LOCUS       NZ_DS499579.1          15320 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_DS499579.1 Alistipes putredinis DSM 17216 Scfld_02_9, whole
            genome shotgun sequence.
ACCESSION   NZ_DS499579
VERSION     NZ_DS499579.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:19:52
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15320
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15320
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4000:5320](-)"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(4001..5320)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..15320
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15320
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             1361..2560
                     /locus_tag="ctg3_1"
                     /transl_table=11
                     /translation="MKKIFCLVCFFLALFSLKSIADVPEGAIPFVFDGHLYLQSTLNDT
                     IPVTLIYDTGADFLYLDEDYLKLNHLQNAFGRKGKATMGGAGNGEPERIDIFIDPITVH
                     CGAREYQNEITPIIKLRDLLGRHTDGLLGNTHLLMNPLEINFSESYLRQLKGPLLAEQL
                     DNYVKLDARFEDNRIDVKATLQIDDENSLEGWFRMDLGCGSTIILTNETASAFNFMDVP
                     KAYFCTQAGGIGGGSEEVTIRAAKFFMADTLENLVIDYSLNEKGALSSDRPYIGIIGNE
                     IWSLYDIVLDPVSSSVWVKRNENQGTYAQSSVTHMATVDRTDICGGWIVNGLYKGGVAE
                     QAGIEIGDIIVAINNRPVKEITWEEQRKGLELQGETTYTVQKPDGQIVSYTLFIGKQII
                     "
     CDS             2775..3413
                     /locus_tag="ctg3_2"
                     /transl_table=11
                     /translation="MKHPVDIDNWNRRENYLFFRDFANPYYSVTSQVDVTEAYIRAKAL
                     GIKFSHYAMYASLRAVNSIEALRYRQVDGKVWLYDRIRLNTAVAREDHSFASVIIPYND
                     TLEEFVAEARGIIAAAMRGEGDAYGADSEKDTFVISVNPWYSFTGLQFQFPQNAGENIP
                     LSVFGKIMVDMQGRRTMPVAVSFHHGFVDGYQVGRYWEAFQHNLDTLSM"
     CDS             complement(4001..5320)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hydro"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hyd_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_3"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 5.6e-59,
                     bitscore: 193.6, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 4e-27, bitscore:
                     90.6, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTQIKFTTAAEAVKVIKSGDHIHLSSVASAPQCLIKAMCERGAN
                     HEFKDVHIHHLHTEGPAPYADPQFEGIFQLDSFFVGGNVRKVTQSGYADYIPIFLSETQ
                     KLYRSGTVPCDVAMIQVSTPDKHGYVSLGTSVDATLAAVETARTVIAVVNKHVPRSFGD
                     AMIHSSKIDLFVQDDTPLEEAHFTEPNEIETRIGKHCAALIEDGATLQMGIGAIPNAVL
                     AQLGNHKNLGIHTEMFADGVLPLVEKGVINGEAKNIDKGKMVSTFLMGSQRVYDFIDDN
                     PGVLMMDVGYTNDPFIIAKNDRVTAINSALQVDITGQVCADSLGTKFYSGVGGQIDFIY
                     GASLSKGGKAIIAMPSVTNKGISKIAPELTCGAGVVTTRNHIHWFVTENGAVNLYGKSL
                     QERARLIISIADPSAQESLDRAAFERYGQHHHYVKNYMGK"
     CDS             complement(5360..8086)
                     /locus_tag="ctg3_4"
                     /transl_table=11
                     /translation="MSNERKLRLIQVAKEFKVGLNTITDFLQKKGIKTDGSPNTLVEPD
                     VYAVLEKEFGGSRITGNERESIRERISQKQATITLEEAQKQTREEEQEVIIKSNVISVK
                     DELPQPKILGKIDLSPKPKPAPKPVSKPAAEPVPEAAAPKPQPAPQPAAPKTEAAPASE
                     TASAAKPEPEAAPKSDNIFRPAVQTLTGPQVLGTMDVSGFTPGNRHKRKRLSKEKVDVT
                     RTPAGSPKPGSNGKSAAQPGRGQGPQSNQPRPGENKKTRKDKLKAPKPVVRPEISDEEV
                     SKQVKDTLARLTSKNAKSKGSKYRKEKREAVAERMNEEFQREEQERSILKVTEFVTVAE
                     LATMMNVSATEVITACMNLGLMVSINQRLDAEALVVVAEEFGFKTEFVSADIQEAIGDD
                     EQDSEEDLVPRPPIVTVMGHVDHGKTSLLDNIRKTNVIEGEAGGITQHIGAYSVELNGQ
                     KITFLDTPGHEAFTAMRARGAKITDVAIIIVAADDNVMPQTVEAINHAQAAGVPMVFAI
                     NKIDKPAANPDHIKEQLSQMNYLVESWGGKYQDQEVSAKKGLNLDKLLEKVLLEAEMLD
                     LKANPNRRASGAVIESTLDKGRGYVATVLVQNGTLHIGDVMLSGIHTGRVKAMFNENGQ
                     KVTEAGPSTPVQVLGLNGAPQAGDTFNVMEDDRSAREIANKREQLQRIQGIMTQKHVTL
                     DEIGRRIAIGSFKELNIIVKGDVDGSVEAMSGSLIKLSKETVQVNVIHSAVGQISESDV
                     LLAAASNAIIVGFQVRPSASARKLAEKEEIEIRLYSIIYDAINDIKDAIEGMLEPVMKE
                     EIVCSAEVMEIFRISKVGTVAGCVVREGKLTRHTPIRVIRDGIVIYTGKLGSLKRFKDD
                     VKEVLTGQDCGLNIESFNDIRVGDVIEGYEQVEVKRN"
     CDS             complement(8120..9352)
                     /locus_tag="ctg3_5"
                     /transl_table=11
                     /translation="MDNLNLISNFAEFKELKNIDKATMIGVLEDVFRHALQKQFETDEN
                     FDVIINPEKGDLEIWRNRTVVEDGAVENPNMQIAVSEVKAIDPTYEVGDEYVDPIKLES
                     FGRRAVLSLRQNLASRILDLEKANLYEKYSEKVGEIITGEVYQVWKKEVLILDDEGNEL
                     ILPKTEQIPNDYYRKGDTIKAIVKSVEMNNNQPRIILSRTANQFLERLFEQEVPEIFDG
                     LITLKKIVRIPGERAKVAVESYDERIDPVGACVGMKGSRIYSIVKELRNENIDVVNYTT
                     NPQLMIQRALNPAKISSITIDEEKKTASVYLKPDQVSLAIGKGGLNIRLSKMLTGYDID
                     VYREIEEEDVALTEFADEIDGWVIDALKACGCDTAKSVLELPVEEIAARADLELEQAQK
                     VVEILKAEFEE"
     CDS             complement(9386..9853)
                     /locus_tag="ctg3_6"
                     /transl_table=11
                     /translation="MIDCTKITEIANAKLVGTDLFVVDCTCSPANEVELLIDSDTSVGI
                     ETCVELSRAIEAEFDRDTEDFSLTVASAGIGSELKHLRQYRKLIGKPVEVLLKSGVKIL
                     ATLDEADQEGLTLSYEEKQAVEGKKRKQTVRVTRRYPFSEIKYTKEYLDFK"
     CDS             complement(10337..11137)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hexapep"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_7"
                     /sec_met_domain="Hexapep (E-value: 7.9e-11, bitscore: 36.5,
                     seeds: 216, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISNQAYIHPDAKLGKNVTVEPFAYIAGDVVIGDDCWIGPGAVIH
                     DGARIGKGCKIHTAASIACTPQDLKFVGEKTTAEIGDYNEIRECVTISRGTASRGKTVV
                     GSHNLIMAYVHIAHDDVVGSHCVMANRVSLAGEVEVGDWAVIGGHVAVHQWTRIGEHTM
                     IQGGALVGKDIPPFITVSNNDPVRFACVNRVGLSRRGFTPETISQIHDACRILFQSGLN
                     YLNGCEEVEKQIPQSPERDRLIRFIRESQRGIIKPYSQSNEKDE"
     CDS             complement(11144..12535)
                     /locus_tag="ctg3_8"
                     /transl_table=11
                     /translation="MAAKQQTLKAPISFSGTGLHTGVKVTMTVHPAPENSGIVFRRIDL
                     EGKPEIPALCDYVTDTSRGTTIEKDGARVATIEHIMSALWTLGVDNATIDVDAGETPIM
                     DGSAKEYAKTIVETGLQPQEAERTYYHVTEKMVYTIPEKGVAIILYPDDEFSVSLHVDY
                     NSKVIGNQYATFDPEDDYAAKIAPCRTFVFLHDLEPLMKMNLIKGGDLDNAIVVVENPV
                     PDDQLEHLKKIFNKQDIRITGGYLNNLELRFNNELARHKLLDLLGDFALLGKRIKGRVW
                     ATRPGHFANTEFMKQVKRTIRREGEKPRFQYDCRKPPVYDINDIRRMLPHRPPFLLVDR
                     IFYIDDTTVAGIKNVTMNEPFFVGHFPEEPVMPGVLIVEAMAQCCGMLVLRSIPDPEHY
                     STYFMKIDGVKFKRKVVPGDTLHFEVQLLEPIRRGVAVVEGKAFVGETLACEATMMAQI
                     VKNKE"
     CDS             12707..13501
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="VASPDRTPRPPKLQLPFEQKKNDAGEWAYDHRIGLCVTLIAYLVL
                     AIAFMVGKIVVGAKPSVQGIIIDTKTLAELEAEKMRLEQEVRARQQAQEGGDWRDVRNQ
                     YSNENALEERSRDDRGSMSSSLKESAEAVGERMQANRDAYEQGLAEERAIRERMGRSGK
                     DDRTQDSRARGRVTVSFSLTDPVRTRRYLEVPAYQCEGGGEVVVGITVNPSGEVVAAKV
                     ASGGDDCMREAALEAARNSLFNIDDSAPARQSGTITYLFIPQ"
     CDS             13567..15063
                     /locus_tag="ctg3_10"
                     /transl_table=11
                     /translation="MHNIITTENILLIGALLLFVAVMAGKAAYRFGAPALLFFLGVGML
                     FGINFISFHSVEATQFVGMIALCIILFTGGMDTKFSEIRPVIGPGIVLATAGVVMTAVI
                     VAGFVTLIAPWVGLAVSFPAALLLAATMSSTDSASVFSILRSKKQGLNENLRPLLELES
                     GSNDPMAYVLTIVLIGVLSGGAEAVSVPMSIVKFVIQMLLGGLMGYAIGRIGVWTINRI
                     NLSNYSLYPVLLLAFVFFTFSFTDLIGGNGYLAVYLAGLVLGNNQLTQKRSLTIFFDGF
                     TWLVQIVMFLTLGLLVNLDELLQPDVLMLGCLVGAFMMFIARPITVFACMMPFRKFTTK
                     ARLYVSWVGLRGAVPIIFATYPLLAGTEGARLLFNVVFLVTILSLLVQGTTVSWMANLL
                     GLGYAEKSPAFGVDVHEDIPSIFTEVLVNESMLQGGATLKEINLPENTLVMMVYRDGDY
                     FVPQGNTELKVGDKLLVISDRGEELESTYKDMGVDEVLKL"
ORIGIN
        1 atggggtacc acaatgtgta ggataaggcc ggaggcttga agcggcacgc cagtgtcgtg
       61 agcgacgtga aatacgcctt tgtgtatttg agtctaaccc tgcgaaaggg gacaccgttt
      121 ggtgggtagt ttgactgggg tggtcgcctc caaaagcgta acggaggctt cccaaggtac
      181 cctcagcacg aatggtaacc gtgcgcggag tgcaatagca taagggtgct tgactgtgag
      241 acatacaagt cgaccaggta cgaaagtagg gtatagtgat ccggtggttc tgcgtggact
      301 ggccatcgct caaaggataa aaggtactcc ggggataaca ggctgatcgc cgccaagagc
      361 tcatatcgac gcggcggttt ggcacctcga tgtcggctcg tcacatcctg gggctggaga
      421 aggtcccaag ggttcggctg ttcgccgatt aaagtggcac gcgagctggg ttcagaacgt
      481 cgtgagacag ttcggtctct atctgttgcg ggcgtaggaa gattgagggg tcctgacttt
      541 agtacgagag gaccgagttg gacgaacctc cggtgtatcg gttatgctgc caagtgtact
      601 gccgagtagc cgcgttcggt ctggataagc gctgaaagca tctaagcgcg aagccatccc
      661 caagataagt cttcccttga ggggcgtagg agactactac gttgataggc tgcaggtgta
      721 aagacagcaa tgtcaaagcc gagcagtact aattacccga taggctttct ttttcgaatc
      781 tttatctcat ctcctgtacg tgtcaaattt accggatgcg acggattata tatcgaaaag
      841 atatattcgc atagttccga tatattggag caaaagttct tttaggtggt tatagcagtg
      901 aggttccacc tcttcccatt ccgaacagag aagttaagct cactaacgcc gatggtactg
      961 cgctacgcgc gtgggagagt aggtagccgc ctcttcaagc cggatcctga acaagggtcc
     1021 ggctttcttt ttgttcgcgg gcttgcgtgt cccttcccct cgtgcggttg gctctcagcg
     1081 gcagagcctg ccaaggaggg ttatgtcggt ttagaggttg atattttgtg cctggaggtt
     1141 ggcgtgggca tacgctttac agcacgtatt cgtagtgggg ggcggtttat aaacgcagcc
     1201 aaaagccggg aatgatggcg cccgaaaccg aaatcctgtt aatgagctga atatcgtttg
     1261 aaaaatagag agaattcgtt aaattgtctt gaaataaaat caatatagcg tttcttagat
     1321 ggggccattt agcgatagat gctgaaaaat agattcggtt atgaagaaaa tattttgttt
     1381 agtttgtttt ttcttggctt tattttcgtt gaaaagcatt gctgacgttc ctgagggagc
     1441 tattccgttt gttttcgacg gacatctgta tctgcaatcg accttgaatg atactattcc
     1501 cgttaccctt atttacgata ccggagctga ctttctctat ctcgacgaag attatttgaa
     1561 actcaatcat ctgcaaaacg ctttcggacg aaaaggtaag gcaacaatgg gaggtgcggg
     1621 gaatggcgag cctgaacgca tagacatatt catcgatccg attacagtcc attgcggggc
     1681 gagggaatac caaaacgaga ttacacctat aattaagttg cgtgatctcc tcgggaggca
     1741 cactgacggc ttgttaggta atactcatct attgatgaat cctctggaaa tcaatttcag
     1801 cgagagctat ttgcgccagt taaaaggacc gttgttagct gaacagctcg ataattatgt
     1861 aaaactcgac gctcgattcg aggataaccg tatcgatgta aaggcgacgc tgcaaatcga
     1921 cgatgaaaat agcctggagg gttggtttag aatggattta gggtgcggct ccacgattat
     1981 tctcacgaat gaaacggcgt ctgcatttaa ttttatggat gtgccgaagg catatttttg
     2041 cacacaggcc ggaggtatcg gcggcggttc tgaggaggtt acgataaggg ctgcaaaatt
     2101 ctttatggcc gatacgctcg aaaatctcgt gatagattac tcgctcaatg aaaagggggc
     2161 attatcgtcg gacagaccct atataggtat aataggtaat gaaatctggt cgctctacga
     2221 cattgttttg gatccggtaa gttcttctgt atgggttaaa cgcaatgaga atcagggtac
     2281 ctacgcccaa tcgtcggtga cgcatatggc tactgttgac cgtacggata tttgcggtgg
     2341 ctggattgtc aatggcctat ataaaggagg agtcgcggag caagccggta tcgaaatcgg
     2401 tgatataatt gtagccataa ataatcgtcc tgtcaaagaa ataacctggg aagagcaacg
     2461 aaaaggtttg gaacttcagg gagaaactac atataccgtt caaaaacccg acggtcaaat
     2521 cgtttcctat actttgttta ttggtaaaca gattatctga cccaactata tcccatatag
     2581 tccggagttt gctgtttcca aaaaaattgt ggaaaggacg agtatatgtc gatatggaat
     2641 cgggaccgag gacgatcggt aaagatgccg ctcgctgcca cgggccggtt tgaatgtatg
     2701 atccatatta ttcgccgaaa aactcgcgga taattccgta tgttttgtaa gtttggggat
     2761 aattatgtgc gactatgaaa catccggtag atattgataa ttggaatcgt cgggagaact
     2821 atcttttttt ccgggatttc gccaatcctt attacagtgt tacatcgcag gtcgatgtaa
     2881 cggaagcgta tattcgggcg aaagcgctgg gtatcaagtt ttcgcactat gcgatgtacg
     2941 cttcgctacg ggctgtcaat tccattgagg cattgaggta caggcaggtc gatggaaagg
     3001 tctggctata tgatcggatc aggctcaata cggcggttgc gcgtgaggat cactcctttg
     3061 catcggttat cattccctat aatgatacgc tggaggagtt cgtcgctgaa gcgcgaggga
     3121 tcattgcagc cgcgatgcgg ggcgagggag atgcgtacgg agccgattcc gagaaggaca
     3181 cgtttgttat aagtgtgaat ccgtggtata gcttcacagg gttacagttc cagtttccgc
     3241 agaatgcagg cgagaatatc cctttgtcgg tattcggaaa gataatggtc gatatgcagg
     3301 gacgccgtac gatgcctgtg gctgtaagtt tccatcatgg gtttgtcgat ggttatcagg
     3361 tggggcgtta ttgggaggcg ttccaacata atctcgatac gctctcgatg taaaatacac
     3421 gatccgattt cggccggagt tttagtcgtt ttcaccgctg tccgcaggga caggtaggaa
     3481 caacggggaa cattgaggag gcatataaag aattatttgg cattatcatc cgtaagtcgt
     3541 atcttgcggc ggcccgattt tttgagagat ctattgtggc atcgtggggc attgtggatt
     3601 catatttgcc tgtccgaagg aggcttatgg tagcttatcc cttgtaatgg ggatggtttt
     3661 ctgtggtttt agcctgtttc ggcgattgta gaatatggat aatacggcga tctttgtaac
     3721 gtgaaaagag ataagtgtta atagggttga tgaaaggtta gagaaaaatt tttgccaaga
     3781 aattttattt gttaaagatt gtgtgtggaa aagtctgctg ggaagcagac ttttctgttt
     3841 ttgggtgcga atatttcgta ttgtccatcg ggggtattgt tttcgaaagc ccgcgcaaga
     3901 gtacgaatac cgcagagtcg atatattggc cggtcgcggc cgaaagtgaa aaaagccccg
     3961 gatgttgcat ccggggcctt tcttttgaag ggcaggttta ttatttgccc atgtagtttt
     4021 tcacgtagtg gtggtgctgt ccgtagcgct cgaatgctgc ccggtccagg gattcctggg
     4081 ccgaaggatc ggcgatcgag atgatcagcc gcgcacgctc ctgcaggctt ttgccgtaga
     4141 gattgacggc gccgttttcg gtgacgaacc agtggatgtg gttgcgggtg gttaccacgc
     4201 ctgcgccgca ggtcagttcc ggagcgatct tcgagatgcc tttgttggtc accgaaggca
     4261 tggcgataat cgccttgccg cctttcgaca gcgaagcgcc gtagatgaag tctatctggc
     4321 cgccgacacc cgaatagaat ttcgtaccca gcgaatcggc gcaaacctga ccggtgatat
     4381 ccacctggag tgccgagttg atggccgtta cgcggtcgtt cttggcgatg atgaacggat
     4441 cgttggtgta tcccacgtcc atcatcagta cgcccgggtt gtcgtcgatg aagtcgtaaa
     4501 cccgctgcga acccatcagg aaggtggaaa ccatcttgcc cttgtcgatg ttcttcgctt
     4561 cgccgttgat aacgcccttc tccaccagcg ggagaacgcc gtcggcgaac atttcggtat
     4621 ggatacccag gttcttgtgg ttgccgagct gtgccagaac cgcattcgga atagcgccga
     4681 tacccatctg aagcgtcgca ccgtcttcga tcagggccgc gcagtgcttg ccgatgcggg
     4741 tttcgatctc gttgggttcg gtgaaatgtg cctcttccag cggggtatcg tcctgtacga
     4801 agaggtcgat tttcgacgag tggatcattg cgtcgccgaa cgaacgggga acgtgcttgt
     4861 tcaccactgc gatcaccgta cgagccgttt ccacggctgc cagggtcgca tcgaccgagg
     4921 tgccgagcga aacgtagccg tgtttgtcgg gcgtcgatac ctggatcatc gctacgtcgc
     4981 aaggtaccgt gccgctgcga tagagcttct gggtttcgct caaaaagatg ggaatgtagt
     5041 ccgcatagcc gctttgcgtc actttgcgca cgttcccgcc cacgaagaac gagtcgagct
     5101 ggaagatgcc ttcgaactgc ggatcggcat agggagccgg cccttccgtg tgcaggtggt
     5161 ggatgtgcac atccttgaat tcgtggttgg cgccgcgttc gcacatggcc ttaatcaggc
     5221 actggggggc cgaagcgacc gagctgaggt gaatatggtc acccgatttg atgactttca
     5281 cggcttcggc tgccgttgtg aatttaatct gagtgttcat ttcttttttc ttattttaga
     5341 taagattcct tgcattcggt tagttgcgtt ttacctcgac ttgctcgtaa ccttcgatga
     5401 catctcctac gcggatgtcg ttgaaggatt cgatgttcag accgcagtcc tggcccgtga
     5461 gcacctcctt gacatcgtcc ttgaaccgtt tgagcgagcc gagcttgccc gtgtagatca
     5521 cgataccgtc gcggatcacg cggatcgggg tgtggcgggt cagcttgcct tctcggacga
     5581 cgcatccggc gacggtgccg actttggaaa ttcggaagat ctccatgact tccgccgagc
     5641 agacaatctc ttccttcatc accggttcga gcatgccttc gatggcatcc ttgatgtcgt
     5701 tgatcgcatc gtagatgatc gaatagaggc ggatttcgat ctcctccttt tcggcgagct
     5761 tgcgtgccga tgccgacgga cggacctgga agccgacgat gatggcattc gaggccgccg
     5821 ccaacagaac gtccgattcc gaaatctgac cgacggccga gtggatcaca ttcacctgca
     5881 cggtctcctt cgagagcttg atcagcgaac ccgacatagc ctcaaccgaa ccatcgacat
     5941 cgccttttac gatgatattc agctccttga acgatccgat ggcgatgcgg cgtccgattt
     6001 cgtcgagcgt cacgtgcttc tgggtcatga tgccctggat acgctggagt tgctcgcgtt
     6061 tgttggcgat ttcacgggcc gagcggtcgt cctccatgac gttgaacgtg tcgcctgcct
     6121 ggggagcacc gttcagaccg agcacctgta ccggcgtcga agggccagct tcggtcactt
     6181 tttggccgtt ttcgttgaac atcgctttca cacggcccgt gtgtatgccc gaaagcatta
     6241 cgtcgcctat gtgcagcgta ccgttttgta cgagcaccgt agccacgtaa ccgcggccct
     6301 tgtcgagtgt cgattcgatg acggctcccg aagcgcggcg gttcggattg gccttcaggt
     6361 cgagcatttc ggcttcgagc agcacttttt cgagcagttt gtcgagattc aggccctttt
     6421 tggccgaaac ttcctgatcc tggtatttgc cgccccacga ctccacgagg tagttcatct
     6481 gcgaaagctg ctccttgatg tggtcggggt tggctgcggg tttgtcgatc ttgttgatgg
     6541 cgaaaaccat cgggacgcct gctgcctggg cgtggttgat cgcctcgacg gtctggggca
     6601 tcacgttgtc gtccgccgcg acgatgatga tcgctacgtc ggtgattttg gcaccacggg
     6661 cgcgcatggc ggtgaaagcc tcgtggccgg gggtgtcgag gaacgtgatt ttctggccgt
     6721 tcagctctac actgtaagca ccgatgtgct gggtgatacc gcccgcctca ccttcgatga
     6781 cgttggtttt gcggatattg tccagcagcg aagtcttacc gtgatcgacg tgtcccatga
     6841 cggttacgat cggcggtcgc ggcacgaggt cttcctcgct gtcctgttcg tcgtcgccga
     6901 tggcttcctg gatgtccgcc gatacgaatt cggtcttgaa gccgaactct tcggctacga
     6961 ccacgagcgc ctcggcgtcg agacgctggt tgattgatac catcaggccc aggttcatgc
     7021 aggccgtgat gacctcggtc gccgaaacgt tcatcatcgt agccagctcg gctacggtca
     7081 cgaattcggt gaccttcagg atggagcgtt cctgctcttc gcgctggaat tcttcgttca
     7141 tgcgctcggc tacggcttcg cgtttttcct tgcggtattt cgaacctttg ctcttggcgt
     7201 ttttcgacgt caggcgggcc agtgtatctt tcacctgctt cgaaacctcc tcgtcgctga
     7261 tttcgggccg aacgacgggc ttcggagctt tgagtttgtc cttgcgggtc ttcttgttct
     7321 ctcccggacg gggttggttg gattgcgggc cttgtccgcg gccgggctgt gcggcggatt
     7381 tgccgttgct gcccggcttg gggctgcctg ccggcgtacg ggtcacgtcc actttctctt
     7441 tactcaggcg tttgcgtttg tggcggttgc ccggtgtgaa tcccgatacg tccatcgtgc
     7501 cgagtacctg cgggcccgtg agggtctgca cggcggggcg gaagatgttg tcgctcttgg
     7561 gcgccgcttc cggttcgggt ttggctgcgg aagccgtttc ggaggcaggt gccgcttccg
     7621 ttttgggggc ggccggttgc ggtgccggct gcggtttcgg agccgcagcc tccggtacgg
     7681 gctctgccgc cggtttgctt accggtttcg gagccggttt gggcttgggc gaaagatcta
     7741 ttttgcccag aattttgggc tggggcagtt cgtccttgac gctgatgacg ttgcttttga
     7801 taattacctc ctgctcctct tcgcgcgtct gtttctgtgc ctcttcgagg gtgatcgtag
     7861 cctgcttctg ggagattcgc tcccggatgc tttcccgttc gttgccggta attcggctcc
     7921 cgccgaattc cttctccaga acggcataga cgtccggttc caccagcgta ttgggcgaac
     7981 cgtcggtttt tatacccttc ttttgcagga agtccgtgat ggtattcaat cccaccttga
     8041 actccttggc aacctggata agtcttaatt ttctttcgtt actcatatat cggttttaat
     8101 ttttgtgcga tgggacggat tactcctcga attccgcttt cagtatctcg acgactttct
     8161 gtgcctgttc cagctccagg tcggcacggg cggcgatctc ttcgacgggc agttccagca
     8221 cgctcttggc cgtgtcgcag ccgcaggctt tcagggcgtc gatcacccag ccgtcgatct
     8281 cgtcggcaaa ttcggtgagt gcaacgtctt cctcctcgat ttcgcggtaa acatcgatat
     8341 cgtagccggt cagcatcttc gaaagccgga tgttcaggcc gcccttgccg atggccagcg
     8401 atacctggtc gggcttgaga tagaccgaag ctgtcttctt ctcctcgtcg atggtgatgc
     8461 tcgaaatctt cgcggggttc agggcacgct ggatcattaa ctgcgggttg gtcgtgtagt
     8521 ttaccacgtc gatattttca ttgcgcagct ccttgacgat cgagtagatg cgcgatccct
     8581 tcatgccgac gcaggcaccg accggatcga tgcgttcgtc gtaggattcg acggctacct
     8641 tggcacgctc gccggggatg cggacgatct tcttgagggt gatcagaccg tcgaaaattt
     8701 cggggacctc ctgctcgaag agccgttcga ggaactggtt ggccgtgcgc gaaaggatga
     8761 tgcgcggctg gttgttgttc atctcgacgc tcttgacgat cgccttgatc gtgtcgccct
     8821 tgcggtaata gtcgttggga atctgctcgg tcttgggcag gatcagctcg ttgccctcgt
     8881 cgtcgaggat cagcacctct ttcttccata cctgatatac ctcgccggtg atgatctcgc
     8941 cgaccttctc cgaatatttt tcgtaaaggt tggccttctc cagatcgagg atgcgcgaag
     9001 cgagattctg acgcagcgac agcacggccc gacgtccgaa cgattcaagt ttgatcggat
     9061 cgacgtattc gtcgcccact tcgtaggtcg gatcgatggc cttaacctcc gatacggcga
     9121 tttgcatgtt cggattctcc accgcgccgt cctccacgac cgtacggttt cgccagatct
     9181 ccaggtcgcc cttttccggg ttgatgatca cgtcgaaatt ctcgtccgtc tcgaactgct
     9241 tctgaagcgc gtggcggaaa acgtcctcga ggactccgat catcgtggcc ttgtcgatgt
     9301 ttttaagctc cttgaactct gcgaaattgc tgataagatt aagattatcc attggttttt
     9361 tatcttgttt atttttgaat ttccactatt tgaaatcgag gtattccttc gtgtatttga
     9421 tctctgagaa agggtagcgg cgcgtaaccc gcaccgtctg tttccgcttt ttaccctcta
     9481 cggcctgctt ctcctcgtag gagagggtga gtccctcctg gtccgcctcg tcgagcgtcg
     9541 ccagaatctt cacgccgctt ttgagcagca cttcgaccgg cttgccgatc agtttgcggt
     9601 attggcggag gtgcttgagt tccgagccga tgcctgccga agctaccgtg agggagaaat
     9661 cctccgtgtc gcggtcgaat tcggcctcga tcgcgcggct cagctccacg caggtttcga
     9721 tacctaccga ggtgtcgctg tcgatcagca gttccacttc gttggcgggc gaacaggtgc
     9781 aatccactac gaacaggtcg gtgccgacga gtttggcatt ggctatttcg gtgattttcg
     9841 tacaatcgat catatttgct gatgttatca ataaagtcgt tttccggtgc gggcagttcg
     9901 tgcaaatccg gacatctgtc cttccccggc gaaaacttga agttcgttca gtcgtttttg
     9961 cggccggccc ggaggcgttc ggctttttga cgaaaatgta ggaaatcgtc gcttcccgtt
    10021 cgttttcatc gtcttgcgtc ctgcgttttc ttcgaacatt gcatcgcaag gagcactatt
    10081 cgcgcccgaa tcttgtccct gttgtagcag gagctgtaat cgggtacccg catggcccgc
    10141 aactgccggt ttctcccgac ggaatgggca tgcgagggca tgcgggtcga gaaaatcgtg
    10201 cggatgattc gccggtcggg agcggtgaat atatctacga aataagggga cttgctcgtc
    10261 cccttacctc tctatacccg tttacgctac aaatatagcg aatgttttcc tattttcaaa
    10321 cctttgtgtc gaaaaattat tcgtcttttt cgttgctctg agagtagggc ttgataatgc
    10381 cgcgctgcga ttcgcggatg aaccggatga gtcggtcgcg ttcgggactt tgcggaatct
    10441 gtttttcgac ctcctcacag ccgttcaggt agttcaggcc gctttggaag aggatgcggc
    10501 aggcgtcgtg aatttgtgag atcgtttccg gcgtgaatcc gcggcggctc agaccgacgc
    10561 gattgacgca ggcgaaacgt accggatcgt tgttgctgac ggtgatgaag gggggaatgt
    10621 ccttgcccac cagcgcgccg ccctgaatca tcgtatgctc tccgatgcgg gtccactgat
    10681 gtacggctac gtggccgccg ataacggccc aatcgccgac ttcgacctct ccggcgagcg
    10741 atacgcggtt ggccatgacg cagtgactgc ctaccacgtc gtcgtgggcg atatgcacgt
    10801 aagccataat caggttgtgg ctgccgacga cggtcttgcc ccgggaggcg gtgccccggc
    10861 tgatggtgac gcattcgcgg atttcgttgt agtcgccgat ttctgccgtc gttttttcac
    10921 cgacgaactt caggtcctgc ggggtgcagg cgatcgatgc ggccgtatgg atcttgcagc
    10981 ctttgccgat gcgggctccg tcgtggatca cggccccggg gccgatccag cagtcgtcgc
    11041 cgatcaccac atcgccggcg atgtaggcga aaggctccac cgttacgttc tttccgagtt
    11101 tcgcgtcggg atggatgtat gcctggttgc ttatcatgtg cggttactct ttatttttaa
    11161 cgatctgggc catcatcgtg gcttcgcagg cgagcgtttc gccgacgaag gccttgcctt
    11221 cgactacggc tacgcctcgt cggatgggct ccagcagttg aacttcgaaa tgaagggtgt
    11281 cgcccggaac caccttgcgc ttgaatttta cgccgtcgat cttcatgaaa taagtcgagt
    11341 agtgctccgg atcaggaata ctgcgtaata ccagcatacc gcaacactgc gccatcgctt
    11401 cgacgatcag cacacccggc atgaccggct cttcggggaa atgtcccacg aagaatggct
    11461 cgttcatcgt gacgttcttg atgccggcta ccgtcgtgtc gtcgatgtag aagatgcggt
    11521 ccaccagcag gaacggcgga cggtggggca gcatccgccg tatatcgttg atgtcataga
    11581 cgggcggttt gcggcagtcg tattggaaac ggggcttttc gccttcgcgg cggatggtcc
    11641 gttttacctg tttcataaac tccgtgttgg cgaaatggcc gggacgagtg gcccatacgc
    11701 ggcccttgat gcgtttgccc agcaaggcga agtcgcccag caggtcgagg agcttgtggc
    11761 gggccaattc gttgttgaaa cggagctcca ggttgttcag gtagccgccc gtgatgcgga
    11821 tatcctgttt gttgaaaatt ttcttgagat gttcgagctg atcgtccggg acgggattct
    11881 ccacgacgac gatcgcgttg tccaggtcgc cgcccttgat caggttcatc ttcatcagag
    11941 gttccagatc gtgcaggaag acaaaggtgc ggcagggggc gatcttcgcg gcgtaatcgt
    12001 cttcggggtc gaatgtcgca tactggttgc cgatcacctt ggagttgtag tccacgtgca
    12061 gcgatacgga aaattcgtcg tcggggtaaa ggatgatggc cacgcctttt tccggaatcg
    12121 tatagaccat tttttcggtg acgtggtagt aggtgcgttc ggcttcctga ggttgcaggc
    12181 cggtttcgac gatcgttttc gcatattctt tggccgaacc gtccatgatc ggagtttcac
    12241 cggcatcgac atcgatcgtg gcgttgtcca cgcccagggt ccagagggcc gacatgatat
    12301 gttcgatggt cgcaacgcgt gcgccatcct tttcgatggt cgtgccccgc gaggtatccg
    12361 tgacatagtc gcatagggcc ggaatttcgg gtttgccttc caggtcgatg cggcggaaaa
    12421 cgatgccgct gttctccggg gcgggatgta ccgtcatcgt cactttgacg ccggtgtgga
    12481 ggcctgtacc tgaaaacgag atcggggctt tgagggtttg ttgtttggca gccataatct
    12541 gaatttattc aaatcgcaac atacattccc gctgactgcc gggtcccgac gtgtgtgggg
    12601 ccgaccgtca ttttcggaaa tgtttatcgc attatttgcg cgcaaatata ggaaatatta
    12661 ttcaaaaatc gtatttttgc ctaaattatt gataaaccga aattccgtgg catcacccga
    12721 cagaactcct cgtcctccga aattgcagct tcccttcgag cagaaaaaaa acgatgcggg
    12781 agaatgggct tacgaccatc ggatcggatt gtgtgtcacg ttgattgcct atttggtgct
    12841 tgcgatcgcc tttatggtgg gaaaaatcgt cgtgggggcc aaaccttccg tgcaaggcat
    12901 aatcattgat acgaaaactt tagcggagct cgaggcggag aagatgcgtc ttgaacagga
    12961 ggtacgggct cgccaacagg cgcaggaagg cggcgattgg cgggatgtgc gcaaccagta
    13021 ttccaacgag aatgcgctcg aggagcggtc gcgtgacgac cgtggctcga tgtcctcgtc
    13081 gctgaaagaa tccgccgaag cggtcggcga acggatgcag gccaaccggg acgcttacga
    13141 gcagggattg gccgaggagc gtgcgattcg ggagcgtatg gggcgcagcg gcaaggacga
    13201 tcggacacag gacagtcggg ccaggggacg ggtcacggtt tccttttcgc tgaccgatcc
    13261 cgtgcggacg cgccgttatc tggaggtgcc ggcctatcag tgcgagggag gcggcgaagt
    13321 ggtcgtcggt attacggtca atccttcggg agaggtcgtt gctgcaaaag tggcctccgg
    13381 aggcgatgac tgtatgcggg aggctgcgct ggaagctgca cgtaactcgc ttttcaatat
    13441 cgatgattcg gcgcctgccc gacagtcggg aacgattact tacctattca ttcctcaata
    13501 gggtgcggtg cctgtcagcg attgtacgcg acaggcattt tttgtaaatt tatataagga
    13561 tttcctatgc ataatatcat tacgaccgaa aacattctgt tgatcggagc cttgcttctt
    13621 ttcgtcgcgg taatggccgg caaggcggcc tatcgtttcg gcgccccggc cttgctcttt
    13681 tttctggggg tcggtatgct gttcggtatc aatttcattt cgttccattc tgtcgaagcg
    13741 acccagttcg taggtatgat cgctctttgt atcatccttt tcacgggcgg tatggatacc
    13801 aagttttcgg aaatacgacc ggtgatcgga ccgggtatcg tactggcgac cgccggagtc
    13861 gtcatgacgg cggtgatcgt agcgggtttc gtcacgctca ttgccccatg ggtcgggctg
    13921 gccgtatcgt ttcctgcggc gctgctgctg gccgcgacga tgtcttcgac ggattcggct
    13981 tcggttttct ccatcctgcg aagcaagaaa caggggctga acgagaacct gcgccctctg
    14041 ctggagctgg agagcggttc gaatgacccg atggcgtacg tgctgaccat tgtgctgatt
    14101 ggcgtattgt ccggcggtgc ggaggccgtg agcgtaccga tgagtatcgt gaaattcgtg
    14161 attcagatgc ttctcggcgg tttgatgggg tatgccatcg gtcggatcgg cgtatggacc
    14221 attaaccgca ttaacctgag caactattcg ctttacccgg tgcttttgct tgccttcgtt
    14281 ttctttacct tctcgtttac cgacctgatc ggtggcaacg gatatctggc cgtctatctg
    14341 gccggtttgg tcttggggaa taatcagctg acgcagaagc ggtcgcttac gatcttcttc
    14401 gacggcttca cctggctggt gcagatcgtg atgttcctta cgctgggtct gctcgtcaac
    14461 ctcgacgaac tcttgcagcc cgacgtgctg atgctgggat gcctggtcgg ggcttttatg
    14521 atgttcattg cgcgtcctat cacggtgttc gcctgtatga tgcctttccg caagtttacg
    14581 accaaagccc gtctttatgt ttcctgggtc ggtctgcgcg gtgccgtgcc gattattttt
    14641 gcgacctatc ctttgctggc cggtacggag ggggcacggc tgctgttcaa cgtggttttt
    14701 ctggtgacga ttctctcgct gctggtacag ggtacgaccg tgagctggat ggcgaatctg
    14761 ctcggactcg ggtatgccga aaagagtcct gccttcgggg tcgatgtcca cgaagatatt
    14821 ccgtcgatat ttaccgaggt ccttgtcaat gaatcgatgc ttcagggggg cgctacgctc
    14881 aaggagatca acctgccgga gaatacgctg gtgatgatgg tctatcgtga cggagattat
    14941 ttcgttccac agggcaatac cgaactgaag gtcggtgaca agctcttggt tatttcagac
    15001 cggggcgagg agctggagtc cacctataag gatatgggag tcgatgaagt gctgaaactt
    15061 tgagatattt cctgcagatc ggttctctct gttatcgaaa caaaaaagct gtcgttttcg
    15121 acagcttttt tgtttcgaat atatcttgaa gattagatct cccaagtagc gcccgagtgg
    15181 agcaggtcgt ccacgcagtg gatcttgctc tgggctttca cctcttccac ctgcttttca
    15241 acggcctgat cgtaaacgat ttcgtcctcg accgaacgga ttacaccgag tgcgaccgga
    15301 tagtcgggat atttcattgc
//
