LOCUS       NZ_JH660660.1          24097 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JH660660.1 Prevotella bivia DSM 20514 Prebiscaffold_3, whole
            genome shotgun sequence.
ACCESSION   NZ_JH660660
VERSION     NZ_JH660660.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:49:03
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1243456
            Orig. end    :: 1267553
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24097
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1253456:1257553]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14097
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..24097
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24097
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_fatty_acids"
                     /region_number="3"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             540..1688
                     /locus_tag="ctg3_1042"
                     /transl_table=11
                     /translation="MLIYILVFIVAFIYYILSRKNSFLRKSSVVLSFFFLYVALFVGLG
                     DMIGGYDRYIYGEVFDTIADEFQHTSSPNINKIIYLVGGKEYGYFFWQILLSYITQNRY
                     IFILITTIAIYVLFFLAFKEYLDDYPLACIVFLGLLYYFSMTYLRQVIGVGFTFLSVKY
                     IVKRKFLPFFCFWLLAYSFHGSALIFFPMYFIPQKKYSKNFVITVLLLCLIVGLTPLPN
                     ALLSSGVTASGKAQNYMDQDQGFRIEYVIEVVAFISIFFMNYGKINKEKQTLVFLNMSY
                     VFCALLLLFMRFGQGGRLGWYFMPGIIYMTTYLCNRKDVAKWLKPAMILLFFGLFFRIT
                     LAWRAFNVPYKTFLTNGQPAGDGSTYEKYEYDERYTIDKFFR"
     CDS             1688..2614
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_1043"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.3e-27,
                     bitscore: 93.3, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITVFTPTYNRGNLLKRLYDSLCNQSFKDFEWLVVDDGSTDNTGE
                     LMKQIMTDGSNKFVIRYFKKANGGKHSAINFGVKEAKGELFFIVDSDDILPPFALQDVI
                     DVWHNIYNKEQYAGVCGLDGYLESEVVIGSGFPRKLIKEKIKLSSGEIVKYIDGTNMGI
                     RFGIGIQGDMKEIFKTDVLREFPFPEIRGEKFCPEVLIWNRIGAKYKMRYFDKVIYLAE
                     YQEGGITAGITKARMNSPIASMMTYQEMTTYDIPLKWKIRSAINYWRFRQCLKKKDAEI
                     PKLSILWNIFMPIGWLMHNRDLKNVRR"
     CDS             2617..3660
                     /locus_tag="ctg3_1044"
                     /transl_table=11
                     /translation="MHITVDPRLKYNYASWYLLGLQQIGGSIEYNVMPFVGLSYKDTPD
                     YNSGFGFIIKEGNVTKKVFVDTEDVAKVFKDRYEWCDVYGMVNPTEEQVRQYDKLIPIG
                     PECGITLGSQLATVLKCVRLYLKGAKYTNIPFKTCLKDYLYTNIRRRPISDYENSIIVR
                     KNYIFHASTLWYNEFAATDTNKYRGEFLKACQRAGLEIEGGLFYVGGEAVLKEMPDYPK
                     YKEEYKDFIYDKRLSMDDYITKTKESVVVFNTPSVCGCHGWKLAEYLCMGKAIISTPLL
                     REMPAPMEHGKHIHFVHSVDEIYDAVVKINTDETYRKQLEEGARAYYEQWLAPEVVVKR
                     LIDKAKR"
     CDS             3662..4732
                     /locus_tag="ctg3_1045"
                     /transl_table=11
                     /translation="MKILQVITSMHIGGAEKVVMELILGLRTLGYDVDVALFSGEDTDF
                     KRQLDRSGCRVFSFSIGGKTYNPIYILKLWRIMHRYDIVHTHNTAPQFFAAIAGLGSKA
                     KLITTEHSSSNRRREKGHLKWFDNWLYGRYDTIVCIADQAKQAMETYLGRRMDDVAVIN
                     NGVNVEDFHSAEPASELYPHCGKFVIAMVAGFRYEKDQDTVIKAMTNLTDGYELWLVGD
                     GVRRKELETLIETEGVKDRVKLLGIRKDVSNILHAADVVIMSSHREGLSLSNIEGMSVG
                     KPFIASDVDGLREVTQNYGILFPHKDAIALAKIIDRLHTDKDYYHTVADRCYKRALEFD
                     VNKMVEGYIDIYRSLI"
     CDS             5435..5830
                     /locus_tag="ctg3_1046"
                     /transl_table=11
                     /translation="MSMLYPEISKLIVDAFYEVCRNLSVGYAEKVYEKALVYELQTLGL
                     QVEEQKPITVMYKGQLNVGSFIADIVVEDCIILELKATSMINKEHTAQLINYLICTGKD
                     VGYILNFGGDRRFERRLGPSALHSNAK"
     CDS             6234..7382
                     /locus_tag="ctg3_1047"
                     /transl_table=11
                     /translation="MNRKPKLLRVTTSDVSLDTLIKGQMKFLSSEFEVVGVSNNTGLLQ
                     KVAEREGIRVVEIPMHREISLVADVKCLWMLYRLFRKEKPEIVHANTPKGSLLSMVASW
                     AARIPNRVYTVTGLRYQGASGMFKALLMGMEKLTCRFATKVIPEGQGVLKALQEDHITN
                     KPLKVILNGNINGIDTTYFSKEAVGTSREDIRKALKLLPEDFTFIFVGRIVKDKGMNEL
                     AECMKLLAGKCKLILVGSFESEVDSLTEGKEAFLRTSEDVKFVGWQKDVRPYLAASDAL
                     VFPSYREGFPNVVMQAGAMGLPSIVTDINGCNEIIEDRTNGIIIPSRNQEALLNAMQYF
                     LTDKVAIQQMASCARKMIQDRYEQQQVWEALLAEYKNLLHKK"
     CDS             7384..7992
                     /locus_tag="ctg3_1048"
                     /transl_table=11
                     /translation="MYKHFFKRLIDFCIALFALVCISPILLVVTIWLHFANKGAGAFFF
                     QERPGKGGKIFKVIKYKTMTDERDAVGNLLPDEDRLTRVGKFVRSTSIDELPQFFNVLK
                     GDMSLIGPRPLLVQYLSLYSSEQARRHEVRPGISGWAQCHGRNAISWKQKFEYDVWYVD
                     HVSLFTDIKVIWLTLKSVFFREGISHEGSVTMEPFNGNN"
     CDS             7992..8663
                     /locus_tag="ctg3_1049"
                     /transl_table=11
                     /translation="MRKIAIFGAGGMGREVACIIRRINEVRNVPQWDFIGFYDDGIPAG
                     TQTDEGVVLGGIKELNEYNSPLNVVIAIGNPKVYKKIRDNLVNPKISYPNIIDPTVEFW
                     DINNYVIGEGNIICPHCTISCNVTIGNYNILNGDISLRHDVRIGSYNAIMPGVRISGGV
                     VMGNGVFIGLNAAVAQYLKVADNVRIGAGSILLSDTEADAFYTGVPAKKHTKEVETSGS
                     Y"
     CDS             8740..9762
                     /locus_tag="ctg3_1050"
                     /transl_table=11
                     /translation="MDWEGLYQFGKEQAILGILFKGIERLKDSAYKPSVAVIMKFYAYY
                     NEIVKLNRQVYQDANKLSLDFKEKYGINTCIMKGQANALMYPDPWVRQPGDIDVWTDAD
                     TVDVIKLARQLNPKAELGYHHIEIEFLRTPVELHFFPSFMGNLFYEWRLRTFFDSKKSL
                     QFQNKKALPDNLGSINCFTKDFDSVFQLSHLMHHFFFEGIGLRQMVDYFYLLKQGFTEE
                     EKRQIVEVIKRVNMFKFATGVMYIMKESLGLEDKYLLMQPNARIGKMLEKEIVLAGNFG
                     FYDTRFKFRGKSVYAQYLLELYRNLHFAIDFPSETVWGRPISRWWHMVYKAWLRYRARS
                     "
     CDS             10001..10417
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_1051"
                     /sec_met_domain="HBT (E-value: 2e-13, bitscore: 47.2,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDISNFWNNMRGDDGLTRSLGMEFICTPEPDTLQAKMLVCEKNKQ
                     PFGVLAGGASLSLAENLAGVGSMAACPGYIAMGINVNGSHVKAAFVGDVVTAYGKLLHK
                     GSTLHVWHVDVKNQNDELISTIQVTNYLVPNNKE"
     CDS             10449..11501
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_1052"
                     /sec_met_domain="Chorismate_bind (E-value: 2.3e-52,
                     bitscore: 174.8, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSFHELFLTHCASKGMFAVSRLPLADHCTFYYQESNPTEIYDLK
                     ALNGKQGFLFAPFIASKEHPILLMEKAEVTRCGLELSASLNDLKLSEVSNIADHYLYTF
                     NTFHTALKEKLFQKLVLARFVKVEVCEFDLEQLFLTACQLYPCQHIALVSSPQSGTWLM
                     ATPEILLEKQQGELWQTMALAGTMHKTEAEQEWSEKNKQEHEYVSTYILNCLAKYADTI
                     NVSDPYTAVAANLAHLRTDISFIPRNEQRIGDLLADLHPTPAVCGIPKEKAKEFIIANE
                     GMDRSYYSGFVGSLNMGGETHLYVSLRCMQIMKDSCRLYAGGGLLAESCVESEWKETEA
                     KLQTMRKLLL"
     CDS             11519..13192
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_1053"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-12, bitscore:
                     43.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSNKENVNILTSLLIAHDVQCAVLCPGSRNSPMVHNLVECNEMK
                     CYSVTDERSAGFVAIGIAEATDAPVVLCVTSGSALLNAAPAVAEAYYRNIPLIVVSADR
                     PQQWIGQSDGQTLQQVNALEPHVRKSVNIIEPHTEEERWYCNRVINEALNKVKAYGGGP
                     VHINIPLTEPLYEYTVAQLPDERYISFGSAMSNESELKDLITKLDKATKPVIVIGQLDA
                     GVAQTLSKDIAKIEQNYVVLQEKLSTAYGSTALQLDEMLAMIAGDEDYLPDFILYFGGT
                     IVSKRLKQYLRKAKTANSVLIDEHGEVRDVFMNLSWVIQAYPAMFVQLLAAHCKQRTTN
                     DYYQKWAELRKKASQHAENFCPDYSQMLAAKTFHTYLSRQRGKRALFYANSSSVRLGNI
                     YSKEYIHVNRGVNGIEGSLSVAVGYSLEASDNEQVYCVVGDLSFFYDNNALWNTYPKKN
                     LKVLLLNNGSGGIFHQMLGPSSSPYCNQYIAAGHQTSAEGICQSYGLKYQSAHSREDLS
                     QQMELFVKAHEGPLLLEVFTNADEDARVMNEYYRQLKEEK"
     CDS             13219..14097
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_1054"
                     /sec_met_domain="ECH_1 (E-value: 4.2e-81, bitscore: 268.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHLTLSPIAPLTPKKNMVQRNWKSIAGFNFEDILFEEFNHIAKI
                     TINRPRYRNAFTPRTVWEMSQAFNYCREALDIRVVILTGAGYKAFCSGGDMHVKGQGGY
                     VGNDGVPRLNVLDVQMQIRRLTKPVIAMVNGYAIGGGHVLHVMCDLSIASDNAIFGQTG
                     PRVGSFDAGFGASYLARIVGQKKAREIWFMCRQYNAVEAERMGLVNKVVAFDQLEDECV
                     AWAERMMEHSPLALRMIKAGLNAELDGQAGIQELAGDATMLYYTMEEAHEGGQAFLEKR
                     KPDFDKYPQFP"
     CDS             14172..15212
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_1055"
                     /sec_met_domain="MR_MLE_C (E-value: 4.1e-29, bitscore:
                     98.3, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCKINITSKLLHFKQPAGTSRGVYRTRKSYYVTVFDTAAPSVKGV
                     GECATLPDLSCDAMPDADYERLLRQFCNEVERTGKIDYEAMRPYPSMLFGLETALKQYE
                     RGGSLDFFDTPFGKGKEGIPINGLVWMGTFDEMFERLEEKLKAGFHCVKLKIGAIDFAK
                     ELELIKHIREAFTKDQIELRVDANGGFTSAEAMERLEALAKYDIHSIEQPIRQHQWRQM
                     ATLCQNTPLPIALDEELIGVNNLNEKQHLLDIIKPQYIILKPSLHGGMMGTREWIKLAN
                     ERNIGSWITSALESNVGLNAIAQLAADIYGSNIILPQGLGTGQLFTDNIPMPLEIRGEK
                     LYLIEN"
     CDS             15299..16306
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 73.7; E-value:
                     3.7e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_1056"
                     /sec_met_domain="AMP-binding (E-value: 1e-21, bitscore:
                     73.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLEEFLAEWNNSKPTVLVHTSGSTGKPKPLLIEKQRMLNSAKIT
                     CDFLGLKQGDKALLCMPLDFIAGKMMVVRGIERGMKIINVKPSGHPLSDEALRSANDDD
                     EITFAAMVPLQVANSLEVPKERERLLAIKHLIIGGGAVDDEMADTLKAFPNAVWSTYGM
                     TETLSHVALRRLSGKDASSWYEPFESVEIATTDDGCLVINAPLVCQAMLTTNDRVEISK
                     NVAGKTIFRVLGRKDNVINSGGVKIQIEEVEALLKPMLTKPYIITKRNDTKFGEVVVLL
                     TENENITEVETICKQILPKYWQPKLIKQVASIPMTATGKPARAQAFTIASNIEK"
     CDS             complement(16444..19140)
                     /locus_tag="ctg3_1057"
                     /transl_table=11
                     /translation="MKTKKRYAGLSDQEVLQSRAKHGANLLSPPAKDPLWKRFIAKFED
                     PLIIILLVAGVLSIGISFYEYFGLNEDMRVFFEPVGIFLAILLATGMAFFFEEKANKAF
                     SILNKVDDDEPVEVIRNGNTTKVPKKDIVVGDIVILNTGAEISADGKLLEAIALNVDES
                     TLTGEPICHKSIHTDDFDPDATFPTNYVLRGTKVMEGHGIFQVERVGDATENGKVFVAA
                     QIDNHVKTPLTEQLDRLGHLITVASYVIAALILIGRMAMYFLNFDFTWISFIQYFLATI
                     MICVTLIVVAVPEGLPMAVTLSLAYSMRRMLKTNNLVRKMHACETMGATTVICTDKTGT
                     LTQNQMQVHQMHVCGDSAEKLGIIMEGIAVNTTAELDLTDAQHPQALGNPTEGALLLWL
                     KAQNKDYRTLRKDAEVIDEVPFSTEHKYMATLVKSSFMSGKYVLYVKGATDIIRNKCKD
                     VMGNESWDTIRDQLLTWQNQAMRTLGFANYIINDNNPILQEKHPIEKLIGSFDGKENGL
                     TFLAIVAIADPVRHEVPAAIKECLNAGIDVKIVTGDTPGTAKEIGRQVGLWTDNANADK
                     HIITGTEFEQLTDTELLACVENLKIIARARPMDKKRLVEALQTRNQVVAVTGDGTNDAP
                     ALKAAHVGLSMGDGTSVAKEASDITIIDNSFKSIGRAVMWGRSLYQNIQRFILFQMTVN
                     VAACLIVLAGAFMGTQSPLTVTQMLWVNLIMDTFAAMALASLPPSEQVMKDAPRKRTAF
                     IIDKSMKQSILFMGGTFFVSLLAFLFILENYSVSHILDLIHFNDHTDKGMTAYELSAFF
                     TVFVMLQFWNMFNARAFHTGRSAFHLKDCKGFLFIAAFILIGQIAIVQLGGEMFNVTPL
                     SFIDWVLIILSTSFVLWFGEALRLIKK"
     CDS             complement(19172..20005)
                     /locus_tag="ctg3_1058"
                     /transl_table=11
                     /translation="MKDKQLVSNLLYAILFAGLFMLLQIGFTTLGAVAYSFAAHIDFAA
                     VMASLQTGENSILLSVTTALSSIATIILFLKRDWANVSNTYLKTHPWGVVIWAALLALG
                     SILPFEYIYERINISMPEHYQELFQNIMKEPWGYIVIGILAPITEELVFRGAILRALLK
                     GFGTYKHWVAIFVSALIFGLIHMNLAQGVHAFFLGLVLGWMYYRTDSIIPGIALHWVNN
                     TVAYLMFHLMPQMSDGKLIDFFHGSDRLMYGGLFFSLCIFIPSLFQLALRMKKAK"
     CDS             complement(20077..21033)
                     /locus_tag="ctg3_1059"
                     /transl_table=11
                     /translation="VNKLYLNKREQKHLTALVATIGFFDGVHRGHQFLIENVKRIAKQA
                     GMQSAVITFDLHPRQVLHPDQSPSLLSSLDQKLAHIEATGIDNCIVLHFDKALSQLSAK
                     EFMQTILKEQLNVQKLVIGYDNKFGHNRTEGFEDYQRYGKKLGIEVVENMALDTADEHI
                     SSSVVRKHIKNGEIKAANHDLGYIYTLEGKIVTGFQNGHKLGYPTANMDPKTCLQLLPA
                     DGVYAVKVKTDLSETWLDGMLYIGVRPTYNGNALCIETNIFNFDKELYGHNIKLALIDR
                     VRDDKKFESLEALSLQLGEDKLKCEEILKDESSKNHS"
     CDS             complement(21047..21670)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_1060"
                     /sec_met_domain="HAD_2 (E-value: 4.1e-11, bitscore: 39.9,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKQIKNIIFDLGAVLVNLDIECCVRAFEHIGAENVASMIKNHHL
                     TDLILDTELGNIDQQTFCNRVRLLVEKNLSDKDIIGAWNALLTGIPNKKKQRLLDLRKQ
                     YNIFLLSNTNYMHWQKCANDFFPYKGFGVKDYFNAIFLSYEMHLYKPNPDIFKEVLLQA
                     NIVANETLFVDDRVENCLAASKLGIHTYQNEHPDDWLTVEALSI"
     CDS             22229..23209
                     /locus_tag="ctg3_1061"
                     /transl_table=11
                     /translation="MKTTFKVSYYLRSNYENKEGKSPVMLRIYLGGEMANLGSTKIFVD
                     KSKWSNKTSRMIGRTADALSVNASIDAMTTTLMQIYRKYETSESLSLDLIRSVFLGTDK
                     EFTTFLPIFDKYIDAITQQVGKTLTKGTFYKYKVVRQNFQSFLQAKYHRKDIGLTELTS
                     AVVQDFELYLTSVVGGVHNTTTKKLRNLKTVVNYARNRGLIMHDPFANHKLRYELVDRG
                     YLTEEEVLRIMKKHFDIERLELVKNIFIFSCFTGLAYIDVYNLTYDKIVTVEDRQWLIT
                     KRYKTSVDENVMLLDIPLAIIRKYYDINRKGGKVFRKHPILAAFV"
     CDS             23244..23588
                     /locus_tag="ctg3_1062"
                     /transl_table=11
                     /translation="MFVLNETNVFRVCCTPVDMRQGILRLSQLVRSNDFNPSDGVVYVF
                     YNRSRNRIKLLHWERCGFVVYHKQMVQGCLSPKIIRARTGFYELRWDELVLYIEGINPN
                     CYRRKRYNKS"
ORIGIN
        1 aaatcttgtg aaccaagaag ataatctttt taatttatat gctattttgc cttgtgaaaa
       61 gatgttatta acatctatat atggttatga ttactttcag gggaacacac tctctacact
      121 gcataatagg agtattgaaa gtgttgaacg aaatgttaat gatactcttt tagcacaaaa
      181 agaaatacaa gagattatta gaagtatttc tgatgtagaa ttaaaaaagc gaatcataga
      241 acttttaaat cttaatgtag caggttttct cttttctatg tttcagacaa ggtatcctat
      301 agaaaagatt aaaatagcgt tagagcagct taaaaggatg cagttatacc caacacggtt
      361 tagttttaac agaaaatcaa atatcttcct ctgtggagca aacatagaat ggatttatct
      421 atgtttgtgt cgattacatg gagcaaaacg tttgtaatat acagaaaata gacacgtaga
      481 ctagaagaat aatattcttt tctactatag aaaaagtttg attttgataa aatattttta
      541 tgttgatata tatattagtt tttatagtag cctttattta ttacatacta tcaagaaaga
      601 attcttttct tagaaaatct tcagtagttc ttagcttttt cttcttgtat gtagctttat
      661 ttgtgggact tggagatatg ataggcggat acgatagata tatatatgga gaggtgtttg
      721 atacaattgc tgatgaattt caacatacga gttctcctaa tattaataag attatatacc
      781 ttgtgggagg taaagaatat ggttattttt tttggcagat attgctctca tatataactc
      841 aaaatcggta tatttttatt cttataacaa caattgccat ttatgtactt ttctttctag
      901 catttaagga atacctagat gactacccgt tagcgtgtat agtattctta gggttacttt
      961 attacttttc tatgacttat ctgaggcagg ttatcggagt cggttttaca tttttatcgg
     1021 taaagtatat cgttaaaaga aaattcttac ctttcttttg cttttggttg ttagcttata
     1081 gctttcatgg gtcagctctt attttctttc cgatgtattt tatacctcaa aaaaaatata
     1141 gtaaaaattt tgtaataaca gtcttgttac tttgcttgat agtaggtttg acccctcttc
     1201 ctaatgcttt actatctagt ggtgttacag catcagggaa agcgcaaaat tatatggatc
     1261 aagatcaagg gtttagaata gaatatgtta tagaagttgt tgcttttatt tcaattttct
     1321 ttatgaatta tggaaagata aacaaagaga aacaaacgct tgtgtttttg aatatgtctt
     1381 atgtattctg tgctcttctc ttactattta tgagatttgg gcaaggagga cgcttggggt
     1441 ggtattttat gccaggaatt atctatatga caacctattt gtgtaataga aaagatgttg
     1501 ctaagtggtt aaagcctgcg atgatattac tattttttgg actctttttt cgtattacct
     1561 tagcttggcg cgccttcaac gtaccctata aaacctttct tacgaatggt cagccagcag
     1621 gagatggcag tacttatgag aagtacgaat atgatgaaag gtacactatt gataaattct
     1681 tcagatgatg ataacggttt ttacacctac ttataatcgt ggaaatcttc ttaaacgatt
     1741 gtatgatagt ttatgtaatc aaagttttaa agattttgag tggttagttg ttgatgatgg
     1801 cagtaccgat aatacgggag aacttatgaa gcaaataatg acagacggta gtaataagtt
     1861 tgtcattagg tattttaaaa aagcgaatgg gggtaaacat tctgctatta attttggagt
     1921 gaaagaggct aaaggagaat tattttttat agtagactct gatgatattc ttcctccttt
     1981 tgccttgcaa gatgttattg atgtttggca caatatatat aataaggagc agtatgcagg
     2041 tgtttgtggt ttagatggat atttggagag tgaggtagtc atagggtcag gcttccctag
     2101 aaaattgatt aaggaaaaaa ttaaattgtc tagcggtgaa atagttaagt atattgatgg
     2161 aacgaatatg ggtattcgtt ttggtattgg tattcaaggt gatatgaagg aaatatttaa
     2221 gacggatgtt ctacgcgaat ttccttttcc tgaaatacga ggcgagaagt tttgtccaga
     2281 agtgcttata tggaatagaa ttggtgcaaa atataagatg cgttattttg acaaagttat
     2341 ttatttagca gaatatcaag agggggggat aactgctgga ataacaaagg caagaatgaa
     2401 tagccctata gcttctatga tgacttatca agagatgaca acgtatgata ttccgctaaa
     2461 gtggaaaatt cgttctgcaa ttaattattg gcgatttcgg caatgcttga aaaaaaaaga
     2521 tgcggaaatt cctaaactgt ctatactttg gaatatattt atgcctatag ggtggttaat
     2581 gcataaccgt gatcttaaaa atgtaaggag ataattatgc acattacagt agatccgcga
     2641 ttaaaataca attatgcttc ttggtatttg ctaggcttgc aacaaattgg cggtagtata
     2701 gaatataatg ttatgccttt tgtgggctta tcctataagg atacccctga ctataatagt
     2761 ggttttggct ttattataaa ggaaggcaat gttacaaaga aagtttttgt agatacggaa
     2821 gacgtagcga aggttttcaa agaccgttat gaatggtgcg atgtatatgg aatggtaaat
     2881 ccgacagagg aacaagttag gcagtatgat aaattgatac ctattggtcc agagtgtgga
     2941 attacattag gttctcaatt agctactgta ctaaagtgtg ttagacttta tttgaaagga
     3001 gcaaaatata caaatattcc ttttaaaact tgtctaaagg attatttata tacaaatatt
     3061 cgtcgtcgtc cgattagtga ttacgagaac tctatcattg tgcgtaaaaa ttatatcttc
     3121 catgcttcca cactttggta taatgagttt gctgcaacag acacgaataa atatcgtggc
     3181 gaatttctga aagcttgtca gcgagcagga cttgagatag aaggtggact tttttatgtc
     3241 ggaggtgaag cagtattgaa agaaatgcct gattatccta agtataaaga ggaatataag
     3301 gattttatct atgataagcg tctttcgatg gatgattaca taacgaagac aaaagaaagc
     3361 gtagtggtgt ttaatacacc tagtgtctgc ggctgtcatg gatggaaact ggctgaatat
     3421 ctatgtatgg gtaaggctat tatctctact ccgttgttaa gggaaatgcc agcaccaatg
     3481 gagcatggta agcatattca ttttgttcat tctgttgatg aaatttatga tgcagtggtg
     3541 aagataaaca ctgatgagac ttatcgtaag caactagaag agggagctag ggcatattat
     3601 gaacaatggt tagcaccaga agttgtggtg aaacggttga tagataaagc aaaaagataa
     3661 gatgaagatc ttacaggtta tcacctctat gcacattggt ggtgcggaaa aggtggttat
     3721 ggaattaatt cttgggctac gtacactcgg ttatgatgtg gatgtggcac tctttagtgg
     3781 agaggatacg gattttaagc ggcaattaga taggtctggt tgtagagtgt tttctttctc
     3841 tattggtggt aagacatata accctattta tatattgaag ttgtggagga ttatgcaccg
     3901 ttatgatatc gttcatacac ataatacagc cccacaattt tttgcagcga tagcaggttt
     3961 aggcagtaag gctaagttga taactacaga acatagttcg tcaaatcgta gacgtgaaaa
     4021 aggacatctt aaatggtttg ataattggtt gtatggacgc tatgacacga tagtatgtat
     4081 tgctgatcag gctaagcagg caatggagac ctatcttggg aggagaatgg atgatgtcgc
     4141 agtgataaac aatggtgtta acgtggagga ttttcatagt gctgaacctg catcggaact
     4201 atatcctcat tgtggtaagt ttgttatagc aatggtggca gggtttagat atgaaaagga
     4261 tcaagacacg gtgataaaag ctatgactaa cctgacagat ggatatgaac tatggttggt
     4321 aggcgatggt gttcggcgaa aggagttgga gacgttgata gagacagaag gtgtcaaaga
     4381 ccgtgtaaaa ctacttggta ttcgtaaaga tgtctctaat attttgcatg cagctgatgt
     4441 ggtgattatg tcttcccaca gagagggttt atcgttatcc aatattgaag gaatgagtgt
     4501 tggcaaacca tttatcgctt cagatgtgga tggactgcgt gaagtgacac agaattacgg
     4561 aatacttttc cctcataaag atgctatagc cctggctaag atcatagata gattgcatac
     4621 tgataaagac tattatcata cagtggctga tagatgttat aaacgtgcgc tagagtttga
     4681 tgtgaataag atggtagaag ggtacatcga catttatcgt tcgttaatat aaacatctac
     4741 tttccacgac aattgctttt aagtcgtgtt ctgttgtgta tgtcgttgct attatttcag
     4801 catcgacttt ccacgacttt tcacgacaat tgcttttaag tcgtgttcag tcgtgtatgt
     4861 cgttgcaatt attcagcatc tactttccac gacttttcat gacagtttct tttaggttgt
     4921 gttcagtcgt gtatgtcgtt gcaattattc agcatctact ttccacgact ttccacgaca
     4981 attgctttta agtcgtgttc agttgtgtat gtcgttgcaa tcattcagca tcggcttttc
     5041 acgactttcc acgacaattg cttttaagtc gtgttcagtt gtgtatgtcg ttgcaattat
     5101 tcagcatcta cttttcacga cttttcacga caattgcttt taagtcgtgt tcagttgtgt
     5161 atgttgttgc aatcattctg catcggtttt ccacgatttt ccacgacagt ttcttttgag
     5221 tcgtgccttg tcgtgtatgt cgttgctatt atttttgcat cgactttcca cgacttccca
     5281 cgacaattgc ttttaagtcg tgttcatttg tgtatgtcgt tgctattatt tttgcatcga
     5341 ctttccacga cttcccacga caattgcttt aggttgtgtt cagttgtgta tgttgttgcc
     5401 gaagtatagt attagcattt aatatttgtg cattatgagc atgctttatc ctgaaatatc
     5461 taagttaatt gtagatgctt tctatgaggt ctgccgaaat ctatcagtgg gttatgcaga
     5521 gaaagtttac gagaaagcac ttgtgtatga gttacagact cttggattac aagtggaaga
     5581 gcagaaacct attactgtta tgtataaagg acaactgaat gtaggctctt ttatcgctga
     5641 catcgttgtt gaagattgca tcatattaga gcttaaagcg acatcaatga ttaataaaga
     5701 acatacagca caacttatca actaccttat atgtacaggg aaggatgttg gttatatcct
     5761 aaactttggt ggagatagaa ggttcgagcg tcggttagga ccatcggcat tgcacagtaa
     5821 tgccaagtaa ggtcgtgcct tgtcgtgtat gtcgttgcta ttatttctgc atcgactttc
     5881 cacgactttc cacgacagtt gctttttggt tgtgttcagt tgtgtatgtc gttgctatta
     5941 tttttgcatc gactttccac gactttccac gatagtttct tttaggttgt gtttagttgt
     6001 gtatgtcgtt gcaattattc agcatcgact tttcacgact ttccacgaaa gtttctttta
     6061 ggttgtgttt agttgtgtat gtcgttgcaa ttattcagca tcgacttttc acgaaagttt
     6121 cttttgagtc gtgccttgtc gtgtatgtcg ttgcaatcat tcagtatcgg cttttcacga
     6181 catatttgct gataaataga attgtgtttg tcattgtcga aaaaataaaa tagatgaata
     6241 gaaaacccaa gttgctccgt gtgacgacat cagacgttag tctggatacg ctaatcaaag
     6301 gacaaatgaa gtttttgagc agtgagtttg aagttgtggg agtatcgaat aatacaggat
     6361 tgctgcagaa agtggctgaa cgagaaggga ttcgagttgt ggaaataccg atgcataggg
     6421 agatttctct tgtggcggat gttaagtgct tgtggatgct ttataggttg ttcaggaaag
     6481 aaaaaccaga gatcgtgcat gccaatacac ctaaggggag tttactctcg atggtagcta
     6541 gttgggctgc tcgtatacca aacagagttt atacggttac aggcttacgc tatcaaggcg
     6601 catctggaat gtttaaagcg ttgctaatgg gtatggaaaa acttacttgt aggtttgcta
     6661 caaaggtaat ccctgaagga cagggagtgc tgaaggcttt acaagaagat catattacga
     6721 ataagccgct gaaagtaata ctaaatggaa atatcaatgg tattgacact acttattttt
     6781 cgaaagaagc tgtaggaact agtcgggaag atataagaaa agctttaaaa cttttgccag
     6841 aggattttac ctttatattt gtaggacgta tagtaaaaga caaaggtatg aacgaattgg
     6901 ctgaatgtat gaagctgtta gcaggaaaat gtaaactaat tcttgttggt tcgttcgagt
     6961 cggaggttga ttcgcttacg gagggtaaag aagctttctt acgaacatct gaagatgtaa
     7021 agtttgtagg ttggcagaaa gatgttcgtc cctatcttgc tgcctccgat gctctcgtct
     7081 ttccaagtta tagagaaggt ttccctaatg tggtgatgca ggcaggggcg atggggttgc
     7141 catcaatagt tactgacatc aatgggtgta atgaaattat agaagatcgt acgaacggaa
     7201 ttattatacc ttcgagaaat caggaagcct tattgaacgc aatgcaatat ttccttacag
     7261 ataaagttgc tattcagcaa atggctagtt gtgctagaaa gatgatacaa gatagatatg
     7321 aacaacaaca agtgtgggag gctctattag cggaatacaa aaatttgttg cataaaaaat
     7381 aagatgtata agcatttctt taaacgacta atagattttt gtatagcatt gtttgcgctt
     7441 gtttgtatta gtccgatatt actagtagta actatttggt tacactttgc caataaggga
     7501 gctggtgcct ttttctttca agagcgccca ggaaaaggag gaaagatatt taaggtgata
     7561 aagtataaaa caatgaccga cgagcgcgat gcggtgggaa atctattgcc cgatgaggat
     7621 aggctgacta gggtaggaaa gtttgttcgc tcaacatcga tagacgagtt gccacagttt
     7681 tttaacgtgt tgaaaggcga tatgtcattg ataggaccac gtccgctttt ggtgcaatat
     7741 ctttctttgt attcctcaga acaagcacgt agacatgagg tgcgcccagg aatatctggt
     7801 tgggcacagt gtcatggcag gaatgctatc agttggaagc aaaaatttga atatgatgtg
     7861 tggtatgttg atcatgtgtc tctgtttaca gatattaaag ttatatggtt aacactaaag
     7921 tcggttttct tcagagaagg tatttcgcat gaggggagtg taacgatgga gccgttcaac
     7981 ggaaataatt aatgaggaag attgctattt ttggtgctgg aggaatggga cgtgaagtag
     8041 cttgtattat tcgaagaata aacgaggtgc gaaatgttcc acaatgggat ttcataggct
     8101 tctatgacga tgggataccc gcaggaactc aaactgatga gggcgttgtc ttaggcggta
     8161 taaaggaact gaatgaatat aattctccat tgaatgttgt cattgctatt gggaacccca
     8221 aagtgtataa aaagataaga gataatcttg ttaatcctaa aatatcatat ccgaatatca
     8281 ttgaccctac ggtagagttt tgggatataa ataactatgt tataggagaa ggtaacatta
     8341 tttgccctca ttgtactatc tcgtgtaatg taacgatagg taattacaat attttgaatg
     8401 gtgatatatc gttaagacat gatgttcgga taggtagtta caatgctatt atgcctggcg
     8461 taagaatttc aggtggagtg gttatgggca atggtgtttt tataggacta aatgctgctg
     8521 tggcgcaata tttgaaagta gctgataatg tgagaatagg tgcaggaagt attctcttga
     8581 gtgatacaga agcagatgct ttttatacgg gagttcctgc aaagaaacat acaaaggagg
     8641 tagagacaag tggaagttac taaacaaact ttattctatt ttgaatttat aaaatattgt
     8701 ctcaaagatg agcaagatat tccttctttt attaaagaaa tggattggga aggtttatat
     8761 cagtttggta aggagcaagc aatattaggt attcttttca aaggtataga gcgattgaag
     8821 gatagtgcct ataagcctag tgtggcagtt attatgaaat tttatgctta ttataatgag
     8881 atcgtaaaac taaataggca agtatatcag gatgctaata aattgtcgct cgactttaaa
     8941 gaaaaatatg gtatcaatac ctgcattatg aaggggcagg ctaacgctct gatgtatcct
     9001 gacccatggg tgcgacagcc aggagatata gatgtttgga cagatgcaga taccgtagat
     9061 gtcattaaat tagcacgaca acttaacccc aaagcagagt tgggctatca tcatatagaa
     9121 atagaatttc ttagaactcc tgtagagctt cacttctttc cctcctttat gggaaactta
     9181 ttttatgaat ggagattaag gacttttttt gactcaaaga aaagtctaca atttcagaat
     9241 aaaaaagcac tccctgataa tttgggaagc atcaattgtt ttacaaaaga ctttgacagt
     9301 gtttttcaat tgtctcattt aatgcatcat tttttctttg aaggtatagg gcttaggcaa
     9361 atggtagatt atttctatct actgaaacaa ggctttaccg aggaagagaa gagacagatc
     9421 gttgaggtga taaagcgggt aaatatgttt aaatttgcca caggagtgat gtatatcatg
     9481 aaggagagct tagggttgga ggataaatat ttattgatgc agcctaatgc gcgtataggt
     9541 aaaatgctag aaaaagaaat agtattagca ggaaactttg gattttatga tacgcgcttt
     9601 aaattcagag gaaaatcagt ctatgctcaa tatcttttag agttatatcg caatttacat
     9661 tttgcgattg attttccttc agaaacagta tggggaagac ccatctcaag gtggtggcat
     9721 atggtttata aggcgtggct tcggtatcgt gcaagatctt aggcaagtct taccaaactt
     9781 ttagacacag taacaacgca ttataaggct aacgctgtga aggatagaag aaagtcatgt
     9841 ttccatgcaa cgaagttttg cttctgagca tggaaacatg acttttttta tttgttaaag
     9901 ttggatttta ttagtaactt tgtatatctg ttatgattaa tttctagctg atggagttta
     9961 tgaaattagg cataatattt caatttttat agaaaaaact atggatattt caaatttctg
    10021 gaataatatg aggggtgatg atggactgac acgttcgctt ggaatggagt ttatctgcac
    10081 ccctgagcct gatacgttgc aagcaaagat gcttgtatgt gagaagaata aacaaccctt
    10141 tggagtatta gcgggtggag cttcattatc attggctgaa aatttggctg gtgtaggttc
    10201 tatggcggca tgtccaggct atattgctat gggtatcaat gtgaatggta gccatgtaaa
    10261 ggctgctttt gtgggtgatg tggttacggc atacggtaaa cttcttcata agggtagtac
    10321 tttgcatgtt tggcatgtgg atgtgaaaaa tcagaatgac gagctgattt ctactattca
    10381 ggtaaccaat tatcttgttc ctaataataa ggaataagga ttattttgat gcttaaatgt
    10441 aaacgataat gccttcattt cacgaattat ttttaaccca ttgcgcatcg aagggaatgt
    10501 ttgccgttag ccgattgccc cttgccgatc attgtacgtt ttattatcag gaaagcaatc
    10561 ccacagaaat atatgatctc aaagctttga acggtaagca agggtttctc tttgccccct
    10621 ttatagcgag taaagaacat cctatcttgt taatggaaaa ggcagaagta actagatgtg
    10681 ggctagaact ttctgcttct ttgaatgatt tgaaactatc ggaagtttca aacatagccg
    10741 atcattatct ttatactttt aatacctttc acacagcctt aaaggagaaa ctttttcaga
    10801 agcttgtttt agcacgcttc gttaaagtgg aagtatgcga gtttgacctt gaacagttgt
    10861 ttcttacggc atgccaattg tatccttgtc aacacatcgc tcttgtgagt tcaccacaga
    10921 gtggtacttg gttgatggct acgcctgaaa tattattaga aaaacaacaa ggcgaacttt
    10981 ggcaaacgat ggctttggct ggtacgatgc ataagacaga ggcagagcag gagtggtcgg
    11041 aaaagaataa acaagagcat gagtatgtgt ctacatatat cttgaattgt ttggcgaaat
    11101 atgccgatac gataaatgtg agcgatccct atactgctgt tgctgctaat ctcgctcatt
    11161 tgcgtacgga tatttctttt attcctcgca atgagcagcg cattggcgac ttgttagccg
    11221 atcttcatcc tacgccagca gtatgtggta ttccgaaaga aaaggcaaag gagtttatca
    11281 tcgcaaacga aggtatggat agaagttatt acagtggttt tgtgggatcg ctcaatatgg
    11341 gaggagaaac gcatctttat gtctcgcttc gttgtatgca gattatgaaa gatagctgta
    11401 gactatatgc tggaggaggg ctgctagcag aaagctgtgt ggaaagtgaa tggaaggaga
    11461 cagaagcaaa attgcaaacg atgcgtaagc ttttgctgta gaaaggaaga aataaacgat
    11521 gtatagtaat aaggaaaatg taaatatcct cacctcattg ctgatagccc acgacgtgca
    11581 gtgtgctgta ctttgtcctg gttcgcgtaa ctcgcccatg gtgcataatc ttgtggagtg
    11641 taacgaaatg aagtgttatt ccgttaccga tgagcgatcg gctggatttg tggcgattgg
    11701 tatagctgag gctaccgatg ctcccgtagt gttatgcgta acatcaggat cggcattgct
    11761 caatgcggct cctgccgtag ctgaggctta ttatcgcaat attccgttga tagtagtgtc
    11821 ggccgaccgt ccgcaacaat ggatagggca gagcgatggg caaacgctgc aacaggtaaa
    11881 tgcgctggaa ccacacgtga gaaaaagtgt gaatattatc gagccgcata cggaagaaga
    11941 acgatggtat tgcaatcgtg tgatcaatga ggctttgaat aaggtaaagg catacggtgg
    12001 cggtcctgtt catatcaata ttccgcttac agaaccgctt tatgaatata ctgtagcaca
    12061 acttcctgat gagcgttata tctcctttgg ctcggcaatg agtaatgaaa gtgagttaaa
    12121 agatttgatt acaaaacttg ataaagccac taaacccgta attgttattg gacagttgga
    12181 tgctggcgtt gctcaaactt tatctaaaga tatagcgaag atagagcaaa attatgtggt
    12241 attgcaagaa aaactttcaa cagcatacgg ttcaacagct ctacaactcg atgaaatgct
    12301 ggcgatgata gctggcgatg aggattatct gcccgacttt attctttatt ttggtggtac
    12361 aattgttagc aagcgtctaa agcaatactt acgtaaggca aagactgcta actccgtact
    12421 catagacgag catggcgagg tgcgagatgt gtttatgaac ctttcttggg ttattcaggc
    12481 ttaccctgct atgtttgttc agctacttgc ggctcattgc aaacagcgta cgacaaacga
    12541 ttattaccaa aagtgggcag aacttaggaa gaaagcatct caacatgcag aaaacttctg
    12601 tcctgattat tcccaaatgc ttgcagctaa gacctttcat acctatttaa gcagacagag
    12661 gggcaagcgt gcgttgtttt atgccaatag ctcatctgtg cgcttaggta atatctactc
    12721 taaggaatat atccatgtaa atcgtggtgt gaatggtatt gagggaagtt tatcggtggc
    12781 agtgggttat tcgcttgaag cttctgacaa tgaacaagtg tattgtgtgg taggcgacct
    12841 tagtttcttc tatgacaaca atgcgctttg gaacacttat cctaagaaaa atttaaaggt
    12901 gttgttgcta aacaatggta gtggtggtat cttccatcag atgctaggcc ctagcagttc
    12961 gccttattgt aatcagtata tcgctgcagg tcatcaaaca tcggcagaag gaatctgtca
    13021 atcatacgga ttgaaatacc aaagtgcgca tagtagggaa gatttatccc agcaaatgga
    13081 actgtttgtg aaagcgcatg aaggtccgtt actattagaa gtattcacca atgccgacga
    13141 agatgctcgt gtaatgaatg aatattaccg acagttgaaa gaagaaaaat aaataaaata
    13201 ataatttgag ttatagagat ggaacatttg acactatctc ctatagctcc tttaactcca
    13261 aaaaaaaaca tggtacaaag aaattggaaa tccattgcag ggttcaactt tgaggatatt
    13321 ctcttcgagg aatttaatca tatagcgaag ataacgatta atcgtcctcg ctatcgtaat
    13381 gcgtttactc cacgcacagt gtgggaaatg tcgcaagctt ttaattattg tcgtgaagca
    13441 ttggatatcc gtgtggttat tctgacaggt gctggctata aggctttctg ctcggggggt
    13501 gatatgcacg taaagggaca aggtggctat gttggcaatg atggtgtgcc tcgcttgaat
    13561 gtccttgatg tgcaaatgca gatacgccgc ttgacaaagc ctgtcattgc tatggtgaat
    13621 ggttatgcta taggtggggg gcatgtgctg catgtaatgt gcgacttgtc tatagcttcc
    13681 gataatgcta ttttcggaca gacggggcca cgtgtaggtt cgtttgatgc aggttttgga
    13741 gcttcctatt tggcgcgtat cgtaggacag aagaaagcac gcgagatatg gtttatgtgt
    13801 cgacaataca atgctgttga ggcagaacgg atgggattgg tgaataaagt agtggctttc
    13861 gatcagctag aagatgagtg tgtggcatgg gcagagcgta tgatggaaca ttctccattg
    13921 gctcttcgta tgataaaggc tggcttgaat gccgaactag acggtcaggc tggtatccaa
    13981 gaacttgctg gcgatgctac aatgctttat tatactatgg aagaagctca cgaaggggga
    14041 caagccttcc ttgaaaagcg taagcccgac tttgataaat atccacagtt cccataagag
    14101 acagtgtggc tgtcgtttct tttatgttac tctgttactt tgtcttataa attgtcttta
    14161 ataggaaagt tatgtgtaaa attaatatta catcaaagct tttacacttt aagcagcctg
    14221 ctggaacttc gagaggtgtg tatagaacga ggaagagtta ctatgttacg gtgtttgata
    14281 cggctgctcc tagtgtgaaa ggtgttggcg aatgtgctac attgcctgat ctgtcgtgtg
    14341 atgctatgcc agatgcagat tatgaacgat tattacgtca gttctgtaat gaagtagaac
    14401 ggacaggaaa gatagattat gaggctatgc gaccttatcc ttccatgctt ttcggactag
    14461 aaacagcact gaagcaatat gaaagaggag gtagtttgga tttctttgat actccttttg
    14521 ggaaagggaa agaaggtatt cccattaacg gtcttgtatg gatgggtact tttgatgaga
    14581 tgttcgagcg gcttgaggag aagctcaagg ctggatttca ttgtgtaaaa ctaaagattg
    14641 gtgctattga ttttgccaaa gagttggagc ttatcaagca tatccgtgaa gcatttacca
    14701 aagatcagat agaactccgt gtagatgcta atggtggttt tacatcagca gaggcaatgg
    14761 aaagattaga ggctttggct aaatatgata ttcattcgat agagcagcct atcaggcaac
    14821 atcaatggcg gcagatggct acactttgcc aaaacacacc attgcccatt gcgctagatg
    14881 aagaactcat aggggtaaat aatctcaatg agaaacaaca tttattagat atcattaagc
    14941 cacaatatat cattcttaaa cctagcttac atggaggaat gatgggtaca cgtgaatgga
    15001 ttaagctagc caatgagcgc aacattggct catggattac ttctgcccta gagagcaatg
    15061 taggcttaaa tgctattgca cagttggctg cggatattta tggatctaac attatcctac
    15121 cacaaggtct aggcacaggg caattattta cggataatat cccaatgcca ttggagataa
    15181 gaggggaaaa actttatcta attgagaatt gagagttgag aattgagaat tgagagttgc
    15241 ccgcctaatg tgttatctaa ttgataattg cttatcaatg tctaaaaaaa taaaaccaat
    15301 gactttagaa gaatttcttg ccgaatggaa taatagcaaa cctacggttc ttgttcatac
    15361 tagtggatca acaggaaagc ctaaaccact gcttatagag aagcaacgta tgctcaactc
    15421 tgcaaagata acttgcgatt ttttgggttt aaagcaagga gataaggctc ttctgtgtat
    15481 gccactcgac tttattgctg gtaagatgat ggtggtgcga ggtatagaac gtggtatgaa
    15541 aattatcaat gtgaagcctt ctgggcatcc actatccgac gaagcgttga gaagtgcaaa
    15601 cgatgacgat gagataactt ttgcagcaat ggttcctttg caagttgcaa attcgttgga
    15661 agttcccaaa gagcgtgaac gtttgcttgc tattaaacat ttaattattg gtgggggagc
    15721 ggtagatgat gaaatggcag atactttaaa agcttttcca aatgctgtgt ggagtacata
    15781 cggtatgaca gaaacgttat cgcatgtggc gttacgtcgc cttagtggaa aggatgctag
    15841 cagttggtat gaacctttcg aaagtgtcga aatagctaca acagatgatg gatgtcttgt
    15901 gatcaatgct cctttagtat gtcaggcgat gctaacaacg aacgatagag tggaaattag
    15961 taagaatgta gcaggaaaaa ctattttccg tgtgcttggg cgcaaagata atgtgattaa
    16021 ctcgggagga gtaaaaatac aaatagaaga ggtggaggca cttctcaaac caatgcttac
    16081 aaagccttat attatcacta agcgcaatga tacgaagttt ggagaggtgg ttgtactgct
    16141 aacagagaat gaaaatataa cagaagtaga aactatatgt aaacaaatat taccaaaata
    16201 ttggcaaccc aaactcatta agcaagtggc ttctatacct atgacagcta cggggaaacc
    16261 tgctcgtgct caggctttta cgattgcttc aaatatagaa aaataaaagg taagcttttg
    16321 ctctctaaaa gcttaccttt tacgtggtaa aagatgacct attacagagc aaaaggtcat
    16381 ctttttaaac ggacaagatc atctatcggt tttacataga tcatcttgtc cgtttttttt
    16441 gttttacttc ttaatcaacc taagtgcttc accaaaccat aaaacgaagg aggtactaag
    16501 aatgatgagt acccaatcga taaagctgag cggagtaaca ttgaacattt caccgccaag
    16561 ttgcacaatg gctatttgtc ctatgaggat aaaggctgct ataaatagga agcctttaca
    16621 atcttttaag tggaaagcac ttcgccctgt atggaaagca cgtgcattaa acatattcca
    16681 aaattggagc ataacaaaaa cagtgaagaa agcgctaagt tcgtaagccg tcattccctt
    16741 atctgtatgg tcgttgaaat ggattaaatc gaggatatgt gatacagaat agttttccaa
    16801 gataaacaag aaagcgagta gggacacgaa gaaggtacct cccataaaga gaatgctctg
    16861 cttcatagac ttatcaatga taaaggctgt gcgcttgcgt ggagcatctt tcattacttg
    16921 ttctgagggt ggtaatgaag ctagagccat agcagcaaag gtatccataa tgaggtttac
    16981 ccatagcatt tgtgttaccg ttagcggact ttgtgtaccc ataaatgcac ctgccaatac
    17041 gataagacat gcagctacgt tcactgtcat ttggaatagg ataaagcgtt gaatgttctg
    17101 atacaatgag cgtccccaca ttactgctcg gccaattgat ttaaacgagt tgtcgataat
    17161 tgtaatgtcg gatgcttctt ttgccacact cgtaccgtcg cccattgaaa gccctacgtg
    17221 tgcagccttt aatgctggtg catcgttggt gccatcgccc gtaacggcta ctacctgatt
    17281 gcgtgtttga agggcttcta ctaatctttt tttatccatt gggcgggcac gcgcaatgat
    17341 tttcaagttt tctacgcatg ctagtagctc tgtgtcagtg agctgttcaa actcagtacc
    17401 tgtgataatg tgcttgtctg cattagcatt atctgtccat aatcccactt gtcgtcctat
    17461 ttcctttgct gttcccggag tatctcctgt aacgatctta acatcaatgc ctgcgttgag
    17521 acactcctta atagcggcag gtacctcatg gcgaacagga tcggcaatgg ctacaatggc
    17581 aagaaaggtg agcccatttt cttttccatc aaagctacct atgagttttt ctatagggtg
    17641 cttctcttga agaatagggt tgttatcgtt gatgatatag ttagcaaaac caagggtgcg
    17701 catagcttgg ttttgccatg taagtagttg atcgcgaata gtatcccacg actcgttgcc
    17761 cattacatct ttgcatttat tgcggataat atctgttgca cctttcacat aaagtacata
    17821 tttcccagac ataaagctcg acttcacgag tgtagccata tatttgtgtt cggtagagaa
    17881 aggtacttcg tctattactt cagcatcctt tctcaaagtg cgataatcct tattttgagc
    17941 tttcaaccac aatagaagtg cgccttctgt agggttgcca agggcttgag gatgttgagc
    18001 atctgtaaga tctagctctg cagtagtatt tacagcaatg ccttccatta tgataccgag
    18061 tttttctgca ctatcgccac atacgtgcat ctggtgtact tgcatctgat tttgtgtcag
    18121 tgtacctgtc ttatctgtgc aaataacagt agtagccccc attgtttcac atgcgtgcat
    18181 cttgcgtaca agattattgg ttttgagcat tcggcgcata gagtaagcca aactcaaggt
    18241 aacagccatt ggcaagcctt caggtacagc tacaacaata agtgtaacgc agatcattat
    18301 agtggcgagg aagtattgaa tgaatgatat ccaagtgaaa tcaaagttta gaaagtacat
    18361 tgccattcgt ccaataagga ttagagcggc aataacataa ctagctacgg ttataagatg
    18421 acctaatcgg tcgagctgtt ccgtgagggg agttttcaca tggttatcaa tctgtgccgc
    18481 tacgaaaacc ttaccatttt cggtagcatc gcccacacgt tccacttgga agatgccgtg
    18541 tccttccatt acctttgtac ctcttagtac ataattggta gggaaagtag catctggatc
    18601 gaagtcgtca gtgtggatac tcttatggca aattggttcg ccagtaaggg ttgattcgtc
    18661 cacatttagt gcgatagcct caaggagctt gccatcggca gagatttcag cacctgtatt
    18721 aagtataaca atatcgccca ccacaatgtc tttcttaggc actttggtgg tattaccatt
    18781 acggataacc tctactggtt cgtcgtcgtc caccttattt aatatagaga aagccttatt
    18841 tgctttctcc tcaaagaaga aagccatacc tgtggcaagg agaatagcca agaaaatgcc
    18901 cactggttcg aagaaaacac gcatatcttc gtttagtccg aagtattcat aaaaggaaat
    18961 acctatggat aaaacaccag caacgagaag aataatgatg agcgggtctt caaacttagc
    19021 tataaatcgt ttccaaagcg gatcttttgc aggcggagaa aggaggttgg ctccatgttt
    19081 cgctcggctt tgaagtactt cttgatcact aagtccggca tatctttttt ttgttttcat
    19141 tgatgttttt gtattgctat tgttgtattt tttattttgc tttcttcatg cgtagagcaa
    19201 gttggaagag cgaagggata aagatgcaga gcgagaaaaa tagtccgcca tacatcagcc
    19261 tgtcgctacc gtggaaaaag tcgatgagtt tgccatctga catttgtggc ataaggtgga
    19321 acatcagata agccacggta ttgttaaccc agtggagcgc aatgccagga ataatactat
    19381 ccgtgcgata atacatccat ccgagtacta aaccaaggaa gaaggcatga accccttgcg
    19441 caaggttcat gtggataagc ccgaagatga gggcagaaac gaagatagcc acccagtgtt
    19501 tataggttcc aaagcctttt aataatgcac gtaagatagc tcctcgaaaa actagttctt
    19561 ctgtgatagg tgctaaaata ccaataacaa tatatcccca tggctctttc ataatgtttt
    19621 gaaacagctc ttgataatgt tcgggcatcg aaatgttgat gcgttcgtaa atgtattcaa
    19681 agggtaggat agagccgagg gctagtaatg ctgcccatat tactactccc caaggatgcg
    19741 ttttaagata tgtattagat acgtttgccc aatctctttt tagaaaaagg ataatcgtgg
    19801 caatactgct aagagcagtt gttacgctga gcaagatact attttcgcca gtctgaagcg
    19861 atgccatgac ggcagcaaag tcaatatgtg cggcaaagga atatgccacc gcaccaagtg
    19921 tggtgaaacc tatttgcaaa agcataaaaa gacctgcaaa aaggatagcg taaaggaggt
    19981 tggatacgag ttgtttatct ttcattttac gaattaataa atctctattt ttttatgaat
    20041 gaatttcaaa ttatttatga atgaaattcc gatggtttat gaatgatttt ttgaagactc
    20101 atcttttaat atttcttcgc acttcaattt atcttcgccc aattgtaggg aaagtgcttc
    20161 taaggactca aatttcttat cgtctcgtac tcggtcgatg agtgctagtt tgatattatg
    20221 tccataaagc tccttgtcaa agttgaatat attagtttcg atgcaaagcg cattaccgtt
    20281 atatgtaggg cgaacaccaa tgtagagcat accatcgagc cacgtttctg acagatctgt
    20341 tttcactttc actgcataaa caccatcggc aggtaggagt tgaaggcatg tcttaggatc
    20401 catatttgct gtggggtaac ctagcttatg cccattttgg aaacctgtaa cgatctttcc
    20461 ctctagcgta tatatatagc ctaggtcgtg attagctgct ttaatttcac catttttgat
    20521 atgtttgcgc accactgatg aacttatatg ctcgtctgcg gtgtctaacg ccatgttttc
    20581 tacaacttct atgccaagct ttttcccata acgttgataa tcttcaaagc cttccgtacg
    20641 gttatgtcca aacttattgt catagcctat gacgagtttt tgcacattaa gttgttcttt
    20701 cagaatagtt tgcataaact cttttgccga aagctgtgat aaagctttgt cgaaatgaag
    20761 tacaatgcaa ttgtctatac ctgtcgcttc gatgtgtgcg agcttttgat cgagcgatga
    20821 aagtagggac ggcgactgat cgggatgcaa cacttggcgt ggatgcaaat cgaaagtgat
    20881 cacagccgat tgcatacctg cttgttttgc aatccgtttt acattctcaa ttaagaactg
    20941 atgaccacga tgcacaccat cgaagaaacc gattgtggca accaaagcgg taaggtgctt
    21001 ttgttctctt ttatttaaat atagcttatt cactatgctt actgttttat attgataacg
    21061 cttccactgt caaccaatca tcaggatgtt cattttggta agtatgaatg ccgagtttgc
    21121 ttgccgctag gcaattttca actctgtcgt caacaaataa tgtctcgtta gcaacaatgt
    21181 tagcttgtag caaaacttct ttaaaaatat cgggattagg tttgtaaagg tgcatctcat
    21241 aagagagaaa aatggcattg aaatagtctt tcacgccaaa tcctttataa ggaaagaagt
    21301 cgttcgcaca tttttgccag tgcatataat tagtgttgga aagaaggaag atattatatt
    21361 gtttgcgcaa atcgagcaac cgctgtttct ttttgttggg tattccagtc agcaaagcat
    21421 tccaagcccc aataatatct ttgtcagaaa gattcttttc gacaaggagg cgtacacgat
    21481 tgcaaaacgt ttgttgatcg atatttccga gttcagtatc tagtattagg tcagtaaggt
    21541 ggtgattctt tatcattgaa gccacattct ctgctccaat atgctcaaag gcacggacac
    21601 aacattctat atcgagattg acaagtactg caccaaggtc gaaaataata ttcttaattt
    21661 gtttttgcat tgtttttgcc ttataaagta ttaggaatat cctcgtgcaa agatacataa
    21721 aagcacccta acctagggct tctgcacctc aaatagtgtt aaaacgtaaa aaaaataggc
    21781 tttacctata cgctatttcc tttttattta ttatctttgc atccgaattt caatgaattc
    21841 tcggacttgt agctcagttg gttagagcaa cagactcata atctggaggt ccctggttca
    21901 agcccaggct ggtccacaaa gaggtttcaa gaggatgtca aacaacacgt cattttagcc
    21961 ttcaaaacaa ggataatcgc tgtaaaatca aggttttaca gcgatttttt gttttttatc
    22021 catattcgtt tgactgccaa accatacctt ttgatagtca tcattcggtc attttctgct
    22081 acagaaactg ctacacaaaa gcaggctcgc aaaaaaatgt agcagtgaat ggaaaatgac
    22141 taccaaattg acggcataca aatatctcgt tttcaacaat ttatgtcgaa ctttgtagcc
    22201 aagaaagcta cactaaaaat gatgcgttat gaaaacgact ttcaaggtgt cctactacct
    22261 acgttccaac tacgagaaca aagaaggaaa atcgcctgta atgctccgaa tttatctcgg
    22321 aggcgaaatg gctaatcttg gatccactaa aattttcgtg gacaaatcta aatggagcaa
    22381 caaaaccagc agaatgattg gtagaacggc agatgctctc tccgtcaatg catcaataga
    22441 tgcaatgaca acaactttga tgcagatcta taggaaatat gaaacctctg aaagcttgtc
    22501 cttagatctt atcaggtcag tgtttcttgg aacagataag gaatttacaa cttttctccc
    22561 tatctttgat aaatatattg acgccattac gcaacaagtt ggtaagacac tgacaaaggg
    22621 gacgttttat aagtacaagg tggtgaggca gaactttcaa agcttcctac aagcaaagta
    22681 tcatcgtaag gatattggac tgacagaact gacaagtgcc gttgttcagg acttcgaatt
    22741 ataccttaca tccgttgtag gtggtgtaca taacacaacc accaagaaat tgagaaacct
    22801 gaaaacggtc gtgaactatg cgaggaacag aggacttatc atgcatgatc catttgcgaa
    22861 tcacaagctg cgctatgaat tggtagatcg tggctacctc acagaagaag aggtactccg
    22921 tattatgaag aagcactttg acatagaacg gctggagtta gtaaagaata tttttatttt
    22981 ttcctgcttt acaggattag cctacattga cgtatataat cttacctacg ataagattgt
    23041 tactgtcgaa gacagacagt ggcttatcac caagaggtat aagacaagcg tagatgaaaa
    23101 tgtcatgctg ctggatattc cccttgccat cataagaaag tattatgaca ttaacagaaa
    23161 aggtggaaag gtatttcgta agcatccaat attagccgcc tttgtgtagc attcttgctt
    23221 tactaccttt gcccgaaaaa cttatgtttg tactcaacga aacaaatgtt tttcgggttt
    23281 gttgcactcc tgtggatatg cgtcagggta ttcttcgcct gtcccaattg gtacgtagca
    23341 atgacttcaa tccttctgat ggtgttgtct acgttttcta caatcgatcc cgtaaccgaa
    23401 tcaaattgct gcactgggaa cgctgtggtt ttgtcgtcta tcataaacag atggtacagg
    23461 gttgcctgag tcctaaaatc atacgggcga gaactggatt ttatgaactt cgctgggacg
    23521 aactggtact ctatattgaa ggtataaatc ctaattgcta ccgaagaaaa agatacaaca
    23581 aatcttagta ttttcttgcc agtgtcagat atttttcgca cctttacatt gtataaagaa
    23641 ctgataatgt aatggatatg ccttattgca caatgacatc tgactaccat tctctcactc
    23701 gggaagctgt tgttaaactt cttgagcaaa gggatgctga gcttaaggtt aaggatgctg
    23761 agctggaaca aaagtcccgt cgtattcttg aacttgagcg catggtattt ggcaggcgca
    23821 gcgagaaacg cctgcctgag agtgcaagcg actggacggg tacgcttttt gacgagcagt
    23881 gggccaaaga gggttctctg gctcgggtag aagcccttcc catcatcaag gagataaaac
    23941 agcagtccgg acaacgcagg tcatcacgcc gtgtgagccg cccttccaga aagggtacgg
    24001 cctacgcctc ctatgttccc gagaacatag agcgacaggt gacggagata tacccagagg
    24061 attatgatgc tgagcgcatg gctatcatcg gacatga
//
