggcgagcgt tctatctttg aaactgtact ctctgtggaa gaaaccaaca
    20641 aaactttgct tttcccacac gatgatgaaa accttgatgg tcttaacttc ttagaaggaa
    20701 agcgcattga cgaggtgaac aaaatggcag aacttggcac acgattggca cacgttgatg
    20761 gtggcgttcc aaatattcgc atcagtattc caaagttgaa cgaatattat attggtcagc
    20821 ttatttactt ctttgagaag gcttgcggta ttagtggatt ggttcaggaa gtaaatccat
    20881 ttaaccaacc tggtgttgag gcttacaaaa agaatatgtt tgcattgctg aacaaacctg
    20941 gatatgagga agaaagcaaa gcaatcagaa aaagattata aaaaataaag cccattcctc
    21001 atattaagga gtgggctttt tagttgcaat aaggtaaaaa tgtttcaaga agcaattgca
    21061 caatacaacg aaaaaacgca acaatttttt gctccaaagg tggttctttt cgatatggac
    21121 ggggttcttt acgactccat gcctactcat gcaaaggcat ggcaaaaggc tatgaaggag
    21181 tgtggcatca cttttacggc tgaagatgct tacgcgacgg aaggggcacg aggagttgat
    21241 acggttcgga aatatgccaa agaacaatgg ggaaaagaaa tttctgaatc ggaagccgaa
    21301 aaaatgtacc aactgaaagc gcatattttt caagaaatgc caaagacaca tatatttgat
    21361 ggtgtgatag acttgatgaa gaaaattaaa tcaagtgggc taaaaatagg tattgtaaca
    21421 ggaagtgggc aacgattgct gatagaacgt ttgctatctg actttaaaga ttttatagac
    21481 gaaagtcaag taaccacagc cttcgatgta aagcgtggaa aacccaatcc tgacccttat
    21541 cttgcaggac ttaaaaaggc gggcaatttt gctccgtggg agggtattgt tgtagaaaat
    21601 gccccccttg gcgtccgtgc tggtgtggct gcaaaatgtt ttacaatcgc tgtaaatagt
    21661 ggtccgctgt ccgatgaaac attaataaac gagggcgcaa acattctttt ccatactatt
    21721 aaggacgttg ctaatggttg ggacgaactt ttgaaagtta cgaaagctta gaacatacac
    21781 tctcttgatt taaaaaggtt actttacttt gtaaaagatg cgagagaaca acacaaagaa
    21841 aaggcgagta tatcgaaatt tcgacatact cgcctttcat attaatactt atcgtttctt
    21901 aaatctctaa tttatgaagg acaatttatg cgtcctatgt tatacatttc taatgccttt
    21961 acaaaataag gtataatttt attgcttgct aattttttca tcattttcat aatcaatccc
    22021 tttacattta aattactaat tcacgaggat atcctttaac ctctcttttc tctattgaag
    22081 attaataatt cgaagcatta ctttgaatta tacgatgcaa aattacatac attctgacaa
    22141 aaagaaatca aattaaggtg aaaaatgttg ttttgagccg tttgttttga cttttgtcaa
    22201 tgtgtttgat ataaatcaaa gcaaaaagaa aataacatgt tataaccaaa tctaatgcaa
    22261 attaagctaa aatcacatgt ttattatata ttatggtgat ttccttcaaa gtaagataga
    22321 tgaatttcta cggaagagtg attcgtttga tatgaatata gaacaacttg agggtaatat
    22381 ttgcaaatgt acttgattta agacaaaaac attcgctctt tggttcacaa aaaatgtaaa
    22441 acacttgagg tatatttctt tgttatttaa ttttgcgaac gaataagata aatataaagc
    22501 cacagaatta tgaaaaagaa aattattttt ggattagcat taatagctat ggtattgagt
    22561 tttacatcat gtaataagga taacgatgaa atagtagaaa caaacgcttt ggtacataca
    22621 acttggagct atgagaaatc aaactttaac ctgcaaggta atttaaagcg ttggggttcg
    22681 ctccaatttc aaaccaataa agatgttgtt gtaactgctg gttatgaata tcaaggcgaa
    22741 caagacaatt ttggaaatta tcatggcgct tataaccgca atgaaacttc gctacatggt
    22801 atttatgaat acaaagcacc taatctgacg attacactta atgctgaaga tggtcagcca
    22861 gcgaaaactt taaaatatat tgttgacgaa aaagcaaaga ctattttgcc tgttagcaac
    22921 gcaaactctt ctgacgaagt agtttataga aagaaataga ttcataaaaa cgatagacat
    22981 tgatttatat tttccccgtt ctttttctat aagagcgggg gattttttat tttttgaact
    23041 gatatttctt caacaactat tccgatttca gccttttaca aaaggattag aacaagtttc
    23101 aaacgataat atttcagtct tttcatctgt cttaaagcaa ttgaaacaaa aaacgaccca
    23161 cttagcatga actaaatggg tcgtttctta taggtttaaa tatcttattt gtagatttca
    23221 gccaatttgt tcaacaagtc ttcgccacgc aaatcgctat ctacaatctt accttctggg
    23281 tcaagcaaga tgtttgaagg gatagagcga atgccataaa tcttgcctgc tgcacattgc
    23341 cagcctttaa ggtcagacat ttgtggccaa gtcataccga gtttcttaac cattgctgtc
    23401 catgcttcct tcttttggtc gaagctgaca ccaacaattt ctaaaccttt gtcgtggaaa
    23461 cgcttgtaag cctcaactac attaggcatt tcttgacggc atggaccaca ccaacttgcc
    23521 cagaaatcaa cgaatacata gttacccttg ccagcgaatt ggctcaactt gatttcctta
    23581 ccgttcatat ctttcattac caaatcggtg tacataagac ctggacgacg gagttctaat
    23641 gatgcaagga agtcctttgc attcttcaaa ctttcttcat tgtaataacc acttgtaggg
    23701 tcgagaacct ctttgagttg gtcgtaagta aggtttccat agacatcacc tacatatttt
    23761 gcaggaaatt tggttgcttt gaatttcttt gcaatttcaa gtgtagtagt tgtaaagata
    23821 ctggtaagtg aatcgtcttt tgctaacaac tcttcagcgc gctttttatc ggcttctgta
    23881 attgcatcgc ctttttgacg aattcctgca aattcttttc ctattacttc aaactcagcg
    23941 tagagtttgt tcattttctc ttcgtaaggc ttaaagtctt gcga
//
